| UHGV-1365981_2 | PHROG | phrog_190 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1365981_2 | UniRef90 | UniRef90_UPI0006C2AC63 | NA | NA |
| UHGV-1365981_2 | eggNOG-mapper | 1226322.HMPREF1545_00295 | NA | NA |
| UHGV-1365981_2 | Pfam | PF06356 | NA | DUF1064 |
| UHGV-1365981_2 | Structural annotation | PF06356 | NA | NA |
| UHGV-1365981_3 | PHROG | phrog_374 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1365981_3 | eggNOG-mapper | 387344.LVIS_0713 | NA | NA |
| UHGV-1365981_5 | PHROG | phrog_2245 | nucleoside triphosphate pyrophosphohydrolase | other |
| UHGV-1365981_5 | UniRef90 | UniRef90_A0A4U9RLZ8 | NA | NA |
| UHGV-1365981_5 | eggNOG-mapper | 1567010.A0A0A7RU90_9VIRU | protein disulfide oxidoreductase activity | NA |
| UHGV-1365981_9 | UniRef90 | UniRef90_A0A4Y9VSI4 | Methyltransferase | NA |
| UHGV-1365981_9 | eggNOG-mapper | 1268240.ATFI01000007_gene431 | DNA methylase | NA |
| UHGV-1365981_9 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1365981_10 | KOfam | K07319 | yhdJ; adenine-specific DNA-methyltransferase [EC:2.1.1.72] | NA |
| UHGV-1365981_10 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-1365981_10 | UniRef90 | UniRef90_A0A413FXK5 | Methyltransferase | NA |
| UHGV-1365981_10 | eggNOG-mapper | 1378168.N510_02840 | DNA methylase | NA |
| UHGV-1365981_10 | PADLOC | MTase_II_00172 | Type II methyltransferase | RM |
| UHGV-1365981_10 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1365981_10 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1365981_11 | PHROG | phrog_3584 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-1365981_11 | eggNOG-mapper | 537013.CLOSTMETH_02141 | NA | NA |
| UHGV-1365981_11 | Structural annotation | PF21578, MF_00360 | NA | NA |
| UHGV-1365981_12 | eggNOG-mapper | 1297617.JPJD01000059_gene2640 | NA | NA |
| UHGV-1365981_12 | Structural annotation | PF06530, TIGR01636 | NA | NA |
| UHGV-1365981_13 | PHROG | phrog_119 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1365981_13 | UniRef90 | UniRef90_A0A174XSZ8 | Prophage LambdaBa04, GP54 | NA |
| UHGV-1365981_13 | eggNOG-mapper | 1235793.C809_01915 | HNH endonuclease | NA |
| UHGV-1365981_13 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-1365981_13 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-1365981_14 | PHROG | phrog_1066 | NA | unknown function |
| UHGV-1365981_14 | eggNOG-mapper | 1341151.ASZU01000004_gene265 | NA | NA |
| UHGV-1365981_14 | Structural annotation | PF05119, TIGR01558 | NA | NA |
| UHGV-1365981_15 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-1365981_15 | UniRef90 | UniRef90_UPI00148AEB9A | terminase large subunit | NA |
| UHGV-1365981_15 | eggNOG-mapper | 1203606.HMPREF1526_00981 | Terminase | NA |
| UHGV-1365981_15 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-1365981_15 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-1365981_15 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-1365981_15 | Structural annotation | PF20441, PF03354, MF_04145, TIGR01547, COG4626 | NA | NA |
| UHGV-1365981_16 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-1365981_16 | UniRef90 | UniRef90_C4GAS6 | Putative phage portal protein, HK97 family | NA |
| UHGV-1365981_16 | eggNOG-mapper | 626523.GCWU000342_01027 | Portal protein | NA |
| UHGV-1365981_16 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-1365981_16 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-1365981_16 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-1365981_17 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-1365981_17 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-1365981_17 | UniRef90 | UniRef90_UPI0018979DC8 | Clp protease ClpP | NA |
| UHGV-1365981_17 | eggNOG-mapper | 1280689.AUJC01000011_gene1520 | Belongs to the peptidase S14 family | NA |
| UHGV-1365981_17 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-1365981_17 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-1365981_17 | Structural annotation | PF00574, MF_00444, NF011090, COG0740 | NA | NA |
| UHGV-1365981_18 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-1365981_18 | UniRef90 | UniRef90_UPI00189AE5FE | phage major capsid protein | NA |
| UHGV-1365981_18 | eggNOG-mapper | 1280689.AUJC01000011_gene1521 | Phage major capsid protein, HK97 family | NA |
| UHGV-1365981_18 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-1365981_18 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-1365981_18 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-1365981_18 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1365981_19 | PHROG | phrog_5223 | neck protein | connector |
| UHGV-1365981_19 | UniRef90 | UniRef90_E6MGY0 | Putative phage DNA packaging protein | NA |
| UHGV-1365981_19 | eggNOG-mapper | 887929.HMP0721_1264 | NA | NA |
| UHGV-1365981_20 | PHROG | phrog_1951 | head-tail adaptor | connector |
| UHGV-1365981_20 | UniRef90 | UniRef90_A0A1F8UNT5 | Phage head-tail adapter protein | NA |
| UHGV-1365981_20 | eggNOG-mapper | 1094508.Tsac_2422 | Phage head-tail joining protein | NA |
| UHGV-1365981_20 | Pfam | PF05521 | Phage head-tail joining protein | Phage_H_T_join |
| UHGV-1365981_20 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-1365981_20 | COG | COG5614 | Phage head-tail adaptor | NA |
| UHGV-1365981_20 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-1365981_21 | eggNOG-mapper | 1487921.DP68_11350 | NA | NA |
| UHGV-1365981_21 | Structural annotation | PF05657 | NA | NA |
| UHGV-1365981_22 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-1365981_22 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-1365981_23 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-1365981_23 | UniRef90 | UniRef90_S0FUN2 | Phage major tail protein, phi13 family | NA |
| UHGV-1365981_23 | eggNOG-mapper | 1195236.CTER_5106 | phage major tail protein, phi13 family | NA |
| UHGV-1365981_23 | NCBIFam | TIGR01603.1 | major tail protein | NA |
| UHGV-1365981_23 | COG | COG5492 | NA | NA |
| UHGV-1365981_23 | Structural annotation | PF04630, TIGR01603, COG3498 | NA | NA |
| UHGV-1365981_24 | Structural annotation | PF11836 | NA | NA |
| UHGV-1365981_25 | PHROG | phrog_8462 | tail length tape measure protein | tail |
| UHGV-1365981_25 | UniRef90 | UniRef90_UPI00098F054B | phage tail protein | NA |
| UHGV-1365981_25 | eggNOG-mapper | 1195236.CTER_5104 | nuclear chromosome segregation | NA |
| UHGV-1365981_25 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1365981_25 | Structural annotation | TIGR01760, NF033928 | NA | NA |
| UHGV-1365981_26 | PHROG | phrog_37549 | virion structural protein | head and packaging |
| UHGV-1365981_26 | UniRef90 | UniRef90_A0A3D0W045 | Fibronectin type-III domain-containing protein | NA |
| UHGV-1365981_26 | eggNOG-mapper | 1195236.CTER_5103 | NA | NA |
| UHGV-1365981_26 | Structural annotation | PF02010, PF06848, PF19266, MF_04116, NF033679, NF032891, TIGR01633, TIGR04488, COG3401, COG3499 | NA | NA |
| UHGV-1365981_27 | PHROG | phrog_26795 | NA | unknown function |
| UHGV-1365981_27 | eggNOG-mapper | 1195236.CTER_5102 | NA | NA |
| UHGV-1365981_27 | Structural annotation | PF14594, NF033848, COG4379 | NA | NA |
| UHGV-1365981_28 | Structural annotation | PF18614, MF_00085, NF003076, COG0231 | NA | NA |
| UHGV-1365981_30 | Structural annotation | PF10651 | NA | NA |
| UHGV-1365981_32 | PHROG | phrog_10898 | NA | unknown function |
| UHGV-1365981_32 | UniRef90 | UniRef90_A0A7U3NJT3 | Putative Ig-like domain-containing protein | NA |
| UHGV-1365981_32 | eggNOG-mapper | 717606.PaecuDRAFT_2136 | S-layer homology domain | NA |
| UHGV-1365981_32 | COG | COG1520 | Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat | NA |
| UHGV-1365981_32 | Structural annotation | PF19081, PF15418, MF_01905, NF032891, COG3291 | NA | NA |
| UHGV-1365981_33 | Structural annotation | PF16408, NF033510 | NA | NA |
| UHGV-1365981_34 | eggNOG-mapper | 1519439.JPJG01000060_gene1892 | Collagen triple helix repeat (20 copies) | NA |
| UHGV-1365981_34 | COG | COG3064 | Membrane protein TolA involved in colicin uptake | NA |
| UHGV-1365981_35 | PHROG | phrog_10993 | Hoc-like head decoration | head and packaging |
| UHGV-1365981_35 | UniRef90 | UniRef90_UPI000834AF98 | NA | NA |
| UHGV-1365981_35 | eggNOG-mapper | 742738.HMPREF9460_02534 | NA | NA |
| UHGV-1365981_35 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-1365981_35 | Structural annotation | PF19789 | NA | NA |
| UHGV-1365981_37 | eggNOG-mapper | 1519439.JPJG01000060_gene1895 | NA | NA |
| UHGV-1365981_37 | Structural annotation | PF10618 | NA | NA |
| UHGV-1365981_39 | PHROG | phrog_937 | hemolysin | other |
| UHGV-1365981_40 | PHROG | phrog_443 | holin | lysis |
| UHGV-1365981_40 | UniRef90 | UniRef90_A0A4R1QPE5 | Phage r1t holin | NA |
| UHGV-1365981_40 | eggNOG-mapper | 1469948.JPNB01000002_gene3855 | Putative lactococcus lactis phage r1t holin | NA |
| UHGV-1365981_40 | Pfam | PF16945 | Putative lactococcus lactis phage r1t holin | Phage_r1t_holin |
| UHGV-1365981_40 | Structural annotation | PF16945 | NA | NA |
| UHGV-1365981_41 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-1365981_41 | PHROG | phrog_1794 | amidase | lysis |
| UHGV-1365981_41 | UniRef90 | UniRef90_N1ZHY5 | N-acetylmuramoyl-L-alanine amidase domain-containing protein | NA |
| UHGV-1365981_41 | eggNOG-mapper | 97138.C820_00251 | Ami_2 | NA |
| UHGV-1365981_41 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-1365981_41 | COG | COG3023 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD | NA |
| UHGV-1365981_41 | Structural annotation | PF01510, MF_04111, NF008758, COG5632 | NA | NA |
| UHGV-1365981_42 | Structural annotation | PF02001, MF_00674, COG1342 | NA | NA |
| UHGV-1365981_44 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1365981_45 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-1365981_46 | UniRef90 | UniRef90_A0A8F0WD75 | RNA polymerase sigma factor/Ubiquitin-like protein | NA |
| UHGV-1365981_46 | eggNOG-mapper | 1378168.N510_03079 | NA | NA |
| UHGV-1365981_47 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-1365981_47 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-1365981_47 | UniRef90 | UniRef90_G9YSD9 | Resolvase protein | NA |
| UHGV-1365981_47 | eggNOG-mapper | 1408437.JNJN01000002_gene1420 | Resolvase, N terminal domain | NA |
| UHGV-1365981_47 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-1365981_47 | Pfam | PF07508 | Recombinase | Recombinase |
| UHGV-1365981_47 | Pfam | PF13408 | Recombinase zinc beta ribbon domain | Zn_ribbon_recom |
| UHGV-1365981_47 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-1365981_47 | Structural annotation | PF07508, PF00239, NF041201, COG1961 | NA | NA |
| UHGV-1365981_48 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1365981_48 | Structural annotation | PF12844, MF_00535, NF041677, COG1396 | NA | NA |
| UHGV-1365981_49 | PHROG | phrog_10292 | NA | unknown function |
| UHGV-1365981_49 | UniRef90 | UniRef90_A0A416W984 | TM2 domain-containing protein | NA |
| UHGV-1365981_49 | eggNOG-mapper | 537013.CLOSTMETH_02269 | TM2 domain | NA |
| UHGV-1365981_49 | Pfam | PF13240 | zinc-ribbon domain | zinc_ribbon_2 |
| UHGV-1365981_49 | Pfam | PF05154 | TM2 domain | TM2 |
| UHGV-1365981_49 | COG | COG2314 | NA | NA |
| UHGV-1365981_50 | eggNOG-mapper | 552398.HMPREF0866_02158 | NOG18738 non supervised orthologous group | NA |
| UHGV-1365981_50 | COG | COG2169 | Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains | NA |
| UHGV-1365981_50 | Structural annotation | PF02805 | NA | NA |
| UHGV-1365981_52 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-1365981_52 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1365981_52 | UniRef90 | UniRef90_A0A2U1BEG8 | Helix-turn-helix protein | NA |
| UHGV-1365981_52 | eggNOG-mapper | 445972.ANACOL_03315 | NA | NA |
| UHGV-1365981_52 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1365981_52 | Pfam | PF12844 | Helix-turn-helix domain | HTH_19 |
| UHGV-1365981_52 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1365981_52 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1365981_55 | eggNOG-mapper | 642492.Clole_0961 | NA | NA |
| UHGV-1365981_55 | Structural annotation | PF12286 | NA | NA |
| UHGV-1365981_56 | Structural annotation | PF10548 | NA | NA |
| UHGV-1365981_58 | Structural annotation | NF041247 | NA | NA |
| UHGV-1365981_63 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1365981_63 | PHROG | phrog_363 | DNA methyltransferase | other |
| UHGV-1365981_63 | UniRef90 | UniRef90_G4KRB8 | Cytosine-specific methyltransferase | NA |
| UHGV-1365981_63 | eggNOG-mapper | 693746.OBV_01900 | Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family | NA |
| UHGV-1365981_63 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-1365981_63 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1365981_63 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1365981_63 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1365981_63 | Structural annotation | PF00145, MF_00351, TIGR00675, COG0270 | NA | NA |
| UHGV-1365981_64 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1365981_64 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1365981_64 | UniRef90 | UniRef90_UPI001D087498 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-1365981_64 | eggNOG-mapper | 1408437.JNJN01000032_gene2312 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1365981_64 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-1365981_64 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1365981_64 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1365981_64 | Structural annotation | PF01507, MF_00063, NF010369, COG0175 | NA | NA |
| UHGV-1365981_65 | UniRef90 | UniRef90_A0A845MZZ9 | NA | NA |
| UHGV-1365981_65 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1365981_65 | Structural annotation | NF041588 | NA | NA |
| UHGV-1365981_66 | PHROG | phrog_3136 | NA | unknown function |
| UHGV-1365981_66 | UniRef90 | UniRef90_A0A843H9M8 | ASCH domain-containing protein | NA |
| UHGV-1365981_66 | COG | COG4933 | Predicted transcriptional regulator, contains an HTH and PUA-like domains | NA |
| UHGV-1365981_66 | Structural annotation | PF08819, MF_00684, NF008917, COG4933 | NA | NA |
| UHGV-1365981_67 | PHROG | phrog_38832 | NA | unknown function |
| UHGV-1365981_67 | eggNOG-mapper | 665956.HMPREF1032_00143 | NA | NA |