| UHGV-0024388_1 | KOfam | K14059 | int; integrase | NA |
| UHGV-0024388_1 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0024388_1 | UniRef90 | UniRef90_A0A3D2G173 | Tyr recombinase domain-containing protein | NA |
| UHGV-0024388_1 | eggNOG-mapper | 641112.ACOK01000111_gene1860 | Phage integrase family | NA |
| UHGV-0024388_1 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0024388_1 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0024388_1 | Structural annotation | PF00589, PF12167, MF_02055, NF040815, COG4974 | NA | NA |
| UHGV-0024388_2 | eggNOG-mapper | 1382304.JNIL01000001_gene3508 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0024388_2 | COG | COG3620 | Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) | NA |
| UHGV-0024388_2 | Structural annotation | PF12844, MF_00535, NF041951, COG3655 | NA | NA |
| UHGV-0024388_3 | PHROG | phrog_33519 | NA | unknown function |
| UHGV-0024388_3 | eggNOG-mapper | 1507.HMPREF0262_01197 | NA | NA |
| UHGV-0024388_3 | Structural annotation | PF13958, NF010262, COG2337 | NA | NA |
| UHGV-0024388_5 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0024388_5 | UniRef90 | UniRef90_A0A374HKJ0 | XRE family transcriptional regulator | NA |
| UHGV-0024388_5 | eggNOG-mapper | 97138.C820_00203 | Transcriptional | NA |
| UHGV-0024388_5 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0024388_5 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0024388_5 | Structural annotation | PF12844, MF_00535, NF007257, COG1396 | NA | NA |
| UHGV-0024388_7 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0024388_7 | PHROG | phrog_63 | anti-repressor Ant | transcription regulation |
| UHGV-0024388_7 | UniRef90 | UniRef90_A0A1C6EMR2 | Phage anti-repressor protein | NA |
| UHGV-0024388_7 | eggNOG-mapper | 1123263.AUKY01000076_gene1778 | Phage antirepressor protein | NA |
| UHGV-0024388_7 | Pfam | PF08346 | AntA/AntB antirepressor | AntA |
| UHGV-0024388_7 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0024388_7 | COG | COG3561 | Phage anti-repressor protein Ant | NA |
| UHGV-0024388_7 | Structural annotation | PF03374, PF08346, TIGR02681, COG3645, COG3561 | NA | NA |
| UHGV-0024388_17 | PHROG | phrog_3657 | NA | unknown function |
| UHGV-0024388_17 | eggNOG-mapper | 580332.Slit_1947 | NA | NA |
| UHGV-0024388_18 | PHROG | phrog_1227 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_18 | UniRef90 | UniRef90_A0A1Y3RPZ6 | NA | NA |
| UHGV-0024388_18 | eggNOG-mapper | 1158602.I590_00670 | NA | NA |
| UHGV-0024388_18 | Pfam | PF12684 | NA | DUF3799 |
| UHGV-0024388_18 | COG | COG1074 | 3'-5' helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0024388_18 | Structural annotation | PF12684, TIGR01896, COG4343 | NA | NA |
| UHGV-0024388_19 | eggNOG-mapper | 1235798.C817_04575 | NA | NA |
| UHGV-0024388_19 | Structural annotation | PF19561 | NA | NA |
| UHGV-0024388_20 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0024388_20 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_20 | UniRef90 | UniRef90_A0A3D1LE19 | Single-stranded DNA-binding protein | NA |
| UHGV-0024388_20 | eggNOG-mapper | 693746.OBV_12860 | Single-strand binding protein family | NA |
| UHGV-0024388_20 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0024388_20 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0024388_20 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0024388_20 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0024388_20 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0024388_21 | PHROG | phrog_8489 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_21 | eggNOG-mapper | 931626.Awo_c31180 | DnaD domain protein | NA |
| UHGV-0024388_21 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-0024388_21 | Structural annotation | PF09681, TIGR01714 | NA | NA |
| UHGV-0024388_22 | PHROG | phrog_11233 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_22 | UniRef90 | UniRef90_UPI0013D0F24F | conjugal transfer protein | NA |
| UHGV-0024388_22 | eggNOG-mapper | 388739.RSK20926_07818 | NA | NA |
| UHGV-0024388_22 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-0024388_22 | Structural annotation | PF13463, MF_01819, NF038251, COG1846 | NA | NA |
| UHGV-0024388_23 | PHROG | phrog_270 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_23 | UniRef90 | UniRef90_A0A1X7KK97 | Helix-turn-helix domain-containing protein | NA |
| UHGV-0024388_23 | eggNOG-mapper | 616991.JPOO01000003_gene2463 | Helix-turn-helix domain | NA |
