| UHGV-0019966_3 | PHROG | phrog_35541 | NA | unknown function |
| UHGV-0019966_3 | eggNOG-mapper | 411470.RUMGNA_02068 | NA | NA |
| UHGV-0019966_4 | PHROG | phrog_35541 | NA | unknown function |
| UHGV-0019966_4 | UniRef90 | UniRef90_A0A3D6B2G4 | Mtd_N domain-containing protein | NA |
| UHGV-0019966_4 | eggNOG-mapper | 411470.RUMGNA_00120 | NA | NA |
| UHGV-0019966_8 | PHROG | phrog_32343 | NA | unknown function |
| UHGV-0019966_8 | Structural annotation | PF05113, NF033848, COG4379 | NA | NA |
| UHGV-0019966_9 | PHROG | phrog_30026 | NA | unknown function |
| UHGV-0019966_11 | KOfam | K20478 | GOLGB1; golgin subfamily B member 1 | NA |
| UHGV-0019966_11 | PHROG | phrog_4211 | tail length tape measure protein | tail |
| UHGV-0019966_11 | eggNOG-mapper | 1541960.KQ78_01861 | nuclear chromosome segregation | NA |
| UHGV-0019966_11 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0019966_11 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0019966_11 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0019966_14 | PHROG | phrog_2729 | virion structural protein | head and packaging |
| UHGV-0019966_14 | UniRef90 | UniRef90_V9VFQ8 | Putative structural protein | NA |
| UHGV-0019966_14 | eggNOG-mapper | 1308863.U5J9C4_9CAUD | NA | NA |
| UHGV-0019966_14 | Structural annotation | PF06488, TIGR01603 | NA | NA |
| UHGV-0019966_15 | PHROG | phrog_4051 | NA | unknown function |
| UHGV-0019966_16 | PHROG | phrog_6123 | virion structural protein | head and packaging |
| UHGV-0019966_16 | Structural annotation | PF06141 | NA | NA |
| UHGV-0019966_17 | PHROG | phrog_31155 | NA | unknown function |
| UHGV-0019966_17 | Structural annotation | PF19408, PF11649, NF041894, COG5614 | NA | NA |
| UHGV-0019966_18 | PHROG | phrog_29637 | NA | unknown function |
| UHGV-0019966_19 | PHROG | phrog_3853 | NA | unknown function |
| UHGV-0019966_21 | PHROG | phrog_4088 | NA | unknown function |
| UHGV-0019966_21 | eggNOG-mapper | 1541960.KQ78_01850 | NA | NA |
| UHGV-0019966_21 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0019966_23 | PHROG | phrog_3313 | NA | unknown function |
| UHGV-0019966_23 | eggNOG-mapper | 1304866.K413DRAFT_4735 | NA | NA |
| UHGV-0019966_23 | Structural annotation | PF09979, TIGR01543, COG3566 | NA | NA |
| UHGV-0019966_24 | PHROG | phrog_2739 | portal protein | head and packaging |
| UHGV-0019966_24 | UniRef90 | UniRef90_A0A345BPV2 | Putative portal protein | NA |
| UHGV-0019966_24 | eggNOG-mapper | 1582152.A0A0A8WIM8_9CAUD | NA | NA |
| UHGV-0019966_24 | Structural annotation | PF05133, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0019966_25 | PHROG | phrog_9084 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_25 | UniRef90 | UniRef90_A0A2I2L3U9 | Endonuclease | NA |
| UHGV-0019966_25 | eggNOG-mapper | 397291.C804_06294 | transposase activity | NA |
| UHGV-0019966_25 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-0019966_25 | Structural annotation | PF18741, MF_04160, NF007294, COG2852 | NA | NA |
| UHGV-0019966_27 | PHROG | phrog_24618 | NA | unknown function |
| UHGV-0019966_28 | eggNOG-mapper | 1308863.U5J9B2_9CAUD | NA | NA |
| UHGV-0019966_29 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_29 | UniRef90 | UniRef90_A0A481YSM9 | HNH endonuclease | NA |
| UHGV-0019966_29 | eggNOG-mapper | 1423814.HMPREF0549_1779 | NUMOD4 motif | NA |
| UHGV-0019966_29 | PADLOC | HEase_00016 | homing endonuclease | RM |
| UHGV-0019966_29 | Pfam | PF07463 | NUMOD4 motif | NUMOD4 |
| UHGV-0019966_29 | Pfam | PF13392 | HNH endonuclease | HNH_3 |
| UHGV-0019966_29 | Pfam | PF07453 | NUMOD1 domain | NUMOD1 |
| UHGV-0019966_29 | Structural annotation | PF07463, PF07453 | NA | NA |
| UHGV-0019966_30 | PHROG | phrog_15503 | NA | unknown function |
| UHGV-0019966_30 | eggNOG-mapper | 1560313.A0A0D3MT14_9CAUD | NA | NA |
