| UHGV-0017243_1 | Structural annotation | MF_00040 | NA | NA |
| UHGV-0017243_3 | PHROG | phrog_8130 | NA | unknown function |
| UHGV-0017243_3 | UniRef90 | UniRef90_A0A0S7EG45 | T5orf172 domain | NA |
| UHGV-0017243_3 | Pfam | PF13455 | Meiotically up-regulated gene 113 | MUG113 |
| UHGV-0017243_4 | UniRef90 | UniRef90_A0A843FND0 | BlaI/MecI/CopY family transcriptional regulator | NA |
| UHGV-0017243_4 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |
| UHGV-0017243_6 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |
| UHGV-0017243_11 | PHROG | phrog_20187 | NA | unknown function |
| UHGV-0017243_11 | UniRef90 | UniRef90_A0A345BPQ2 | Putative Pol III-like exoribonuclease | NA |
| UHGV-0017243_11 | Structural annotation | PF21762, MF_00045, NF006316, COG0847 | NA | NA |
| UHGV-0017243_15 | PHROG | phrog_420 | NA | unknown function |
| UHGV-0017243_15 | UniRef90 | UniRef90_A0A358WEC8 | AAA_31 domain-containing protein | NA |
| UHGV-0017243_15 | eggNOG-mapper | 1408311.JNJM01000010_gene958 | 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) | NA |
| UHGV-0017243_15 | Pfam | PF06941 | 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) | NT5C |
| UHGV-0017243_15 | Structural annotation | PF06941, MF_01681, NF011564, COG4502 | NA | NA |
| UHGV-0017243_19 | PHROG | phrog_5767 | sigma factor | transcription regulation |
| UHGV-0017243_19 | UniRef90 | UniRef90_A0A345BPU6 | HTH DNA binding domain protein | NA |
| UHGV-0017243_19 | eggNOG-mapper | 1123239.KB898628_gene3218 | NA | NA |
| UHGV-0017243_20 | PHROG | phrog_3314 | NA | unknown function |
| UHGV-0017243_21 | PHROG | phrog_15503 | NA | unknown function |
| UHGV-0017243_21 | eggNOG-mapper | 1560313.A0A0D3MT14_9CAUD | NA | NA |
| UHGV-0017243_22 | PHROG | phrog_24618 | NA | unknown function |
| UHGV-0017243_22 | UniRef90 | UniRef90_A0A0H3V0N0 | Putative terminase large subunit | NA |
| UHGV-0017243_22 | eggNOG-mapper | 881953.E0YJ34_9CAUD | NA | NA |
| UHGV-0017243_22 | Structural annotation | PF20441, MF_04146, TIGR01547, COG4373 | NA | NA |
| UHGV-0017243_23 | PHROG | phrog_9084 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_23 | UniRef90 | UniRef90_A0A4R1ASL1 | NA | NA |
| UHGV-0017243_23 | eggNOG-mapper | 397291.C804_06294 | transposase activity | NA |
| UHGV-0017243_23 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-0017243_23 | Structural annotation | PF18741, MF_04160, NF007294, COG2852 | NA | NA |
| UHGV-0017243_24 | PHROG | phrog_2739 | portal protein | head and packaging |
| UHGV-0017243_24 | UniRef90 | UniRef90_A0A345BPV2 | Putative portal protein | NA |
| UHGV-0017243_24 | eggNOG-mapper | 1308863.U5J9V5_9CAUD | NA | NA |
| UHGV-0017243_24 | Structural annotation | PF05133, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0017243_25 | PHROG | phrog_3313 | NA | unknown function |
| UHGV-0017243_25 | UniRef90 | UniRef90_A0A7S6RBM7 | Putative prohead protease | NA |
| UHGV-0017243_25 | eggNOG-mapper | 1308863.U5J9D4_9CAUD | NA | NA |
| UHGV-0017243_25 | Structural annotation | PF09979, TIGR01543, COG3566 | NA | NA |
| UHGV-0017243_26 | PHROG | phrog_35301 | NA | unknown function |
| UHGV-0017243_27 | PHROG | phrog_4088 | NA | unknown function |
| UHGV-0017243_27 | eggNOG-mapper | 1541960.KQ78_01850 | NA | NA |
| UHGV-0017243_27 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0017243_28 | PHROG | phrog_30998 | NA | unknown function |
| UHGV-0017243_29 | PHROG | phrog_3853 | NA | unknown function |
| UHGV-0017243_29 | eggNOG-mapper | 1308863.U5J9G6_9CAUD | NA | NA |
| UHGV-0017243_30 | PHROG | phrog_29637 | NA | unknown function |
| UHGV-0017243_30 | Structural annotation | PF14276 | NA | NA |
| UHGV-0017243_31 | UniRef90 | UniRef90_A0A345BPV9 | Ig domain protein | NA |
| UHGV-0017243_31 | Structural annotation | PF19408, PF11649, NF041894, COG5614 | NA | NA |
