| UHGV-0386453_1 | PHROG | phrog_962 | holin | lysis |
| UHGV-0386453_1 | UniRef90 | UniRef90_A0A1C7FJG7 | Phage holin | NA |
| UHGV-0386453_1 | eggNOG-mapper | 1225805.J7KGX7_9CAUD | Bacteriophage holin | NA |
| UHGV-0386453_1 | Pfam | PF04531 | Bacteriophage holin | Phage_holin_1 |
| UHGV-0386453_1 | NCBIFam | TIGR01598.1 | phage holin | NA |
| UHGV-0386453_1 | Structural annotation | COG5546 | NA | NA |
| UHGV-0386453_2 | PHROG | phrog_21357 | endolysin | lysis |
| UHGV-0386453_2 | UniRef90 | UniRef90_A0A6I2R6Q1 | CHAP domain-containing protein | NA |
| UHGV-0386453_2 | eggNOG-mapper | 97139.C824_00684 | lysozyme activity | NA |
| UHGV-0386453_2 | Pfam | PF05257 | CHAP domain | CHAP |
| UHGV-0386453_2 | COG | COG1388 | LysM repeat | NA |
| UHGV-0386453_2 | Structural annotation | PF10030, TIGR02594, COG4322 | NA | NA |
| UHGV-0386453_3 | PHROG | phrog_37604 | NA | unknown function |
| UHGV-0386453_3 | eggNOG-mapper | 1232443.BAIA02000078_gene10 | NA | NA |
| UHGV-0386453_5 | PHROG | phrog_21765 | NA | unknown function |
| UHGV-0386453_5 | eggNOG-mapper | 665956.HMPREF1032_02937 | cellulose 1,4-beta-cellobiosidase activity | NA |
| UHGV-0386453_5 | COG | COG5301 | Phage-related tail fiber protein | NA |
| UHGV-0386453_7 | PHROG | phrog_15594 | NA | unknown function |
| UHGV-0386453_7 | eggNOG-mapper | 1118055.CAGU01000013_gene763 | NA | NA |
| UHGV-0386453_7 | Structural annotation | PF16640, TIGR04488 | NA | NA |
| UHGV-0386453_8 | UniRef90 | UniRef90_A0A8D9UHK2 | Chitin oligosaccharide deacetylase | NA |
| UHGV-0386453_8 | eggNOG-mapper | 1203606.HMPREF1526_01926 | NA | NA |
| UHGV-0386453_8 | Pfam | PF02839 | Carbohydrate-binding module family 5/12 | CBM_5_12 |
| UHGV-0386453_9 | eggNOG-mapper | 1297617.JPJD01000014_gene875 | NA | NA |
| UHGV-0386453_10 | PHROG | phrog_10993 | Hoc-like head decoration | head and packaging |
| UHGV-0386453_10 | eggNOG-mapper | 1203606.HMPREF1526_01924 | NA | NA |
| UHGV-0386453_11 | PHROG | phrog_30508 | NA | unknown function |
| UHGV-0386453_12 | PHROG | phrog_521 | tail protein | tail |
| UHGV-0386453_12 | UniRef90 | UniRef90_UPI001A9C8D3A | NA | NA |
| UHGV-0386453_12 | eggNOG-mapper | 742738.HMPREF9460_02532 | NA | NA |
| UHGV-0386453_12 | Pfam | PF10076 | Bacteriophage Mu-like, Gp48 | Phage_Mu_Gp48 |
| UHGV-0386453_12 | COG | COG4385 | Bacteriophage P2-related tail formation protein | NA |
| UHGV-0386453_12 | Structural annotation | PF10076, PF12571, TIGR02242, COG3778 | NA | NA |
| UHGV-0386453_13 | PHROG | phrog_6 | baseplate protein | tail |
| UHGV-0386453_13 | UniRef90 | UniRef90_A0A096B737 | Baseplate_J domain-containing protein | NA |
| UHGV-0386453_13 | eggNOG-mapper | 742738.HMPREF9460_02531 | Baseplate J-like protein | NA |
| UHGV-0386453_13 | Pfam | PF04865 | Baseplate J-like protein | Baseplate_J |
| UHGV-0386453_13 | COG | COG3299 | NA | NA |
| UHGV-0386453_13 | Structural annotation | PF04865, PF21379, MF_04102, TIGR02243, COG3299 | NA | NA |
| UHGV-0386453_14 | PHROG | phrog_120 | baseplate protein | tail |
| UHGV-0386453_14 | UniRef90 | UniRef90_UPI00164C7E68 | NA | NA |
| UHGV-0386453_14 | eggNOG-mapper | 742738.HMPREF9460_02530 | NA | NA |
| UHGV-0386453_14 | Pfam | PF10934 | NA | DUF2634 |
| UHGV-0386453_14 | COG | COG3628 | Phage baseplate assembly protein W | NA |
