| UHGV-1337943_1 | PHROG | phrog_199 | holin | lysis |
| UHGV-1337943_1 | UniRef90 | UniRef90_A0A414REB4 | Holin | NA |
| UHGV-1337943_1 | eggNOG-mapper | 428126.CLOSPI_02191 | Bacteriophage holin family | NA |
| UHGV-1337943_1 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-1337943_1 | NCBIFam | TIGR01593.1 | toxin secretion/phage lysis holin | NA |
| UHGV-1337943_1 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-1337943_2 | PHROG | phrog_17196 | kinase | other |
| UHGV-1337943_2 | UniRef90 | UniRef90_A0A3R6GQJ1 | Peptidase S74 domain-containing protein | NA |
| UHGV-1337943_2 | eggNOG-mapper | 483218.BACPEC_01141 | NA | NA |
| UHGV-1337943_2 | Pfam | PF13884 | Chaperone of endosialidase | Peptidase_S74 |
| UHGV-1337943_4 | PHROG | phrog_18190 | NA | unknown function |
| UHGV-1337943_4 | UniRef90 | UniRef90_C7GBZ4 | Peptidase S74 domain-containing protein | NA |
| UHGV-1337943_4 | eggNOG-mapper | 1235790.C805_00089 | NA | NA |
| UHGV-1337943_4 | Pfam | PF13884 | Chaperone of endosialidase | Peptidase_S74 |
| UHGV-1337943_4 | Structural annotation | PF05113, NF033848, COG3500 | NA | NA |
| UHGV-1337943_5 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-1337943_5 | eggNOG-mapper | 1235790.C805_00088 | NA | NA |
| UHGV-1337943_5 | Pfam | PF20458 | NA | DUF6711 |
| UHGV-1337943_5 | Structural annotation | PF20458, TIGR01633, COG3499 | NA | NA |
| UHGV-1337943_6 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-1337943_6 | UniRef90 | UniRef90_A0A1H7MQ92 | Phage-related protein | NA |
| UHGV-1337943_6 | eggNOG-mapper | 411902.CLOBOL_00126 | NA | NA |
| UHGV-1337943_6 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1337943_7 | PHROG | phrog_706 | NA | unknown function |
| UHGV-1337943_7 | UniRef90 | UniRef90_C7GBZ7 | Bacteriophage Gp15 protein | NA |
| UHGV-1337943_7 | eggNOG-mapper | 1235790.C805_00084 | Bacteriophage Gp15 protein | NA |
| UHGV-1337943_7 | Pfam | PF06854 | Bacteriophage Gp15 protein | Phage_Gp15 |
| UHGV-1337943_7 | Structural annotation | PF06854 | NA | NA |
| UHGV-1337943_8 | UniRef90 | UniRef90_A0A412KF72 | RNA polymerase subunit sigma | NA |
| UHGV-1337943_9 | PHROG | phrog_3099 | NA | unknown function |
| UHGV-1337943_9 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-1337943_10 | PHROG | phrog_3266 | tail completion | connector |
| UHGV-1337943_10 | eggNOG-mapper | 397290.C810_05232 | NA | NA |
| UHGV-1337943_10 | Structural annotation | PF12691 | NA | NA |
| UHGV-1337943_11 | PHROG | phrog_3366 | NA | unknown function |
| UHGV-1337943_11 | eggNOG-mapper | 476272.RUMHYD_01779 | NA | NA |
| UHGV-1337943_11 | Structural annotation | PF20536, COG5614 | NA | NA |
| UHGV-1337943_12 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-1337943_12 | UniRef90 | UniRef90_UPI00189A7662 | NA | NA |
| UHGV-1337943_12 | eggNOG-mapper | 588581.Cpap_1521 | NA | NA |
| UHGV-1337943_12 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-1337943_12 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-1337943_12 | Structural annotation | PF11195 | NA | NA |
| UHGV-1337943_13 | PHROG | phrog_541 | head-tail adaptor | connector |
| UHGV-1337943_13 | UniRef90 | UniRef90_A0A371AQT0 | NA | NA |
| UHGV-1337943_13 | eggNOG-mapper | 476272.RUMHYD_01778 | NA | NA |
| UHGV-1337943_14 | PHROG | phrog_247 | major head protein | head and packaging |
| UHGV-1337943_14 | UniRef90 | UniRef90_A0A3R6GNQ1 | Phage coat protein | NA |
| UHGV-1337943_14 | eggNOG-mapper | 536233.CLO_0886 | NA | NA |
| UHGV-1337943_14 | Pfam | PF20036 | Major capsid protein 13-like | Gp13-like |
| UHGV-1337943_14 | COG | COG1106 | ATPase/GTPase, AAA15 family | NA |
| UHGV-1337943_14 | Structural annotation | PF20036, MF_04113, TIGR04387, COG4653 | NA | NA |
