UHGV-0158551

Genome information

Genome length 63,244 bps

CDS count 93

Completeness 98.19% (high-quality)

geNomad score 0.9727

Prediction confidence Confident

Genome information
Genome ID	UHGV-0158551
vOTU ID	vOTU-010669
vOTU representative	Yes
Source dataset	GPD
Original genome ID	uvig_493269
BioSample	SAMN06110205
Country	Netherlands
Virus prediction confidence	Confident

Quality assessment
CheckV method	AAI-based
CheckV completeness	98.19% (high-quality)
CheckV contamination	0.00%
Trimmed provirus	Yes
CheckV viral markers	25
CheckV host markers	1
Recoded stop codon	No

Viral signal
geNomad score	0.9727
Virus hallmark genes (geNomad)	8
Plasmid hallmark genes (geNomad)	0
viralVerify prediction	Virus
viralVerify score	22.36
Jumbo phage	No

Genome content
Genome length	63,244 bps
GC content	55.93%
Genetic code	The standard bacterial, archaeal and plant plastid code (11)
CDS count	93
CDS density	89.43%
Average CDS length	610.87 bps
tRNA count	5
Suppressor tRNA genes	0

Genome content

Select view: Genome viewer Functional annotation

Functional annotation

Gene ID	Reference	Reference ID	Information	Category
UHGV-0158551_1	KOfam	K14059	int; integrase	NA
UHGV-0158551_1	PHROG	phrog_1	integrase	integration and excision
UHGV-0158551_1	UniRef90	UniRef90_A7A5K0	Site-specific recombinase, phage integrase family	NA
UHGV-0158551_1	eggNOG-mapper	1437603.BMON_0921	Phage integrase family	NA
UHGV-0158551_1	Pfam	PF14659	Phage integrase, N-terminal SAM-like domain	Phage_int_SAM_3
UHGV-0158551_1	Pfam	PF00589	Phage integrase family	Phage_integrase
UHGV-0158551_1	COG	COG0582	Integrase/recombinase, includes phage integrase	NA
UHGV-0158551_1	Structural annotation	PF00589, PF13102, MF_01808, TIGR02225, COG4974	NA	NA
UHGV-0158551_3	KOfam	K01447	xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]	NA
UHGV-0158551_3	PHROG	phrog_19265	NA	unknown function
UHGV-0158551_3	UniRef90	UniRef90_B6XUG6	N-acetylmuramoyl-L-alanine amidase	NA
UHGV-0158551_3	eggNOG-mapper	566552.BIFCAT_00851	N-acetylmuramoyl-L-alanine amidase	NA
UHGV-0158551_3	Pfam	PF01510	N-acetylmuramoyl-L-alanine amidase	Amidase_2
UHGV-0158551_3	COG	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	NA
UHGV-0158551_3	Structural annotation	PF01510, MF_04111, NF008758, COG3023	NA	NA
UHGV-0158551_4	PHROG	phrog_263	holin	lysis
UHGV-0158551_4	UniRef90	UniRef90_B6XUG7	Putative holin, SPP1 family	NA
UHGV-0158551_4	eggNOG-mapper	566552.BIFCAT_00852	SPP1 phage holin	NA
UHGV-0158551_4	Pfam	PF04688	SPP1 phage holin	Holin_SPP1
UHGV-0158551_5	PHROG	phrog_1397	NA	unknown function
UHGV-0158551_5	UniRef90	UniRef90_A0A1X2ZMT4	PRTRC system protein E	NA
UHGV-0158551_5	eggNOG-mapper	78345.BMERY_0865	NA	NA
UHGV-0158551_6	eggNOG-mapper	566552.BIFCAT_00857	NA	NA
UHGV-0158551_7	PHROG	phrog_1885	minor tail protein	tail
UHGV-0158551_7	UniRef90	UniRef90_A0A1X2ZMQ5	Autotransporter adhesin	NA
UHGV-0158551_7	eggNOG-mapper	566552.BIFCAT_00858	nuclear chromosome segregation	NA