| UHGV-0024388_23 | Pfam | PF13730 | Helix-turn-helix domain | HTH_36 |
| UHGV-0024388_24 | KOfam | K02315 | dnaC; DNA replication protein DnaC | NA |
| UHGV-0024388_24 | PHROG | phrog_5968 | replisome organizer | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_24 | UniRef90 | UniRef90_UPI0013D3F9A2 | phage replisome organizer N-terminal domain-containing protein | NA |
| UHGV-0024388_24 | eggNOG-mapper | 1282664.H354_00255 | N-terminal phage replisome organiser (Phage_rep_org_N) | NA |
| UHGV-0024388_24 | Pfam | PF09681 | N-terminal phage replisome organiser (Phage_rep_org_N) | Phage_rep_org_N |
| UHGV-0024388_24 | NCBIFam | TIGR01714.1 | phage replisome organizer, putative, N-terminal region | NA |
| UHGV-0024388_24 | Structural annotation | PF09681, TIGR01714, COG3756 | NA | NA |
| UHGV-0024388_25 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0024388_25 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_25 | UniRef90 | UniRef90_A0A2V2CUP5 | DNA helicase | NA |
| UHGV-0024388_25 | eggNOG-mapper | 1507.HMPREF0262_02683 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-0024388_25 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-0024388_25 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0024388_25 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0024388_25 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0024388_28 | PHROG | phrog_18716 | NA | unknown function |
| UHGV-0024388_28 | UniRef90 | UniRef90_A0A372V803 | NA | NA |
| UHGV-0024388_28 | eggNOG-mapper | 1029718.SFBM_0379 | NA | NA |
| UHGV-0024388_28 | Pfam | PF18909 | dATP/dGTP diphosphohydrolase, N-terminal | dGTP_diPhyd_N |
| UHGV-0024388_28 | Structural annotation | PF18909 | NA | NA |
| UHGV-0024388_29 | UniRef90 | UniRef90_UPI0019D1E2CF | FAD-dependent thymidylate synthase | NA |
| UHGV-0024388_29 | eggNOG-mapper | 1410632.JHWW01000006_gene695 | NA | NA |
| UHGV-0024388_29 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0024388_29 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0024388_30 | PHROG | phrog_190 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_30 | UniRef90 | UniRef90_A0A845R8D4 | NA | NA |
| UHGV-0024388_30 | Pfam | PF06356 | NA | DUF1064 |
| UHGV-0024388_30 | Structural annotation | PF06356, NF033179 | NA | NA |
| UHGV-0024388_32 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-0024388_32 | eggNOG-mapper | 881953.E0YJ34_9CAUD | NA | NA |
| UHGV-0024388_32 | Structural annotation | PF04466, PF17289, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0024388_34 | PHROG | phrog_2739 | portal protein | head and packaging |
| UHGV-0024388_34 | Structural annotation | PF07230, MF_04120, TIGR01539, COG5511 | NA | NA |
| UHGV-0024388_36 | Structural annotation | PF00210, MF_01441, NF011597, COG1528 | NA | NA |
| UHGV-0024388_37 | PHROG | phrog_3313 | NA | unknown function |
| UHGV-0024388_37 | Structural annotation | PF09979, TIGR01543, COG3740 | NA | NA |
| UHGV-0024388_39 | Structural annotation | PF03864, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0024388_41 | PHROG | phrog_4105 | NA | unknown function |
| UHGV-0024388_43 | Structural annotation | TIGR02215 | NA | NA |
| UHGV-0024388_44 | PHROG | phrog_16444 | NA | unknown function |
| UHGV-0024388_44 | eggNOG-mapper | 646529.Desaci_2033 | PFAM Ig domain protein, group 2 domain protein | NA |
| UHGV-0024388_44 | Pfam | PF02368 | Bacterial Ig-like domain (group 2) | Big_2 |
| UHGV-0024388_44 | COG | COG5492 | NA | NA |
| UHGV-0024388_44 | Structural annotation | PF02368, PF18957, MF_04116, NF040788, COG3291, COG5614 | NA | NA |
| UHGV-0024388_49 | Structural annotation | PF06488, PF02368, TIGR01603, COG5492 | NA | NA |
| UHGV-0024388_51 | KOfam | K10402 | KIF20; kinesin family member 20 | NA |
| UHGV-0024388_51 | PHROG | phrog_4211 | tail length tape measure protein | tail |
| UHGV-0024388_51 | UniRef90 | UniRef90_A0A2V2CTR2 | Phage tail tape measure protein | NA |
| UHGV-0024388_51 | eggNOG-mapper | 397290.C810_01746 | Phage-related minor tail protein | NA |
| UHGV-0024388_51 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0024388_51 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0024388_51 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0024388_51 | Structural annotation | PF10145, TIGR01760 | NA | NA |
| UHGV-0024388_52 | Structural annotation | PF05606, MF_00075, TIGR00008, COG0361 | NA | NA |