| UHGV-0019966_30 | Structural annotation | PF05876, COG5410 | NA | NA |
| UHGV-0019966_31 | PHROG | phrog_3314 | NA | unknown function |
| UHGV-0019966_31 | eggNOG-mapper | 1308863.U5J9N3_9CAUD | NA | NA |
| UHGV-0019966_32 | PHROG | phrog_5767 | sigma factor | transcription regulation |
| UHGV-0019966_32 | UniRef90 | UniRef90_A0A345BPU6 | HTH DNA binding domain protein | NA |
| UHGV-0019966_32 | eggNOG-mapper | 1123239.KB898628_gene3218 | NA | NA |
| UHGV-0019966_43 | Structural annotation | PF06941, MF_01022, NF003937, COG4502 | NA | NA |
| UHGV-0019966_44 | Structural annotation | MF_00085, NF003076, COG0231 | NA | NA |
| UHGV-0019966_46 | PHROG | phrog_20187 | NA | unknown function |
| UHGV-0019966_46 | Structural annotation | PF21762, MF_00045, NF006316, COG0847 | NA | NA |
| UHGV-0019966_48 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |
| UHGV-0019966_51 | Structural annotation | PF00679, MF_01515, NF003194, COG4843 | NA | NA |
| UHGV-0019966_52 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |
| UHGV-0019966_54 | KOfam | K03698 | cbf, cbf1; 3'-5' exoribonuclease [EC:3.1.-.-] | NA |
| UHGV-0019966_54 | PHROG | phrog_5889 | NA | unknown function |
| UHGV-0019966_54 | UniRef90 | UniRef90_R5IXU6 | HD domain-containing protein | NA |
| UHGV-0019966_54 | eggNOG-mapper | 1280692.AUJL01000009_gene2990 | Metal dependent phosphohydrolases with conserved 'HD' motif. | NA |
| UHGV-0019966_54 | Pfam | PF01966 | HD domain | HD |
| UHGV-0019966_54 | Structural annotation | PF01966, MF_01427, NF010007, COG3481 | NA | NA |
| UHGV-0019966_58 | KOfam | K18555 | qnr, mcbG; fluoroquinolone resistance protein | NA |
| UHGV-0019966_58 | Pfam | PF00805 | Pentapeptide repeats (8 copies) | Pentapeptide |
| UHGV-0019966_58 | Pfam | PF13599 | Pentapeptide repeats (9 copies) | Pentapeptide_4 |
| UHGV-0019966_59 | KOfam | K18555 | qnr, mcbG; fluoroquinolone resistance protein | NA |
| UHGV-0019966_59 | Pfam | PF13599 | Pentapeptide repeats (9 copies) | Pentapeptide_4 |
| UHGV-0019966_60 | KOfam | K18555 | qnr, mcbG; fluoroquinolone resistance protein | NA |
| UHGV-0019966_60 | Pfam | PF13599 | Pentapeptide repeats (9 copies) | Pentapeptide_4 |
| UHGV-0019966_62 | PHROG | phrog_2319 | NA | unknown function |
| UHGV-0019966_62 | eggNOG-mapper | 1564096.A0A0A0YSP0_9CAUD | NA | NA |
| UHGV-0019966_62 | Structural annotation | PF17768, MF_01959, NF009635, COG0048 | NA | NA |
| UHGV-0019966_66 | eggNOG-mapper | 411467.BACCAP_03130 | NA | NA |
| UHGV-0019966_68 | Structural annotation | PF02581, MF_02232, TIGR01182, COG0135 | NA | NA |
| UHGV-0019966_69 | KOfam | K01258 | pepT; tripeptide aminopeptidase [EC:3.4.11.4] | NA |
| UHGV-0019966_69 | PHROG | phrog_34186 | NA | unknown function |
| UHGV-0019966_69 | UniRef90 | UniRef90_A0A843FCH3 | M28 family peptidase | NA |
| UHGV-0019966_69 | eggNOG-mapper | 935948.KE386495_gene2240 | Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls | NA |
| UHGV-0019966_69 | COG | COG0624 | Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase | NA |
| UHGV-0019966_69 | Structural annotation | PF05343, MF_01120, TIGR01883, COG1363 | NA | NA |
| UHGV-0019966_70 | PHROG | phrog_18912 | NA | unknown function |
| UHGV-0019966_70 | UniRef90 | UniRef90_A0A0B3BKP6 | LIM zinc-binding domain-containing protein | NA |
| UHGV-0019966_70 | eggNOG-mapper | 935948.KE386495_gene2241 | NA | NA |
| UHGV-0019966_72 | PHROG | phrog_5123 | homing endonuclease with GIY-YIG motif | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_72 | UniRef90 | UniRef90_A0A349YKA3 | GIY-YIG domain-containing protein | NA |
| UHGV-0019966_72 | eggNOG-mapper | 1126950.G9J202_9CAUD | nucleic acid binding | NA |
| UHGV-0019966_72 | PADLOC | HEase_00030 | homing endonuclease | RM |