UHGV-0158551_7	COG	COG1196	Chromosome segregation ATPase Smc	NA
UHGV-0158551_8	PHROG	phrog_1885	minor tail protein	tail
UHGV-0158551_8	UniRef90	UniRef90_A0A087B699	Putative major tail protein	NA
UHGV-0158551_8	eggNOG-mapper	35760.BCHO_0828	NA	NA
UHGV-0158551_8	Structural annotation	PF14594, TIGR01665, COG4379	NA	NA
UHGV-0158551_9	PHROG	phrog_3398	virion structural protein	head and packaging
UHGV-0158551_9	UniRef90	UniRef90_A0A087B698	Putative phage protein gp45	NA
UHGV-0158551_9	eggNOG-mapper	566552.BIFCAT_00860	NA	NA
UHGV-0158551_9	Structural annotation	PF05475, NF033147, COG4935	NA	NA
UHGV-0158551_10	PHROG	phrog_5577	minor tail protein	tail
UHGV-0158551_10	UniRef90	UniRef90_A0A087B697	Putative phage protein gp15	NA
UHGV-0158551_10	eggNOG-mapper	1435051.BMOU_0767	NA	NA
UHGV-0158551_10	Structural annotation	PF20753, PF16774, TIGR01633, COG4722	NA	NA
UHGV-0158551_11	PHROG	phrog_305	tail length tape measure protein	tail
UHGV-0158551_11	UniRef90	UniRef90_A0A1X2Z8L9	Structural protein	NA
UHGV-0158551_11	eggNOG-mapper	35760.BCHO_0831	domain protein	NA
UHGV-0158551_11	COG	COG0840	Methyl-accepting chemotaxis protein (MCP)	NA
UHGV-0158551_13	PHROG	phrog_36579	NA	unknown function
UHGV-0158551_14	PHROG	phrog_117	major tail protein	tail
UHGV-0158551_14	UniRef90	UniRef90_A0A087AF65	Gp22	NA
UHGV-0158551_14	eggNOG-mapper	35760.BCHO_0834	NA	NA
UHGV-0158551_14	Structural annotation	PF04630, TIGR01603, COG5437	NA	NA
UHGV-0158551_15	eggNOG-mapper	35760.BCHO_0835	NA	NA
UHGV-0158551_15	Structural annotation	PF12691	NA	NA
UHGV-0158551_16	PHROG	phrog_32608	NA	unknown function
UHGV-0158551_16	Structural annotation	PF17395	NA	NA
UHGV-0158551_17	PHROG	phrog_25853	NA	unknown function
UHGV-0158551_17	UniRef90	UniRef90_A0A0A7I3R4	Thiamine biosynthesis protein ThiS	NA
UHGV-0158551_17	eggNOG-mapper	35760.BCHO_0837	NA	NA
UHGV-0158551_17	Structural annotation	PF12206, COG5614	NA	NA
UHGV-0158551_18	PHROG	phrog_36776	NA	unknown function
UHGV-0158551_18	eggNOG-mapper	1692.BMAGN_1447	NA	NA
UHGV-0158551_19	PHROG	phrog_29	major head protein	head and packaging
UHGV-0158551_19	UniRef90	UniRef90_UPI0018C2985B	major capsid protein	NA
UHGV-0158551_19	eggNOG-mapper	1692.BMAGN_1446	Phage major capsid protein E	NA
UHGV-0158551_19	Pfam	PF03864	Phage major capsid protein E	Phage_cap_E
UHGV-0158551_19	Structural annotation	PF03864, MF_04133, TIGR04387, COG4653	NA	NA
UHGV-0158551_20	PHROG	phrog_3583	head decoration	head and packaging
UHGV-0158551_20	UniRef90	UniRef90_A0A087B687	Bacteriophage lambda head decoration like-protein	NA
UHGV-0158551_20	eggNOG-mapper	1692.BMAGN_1445	NA	NA
UHGV-0158551_20	Structural annotation	PF02924	NA	NA
UHGV-0158551_21	UniRef90	UniRef90_A0A087B686	Putative phage protein gp5	NA
UHGV-0158551_21	eggNOG-mapper	35760.BCHO_0841	NA	NA
UHGV-0158551_22	PHROG	phrog_36668	NA	unknown function
UHGV-0158551_22	UniRef90	UniRef90_A0A7Y0EP42	NA	NA
UHGV-0158551_22	eggNOG-mapper	1692.BMAGN_1443	NA	NA