| UHGV-0017243_32 | PHROG | phrog_6123 | virion structural protein | head and packaging |
| UHGV-0017243_32 | Structural annotation | PF06141 | NA | NA |
| UHGV-0017243_33 | PHROG | phrog_4051 | NA | unknown function |
| UHGV-0017243_34 | PHROG | phrog_2729 | virion structural protein | head and packaging |
| UHGV-0017243_34 | eggNOG-mapper | 1196323.ALKF01000158_gene820 | NA | NA |
| UHGV-0017243_36 | PHROG | phrog_30570 | NA | unknown function |
| UHGV-0017243_37 | KOfam | K20478 | GOLGB1; golgin subfamily B member 1 | NA |
| UHGV-0017243_37 | PHROG | phrog_28 | tail length tape measure protein | tail |
| UHGV-0017243_37 | UniRef90 | UniRef90_A0A345BQ07 | Tail tape protein | NA |
| UHGV-0017243_37 | eggNOG-mapper | 1200792.AKYF01000010_gene2581 | Phage-related minor tail protein | NA |
| UHGV-0017243_37 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0017243_37 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0017243_37 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0017243_38 | PHROG | phrog_21973 | tail protein | tail |
| UHGV-0017243_38 | eggNOG-mapper | 1211844.CBLM010000023_gene978 | cellulase activity | NA |
| UHGV-0017243_38 | COG | COG4733 | Phage-related protein, tail protein J | NA |
| UHGV-0017243_41 | PHROG | phrog_24267 | NA | unknown function |
| UHGV-0017243_41 | UniRef90 | UniRef90_A0A099I3H7 | Pilus assembly protein (Fragment) | NA |
| UHGV-0017243_41 | eggNOG-mapper | 411490.ANACAC_00723 | the current gene model (or a revised gene model) may contain a frame shift | NA |
| UHGV-0017243_41 | COG | COG4675 | Phage tail collar domain | NA |
| UHGV-0017243_42 | PHROG | phrog_2459 | NA | unknown function |
| UHGV-0017243_42 | UniRef90 | UniRef90_R5Z2C8 | Peptidoglycan-binding domain 1 protein | NA |
| UHGV-0017243_42 | eggNOG-mapper | 717606.PaecuDRAFT_1762 | Papain-like cysteine protease AvrRpt2 | NA |
| UHGV-0017243_42 | Pfam | PF13529 | Peptidase_C39 like family | Peptidase_C39_2 |
| UHGV-0017243_42 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-0017243_42 | COG | COG0768 | Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) | NA |
| UHGV-0017243_42 | Structural annotation | PF03412, PF08239, PF18341, NF040678, NF033920, COG4991, COG4990 | NA | NA |
| UHGV-0017243_44 | eggNOG-mapper | 476272.RUMHYD_00002 | NA | NA |
| UHGV-0017243_46 | PHROG | phrog_30026 | NA | unknown function |
| UHGV-0017243_46 | Structural annotation | PF02010, PF06995, NF040520, COG4718, COG2372 | NA | NA |
| UHGV-0017243_47 | PHROG | phrog_32343 | NA | unknown function |
| UHGV-0017243_47 | UniRef90 | UniRef90_A0A345BPW9 | Putative flagellin-like protein | NA |
| UHGV-0017243_47 | eggNOG-mapper | 483218.BACPEC_01060 | NA | NA |
| UHGV-0017243_47 | Structural annotation | PF14594, NF033848, COG4379 | NA | NA |
| UHGV-0017243_48 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-0017243_48 | eggNOG-mapper | 658655.HMPREF0988_00919 | NA | NA |
| UHGV-0017243_49 | eggNOG-mapper | 476272.RUMHYD_01953 | NA | NA |
| UHGV-0017243_50 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0017243_50 | eggNOG-mapper | 397290.C810_01328 | NA | NA |
| UHGV-0017243_51 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-0017243_51 | UniRef90 | UniRef90_A0A345BPX4 | Carbohydrate binding domain/collagen triple helix repeat protein | NA |
| UHGV-0017243_51 | eggNOG-mapper | 1226322.HMPREF1545_00077 | NA | NA |
| UHGV-0017243_51 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-0017243_52 | eggNOG-mapper | 658655.HMPREF0988_00915 | NA | NA |
| UHGV-0017243_53 | PHROG | phrog_827 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_53 | UniRef90 | UniRef90_A0A345BPU5 | Crossover junction endodeoxyribonuclease RuvC | NA |
| UHGV-0017243_53 | COG | COG0817 | Holliday junction resolvasome RuvABC endonuclease subunit RuvC | NA |
