| UHGV-0036558_1 | KOfam | K20478 | GOLGB1; golgin subfamily B member 1 | NA |
| UHGV-0036558_1 | PHROG | phrog_4211 | tail length tape measure protein | tail |
| UHGV-0036558_1 | UniRef90 | UniRef90_A0A843GPK6 | Phage tail tape measure protein | NA |
| UHGV-0036558_1 | eggNOG-mapper | 1610833.A0A0E3T6B7_9CAUD | peptidoglycan catabolic process | NA |
| UHGV-0036558_1 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0036558_1 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0036558_2 | PHROG | phrog_30570 | NA | unknown function |
| UHGV-0036558_4 | PHROG | phrog_2729 | virion structural protein | head and packaging |
| UHGV-0036558_4 | eggNOG-mapper | 1163671.JAGI01000002_gene1222 | NA | NA |
| UHGV-0036558_5 | PHROG | phrog_4051 | NA | unknown function |
| UHGV-0036558_6 | PHROG | phrog_6123 | virion structural protein | head and packaging |
| UHGV-0036558_6 | Structural annotation | PF06141 | NA | NA |
| UHGV-0036558_7 | UniRef90 | UniRef90_A0A345BPV9 | Ig domain protein | NA |
| UHGV-0036558_7 | Structural annotation | PF19408, PF11649, NF041894, COG5614 | NA | NA |
| UHGV-0036558_8 | PHROG | phrog_29637 | NA | unknown function |
| UHGV-0036558_8 | Structural annotation | PF14276 | NA | NA |
| UHGV-0036558_9 | PHROG | phrog_3853 | NA | unknown function |
| UHGV-0036558_9 | eggNOG-mapper | 1280.SAXN108_2264 | NA | NA |
| UHGV-0036558_10 | PHROG | phrog_30998 | NA | unknown function |
| UHGV-0036558_11 | PHROG | phrog_4088 | NA | unknown function |
| UHGV-0036558_11 | eggNOG-mapper | 1541960.KQ78_01850 | NA | NA |
| UHGV-0036558_11 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0036558_13 | PHROG | phrog_3313 | NA | unknown function |
| UHGV-0036558_13 | UniRef90 | UniRef90_A0A7S6RBM7 | Putative prohead protease | NA |
| UHGV-0036558_13 | eggNOG-mapper | 1308863.U5J9D4_9CAUD | NA | NA |
| UHGV-0036558_13 | Structural annotation | PF09979, TIGR01543, COG3566 | NA | NA |
| UHGV-0036558_14 | PHROG | phrog_2739 | portal protein | head and packaging |
| UHGV-0036558_14 | UniRef90 | UniRef90_A0A345BPV2 | Putative portal protein | NA |
| UHGV-0036558_14 | eggNOG-mapper | 1308863.U5J9V5_9CAUD | NA | NA |
| UHGV-0036558_14 | Structural annotation | PF05133, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0036558_15 | PHROG | phrog_9084 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_15 | UniRef90 | UniRef90_UPI001CDB5F86 | endonuclease domain-containing protein | NA |
| UHGV-0036558_15 | eggNOG-mapper | 397291.C804_06294 | transposase activity | NA |
| UHGV-0036558_15 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-0036558_15 | Structural annotation | PF18741, MF_04160, NF007294, COG2852 | NA | NA |
| UHGV-0036558_16 | PHROG | phrog_15503 | NA | unknown function |
| UHGV-0036558_16 | UniRef90 | UniRef90_A0A0H3V0N0 | Putative terminase large subunit | NA |
| UHGV-0036558_16 | eggNOG-mapper | 881953.E0YJ34_9CAUD | NA | NA |
| UHGV-0036558_16 | Structural annotation | PF20441, PF04466, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0036558_17 | PHROG | phrog_3314 | NA | unknown function |
| UHGV-0036558_17 | eggNOG-mapper | 1308863.U5J9N3_9CAUD | NA | NA |
| UHGV-0036558_18 | PHROG | phrog_5767 | sigma factor | transcription regulation |
| UHGV-0036558_18 | UniRef90 | UniRef90_A0A345BPU6 | HTH DNA binding domain protein | NA |
| UHGV-0036558_18 | eggNOG-mapper | 1123239.KB898628_gene3218 | NA | NA |
| UHGV-0036558_22 | KOfam | K10761 | THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79] | NA |
| UHGV-0036558_22 | PHROG | phrog_4717 | tRNA-His guanylyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_22 | UniRef90 | UniRef90_A0A414SKK8 | Thg1 domain-containing protein | NA |
| UHGV-0036558_22 | eggNOG-mapper | 742735.HMPREF9467_00875 | tRNAHis guanylyltransferase | NA |