UHGV-0158551_22	Structural annotation	PF06152, TIGR01641, COG2369	NA	NA
UHGV-0158551_23	PHROG	phrog_104	portal protein	head and packaging
UHGV-0158551_23	UniRef90	UniRef90_A0A1X3A1Q2	Portal protein	NA
UHGV-0158551_23	eggNOG-mapper	1692.BMAGN_1442	NA	NA
UHGV-0158551_23	Structural annotation	PF05133, MF_04120, TIGR01538, COG5511	NA	NA
UHGV-0158551_24	PHROG	phrog_9	terminase large subunit	head and packaging
UHGV-0158551_24	UniRef90	UniRef90_UPI001F0F6B49	phage terminase family protein	NA
UHGV-0158551_24	eggNOG-mapper	1692.BMAGN_1441	Terminase	NA
UHGV-0158551_24	COG	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	NA
UHGV-0158551_24	Structural annotation	PF20441, PF03354, MF_04145, TIGR01547, COG4626	NA	NA
UHGV-0158551_25	PHROG	phrog_226	minor tail protein	tail
UHGV-0158551_26	PHROG	phrog_1271	HNH endonuclease	DNA, RNA and nucleotide metabolism
UHGV-0158551_26	UniRef90	UniRef90_A0A5M9ZVQ2	NA	NA
UHGV-0158551_26	Structural annotation	PF01844, PF09889, MF_00649	NA	NA
UHGV-0158551_27	KOfam	K07451	mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]	NA
UHGV-0158551_27	PHROG	phrog_333	HNH endonuclease	DNA, RNA and nucleotide metabolism
UHGV-0158551_27	UniRef90	UniRef90_A0A0A7I6T1	HNHc domain-containing protein	NA
UHGV-0158551_27	eggNOG-mapper	1692.BMAGN_1438	HNH endonuclease	NA
UHGV-0158551_27	Pfam	PF01844	HNH endonuclease	HNH
UHGV-0158551_27	COG	COG1403	5-methylcytosine-specific restriction endonuclease McrA	NA
UHGV-0158551_29	Structural annotation	PF06194	NA	NA
UHGV-0158551_37	eggNOG-mapper	445975.COLSTE_02319	NA	NA
UHGV-0158551_40	eggNOG-mapper	1435051.BMOU_1230	NA	NA
UHGV-0158551_41	UniRef90	UniRef90_A0A564VKW7	HTH cro/C1-type domain-containing protein	NA
UHGV-0158551_41	eggNOG-mapper	401473.BDP_1637	Cro/C1-type HTH DNA-binding domain	NA
UHGV-0158551_41	Pfam	PF13443	Cro/C1-type HTH DNA-binding domain	HTH_26
UHGV-0158551_42	KOfam	K15773	hipB; HTH-type transcriptional regulator / antitoxin HipB	NA
UHGV-0158551_42	PHROG	phrog_3	transcriptional repressor	transcription regulation
UHGV-0158551_42	UniRef90	UniRef90_A0A1X3A1X4	PbsX family transcriptional regulator	NA
UHGV-0158551_42	eggNOG-mapper	1435051.BMOU_1231	Helix-turn-helix XRE-family like proteins	NA
UHGV-0158551_42	Pfam	PF01381	Helix-turn-helix	HTH_3
UHGV-0158551_42	Structural annotation	PF13443, NF041951, COG1476	NA	NA
UHGV-0158551_43	PHROG	phrog_14333	NA	unknown function
UHGV-0158551_43	UniRef90	UniRef90_A0A6I1GPA6	Transcriptional regulator	NA
UHGV-0158551_43	eggNOG-mapper	547043.BIFPSEUDO_03942	NA	NA
UHGV-0158551_43	Pfam	PF13711	NA	DUF4160
UHGV-0158551_43	Structural annotation	PF13711	NA	NA
UHGV-0158551_44	PHROG	phrog_37898	NA	unknown function
UHGV-0158551_44	UniRef90	UniRef90_A0A2U2MTW0	NA	NA
UHGV-0158551_44	eggNOG-mapper	702459.BBPR_0014	NA	NA
UHGV-0158551_44	Pfam	PF10387	NA	DUF2442
UHGV-0158551_47	KOfam	K07491	rayT; REP-associated tyrosine transposase	NA
UHGV-0158551_47	PHROG	phrog_2577	transposase	integration and excision