| UHGV-0017243_53 | Structural annotation | PF07066, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-0017243_55 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-0017243_55 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_55 | UniRef90 | UniRef90_A0A0M6WDV6 | DeoxyUTP pyrophosphatase | NA |
| UHGV-0017243_55 | eggNOG-mapper | 622312.ROSEINA2194_00085 | This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | NA |
| UHGV-0017243_55 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-0017243_55 | NCBIFam | TIGR00576.1 | dUTP diphosphatase | NA |
| UHGV-0017243_55 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-0017243_55 | Structural annotation | PF00692, MF_00116, NF001862, COG0756 | NA | NA |
| UHGV-0017243_56 | Structural annotation | PF10750, MF_01122, TIGR00285, COG1581 | NA | NA |
| UHGV-0017243_57 | KOfam | K07192 | FLOT; flotillin | NA |
| UHGV-0017243_57 | UniRef90 | UniRef90_UPI00164EBA4A | flotillin family protein | NA |
| UHGV-0017243_57 | eggNOG-mapper | 397291.C804_00311 | Flotillin | NA |
| UHGV-0017243_57 | Pfam | PF15975 | Flotillin | Flot |
| UHGV-0017243_57 | COG | COG2268 | NA | NA |
| UHGV-0017243_58 | KOfam | K07192 | FLOT; flotillin | NA |
| UHGV-0017243_58 | UniRef90 | UniRef90_UPI001E3D4848 | flotillin family protein | NA |
| UHGV-0017243_58 | eggNOG-mapper | 1384066.JAGT01000001_gene1386 | Flotillin | NA |
| UHGV-0017243_58 | Pfam | PF01145 | SPFH domain / Band 7 family | Band_7 |
| UHGV-0017243_58 | COG | COG2268 | NA | NA |
| UHGV-0017243_59 | Structural annotation | PF18844, NF001026, COG4820 | NA | NA |
| UHGV-0017243_61 | PHROG | phrog_20637 | NA | unknown function |
| UHGV-0017243_61 | eggNOG-mapper | 575593.HMPREF0491_00728 | NA | NA |
| UHGV-0017243_61 | Pfam | PF18907 | NA | DUF5662 |
| UHGV-0017243_61 | Structural annotation | PF18907 | NA | NA |
| UHGV-0017243_63 | PHROG | phrog_1818 | NA | unknown function |
| UHGV-0017243_63 | UniRef90 | UniRef90_UPI0013F9361D | HAD domain-containing protein | NA |
| UHGV-0017243_63 | eggNOG-mapper | 707757.D5JFP2_9CAUD | NA | NA |
| UHGV-0017243_63 | Pfam | PF18143 | HAD domain in Swiss Army Knife RNA repair proteins | HAD_SAK_2 |
| UHGV-0017243_63 | Structural annotation | PF18143, TIGR01261 | NA | NA |
| UHGV-0017243_65 | KOfam | K01462 | PDF, def; peptide deformylase [EC:3.5.1.88] | NA |
| UHGV-0017243_65 | PHROG | phrog_2890 | peptide deformylase | other |
| UHGV-0017243_65 | UniRef90 | UniRef90_A0A4Y6PZH8 | Peptide deformylase | NA |
| UHGV-0017243_65 | eggNOG-mapper | 1379858.N508_00094 | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions | NA |
| UHGV-0017243_65 | Pfam | PF01327 | Polypeptide deformylase | Pep_deformylase |
| UHGV-0017243_65 | NCBIFam | TIGR00079.1 | peptide deformylase | NA |
| UHGV-0017243_65 | COG | COG0242 | Peptide deformylase | NA |
| UHGV-0017243_65 | HAMAP | MF_00163 | Peptide deformylase [def] | NA |
| UHGV-0017243_65 | Structural annotation | PF01327, MF_00163, NF006670, COG0242 | NA | NA |
| UHGV-0017243_66 | KOfam | K04068 | nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] | NA |
| UHGV-0017243_66 | PHROG | phrog_626 | anaerobic ribonucleotide reductase small subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_66 | UniRef90 | UniRef90_UPI001651A4D2 | anaerobic ribonucleoside-triphosphate reductase activating protein | NA |
| UHGV-0017243_66 | eggNOG-mapper | 445973.CLOBAR_00582 | Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine | NA |
| UHGV-0017243_66 | Pfam | PF13353 | 4Fe-4S single cluster domain | Fer4_12 |
| UHGV-0017243_66 | NCBIFam | TIGR02491.1 | anaerobic ribonucleoside-triphosphate reductase activating protein | NA |
| UHGV-0017243_66 | COG | COG0602 | Organic radical activating enzyme NrdG/QueE | NA |
| UHGV-0017243_66 | Structural annotation | PF13353, MF_00917, TIGR02491, COG0602 | NA | NA |
