| UHGV-0041241_1 | Pfam | PF08272 | Topoisomerase I zinc-ribbon-like | Topo_Zn_Ribbon |
| UHGV-0041241_5 | PHROG | phrog_24896 | NA | unknown function |
| UHGV-0041241_5 | UniRef90 | UniRef90_UPI00189AD407 | leucine-rich repeat protein | NA |
| UHGV-0041241_5 | eggNOG-mapper | 762968.HMPREF9441_03606 | NA | NA |
| UHGV-0041241_5 | Structural annotation | PF08757, PF13385, PF16397, MF_04116, NF041740, COG4743 | NA | NA |
| UHGV-0041241_7 | eggNOG-mapper | 1227276.HMPREF9148_02473 | serine threonine protein kinase | NA |
| UHGV-0041241_7 | Pfam | PF13306 | BspA type Leucine rich repeat region (6 copies) | LRR_5 |
| UHGV-0041241_7 | COG | COG0515 | Serine/threonine protein kinase | NA |
| UHGV-0041241_10 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0041241_12 | eggNOG-mapper | 471854.Dfer_5528 | NA | NA |
| UHGV-0041241_13 | PHROG | phrog_554 | NA | unknown function |
| UHGV-0041241_19 | KOfam | K03427 | hsdM; type I restriction enzyme M protein [EC:2.1.1.72] | NA |
| UHGV-0041241_19 | PHROG | phrog_5696 | NA | unknown function |
| UHGV-0041241_19 | UniRef90 | UniRef90_A0A6L5XAE6 | N-6 DNA methylase | NA |
| UHGV-0041241_19 | eggNOG-mapper | 1403948.Q618_VCMC00001G0774 | type I restriction-modification system | NA |
| UHGV-0041241_19 | PADLOC | MTase_I_00004 | Type I methyltransferase | RM |
| UHGV-0041241_19 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-0041241_19 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-0041241_19 | Structural annotation | COG0286 | NA | NA |
| UHGV-0041241_20 | Structural annotation | PF14528, NF007435 | NA | NA |
| UHGV-0041241_30 | PHROG | phrog_7964 | NA | unknown function |
| UHGV-0041241_30 | eggNOG-mapper | 679189.HMPREF9019_0902 | lipid A biosynthetic process | NA |
| UHGV-0041241_30 | COG | COG1044 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase | NA |
| UHGV-0041241_33 | Structural annotation | PF06289, COG1582 | NA | NA |
| UHGV-0041241_34 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-0041241_34 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0041241_34 | UniRef90 | UniRef90_A0A2L2WS96 | DNA ligase (NAD(+)) | NA |
| UHGV-0041241_34 | eggNOG-mapper | 393921.HQ45_04010 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-0041241_34 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-0041241_34 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0041241_34 | Structural annotation | PF01653, PF03120, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-0041241_36 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-0041241_36 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-0041241_36 | UniRef90 | UniRef90_A0A095Z6L5 | AAA_31 domain-containing protein | NA |
| UHGV-0041241_36 | eggNOG-mapper | 1236504.HMPREF2132_02105 | CobQ CobB MinD ParA nucleotide binding domain | NA |
| UHGV-0041241_36 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-0041241_36 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-0041241_36 | Structural annotation | PF13614, MF_00533, NF041283, COG1192 | NA | NA |
| UHGV-0041241_37 | Structural annotation | PF07878, COG3905 | NA | NA |
| UHGV-0041241_38 | UniRef90 | UniRef90_D1PE27 | RepB family plasmid replication initiator protein | NA |
| UHGV-0041241_38 | eggNOG-mapper | 1095752.HMPREF9969_0713 | Initiator RepB protein | NA |
| UHGV-0041241_38 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-0041241_38 | Structural annotation | PF20964, PF01051, NF038290, COG5527 | NA | NA |
| UHGV-0041241_41 | Structural annotation | PF17457 | NA | NA |
| UHGV-0041241_42 | Structural annotation | COG3655 | NA | NA |
| UHGV-0041241_45 | UniRef90 | UniRef90_A0A096AGU9 | FHA domain-containing protein | NA |
| UHGV-0041241_45 | eggNOG-mapper | 1236504.HMPREF2132_01700 | DNA primase activity | NA |