UHGV-0158551_47	UniRef90	UniRef90_A0A833ILS3	IS200/IS605 family transposase	NA
UHGV-0158551_47	eggNOG-mapper	561180.BIFGAL_03405	Transposase IS200 like	NA
UHGV-0158551_47	Pfam	PF01797	Transposase IS200 like	Y1_Tnp
UHGV-0158551_47	NCBIFam	NF033573.1	IS200/IS605 family transposase	NA
UHGV-0158551_47	COG	COG1943	REP element-mobilizing transposase RayT	NA
UHGV-0158551_48	KOfam	K07496	K07496; putative transposase	NA
UHGV-0158551_48	PHROG	phrog_506	transposase	integration and excision
UHGV-0158551_48	UniRef90	UniRef90_A0A0S2MIL2	Transposase	NA
UHGV-0158551_48	eggNOG-mapper	398513.BBNG_00609	Helix-turn-helix domain	NA
UHGV-0158551_48	PADLOC	Cas14u	CAS-V-F; effector__SPE	CRISPR-CAS
UHGV-0158551_48	Pfam	PF12323	Helix-turn-helix domain	HTH_OrfB_IS605
UHGV-0158551_48	Pfam	PF01385	Probable transposase	OrfB_IS605
UHGV-0158551_48	Pfam	PF07282	Putative transposase DNA-binding domain	OrfB_Zn_ribbon
UHGV-0158551_48	NCBIFam	NF040570.1	RNA-guided endonuclease TnpB family protein	NA
UHGV-0158551_48	COG	COG0675	Transposase	NA
UHGV-0158551_48	Structural annotation	PF07282, PF01385, NF038281, COG0675	NA	NA
UHGV-0158551_49	KOfam	K01520	dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]	NA
UHGV-0158551_49	PHROG	phrog_135	dUTPase	DNA, RNA and nucleotide metabolism
UHGV-0158551_49	UniRef90	UniRef90_A7A5D6	dUTP diphosphatase	NA
UHGV-0158551_49	eggNOG-mapper	1238186.AOCN01000026_gene2061	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	NA
UHGV-0158551_49	Pfam	PF00692	dUTPase	dUTPase
UHGV-0158551_49	NCBIFam	NF001862.0	dUTP diphosphatase	NA
UHGV-0158551_49	COG	COG0756	dUTP pyrophosphatase (dUTPase)	NA
UHGV-0158551_49	Structural annotation	PF00692, MF_00116, NF001862, COG0756	NA	NA
UHGV-0158551_53	PHROG	phrog_908	NA	unknown function
UHGV-0158551_53	COG	COG2023	Ribonuclease P protein subunit RPR2	NA
UHGV-0158551_54	Structural annotation	PF13384	NA	NA
UHGV-0158551_56	PHROG	phrog_3641	NA	unknown function
UHGV-0158551_57	PHROG	phrog_2245	nucleoside triphosphate pyrophosphohydrolase	other
UHGV-0158551_57	UniRef90	UniRef90_A0A564VUK1	MazG domain-containing protein	NA
UHGV-0158551_57	eggNOG-mapper	1680.BADO_1259	NA	NA
UHGV-0158551_57	Pfam	PF03819	MazG nucleotide pyrophosphohydrolase domain	MazG
UHGV-0158551_57	Structural annotation	NF001611, COG1694	NA	NA
UHGV-0158551_58	eggNOG-mapper	78346.BRUM_0407	NA	NA
UHGV-0158551_58	Structural annotation	MF_00257, NF037951	NA	NA
UHGV-0158551_61	UniRef90	UniRef90_A0A1X3A9R1	Transposase	NA
UHGV-0158551_61	eggNOG-mapper	1435051.BMOU_0784	NA	NA
UHGV-0158551_63	Structural annotation	TIGR03655	NA	NA
UHGV-0158551_64	PHROG	phrog_21331	NA	unknown function
UHGV-0158551_64	UniRef90	UniRef90_A0A1X2YQU8	Peptidase	NA
UHGV-0158551_69	UniRef90	UniRef90_A0A0A7I2M5	Peptidase U32	NA
UHGV-0158551_70	PHROG	phrog_236	nucleotide kinase	other
UHGV-0158551_70	UniRef90	UniRef90_A0A1X3A1Z3	NA	NA
UHGV-0158551_70	eggNOG-mapper	1435051.BMOU_0788	NA	NA