| UHGV-0017243_67 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-0017243_67 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-0017243_67 | UniRef90 | UniRef90_A0A496NMN0 | Anaerobic ribonucleoside-triphosphate reductase (Fragment) | NA |
| UHGV-0017243_67 | eggNOG-mapper | 742735.HMPREF9467_00913 | anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0017243_67 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-0017243_67 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0017243_67 | Structural annotation | PF13597, TIGR02487, COG1328 | NA | NA |
| UHGV-0017243_68 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-0017243_68 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-0017243_68 | UniRef90 | UniRef90_R5Y9X4 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0017243_68 | eggNOG-mapper | 500635.MITSMUL_03099 | Ribonucleoside-triphosphate reductase | NA |
| UHGV-0017243_68 | Pfam | PF03477 | ATP cone domain | ATP-cone |
| UHGV-0017243_68 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-0017243_68 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0017243_68 | Structural annotation | PF13597, PF03477, MF_00440, NF006732, COG1328 | NA | NA |
| UHGV-0017243_69 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-0017243_69 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-0017243_69 | UniRef90 | UniRef90_A0A345BQ01 | GMPK protein | NA |
| UHGV-0017243_69 | eggNOG-mapper | 1298920.KI911353_gene5090 | Guanylate kinase homologues. | NA |
| UHGV-0017243_69 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-0017243_69 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-0017243_69 | Structural annotation | PF00625, MF_00328, NF011324, COG0194 | NA | NA |
| UHGV-0017243_70 | KOfam | K02337 | dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] | NA |
| UHGV-0017243_70 | PHROG | phrog_405 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_70 | UniRef90 | UniRef90_A0A843GL03 | DNA-directed DNA polymerase | NA |
| UHGV-0017243_70 | eggNOG-mapper | 224308.BSU20340 | DNA polymerase | NA |
| UHGV-0017243_70 | Pfam | PF02811 | PHP domain | PHP |
| UHGV-0017243_70 | Pfam | PF07733 | Bacterial DNA polymerase III alpha NTPase domain | DNA_pol3_alpha |
| UHGV-0017243_70 | Pfam | PF17657 | Bacterial DNA polymerase III alpha subunit finger domain | DNA_pol3_finger |
| UHGV-0017243_70 | Pfam | PF14579 | Helix-hairpin-helix motif | HHH_6 |
| UHGV-0017243_70 | COG | COG0587 | DNA polymerase III, alpha subunit | NA |
| UHGV-0017243_70 | Structural annotation | PF07733, PF02811, PF17657, PF14579, MF_01902, NF005617, COG0587 | NA | NA |
| UHGV-0017243_71 | Structural annotation | COG3189 | NA | NA |
| UHGV-0017243_72 | KOfam | K03581 | recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] | NA |
| UHGV-0017243_72 | PHROG | phrog_325 | Dda-like helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_72 | UniRef90 | UniRef90_A0A843GQ82 | AAA family ATPase | NA |
| UHGV-0017243_72 | eggNOG-mapper | 1541960.KQ78_01910 | A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD | NA |
| UHGV-0017243_72 | PADLOC | cluster10 | RecD_0_IVD | CRISPR-CAS |
| UHGV-0017243_72 | Pfam | PF13604 | AAA domain | AAA_30 |
| UHGV-0017243_72 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0017243_75 | KOfam | K07462 | recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] | NA |
| UHGV-0017243_75 | PHROG | phrog_2484 | RecJ-like ssDNA exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_75 | UniRef90 | UniRef90_A0A843GQK3 | DHH family phosphoesterase | NA |
| UHGV-0017243_75 | eggNOG-mapper | 224308.BSU20350 | Single-stranded-DNA-specific exonuclease RecJ | NA |
| UHGV-0017243_75 | Pfam | PF01368 | DHH family | DHH |
| UHGV-0017243_75 | COG | COG0608 | ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation | NA |
| UHGV-0017243_75 | Structural annotation | PF17768, PF02272, MF_00207, TIGR00644, COG0608 | NA | NA |