| UHGV-0024388_53 | Structural annotation | PF06995, PF02010, MF_04116, NF010681, COG3499 | NA | NA |
| UHGV-0024388_54 | PHROG | phrog_1887 | tail protein | tail |
| UHGV-0024388_54 | Structural annotation | PF14594, NF033848, COG3500 | NA | NA |
| UHGV-0024388_55 | Structural annotation | PF19079, TIGR04203 | NA | NA |
| UHGV-0024388_56 | Pfam | PF21722 | Glycine-rich domain | Gly_rich_2 |
| UHGV-0024388_56 | Structural annotation | PF14686, TIGR03000, COG2512 | NA | NA |
| UHGV-0024388_60 | PHROG | phrog_20388 | endolysin | lysis |
| UHGV-0024388_60 | UniRef90 | UniRef90_A0A350TI51 | LysM domain-containing protein | NA |
| UHGV-0024388_60 | eggNOG-mapper | 552398.HMPREF0866_03091 | CHAP domain | NA |
| UHGV-0024388_60 | Pfam | PF18013 | Phage tail lysozyme | Phage_lysozyme2 |
| UHGV-0024388_60 | Pfam | PF05257 | CHAP domain | CHAP |
| UHGV-0024388_60 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0024388_60 | COG | COG0791 | Cell wall-associated hydrolase, NlpC_P60 family | NA |
| UHGV-0024388_60 | Structural annotation | PF18013, PF01471, COG3409 | NA | NA |
| UHGV-0024388_61 | UniRef90 | UniRef90_A0A174XWS3 | Bacterial regulatory proteins, luxR family | NA |
| UHGV-0024388_61 | eggNOG-mapper | 485916.Dtox_2202 | Plasmid pRiA4b ORF-3-like protein | NA |
| UHGV-0024388_61 | Pfam | PF13384 | Homeodomain-like domain | HTH_23 |
| UHGV-0024388_61 | Pfam | PF08281 | Sigma-70, region 4 | Sigma70_r4_2 |
| UHGV-0024388_61 | Structural annotation | PF00196, NF040595, COG2771 | NA | NA |
| UHGV-0024388_62 | KOfam | K04763 | xerD; integrase/recombinase XerD | NA |
| UHGV-0024388_62 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0024388_62 | UniRef90 | UniRef90_G9YP38 | Site-specific recombinase, phage integrase family | NA |
| UHGV-0024388_62 | eggNOG-mapper | 435830.HMPREF0045_00394 | Belongs to the 'phage' integrase family. XerC subfamily | NA |
| UHGV-0024388_62 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0024388_62 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-0024388_62 | Structural annotation | PF00589, PF02899, MF_01808, TIGR02225, COG4974 | NA | NA |
| UHGV-0024388_63 | Structural annotation | PF05534, COG4877 | NA | NA |
| UHGV-0024388_65 | PHROG | phrog_4980 | superinfection exclusion | moron, auxiliary metabolic gene and host takeover |
| UHGV-0024388_65 | eggNOG-mapper | 1408324.JNJK01000013_gene73 | Host cell surface-exposed lipoprotein | NA |
| UHGV-0024388_65 | Pfam | PF07553 | Host cell surface-exposed lipoprotein | Lipoprotein_Ltp |
| UHGV-0024388_65 | COG | COG3064 | Membrane protein TolA involved in colicin uptake | NA |
| UHGV-0024388_66 | eggNOG-mapper | 742722.HMPREF9463_00436 | NA | NA |
| UHGV-0024388_67 | Structural annotation | COG2157 | NA | NA |
| UHGV-0024388_68 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0024388_68 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_68 | UniRef90 | UniRef90_A0A2M6WDQ8 | Single-stranded DNA-binding protein | NA |
| UHGV-0024388_68 | eggNOG-mapper | 688269.Theth_1460 | Single-stranded DNA-binding protein | NA |
| UHGV-0024388_68 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0024388_68 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0024388_68 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0024388_72 | UniRef90 | UniRef90_A0A416VIT4 | XRE family transcriptional regulator | NA |
| UHGV-0024388_72 | eggNOG-mapper | 1408437.JNJN01000040_gene204 | NA | NA |
| UHGV-0024388_72 | Pfam | PF07022 | Bacteriophage CI repressor helix-turn-helix domain | Phage_CI_repr |
| UHGV-0024388_72 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-0024388_73 | PHROG | phrog_2118 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024388_73 | UniRef90 | UniRef90_A0A417HX51 | HNH endonuclease | NA |
| UHGV-0024388_73 | eggNOG-mapper | 742740.HMPREF9474_03129 | HNH endonuclease | NA |
| UHGV-0024388_73 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0024388_73 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0024388_73 | Structural annotation | TIGR02646, COG1403 | NA | NA |
| UHGV-0024388_74 | Structural annotation | PF14354, NF007260 | NA | NA |
| UHGV-0024388_76 | KOfam | K05840 | DRD5; dopamine receptor D5 | NA |
| UHGV-0024388_76 | PHROG | phrog_15773 | NA | unknown function |
| UHGV-0024388_76 | dbAPIS | APIS008 | Alphafold2 predicted that Gad2 is an enzyme with a nucleotidyltransferase protein domain, suggesting that it inhibits Gabija via a mechanism of action different than Gad1. | NA |