UHGV-0158551_70	Pfam	PF11753	NA	DUF3310
UHGV-0158551_73	KOfam	K01520	dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]	NA
UHGV-0158551_73	PHROG	phrog_135	dUTPase	DNA, RNA and nucleotide metabolism
UHGV-0158551_73	UniRef90	UniRef90_R6P7Q1	dUTPase domain-containing protein	NA
UHGV-0158551_73	eggNOG-mapper	1151126.AQYI01000003_gene554	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	NA
UHGV-0158551_73	Pfam	PF00692	dUTPase	dUTPase
UHGV-0158551_73	NCBIFam	TIGR00576.1	dUTP diphosphatase	NA
UHGV-0158551_73	COG	COG0756	dUTP pyrophosphatase (dUTPase)	NA
UHGV-0158551_73	Structural annotation	PF00692, MF_00116, NF001862, COG0756	NA	NA
UHGV-0158551_74	KOfam	K13288	orn, REX2, REXO2; oligoribonuclease [EC:3.1.-.-]	NA
UHGV-0158551_74	UniRef90	UniRef90_A0A564VUG8	Oligoribonuclease	NA
UHGV-0158551_74	eggNOG-mapper	1688.BCUN_0417	3'-to-5' exoribonuclease specific for small oligoribonucleotides	NA
UHGV-0158551_74	COG	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	NA
UHGV-0158551_74	Structural annotation	PF13361, MF_00045, NF003765, COG1949	NA	NA
UHGV-0158551_75	eggNOG-mapper	1394176.AWUO01000014_gene674	NA	NA
UHGV-0158551_76	PHROG	phrog_270	replication initiation protein	DNA, RNA and nucleotide metabolism
UHGV-0158551_76	eggNOG-mapper	1437610.BREU_1410	NA	NA
UHGV-0158551_78	PHROG	phrog_244	RusA-like Holliday junction resolvase	DNA, RNA and nucleotide metabolism
UHGV-0158551_78	UniRef90	UniRef90_A0A1X2ZJJ9	NA	NA
UHGV-0158551_78	eggNOG-mapper	1193128.A200_07809	NA	NA
UHGV-0158551_78	Structural annotation	PF13588, COG1591	NA	NA
UHGV-0158551_79	KOfam	K03111	ssb; single-strand DNA-binding protein	NA
UHGV-0158551_79	PHROG	phrog_44	single strand DNA binding protein	DNA, RNA and nucleotide metabolism
UHGV-0158551_79	UniRef90	UniRef90_R6NTI6	Single-stranded DNA-binding protein	NA
UHGV-0158551_79	eggNOG-mapper	1680.BADO_1267	Single-strand binding protein family	NA
UHGV-0158551_79	Pfam	PF00436	Single-strand binding protein family	SSB
UHGV-0158551_79	COG	COG0629	Single-stranded DNA-binding protein	NA
UHGV-0158551_79	Structural annotation	PF00436, MF_00984, NF005851, COG0629	NA	NA
UHGV-0158551_81	PHROG	phrog_2780	RecT-like ssDNA annealing protein	DNA, RNA and nucleotide metabolism
UHGV-0158551_81	UniRef90	UniRef90_A0A0A7I2H6	Phage recombination protein Bet	NA
UHGV-0158551_81	eggNOG-mapper	1435051.BMOU_0794	RecT family	NA
UHGV-0158551_81	Pfam	PF03837	RecT family	RecT
UHGV-0158551_81	NCBIFam	TIGR01913.1	phage recombination protein Bet	NA
UHGV-0158551_81	COG	COG3723	Recombinational DNA repair protein RecT	NA
UHGV-0158551_81	Structural annotation	PF03837, TIGR01913, COG3723	NA	NA
UHGV-0158551_82	eggNOG-mapper	78346.BRUM_0411	NA	NA
UHGV-0158551_83	KOfam	K04074	divIVA; cell division initiation protein	NA
UHGV-0158551_83	UniRef90	UniRef90_A0A564VUN2	Cell wall synthesis protein Wag31	NA
UHGV-0158551_83	Pfam	PF05103	DivIVA protein	DivIVA
UHGV-0158551_83	NCBIFam	TIGR03544.1	DivIVA domain-containing protein	NA