| UHGV-1337943_15 | eggNOG-mapper | 1539298.JO41_08210 | Phage minor structural protein GP20 | NA |
| UHGV-1337943_18 | PHROG | phrog_4608 | anti-repressor | transcription regulation |
| UHGV-1337943_18 | UniRef90 | UniRef90_A0A413YTH5 | ORF6N domain-containing protein | NA |
| UHGV-1337943_18 | eggNOG-mapper | 1408823.AXUS01000024_gene2689 | ORF6C domain | NA |
| UHGV-1337943_18 | Pfam | PF10543 | ORF6N domain | ORF6N |
| UHGV-1337943_18 | COG | COG3646 | Phage regulatory protein Rha | NA |
| UHGV-1337943_19 | Structural annotation | PF07878, NF010256, COG4691 | NA | NA |
| UHGV-1337943_20 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-1337943_20 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1337943_20 | UniRef90 | UniRef90_A0A413YTG4 | XRE family transcriptional regulator | NA |
| UHGV-1337943_20 | eggNOG-mapper | 857293.CAAU_0976 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-1337943_20 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1337943_20 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1337943_20 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-1337943_21 | UniRef90 | UniRef90_R6BU26 | Peptidyl-dipeptidase Dcp | NA |
| UHGV-1337943_22 | UniRef90 | UniRef90_A0A413YTH6 | ACB domain-containing protein | NA |
| UHGV-1337943_23 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-1337943_23 | UniRef90 | UniRef90_A0A6L5YIK0 | Phage capsid protein | NA |
| UHGV-1337943_23 | eggNOG-mapper | 663278.Ethha_0091 | NA | NA |
| UHGV-1337943_23 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-1337943_23 | COG | COG2369 | NA | NA |
| UHGV-1337943_23 | Structural annotation | PF06152, PF04002 | NA | NA |
| UHGV-1337943_24 | PHROG | phrog_556 | minor head protein | head and packaging |
| UHGV-1337943_24 | UniRef90 | UniRef90_UPI000E4A8F9F | minor capsid protein | NA |
| UHGV-1337943_24 | eggNOG-mapper | 476272.RUMHYD_01780 | NA | NA |
| UHGV-1337943_24 | Pfam | PF11114 | Minor capsid protein | Minor_capsid_2 |
| UHGV-1337943_24 | Structural annotation | PF11114 | NA | NA |
| UHGV-1337943_25 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-1337943_25 | UniRef90 | UniRef90_A0A3B9CD47 | Phage capsid protein | NA |
| UHGV-1337943_25 | eggNOG-mapper | 476272.RUMHYD_01758 | phage minor capsid protein | NA |
| UHGV-1337943_25 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-1337943_26 | PHROG | phrog_1233 | NA | unknown function |
| UHGV-1337943_26 | UniRef90 | UniRef90_UPI001C39EFB9 | Dienelactone hydrolase family protein | NA |
| UHGV-1337943_26 | eggNOG-mapper | 357809.Cphy_2967 | NA | NA |
| UHGV-1337943_27 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-1337943_27 | PHROG | phrog_5653 | terminase large subunit | head and packaging |
| UHGV-1337943_27 | UniRef90 | UniRef90_A0A3R6H2I4 | Terminase_3 domain-containing protein | NA |
| UHGV-1337943_27 | eggNOG-mapper | 33035.JPJF01000106_gene3136 | Terminase small subunit | NA |
| UHGV-1337943_27 | Pfam | PF10668 | Phage terminase small subunit | Phage_terminase |
| UHGV-1337943_27 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-1337943_27 | Pfam | PF04466 | Phage terminase large subunit | Terminase_3 |
| UHGV-1337943_27 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-1337943_27 | Structural annotation | PF04466, PF17288, PF06056, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1337943_28 | PHROG | phrog_9479 | NA | unknown function |
| UHGV-1337943_28 | Structural annotation | PF15529 | NA | NA |
| UHGV-1337943_29 | PHROG | phrog_8680 | NA | unknown function |
| UHGV-1337943_29 | UniRef90 | UniRef90_A0A3R6K733 | NA | NA |
| UHGV-1337943_29 | eggNOG-mapper | 411470.RUMGNA_02208 | NA | NA |
