| UHGV-0208331_1 | PHROG | phrog_1271 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0208331_1 | UniRef90 | UniRef90_UPI0014858467 | HNH endonuclease | NA |
| UHGV-0208331_1 | eggNOG-mapper | 634956.Geoth_0783 | HNH endonuclease | NA |
| UHGV-0208331_1 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0208331_1 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0208331_2 | PHROG | phrog_119 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0208331_2 | UniRef90 | UniRef90_UPI000543E00A | HNH endonuclease | NA |
| UHGV-0208331_2 | eggNOG-mapper | 768486.EHR_09545 | HNH nucleases | NA |
| UHGV-0208331_2 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0208331_4 | PHROG | phrog_9079 | NA | unknown function |
| UHGV-0208331_4 | eggNOG-mapper | 445973.CLOBAR_02450 | NA | NA |
| UHGV-0208331_5 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0208331_5 | UniRef90 | UniRef90_UPI0007BBAD29 | transcriptional regulator | NA |
| UHGV-0208331_5 | eggNOG-mapper | 1151292.QEW_0398 | sigma factor activity | NA |
| UHGV-0208331_5 | COG | COG1191 | DNA-directed RNA polymerase specialized sigma subunit | NA |
| UHGV-0208331_5 | Structural annotation | PF05263, TIGR01636 | NA | NA |
| UHGV-0208331_6 | PHROG | phrog_1485 | NA | unknown function |
| UHGV-0208331_6 | UniRef90 | UniRef90_UPI001105E44C | nucleotide modification associated domain-containing protein | NA |
| UHGV-0208331_6 | eggNOG-mapper | 1121871.AUAT01000002_gene1368 | NA | NA |
| UHGV-0208331_6 | Pfam | PF07659 | Nucleotide modification associated domain 1 | DUF1599 |
| UHGV-0208331_9 | PHROG | phrog_98 | NA | unknown function |
| UHGV-0208331_9 | UniRef90 | UniRef90_A0A1C5YXI2 | YopX protein | NA |
| UHGV-0208331_9 | eggNOG-mapper | 768726.HMPREF9178_1074 | YopX protein | NA |
| UHGV-0208331_9 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-0208331_9 | NCBIFam | TIGR01671.1 | phage conserved hypothetical protein TIGR01671 | NA |
| UHGV-0208331_9 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-0208331_12 | PHROG | phrog_2245 | nucleoside triphosphate pyrophosphohydrolase | other |
| UHGV-0208331_12 | UniRef90 | UniRef90_A0A373NRP8 | MazG domain-containing protein | NA |
| UHGV-0208331_12 | eggNOG-mapper | 1680.BADO_1259 | NA | NA |
| UHGV-0208331_12 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-0208331_12 | Structural annotation | PF12643, MF_01020, TIGR03188, COG0140 | NA | NA |
| UHGV-0208331_13 | Structural annotation | PF18482 | NA | NA |
| UHGV-0208331_15 | Pfam | PF04545 | Sigma-70, region 4 | Sigma70_r4 |
| UHGV-0208331_16 | KOfam | K03091 | sigH; RNA polymerase sporulation-specific sigma factor | NA |
| UHGV-0208331_16 | PHROG | phrog_351 | RNA polymerase sigma factor | transcription regulation |
| UHGV-0208331_16 | UniRef90 | UniRef90_UPI0014852BBC | sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-0208331_16 | eggNOG-mapper | 1410622.JNKY01000017_gene623 | Sigma-70 region 2 | NA |
| UHGV-0208331_16 | Pfam | PF04542 | Sigma-70 region 2 | Sigma70_r2 |
| UHGV-0208331_16 | NCBIFam | TIGR02937.1 | sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-0208331_16 | COG | COG1595 | DNA-directed RNA polymerase specialized sigma subunit, sigma24 family | NA |
| UHGV-0208331_19 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0208331_19 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0208331_19 | UniRef90 | UniRef90_UPI0011060A1D | single-stranded DNA-binding protein | NA |
| UHGV-0208331_19 | eggNOG-mapper | 445973.CLOBAR_00026 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-0208331_19 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0208331_19 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0208331_19 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0208331_19 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0208331_19 | Structural annotation | PF00436, MF_00984, NF005242, COG0629 | NA | NA |
| UHGV-0208331_21 | PHROG | phrog_5164 | NA | unknown function |
| UHGV-0208331_21 | Structural annotation | PF06892 | NA | NA |
| UHGV-0208331_23 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0208331_23 | PHROG | phrog_130 | anti-repressor Ant | transcription regulation |