| UHGV-0017243_77 | KOfam | K02316 | dnaG; DNA primase [EC:2.7.7.101] | NA |
| UHGV-0017243_77 | PHROG | phrog_47 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_77 | UniRef90 | UniRef90_A0A345BPU0 | DNA primase | NA |
| UHGV-0017243_77 | eggNOG-mapper | 1582152.A0A0A8WIQ8_9CAUD | CHC2 zinc finger | NA |
| UHGV-0017243_77 | Structural annotation | PF19898, MF_00974, NF006382, COG0353 | NA | NA |
| UHGV-0017243_79 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0017243_79 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_79 | UniRef90 | UniRef90_A0A843FNV1 | DNA helicase | NA |
| UHGV-0017243_79 | eggNOG-mapper | 537007.BLAHAN_05495 | DnaB-like helicase C terminal domain | NA |
| UHGV-0017243_79 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-0017243_79 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0017243_79 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0017243_79 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0017243_80 | PHROG | phrog_4680 | NA | unknown function |
| UHGV-0017243_80 | UniRef90 | UniRef90_A0A3S4N9I4 | NA | NA |
| UHGV-0017243_80 | eggNOG-mapper | 176279.SERP1593 | NA | NA |
| UHGV-0017243_81 | PHROG | phrog_124 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_81 | UniRef90 | UniRef90_A0A843GMB3 | ATP-binding protein | NA |
| UHGV-0017243_81 | eggNOG-mapper | 1541960.KQ78_01919 | Belongs to the helicase family. UvrD subfamily | NA |
| UHGV-0017243_81 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-0017243_81 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-0017243_81 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-0017243_82 | PHROG | phrog_2367 | NA | unknown function |
| UHGV-0017243_82 | eggNOG-mapper | 742735.HMPREF9467_00888 | NA | NA |
| UHGV-0017243_82 | Structural annotation | PF00436, PF19649, MF_00984, NF004476, COG2965 | NA | NA |
| UHGV-0017243_83 | UniRef90 | UniRef90_A0A345BPT4 | LexA repressor | NA |
| UHGV-0017243_83 | Structural annotation | PF03444, MF_00732, TIGR02337, COG1321 | NA | NA |
| UHGV-0017243_84 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0017243_84 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_84 | UniRef90 | UniRef90_A0A1Q6K5G9 | Thymidylate synthase, flavin-dependent | NA |
| UHGV-0017243_84 | eggNOG-mapper | 1216932.CM240_2226 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant | NA |
| UHGV-0017243_84 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0017243_84 | NCBIFam | TIGR02170.1 | FAD-dependent thymidylate synthase | NA |
| UHGV-0017243_84 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0017243_84 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0017243_85 | PHROG | phrog_5123 | homing endonuclease with GIY-YIG motif | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_85 | UniRef90 | UniRef90_A0A843GN52 | GIY-YIG nuclease family protein | NA |
| UHGV-0017243_85 | eggNOG-mapper | 1427984.X271_00109 | NA | NA |
| UHGV-0017243_85 | PADLOC | HEase_00022 | homing endonuclease | RM |
| UHGV-0017243_85 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0017243_85 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0017243_85 | Structural annotation | PF19835, TIGR01453 | NA | NA |
| UHGV-0017243_86 | Structural annotation | PF04182, MF_01909, NF040939, COG1675 | NA | NA |
| UHGV-0017243_88 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-0017243_88 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_88 | UniRef90 | UniRef90_A0A6N7SQR9 | BRCT domain-containing protein | NA |
| UHGV-0017243_88 | eggNOG-mapper | 537007.BLAHAN_05473 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-0017243_88 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-0017243_88 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0017243_88 | Structural annotation | PF00533, TIGR00575 | NA | NA |
