| UHGV-0374815_2 | KOfam | K14059 | int; integrase | NA |
| UHGV-0374815_2 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0374815_2 | UniRef90 | UniRef90_UPI001F4C3C19 | tyrosine-type recombinase/integrase | NA |
| UHGV-0374815_2 | eggNOG-mapper | 580331.Thit_1365 | Belongs to the 'phage' integrase family | NA |
| UHGV-0374815_2 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-0374815_2 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0374815_2 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0374815_2 | Structural annotation | PF00589, PF13102, MF_01808, TIGR02224, COG4974 | NA | NA |
| UHGV-0374815_3 | PHROG | phrog_10091 | holin | lysis |
| UHGV-0374815_3 | UniRef90 | UniRef90_A0A3D2H1A4 | Phage holin | NA |
| UHGV-0374815_3 | eggNOG-mapper | 97139.C824_05950 | Bacteriophage holin | NA |
| UHGV-0374815_3 | Pfam | PF04531 | Bacteriophage holin | Phage_holin_1 |
| UHGV-0374815_3 | NCBIFam | TIGR01598.1 | phage holin | NA |
| UHGV-0374815_3 | COG | COG5546 | NA | NA |
| UHGV-0374815_3 | Structural annotation | COG5546 | NA | NA |
| UHGV-0374815_4 | PHROG | phrog_1863 | NA | unknown function |
| UHGV-0374815_4 | eggNOG-mapper | 1033740.CAEW01000026_gene549 | NA | NA |
| UHGV-0374815_5 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-0374815_5 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-0374815_5 | UniRef90 | UniRef90_A0A1Q6JJV0 | Methyltransferase | NA |
| UHGV-0374815_5 | eggNOG-mapper | 1232453.BAIF02000044_gene3483 | DNA methylase | NA |
| UHGV-0374815_5 | PADLOC | MTase_II_00107 | Type II methyltransferase | RM |
| UHGV-0374815_5 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-0374815_5 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-0374815_5 | Structural annotation | PF01555, MF_01872, NF010253, COG0863 | NA | NA |
| UHGV-0374815_6 | KOfam | K21470 | ycbB; L,D-transpeptidase YcbB | NA |
| UHGV-0374815_6 | PHROG | phrog_2649 | endolysin | lysis |
| UHGV-0374815_6 | UniRef90 | UniRef90_A0A3D2H1H5 | PG_binding_1 domain-containing protein | NA |
| UHGV-0374815_6 | eggNOG-mapper | 1120954.ATXE01000001_gene2057 | Caspase domain | NA |
| UHGV-0374815_6 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0374815_6 | COG | COG0810 | Periplasmic protein TonB, links inner and outer membranes | NA |
| UHGV-0374815_9 | PHROG | phrog_4912 | tail fiber assembly | tail |
| UHGV-0374815_9 | UniRef90 | UniRef90_UPI0011DCDC2D | phage tail assembly chaperone | NA |
| UHGV-0374815_9 | Pfam | PF16778 | Phage tail assembly chaperone protein | Phage_tail_APC |
| UHGV-0374815_9 | Structural annotation | PF16778 | NA | NA |
| UHGV-0374815_10 | KOfam | K00986 | ltrA; RNA-directed DNA polymerase [EC:2.7.7.49] | NA |
| UHGV-0374815_10 | PHROG | phrog_1423 | Reverse transcriptase | DNA, RNA and nucleotide metabolism |
| UHGV-0374815_10 | UniRef90 | UniRef90_R6GLF4 | Reverse transcriptase domain-containing protein | NA |
| UHGV-0374815_10 | eggNOG-mapper | 1160721.RBI_I01568 | Reverse transcriptase (RNA-dependent DNA polymerase) | NA |
| UHGV-0374815_10 | PADLOC | icity0040 | RT (reverse transcriptase) | CRISPR-CAS |
| UHGV-0374815_10 | Pfam | PF00078 | Reverse transcriptase (RNA-dependent DNA polymerase) | RVT_1 |
| UHGV-0374815_10 | COG | COG3344 | Retron-type reverse transcriptase | NA |
| UHGV-0374815_10 | Structural annotation | PF00078, MF_01390, TIGR04416, COG3344 | NA | NA |
| UHGV-0374815_11 | PHROG | phrog_3206 | Avd protein of DGR | DNA, RNA and nucleotide metabolism |
| UHGV-0374815_11 | eggNOG-mapper | 1519439.JPJG01000059_gene1941 | NA | NA |
| UHGV-0374815_11 | Structural annotation | PF05635, NF008911 | NA | NA |
| UHGV-0374815_12 | PHROG | phrog_19280 | NA | unknown function |
| UHGV-0374815_12 | UniRef90 | UniRef90_A0A3D2GZQ9 | NA | NA |
| UHGV-0374815_12 | eggNOG-mapper | 1226322.HMPREF1545_03571 | cellulose binding | NA |
| UHGV-0374815_12 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-0374815_12 | COG | COG4447 | NA | NA |
| UHGV-0374815_12 | Structural annotation | PF19789 | NA | NA |
| UHGV-0374815_13 | eggNOG-mapper | 1519439.JPJG01000060_gene1892 | Collagen triple helix repeat (20 copies) | NA |
| UHGV-0374815_13 | COG | COG3064 | Membrane protein TolA involved in colicin uptake | NA |
| UHGV-0374815_14 | PHROG | phrog_4311 | minor head protein | head and packaging |