| UHGV-0386453_14 | Structural annotation | PF10934, TIGR03357, COG3628 | NA | NA |
| UHGV-0386453_15 | PHROG | phrog_579 | NA | unknown function |
| UHGV-0386453_15 | UniRef90 | UniRef90_UPI00164ADD64 | NA | NA |
| UHGV-0386453_15 | eggNOG-mapper | 743719.PaelaDRAFT_2414 | NA | NA |
| UHGV-0386453_15 | Pfam | PF10844 | NA | DUF2577 |
| UHGV-0386453_15 | Structural annotation | PF10844 | NA | NA |
| UHGV-0386453_16 | PHROG | phrog_400 | tail protein | tail |
| UHGV-0386453_16 | eggNOG-mapper | 742738.HMPREF9460_02528 | PFAM Phage late control gene D protein (GPD) | NA |
| UHGV-0386453_16 | COG | COG4193 | Beta- N-acetylglucosaminidase | NA |
| UHGV-0386453_16 | Structural annotation | PF14594, NF033848, COG3500 | NA | NA |
| UHGV-0386453_17 | PHROG | phrog_380 | endolysin | lysis |
| UHGV-0386453_17 | UniRef90 | UniRef90_UPI001C02B152 | LysM peptidoglycan-binding domain-containing protein | NA |
| UHGV-0386453_17 | eggNOG-mapper | 742738.HMPREF9460_02527 | LysM domain | NA |
| UHGV-0386453_17 | COG | COG1652 | Cytoplasmic potassium-binding protein Kbp/XkdP/YgaU, contains LysM domain | NA |
| UHGV-0386453_17 | Structural annotation | PF21821, TIGR02126, COG5437 | NA | NA |
| UHGV-0386453_18 | PHROG | phrog_1068 | tail length tape measure protein | tail |
| UHGV-0386453_18 | UniRef90 | UniRef90_UPI001AE00582 | tape measure protein | NA |
| UHGV-0386453_18 | eggNOG-mapper | 1121289.JHVL01000085_gene1569 | tape measure | NA |
| UHGV-0386453_18 | Pfam | PF20155 | Tape measure protein | TMP_3 |
| UHGV-0386453_18 | NCBIFam | TIGR02675.1 | tape measure protein | NA |
| UHGV-0386453_18 | COG | COG5281 | Phage-related minor tail protein | NA |
| UHGV-0386453_18 | Structural annotation | PF20155, TIGR01760, COG3941 | NA | NA |
| UHGV-0386453_19 | PHROG | phrog_28231 | NA | unknown function |
| UHGV-0386453_20 | PHROG | phrog_389 | tail protein XkdN-like | tail |
| UHGV-0386453_20 | UniRef90 | UniRef90_A0A1Y4BN58 | Phage portal protein | NA |
| UHGV-0386453_20 | eggNOG-mapper | 742738.HMPREF9460_02524 | Phage XkdN-like tail assembly chaperone protein, TAC | NA |
| UHGV-0386453_20 | Pfam | PF08890 | Phage XkdN-like tail assembly chaperone protein, TAC | Phage_TAC_5 |
| UHGV-0386453_20 | Structural annotation | PF08890, COG4518 | NA | NA |
| UHGV-0386453_21 | PHROG | phrog_365 | tail protein | tail |
| UHGV-0386453_21 | UniRef90 | UniRef90_UPI0002FED004 | phage tail tube protein | NA |
| UHGV-0386453_21 | eggNOG-mapper | 1007096.BAGW01000022_gene2654 | Phage tail tube protein | NA |
| UHGV-0386453_21 | Pfam | PF09393 | Phage tail tube protein | DUF2001 |
| UHGV-0386453_21 | Structural annotation | PF09393, TIGR02241, COG5437 | NA | NA |
| UHGV-0386453_22 | PHROG | phrog_279 | tail sheath | tail |
| UHGV-0386453_22 | UniRef90 | UniRef90_A0A1Y4L2W8 | Phage tail sheath protein | NA |
| UHGV-0386453_22 | eggNOG-mapper | 742738.HMPREF9460_02522 | Phage tail sheath C-terminal domain | NA |
| UHGV-0386453_22 | Pfam | PF17481 | Phage tail sheath protein beta-sandwich domain | Phage_sheath_1N |
| UHGV-0386453_22 | Pfam | PF04984 | Phage tail sheath protein subtilisin-like domain | Phage_sheath_1 |
| UHGV-0386453_22 | Pfam | PF17482 | Phage tail sheath C-terminal domain | Phage_sheath_1C |
| UHGV-0386453_22 | Structural annotation | PF17482, PF04984, PF17481, COG4386 | NA | NA |
| UHGV-0386453_23 | PHROG | phrog_30826 | NA | unknown function |