| UHGV-0017243_89 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-0017243_89 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_89 | UniRef90 | UniRef90_A0A832SWP0 | DNA ligase (NAD(+)) (Fragment) | NA |
| UHGV-0017243_89 | eggNOG-mapper | 1235802.C823_04644 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-0017243_89 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-0017243_89 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0017243_89 | Structural annotation | PF01653, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-0017243_91 | KOfam | K02469 | gyrA; DNA gyrase subunit A [EC:5.6.2.2] | NA |
| UHGV-0017243_91 | PHROG | phrog_551 | DNA topoisomerase II | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_91 | UniRef90 | UniRef90_A0A832SNJ2 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0017243_91 | eggNOG-mapper | 33035.JPJF01000072_gene4351 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0017243_91 | Pfam | PF00521 | DNA gyrase/topoisomerase IV, subunit A | DNA_topoisoIV |
| UHGV-0017243_91 | Pfam | PF03989 | DNA gyrase C-terminal domain, beta-propeller | DNA_gyraseA_C |
| UHGV-0017243_91 | NCBIFam | NF004044.1 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0017243_91 | COG | COG0188 | DNA gyrase/topoisomerase IV, subunit A | NA |
| UHGV-0017243_91 | Structural annotation | PF00521, PF03989, MF_01897, NF004043, COG0188 | NA | NA |
| UHGV-0017243_92 | KOfam | K02470 | gyrB; DNA gyrase subunit B [EC:5.6.2.2] | NA |
| UHGV-0017243_92 | PHROG | phrog_543 | DNA topoisomerase II large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_92 | UniRef90 | UniRef90_A0A832SWV5 | DNA topoisomerase IV subunit B | NA |
| UHGV-0017243_92 | eggNOG-mapper | 511680.BUTYVIB_00379 | TopoisomeraseII | NA |
| UHGV-0017243_92 | Pfam | PF01751 | Toprim domain | Toprim |
| UHGV-0017243_92 | Pfam | PF00986 | DNA gyrase B subunit, carboxyl terminus | DNA_gyraseB_C |
| UHGV-0017243_92 | COG | COG0187 | DNA gyrase/topoisomerase IV, subunit B | NA |
| UHGV-0017243_93 | PHROG | phrog_7168 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_93 | UniRef90 | UniRef90_UPI0011A028AF | GIY-YIG nuclease family protein | NA |
| UHGV-0017243_93 | eggNOG-mapper | 1280692.AUJL01000004_gene859 | GIY-YIG type nucleases (URI domain) | NA |
| UHGV-0017243_93 | PADLOC | HEase_00022 | homing endonuclease | RM |
| UHGV-0017243_93 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0017243_93 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0017243_93 | Structural annotation | PF19835, PF02796, TIGR01453 | NA | NA |
| UHGV-0017243_94 | KOfam | K02470 | gyrB; DNA gyrase subunit B [EC:5.6.2.2] | NA |
| UHGV-0017243_94 | PHROG | phrog_543 | DNA topoisomerase II large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_94 | UniRef90 | UniRef90_A0A385NI95 | DNA topoisomerase (ATP-hydrolyzing) (Fragment) | NA |
| UHGV-0017243_94 | eggNOG-mapper | 1112204.GPOL_c00060 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0017243_94 | Pfam | PF00204 | DNA gyrase B | DNA_gyraseB |
| UHGV-0017243_94 | COG | COG0187 | DNA gyrase/topoisomerase IV, subunit B | NA |
| UHGV-0017243_95 | KOfam | K03469 | rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4] | NA |
| UHGV-0017243_95 | PHROG | phrog_531 | Rnase H | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_95 | UniRef90 | UniRef90_A0A5C0UIH7 | Ribonuclease H | NA |
| UHGV-0017243_95 | eggNOG-mapper | 1265756.AWZW01000008_gene588 | Endonuclease that specifically degrades the RNA of RNA- DNA hybrids | NA |
| UHGV-0017243_95 | Pfam | PF00075 | RNase H | RNase_H |
| UHGV-0017243_95 | COG | COG0328 | Ribonuclease HI | NA |
| UHGV-0017243_96 | PHROG | phrog_608 | holin | lysis |
| UHGV-0017243_96 | UniRef90 | UniRef90_UPI0019604BA7 | phage holin, LLH family | NA |