| UHGV-0036558_22 | Pfam | PF04446 | tRNAHis guanylyltransferase | Thg1 |
| UHGV-0036558_22 | COG | COG4021 | tRNA(His) 5'-end guanylyltransferase | NA |
| UHGV-0036558_22 | Structural annotation | PF04446, PF14413, COG4021 | NA | NA |
| UHGV-0036558_41 | PHROG | phrog_20187 | NA | unknown function |
| UHGV-0036558_41 | Structural annotation | PF16473, MF_00045, TIGR01406, COG5018 | NA | NA |
| UHGV-0036558_43 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |
| UHGV-0036558_46 | Structural annotation | PF11019, MF_01022, NF003937, COG4502 | NA | NA |
| UHGV-0036558_49 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |
| UHGV-0036558_56 | Structural annotation | PF18903 | NA | NA |
| UHGV-0036558_70 | Structural annotation | PF01132, TIGR00037, COG0298 | NA | NA |
| UHGV-0036558_75 | Structural annotation | PF01636, NF007684, COG0478 | NA | NA |
| UHGV-0036558_76 | KOfam | K03095 | sprL; SprT-like protein | NA |
| UHGV-0036558_76 | PHROG | phrog_3768 | NA | unknown function |
| UHGV-0036558_76 | eggNOG-mapper | 1122146.AUHP01000017_gene1203 | SprT-like family | NA |
| UHGV-0036558_76 | Pfam | PF10263 | SprT-like family | SprT-like |
| UHGV-0036558_76 | Structural annotation | PF17283, PF01435, MF_00745, NF003339, COG2331 | NA | NA |
| UHGV-0036558_79 | PHROG | phrog_2319 | NA | unknown function |
| UHGV-0036558_79 | UniRef90 | UniRef90_UPI0006A7B5FD | zinc finger-like domain-containing protein | NA |
| UHGV-0036558_79 | eggNOG-mapper | 713586.KB900537_gene3115 | NA | NA |
| UHGV-0036558_79 | Structural annotation | PF17191, MF_01959, NF005050, COG4085 | NA | NA |
| UHGV-0036558_80 | PHROG | phrog_388 | nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_80 | UniRef90 | UniRef90_A0A843FSU3 | Nucleotidyltransferase domain-containing protein | NA |
| UHGV-0036558_83 | Structural annotation | PF19110, MF_01909, NF040939, COG1695 | NA | NA |
| UHGV-0036558_84 | UniRef90 | UniRef90_A0A345BPS5 | Putative protease | NA |
| UHGV-0036558_84 | Structural annotation | PF02581, MF_02232, TIGR01182, COG0135 | NA | NA |
| UHGV-0036558_85 | KOfam | K01258 | pepT; tripeptide aminopeptidase [EC:3.4.11.4] | NA |
| UHGV-0036558_85 | PHROG | phrog_34186 | NA | unknown function |
| UHGV-0036558_85 | UniRef90 | UniRef90_A0A843FCH3 | M28 family peptidase | NA |
| UHGV-0036558_85 | eggNOG-mapper | 935948.KE386495_gene2240 | Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls | NA |
| UHGV-0036558_85 | Pfam | PF04389 | Peptidase family M28 | Peptidase_M28 |
| UHGV-0036558_85 | COG | COG0624 | Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase | NA |
| UHGV-0036558_85 | Structural annotation | PF05343, MF_01120, TIGR01883, COG1363 | NA | NA |
| UHGV-0036558_90 | PHROG | phrog_5018 | NA | unknown function |
| UHGV-0036558_90 | UniRef90 | UniRef90_A0A288TXW0 | PDDEXK_5 domain-containing protein | NA |
| UHGV-0036558_90 | eggNOG-mapper | 1227488.C477_02599 | PD-(D/E)XK endonuclease | NA |
| UHGV-0036558_90 | Pfam | PF11645 | PD-(D/E)XK endonuclease | PDDEXK_5 |
| UHGV-0036558_90 | Structural annotation | PF11645, MF_01490, NF011271, COG4815 | NA | NA |
| UHGV-0036558_91 | PHROG | phrog_5018 | NA | unknown function |
| UHGV-0036558_91 | UniRef90 | UniRef90_UPI001899882C | group I intron-associated PD-(D/E)XK endonuclease | NA |
| UHGV-0036558_91 | Pfam | PF11645 | PD-(D/E)XK endonuclease | PDDEXK_5 |
| UHGV-0036558_91 | Pfam | PF07453 | NUMOD1 domain | NUMOD1 |
| UHGV-0036558_92 | Structural annotation | PF18414 | NA | NA |
| UHGV-0036558_95 | Pfam | PF13306 | BspA type Leucine rich repeat region (6 copies) | LRR_5 |
| UHGV-0036558_96 | KOfam | K22708 | tarS; poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase [EC:2.4.1.355] | NA |
