| UHGV-1356435_1 | PHROG | phrog_422 | major head protein | head and packaging |
| UHGV-1356435_1 | UniRef90 | UniRef90_A0A3C2DU69 | Capsid protein | NA |
| UHGV-1356435_1 | eggNOG-mapper | 1235790.C805_00073 | NA | NA |
| UHGV-1356435_1 | Structural annotation | PF19821, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-1356435_2 | PHROG | phrog_31690 | NA | unknown function |
| UHGV-1356435_2 | Structural annotation | PF18207 | NA | NA |
| UHGV-1356435_3 | Pfam | PF05135 | Phage gp6-like head-tail connector protein | Phage_connect_1 |
| UHGV-1356435_4 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-1356435_5 | eggNOG-mapper | 1285586.H131_11763 | Bacteriophage HK97-gp10, putative tail-component | NA |
| UHGV-1356435_5 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-1356435_5 | Structural annotation | PF20039, TIGR01725, COG5005 | NA | NA |
| UHGV-1356435_6 | Structural annotation | PF09646 | NA | NA |
| UHGV-1356435_7 | Structural annotation | PF16463, TIGR02241, COG5437 | NA | NA |
| UHGV-1356435_8 | Structural annotation | PF19591, TIGR01674 | NA | NA |
| UHGV-1356435_10 | COG | COG5280 | Phage-related minor tail protein | NA |
| UHGV-1356435_11 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-1356435_11 | eggNOG-mapper | 665956.HMPREF1032_03629 | NA | NA |
| UHGV-1356435_11 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-1356435_12 | PHROG | phrog_13879 | NA | unknown function |
| UHGV-1356435_12 | eggNOG-mapper | 1120746.CCNL01000014_gene2107 | NA | NA |
| UHGV-1356435_13 | UniRef90 | UniRef90_UPI00114428A3 | InlB B-repeat-containing protein | NA |
| UHGV-1356435_13 | eggNOG-mapper | 97138.C820_00171 | COG COG3291 FOG PKD repeat | NA |
| UHGV-1356435_13 | Pfam | PF18998 | Divergent InlB B-repeat domain | Flg_new_2 |
| UHGV-1356435_13 | COG | COG3209 | NA | NA |
| UHGV-1356435_20 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-1356435_20 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_20 | UniRef90 | UniRef90_A0A3B9Z822 | Helicase ATP-binding domain-containing protein | NA |
| UHGV-1356435_20 | eggNOG-mapper | 1416012.V5US64_9CAUD | helicase activity | NA |
| UHGV-1356435_20 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-1356435_20 | Structural annotation | PF00176, PF00271, MF_01821, NF041790, COG0553 | NA | NA |
| UHGV-1356435_22 | KOfam | K18951 | gp30; DNA ligase [EC:6.5.1.1] | NA |
| UHGV-1356435_22 | PHROG | phrog_114 | ATP-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_22 | UniRef90 | UniRef90_UPI000F637511 | ATP-dependent DNA ligase | NA |
| UHGV-1356435_22 | eggNOG-mapper | 1308863.U5JA36_9CAUD | DNA ligase (ATP) activity | NA |
| UHGV-1356435_22 | Pfam | PF01068 | ATP dependent DNA ligase domain | DNA_ligase_A_M |
| UHGV-1356435_22 | Pfam | PF14743 | DNA ligase OB-like domain | DNA_ligase_OB_2 |
| UHGV-1356435_22 | Structural annotation | PF01068, PF17879, MF_00407, NF002868, COG1793 | NA | NA |
| UHGV-1356435_26 | eggNOG-mapper | 470145.BACCOP_03749 | NA | NA |
| UHGV-1356435_26 | COG | COG3613 | Nucleoside 2-deoxyribosyltransferase | NA |
| UHGV-1356435_30 | PHROG | phrog_7839 | NA | unknown function |
| UHGV-1356435_30 | eggNOG-mapper | 1415775.U729_3168 | NA | NA |
| UHGV-1356435_30 | Structural annotation | PF08860 | NA | NA |