| UHGV-0017243_96 | eggNOG-mapper | 767817.Desgi_4695 | Bacteriophage holin of superfamily 6 (Holin_LLH) | NA |
| UHGV-0017243_96 | Pfam | PF09682 | Bacteriophage holin of superfamily 6 (Holin_LLH) | Phage_holin_6_1 |
| UHGV-0017243_96 | NCBIFam | TIGR01673.1 | phage holin | NA |
| UHGV-0017243_96 | Structural annotation | PF09682, TIGR01673 | NA | NA |
| UHGV-0017243_97 | Structural annotation | PF21662 | NA | NA |
| UHGV-0017243_98 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-0017243_98 | UniRef90 | UniRef90_A0A1I0M725 | Calcineurin-like phosphoesterase superfamily protein | NA |
| UHGV-0017243_98 | eggNOG-mapper | 1392491.JIAE01000001_gene1129 | Calcineurin-like phosphoesterase | NA |
| UHGV-0017243_98 | Pfam | PF12850 | Calcineurin-like phosphoesterase superfamily domain | Metallophos_2 |
| UHGV-0017243_98 | COG | COG4186 | NA | NA |
| UHGV-0017243_98 | Structural annotation | NF006988, COG4186 | NA | NA |
| UHGV-0017243_99 | PHROG | phrog_388 | nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_99 | UniRef90 | UniRef90_A0A843FSU3 | Nucleotidyltransferase domain-containing protein | NA |
| UHGV-0017243_99 | eggNOG-mapper | 1236973.JCM9157_1946 | Predicted nucleotidyltransferase | NA |
| UHGV-0017243_99 | Structural annotation | PF10127, NF000079, COG3541 | NA | NA |
| UHGV-0017243_100 | COG | COG4639 | Predicted kinase | NA |
| UHGV-0017243_101 | PHROG | phrog_2255 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_101 | UniRef90 | UniRef90_A0A513ZZZ0 | HNH domain-containing protein | NA |
| UHGV-0017243_101 | eggNOG-mapper | 1541960.KQ78_01975 | HNH nucleases | NA |
| UHGV-0017243_102 | PHROG | phrog_1257 | ribosome associated inhibitor A; zinc finger domain | moron, auxiliary metabolic gene and host takeover |
| UHGV-0017243_104 | KOfam | K18962 | rnlB; T4 RNA ligase 2 [EC:6.5.1.3] | NA |
| UHGV-0017243_104 | PHROG | phrog_968 | RNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_104 | UniRef90 | UniRef90_A0A3B9Z7W5 | RNA_ligase domain-containing protein | NA |
| UHGV-0017243_104 | eggNOG-mapper | 223192.XP_007918367.1 | RNA ligase | NA |
| UHGV-0017243_104 | Pfam | PF21189 | PHA02142 OB-fold domain | PHA02142 |
| UHGV-0017243_104 | Pfam | PF09414 | RNA ligase | RNA_ligase |
| UHGV-0017243_104 | Structural annotation | PF21189, PF09511, MF_04150, TIGR02306, COG1423, COG0073 | NA | NA |
| UHGV-0017243_105 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_105 | UniRef90 | UniRef90_A0A328L1C0 | HNHc domain-containing protein | NA |
| UHGV-0017243_105 | eggNOG-mapper | 1129192.A0A0E3D9P0_9CAUD | HNH endonuclease | NA |
| UHGV-0017243_105 | PADLOC | HEase_00016 | homing endonuclease | RM |
| UHGV-0017243_105 | Pfam | PF13392 | HNH endonuclease | HNH_3 |
| UHGV-0017243_105 | Structural annotation | PF07463, PF07453, TIGR01453 | NA | NA |
| UHGV-0017243_106 | Structural annotation | PF10127, PF08222, MF_00621, TIGR02787, NF000079, COG4465, COG3541 | NA | NA |
| UHGV-0017243_109 | Structural annotation | PF19110, MF_01909, NF040939, COG1695 | NA | NA |
| UHGV-0017243_110 | UniRef90 | UniRef90_A0A345BPS5 | Putative protease | NA |
| UHGV-0017243_110 | Structural annotation | PF02581, MF_02232, TIGR01182, COG0135 | NA | NA |
| UHGV-0017243_111 | PHROG | phrog_22529 | NA | unknown function |
| UHGV-0017243_111 | UniRef90 | UniRef90_A0A345BPD4 | 3D containing protein | NA |
| UHGV-0017243_111 | eggNOG-mapper | 411489.CLOL250_00650 | 3D domain protein | NA |
| UHGV-0017243_111 | Pfam | PF06725 | 3D domain | 3D |
| UHGV-0017243_111 | COG | COG3584 | 3D (Asp-Asp-Asp) domain, usually in lytic transglycosylases | NA |
| UHGV-0017243_114 | KOfam | K00600 | glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] | NA |
| UHGV-0017243_114 | UniRef90 | UniRef90_A0A2M6W2K7 | Serine hydroxymethyltransferase (Fragment) | NA |