| UHGV-0036558_96 | UniRef90 | UniRef90_A0A2N8HDK2 | Glyco_trans_2-like domain-containing protein | NA |
| UHGV-0036558_96 | eggNOG-mapper | 1123058.KB894224_gene873 | glycosyl transferase family 2 | NA |
| UHGV-0036558_96 | Pfam | PF00535 | Glycosyl transferase family 2 | Glycos_transf_2 |
| UHGV-0036558_96 | COG | COG0463 | Glycosyltransferase involved in cell wall bisynthesis | NA |
| UHGV-0036558_96 | Structural annotation | PF13641, MF_01164, NF007482, COG1216 | NA | NA |
| UHGV-0036558_97 | Structural annotation | PF20010 | NA | NA |
| UHGV-0036558_98 | eggNOG-mapper | 742735.HMPREF9467_00719 | NA | NA |
| UHGV-0036558_99 | PHROG | phrog_15594 | NA | unknown function |
| UHGV-0036558_99 | Structural annotation | PF16640, TIGR04488 | NA | NA |
| UHGV-0036558_102 | eggNOG-mapper | 742733.HMPREF9469_01803 | cellulose 1,4-beta-cellobiosidase activity | NA |
| UHGV-0036558_102 | COG | COG5301 | Phage-related tail fiber protein | NA |
| UHGV-0036558_103 | PHROG | phrog_13712 | holin | lysis |
| UHGV-0036558_103 | Structural annotation | PF09682, TIGR01673 | NA | NA |
| UHGV-0036558_104 | KOfam | K09935 | ybiA; N-glycosidase YbiA [EC:3.2.2.-] | NA |
| UHGV-0036558_104 | PHROG | phrog_1017 | NA | unknown function |
| UHGV-0036558_104 | UniRef90 | UniRef90_A0A7C5AMN8 | NADAR family protein | NA |
| UHGV-0036558_104 | eggNOG-mapper | 411461.DORFOR_00407 | NA | NA |
| UHGV-0036558_104 | Pfam | PF08719 | NADAR domain | NADAR |
| UHGV-0036558_104 | NCBIFam | TIGR02464.1 | conserved hypothetical protein | NA |
| UHGV-0036558_104 | Structural annotation | PF08719, TIGR02464, COG3236 | NA | NA |
| UHGV-0036558_105 | PHROG | phrog_10822 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_105 | UniRef90 | UniRef90_F7K085 | HNHc domain-containing protein | NA |
| UHGV-0036558_105 | eggNOG-mapper | 553174.HMPREF0659_A7222 | HNH nucleases | NA |
| UHGV-0036558_105 | PADLOC | HEase_00002 | homing endonuclease | RM |
| UHGV-0036558_105 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0036558_107 | PHROG | phrog_850 | RNA-binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_107 | UniRef90 | UniRef90_A0A843FJC6 | NA | NA |
| UHGV-0036558_107 | eggNOG-mapper | 1541960.KQ78_01972 | oxidoreductase activity | NA |
| UHGV-0036558_107 | Pfam | PF11443 | NA | DUF2828 |
| UHGV-0036558_107 | COG | COG2304 | Secreted protein containing bacterial Ig-like domain and vWFA domain | NA |
| UHGV-0036558_107 | Structural annotation | PF11443, MF_01340, COG2304 | NA | NA |
| UHGV-0036558_108 | KOfam | K07313 | pphA; serine/threonine protein phosphatase 1 [EC:3.1.3.16] | NA |
| UHGV-0036558_108 | PHROG | phrog_246 | NinI-like serine-threonine phosphatase | other |
| UHGV-0036558_108 | UniRef90 | UniRef90_A0A2K1NVL5 | Metallophosphoesterase | NA |
| UHGV-0036558_108 | eggNOG-mapper | 1280682.AUKA01000008_gene3141 | Calcineurin-like phosphoesterase | NA |
| UHGV-0036558_108 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0036558_108 | COG | COG0639 | Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family | NA |
| UHGV-0036558_108 | Structural annotation | PF12850, MF_01443, NF007425, COG0622 | NA | NA |
| UHGV-0036558_110 | KOfam | K17266 | MVP; major vault protein | NA |
| UHGV-0036558_110 | UniRef90 | UniRef90_A0A345BPD3 | Putative major vault protein | NA |
| UHGV-0036558_110 | eggNOG-mapper | 880071.Fleli_1136 | Shoulder domain | NA |
| UHGV-0036558_110 | Pfam | PF17795 | Major Vault Protein Repeat domain | Vault_3 |
| UHGV-0036558_110 | Pfam | PF11978 | Shoulder domain | MVP_shoulder |
| UHGV-0036558_110 | COG | COG0330 | Regulator of protease activity HflC, stomatin/prohibitin superfamily | NA |
| UHGV-0036558_110 | Structural annotation | PF11978, PF17795, PF17796, MF_01562, TIGR01933, COG0330 | NA | NA |