| UHGV-1337943_29 | Pfam | PF14386 | NA | DUF4417 |
| UHGV-1337943_29 | Structural annotation | PF14386 | NA | NA |
| UHGV-1337943_30 | UniRef90 | UniRef90_UPI001C0249A7 | ABC transporter ATP-binding protein | NA |
| UHGV-1337943_31 | UniRef90 | UniRef90_UPI001C02B1D3 | NA | NA |
| UHGV-1337943_31 | Pfam | PF20037 | NA | DUF6440 |
| UHGV-1337943_31 | Structural annotation | PF20037 | NA | NA |
| UHGV-1337943_33 | eggNOG-mapper | 760568.Desku_0913 | NA | NA |
| UHGV-1337943_34 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1337943_34 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-1337943_34 | UniRef90 | UniRef90_A0A3R6F6T5 | Methyltransferase | NA |
| UHGV-1337943_34 | eggNOG-mapper | 658655.HMPREF0988_00878 | DNA methylase | NA |
| UHGV-1337943_34 | PADLOC | MTase_II_00157 | Type II methyltransferase | RM |
| UHGV-1337943_34 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1337943_34 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1337943_34 | Structural annotation | PF01555, MF_01872, NF010253, COG0863 | NA | NA |
| UHGV-1337943_35 | eggNOG-mapper | 693746.OBV_43240 | NA | NA |
| UHGV-1337943_35 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1337943_36 | UniRef90 | UniRef90_A0A2H4JC51 | Putative 3'-phosphoadenosine 5'-phosphosulfatesulfotransferase/FAD synthetase-related enzyme | NA |
| UHGV-1337943_36 | eggNOG-mapper | 693746.OBV_43240 | NA | NA |
| UHGV-1337943_36 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1337943_38 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1337943_38 | UniRef90 | UniRef90_R5I2H7 | HNH endonuclease family prophage LambdaSa2 | NA |
| UHGV-1337943_38 | eggNOG-mapper | 537874.B3GVX7_9CAUD | HNH endonuclease | NA |
| UHGV-1337943_38 | PADLOC | HEase_00016 | homing endonuclease | RM |
| UHGV-1337943_38 | Pfam | PF07463 | NUMOD4 motif | NUMOD4 |
| UHGV-1337943_38 | Structural annotation | PF07453, TIGR01453 | NA | NA |
| UHGV-1337943_39 | PHROG | phrog_874 | NA | unknown function |
| UHGV-1337943_39 | UniRef90 | UniRef90_A0A6N7W7Q7 | ASCH domain-containing protein | NA |
| UHGV-1337943_39 | eggNOG-mapper | 411468.CLOSCI_00298 | NA | NA |
| UHGV-1337943_39 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-1337943_41 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-1337943_41 | UniRef90 | UniRef90_A0A412RQU3 | YopX domain-containing protein | NA |
| UHGV-1337943_41 | eggNOG-mapper | 411470.RUMGNA_02199 | NA | NA |
| UHGV-1337943_41 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-1337943_42 | UniRef90 | UniRef90_A0A415TX35 | BAH domain-containing protein | NA |
| UHGV-1337943_42 | eggNOG-mapper | 397290.C810_01492 | NA | NA |
| UHGV-1337943_43 | UniRef90 | UniRef90_UPI0011110A17 | NA | NA |
| UHGV-1337943_43 | eggNOG-mapper | 665950.HMPREF1025_02540 | NA | NA |
| UHGV-1337943_44 | PHROG | phrog_15198 | NA | unknown function |
| UHGV-1337943_44 | UniRef90 | UniRef90_A0A6L6XDH6 | NA | NA |
| UHGV-1337943_44 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1337943_45 | PHROG | phrog_21026 | NA | unknown function |
| UHGV-1337943_46 | PHROG | phrog_37044 | NA | unknown function |
| UHGV-1337943_46 | eggNOG-mapper | 397290.C810_00402 | NA | NA |
| UHGV-1337943_47 | PHROG | phrog_16304 | NA | unknown function |
| UHGV-1337943_47 | UniRef90 | UniRef90_A0A3R6H2J6 | NA | NA |
| UHGV-1337943_47 | eggNOG-mapper | 411490.ANACAC_00800 | NA | NA |
| UHGV-1337943_47 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-1337943_47 | Structural annotation | PF19808 | NA | NA |
| UHGV-1337943_48 | KOfam | K01160 | rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10] | NA |
| UHGV-1337943_48 | PHROG | phrog_1682 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1337943_48 | UniRef90 | UniRef90_A0A415TWS7 | RusA family crossover junction endodeoxyribonuclease | NA |
| UHGV-1337943_48 | eggNOG-mapper | 910314.HMPREF9220_1104 | Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC | NA |
| UHGV-1337943_48 | COG | COG4570 | Holliday junction resolvase RusA (prophage-encoded endonuclease) | NA |
| UHGV-1337943_48 | Structural annotation | PF19595, NF007305, COG4570 | NA | NA |
| UHGV-1337943_49 | PHROG | phrog_463 | anti-repressor | transcription regulation |
| UHGV-1337943_49 | UniRef90 | UniRef90_A0A6N3H967 | Bro-N domain-containing protein | NA |
| UHGV-1337943_49 | eggNOG-mapper | 411490.ANACAC_00813 | BRO family, N-terminal domain | NA |
| UHGV-1337943_49 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-1337943_49 | Pfam | PF10552 | ORF6C domain | ORF6C |
| UHGV-1337943_49 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-1337943_49 | Structural annotation | PF10552, PF02498, TIGR02681, COG3617 | NA | NA |
| UHGV-1337943_50 | PHROG | phrog_7566 | NA | unknown function |
| UHGV-1337943_50 | UniRef90 | UniRef90_UPI001C0181E7 | phosphoenolpyruvate carboxykinase | NA |
| UHGV-1337943_51 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-1337943_51 | UniRef90 | UniRef90_A0A285PU94 | Recombinase NinB | NA |
| UHGV-1337943_51 | eggNOG-mapper | 1410650.JHWL01000003_gene2850 | NA | NA |
| UHGV-1337943_51 | Structural annotation | PF05772, NF007281 | NA | NA |
| UHGV-1337943_52 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1337943_52 | UniRef90 | UniRef90_UPI001C031D02 | ERF family protein | NA |
| UHGV-1337943_52 | eggNOG-mapper | 357809.Cphy_2988 | ERF superfamily | NA |
| UHGV-1337943_52 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-1337943_52 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-1337943_52 | Structural annotation | PF04404, TIGR00607, COG4712 | NA | NA |
| UHGV-1337943_53 | PHROG | phrog_4400 | NA | unknown function |
| UHGV-1337943_53 | eggNOG-mapper | 886882.PPSC2_p0514 | NA | NA |
| UHGV-1337943_53 | dbAPIS | APIS008 | Alphafold2 predicted that Gad2 is an enzyme with a nucleotidyltransferase protein domain, suggesting that it inhibits Gabija via a mechanism of action different than Gad1. | NA |
| UHGV-1337943_53 | Structural annotation | PF01743, MF_00957, TIGR01942, COG0617 | NA | NA |
| UHGV-1337943_54 | PHROG | phrog_674 | NA | unknown function |
| UHGV-1337943_54 | UniRef90 | UniRef90_UPI001C01FE50 | NA | NA |
| UHGV-1337943_54 | eggNOG-mapper | 411460.RUMTOR_02065 | NA | NA |
| UHGV-1337943_54 | Pfam | PF07083 | NA | DUF1351 |
| UHGV-1337943_54 | Structural annotation | PF07083 | NA | NA |
| UHGV-1337943_55 | Structural annotation | PF21596, TIGR03081 | NA | NA |
| UHGV-1337943_57 | UniRef90 | UniRef90_A0A414RMV5 | Lectin-1 | NA |
| UHGV-1337943_57 | Structural annotation | COG3296 | NA | NA |
| UHGV-1337943_58 | UniRef90 | UniRef90_A0A414RMU8 | XRE family transcriptional regulator | NA |
| UHGV-1337943_58 | Structural annotation | PF21291, MF_00535, NF041951, COG1513 | NA | NA |
| UHGV-1337943_59 | PHROG | phrog_4621 | NA | unknown function |
| UHGV-1337943_59 | eggNOG-mapper | 1415774.U728_1710 | NA | NA |
| UHGV-1337943_62 | PHROG | phrog_9976 | anti-repressor | transcription regulation |
| UHGV-1337943_62 | UniRef90 | UniRef90_R6UYN4 | Bro-N domain-containing protein | NA |
| UHGV-1337943_62 | eggNOG-mapper | 1449050.JNLE01000005_gene3959 | BRO family, N-terminal domain | NA |
| UHGV-1337943_62 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-1337943_62 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-1337943_62 | Structural annotation | PF02498, NF008573, COG3617 | NA | NA |