| UHGV-0019966_72 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0019966_72 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0019966_72 | Structural annotation | PF19835, PF13518, PF07453, TIGR01453 | NA | NA |
| UHGV-0019966_73 | PHROG | phrog_850 | RNA-binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_73 | UniRef90 | UniRef90_A0A843GUP6 | NA | NA |
| UHGV-0019966_73 | eggNOG-mapper | 443254.Marpi_0401 | NA | NA |
| UHGV-0019966_73 | Pfam | PF11443 | NA | DUF2828 |
| UHGV-0019966_73 | COG | COG2304 | Secreted protein containing bacterial Ig-like domain and vWFA domain | NA |
| UHGV-0019966_73 | Structural annotation | PF11443, MF_01340, COG2304 | NA | NA |
| UHGV-0019966_74 | UniRef90 | UniRef90_UPI0006882B17 | C39 family peptidase | NA |
| UHGV-0019966_74 | eggNOG-mapper | 1410650.JHWL01000009_gene2005 | Peptidase_C39 like family | NA |
| UHGV-0019966_74 | Pfam | PF13529 | Peptidase_C39 like family | Peptidase_C39_2 |
| UHGV-0019966_74 | Structural annotation | PF05543, NF033920 | NA | NA |
| UHGV-0019966_75 | KOfam | K01371 | CTSK; cathepsin K [EC:3.4.22.38] | NA |
| UHGV-0019966_75 | PHROG | phrog_16701 | peptidase | other |
| UHGV-0019966_75 | UniRef90 | UniRef90_UPI001E2EF013 | C1 family peptidase | NA |
| UHGV-0019966_75 | eggNOG-mapper | 1123504.JQKD01000033_gene5256 | cysteine protease | NA |
| UHGV-0019966_75 | Pfam | PF00112 | Papain family cysteine protease | Peptidase_C1 |
| UHGV-0019966_75 | COG | COG4870 | Cysteine protease, C1A family | NA |
| UHGV-0019966_77 | PHROG | phrog_10292 | NA | unknown function |
| UHGV-0019966_77 | UniRef90 | UniRef90_G9RWB1 | TM2 domain-containing protein | NA |
| UHGV-0019966_77 | eggNOG-mapper | 665956.HMPREF1032_00562 | TM2 domain | NA |
| UHGV-0019966_77 | Pfam | PF13240 | zinc-ribbon domain | zinc_ribbon_2 |
| UHGV-0019966_77 | Pfam | PF05154 | TM2 domain | TM2 |
| UHGV-0019966_77 | COG | COG2314 | NA | NA |
| UHGV-0019966_77 | Structural annotation | PF05154, PF12773, MF_00788, NF003161 | NA | NA |
| UHGV-0019966_79 | Structural annotation | PF18414 | NA | NA |
| UHGV-0019966_85 | Structural annotation | PF14282 | NA | NA |
| UHGV-0019966_95 | KOfam | K06871 | NA | NA |
| UHGV-0019966_95 | Structural annotation | PF13353, MF_01225_A, NF040492, COG0535 | NA | NA |
| UHGV-0019966_96 | Structural annotation | MF_00660, TIGR04115, COG0535 | NA | NA |
| UHGV-0019966_98 | Structural annotation | PF20010 | NA | NA |
| UHGV-0019966_99 | eggNOG-mapper | 1233950.IW22_03440 | tail collar domain protein | NA |
| UHGV-0019966_99 | COG | COG4675 | Phage tail collar domain | NA |
| UHGV-0019966_100 | KOfam | K07074 | NA | NA |
| UHGV-0019966_100 | PHROG | phrog_388 | nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_100 | UniRef90 | UniRef90_A0A843FSU3 | Nucleotidyltransferase domain-containing protein | NA |
| UHGV-0019966_100 | eggNOG-mapper | 1236973.JCM9157_1946 | Predicted nucleotidyltransferase | NA |
| UHGV-0019966_100 | Structural annotation | PF10127, NF000079, COG3541 | NA | NA |
| UHGV-0019966_101 | PHROG | phrog_1649 | metallo-phosphoesterase | other |
| UHGV-0019966_101 | UniRef90 | UniRef90_A0A843FHD5 | Metallophosphoesterase | NA |
| UHGV-0019966_101 | eggNOG-mapper | 1120746.CCNL01000005_gene145 | Calcineurin-like phosphoesterase | NA |
| UHGV-0019966_101 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0019966_101 | COG | COG1408 | Predicted phosphohydrolase, MPP superfamily | NA |
| UHGV-0019966_101 | Structural annotation | PF14582, MF_00905, TIGR03729, COG2129 | NA | NA |
| UHGV-0019966_102 | KOfam | K00600 | glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] | NA |
| UHGV-0019966_102 | PHROG | phrog_9968 | methyltransferase | other |
| UHGV-0019966_102 | UniRef90 | UniRef90_A0A336N2U3 | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase | NA |