UHGV-0158551_83	COG	COG3599	Cell division septum initiation protein DivIVA, interacts with FtsZ and MinD	NA
UHGV-0158551_83	Structural annotation	PF05103, MF_02011, NF010725	NA	NA
UHGV-0158551_85	PHROG	phrog_774	NA	unknown function
UHGV-0158551_87	KOfam	K07741	antB; anti-repressor protein	NA
UHGV-0158551_87	PHROG	phrog_130	anti-repressor Ant	transcription regulation
UHGV-0158551_87	UniRef90	UniRef90_A7A2N3	BRO family, N-terminal domain protein	NA
UHGV-0158551_87	eggNOG-mapper	78345.BMERY_0904	BRO family, N-terminal domain	NA
UHGV-0158551_87	Pfam	PF02498	BRO family, N-terminal domain	Bro-N
UHGV-0158551_87	Pfam	PF03374	Phage antirepressor protein KilAC domain	ANT
UHGV-0158551_87	COG	COG3617	Prophage antirepressor	NA
UHGV-0158551_87	Structural annotation	PF03374, PF10547, TIGR02681, COG3617	NA	NA
UHGV-0158551_88	KOfam	K21919	KCTD9; BTB/POZ domain-containing protein KCTD9	NA
UHGV-0158551_88	PHROG	phrog_9562	NA	unknown function
UHGV-0158551_88	UniRef90	UniRef90_A0A1X3A218	Pentapeptide repeat protein	NA
UHGV-0158551_88	eggNOG-mapper	1235799.C818_02571	Pentapeptide repeats (9 copies)	NA
UHGV-0158551_88	Pfam	PF00805	Pentapeptide repeats (8 copies)	Pentapeptide
UHGV-0158551_88	Pfam	PF19062	NA	DUF5758
UHGV-0158551_88	COG	COG1357	NA	NA
UHGV-0158551_88	Structural annotation	PF19062, PF13599, NF000420	NA	NA
UHGV-0158551_89	PHROG	phrog_9103	transcriptional repressor	transcription regulation
UHGV-0158551_89	UniRef90	UniRef90_A0A0A7I2H4	XRE family transcriptional regulator	NA
UHGV-0158551_89	eggNOG-mapper	1151126.AQYI01000007_gene1567	NA	NA
UHGV-0158551_89	Structural annotation	PF20432, NF000090, COG1476	NA	NA
UHGV-0158551_90	PHROG	phrog_16278	HTH DNA binding protein	DNA, RNA and nucleotide metabolism
UHGV-0158551_90	UniRef90	UniRef90_A0A1X2ZGN8	DNA-binding protein	NA
UHGV-0158551_90	eggNOG-mapper	1437605.BACT_1107	NA	NA
UHGV-0158551_90	Structural annotation	PF13560, MF_00535, NF041677, COG3655	NA	NA
UHGV-0158551_91	PHROG	phrog_87	metallo-protease	other
UHGV-0158551_91	UniRef90	UniRef90_A7A2N7	Peptidase_M78 domain-containing protein	NA
UHGV-0158551_91	eggNOG-mapper	78346.BRUM_0422	NA	NA
UHGV-0158551_91	Pfam	PF06114	IrrE N-terminal-like domain	Peptidase_M78
UHGV-0158551_91	Structural annotation	PF06114, COG2856	NA	NA
UHGV-0158551_93	KOfam	K00560	thyA, TYMS; thymidylate synthase [EC:2.1.1.45]	NA
UHGV-0158551_93	PHROG	phrog_160	thymidylate synthase	DNA, RNA and nucleotide metabolism
UHGV-0158551_93	UniRef90	UniRef90_A0A564VW46	Thymidylate synthase	NA
UHGV-0158551_93	eggNOG-mapper	35760.BCHO_0602	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	NA
UHGV-0158551_93	Pfam	PF00303	Thymidylate synthase	Thymidylat_synt
UHGV-0158551_93	NCBIFam	NF002497.0	thymidylate synthase	NA
UHGV-0158551_93	COG	COG0207	Thymidylate synthase	NA
UHGV-0158551_93	HAMAP	MF_00008	Thymidylate synthase [thyA]	NA
UHGV-0158551_93	Structural annotation	PF00303, MF_00008, NF002497, COG0207	NA	NA