| UHGV-0374815_14 | UniRef90 | UniRef90_A0A3D2H1J0 | Prophage_tail domain-containing protein | NA |
| UHGV-0374815_14 | eggNOG-mapper | 1033744.CAEL01000029_gene1269 | NA | NA |
| UHGV-0374815_14 | Pfam | PF06605 | Prophage endopeptidase tail | Prophage_tail |
| UHGV-0374815_14 | NCBIFam | TIGR01665.1 | phage tail spike protein | NA |
| UHGV-0374815_14 | COG | COG4926 | Phage-related protein | NA |
| UHGV-0374815_14 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-0374815_15 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0374815_15 | UniRef90 | UniRef90_UPI0018A952AB | phage tail family protein | NA |
| UHGV-0374815_15 | NCBIFam | TIGR01633.1 | distal tail protein Dit | NA |
| UHGV-0374815_15 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0374815_15 | Structural annotation | PF20753, PF20195, TIGR01633, COG4722 | NA | NA |
| UHGV-0374815_16 | PHROG | phrog_8462 | tail length tape measure protein | tail |
| UHGV-0374815_16 | eggNOG-mapper | 498761.HM1_2969 | nuclear chromosome segregation | NA |
| UHGV-0374815_16 | COG | COG5280 | Phage-related minor tail protein | NA |
| UHGV-0374815_16 | Structural annotation | TIGR01760 | NA | NA |
| UHGV-0374815_19 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-0374815_19 | UniRef90 | UniRef90_A0A6N9Q756 | Phage tail protein | NA |
| UHGV-0374815_19 | eggNOG-mapper | 1234664.AMRO01000024_gene1814 | phage major tail protein, phi13 family | NA |
| UHGV-0374815_19 | Pfam | PF04630 | Phage tail tube protein | Phage_TTP_1 |
| UHGV-0374815_19 | NCBIFam | TIGR01603.1 | major tail protein | NA |
| UHGV-0374815_19 | Structural annotation | PF04630, TIGR01603, COG3498 | NA | NA |
| UHGV-0374815_20 | Structural annotation | PF05657 | NA | NA |
| UHGV-0374815_21 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-0374815_21 | UniRef90 | UniRef90_A0A658JX18 | HK97 gp10 family phage protein | NA |
| UHGV-0374815_21 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-0374815_21 | NCBIFam | TIGR01725.1 | HK97-gp10 family putative phage morphogenesis protein | NA |
| UHGV-0374815_21 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-0374815_22 | PHROG | phrog_25 | head closure Hc1 | connector |
| UHGV-0374815_22 | UniRef90 | UniRef90_A0A2S6FUR7 | SPP1 family predicted phage head-tail adaptor | NA |
| UHGV-0374815_22 | eggNOG-mapper | 1408428.JNJP01000182_gene2411 | Phage head-tail joining protein | NA |
| UHGV-0374815_22 | Pfam | PF05521 | Phage head-tail joining protein | Phage_H_T_join |
| UHGV-0374815_22 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-0374815_22 | COG | COG5614 | Phage head-tail adaptor | NA |
| UHGV-0374815_22 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-0374815_23 | Structural annotation | PF05135, TIGR01560 | NA | NA |
| UHGV-0374815_25 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0374815_25 | UniRef90 | UniRef90_A0A3D2H6R2 | Phage major capsid protein | NA |
| UHGV-0374815_25 | eggNOG-mapper | 1007103.AFHW01000142_gene1299 | Phage capsid family | NA |
| UHGV-0374815_25 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0374815_25 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0374815_25 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0374815_25 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0374815_26 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-0374815_26 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-0374815_26 | UniRef90 | UniRef90_A0A3D2H4G5 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-0374815_26 | eggNOG-mapper | 994573.T472_0211340 | Belongs to the peptidase S14 family | NA |
| UHGV-0374815_26 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-0374815_26 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-0374815_26 | Structural annotation | PF00574, MF_00444, TIGR00493, COG0740 | NA | NA |
| UHGV-0374815_27 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-0374815_27 | UniRef90 | UniRef90_A0A3D2H236 | Phage portal protein | NA |
| UHGV-0374815_27 | eggNOG-mapper | 235909.GK0529 | Phage portal protein | NA |
| UHGV-0374815_27 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-0374815_27 | NCBIFam | TIGR01537.1 | phage portal protein | NA |
| UHGV-0374815_27 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-0374815_27 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0374815_28 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-0374815_28 | UniRef90 | UniRef90_A0A3D2H2V0 | Terminase large subunit | NA |