| UHGV-0019966_102 | eggNOG-mapper | 883109.HMPREF0380_01006 | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | NA |
| UHGV-0019966_102 | Pfam | PF00464 | Serine hydroxymethyltransferase | SHMT |
| UHGV-0019966_102 | COG | COG0112 | Glycine/serine hydroxymethyltransferase | NA |
| UHGV-0019966_103 | KOfam | K00600 | glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] | NA |
| UHGV-0019966_103 | PHROG | phrog_9968 | methyltransferase | other |
| UHGV-0019966_103 | UniRef90 | UniRef90_A0A1Q6QIL6 | Serine hydroxymethyltransferase | NA |
| UHGV-0019966_103 | eggNOG-mapper | 888727.HMPREF9092_1518 | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | NA |
| UHGV-0019966_103 | Pfam | PF00464 | Serine hydroxymethyltransferase | SHMT |
| UHGV-0019966_103 | COG | COG0112 | Glycine/serine hydroxymethyltransferase | NA |
| UHGV-0019966_108 | PHROG | phrog_968 | RNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_108 | UniRef90 | UniRef90_UPI00164D0579 | 2'-5' RNA ligase | NA |
| UHGV-0019966_108 | eggNOG-mapper | 247156.NFA_39550 | RNA ligase | NA |
| UHGV-0019966_108 | Structural annotation | PF09414, MF_04150, TIGR02306, COG1423 | NA | NA |
| UHGV-0019966_109 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-0019966_109 | Structural annotation | PF19789 | NA | NA |
| UHGV-0019966_110 | KOfam | K07313 | pphA; serine/threonine protein phosphatase 1 [EC:3.1.3.16] | NA |
| UHGV-0019966_110 | PHROG | phrog_246 | NinI-like serine-threonine phosphatase | other |
| UHGV-0019966_110 | UniRef90 | UniRef90_A0A328PQ69 | Metallophosphoesterase | NA |
| UHGV-0019966_110 | eggNOG-mapper | 443254.Marpi_1098 | PFAM metallophosphoesterase | NA |
| UHGV-0019966_110 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0019966_110 | COG | COG0639 | Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family | NA |
| UHGV-0019966_110 | Structural annotation | PF12850, MF_01443, NF007425, COG0622 | NA | NA |
| UHGV-0019966_111 | PHROG | phrog_6931 | NA | unknown function |
| UHGV-0019966_111 | UniRef90 | UniRef90_A0A345BPY6 | AAA domain protein | NA |
| UHGV-0019966_111 | eggNOG-mapper | 273068.TTE0679 | Chromatin associated protein KTI12 | NA |
| UHGV-0019966_111 | Pfam | PF13671 | AAA domain | AAA_33 |
| UHGV-0019966_111 | COG | COG4639 | Predicted kinase | NA |
| UHGV-0019966_111 | Structural annotation | PF13671, MF_00065, TIGR03574, COG4088 | NA | NA |
| UHGV-0019966_112 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-0019966_112 | UniRef90 | UniRef90_A0A1I0M725 | Calcineurin-like phosphoesterase superfamily protein | NA |
| UHGV-0019966_112 | eggNOG-mapper | 1392491.JIAE01000001_gene1129 | Calcineurin-like phosphoesterase | NA |
| UHGV-0019966_112 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0019966_112 | COG | COG4186 | NA | NA |
| UHGV-0019966_112 | Structural annotation | NF006988, COG4186 | NA | NA |
| UHGV-0019966_114 | PHROG | phrog_13126 | beta-1,4-glycosyltransferase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0019966_114 | UniRef90 | UniRef90_UPI0013799F0A | glycosyltransferase | NA |
| UHGV-0019966_114 | eggNOG-mapper | 610130.Closa_3579 | Glycosyl transferase, family 2 | NA |
| UHGV-0019966_114 | Pfam | PF00535 | Glycosyl transferase family 2 | Glycos_transf_2 |
| UHGV-0019966_114 | COG | COG0463 | Glycosyltransferase involved in cell wall bisynthesis | NA |
| UHGV-0019966_114 | Structural annotation | PF18768, PF13641, MF_00994, MF_00316, TIGR04195, COG0457, COG0463 | NA | NA |
| UHGV-0019966_116 | Structural annotation | PF13876, NF011863 | NA | NA |
| UHGV-0019966_118 | KOfam | K03469 | rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4] | NA |
| UHGV-0019966_118 | PHROG | phrog_531 | Rnase H | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_118 | UniRef90 | UniRef90_A0A843FJ64 | Ribonuclease H | NA |