| UHGV-0036558_112 | UniRef90 | UniRef90_UPI001D104826 | pyrimidine dimer DNA glycosylase/endonuclease V | NA |
| UHGV-0036558_112 | eggNOG-mapper | 272563.CD630_17570 | Pyrimidine dimer DNA glycosylase | NA |
| UHGV-0036558_112 | Pfam | PF03013 | Pyrimidine dimer DNA glycosylase | Pyr_excise |
| UHGV-0036558_112 | Structural annotation | PF03013, TIGR02328 | NA | NA |
| UHGV-0036558_113 | KOfam | K04794 | PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] | NA |
| UHGV-0036558_113 | PHROG | phrog_1866 | NA | unknown function |
| UHGV-0036558_113 | UniRef90 | UniRef90_A0A1I5Y3K7 | Aminoacyl-tRNA hydrolase | NA |
| UHGV-0036558_113 | eggNOG-mapper | 718252.FP2_03850 | Peptidyl-tRNA hydrolase | NA |
| UHGV-0036558_113 | Pfam | PF01981 | Peptidyl-tRNA hydrolase PTH2 | PTH2 |
| UHGV-0036558_113 | COG | COG1990 | Peptidyl-tRNA hydrolase | NA |
| UHGV-0036558_113 | Structural annotation | PF01981, MF_00628, TIGR00283, COG1990 | NA | NA |
| UHGV-0036558_114 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_114 | eggNOG-mapper | 1006000.GKAS_04644 | HNH endonuclease | NA |
| UHGV-0036558_114 | PADLOC | HEase_00016 | homing endonuclease | RM |
| UHGV-0036558_114 | Pfam | PF13392 | HNH endonuclease | HNH_3 |
| UHGV-0036558_114 | Structural annotation | PF13392 | NA | NA |
| UHGV-0036558_116 | KOfam | K18962 | rnlB; T4 RNA ligase 2 [EC:6.5.1.3] | NA |
| UHGV-0036558_116 | PHROG | phrog_968 | RNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_116 | UniRef90 | UniRef90_A0A843GTM3 | RNA_ligase domain-containing protein | NA |
| UHGV-0036558_116 | eggNOG-mapper | 485918.Cpin_2419 | RNA ligase | NA |
| UHGV-0036558_116 | Pfam | PF21189 | PHA02142 OB-fold domain | PHA02142 |
| UHGV-0036558_116 | Pfam | PF09414 | RNA ligase | RNA_ligase |
| UHGV-0036558_116 | COG | COG0073 | tRNA-binding EMAP/Myf domain | NA |
| UHGV-0036558_116 | Structural annotation | PF21189, PF09511, MF_04150, TIGR02306, COG1423, COG0073 | NA | NA |
| UHGV-0036558_118 | PHROG | phrog_1257 | ribosome associated inhibitor A; zinc finger domain | moron, auxiliary metabolic gene and host takeover |
| UHGV-0036558_118 | eggNOG-mapper | 1283338.Q4Z8Y6_BPTWO | NA | NA |
| UHGV-0036558_119 | KOfam | K08073 | PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] | NA |
| UHGV-0036558_119 | PHROG | phrog_6931 | NA | unknown function |
| UHGV-0036558_119 | UniRef90 | UniRef90_A0A345BPY6 | AAA domain protein | NA |
| UHGV-0036558_119 | eggNOG-mapper | 525904.Tter_0838 | AAA domain | NA |
| UHGV-0036558_119 | Pfam | PF13671 | AAA domain | AAA_33 |
| UHGV-0036558_119 | COG | COG0639 | Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family | NA |
| UHGV-0036558_119 | Structural annotation | PF13671, MF_00065, TIGR03574, COG4088 | NA | NA |
| UHGV-0036558_120 | KOfam | K07095 | NA | NA |
| UHGV-0036558_120 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-0036558_120 | UniRef90 | UniRef90_UPI001655871B | metallophosphoesterase family protein | NA |
| UHGV-0036558_120 | eggNOG-mapper | 1392491.JIAE01000001_gene1129 | Calcineurin-like phosphoesterase | NA |
| UHGV-0036558_120 | Pfam | PF12850 | Calcineurin-like phosphoesterase superfamily domain | Metallophos_2 |
| UHGV-0036558_120 | COG | COG4186 | NA | NA |
| UHGV-0036558_120 | Structural annotation | NF006988, COG4186 | NA | NA |
| UHGV-0036558_122 | KOfam | K07175 | phoH2; PhoH-like ATPase | NA |
| UHGV-0036558_122 | PHROG | phrog_2765 | PhoH-like phosphate starvation-inducible | other |
| UHGV-0036558_122 | UniRef90 | UniRef90_A0A843GX46 | PhoH family protein | NA |
| UHGV-0036558_122 | eggNOG-mapper | 1123252.ATZF01000010_gene420 | PIN domain | NA |
| UHGV-0036558_122 | Pfam | PF13638 | PIN domain | PIN_4 |
| UHGV-0036558_122 | Pfam | PF02562 | PhoH-like protein | PhoH |
| UHGV-0036558_122 | COG | COG1875 | Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains | NA |
| UHGV-0036558_122 | Structural annotation | PF02562, PF13638, PF09142, MF_00265, NF007827, NF009148, COG1875 | NA | NA |
| UHGV-0036558_124 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0036558_124 | PHROG | phrog_1794 | amidase | lysis |
| UHGV-0036558_124 | UniRef90 | UniRef90_A0A349YQH7 | SH3b domain-containing protein | NA |
| UHGV-0036558_124 | eggNOG-mapper | 1226322.HMPREF1545_04024 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0036558_124 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0036558_124 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0036558_124 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-0036558_124 | COG | COG3023 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD | NA |
| UHGV-0036558_124 | Structural annotation | PF01510, PF18350, MF_04111, MF_01354, NF008758, COG3023, COG2139 | NA | NA |
| UHGV-0036558_126 | PHROG | phrog_20637 | NA | unknown function |
| UHGV-0036558_126 | UniRef90 | UniRef90_A0A847PL15 | Catalase | NA |
| UHGV-0036558_126 | eggNOG-mapper | 1123250.KB908393_gene223 | NA | NA |
| UHGV-0036558_126 | Pfam | PF18907 | NA | DUF5662 |
| UHGV-0036558_126 | Structural annotation | PF18907 | NA | NA |
| UHGV-0036558_128 | PHROG | phrog_7168 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_128 | UniRef90 | UniRef90_A0A6C0IRK5 | GIY-YIG domain-containing protein | NA |
| UHGV-0036558_128 | eggNOG-mapper | 1004149.AFOE01000033_gene665 | NA | NA |
| UHGV-0036558_128 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0036558_128 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0036558_128 | Structural annotation | PF19835, PF07453, PF20987, TIGR01453 | NA | NA |
| UHGV-0036558_129 | KOfam | K02470 | gyrB; DNA gyrase subunit B [EC:5.6.2.2] | NA |
| UHGV-0036558_129 | PHROG | phrog_543 | DNA topoisomerase II large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_129 | UniRef90 | UniRef90_A0A3B9Z7X0 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0036558_129 | eggNOG-mapper | 717605.Theco_3754 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0036558_129 | Pfam | PF00204 | DNA gyrase B | DNA_gyraseB |
| UHGV-0036558_129 | Pfam | PF01751 | Toprim domain | Toprim |
| UHGV-0036558_129 | Pfam | PF00986 | DNA gyrase B subunit, carboxyl terminus | DNA_gyraseB_C |
| UHGV-0036558_129 | COG | COG0187 | DNA gyrase/topoisomerase IV, subunit B | NA |
| UHGV-0036558_129 | Structural annotation | PF00204, MF_01898, NF004189, COG0187 | NA | NA |
| UHGV-0036558_130 | KOfam | K02469 | gyrA; DNA gyrase subunit A [EC:5.6.2.2] | NA |
| UHGV-0036558_130 | PHROG | phrog_551 | DNA topoisomerase II | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_130 | UniRef90 | UniRef90_A0A832SNJ2 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0036558_130 | eggNOG-mapper | 411489.CLOL250_00955 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0036558_130 | Pfam | PF00521 | DNA gyrase/topoisomerase IV, subunit A | DNA_topoisoIV |
| UHGV-0036558_130 | Pfam | PF03989 | DNA gyrase C-terminal domain, beta-propeller | DNA_gyraseA_C |
| UHGV-0036558_130 | NCBIFam | NF004044.1 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0036558_130 | COG | COG0188 | DNA gyrase/topoisomerase IV, subunit A | NA |
| UHGV-0036558_130 | Structural annotation | PF00521, PF03989, MF_01897, NF004043, COG0188 | NA | NA |
| UHGV-0036558_131 | eggNOG-mapper | 877415.JNJQ01000003_gene1660 | Sh3 type 3 domain protein | NA |
| UHGV-0036558_131 | COG | COG3103 | NA | NA |
| UHGV-0036558_132 | KOfam | K10747 | LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] | NA |
| UHGV-0036558_132 | PHROG | phrog_114 | ATP-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_132 | UniRef90 | UniRef90_A0A345BPZ1 | DNA ligase | NA |
| UHGV-0036558_132 | eggNOG-mapper | 1121121.KB894295_gene4492 | dna ligase | NA |
| UHGV-0036558_132 | Pfam | PF01068 | ATP dependent DNA ligase domain | DNA_ligase_A_M |
| UHGV-0036558_132 | COG | COG1793 | ATP-dependent DNA ligase | NA |
| UHGV-0036558_132 | Structural annotation | PF01068, MF_00407, TIGR02779, COG1793 | NA | NA |
| UHGV-0036558_134 | Structural annotation | PF04182, MF_01909, NF040939, COG1675 | NA | NA |
| UHGV-0036558_135 | PHROG | phrog_7168 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_135 | UniRef90 | UniRef90_A0A843GN52 | GIY-YIG nuclease family protein | NA |
| UHGV-0036558_135 | eggNOG-mapper | 1427984.X271_00109 | NA | NA |
| UHGV-0036558_135 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0036558_135 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0036558_135 | Structural annotation | PF19835, TIGR01453 | NA | NA |
| UHGV-0036558_136 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-0036558_136 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-0036558_136 | UniRef90 | UniRef90_A0A1T4P123 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-0036558_136 | eggNOG-mapper | 537007.BLAHAN_05297 | Clp protease | NA |
| UHGV-0036558_136 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-0036558_136 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-0036558_137 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0036558_137 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_137 | UniRef90 | UniRef90_A0A7X2NTD7 | FAD-dependent thymidylate synthase | NA |
| UHGV-0036558_137 | eggNOG-mapper | 1121296.JONJ01000007_gene2080 | thymidylate synthase (FAD) activity | NA |
| UHGV-0036558_137 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0036558_137 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0036558_137 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0036558_138 | UniRef90 | UniRef90_A0A843FPF0 | Winged helix-turn-helix domain-containing protein | NA |
| UHGV-0036558_138 | Structural annotation | PF03444, MF_00732, TIGR02337, COG1321 | NA | NA |
| UHGV-0036558_139 | eggNOG-mapper | 10736.A0A1P8CX09_BPPHT | NA | NA |
| UHGV-0036558_139 | Structural annotation | PF00436, PF19649, MF_00984, NF004476, COG2965 | NA | NA |
| UHGV-0036558_140 | PHROG | phrog_124 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_140 | UniRef90 | UniRef90_A0A832SVD6 | ATP-binding protein | NA |
| UHGV-0036558_140 | eggNOG-mapper | 1541960.KQ78_01919 | Belongs to the helicase family. UvrD subfamily | NA |
| UHGV-0036558_140 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-0036558_140 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-0036558_140 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-0036558_141 | PHROG | phrog_4680 | NA | unknown function |
| UHGV-0036558_141 | UniRef90 | UniRef90_A0A3S4N9I4 | NA | NA |
| UHGV-0036558_141 | eggNOG-mapper | 1280.SAXN108_2226 | NA | NA |
| UHGV-0036558_141 | Structural annotation | PF02069 | NA | NA |
| UHGV-0036558_142 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0036558_142 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_142 | UniRef90 | UniRef90_A0A843FVR3 | DNA helicase | NA |
| UHGV-0036558_142 | eggNOG-mapper | 537007.BLAHAN_05495 | DnaB-like helicase C terminal domain | NA |
| UHGV-0036558_142 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-0036558_142 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0036558_142 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0036558_142 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0036558_144 | PHROG | phrog_47 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_144 | UniRef90 | UniRef90_A0A345BPU0 | DNA primase | NA |
| UHGV-0036558_144 | eggNOG-mapper | 1434319.W5RVC4_9CAUD | DNA primase activity | NA |
| UHGV-0036558_144 | Structural annotation | PF01807, PF19898, MF_00974, NF006382, COG0358 | NA | NA |
| UHGV-0036558_145 | Structural annotation | PF11331, TIGR02098 | NA | NA |
| UHGV-0036558_146 | KOfam | K07462 | recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] | NA |
| UHGV-0036558_146 | PHROG | phrog_2484 | RecJ-like ssDNA exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_146 | UniRef90 | UniRef90_A0A843GQK3 | DHH family phosphoesterase | NA |
| UHGV-0036558_146 | eggNOG-mapper | 224308.BSU20350 | Single-stranded-DNA-specific exonuclease RecJ | NA |
| UHGV-0036558_146 | Pfam | PF01368 | DHH family | DHH |
| UHGV-0036558_146 | Pfam | PF17768 | RecJ OB domain | RecJ_OB |
| UHGV-0036558_146 | COG | COG0608 | ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation | NA |
| UHGV-0036558_146 | Structural annotation | PF17768, PF02272, MF_00207, TIGR00644, COG0608 | NA | NA |
| UHGV-0036558_147 | PHROG | phrog_289 | GTP-binding domain | other |
| UHGV-0036558_147 | UniRef90 | UniRef90_A0A416U1L4 | NA | NA |
| UHGV-0036558_147 | eggNOG-mapper | 1308863.U5J9F7_9CAUD | NA | NA |
| UHGV-0036558_147 | Structural annotation | PF06908, MF_01575, NF010181, COG4474 | NA | NA |
| UHGV-0036558_150 | KOfam | K03581 | recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] | NA |
| UHGV-0036558_150 | PHROG | phrog_325 | Dda-like helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_150 | UniRef90 | UniRef90_A0A843GQ82 | AAA family ATPase | NA |
| UHGV-0036558_150 | eggNOG-mapper | 1121085.AUCI01000012_gene2815 | A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD | NA |
| UHGV-0036558_150 | PADLOC | cluster10 | RecD_0_IVD | CRISPR-CAS |
| UHGV-0036558_150 | Pfam | PF13604 | AAA domain | AAA_30 |
| UHGV-0036558_150 | Pfam | PF13538 | UvrD-like helicase C-terminal domain | UvrD_C_2 |
| UHGV-0036558_150 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0036558_150 | Structural annotation | PF13604, MF_01488, TIGR01448, COG0507 | NA | NA |
| UHGV-0036558_151 | KOfam | K07451 | mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] | NA |
| UHGV-0036558_151 | PHROG | phrog_589 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_151 | UniRef90 | UniRef90_A0A420GM79 | HNHc domain-containing protein | NA |
| UHGV-0036558_151 | eggNOG-mapper | 1408323.JQKK01000043_gene823 | Resolvase, N terminal domain | NA |
| UHGV-0036558_151 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0036558_151 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-0036558_153 | KOfam | K02337 | dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] | NA |
| UHGV-0036558_153 | PHROG | phrog_405 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_153 | UniRef90 | UniRef90_A0A843GL03 | DNA-directed DNA polymerase | NA |
| UHGV-0036558_153 | eggNOG-mapper | 224308.BSU20340 | DNA polymerase | NA |
| UHGV-0036558_153 | Pfam | PF02811 | PHP domain | PHP |
| UHGV-0036558_153 | Pfam | PF07733 | Bacterial DNA polymerase III alpha NTPase domain | DNA_pol3_alpha |
| UHGV-0036558_153 | Pfam | PF17657 | Bacterial DNA polymerase III alpha subunit finger domain | DNA_pol3_finger |
| UHGV-0036558_153 | Pfam | PF14579 | Helix-hairpin-helix motif | HHH_6 |
| UHGV-0036558_153 | COG | COG0587 | DNA polymerase III, alpha subunit | NA |
| UHGV-0036558_153 | Structural annotation | PF07733, PF02811, PF17657, PF14579, MF_01902, NF005617, COG0587 | NA | NA |
| UHGV-0036558_154 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-0036558_154 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-0036558_154 | UniRef90 | UniRef90_A0A401UTJ7 | Guanylate kinase | NA |
| UHGV-0036558_154 | eggNOG-mapper | 941824.TCEL_01796 | Essential for recycling GMP and indirectly, cGMP | NA |
