| UHGV-0374101_1 | PHROG | phrog_4402 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0374101_1 | UniRef90 | UniRef90_A0A0H5Q331 | Rep_3 domain-containing protein | NA |
| UHGV-0374101_1 | eggNOG-mapper | 999413.HMPREF1094_04438 | Initiator Replication protein | NA |
| UHGV-0374101_1 | Pfam | PF01051 | Initiator Replication protein, WH1 | Rep3_N |
| UHGV-0374101_1 | Pfam | PF21205 | Initiator Rep protein, WH2 | Rep3_C |
| UHGV-0374101_1 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-0374101_1 | Structural annotation | PF01051, PF21205, NF038290, COG5527 | NA | NA |
| UHGV-0374101_2 | UniRef90 | UniRef90_A0A2A7B6N3 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0374101_2 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0374101_2 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0374101_2 | Structural annotation | PF13560, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0374101_6 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0374101_6 | UniRef90 | UniRef90_A0A373XY93 | XRE family transcriptional regulator | NA |
| UHGV-0374101_6 | eggNOG-mapper | 665956.HMPREF1032_02614 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-0374101_6 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0374101_6 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0374101_7 | UniRef90 | UniRef90_A0A7X1LWA7 | XRE family transcriptional regulator | NA |
| UHGV-0374101_7 | eggNOG-mapper | 428125.CLOLEP_02737 | NA | NA |
| UHGV-0374101_7 | Structural annotation | TIGR03070 | NA | NA |
| UHGV-0374101_8 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0374101_8 | PHROG | phrog_130 | anti-repressor Ant | transcription regulation |
| UHGV-0374101_8 | UniRef90 | UniRef90_R5ANG2 | Phage antirepressor protein | NA |
| UHGV-0374101_8 | eggNOG-mapper | 1589751.A0A0C5AEJ9_9CAUD | DNA binding | NA |
| UHGV-0374101_8 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-0374101_8 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0374101_8 | Structural annotation | PF03374, PF02498, TIGR02681, COG3645 | NA | NA |
| UHGV-0374101_10 | Structural annotation | TIGR03826 | NA | NA |
| UHGV-0374101_11 | eggNOG-mapper | 760568.Desku_0919 | NA | NA |
| UHGV-0374101_11 | Structural annotation | PF03787, TIGR02581, COG1604 | NA | NA |
| UHGV-0374101_13 | Structural annotation | PF14143 | NA | NA |
| UHGV-0374101_14 | KOfam | K07738 | nrdR; transcriptional repressor NrdR | NA |
| UHGV-0374101_14 | eggNOG-mapper | 1410633.JHWR01000008_gene1673 | Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes | NA |
| UHGV-0374101_14 | COG | COG1327 | Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains | NA |
| UHGV-0374101_14 | Structural annotation | PF04606, NF007241 | NA | NA |
| UHGV-0374101_16 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0374101_16 | UniRef90 | UniRef90_E2ZNS9 | Erf family protein | NA |
| UHGV-0374101_16 | eggNOG-mapper | 748224.HMPREF9436_03360 | ERF superfamily | NA |
| UHGV-0374101_16 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-0374101_16 | Structural annotation | PF04404, COG4712 | NA | NA |
| UHGV-0374101_17 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0374101_17 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0374101_17 | UniRef90 | UniRef90_A0A6N7TNV3 | Single-stranded DNA-binding protein | NA |
| UHGV-0374101_17 | eggNOG-mapper | 748224.HMPREF9436_03359 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-0374101_17 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0374101_17 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0374101_17 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0374101_17 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0374101_17 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0374101_18 | PHROG | phrog_28936 | NA | unknown function |
| UHGV-0374101_18 | eggNOG-mapper | 573061.Clocel_3563 | NA | NA |
| UHGV-0374101_18 | Structural annotation | PF11645, MF_01490, NF040854 | NA | NA |
| UHGV-0374101_19 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0374101_19 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0374101_19 | UniRef90 | UniRef90_D4JYK0 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0374101_19 | eggNOG-mapper | 718252.FP2_16350 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-0374101_19 | PADLOC | oMTase_00004 | orphan methyltransferase | RM |
| UHGV-0374101_19 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0374101_19 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0374101_19 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0374101_19 | Structural annotation | PF00145, TIGR00675 | NA | NA |
| UHGV-0374101_21 | PHROG | phrog_35094 | NA | unknown function |
| UHGV-0374101_21 | eggNOG-mapper | 457424.BFAG_02409 | NA | NA |
| UHGV-0374101_23 | PHROG | phrog_843 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0374101_23 | UniRef90 | UniRef90_UPI001159D907 | Holliday junction resolvase RecU | NA |
| UHGV-0374101_23 | eggNOG-mapper | 929506.CbC4_1203 | Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation | NA |
| UHGV-0374101_23 | Structural annotation | PF03838, MF_00130, NF002581, COG3331 | NA | NA |
| UHGV-0374101_24 | Pfam | PF01155 | Hydrogenase/urease nickel incorporation, metallochaperone, hypA | HypA |
| UHGV-0374101_26 | Structural annotation | PF11998, COG5420 | NA | NA |
| UHGV-0374101_30 | Structural annotation | MF_00085, TIGR00037, COG0231 | NA | NA |
| UHGV-0374101_32 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0374101_33 | Structural annotation | PF16677 | NA | NA |
| UHGV-0374101_36 | UniRef90 | UniRef90_UPI0012DD33A2 | restriction endonuclease subunit M | NA |
| UHGV-0374101_36 | eggNOG-mapper | 936574.HMPREF1508_1307 | restriction endonuclease | NA |
| UHGV-0374101_36 | PADLOC | MTase_II_00176 | Type II methyltransferase | RM |
| UHGV-0374101_36 | COG | COG1002 | Type II restriction/modification system, endonuclease and methylase domains | NA |
| UHGV-0374101_46 | Structural annotation | NF041588 | NA | NA |
| UHGV-0374101_47 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0374101_47 | Structural annotation | NF041588 | NA | NA |
| UHGV-0374101_49 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-0374101_49 | Structural annotation | PF14354 | NA | NA |
| UHGV-0374101_50 | PHROG | phrog_15768 | NA | unknown function |
| UHGV-0374101_50 | UniRef90 | UniRef90_A0A6N7WKT0 | NA | NA |
| UHGV-0374101_50 | eggNOG-mapper | 748224.HMPREF9436_03357 | NA | NA |
| UHGV-0374101_50 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-0374101_50 | Structural annotation | PF19808 | NA | NA |
| UHGV-0374101_51 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0374101_51 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0374101_51 | UniRef90 | UniRef90_UPI001CBC4B63 | AAA family ATPase | NA |
| UHGV-0374101_51 | eggNOG-mapper | 1203606.HMPREF1526_01325 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-0374101_51 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0374101_51 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0374101_51 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0374101_52 | PHROG | phrog_419 | NA | unknown function |
| UHGV-0374101_52 | UniRef90 | UniRef90_A6MAI4 | Gp119 | NA |
| UHGV-0374101_52 | eggNOG-mapper | 768486.EHR_02665 | NA | NA |
| UHGV-0374101_52 | Structural annotation | PF14083 | NA | NA |
| UHGV-0374101_53 | PHROG | phrog_1709 | NA | unknown function |
| UHGV-0374101_53 | eggNOG-mapper | 500632.CLONEX_01053 | NA | NA |
| UHGV-0374101_55 | eggNOG-mapper | 1408437.JNJN01000010_gene1241 | NA | NA |
| UHGV-0374101_58 | PHROG | phrog_14275 | NA | unknown function |
| UHGV-0374101_58 | eggNOG-mapper | 1280676.AUJO01000001_gene2313 | NA | NA |
| UHGV-0374101_58 | Pfam | PF13240 | zinc-ribbon domain | zinc_ribbon_2 |
| UHGV-0374101_58 | Structural annotation | PF03843, MF_00984, TIGR00752, COG3065 | NA | NA |
| UHGV-0374101_59 | eggNOG-mapper | 1280696.ATVY01000001_gene3550 | NA | NA |
| UHGV-0374101_59 | Pfam | PF13240 | zinc-ribbon domain | zinc_ribbon_2 |
| UHGV-0374101_61 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0374101_61 | PHROG | phrog_373 | anti-repressor | transcription regulation |
| UHGV-0374101_61 | UniRef90 | UniRef90_A0A6N8HZA6 | AntA/AntB antirepressor | NA |
| UHGV-0374101_61 | eggNOG-mapper | 1567013.A0A0A7RVQ9_9CAUD | AntA/AntB antirepressor | NA |
| UHGV-0374101_61 | Pfam | PF08346 | AntA/AntB antirepressor | AntA |
| UHGV-0374101_61 | Pfam | PF10552 | ORF6C domain | ORF6C |
| UHGV-0374101_61 | Structural annotation | PF10552, PF08346, TIGR02681, COG3561 | NA | NA |
| UHGV-0374101_62 | Structural annotation | PF19807, NF041793, COG4877 | NA | NA |
| UHGV-0374101_64 | UniRef90 | UniRef90_A0A417DZ16 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0374101_64 | Structural annotation | PF20075, TIGR02612, COG1396 | NA | NA |
| UHGV-0374101_65 | KOfam | K14060 | pinR; putative DNA-invertase from lambdoid prophage Rac | NA |
| UHGV-0374101_65 | PHROG | phrog_125 | DNA invertase | DNA, RNA and nucleotide metabolism |
| UHGV-0374101_65 | UniRef90 | UniRef90_UPI001A9B5A42 | recombinase family protein | NA |
| UHGV-0374101_65 | eggNOG-mapper | 1443122.Z958_05795 | Resolvase, N terminal domain | NA |
| UHGV-0374101_65 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-0374101_65 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-0374101_65 | Structural annotation | PF00239, PF02796, NF009949, COG1961 | NA | NA |
| UHGV-0374101_67 | PHROG | phrog_38 | terminase large subunit | head and packaging |
| UHGV-0374101_67 | UniRef90 | UniRef90_UPI000419A6BC | phage terminase large subunit | NA |
| UHGV-0374101_67 | eggNOG-mapper | 1121866.AUGK01000003_gene1428 | chromosome segregation | NA |
| UHGV-0374101_67 | COG | COG5410 | NA | NA |
| UHGV-0374101_67 | Structural annotation | PF17289, PF02562, MF_04147, NF033889, COG5362, COG5410 | NA | NA |
| UHGV-0374101_69 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-0374101_69 | UniRef90 | UniRef90_A0A371ILT4 | Phage portal protein | NA |
| UHGV-0374101_69 | eggNOG-mapper | 1121866.AUGK01000003_gene1429 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-0374101_69 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-0374101_69 | Structural annotation | PF05133, MF_04120, TIGR01538, COG5511 | NA | NA |
| UHGV-0374101_72 | PHROG | phrog_29 | major head protein | head and packaging |
| UHGV-0374101_72 | UniRef90 | UniRef90_A0A7X5DZ98 | Phage capsid protein | NA |
| UHGV-0374101_72 | eggNOG-mapper | 476272.RUMHYD_01946 | Phage major capsid protein E | NA |
| UHGV-0374101_72 | Pfam | PF03864 | Phage major capsid protein E | Phage_cap_E |
| UHGV-0374101_72 | Structural annotation | PF03864, MF_04133, NF041162, COG4653 | NA | NA |
| UHGV-0374101_73 | UniRef90 | UniRef90_R6N215 | Phage QLRG family putative DNA packaging | NA |
| UHGV-0374101_73 | Structural annotation | TIGR01560 | NA | NA |
| UHGV-0374101_74 | eggNOG-mapper | 1298920.KI911353_gene2656 | NA | NA |
| UHGV-0374101_74 | Structural annotation | PF19586, TIGR01563, COG5614 | NA | NA |
| UHGV-0374101_76 | Structural annotation | PF06141, TIGR02367, COG3167 | NA | NA |
| UHGV-0374101_77 | PHROG | phrog_158 | major tail protein | tail |
| UHGV-0374101_77 | UniRef90 | UniRef90_UPI001D087591 | phage tail protein | NA |
| UHGV-0374101_77 | eggNOG-mapper | 1449343.JQLQ01000002_gene1514 | Phage tail tube protein, TTP | NA |
| UHGV-0374101_77 | Structural annotation | PF16463, TIGR02241, COG5437 | NA | NA |
| UHGV-0374101_78 | UniRef90 | UniRef90_A0A847YX95 | NA | NA |
| UHGV-0374101_78 | eggNOG-mapper | 1123263.AUKY01000015_gene1618 | NA | NA |
| UHGV-0374101_78 | Pfam | PF16478 | NA | DUF5055 |
| UHGV-0374101_78 | Structural annotation | PF16478 | NA | NA |
| UHGV-0374101_79 | eggNOG-mapper | 1121333.JMLH01000047_gene1011 | NA | NA |
| UHGV-0374101_80 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-0374101_80 | eggNOG-mapper | 1121866.AUGK01000003_gene1437 | phage tail tape measure protein | NA |
| UHGV-0374101_80 | COG | COG1280 | Threonine/homoserine/homoserine lactone efflux protein | NA |
| UHGV-0374101_81 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-0374101_81 | eggNOG-mapper | 665956.HMPREF1032_03629 | NA | NA |
| UHGV-0374101_81 | Pfam | PF20458 | NA | DUF6711 |
| UHGV-0374101_81 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-0374101_82 | PHROG | phrog_13879 | NA | unknown function |
| UHGV-0374101_82 | eggNOG-mapper | 1007103.AFHW01000096_gene3259 | NA | NA |
| UHGV-0374101_82 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-0374101_82 | Structural annotation | PF14594, PF19789, PF03256, PF09134, NF033848, COG3500, COG5156 | NA | NA |
| UHGV-0374101_83 | PHROG | phrog_18725 | NA | unknown function |
| UHGV-0374101_83 | UniRef90 | UniRef90_UPI001D0EF571 | Ig-like domain-containing protein | NA |
| UHGV-0374101_83 | eggNOG-mapper | 718252.FP2_14370 | domain, Protein | NA |
| UHGV-0374101_83 | COG | COG5492 | NA | NA |
| UHGV-0374101_83 | Structural annotation | PF15417, NF041539 | NA | NA |
| UHGV-0374101_84 | PHROG | phrog_5302 | tail protein | tail |
| UHGV-0374101_84 | UniRef90 | UniRef90_UPI001CBAF2B2 | carboxypeptidase-like regulatory domain-containing protein | NA |
| UHGV-0374101_84 | eggNOG-mapper | 1203606.HMPREF1526_00261 | cellulose 1,4-beta-cellobiosidase activity | NA |
| UHGV-0374101_84 | COG | COG5301 | Phage-related tail fiber protein | NA |
| UHGV-0374101_84 | Structural annotation | PF12985 | NA | NA |
| UHGV-0374101_88 | UniRef90 | UniRef90_A0A6A8KSZ5 | XkdX family protein | NA |
| UHGV-0374101_88 | eggNOG-mapper | 718252.FP2_16990 | Phage uncharacterised protein (Phage_XkdX) | NA |
| UHGV-0374101_88 | Pfam | PF09693 | Phage uncharacterised protein (Phage_XkdX) | Phage_XkdX |
| UHGV-0374101_88 | Structural annotation | PF09693 | NA | NA |
| UHGV-0374101_89 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-0374101_89 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-0374101_89 | UniRef90 | UniRef90_A0A564U0D3 | Autolytic lysozyme | NA |
| UHGV-0374101_89 | eggNOG-mapper | 718252.FP2_04890 | hydrolase, family 25 | NA |
| UHGV-0374101_89 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-0374101_89 | COG | COG3757 | Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family | NA |
| UHGV-0374101_89 | Structural annotation | PF01183, NF003812, COG3757 | NA | NA |
| UHGV-0374101_91 | PHROG | phrog_15303 | NA | unknown function |
| UHGV-0374101_93 | PHROG | phrog_5765 | NA | unknown function |
| UHGV-0374101_93 | UniRef90 | UniRef90_UPI001D0EF465 | BC1881 family protein | NA |
| UHGV-0374101_93 | eggNOG-mapper | 1095750.HMPREF9970_1008 | NA | NA |
| UHGV-0374101_93 | NCBIFam | NF033495.1 | BC1881 family protein | NA |
| UHGV-0374101_94 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-0374101_94 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0374101_94 | Structural annotation | PF01381, TIGR03070, COG1396 | NA | NA |
| UHGV-0374101_97 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0374101_97 | eggNOG-mapper | 1408437.JNJN01000043_gene803 | NA | NA |
| UHGV-0374101_98 | eggNOG-mapper | 658655.HMPREF0988_00916 | NA | NA |
| UHGV-0374101_99 | eggNOG-mapper | 1408437.JNJN01000043_gene801 | NA | NA |
| UHGV-0374101_101 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0374101_102 | Structural annotation | PF07878 | NA | NA |
| UHGV-0374101_103 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0374101_104 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-0374101_104 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-0374101_104 | UniRef90 | UniRef90_A0A1C6BS15 | Sporulation initiation inhibitor protein soj | NA |
| UHGV-0374101_104 | eggNOG-mapper | 1408423.JHYA01000021_gene392 | Cellulose biosynthesis protein BcsQ | NA |
| UHGV-0374101_104 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-0374101_104 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-0374101_104 | Structural annotation | PF13614, MF_00533, NF010443, COG1192 | NA | NA |
| UHGV-0374101_105 | PHROG | phrog_60 | NA | unknown function |
| UHGV-0374101_105 | UniRef90 | UniRef90_A0A316RLR0 | NA | NA |
| UHGV-0374101_105 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0374101_105 | Structural annotation | NF041588 | NA | NA |