| UHGV-0019966_118 | eggNOG-mapper | 656519.Halsa_1618 | Endonuclease that specifically degrades the RNA of RNA- DNA hybrids | NA |
| UHGV-0019966_118 | Pfam | PF00075 | RNase H | RNase_H |
| UHGV-0019966_118 | COG | COG0328 | Ribonuclease HI | NA |
| UHGV-0019966_118 | Structural annotation | PF00075, MF_00042, NF001236, COG0328 | NA | NA |
| UHGV-0019966_119 | KOfam | K02470 | gyrB; DNA gyrase subunit B [EC:5.6.2.2] | NA |
| UHGV-0019966_119 | PHROG | phrog_543 | DNA topoisomerase II large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_119 | UniRef90 | UniRef90_A0A345BPY9 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0019966_119 | eggNOG-mapper | 1236973.JCM9157_1456 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0019966_119 | Pfam | PF02518 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | HATPase_c |
| UHGV-0019966_119 | Pfam | PF00204 | DNA gyrase B | DNA_gyraseB |
| UHGV-0019966_119 | Pfam | PF01751 | Toprim domain | Toprim |
| UHGV-0019966_119 | COG | COG0187 | DNA gyrase/topoisomerase IV, subunit B | NA |
| UHGV-0019966_119 | Structural annotation | PF00204, MF_01898, NF004189, COG0187 | NA | NA |
| UHGV-0019966_120 | KOfam | K02470 | gyrB; DNA gyrase subunit B [EC:5.6.2.2] | NA |
| UHGV-0019966_120 | PHROG | phrog_543 | DNA topoisomerase II large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_120 | UniRef90 | UniRef90_A0A832SWV5 | DNA topoisomerase IV subunit B | NA |
| UHGV-0019966_120 | eggNOG-mapper | 1410616.JHXE01000007_gene1913 | TopoisomeraseII | NA |
| UHGV-0019966_120 | Pfam | PF00986 | DNA gyrase B subunit, carboxyl terminus | DNA_gyraseB_C |
| UHGV-0019966_120 | COG | COG0187 | DNA gyrase/topoisomerase IV, subunit B | NA |
| UHGV-0019966_120 | Structural annotation | PF00986 | NA | NA |
| UHGV-0019966_121 | KOfam | K02469 | gyrA; DNA gyrase subunit A [EC:5.6.2.2] | NA |
| UHGV-0019966_121 | PHROG | phrog_551 | DNA topoisomerase II | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_121 | UniRef90 | UniRef90_A0A832SNJ2 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0019966_121 | eggNOG-mapper | 398512.JQKC01000021_gene3650 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0019966_121 | Pfam | PF00521 | DNA gyrase/topoisomerase IV, subunit A | DNA_topoisoIV |
| UHGV-0019966_121 | Pfam | PF03989 | DNA gyrase C-terminal domain, beta-propeller | DNA_gyraseA_C |
| UHGV-0019966_121 | COG | COG0188 | DNA gyrase/topoisomerase IV, subunit A | NA |
| UHGV-0019966_121 | Structural annotation | PF00521, PF03989, MF_01897, NF004043, COG0188 | NA | NA |
| UHGV-0019966_123 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-0019966_123 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_123 | UniRef90 | UniRef90_A0A843FST5 | DNA ligase | NA |
| UHGV-0019966_123 | eggNOG-mapper | 411470.RUMGNA_00017 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-0019966_123 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-0019966_123 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-0019966_123 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-0019966_123 | NCBIFam | NF005932.1 | NAD-dependent DNA ligase LigA | NA |
| UHGV-0019966_123 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0019966_123 | HAMAP | MF_01588 | DNA ligase [ligA] | NA |
| UHGV-0019966_123 | Structural annotation | PF01653, PF03120, PF00533, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-0019966_125 | PHROG | phrog_559 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_125 | UniRef90 | UniRef90_UPI000FF8D02D | AP2 domain-containing protein | NA |
| UHGV-0019966_125 | eggNOG-mapper | 1460640.JCM19046_3498 | NA | NA |
| UHGV-0019966_125 | Structural annotation | PF21598, TIGR00632, COG3727 | NA | NA |
| UHGV-0019966_126 | UniRef90 | UniRef90_A0A345BPT3 | SarR-like protein | NA |