| UHGV-0386453_24 | PHROG | phrog_525 | NA | unknown function |
| UHGV-0386453_24 | Pfam | PF20765 | NA | DUF6838 |
| UHGV-0386453_24 | Structural annotation | PF20765, COG5003 | NA | NA |
| UHGV-0386453_25 | UniRef90 | UniRef90_UPI00164CB61C | HK97 gp10 family phage protein | NA |
| UHGV-0386453_25 | eggNOG-mapper | 398512.JQKC01000052_gene2665 | Bacteriophage HK97-gp10, putative tail-component | NA |
| UHGV-0386453_25 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-0386453_25 | Structural annotation | PF04883, TIGR01725, COG5005 | NA | NA |
| UHGV-0386453_26 | PHROG | phrog_615 | head-tail adaptor | connector |
| UHGV-0386453_26 | Structural annotation | PF12206, TIGR01563, COG5614 | NA | NA |
| UHGV-0386453_27 | PHROG | phrog_302 | virion structural protein | head and packaging |
| UHGV-0386453_27 | UniRef90 | UniRef90_UPI00164AB123 | NA | NA |
| UHGV-0386453_27 | eggNOG-mapper | 742738.HMPREF9460_02517 | NA | NA |
| UHGV-0386453_27 | Pfam | PF13262 | NA | DUF4054 |
| UHGV-0386453_27 | Structural annotation | PF13262 | NA | NA |
| UHGV-0386453_29 | PHROG | phrog_264 | major head protein | head and packaging |
| UHGV-0386453_29 | UniRef90 | UniRef90_UPI00164AAF0B | NA | NA |
| UHGV-0386453_29 | eggNOG-mapper | 742738.HMPREF9460_02515 | NA | NA |
| UHGV-0386453_29 | Pfam | PF09950 | NA | DUF2184 |
| UHGV-0386453_29 | COG | COG4834 | NA | NA |
| UHGV-0386453_29 | Structural annotation | PF09950, MF_04113, TIGR01554, COG4834 | NA | NA |
| UHGV-0386453_30 | PHROG | phrog_563 | virion structural protein | head and packaging |
| UHGV-0386453_30 | UniRef90 | UniRef90_UPI00164A2541 | head fiber protein | NA |
| UHGV-0386453_30 | eggNOG-mapper | 742738.HMPREF9460_02514 | NA | NA |
| UHGV-0386453_30 | Structural annotation | PF09956 | NA | NA |
| UHGV-0386453_31 | KOfam | K09960 | NA | NA |
| UHGV-0386453_31 | PHROG | phrog_16985 | NA | unknown function |
| UHGV-0386453_31 | UniRef90 | UniRef90_UPI00164BF670 | NA | NA |
| UHGV-0386453_31 | eggNOG-mapper | 742738.HMPREF9460_02512 | NA | NA |
| UHGV-0386453_31 | Pfam | PF09979 | NA | DUF2213 |
| UHGV-0386453_31 | COG | COG3566 | NA | NA |
| UHGV-0386453_31 | Structural annotation | PF09979, TIGR01543, COG3566 | NA | NA |
| UHGV-0386453_32 | PHROG | phrog_29883 | NA | unknown function |
| UHGV-0386453_33 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-0386453_33 | UniRef90 | UniRef90_UPI001958AD70 | minor capsid protein | NA |
| UHGV-0386453_33 | eggNOG-mapper | 742738.HMPREF9460_02508 | Portal protein | NA |
| UHGV-0386453_33 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-0386453_33 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-0386453_33 | Structural annotation | PF06152 | NA | NA |
| UHGV-0386453_34 | KOfam | K09961 | NA | NA |
| UHGV-0386453_34 | PHROG | phrog_146 | portal protein | head and packaging |
| UHGV-0386453_34 | UniRef90 | UniRef90_U2DFW0 | Phage-associated protein, HI1409 family | NA |
| UHGV-0386453_34 | eggNOG-mapper | 1007096.BAGW01000022_gene2656 | TIGRFAM phage-associated protein, HI1409 family | NA |
| UHGV-0386453_34 | Pfam | PF06381 | Anti-CBASS protein Acb1-like | Abc1-like |
| UHGV-0386453_34 | NCBIFam | TIGR01555.1 | phage-associated protein, HI1409 family | NA |
| UHGV-0386453_34 | COG | COG3567 | NA | NA |
| UHGV-0386453_34 | Structural annotation | PF06381, MF_04135, TIGR01555, COG3567 | NA | NA |
| UHGV-0386453_35 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0386453_35 | PHROG | phrog_10250 | NA | unknown function |
| UHGV-0386453_35 | UniRef90 | UniRef90_A0A096DBF3 | PBSX family phage terminase, large subunit | NA |
| UHGV-0386453_35 | eggNOG-mapper | 742738.HMPREF9460_02505 | Terminase-like family | NA |
| UHGV-0386453_35 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-0386453_35 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-0386453_35 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0386453_35 | Structural annotation | PF04466, PF17289, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0386453_36 | PHROG | phrog_2412 | NA | unknown function |
| UHGV-0386453_36 | eggNOG-mapper | 742738.HMPREF9460_02504 | NA | NA |
| UHGV-0386453_37 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0386453_37 | UniRef90 | UniRef90_UPI001C10AB33 | NA | NA |
| UHGV-0386453_37 | eggNOG-mapper | 580331.Thit_1400 | NA | NA |
| UHGV-0386453_37 | Structural annotation | PF07374, TIGR01636 | NA | NA |
| UHGV-0386453_45 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0386453_45 | UniRef90 | UniRef90_UPI0018774E0E | reductase | NA |
| UHGV-0386453_45 | eggNOG-mapper | 1235835.C814_01169 | NA | NA |
| UHGV-0386453_45 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0386453_45 | Structural annotation | PF01507, MF_01161, NF006327, COG0482 | NA | NA |
| UHGV-0386453_46 | dbAPIS | APIS008 | Alphafold2 predicted that Gad2 is an enzyme with a nucleotidyltransferase protein domain, suggesting that it inhibits Gabija via a mechanism of action different than Gad1. | NA |
| UHGV-0386453_47 | PHROG | phrog_757 | DNA methyltransferase | other |
| UHGV-0386453_47 | UniRef90 | UniRef90_A0A372V4B7 | DNA cytosine methyltransferase | NA |
| UHGV-0386453_47 | eggNOG-mapper | 485918.Cpin_3834 | DNA (cytosine-5-)-methyltransferase activity | NA |
| UHGV-0386453_47 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0386453_48 | PHROG | phrog_30550 | NA | unknown function |
| UHGV-0386453_48 | UniRef90 | UniRef90_A0A1Q6KLI0 | Hydrolase_2 domain-containing protein | NA |
| UHGV-0386453_48 | eggNOG-mapper | 1519439.JPJG01000077_gene920 | Cell Wall Hydrolase | NA |
| UHGV-0386453_48 | Structural annotation | COG3773 | NA | NA |
| UHGV-0386453_49 | PHROG | phrog_9804 | NA | unknown function |
| UHGV-0386453_49 | UniRef90 | UniRef90_R6LQQ5 | Inhibitor_G39P domain-containing protein | NA |
| UHGV-0386453_49 | eggNOG-mapper | 1410650.JHWL01000003_gene2847 | Loader and inhibitor of phage G40P | NA |
| UHGV-0386453_49 | Pfam | PF11417 | Loader and inhibitor of phage G40P | Inhibitor_G39P |
| UHGV-0386453_49 | Structural annotation | PF11417 | NA | NA |
| UHGV-0386453_50 | PHROG | phrog_16304 | NA | unknown function |
| UHGV-0386453_50 | UniRef90 | UniRef90_A0A810QMI2 | NA | NA |
| UHGV-0386453_50 | eggNOG-mapper | 445972.ANACOL_03338 | DnaD domain protein | NA |
| UHGV-0386453_50 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-0386453_50 | Pfam | PF07261 | Replication initiation and membrane attachment | DnaB_2 |
| UHGV-0386453_50 | NCBIFam | TIGR01446.1 | DnaD domain protein | NA |
| UHGV-0386453_50 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-0386453_50 | Structural annotation | PF19808, PF07261, TIGR01446, COG3935 | NA | NA |
| UHGV-0386453_51 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0386453_51 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0386453_51 | UniRef90 | UniRef90_R6IDK3 | Single-stranded DNA-binding protein | NA |
| UHGV-0386453_51 | eggNOG-mapper | 693746.OBV_19910 | Single-strand binding protein family | NA |
| UHGV-0386453_51 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0386453_51 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0386453_51 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0386453_51 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0386453_51 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0386453_52 | PHROG | phrog_7566 | NA | unknown function |
| UHGV-0386453_52 | eggNOG-mapper | 508419.F8J187_9CAUD | NA | NA |
| UHGV-0386453_53 | PHROG | phrog_1227 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0386453_53 | UniRef90 | UniRef90_A0A1Y3RPZ6 | NA | NA |
| UHGV-0386453_53 | eggNOG-mapper | 1567013.A0A0A7RVR3_9CAUD | NA | NA |
| UHGV-0386453_53 | Pfam | PF12684 | NA | DUF3799 |
| UHGV-0386453_53 | Structural annotation | PF12684, TIGR01896, COG4343 | NA | NA |
| UHGV-0386453_54 | PHROG | phrog_3657 | NA | unknown function |
| UHGV-0386453_54 | eggNOG-mapper | 1071073.KI530540_gene3354 | NA | NA |
| UHGV-0386453_58 | eggNOG-mapper | 1235835.C814_03153 | NA | NA |
| UHGV-0386453_58 | Structural annotation | PF12728, TIGR01764, COG3311 | NA | NA |
| UHGV-0386453_61 | UniRef90 | UniRef90_A0A396Q7L7 | XRE family transcriptional regulator | NA |
| UHGV-0386453_61 | eggNOG-mapper | 1132442.KB889752_gene869 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0386453_61 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0386453_61 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0386453_62 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-0386453_62 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0386453_62 | UniRef90 | UniRef90_UPI0013DDB973 | XRE family transcriptional regulator | NA |
| UHGV-0386453_62 | eggNOG-mapper | 879308.HMPREF9130_0437 | Represses a number of genes involved in the response to DNA damage (SOS response) | NA |
| UHGV-0386453_62 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0386453_62 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0386453_62 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-0386453_62 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0386453_62 | Structural annotation | PF00717, PF01381, MF_00015, TIGR00498, COG1974 | NA | NA |
| UHGV-0386453_63 | UniRef90 | UniRef90_A0A3R6Q1U3 | NINE protein | NA |
| UHGV-0386453_63 | eggNOG-mapper | 742740.HMPREF9474_03106 | TM2 domain | NA |
| UHGV-0386453_63 | COG | COG2314 | NA | NA |
| UHGV-0386453_64 | KOfam | K14059 | int; integrase | NA |
| UHGV-0386453_64 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0386453_64 | UniRef90 | UniRef90_UPI001874116E | tyrosine-type recombinase/integrase | NA |
| UHGV-0386453_64 | eggNOG-mapper | 1235835.C814_03141 | Belongs to the 'phage' integrase family | NA |
| UHGV-0386453_64 | Pfam | PF14657 | Arm DNA-binding domain | Arm-DNA-bind_4 |
| UHGV-0386453_64 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0386453_64 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0386453_64 | Structural annotation | PF00589, MF_01808, TIGR02224, COG4974 | NA | NA |