| UHGV-0374815_28 | eggNOG-mapper | 1295642.H839_15973 | Phage Terminase | NA |
| UHGV-0374815_28 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-0374815_28 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-0374815_28 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-0374815_28 | Structural annotation | PF20441, PF03354, MF_04145, TIGR01547, COG4626 | NA | NA |
| UHGV-0374815_29 | eggNOG-mapper | 189425.PGRAT_19340 | Phage terminase, small subunit | NA |
| UHGV-0374815_29 | Pfam | PF05119 | Phage terminase, small subunit | Terminase_4 |
| UHGV-0374815_30 | KOfam | K07451 | mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] | NA |
| UHGV-0374815_30 | PHROG | phrog_119 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0374815_30 | UniRef90 | UniRef90_A0A3D2H4J2 | Endonuclease | NA |
| UHGV-0374815_30 | eggNOG-mapper | 411465.PEPMIC_00028 | HNH nucleases | NA |
| UHGV-0374815_30 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0374815_30 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0374815_31 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0374815_31 | UniRef90 | UniRef90_A0A1Q6JK08 | Sigma70_r4 domain-containing protein | NA |
| UHGV-0374815_32 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0374815_32 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0374815_32 | UniRef90 | UniRef90_A0A3D2H4G4 | Single-stranded DNA-binding protein | NA |
| UHGV-0374815_32 | eggNOG-mapper | 555088.DealDRAFT_2203 | Single-stranded DNA-binding protein | NA |
| UHGV-0374815_32 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0374815_32 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0374815_32 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0374815_32 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0374815_32 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0374815_33 | UniRef90 | UniRef90_A0A3D2H2I1 | NA | NA |
| UHGV-0374815_33 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-0374815_33 | Structural annotation | PF19789 | NA | NA |
| UHGV-0374815_36 | PHROG | phrog_15609 | NA | unknown function |
| UHGV-0374815_36 | UniRef90 | UniRef90_A0A3D2H4F9 | HTH_ParB domain-containing protein | NA |
| UHGV-0374815_36 | eggNOG-mapper | 693746.OBV_25390 | NA | NA |
| UHGV-0374815_36 | Pfam | PF11300 | NA | DUF3102 |
| UHGV-0374815_36 | COG | COG2433 | Possible nuclease of RNase H fold, RuvC/YqgF family | NA |
| UHGV-0374815_36 | Structural annotation | PF11300, NF038070 | NA | NA |
| UHGV-0374815_39 | PHROG | phrog_6088 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-0374815_39 | UniRef90 | UniRef90_A0A5D3I7V8 | DNA primase | NA |
| UHGV-0374815_39 | eggNOG-mapper | 760568.Desku_3516 | DNA primase | NA |
| UHGV-0374815_39 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0374815_39 | Structural annotation | PF06048, PF01807, PF18662, PF19898, MF_00974, MF_00016, TIGR01391, NF011296, COG5519, COG0358 | NA | NA |
| UHGV-0374815_40 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0374815_41 | UniRef90 | UniRef90_A0A3D2H4I2 | HTH_17 domain-containing protein | NA |
| UHGV-0374815_41 | Pfam | PF12728 | Helix-turn-helix domain | HTH_17 |
| UHGV-0374815_41 | NCBIFam | TIGR01764.1 | excisionase family DNA-binding protein | NA |
| UHGV-0374815_42 | PHROG | phrog_6499 | transcriptional regulator | transcription regulation |
| UHGV-0374815_42 | UniRef90 | UniRef90_M8CV02 | Helix-turn-helix protein | NA |
| UHGV-0374815_42 | eggNOG-mapper | 1304880.JAGB01000002_gene2243 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0374815_42 | COG | COG1813 | Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains | NA |
| UHGV-0374815_43 | KOfam | K07729 | K07729; putative transcriptional regulator | NA |
| UHGV-0374815_43 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0374815_43 | UniRef90 | UniRef90_A0A3D2GZZ7 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0374815_43 | eggNOG-mapper | 1262449.CP6013_3687 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-0374815_43 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0374815_43 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0374815_43 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |