UHGV-0014619

Genome information

Genome length 42,480 bps

CDS count 43

Completeness 99.90% (high-quality)

geNomad score 0.9607

Prediction confidence Confident

Genome information
Genome ID	UHGV-0014619
vOTU ID	vOTU-075623
vOTU representative	Yes
Source dataset	Hadza
Original genome ID	Nepal_MoBio_Fiber-Hadza-Nepal_B_15_RAU0016YZ__NODE_1167_length_55957_cov_5.106496_1
BioSample	NA
Country	Nepal
Virus prediction confidence	Confident

Quality assessment
CheckV method	AAI-based
CheckV completeness	99.90% (high-quality)
CheckV contamination	0.00%
Trimmed provirus	No
CheckV viral markers	9
CheckV host markers	3
Recoded stop codon	No

Viral signal
geNomad score	0.9607
Virus hallmark genes (geNomad)	6
Plasmid hallmark genes (geNomad)	0
viralVerify prediction	Uncertain - plasmid or chromosomal
viralVerify score	-1.36
Jumbo phage	No

Genome content
Genome length	42,480 bps
GC content	38.35%
Genetic code	The standard bacterial, archaeal and plant plastid code (11)
CDS count	43
CDS density	92.49%
Average CDS length	917.30 bps
tRNA count	0
Suppressor tRNA genes	0

Genome content

Select view: Genome viewer Functional annotation

Functional annotation

Gene ID	Reference	Reference ID	Information	Category
UHGV-0014619_1	KOfam	K00560	thyA, TYMS; thymidylate synthase [EC:2.1.1.45]	NA
UHGV-0014619_1	PHROG	phrog_160	thymidylate synthase	DNA, RNA and nucleotide metabolism
UHGV-0014619_1	UniRef90	UniRef90_A0A1L5KFK7	Thymidylate synthase	NA
UHGV-0014619_1	eggNOG-mapper	140626.JHWB01000013_gene500	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	NA
UHGV-0014619_1	Pfam	PF00303	Thymidylate synthase	Thymidylat_synt
UHGV-0014619_1	COG	COG0207	Thymidylate synthase	NA
UHGV-0014619_1	Structural annotation	PF00303, MF_00008, NF002499, COG0207	NA	NA
UHGV-0014619_2	KOfam	K00287	DHFR, folA; dihydrofolate reductase [EC:1.5.1.3]	NA
UHGV-0014619_2	PHROG	phrog_316	dihydrofolate reductase	DNA, RNA and nucleotide metabolism
UHGV-0014619_2	UniRef90	UniRef90_A0A1Q6U1L1	Dihydrofolate reductase	NA
UHGV-0014619_2	eggNOG-mapper	585394.RHOM_04450	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	NA
UHGV-0014619_2	Pfam	PF00186	Dihydrofolate reductase	DHFR_1
UHGV-0014619_2	COG	COG0262	Dihydrofolate reductase	NA
UHGV-0014619_2	Structural annotation	PF00186, MF_01547, NF040541, COG0262	NA	NA
UHGV-0014619_3	KOfam	K01652	E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]	NA
UHGV-0014619_3	PHROG	phrog_11199	NA	unknown function
UHGV-0014619_3	UniRef90	UniRef90_A0A173VGH5	Acetolactate synthase	NA
UHGV-0014619_3	eggNOG-mapper	622312.ROSEINA2194_02888	Acetolactate synthase, large subunit	NA
UHGV-0014619_3	Pfam	PF02776	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	TPP_enzyme_N
UHGV-0014619_3	Pfam	PF00205	Thiamine pyrophosphate enzyme, central domain	TPP_enzyme_M
UHGV-0014619_3	Pfam	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	TPP_enzyme_C
UHGV-0014619_3	NCBIFam	TIGR00118.1	biosynthetic-type acetolactate synthase large subunit	NA
UHGV-0014619_3	COG	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	NA
UHGV-0014619_4	KOfam	K01653	E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6]	NA
UHGV-0014619_4	UniRef90	UniRef90_A0A0M6WWD3	Acetolactate synthase small subunit	NA
UHGV-0014619_4	eggNOG-mapper	397290.C810_01590	ACT domain	NA
UHGV-0014619_4	Pfam	PF01842	ACT domain	ACT
UHGV-0014619_4	Pfam	PF10369	Small subunit of acetolactate synthase	ALS_ss_C
UHGV-0014619_4	NCBIFam	NF008864.0	acetolactate synthase small subunit	NA
UHGV-0014619_4	COG	COG0440	Acetolactate synthase, small subunit	NA
UHGV-0014619_5	UniRef90	UniRef90_R5YVS3	Conserved protein/domain typically associated with flavoprotein oxygenases DIM6/NTAB family	NA
UHGV-0014619_5	eggNOG-mapper	585394.RHOM_14785	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family	NA
UHGV-0014619_5	Pfam	PF01613	Flavin reductase like domain	Flavin_Reduct
UHGV-0014619_5	COG	COG1853	FMN reductase RutF, DIM6/NTAB family	NA
UHGV-0014619_6	PHROG	phrog_28785	NA	unknown function
UHGV-0014619_6	UniRef90	UniRef90_A0A174MSL2	Carboxypeptidase regulatory-like domain-containing protein	NA
UHGV-0014619_6	eggNOG-mapper	585394.RHOM_03935	Peptidoglycan binding domain protein	NA
UHGV-0014619_6	Pfam	PF08486	Stage II sporulation protein	SpoIID
UHGV-0014619_6	COG	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	NA
UHGV-0014619_6	Structural annotation	PF13620, TIGR02870, TIGR04134, COG2351	NA	NA
UHGV-0014619_7	KOfam	K06400	spoIVCA; site-specific DNA recombinase	NA
UHGV-0014619_7	PHROG	phrog_95	integrase	integration and excision
UHGV-0014619_7	UniRef90	UniRef90_C4Z7Z8	Site-specific recombinase	NA
UHGV-0014619_7	eggNOG-mapper	411462.DORLON_00823	Resolvase, N terminal domain	NA
