| UHGV-1350280_1 | KOfam | K04763 | xerD; integrase/recombinase XerD | NA |
| UHGV-1350280_1 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1350280_1 | UniRef90 | UniRef90_A0A1Q6G280 | Recombinase | NA |
| UHGV-1350280_1 | eggNOG-mapper | 1121100.JCM6294_508 | Phage integrase SAM-like domain | NA |
| UHGV-1350280_1 | Pfam | PF17293 | Arm DNA-binding domain | Arm-DNA-bind_5 |
| UHGV-1350280_1 | Pfam | PF13102 | Phage integrase SAM-like domain | Phage_int_SAM_5 |
| UHGV-1350280_1 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1350280_1 | Structural annotation | PF17293, PF13102, PF00589, MF_01808, NF007246, COG4974 | NA | NA |
| UHGV-1350280_2 | Structural annotation | PF14282 | NA | NA |
| UHGV-1350280_3 | UniRef90 | UniRef90_UPI0007FB56D6 | NA | NA |
| UHGV-1350280_3 | eggNOG-mapper | 411476.BACOVA_03957 | NA | NA |
| UHGV-1350280_3 | Pfam | PF16476 | NA | DUF5053 |
| UHGV-1350280_3 | Structural annotation | PF16476 | NA | NA |
| UHGV-1350280_4 | KOfam | K02342 | dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] | NA |
| UHGV-1350280_4 | PHROG | phrog_192 | DNA polymerase exonuclease subunit | DNA, RNA and nucleotide metabolism |
| UHGV-1350280_4 | UniRef90 | UniRef90_A0A318N7M5 | BRCT domain-containing protein | NA |
| UHGV-1350280_4 | eggNOG-mapper | 888832.HMPREF9420_0938 | breast cancer carboxy-terminal domain | NA |
| UHGV-1350280_4 | PADLOC | cd06127 | CAS-I,CAS-II,CAS-III,CAS-IV,CAS-V,CAS-VI; associated | CRISPR-CAS |
| UHGV-1350280_4 | Pfam | PF00929 | Exonuclease | RNase_T |
| UHGV-1350280_4 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-1350280_4 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1350280_4 | Structural annotation | PF00929, PF00533, MF_00157, NF005289, COG0847 | NA | NA |
| UHGV-1350280_5 | eggNOG-mapper | 929703.KE386491_gene1312 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-1350280_5 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1350280_6 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-1350280_6 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-1350280_6 | UniRef90 | UniRef90_UPI0008D95E33 | LexA family transcriptional regulator | NA |
| UHGV-1350280_6 | eggNOG-mapper | 563031.HMPREF0666_01107 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-1350280_6 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-1350280_6 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-1350280_6 | Structural annotation | PF00717, PF12844, MF_00015, TIGR00498, COG2932 | NA | NA |
| UHGV-1350280_8 | UniRef90 | UniRef90_A0A6I0S4I3 | DNA-binding protein | NA |
| UHGV-1350280_8 | eggNOG-mapper | 1121100.JCM6294_512 | NA | NA |
| UHGV-1350280_8 | Structural annotation | PF12728, TIGR01764, COG3311 | NA | NA |
| UHGV-1350280_10 | PHROG | phrog_2562 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-1350280_10 | UniRef90 | UniRef90_UPI001D083AE2 | NA | NA |
| UHGV-1350280_10 | eggNOG-mapper | 326298.Suden_1630 | NA | NA |
| UHGV-1350280_10 | Pfam | PF14297 | Lin1244/Lin1753-like, N-terminal | Lin1244_N |
| UHGV-1350280_10 | Structural annotation | PF14297 | NA | NA |
| UHGV-1350280_11 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-1350280_11 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1350280_11 | UniRef90 | UniRef90_A0A413ITT5 | Replicative DNA helicase | NA |
| UHGV-1350280_11 | eggNOG-mapper | 1077285.AGDG01000022_gene1141 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-1350280_11 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-1350280_11 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-1350280_11 | NCBIFam | TIGR00665.1 | replicative DNA helicase | NA |
| UHGV-1350280_11 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-1350280_11 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-1350280_13 | Structural annotation | PF04703, MF_01819 | NA | NA |
| UHGV-1350280_15 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1350280_15 | PHROG | phrog_363 | DNA methyltransferase | other |
| UHGV-1350280_15 | UniRef90 | UniRef90_UPI000D0AC0A7 | DNA cytosine methyltransferase | NA |
| UHGV-1350280_15 | eggNOG-mapper | 1347393.HG726022_gene3592 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1350280_15 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-1350280_15 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1350280_15 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1350280_15 | Structural annotation | PF00145, MF_00351, TIGR00675, COG0270 | NA | NA |
| UHGV-1350280_16 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1350280_16 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1350280_16 | UniRef90 | UniRef90_UPI000D0BBDF7 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-1350280_16 | eggNOG-mapper | 742817.HMPREF9449_01776 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-1350280_16 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-1350280_16 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1350280_16 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1350280_16 | Structural annotation | PF01507, MF_00063, NF010369, COG0175 | NA | NA |
| UHGV-1350280_17 | UniRef90 | UniRef90_A0A413ITX0 | NA | NA |
| UHGV-1350280_17 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1350280_19 | PHROG | phrog_9236 | pyrophosphatase | other |
| UHGV-1350280_19 | eggNOG-mapper | 1235788.C802_00059 | NA | NA |
| UHGV-1350280_19 | Structural annotation | PF08761, COG4508 | NA | NA |
| UHGV-1350280_20 | PHROG | phrog_2776 | NA | unknown function |
| UHGV-1350280_20 | UniRef90 | UniRef90_UPI001297AEBA | MmcB family DNA repair protein | NA |
| UHGV-1350280_20 | eggNOG-mapper | 227470.Q76Z55_9CAUD | NA | NA |
| UHGV-1350280_20 | Structural annotation | PF06319, NF033832, COG5321 | NA | NA |
| UHGV-1350280_25 | KOfam | K04763 | xerD; integrase/recombinase XerD | NA |
| UHGV-1350280_25 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1350280_25 | UniRef90 | UniRef90_UPI000D0AF22A | tyrosine-type recombinase/integrase | NA |
| UHGV-1350280_25 | eggNOG-mapper | 926692.AZYG01000026_gene1759 | Belongs to the 'phage' integrase family | NA |
| UHGV-1350280_25 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1350280_25 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-1350280_25 | Structural annotation | PF00589, PF02899, MF_01807, NF001399, COG4974 | NA | NA |
| UHGV-1350280_27 | PHROG | phrog_83 | terminase small subunit | head and packaging |
| UHGV-1350280_27 | UniRef90 | UniRef90_A0A413IG44 | Phage terminase small subunit P27 family | NA |
| UHGV-1350280_27 | eggNOG-mapper | 1433126.BN938_0084 | Phage terminase, small subunit | NA |
| UHGV-1350280_27 | Pfam | PF05119 | Phage terminase, small subunit | Terminase_4 |
| UHGV-1350280_27 | NCBIFam | TIGR01558.1 | phage terminase small subunit P27 family | NA |
| UHGV-1350280_27 | COG | COG3747 | Phage terminase, small subunit | NA |
| UHGV-1350280_27 | Structural annotation | PF05119, TIGR01558, COG3747 | NA | NA |
| UHGV-1350280_28 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-1350280_28 | UniRef90 | UniRef90_UPI000D0B1E8B | terminase large subunit | NA |
| UHGV-1350280_28 | eggNOG-mapper | 2754.EH55_13175 | Terminase | NA |
| UHGV-1350280_28 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-1350280_28 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-1350280_28 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-1350280_28 | Structural annotation | PF20441, PF03354, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-1350280_29 | PHROG | phrog_518 | Rha-like transcriptional regulator | transcription regulation |
| UHGV-1350280_29 | UniRef90 | UniRef90_UPI0007FB4318 | Rha family transcriptional regulator | NA |
| UHGV-1350280_29 | eggNOG-mapper | 90371.CY43_10725 | Phage regulatory protein, Rha family | NA |
| UHGV-1350280_29 | Pfam | PF09669 | Phage regulatory protein Rha (Phage_pRha) | Phage_pRha |
| UHGV-1350280_29 | NCBIFam | TIGR02681.1 | phage regulatory protein, Rha family | NA |
| UHGV-1350280_29 | COG | COG3646 | Phage regulatory protein Rha | NA |
| UHGV-1350280_31 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-1350280_31 | PHROG | phrog_5817 | anti-repressor Ant | transcription regulation |
| UHGV-1350280_31 | UniRef90 | UniRef90_A0A0X8JB19 | AntA domain-containing protein | NA |
| UHGV-1350280_31 | eggNOG-mapper | 992406.RIA_2123 | AntA/AntB antirepressor | NA |
| UHGV-1350280_31 | Pfam | PF08346 | AntA/AntB antirepressor | AntA |
| UHGV-1350280_31 | COG | COG3561 | Phage anti-repressor protein Ant | NA |
| UHGV-1350280_31 | Structural annotation | PF08346, TIGR02681, COG3561 | NA | NA |
| UHGV-1350280_32 | UniRef90 | UniRef90_A0A849XHT2 | Type II toxin-antitoxin system HicB family antitoxin | NA |
| UHGV-1350280_32 | eggNOG-mapper | 1392486.JIAF01000004_gene1071 | PFAM Uncharacterised protein family UPF0150 | NA |
| UHGV-1350280_32 | COG | COG1598 | Antitoxin component HicB of the HicAB toxin-antitoxin system | NA |
| UHGV-1350280_32 | Structural annotation | PF21748, NF041951, COG1598 | NA | NA |
| UHGV-1350280_33 | KOfam | K07339 | hicA; mRNA interferase HicA [EC:3.1.-.-] | NA |
| UHGV-1350280_33 | PHROG | phrog_353 | toxin | moron, auxiliary metabolic gene and host takeover |
| UHGV-1350280_33 | UniRef90 | UniRef90_A0A831LKB7 | Type II toxin-antitoxin system HicA family toxin | NA |
| UHGV-1350280_33 | eggNOG-mapper | 1392486.JIAF01000004_gene1070 | HicA toxin of bacterial toxin-antitoxin, | NA |
| UHGV-1350280_33 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-1350280_33 | Structural annotation | PF07927, COG1724 | NA | NA |
| UHGV-1350280_34 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-1350280_34 | UniRef90 | UniRef90_A0A413IG58 | Phage portal protein | NA |
| UHGV-1350280_34 | eggNOG-mapper | 1414720.CBYM010000005_gene1370 | Phage portal protein, HK97 family | NA |
| UHGV-1350280_34 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-1350280_34 | NCBIFam | TIGR01537.1 | phage portal protein | NA |
| UHGV-1350280_34 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-1350280_34 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-1350280_35 | KOfam | K06904 | NA | NA |
| UHGV-1350280_35 | PHROG | phrog_617 | major head protein | head and packaging |
| UHGV-1350280_35 | UniRef90 | UniRef90_UPI000D0B9511 | HK97 family phage prohead protease | NA |
| UHGV-1350280_35 | eggNOG-mapper | 553175.POREN0001_0011 | Phage prohead protease, HK97 family | NA |
| UHGV-1350280_35 | Pfam | PF04586 | Caudovirus prohead serine protease | Peptidase_S78 |
| UHGV-1350280_35 | COG | COG3740 | Phage head maturation protease | NA |
| UHGV-1350280_36 | PHROG | phrog_617 | major head protein | head and packaging |
| UHGV-1350280_36 | UniRef90 | UniRef90_UPI000D0BD3A0 | phage major capsid protein | NA |
| UHGV-1350280_36 | eggNOG-mapper | 547045.NEISICOT_01400 | Phage capsid family | NA |
| UHGV-1350280_36 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-1350280_36 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-1350280_36 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-1350280_36 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1350280_37 | UniRef90 | UniRef90_A0A413IG96 | Helix-hairpin-helix domain-containing protein | NA |
| UHGV-1350280_37 | Pfam | PF14520 | Helix-hairpin-helix domain | HHH_5 |
| UHGV-1350280_37 | Structural annotation | PF01281, PF14520 | NA | NA |
| UHGV-1350280_38 | PHROG | phrog_442 | head-tail adaptor | connector |
| UHGV-1350280_38 | UniRef90 | UniRef90_UPI000D0B385D | phage gp6-like head-tail connector protein | NA |
| UHGV-1350280_38 | eggNOG-mapper | 1231190.NA8A_19835 | Phage gp6-like head-tail connector protein | NA |
| UHGV-1350280_38 | Pfam | PF05135 | Phage gp6-like head-tail connector protein | Phage_connect_1 |
| UHGV-1350280_38 | NCBIFam | TIGR02215.1 | phage conserved hypothetical protein, phiE125 gp8 family | NA |
| UHGV-1350280_38 | Structural annotation | PF05135, TIGR02215 | NA | NA |
| UHGV-1350280_39 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-1350280_43 | PHROG | phrog_1407 | major tail protein | tail |
| UHGV-1350280_43 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-1350280_44 | Structural annotation | PF19591 | NA | NA |
| UHGV-1350280_46 | PHROG | phrog_37298 | NA | unknown function |
| UHGV-1350280_46 | UniRef90 | UniRef90_A0A413IG66 | Phage tail length tape measure family protein | NA |
| UHGV-1350280_46 | eggNOG-mapper | 1121101.HMPREF1532_02608 | domain protein | NA |
| UHGV-1350280_46 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-1350280_46 | COG | COG5280 | Phage-related minor tail protein | NA |
| UHGV-1350280_47 | PHROG | phrog_38044 | NA | unknown function |
| UHGV-1350280_47 | eggNOG-mapper | 762968.HMPREF9441_00566 | cellulase activity | NA |
| UHGV-1350280_47 | COG | COG4733 | Phage-related protein, tail protein J | NA |
| UHGV-1350280_50 | UniRef90 | UniRef90_UPI0011226A1F | phage holin family protein | NA |
| UHGV-1350280_50 | eggNOG-mapper | 1347393.HG726026_gene2534 | NA | NA |
| UHGV-1350280_50 | Structural annotation | PF05105, COG4824 | NA | NA |
| UHGV-1350280_51 | KOfam | K08640 | E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] | NA |
| UHGV-1350280_51 | PHROG | phrog_894 | endolysin | lysis |
| UHGV-1350280_51 | UniRef90 | UniRef90_UPI0007FB42E2 | D-Ala-D-Ala carboxypeptidase family metallohydrolase | NA |
| UHGV-1350280_51 | eggNOG-mapper | 563192.HMPREF0179_05268 | Peptidase M15 | NA |
| UHGV-1350280_51 | Pfam | PF08291 | Peptidase M15 | Peptidase_M15_3 |
| UHGV-1350280_51 | COG | COG3108 | NA | NA |
| UHGV-1350280_51 | Structural annotation | PF08291, NF007557, COG3108 | NA | NA |