| UHGV-0036558_154 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-0036558_154 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-0036558_154 | Structural annotation | PF00625, MF_00328, NF011324, COG0194 | NA | NA |
| UHGV-0036558_155 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-0036558_155 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-0036558_155 | UniRef90 | UniRef90_A0A1H9D9B0 | Ribonucleoside-triphosphate reductase class III catalytic subunit | NA |
| UHGV-0036558_155 | eggNOG-mapper | 877415.JNJQ01000044_gene1829 | NA | NA |
| UHGV-0036558_155 | Pfam | PF03477 | ATP cone domain | ATP-cone |
| UHGV-0036558_155 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-0036558_155 | NCBIFam | NF006732.0 | anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0036558_155 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0036558_155 | Structural annotation | PF13597, PF03477, MF_00440, NF006732, COG1328 | NA | NA |
| UHGV-0036558_159 | Structural annotation | PF10750, MF_01122, TIGR00285, COG1581 | NA | NA |
| UHGV-0036558_160 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-0036558_160 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_160 | UniRef90 | UniRef90_A0A832SET9 | dUTP diphosphatase | NA |
| UHGV-0036558_160 | eggNOG-mapper | 1408436.JHXY01000007_gene317 | This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | NA |
| UHGV-0036558_160 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-0036558_160 | NCBIFam | TIGR00576.1 | dUTP diphosphatase | NA |
| UHGV-0036558_160 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-0036558_160 | Structural annotation | PF00692, MF_00116, NF001862, COG0756 | NA | NA |
| UHGV-0036558_161 | KOfam | K01159 | ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] | NA |
| UHGV-0036558_161 | PHROG | phrog_827 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0036558_161 | UniRef90 | UniRef90_A0A345BPU5 | Crossover junction endodeoxyribonuclease RuvC | NA |
| UHGV-0036558_161 | eggNOG-mapper | 180332.JTGN01000008_gene4067 | NA | NA |
| UHGV-0036558_161 | Pfam | PF02075 | Crossover junction endodeoxyribonuclease RuvC | RuvC |
| UHGV-0036558_161 | Structural annotation | PF07066, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-0036558_162 | PHROG | phrog_1233 | NA | unknown function |
| UHGV-0036558_162 | UniRef90 | UniRef90_A0A345BPX6 | Metal-dependent hydrolase | NA |
| UHGV-0036558_162 | eggNOG-mapper | 658655.HMPREF0988_00914 | NA | NA |
| UHGV-0036558_162 | Structural annotation | PF13058 | NA | NA |
| UHGV-0036558_163 | eggNOG-mapper | 658655.HMPREF0988_00915 | NA | NA |
| UHGV-0036558_164 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-0036558_164 | UniRef90 | UniRef90_A0A345BPX4 | Carbohydrate binding domain/collagen triple helix repeat protein | NA |
| UHGV-0036558_164 | eggNOG-mapper | 397290.C810_05214 | NA | NA |
| UHGV-0036558_164 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-0036558_165 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0036558_165 | eggNOG-mapper | 658655.HMPREF0988_00917 | NA | NA |
| UHGV-0036558_166 | eggNOG-mapper | 476272.RUMHYD_01953 | NA | NA |
| UHGV-0036558_172 | PHROG | phrog_25468 | NA | unknown function |
| UHGV-0036558_173 | PHROG | phrog_32343 | NA | unknown function |
| UHGV-0036558_173 | UniRef90 | UniRef90_A0A345BPW9 | Putative flagellin-like protein | NA |
| UHGV-0036558_173 | eggNOG-mapper | 483218.BACPEC_01060 | NA | NA |
| UHGV-0036558_173 | Structural annotation | PF06605, COG4379 | NA | NA |
| UHGV-0036558_174 | PHROG | phrog_30026 | NA | unknown function |
| UHGV-0036558_174 | Structural annotation | PF02010, PF06995, NF040520, COG4718, COG2372 | NA | NA |
| UHGV-0036558_178 | PHROG | phrog_4211 | tail length tape measure protein | tail |