| UHGV-0019966_126 | Structural annotation | PF04182, MF_01909, NF040939, COG1675 | NA | NA |
| UHGV-0019966_127 | PHROG | phrog_314 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_127 | eggNOG-mapper | 476272.RUMHYD_01972 | GIY-YIG type nucleases (URI domain) | NA |
| UHGV-0019966_127 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0019966_127 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0019966_127 | COG | COG3860 | NA | NA |
| UHGV-0019966_127 | Structural annotation | PF19835, TIGR01453 | NA | NA |
| UHGV-0019966_129 | PHROG | phrog_6721 | NA | unknown function |
| UHGV-0019966_129 | eggNOG-mapper | 1235802.C823_04642 | NA | NA |
| UHGV-0019966_130 | PHROG | phrog_559 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_130 | UniRef90 | UniRef90_A0A2G2M2K8 | AP2 domain-containing protein | NA |
| UHGV-0019966_130 | eggNOG-mapper | 1235799.C818_03921 | NA | NA |
| UHGV-0019966_130 | Structural annotation | PF21598, PF18337, TIGR00632, COG3727 | NA | NA |
| UHGV-0019966_131 | PHROG | phrog_6721 | NA | unknown function |
| UHGV-0019966_131 | eggNOG-mapper | 1235802.C823_04642 | NA | NA |
| UHGV-0019966_132 | UniRef90 | UniRef90_A0A843FPF0 | Winged helix-turn-helix domain-containing protein | NA |
| UHGV-0019966_132 | Pfam | PF13463 | Winged helix DNA-binding domain | HTH_27 |
| UHGV-0019966_132 | Structural annotation | PF03444, MF_00732, TIGR02337, COG1321 | NA | NA |
| UHGV-0019966_133 | Structural annotation | PF00436, PF19649, MF_00984, NF004476, COG2965 | NA | NA |
| UHGV-0019966_134 | PHROG | phrog_124 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_134 | UniRef90 | UniRef90_A0A843GMB3 | ATP-binding protein | NA |
| UHGV-0019966_134 | eggNOG-mapper | 1541960.KQ78_01919 | Belongs to the helicase family. UvrD subfamily | NA |
| UHGV-0019966_134 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-0019966_134 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-0019966_134 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-0019966_136 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0019966_136 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_136 | UniRef90 | UniRef90_A0A843FVR3 | DNA helicase | NA |
| UHGV-0019966_136 | eggNOG-mapper | 224308.BSU20370 | DnaB-like helicase C terminal domain | NA |
| UHGV-0019966_136 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-0019966_136 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0019966_136 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0019966_136 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0019966_137 | PHROG | phrog_4645 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_137 | UniRef90 | UniRef90_A0A226QQB9 | DOD-type homing endonuclease domain-containing protein | NA |
| UHGV-0019966_137 | eggNOG-mapper | 760568.Desku_1111 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-0019966_137 | Pfam | PF14528 | LAGLIDADG-like domain | LAGLIDADG_3 |
| UHGV-0019966_137 | COG | COG1372 | Intein/homing endonuclease | NA |
| UHGV-0019966_137 | Structural annotation | PF03161, PF02796, MF_01420, TIGR00647, TIGR04381, COG1372 | NA | NA |
| UHGV-0019966_139 | PHROG | phrog_47 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_139 | UniRef90 | UniRef90_A0A345BPU0 | DNA primase | NA |
| UHGV-0019966_139 | eggNOG-mapper | 224308.BSU20360 | DNA primase activity | NA |
| UHGV-0019966_139 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0019966_139 | Structural annotation | PF19898, PF01807, MF_00974, NF006382, COG0358 | NA | NA |
| UHGV-0019966_140 | PHROG | phrog_7168 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_140 | UniRef90 | UniRef90_A0A249Y1D2 | GIY-YIG domain-containing protein | NA |
| UHGV-0019966_140 | eggNOG-mapper | 702450.CUW_1847 | GIY-YIG catalytic domain | NA |