| UHGV-1356435_32 | KOfam | K01493 | comEB; dCMP deaminase [EC:3.5.4.12] | NA |
| UHGV-1356435_32 | PHROG | phrog_174 | dCMP deaminase | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_32 | UniRef90 | UniRef90_R6R9A3 | Putative dCMP deaminase | NA |
| UHGV-1356435_32 | eggNOG-mapper | 545243.BAEV01000028_gene663 | deaminase | NA |
| UHGV-1356435_32 | Pfam | PF00383 | Cytidine and deoxycytidylate deaminase zinc-binding region | dCMP_cyt_deam_1 |
| UHGV-1356435_32 | COG | COG2131 | Deoxycytidylate deaminase | NA |
| UHGV-1356435_32 | Structural annotation | PF00383, TIGR02571, COG2131 | NA | NA |
| UHGV-1356435_36 | KOfam | K07192 | FLOT; flotillin | NA |
| UHGV-1356435_36 | UniRef90 | UniRef90_A0A371J6N5 | Flotillin family protein | NA |
| UHGV-1356435_36 | eggNOG-mapper | 1301100.HG529329_gene4479 | Band 7 protein | NA |
| UHGV-1356435_36 | Pfam | PF01145 | SPFH domain / Band 7 family | Band_7 |
| UHGV-1356435_36 | Pfam | PF15975 | Flotillin | Flot |
| UHGV-1356435_36 | COG | COG2268 | NA | NA |
| UHGV-1356435_36 | Structural annotation | PF01145, MF_01562, NF008181, COG2268 | NA | NA |
| UHGV-1356435_38 | PHROG | phrog_298 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_38 | Pfam | PF12705 | PD-(D/E)XK nuclease superfamily | PDDEXK_1 |
| UHGV-1356435_38 | Structural annotation | PF12705, MF_03030, TIGR00372, COG2887 | NA | NA |
| UHGV-1356435_39 | KOfam | K07171 | mazF, ndoA, chpA; mRNA interferase MazF [EC:3.1.-.-] | NA |
| UHGV-1356435_39 | PHROG | phrog_1936 | MazF-like growth inhibitor | moron, auxiliary metabolic gene and host takeover |
| UHGV-1356435_39 | UniRef90 | UniRef90_A0A1C6FDH1 | mRNA interferase | NA |
| UHGV-1356435_39 | eggNOG-mapper | 926692.AZYG01000040_gene1502 | Toxic component of a toxin-antitoxin (TA) module | NA |
| UHGV-1356435_39 | Pfam | PF02452 | PemK-like, MazF-like toxin of type II toxin-antitoxin system | PemK_toxin |
| UHGV-1356435_39 | COG | COG2337 | mRNA-degrading endonuclease MazF, toxin component of the MazEF toxin-antitoxin module | NA |
| UHGV-1356435_41 | eggNOG-mapper | 658088.HMPREF0987_01134 | NA | NA |
| UHGV-1356435_43 | PHROG | phrog_93 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_43 | UniRef90 | UniRef90_A0A2U1JUK2 | Recombinase RecB | NA |
| UHGV-1356435_43 | eggNOG-mapper | 1158614.I592_02354 | Archaeal holliday junction resolvase (hjc) | NA |
| UHGV-1356435_43 | COG | COG1591 | Holliday junction resolvase Hjc, archaeal type | NA |
| UHGV-1356435_43 | Structural annotation | PF01870, MF_01490, NF002581, COG1591 | NA | NA |
| UHGV-1356435_48 | PHROG | phrog_3754 | NA | unknown function |
| UHGV-1356435_55 | PHROG | phrog_374 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_55 | eggNOG-mapper | 397291.C804_06294 | transposase activity | NA |
| UHGV-1356435_55 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-1356435_57 | PHROG | phrog_6244 | NA | unknown function |
| UHGV-1356435_57 | eggNOG-mapper | 908337.HMPREF9257_0560 | YqaJ-like viral recombinase domain | NA |
| UHGV-1356435_57 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-1356435_59 | PHROG | phrog_124 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_59 | UniRef90 | UniRef90_UPI001F43F7F0 | ATP-binding protein | NA |
| UHGV-1356435_59 | eggNOG-mapper | 646529.Desaci_1280 | AAA domain | NA |
| UHGV-1356435_59 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-1356435_59 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-1356435_59 | Structural annotation | PF13479, MF_00350, TIGR01618, COG2874 | NA | NA |
| UHGV-1356435_60 | Pfam | PF05037 | NA | DUF669 |
| UHGV-1356435_60 | Structural annotation | PF05037, MF_00292, NF038397, COG2053 | NA | NA |
| UHGV-1356435_61 | PHROG | phrog_1252 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_61 | UniRef90 | UniRef90_M5NWD7 | DNA-directed DNA polymerase | NA |
| UHGV-1356435_61 | eggNOG-mapper | 1274524.BSONL12_23100 | DNA polymerase elongation subunit (Family B) | NA |
| UHGV-1356435_61 | COG | COG0417 | DNA polymerase B elongation subunit | NA |
| UHGV-1356435_61 | Structural annotation | PF08490, MF_04100, TIGR00592, COG0417 | NA | NA |
| UHGV-1356435_62 | PHROG | phrog_761 | thymidylate kinase | other |
| UHGV-1356435_62 | Pfam | PF02223 | Thymidylate kinase | Thymidylate_kin |
| UHGV-1356435_63 | PHROG | phrog_12184 | nucleotide pyrophosphohydrolase | other |
| UHGV-1356435_63 | UniRef90 | UniRef90_A0A843GTV8 | dUTP diphosphatase | NA |
| UHGV-1356435_63 | Pfam | PF08761 | dUTPase | dUTPase_2 |
| UHGV-1356435_63 | Structural annotation | PF08761 | NA | NA |
| UHGV-1356435_65 | KOfam | K00560 | thyA, TYMS; thymidylate synthase [EC:2.1.1.45] | NA |
| UHGV-1356435_65 | PHROG | phrog_160 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_65 | UniRef90 | UniRef90_A0A6H2A3P2 | Putative thymidylate synthase | NA |
| UHGV-1356435_65 | eggNOG-mapper | 420246.GTNG_1671 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | NA |
| UHGV-1356435_65 | Pfam | PF00303 | Thymidylate synthase | Thymidylat_synt |
| UHGV-1356435_65 | COG | COG0207 | Thymidylate synthase | NA |
| UHGV-1356435_65 | Structural annotation | PF00303, MF_01686, TIGR03283, COG0207 | NA | NA |
| UHGV-1356435_71 | KOfam | K06919 | K06919; putative DNA primase/helicase | NA |
| UHGV-1356435_71 | PHROG | phrog_864 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1356435_71 | UniRef90 | UniRef90_UPI00156FE0C3 | phage/plasmid primase, P4 family | NA |
| UHGV-1356435_71 | eggNOG-mapper | 762983.HMPREF9444_01503 | D5 N terminal like | NA |
| UHGV-1356435_71 | Pfam | PF19263 | NA | DUF5906 |
| UHGV-1356435_71 | NCBIFam | TIGR01613.1 | phage/plasmid primase, P4 family | NA |
| UHGV-1356435_71 | COG | COG3378 | DNA primase, phage- or plasmid-associated | NA |
| UHGV-1356435_71 | Structural annotation | PF19263, PF08706, PF03288, PF09250, MF_04000, TIGR01613, COG3378 | NA | NA |
| UHGV-1356435_74 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-1356435_74 | PHROG | phrog_3717 | terminase large subunit | head and packaging |
| UHGV-1356435_74 | UniRef90 | UniRef90_UPI001A9034D2 | PBSX family phage terminase large subunit | NA |
| UHGV-1356435_74 | eggNOG-mapper | 445972.ANACOL_01839 | Phage terminase, large subunit, PBSX family | NA |
| UHGV-1356435_74 | Pfam | PF04466 | Phage terminase large subunit | Terminase_3 |
| UHGV-1356435_74 | Pfam | PF17288 | Terminase RNAseH like domain | Terminase_3C |
| UHGV-1356435_74 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-1356435_74 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-1356435_74 | Structural annotation | PF04466, PF17288, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1356435_77 | Structural annotation | PF13058 | NA | NA |
| UHGV-1356435_78 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-1356435_78 | UniRef90 | UniRef90_R6I230 | SPP1 family phage portal protein | NA |
| UHGV-1356435_78 | eggNOG-mapper | 1071073.KI530547_gene3808 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1356435_78 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-1356435_78 | Structural annotation | PF05133, MF_04120, TIGR01538, COG5518 | NA | NA |
| UHGV-1356435_82 | KOfam | K07097 | NA | NA |
| UHGV-1356435_82 | PHROG | phrog_4771 | DHH phosphoesterase | other |
| UHGV-1356435_82 | UniRef90 | UniRef90_A0A267MPB5 | Phosphohydrolase | NA |
| UHGV-1356435_82 | eggNOG-mapper | 406124.ACPC01000048_gene226 | phosphohydrolase (DHH superfamily) | NA |
| UHGV-1356435_82 | Pfam | PF02272 | DHHA1 domain | DHHA1 |
| UHGV-1356435_82 | COG | COG2404 | Oligoribonuclease NrnA/c-di-AMP phosphodiesterase DhhP, DHH superfamily | NA |
| UHGV-1356435_82 | Structural annotation | PF02272, MF_00207, TIGR00644, COG2404 | NA | NA |
| UHGV-1356435_83 | Structural annotation | PF14265 | NA | NA |
| UHGV-1356435_84 | UniRef90 | UniRef90_A0A2H5YHT6 | zf-trcl domain-containing protein | NA |
| UHGV-1356435_84 | eggNOG-mapper | 1034347.CAHJ01000084_gene1346 | Probable zinc-ribbon domain | NA |
| UHGV-1356435_84 | Pfam | PF13451 | Probable zinc-ribbon domain | zf-trcl |
| UHGV-1356435_84 | COG | COG0514 | Superfamily II DNA helicase RecQ | NA |
| UHGV-1356435_87 | PHROG | phrog_881 | holin | lysis |
| UHGV-1356435_87 | UniRef90 | UniRef90_A0A843HKU1 | Phage holin | NA |
| UHGV-1356435_87 | eggNOG-mapper | 742740.HMPREF9474_02251 | Putative phage holin Dp-1 | NA |
| UHGV-1356435_87 | Pfam | PF16938 | Putative phage holin Dp-1 | Phage_holin_Dp1 |
| UHGV-1356435_87 | Structural annotation | PF16938 | NA | NA |
| UHGV-1356435_88 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-1356435_88 | PHROG | phrog_7698 | endolysin | lysis |
| UHGV-1356435_88 | UniRef90 | UniRef90_A0A2A7A552 | SH3b domain-containing protein | NA |
| UHGV-1356435_88 | eggNOG-mapper | 742733.HMPREF9469_05022 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1356435_88 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-1356435_88 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-1356435_88 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1356435_88 | Structural annotation | PF01510, PF18342, PF08239, MF_04111, NF040670, NF008758, COG5632 | NA | NA |
| UHGV-1356435_93 | Pfam | PF13964 | Kelch motif | Kelch_6 |
| UHGV-1356435_95 | Pfam | PF04647 | Accessory gene regulator B | AgrB |
| UHGV-1356435_95 | Structural annotation | PF08281 | NA | NA |
| UHGV-1356435_96 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-1356435_96 | eggNOG-mapper | 476272.RUMHYD_01952 | NA | NA |
| UHGV-1356435_97 | eggNOG-mapper | 658655.HMPREF0988_00918 | NA | NA |
| UHGV-1356435_98 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1356435_98 | eggNOG-mapper | 476272.RUMHYD_01954 | NA | NA |
| UHGV-1356435_99 | UniRef90 | UniRef90_A0A316MV88 | BclA_C domain-containing protein | NA |
| UHGV-1356435_99 | Structural annotation | PF18573, NF033147 | NA | NA |