| UHGV-0041241_45 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0041241_45 | Structural annotation | PF05272, PF01807, MF_00974, MF_00016, NF005477, COG3378, COG0358 | NA | NA |
| UHGV-0041241_47 | PHROG | phrog_11581 | NA | unknown function |
| UHGV-0041241_47 | eggNOG-mapper | 470145.BACCOP_01179 | NA | NA |
| UHGV-0041241_49 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-0041241_49 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-0041241_49 | UniRef90 | UniRef90_A0A2A5WXW2 | Beta sliding clamp | NA |
| UHGV-0041241_49 | eggNOG-mapper | 1236504.HMPREF2132_01710 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-0041241_49 | Pfam | PF02768 | DNA polymerase III beta subunit, C-terminal domain | DNA_pol3_beta_3 |
| UHGV-0041241_49 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-0041241_49 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-0041241_59 | PHROG | phrog_7964 | NA | unknown function |
| UHGV-0041241_59 | UniRef90 | UniRef90_UPI00148E74AF | polymer-forming cytoskeletal protein | NA |
| UHGV-0041241_59 | eggNOG-mapper | 1403946.Q615_SPAC00127G0158 | Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | NA |
| UHGV-0041241_59 | Pfam | PF18836 | YdcK Beta solenoid repeat | B_solenoid_ydck |
| UHGV-0041241_59 | COG | COG1044 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase | NA |
| UHGV-0041241_59 | Structural annotation | NF040481 | NA | NA |
| UHGV-0041241_60 | eggNOG-mapper | 1002367.HMPREF0673_02207 | NA | NA |
| UHGV-0041241_60 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-0041241_61 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-0041241_61 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-0041241_61 | UniRef90 | UniRef90_A0A255TPS1 | Methyltransferase | NA |
| UHGV-0041241_61 | eggNOG-mapper | 667015.Bacsa_0489 | Belongs to the N(4) N(6)-methyltransferase family | NA |
| UHGV-0041241_61 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-0041241_61 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-0041241_61 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-0041241_61 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-0041241_62 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-0041241_62 | UniRef90 | UniRef90_A0A096B9T1 | Conjugal transfer protein | NA |
| UHGV-0041241_62 | eggNOG-mapper | 1236504.HMPREF2132_01885 | DNA restriction-modification system | NA |
| UHGV-0041241_62 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-0041241_62 | Structural annotation | PF19587, MF_01872, NF011489, COG0286 | NA | NA |
| UHGV-0041241_63 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-0041241_63 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0041241_63 | UniRef90 | UniRef90_A0A2L2WN54 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-0041241_63 | eggNOG-mapper | 762982.HMPREF9442_01221 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-0041241_63 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-0041241_63 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0041241_63 | Structural annotation | PF01507, MF_00064, NF006327, COG0175 | NA | NA |
| UHGV-0041241_64 | PHROG | phrog_9298 | radical SAM domain protein | other |
| UHGV-0041241_64 | UniRef90 | UniRef90_A0A2L2WN84 | Radical SAM protein | NA |
| UHGV-0041241_64 | eggNOG-mapper | 762968.HMPREF9441_00539 | radical SAM domain protein | NA |
| UHGV-0041241_64 | COG | COG1032 | Radical SAM superfamily enzyme YgiQ, UPF0313 family | NA |
| UHGV-0041241_64 | Structural annotation | MF_01865, TIGR00089, COG0621 | NA | NA |
| UHGV-0041241_66 | UniRef90 | UniRef90_UPI001C2BD57F | phage holin family protein | NA |
| UHGV-0041241_66 | eggNOG-mapper | 457424.BFAG_02443 | NA | NA |
| UHGV-0041241_66 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0041241_66 | Structural annotation | TIGR01593 | NA | NA |
| UHGV-0041241_67 | Structural annotation | PF20765 | NA | NA |