| UHGV-0019966_140 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0019966_141 | PHROG | phrog_33561 | NA | unknown function |
| UHGV-0019966_141 | eggNOG-mapper | 1500386.A0A060AFI7_9CAUD | DNA primase activity | NA |
| UHGV-0019966_141 | Structural annotation | PF13155, MF_00017, TIGR00646, COG0353 | NA | NA |
| UHGV-0019966_142 | KOfam | K07462 | recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] | NA |
| UHGV-0019966_142 | PHROG | phrog_2484 | RecJ-like ssDNA exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_142 | UniRef90 | UniRef90_A0A843FU26 | DHH family phosphoesterase | NA |
| UHGV-0019966_142 | eggNOG-mapper | 665956.HMPREF1032_03163 | exonuclease | NA |
| UHGV-0019966_142 | Pfam | PF01368 | DHH family | DHH |
| UHGV-0019966_142 | Pfam | PF17768 | RecJ OB domain | RecJ_OB |
| UHGV-0019966_142 | COG | COG0608 | ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation | NA |
| UHGV-0019966_142 | Structural annotation | PF17768, PF02272, MF_00207, TIGR00644, COG0608 | NA | NA |
| UHGV-0019966_145 | PHROG | phrog_559 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_145 | UniRef90 | UniRef90_A0A223LDQ7 | Homing endonuclease | NA |
| UHGV-0019966_145 | eggNOG-mapper | 881953.E0YIZ1_9CAUD | HNH endonuclease | NA |
| UHGV-0019966_145 | Structural annotation | PF04480, PF05265, TIGR00632, COG3727 | NA | NA |
| UHGV-0019966_146 | KOfam | K03581 | recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] | NA |
| UHGV-0019966_146 | PHROG | phrog_325 | Dda-like helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_146 | UniRef90 | UniRef90_A0A843FIT8 | ATP-binding domain-containing protein | NA |
| UHGV-0019966_146 | eggNOG-mapper | 1122132.AQYH01000018_gene1160 | ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member | NA |
| UHGV-0019966_146 | Pfam | PF13538 | UvrD-like helicase C-terminal domain | UvrD_C_2 |
| UHGV-0019966_146 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0019966_146 | Structural annotation | MF_03176, TIGR01447 | NA | NA |
| UHGV-0019966_148 | Structural annotation | COG3189 | NA | NA |
| UHGV-0019966_149 | KOfam | K02337 | dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] | NA |
| UHGV-0019966_149 | PHROG | phrog_405 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_149 | UniRef90 | UniRef90_A0A858MXR6 | DNA-directed DNA polymerase | NA |
| UHGV-0019966_149 | eggNOG-mapper | 742735.HMPREF9467_00895 | DNA polymerase III alpha subunit | NA |
| UHGV-0019966_149 | Pfam | PF02811 | PHP domain | PHP |
| UHGV-0019966_149 | Pfam | PF07733 | Bacterial DNA polymerase III alpha NTPase domain | DNA_pol3_alpha |
| UHGV-0019966_149 | Pfam | PF17657 | Bacterial DNA polymerase III alpha subunit finger domain | DNA_pol3_finger |
| UHGV-0019966_149 | Pfam | PF14579 | Helix-hairpin-helix motif | HHH_6 |
| UHGV-0019966_149 | NCBIFam | TIGR00594.1 | DNA polymerase III subunit alpha | NA |
| UHGV-0019966_149 | COG | COG0587 | DNA polymerase III, alpha subunit | NA |
| UHGV-0019966_149 | Structural annotation | PF07733, PF02811, PF17657, PF14579, MF_01902, NF005617, COG0587 | NA | NA |
| UHGV-0019966_150 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-0019966_150 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-0019966_150 | UniRef90 | UniRef90_A0A843FCP8 | Guanylate kinase-like domain-containing protein | NA |
| UHGV-0019966_150 | eggNOG-mapper | 545243.BAEV01000132_gene3477 | Guanylate kinase | NA |
| UHGV-0019966_150 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-0019966_150 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-0019966_150 | Structural annotation | PF00625, MF_00328, NF011324, COG0194 | NA | NA |
| UHGV-0019966_151 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-0019966_151 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-0019966_151 | UniRef90 | UniRef90_R7F5N5 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0019966_151 | eggNOG-mapper | 500635.MITSMUL_03099 | Ribonucleoside-triphosphate reductase | NA |