UHGV-0014619_7	Pfam	PF00239	Resolvase, N terminal domain	Resolvase
UHGV-0014619_7	Pfam	PF07508	Recombinase	Recombinase
UHGV-0014619_7	Pfam	PF13408	Recombinase zinc beta ribbon domain	Zn_ribbon_recom
UHGV-0014619_7	COG	COG1961	Site-specific DNA recombinase SpoIVCA/DNA invertase PinE	NA
UHGV-0014619_7	Structural annotation	PF00239, PF07508, PF13408, NF041201, COG1961	NA	NA
UHGV-0014619_8	UniRef90	UniRef90_A0A174LE35	Virulence protein	NA
UHGV-0014619_8	eggNOG-mapper	1336241.JAEB01000021_gene1754	Virulence protein RhuM family	NA
UHGV-0014619_8	Pfam	PF13310	Virulence protein RhuM family	Virulence_RhuM
UHGV-0014619_8	COG	COG3943	NA	NA
UHGV-0014619_8	Structural annotation	PF13310, TIGR02681, COG3943	NA	NA
UHGV-0014619_9	eggNOG-mapper	1298920.KI911353_gene3890	NA	NA
UHGV-0014619_10	KOfam	K01356	lexA; repressor LexA [EC:3.4.21.88]	NA
UHGV-0014619_10	PHROG	phrog_4	transcriptional repressor	transcription regulation
UHGV-0014619_10	UniRef90	UniRef90_A0A355TLM1	HTH cro/C1-type domain-containing protein	NA
UHGV-0014619_10	eggNOG-mapper	478749.BRYFOR_07570	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	NA
UHGV-0014619_10	Pfam	PF01381	Helix-turn-helix	HTH_3
UHGV-0014619_10	Pfam	PF00717	Peptidase S24-like	Peptidase_S24
UHGV-0014619_10	COG	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	NA
UHGV-0014619_10	Structural annotation	PF00717, PF01381, MF_00015, TIGR00498, COG1974	NA	NA
UHGV-0014619_11	UniRef90	UniRef90_A0A0M6WGZ2	HTH_7 domain-containing protein	NA
UHGV-0014619_11	eggNOG-mapper	887929.HMP0721_1290	Helix-turn-helix domain of resolvase	NA
UHGV-0014619_11	Pfam	PF02796	Helix-turn-helix domain of resolvase	HTH_7
UHGV-0014619_11	Structural annotation	PF05339, NF041951, COG3655	NA	NA
UHGV-0014619_13	Structural annotation	PF17452	NA	NA
UHGV-0014619_16	PHROG	phrog_3584	replication initiation protein	DNA, RNA and nucleotide metabolism
UHGV-0014619_16	eggNOG-mapper	1235793.C809_01901	NA	NA
UHGV-0014619_16	Structural annotation	PF21578, NF041486	NA	NA
UHGV-0014619_17	UniRef90	UniRef90_A0A417WAJ1	HNH endonuclease	NA
UHGV-0014619_17	eggNOG-mapper	1235800.C819_02254	HNH nucleases	NA
UHGV-0014619_18	KOfam	K03497	parB, spo0J; ParB family transcriptional regulator, chromosome partitioning protein	NA
UHGV-0014619_18	PHROG	phrog_6218	ParB-like partition protein	DNA, RNA and nucleotide metabolism
UHGV-0014619_18	UniRef90	UniRef90_A0A174GZH1	Probable chromosome-partitioning protein parB	NA
UHGV-0014619_18	eggNOG-mapper	626523.GCWU000342_01034	Belongs to the ParB family	NA
UHGV-0014619_18	Pfam	PF02195	ParB/Sulfiredoxin domain	ParBc
UHGV-0014619_18	NCBIFam	TIGR00180.1	ParB/RepB/Spo0J family partition protein	NA
UHGV-0014619_18	COG	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	NA
UHGV-0014619_18	Structural annotation	PF02195, PF18579, MF_02015, TIGR00180, COG1475	NA	NA
UHGV-0014619_19	eggNOG-mapper	1235800.C819_02253	NA	NA
UHGV-0014619_19	Structural annotation	NF011508	NA	NA
UHGV-0014619_20	eggNOG-mapper	397290.C810_01492	NA	NA
UHGV-0014619_21	eggNOG-mapper	397288.C806_00101	NA	NA
UHGV-0014619_23	PHROG	phrog_874	NA	unknown function
UHGV-0014619_23	eggNOG-mapper	411468.CLOSCI_00298	NA	NA
UHGV-0014619_23	Structural annotation	PF04266, MF_00684, NF003443, COG4405	NA	NA
UHGV-0014619_24	eggNOG-mapper	478749.BRYFOR_07594	NA	NA
UHGV-0014619_26	UniRef90	UniRef90_UPI001F17D5F9	NA	NA
UHGV-0014619_26	eggNOG-mapper	1256908.HMPREF0373_00479	NA	NA
UHGV-0014619_26	Structural annotation	PF14359, COG3613	NA	NA
UHGV-0014619_28	KOfam	K07474	xtmA; phage terminase small subunit	NA
UHGV-0014619_28	PHROG	phrog_2606	terminase small subunit	head and packaging