| UHGV-0041241_69 | PHROG | phrog_25337 | tail length tape measure protein | tail |
| UHGV-0041241_69 | UniRef90 | UniRef90_A0A2L2WS53 | PhageMin_Tail domain-containing protein | NA |
| UHGV-0041241_69 | eggNOG-mapper | 1236504.HMPREF2132_01670 | tail tape measure protein, TP901 family | NA |
| UHGV-0041241_69 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0041241_69 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0041241_69 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-0041241_69 | Structural annotation | PF10145, TIGR01760 | NA | NA |
| UHGV-0041241_71 | UniRef90 | UniRef90_A0A2L2WND9 | Primase C terminal 2 | NA |
| UHGV-0041241_71 | eggNOG-mapper | 1236504.HMPREF2132_01765 | Primase C terminal 2 (PriCT-2) | NA |
| UHGV-0041241_71 | PADLOC | drt-cluster64 | DRT | DRT |
| UHGV-0041241_71 | Pfam | PF08800 | BT4734-like, N-terminal domain | BT4734-like_N |
| UHGV-0041241_71 | Pfam | PF08707 | Primase C terminal 2 (PriCT-2) | PriCT_2 |
| UHGV-0041241_71 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-0041241_71 | Structural annotation | PF08800, PF08707, NF040562 | NA | NA |
| UHGV-0041241_72 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-0041241_72 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-0041241_72 | UniRef90 | UniRef90_A0A354WXC5 | Guanylate kinase | NA |
| UHGV-0041241_72 | eggNOG-mapper | 1262449.CP6013_1905 | Guanylate kinase | NA |
| UHGV-0041241_72 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-0041241_72 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-0041241_72 | Structural annotation | PF00625, MF_00328, NF011324, COG0194 | NA | NA |
| UHGV-0041241_73 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0041241_73 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0041241_73 | UniRef90 | UniRef90_A0A7M1RXG2 | Flavin-dependent thymidylate synthase | NA |
| UHGV-0041241_73 | eggNOG-mapper | 1236504.HMPREF2132_01775 | thymidylate synthase (FAD) activity | NA |
| UHGV-0041241_73 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0041241_73 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0041241_73 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0041241_74 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-0041241_74 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-0041241_74 | UniRef90 | UniRef90_A0A413BUZ6 | NA | NA |
| UHGV-0041241_74 | eggNOG-mapper | 264203.ZMO1191 | This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | NA |
| UHGV-0041241_74 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-0041241_74 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-0041241_74 | Structural annotation | PF00692, MF_00116, NF001862, COG0756 | NA | NA |
| UHGV-0041241_77 | Structural annotation | PF11550, COG5437 | NA | NA |
| UHGV-0041241_78 | KOfam | K21511 | GPC; capsid assembly protease [EC:3.4.21.-] | NA |
| UHGV-0041241_78 | PHROG | phrog_53 | head maturation protease | head and packaging |
| UHGV-0041241_78 | UniRef90 | UniRef90_A0A2L2WN07 | Signal peptide peptidase SppA, 36K type | NA |
| UHGV-0041241_78 | eggNOG-mapper | 1236504.HMPREF2132_01855 | serine-type peptidase activity | NA |
| UHGV-0041241_78 | Pfam | PF01343 | Peptidase family S49 | Peptidase_S49 |
| UHGV-0041241_78 | COG | COG0616 | Periplasmic serine protease, ClpP class | NA |
| UHGV-0041241_78 | Structural annotation | PF01343, MF_00444, TIGR00706, COG0616 | NA | NA |
| UHGV-0041241_79 | eggNOG-mapper | 1002367.HMPREF0673_02214 | NA | NA |
| UHGV-0041241_79 | Structural annotation | PF05065, PF18998, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0041241_80 | Structural annotation | TIGR01603, COG5437 | NA | NA |
| UHGV-0041241_81 | KOfam | K11921 | cynR; LysR family transcriptional regulator, cyn operon transcriptional activator | NA |
| UHGV-0041241_81 | PHROG | phrog_3736 | NA | unknown function |