| UHGV-0208331_23 | UniRef90 | UniRef90_UPI001AE15354 | phage antirepressor KilAC domain-containing protein | NA |
| UHGV-0208331_23 | eggNOG-mapper | 1415775.U729_2580 | BRO family, N-terminal domain | NA |
| UHGV-0208331_23 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-0208331_23 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0208331_23 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-0208331_23 | Structural annotation | PF02498, PF03374, TIGR02681, COG3617 | NA | NA |
| UHGV-0208331_24 | PHROG | phrog_1974 | NA | unknown function |
| UHGV-0208331_24 | UniRef90 | UniRef90_A0A371ISD9 | Nucleoid-associated protein | NA |
| UHGV-0208331_24 | eggNOG-mapper | 1301100.HG529375_gene4038 | 37-kD nucleoid-associated bacterial protein | NA |
| UHGV-0208331_24 | Pfam | PF04245 | 37-kD nucleoid-associated bacterial protein | NA37 |
| UHGV-0208331_24 | COG | COG3081 | dsDNA-binding nucleoid-associated protein YejK/NdpA | NA |
| UHGV-0208331_24 | Structural annotation | PF04245, MF_00730, NF001557, COG3081 | NA | NA |
| UHGV-0208331_25 | PHROG | phrog_824 | NA | unknown function |
| UHGV-0208331_25 | UniRef90 | UniRef90_UPI001105A33E | VRR-NUC domain-containing protein | NA |
| UHGV-0208331_25 | eggNOG-mapper | 411468.CLOSCI_00556 | VRR_NUC | NA |
| UHGV-0208331_25 | Pfam | PF08774 | VRR-NUC domain | VRR_NUC |
| UHGV-0208331_26 | PHROG | phrog_3584 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0208331_26 | UniRef90 | UniRef90_A0A1I5LZL1 | Relaxase/Mobilisation nuclease domain-containing protein | NA |
| UHGV-0208331_26 | eggNOG-mapper | 1196322.A370_05744 | NA | NA |
| UHGV-0208331_26 | Structural annotation | PF21578 | NA | NA |
| UHGV-0208331_28 | UniRef90 | UniRef90_UPI001105B88F | Rho termination factor N-terminal domain-containing protein | NA |
| UHGV-0208331_28 | Pfam | PF07498 | Rho termination factor, N-terminal domain | Rho_N |
| UHGV-0208331_31 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-0208331_31 | PHROG | phrog_2967 | transcriptional regulator | transcription regulation |
| UHGV-0208331_31 | UniRef90 | UniRef90_UPI0011061316 | helix-turn-helix domain-containing protein | NA |
| UHGV-0208331_31 | eggNOG-mapper | 411468.CLOSCI_01457 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0208331_31 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0208331_31 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0208331_31 | Structural annotation | PF01381, MF_00535, NF007257, COG1476 | NA | NA |
| UHGV-0208331_33 | KOfam | K07727 | K07727; putative transcriptional regulator | NA |
| UHGV-0208331_33 | PHROG | phrog_3 | transcriptional repressor | transcription regulation |
| UHGV-0208331_33 | UniRef90 | UniRef90_UPI0011069CE3 | helix-turn-helix domain-containing protein | NA |
| UHGV-0208331_33 | eggNOG-mapper | 742741.HMPREF9475_00399 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0208331_33 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0208331_33 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0208331_34 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-0208331_34 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-0208331_34 | UniRef90 | UniRef90_UPI0011073ABB | recombinase family protein | NA |
| UHGV-0208331_34 | eggNOG-mapper | 1151292.QEW_0309 | Resolvase, N terminal domain | NA |
| UHGV-0208331_34 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-0208331_34 | Pfam | PF07508 | Recombinase | Recombinase |
| UHGV-0208331_34 | Pfam | PF13408 | Recombinase zinc beta ribbon domain | Zn_ribbon_recom |
| UHGV-0208331_34 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-0208331_34 | Structural annotation | PF00239, PF07508, NF041201, COG1961 | NA | NA |
| UHGV-0208331_35 | KOfam | K03466 | ftsK, spoIIIE; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family | NA |
| UHGV-0208331_35 | PHROG | phrog_1358 | FtsK/SpoIIIE-like protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-0208331_35 | UniRef90 | UniRef90_A0A267MQD1 | FtsK domain-containing protein | NA |