UHGV-0014619_28	UniRef90	UniRef90_A0A416VUY5	Phage portal protein	NA
UHGV-0014619_28	eggNOG-mapper	411461.DORFOR_01162	Phage terminase, large subunit, PBSX family	NA
UHGV-0014619_28	Pfam	PF06056	Putative ATPase subunit of terminase (gpP-like)	Terminase_5
UHGV-0014619_28	Pfam	PF03592	Terminase small subunit	Terminase_2
UHGV-0014619_28	COG	COG1783	Phage terminase large subunit	NA
UHGV-0014619_28	Structural annotation	PF06056, NF040785, COG5484	NA	NA
UHGV-0014619_29	KOfam	K06909	xtmB; phage terminase large subunit	NA
UHGV-0014619_29	PHROG	phrog_979	terminase large subunit	head and packaging
UHGV-0014619_29	UniRef90	UniRef90_A0A2V2D4K5	Terminase-like family protein	NA
UHGV-0014619_29	eggNOG-mapper	748224.HMPREF9436_01395	Terminase-like family	NA
UHGV-0014619_29	Pfam	PF03237	Terminase large subunit, T4likevirus-type, N-terminal	Terminase_6N
UHGV-0014619_29	COG	COG1783	Phage terminase large subunit	NA
UHGV-0014619_29	Structural annotation	PF04466, PF20454, MF_04148, TIGR01547, COG1783	NA	NA
UHGV-0014619_30	PHROG	phrog_156	portal protein	head and packaging
UHGV-0014619_30	eggNOG-mapper	748224.HMPREF9436_01396	NA	NA
UHGV-0014619_30	Structural annotation	PF16510, MF_04120, TIGR01538, COG4383	NA	NA
UHGV-0014619_31	KOfam	K07584	NA	NA
UHGV-0014619_31	PHROG	phrog_4478	peptidase	other
UHGV-0014619_31	UniRef90	UniRef90_UPI001D081518	ribosomal-processing cysteine protease Prp	NA
UHGV-0014619_31	eggNOG-mapper	1232430.CAVG010000080_gene744	Cysteine protease Prp	NA
UHGV-0014619_31	Pfam	PF04327	Cysteine protease Prp	Peptidase_Prp
UHGV-0014619_31	COG	COG2868	NA	NA
UHGV-0014619_31	Structural annotation	PF04327, NF011133, COG2868	NA	NA
UHGV-0014619_32	PHROG	phrog_13908	NA	unknown function
UHGV-0014619_32	eggNOG-mapper	1410650.JHWL01000003_gene2831	NA	NA
UHGV-0014619_33	PHROG	phrog_1357	major head protein	head and packaging
UHGV-0014619_33	UniRef90	UniRef90_A0A3R6PQZ4	N4-gp56 family major capsid protein	NA
UHGV-0014619_33	eggNOG-mapper	657322.FPR_02330	NA	NA
UHGV-0014619_33	Pfam	PF13252	NA	DUF4043
UHGV-0014619_33	NCBIFam	TIGR04387.1	N4-gp56 family major capsid protein	NA
UHGV-0014619_33	Structural annotation	PF13252, MF_04119, TIGR04387, COG4653	NA	NA
UHGV-0014619_35	PHROG	phrog_12105	NA	unknown function
UHGV-0014619_35	eggNOG-mapper	1226322.HMPREF1545_03850	NA	NA
UHGV-0014619_36	PHROG	phrog_511	internal virion protein	head and packaging
UHGV-0014619_36	eggNOG-mapper	1321782.HMPREF1986_00351	NA	NA
UHGV-0014619_36	Structural annotation	PF11134, TIGR03300, NF038126, COG1520	NA	NA
UHGV-0014619_38	eggNOG-mapper	1410650.JHWL01000003_gene2815	NA	NA
UHGV-0014619_39	PHROG	phrog_22978	NA	unknown function
UHGV-0014619_39	UniRef90	UniRef90_A0A396KH15	PBECR3 domain-containing protein	NA
UHGV-0014619_39	eggNOG-mapper	748224.HMPREF9436_01406	NA	NA
UHGV-0014619_40	PHROG	phrog_21765	NA	unknown function
UHGV-0014619_40	eggNOG-mapper	97139.C824_05954	NA	NA
UHGV-0014619_40	Pfam	PF10651	BppU N-terminal domain	BppU_N
UHGV-0014619_41	PHROG	phrog_5717	tail protein	tail
UHGV-0014619_41	eggNOG-mapper	742742.HMPREF9452_00376	tail collar domain protein	NA
UHGV-0014619_41	COG	COG4675	Phage tail collar domain	NA
UHGV-0014619_42	PHROG	phrog_4105	NA	unknown function
UHGV-0014619_42	eggNOG-mapper	411459.RUMOBE_00911	NA	NA
UHGV-0014619_43	PHROG	phrog_443	holin	lysis
UHGV-0014619_43	UniRef90	UniRef90_UPI001C0212A6	holin	NA
UHGV-0014619_43	eggNOG-mapper	469596.HMPREF9488_02591	Putative lactococcus lactis phage r1t holin	NA
UHGV-0014619_43	Pfam	PF16945	Putative lactococcus lactis phage r1t holin	Phage_r1t_holin
UHGV-0014619_43	Structural annotation	PF16945	NA	NA