| UHGV-0041241_81 | UniRef90 | UniRef90_A0A353E8E6 | HTH lysR-type domain-containing protein | NA |
| UHGV-0041241_81 | eggNOG-mapper | 762982.HMPREF9442_01735 | LysR substrate binding domain | NA |
| UHGV-0041241_81 | Pfam | PF00126 | Bacterial regulatory helix-turn-helix protein, lysR family | HTH_1 |
| UHGV-0041241_81 | Pfam | PF03466 | LysR substrate binding domain | LysR_substrate |
| UHGV-0041241_81 | COG | COG0583 | DNA-binding transcriptional regulator, LysR family | NA |
| UHGV-0041241_81 | Structural annotation | PF03466, PF00126, MF_01233, NF040786, COG0583 | NA | NA |
| UHGV-0041241_84 | Structural annotation | PF10628 | NA | NA |
| UHGV-0041241_87 | KOfam | K22918 | ttsA; typhoid toxin secretion A | NA |
| UHGV-0041241_87 | PHROG | phrog_315 | endolysin | lysis |
| UHGV-0041241_87 | UniRef90 | UniRef90_A0A353E8E0 | Peptidoglycan domain protein | NA |
| UHGV-0041241_87 | eggNOG-mapper | 1122981.AUME01000026_gene513 | Glycosyl hydrolase 108 | NA |
| UHGV-0041241_87 | Pfam | PF05838 | Glycosyl hydrolase 108 | Glyco_hydro_108 |
| UHGV-0041241_87 | Pfam | PF09374 | Predicted Peptidoglycan domain | PG_binding_3 |
| UHGV-0041241_87 | COG | COG3926 | Lysozyme family protein | NA |
| UHGV-0041241_87 | Structural annotation | PF05838, PF09374, NF040573, COG3926 | NA | NA |
| UHGV-0041241_89 | PHROG | phrog_874 | NA | unknown function |
| UHGV-0041241_89 | eggNOG-mapper | 1122991.BAIZ01000025_gene1864 | NA | NA |
| UHGV-0041241_89 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-0041241_91 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0041241_93 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0041241_93 | UniRef90 | UniRef90_A0A3C1E386 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0041241_93 | eggNOG-mapper | 857571.EA1_08462 | COG0270 Site-specific DNA methylase | NA |
| UHGV-0041241_93 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0041241_93 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0041241_94 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0041241_94 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0041241_94 | UniRef90 | UniRef90_A0A3C1E2Y5 | Cytosine-specific methyltransferase | NA |
| UHGV-0041241_94 | eggNOG-mapper | 1033733.CAEK01000007_gene1648 | Cytosine-specific methyltransferase | NA |
| UHGV-0041241_94 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-0041241_94 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0041241_94 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0041241_94 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0041241_94 | Structural annotation | PF00145, MF_00786, TIGR00675, COG0270 | NA | NA |
| UHGV-0041241_100 | Structural annotation | PF18195, COG5475 | NA | NA |
| UHGV-0041241_101 | Structural annotation | NF040488 | NA | NA |
| UHGV-0041241_104 | eggNOG-mapper | 1235803.C825_03414 | NA | NA |
| UHGV-0041241_104 | Structural annotation | PF05136, MF_04135, TIGR01540, COG5518 | NA | NA |
| UHGV-0041241_105 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-0041241_105 | PHROG | phrog_12862 | NA | unknown function |
| UHGV-0041241_105 | UniRef90 | UniRef90_UPI001B8799D0 | site-specific DNA-methyltransferase | NA |
| UHGV-0041241_105 | eggNOG-mapper | 1462526.BN990_03861 | DNA methylase | NA |
| UHGV-0041241_105 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-0041241_105 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-0041241_105 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-0041241_105 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-0041241_106 | Pfam | PF20459 | NA | DUF6712 |
| UHGV-0041241_106 | Structural annotation | PF20459 | NA | NA |
| UHGV-0041241_111 | PHROG | phrog_26822 | NA | unknown function |
| UHGV-0041241_111 | eggNOG-mapper | 445970.ALIPUT_01638 | cellulase activity | NA |
| UHGV-0041241_111 | COG | COG4926 | Phage-related protein | NA |