| UHGV-0208331_35 | eggNOG-mapper | 1463900.JOIX01000030_gene4772 | NA | NA |
| UHGV-0208331_35 | PADLOC | SspH_00004 | SspH | SSP |
| UHGV-0208331_35 | Pfam | PF01580 | FtsK/SpoIIIE family | FtsK_SpoIIIE |
| UHGV-0208331_35 | COG | COG1674 | DNA segregation ATPase FtsK/SpoIIIE or related protein | NA |
| UHGV-0208331_35 | Structural annotation | PF01580, MF_01836, NF041214, COG0433 | NA | NA |
| UHGV-0208331_36 | PHROG | phrog_9996 | NA | unknown function |
| UHGV-0208331_36 | UniRef90 | UniRef90_UPI0011071500 | replication-relaxation family protein | NA |
| UHGV-0208331_36 | Pfam | PF13814 | Replication-relaxation | Replic_Relax |
| UHGV-0208331_36 | Structural annotation | PF13814, MF_01819, NF041423, COG1733 | NA | NA |
| UHGV-0208331_37 | PHROG | phrog_33044 | NA | unknown function |
| UHGV-0208331_38 | PHROG | phrog_2329 | NA | unknown function |
| UHGV-0208331_38 | UniRef90 | UniRef90_UPI001A21AB60 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | NA |
| UHGV-0208331_38 | eggNOG-mapper | 1292035.H476_0264 | NA | NA |
| UHGV-0208331_38 | Structural annotation | PF04014, NF008463, COG2336 | NA | NA |
| UHGV-0208331_40 | KOfam | K01448 | amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0208331_40 | PHROG | phrog_435 | endolysin | lysis |
| UHGV-0208331_40 | UniRef90 | UniRef90_UPI001106ED5F | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0208331_40 | eggNOG-mapper | 445973.CLOBAR_01731 | Ami_3 | NA |
| UHGV-0208331_40 | Pfam | PF01520 | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
| UHGV-0208331_40 | Pfam | PF19087 | NA | DUF5776 |
| UHGV-0208331_40 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0208331_40 | Structural annotation | PF01520, PF19087, TIGR02883, COG0860, COG4991 | NA | NA |
| UHGV-0208331_41 | PHROG | phrog_962 | holin | lysis |
| UHGV-0208331_41 | UniRef90 | UniRef90_UPI000983D253 | phage holin | NA |
| UHGV-0208331_41 | eggNOG-mapper | 1391647.AVSV01000003_gene1694 | COG5546 Small integral membrane protein | NA |
| UHGV-0208331_41 | Pfam | PF04531 | Bacteriophage holin | Phage_holin_1 |
| UHGV-0208331_41 | COG | COG5546 | NA | NA |
| UHGV-0208331_42 | PHROG | phrog_1193 | hemolysin | other |
| UHGV-0208331_42 | UniRef90 | UniRef90_UPI0018AB0AA6 | hemolysin XhlA family protein | NA |
| UHGV-0208331_42 | eggNOG-mapper | 445335.CBN_3060 | Haemolysin XhlA | NA |
| UHGV-0208331_42 | Pfam | PF10779 | Haemolysin XhlA | XhlA |
| UHGV-0208331_43 | UniRef90 | UniRef90_A0A6L5XGX1 | FAD-dependent oxidoreductase | NA |
| UHGV-0208331_43 | eggNOG-mapper | 411477.PARMER_00703 | FAD dependent oxidoreductase | NA |
| UHGV-0208331_43 | Pfam | PF12831 | FAD dependent oxidoreductase | FAD_oxidored |
| UHGV-0208331_43 | COG | COG1233 | Phytoene dehydrogenase-related protein | NA |
| UHGV-0208331_45 | KOfam | K11062 | entD; probable enterotoxin D | NA |
| UHGV-0208331_45 | PHROG | phrog_7043 | tail protein | tail |
| UHGV-0208331_45 | UniRef90 | UniRef90_UPI0011CA3AC4 | SH3 domain-containing protein | NA |
| UHGV-0208331_45 | eggNOG-mapper | 1292035.H476_1004 | Prophage endopeptidase tail | NA |
| UHGV-0208331_45 | Pfam | PF06605 | Prophage endopeptidase tail | Prophage_tail |
| UHGV-0208331_45 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-0208331_45 | NCBIFam | TIGR01665.1 | phage tail spike protein | NA |
| UHGV-0208331_45 | COG | COG4926 | Phage-related protein | NA |
| UHGV-0208331_45 | Structural annotation | PF14594, PF08239, PF19081, PF13229, TIGR01665, NF040678, COG4926, COG4991, COG0791 | NA | NA |
| UHGV-0208331_46 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0208331_46 | UniRef90 | UniRef90_A0A1C5VG03 | Phage-related protein | NA |
| UHGV-0208331_46 | eggNOG-mapper | 573061.Clocel_3532 | tail component | NA |
| UHGV-0208331_46 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0208331_46 | Structural annotation | PF20195, TIGR01633, COG4722 | NA | NA |
| UHGV-0208331_47 | KOfam | K06240 | LAMA3_5; laminin, alpha 3/5 | NA |
| UHGV-0208331_47 | PHROG | phrog_1272 | tail length tape measure protein | tail |
| UHGV-0208331_47 | UniRef90 | UniRef90_UPI0011074901 | phage tail tape measure protein | NA |
| UHGV-0208331_47 | eggNOG-mapper | 397290.C810_00429 | Phage-related minor tail protein | NA |
| UHGV-0208331_47 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0208331_47 | COG | COG5280 | Phage-related minor tail protein | NA |
| UHGV-0208331_47 | Structural annotation | PF10145, TIGR01760, COG5280 | NA | NA |
| UHGV-0208331_48 | eggNOG-mapper | 1121866.AUGK01000006_gene886 | NA | NA |
| UHGV-0208331_49 | UniRef90 | UniRef90_A0A316S919 | Phage tail protein | NA |
| UHGV-0208331_49 | eggNOG-mapper | 1384484.AEQU_1175 | NA | NA |
| UHGV-0208331_49 | Structural annotation | PF04630, TIGR01603, COG5437 | NA | NA |
| UHGV-0208331_50 | PHROG | phrog_5509 | neck protein | connector |
| UHGV-0208331_50 | eggNOG-mapper | 936140.AEOT01000014_gene1361 | NA | NA |
| UHGV-0208331_50 | Structural annotation | TIGR01725, COG5005 | NA | NA |
| UHGV-0208331_51 | Structural annotation | PF05657, COG3167 | NA | NA |
| UHGV-0208331_52 | PHROG | phrog_5635 | head-tail adaptor | connector |
| UHGV-0208331_52 | UniRef90 | UniRef90_UPI0011070497 | phage head closure protein | NA |
| UHGV-0208331_52 | eggNOG-mapper | 1220589.CD32_01710 | NA | NA |
| UHGV-0208331_52 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-0208331_52 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-0208331_53 | PHROG | phrog_749 | NA | unknown function |
| UHGV-0208331_53 | UniRef90 | UniRef90_A0A1I3QJG6 | Phage gp6-like head-tail connector protein | NA |
| UHGV-0208331_54 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0208331_54 | UniRef90 | UniRef90_UPI001107332E | phage major capsid protein | NA |
| UHGV-0208331_54 | eggNOG-mapper | 349161.Dred_2604 | Phage capsid family | NA |
| UHGV-0208331_54 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0208331_54 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0208331_54 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0208331_54 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0208331_55 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-0208331_55 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-0208331_55 | UniRef90 | UniRef90_UPI00110724D9 | Clp protease ClpP | NA |
| UHGV-0208331_55 | eggNOG-mapper | 1232452.BAIB02000007_gene1626 | Belongs to the peptidase S14 family | NA |
| UHGV-0208331_55 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-0208331_55 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-0208331_55 | Structural annotation | PF00574, MF_00444, NF011090, COG0740 | NA | NA |
| UHGV-0208331_56 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-0208331_56 | UniRef90 | UniRef90_UPI00148519DF | phage portal protein | NA |
| UHGV-0208331_56 | eggNOG-mapper | 349161.Dred_2606 | Phage portal protein, HK97 family | NA |
| UHGV-0208331_56 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-0208331_56 | NCBIFam | TIGR01537.1 | phage portal protein | NA |
| UHGV-0208331_56 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-0208331_56 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0208331_57 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-0208331_57 | UniRef90 | UniRef90_UPI0011061D03 | terminase large subunit | NA |
| UHGV-0208331_57 | eggNOG-mapper | 1211817.CCAT010000053_gene2129 | Phage Terminase | NA |
| UHGV-0208331_57 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-0208331_57 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-0208331_57 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-0208331_57 | Structural annotation | PF20441, PF03354, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0208331_58 | PHROG | phrog_83 | terminase small subunit | head and packaging |
| UHGV-0208331_58 | UniRef90 | UniRef90_UPI0003D5A199 | phage terminase small subunit P27 family | NA |
| UHGV-0208331_58 | eggNOG-mapper | 1121342.AUCO01000002_gene887 | Phage terminase, small subunit | NA |
| UHGV-0208331_58 | Pfam | PF05119 | Phage terminase, small subunit | Terminase_4 |
| UHGV-0208331_58 | NCBIFam | TIGR01558.1 | phage terminase small subunit P27 family | NA |
| UHGV-0208331_58 | COG | COG3747 | Phage terminase, small subunit | NA |