| UHGV-0019966_151 | Pfam | PF03477 | ATP cone domain | ATP-cone |
| UHGV-0019966_151 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-0019966_151 | NCBIFam | NF006732.0 | anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0019966_151 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0019966_151 | Structural annotation | PF13597, PF03477, MF_00440, MF_02058, NF006732, COG1328 | NA | NA |
| UHGV-0019966_152 | Structural annotation | PF20010 | NA | NA |
| UHGV-0019966_154 | Structural annotation | PF10750, MF_01122, TIGR00285, COG1581 | NA | NA |
| UHGV-0019966_155 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-0019966_155 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_155 | UniRef90 | UniRef90_A0A843FKH7 | dUTPase domain-containing protein (Fragment) | NA |
| UHGV-0019966_155 | eggNOG-mapper | 1158607.UAU_01270 | dUTPase | NA |
| UHGV-0019966_155 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-0019966_155 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-0019966_155 | Structural annotation | PF00692, MF_00116, NF010561, COG0756 | NA | NA |
| UHGV-0019966_156 | KOfam | K01159 | ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] | NA |
| UHGV-0019966_156 | PHROG | phrog_827 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0019966_156 | UniRef90 | UniRef90_A0A349YPC6 | Crossover junction endodeoxyribonuclease RuvC | NA |
| UHGV-0019966_156 | Pfam | PF02075 | Crossover junction endodeoxyribonuclease RuvC | RuvC |
| UHGV-0019966_156 | COG | COG0817 | Holliday junction resolvasome RuvABC endonuclease subunit RuvC | NA |
| UHGV-0019966_156 | Structural annotation | PF07066, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-0019966_159 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-0019966_159 | UniRef90 | UniRef90_A0A345BPX4 | Carbohydrate binding domain/collagen triple helix repeat protein | NA |
| UHGV-0019966_159 | eggNOG-mapper | 1226322.HMPREF1545_00077 | NA | NA |
| UHGV-0019966_159 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-0019966_160 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0019966_160 | eggNOG-mapper | 641112.ACOK01000103_gene525 | NA | NA |
| UHGV-0019966_161 | eggNOG-mapper | 658655.HMPREF0988_00918 | NA | NA |
| UHGV-0019966_162 | eggNOG-mapper | 1408437.JNJN01000043_gene805 | NA | NA |
| UHGV-0019966_163 | KOfam | K11641 | natR; two-component system, LytTR family, response regulator NatR | NA |
| UHGV-0019966_163 | PHROG | phrog_8810 | NA | unknown function |
| UHGV-0019966_163 | Pfam | PF04397 | LytTr DNA-binding domain | LytTR |
| UHGV-0019966_163 | COG | COG3279 | DNA-binding response regulator, LytR/AlgR family | NA |
| UHGV-0019966_164 | PHROG | phrog_13712 | holin | lysis |
| UHGV-0019966_164 | UniRef90 | UniRef90_A0A2P8EL22 | Superfamily 6 holin (LLH) | NA |
| UHGV-0019966_164 | eggNOG-mapper | 796940.HMPREF9628_01284 | NA | NA |
| UHGV-0019966_165 | PHROG | phrog_6320 | tail fiber protein | tail |
| UHGV-0019966_165 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0019966_166 | eggNOG-mapper | 1123508.JH636444_gene5347 | NA | NA |
| UHGV-0019966_169 | eggNOG-mapper | 657322.FPR_22010 | NA | NA |
| UHGV-0019966_169 | Structural annotation | PF10651 | NA | NA |
| UHGV-0019966_170 | eggNOG-mapper | 1304866.K413DRAFT_4770 | PFAM Formylglycine-generating sulfatase enzyme | NA |
| UHGV-0019966_170 | COG | COG1262 | Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain | NA |
| UHGV-0019966_170 | Structural annotation | PF10651, NF041431, COG3401 | NA | NA |
| UHGV-0019966_172 | PHROG | phrog_14959 | NA | unknown function |
| UHGV-0019966_172 | eggNOG-mapper | 762968.HMPREF9441_03606 | NA | NA |