| UHGV-0017243_114 | eggNOG-mapper | 484019.THA_1054 | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | NA |
| UHGV-0017243_114 | Pfam | PF00464 | Serine hydroxymethyltransferase | SHMT |
| UHGV-0017243_114 | COG | COG0112 | Glycine/serine hydroxymethyltransferase | NA |
| UHGV-0017243_115 | KOfam | K00600 | glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] | NA |
| UHGV-0017243_115 | PHROG | phrog_9968 | methyltransferase | other |
| UHGV-0017243_115 | UniRef90 | UniRef90_A0A6N8HMD3 | Glycine hydroxymethyltransferase | NA |
| UHGV-0017243_115 | eggNOG-mapper | 864565.HMPREF0379_0386 | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | NA |
| UHGV-0017243_115 | Pfam | PF00464 | Serine hydroxymethyltransferase | SHMT |
| UHGV-0017243_115 | COG | COG0112 | Glycine/serine hydroxymethyltransferase | NA |
| UHGV-0017243_116 | KOfam | K00600 | glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] | NA |
| UHGV-0017243_116 | PHROG | phrog_9968 | methyltransferase | other |
| UHGV-0017243_116 | UniRef90 | UniRef90_A0A7X6Y9D6 | Serine hydroxymethyltransferase | NA |
| UHGV-0017243_116 | eggNOG-mapper | 411461.DORFOR_02150 | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | NA |
| UHGV-0017243_116 | Pfam | PF00464 | Serine hydroxymethyltransferase | SHMT |
| UHGV-0017243_116 | COG | COG0112 | Glycine/serine hydroxymethyltransferase | NA |
| UHGV-0017243_117 | Pfam | PF00011 | Hsp20/alpha crystallin family | HSP20 |
| UHGV-0017243_117 | COG | COG0071 | Small heat shock protein IbpA, HSP20 family | NA |
| UHGV-0017243_117 | Structural annotation | PF00011, MF_02000, NF041799, COG0071 | NA | NA |
| UHGV-0017243_127 | PHROG | phrog_1828 | NA | unknown function |
| UHGV-0017243_130 | KOfam | K19304 | mepM; murein DD-endopeptidase [EC:3.4.24.-] | NA |
| UHGV-0017243_130 | PHROG | phrog_6700 | endolysin | lysis |
| UHGV-0017243_130 | UniRef90 | UniRef90_UPI00193FF1DC | M23 family metallopeptidase | NA |
| UHGV-0017243_130 | eggNOG-mapper | 1131462.DCF50_p656 | PFAM Peptidase family M23 | NA |
| UHGV-0017243_130 | Pfam | PF01551 | Peptidase family M23 | Peptidase_M23 |
| UHGV-0017243_130 | COG | COG0739 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain | NA |
| UHGV-0017243_131 | PHROG | phrog_9116 | tail protein | tail |
| UHGV-0017243_131 | eggNOG-mapper | 1430440.MGMSRv2_2248 | Phage Tail Collar Domain | NA |
| UHGV-0017243_131 | Pfam | PF07484 | Phage Tail Collar Domain | Collar |
| UHGV-0017243_131 | COG | COG4675 | Phage tail collar domain | NA |
| UHGV-0017243_132 | UniRef90 | UniRef90_A0A345BPC8 | Tail fiber protein | NA |
| UHGV-0017243_133 | eggNOG-mapper | 411470.RUMGNA_00122 | NA | NA |
| UHGV-0017243_135 | Structural annotation | PF20010 | NA | NA |
| UHGV-0017243_136 | PHROG | phrog_850 | RNA-binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0017243_136 | UniRef90 | UniRef90_A0A843FJC6 | NA | NA |
| UHGV-0017243_136 | eggNOG-mapper | 1541960.KQ78_01972 | oxidoreductase activity | NA |
| UHGV-0017243_136 | Pfam | PF11443 | NA | DUF2828 |
| UHGV-0017243_136 | COG | COG2304 | Secreted protein containing bacterial Ig-like domain and vWFA domain | NA |
| UHGV-0017243_136 | Structural annotation | PF11443, MF_01340, COG2304 | NA | NA |
| UHGV-0017243_138 | PHROG | phrog_1649 | metallo-phosphoesterase | other |
| UHGV-0017243_138 | UniRef90 | UniRef90_UPI0013D89F7D | metallophosphoesterase | NA |
| UHGV-0017243_138 | eggNOG-mapper | 697329.Rumal_1348 | Calcineurin-like phosphoesterase | NA |
| UHGV-0017243_138 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0017243_138 | COG | COG0639 | Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family | NA |
| UHGV-0017243_138 | Structural annotation | PF14582, MF_00905, TIGR03729, COG2129 | NA | NA |
| UHGV-0017243_145 | Structural annotation | COG4075 | NA | NA |
| UHGV-0017243_149 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |