| UHGV-1381195_1 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-1381195_1 | PHROG | phrog_979 | terminase large subunit | head and packaging |
| UHGV-1381195_1 | UniRef90 | UniRef90_UPI001BB47C17 | terminase family protein | NA |
| UHGV-1381195_1 | eggNOG-mapper | 748224.HMPREF9436_01395 | Terminase-like family | NA |
| UHGV-1381195_1 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-1381195_1 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-1381195_1 | Structural annotation | PF20454, MF_04148, TIGR01547, COG5323 | NA | NA |
| UHGV-1381195_2 | PHROG | phrog_156 | portal protein | head and packaging |
| UHGV-1381195_2 | UniRef90 | UniRef90_A0A8D9UH10 | Portal protein | NA |
| UHGV-1381195_2 | eggNOG-mapper | 748224.HMPREF9436_02547 | NA | NA |
| UHGV-1381195_2 | Structural annotation | PF16510, MF_04120, TIGR01538, COG5518 | NA | NA |
| UHGV-1381195_3 | KOfam | K07584 | NA | NA |
| UHGV-1381195_3 | PHROG | phrog_4478 | peptidase | other |
| UHGV-1381195_3 | UniRef90 | UniRef90_A0A117KW78 | Ribosomal-processing cysteine protease Prp | NA |
| UHGV-1381195_3 | eggNOG-mapper | 273068.TTE0914 | Cysteine protease Prp | NA |
| UHGV-1381195_3 | Pfam | PF04327 | Cysteine protease Prp | Peptidase_Prp |
| UHGV-1381195_3 | COG | COG2868 | NA | NA |
| UHGV-1381195_3 | Structural annotation | PF04327, NF011125, COG2868 | NA | NA |
| UHGV-1381195_4 | PHROG | phrog_13908 | NA | unknown function |
| UHGV-1381195_4 | eggNOG-mapper | 1410650.JHWL01000003_gene2831 | NA | NA |
| UHGV-1381195_5 | PHROG | phrog_1357 | major head protein | head and packaging |
| UHGV-1381195_5 | UniRef90 | UniRef90_UPI001D02EBA7 | N4-gp56 family major capsid protein | NA |
| UHGV-1381195_5 | eggNOG-mapper | 1203606.HMPREF1526_02746 | NA | NA |
| UHGV-1381195_5 | Pfam | PF13252 | NA | DUF4043 |
| UHGV-1381195_5 | NCBIFam | TIGR04387.1 | N4-gp56 family major capsid protein | NA |
| UHGV-1381195_5 | Structural annotation | PF13252, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-1381195_7 | Structural annotation | PF10651 | NA | NA |
| UHGV-1381195_8 | PHROG | phrog_10993 | Hoc-like head decoration | head and packaging |
| UHGV-1381195_8 | UniRef90 | UniRef90_K1UI43 | NA | NA |
| UHGV-1381195_8 | eggNOG-mapper | 1121334.KB911071_gene1970 | NA | NA |
| UHGV-1381195_8 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-1381195_8 | Structural annotation | PF19789 | NA | NA |
| UHGV-1381195_9 | COG | COG4675 | Phage tail collar domain | NA |
| UHGV-1381195_9 | Structural annotation | PF20328, TIGR04362 | NA | NA |
| UHGV-1381195_10 | PHROG | phrog_37900 | NA | unknown function |
| UHGV-1381195_10 | UniRef90 | UniRef90_A0A3D2YEL7 | NA | NA |
| UHGV-1381195_10 | eggNOG-mapper | 552398.HMPREF0866_03098 | NA | NA |
| UHGV-1381195_10 | COG | COG3827 | Cell pole-organizing protein PopZ | NA |
| UHGV-1381195_10 | Structural annotation | PF19789 | NA | NA |
| UHGV-1381195_14 | PHROG | phrog_199 | holin | lysis |
| UHGV-1381195_14 | UniRef90 | UniRef90_K1UL76 | Holin, toxin secretion/phage lysis | NA |
| UHGV-1381195_14 | eggNOG-mapper | 411467.BACCAP_00280 | Bacteriophage holin family | NA |
| UHGV-1381195_14 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-1381195_14 | NCBIFam | TIGR01593.1 | toxin secretion/phage lysis holin | NA |
| UHGV-1381195_14 | COG | COG4824 | Phage-related holin (Lysis protein) | NA |
| UHGV-1381195_14 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-1381195_15 | KOfam | K08640 | E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] | NA |
| UHGV-1381195_15 | PHROG | phrog_18955 | NA | unknown function |
| UHGV-1381195_15 | UniRef90 | UniRef90_UPI001C035E39 | D-Ala-D-Ala carboxypeptidase family metallohydrolase | NA |
| UHGV-1381195_15 | eggNOG-mapper | 1235797.C816_04171 | Peptidase M15 | NA |
| UHGV-1381195_15 | Pfam | PF09992 | Phosphodiester glycosidase | NAGPA |
| UHGV-1381195_15 | Pfam | PF08291 | Peptidase M15 | Peptidase_M15_3 |
| UHGV-1381195_15 | COG | COG3108 | NA | NA |
| UHGV-1381195_15 | Structural annotation | PF09992, PF08291, COG4632, COG3108 | NA | NA |
| UHGV-1381195_16 | PHROG | phrog_12105 | NA | unknown function |
| UHGV-1381195_16 | eggNOG-mapper | 1226322.HMPREF1545_03850 | NA | NA |
| UHGV-1381195_17 | PHROG | phrog_511 | internal virion protein | head and packaging |
| UHGV-1381195_17 | UniRef90 | UniRef90_A0A8D9UH72 | Stabilization protein (Fragment) | NA |
| UHGV-1381195_17 | eggNOG-mapper | 1226322.HMPREF1545_00785 | NA | NA |
| UHGV-1381195_17 | Structural annotation | PF11134, TIGR03300, NF038126, COG1520 | NA | NA |
| UHGV-1381195_18 | Pfam | PF07889 | NA | DUF1664 |
| UHGV-1381195_19 | eggNOG-mapper | 1519439.JPJG01000060_gene1904 | NA | NA |
| UHGV-1381195_20 | PHROG | phrog_22978 | NA | unknown function |
| UHGV-1381195_20 | UniRef90 | UniRef90_A0A2V2FDI6 | MuF_C domain-containing protein | NA |
| UHGV-1381195_20 | eggNOG-mapper | 1410650.JHWL01000003_gene2814 | NA | NA |
| UHGV-1381195_21 | UniRef90 | UniRef90_A0A8D9PDQ3 | ECF sigma factor | NA |
| UHGV-1381195_21 | Structural annotation | PF04545, MF_00674, NF009179, COG1342 | NA | NA |
| UHGV-1381195_23 | PHROG | phrog_22984 | NA | unknown function |
| UHGV-1381195_24 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1381195_24 | eggNOG-mapper | 476272.RUMHYD_01770 | NA | NA |
| UHGV-1381195_25 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-1381195_26 | eggNOG-mapper | 1408437.JNJN01000043_gene801 | NA | NA |
| UHGV-1381195_27 | KOfam | K14059 | int; integrase | NA |
| UHGV-1381195_27 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1381195_27 | UniRef90 | UniRef90_UPI001EDE32BF | site-specific integrase | NA |
| UHGV-1381195_27 | eggNOG-mapper | 1226322.HMPREF1545_00144 | Belongs to the 'phage' integrase family | NA |
| UHGV-1381195_27 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1381195_27 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1381195_27 | Structural annotation | PF00589, PF12167, MF_02055, NF040815, COG4974 | NA | NA |
| UHGV-1381195_28 | Structural annotation | PF01381, MF_02017, TIGR03070, COG3655 | NA | NA |
| UHGV-1381195_30 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1381195_30 | UniRef90 | UniRef90_A0A845R7R6 | XRE family transcriptional regulator | NA |
| UHGV-1381195_30 | eggNOG-mapper | 411460.RUMTOR_02056 | Bacteriophage CI repressor helix-turn-helix domain | NA |
| UHGV-1381195_30 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1381195_30 | COG | COG3093 | Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain | NA |
| UHGV-1381195_33 | UniRef90 | UniRef90_A0A7X9BRV4 | Helix-turn-helix transcriptional regulator | NA |
| UHGV-1381195_33 | eggNOG-mapper | 411473.RUMCAL_01355 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-1381195_33 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1381195_33 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-1381195_34 | UniRef90 | UniRef90_UPI001EDEB2FF | helix-turn-helix domain-containing protein | NA |
| UHGV-1381195_34 | Structural annotation | PF13560, MF_00535, NF041951, COG3655 | NA | NA |
| UHGV-1381195_37 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-1381195_37 | Structural annotation | PF14354, TIGR03655 | NA | NA |
| UHGV-1381195_39 | PHROG | phrog_4973 | NA | unknown function |
| UHGV-1381195_39 | UniRef90 | UniRef90_A0A3D3Y5F2 | DNA-binding protein | NA |
| UHGV-1381195_39 | eggNOG-mapper | 935261.JAGL01000009_gene1175 | Helix-turn-helix domain | NA |
| UHGV-1381195_39 | Pfam | PF14090 | Helix-turn-helix domain | HTH_39 |
| UHGV-1381195_39 | Structural annotation | PF14090, MF_01586, TIGR00373, COG5625 | NA | NA |
| UHGV-1381195_41 | PHROG | phrog_7838 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1381195_41 | UniRef90 | UniRef90_A0A8D9UGW3 | DNA repair protein RAD52-like protein | NA |
| UHGV-1381195_41 | eggNOG-mapper | 742767.HMPREF9456_02052 | NA | NA |
| UHGV-1381195_41 | Structural annotation | PF04098, TIGR00607, COG4380 | NA | NA |
| UHGV-1381195_42 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-1381195_42 | UniRef90 | UniRef90_A0A8D9PDS2 | NinB protein | NA |
| UHGV-1381195_42 | eggNOG-mapper | 445972.ANACOL_01825 | NA | NA |
| UHGV-1381195_42 | Pfam | PF05772 | NinB protein | NinB |
| UHGV-1381195_42 | Structural annotation | PF05772 | NA | NA |
| UHGV-1381195_43 | PHROG | phrog_7370 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1381195_43 | UniRef90 | UniRef90_UPI001C122365 | HNH endonuclease | NA |
| UHGV-1381195_43 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-1381195_44 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-1381195_44 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1381195_44 | UniRef90 | UniRef90_A0A1Q6RGI0 | Single-stranded DNA-binding protein | NA |
| UHGV-1381195_44 | eggNOG-mapper | 1007096.BAGW01000023_gene151 | Single-strand binding protein family | NA |
| UHGV-1381195_44 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-1381195_44 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-1381195_44 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-1381195_44 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-1381195_44 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-1381195_45 | PHROG | phrog_2149 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-1381195_45 | UniRef90 | UniRef90_A0A417QFV0 | Transcriptional regulator | NA |
| UHGV-1381195_45 | eggNOG-mapper | 742740.HMPREF9474_03117 | NA | NA |
| UHGV-1381195_45 | Structural annotation | PF01978, NF000243, COG0735 | NA | NA |
| UHGV-1381195_47 | KOfam | K01160 | rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10] | NA |
| UHGV-1381195_47 | PHROG | phrog_140 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1381195_47 | UniRef90 | UniRef90_K1T7H8 | Endodeoxyribonuclease RusA family protein | NA |
| UHGV-1381195_47 | eggNOG-mapper | 318464.IO99_00510 | Endodeoxyribonuclease RusA | NA |
| UHGV-1381195_47 | Pfam | PF05866 | Endodeoxyribonuclease RusA | RusA |
| UHGV-1381195_47 | COG | COG4570 | Holliday junction resolvase RusA (prophage-encoded endonuclease) | NA |
| UHGV-1381195_49 | PHROG | phrog_474 | phosphofructokinase | other |
| UHGV-1381195_49 | UniRef90 | UniRef90_A0A2V2EHL9 | NA | NA |
| UHGV-1381195_49 | eggNOG-mapper | 1203606.HMPREF1526_00237 | NA | NA |
| UHGV-1381195_49 | Pfam | PF19905 | NA | DUF6378 |
| UHGV-1381195_49 | Structural annotation | PF19905 | NA | NA |
| UHGV-1381195_50 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1381195_50 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1381195_50 | UniRef90 | UniRef90_A0A6N2RVG9 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1381195_50 | eggNOG-mapper | 755731.Clo1100_3438 | Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family | NA |
| UHGV-1381195_50 | PADLOC | oMTase_00004 | orphan methyltransferase | RM |
| UHGV-1381195_50 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1381195_50 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1381195_50 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1381195_51 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1381195_52 | PHROG | phrog_38832 | NA | unknown function |
| UHGV-1381195_52 | eggNOG-mapper | 665956.HMPREF1032_00143 | NA | NA |
| UHGV-1381195_52 | Structural annotation | PF07073 | NA | NA |
| UHGV-1381195_54 | PHROG | phrog_599 | Lar-like restriction alleviation protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-1381195_54 | UniRef90 | UniRef90_UPI001D08B1AD | Lar family restriction alleviation protein | NA |
| UHGV-1381195_54 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-1381195_54 | NCBIFam | TIGR03655.1 | Lar family restriction alleviation protein | NA |
| UHGV-1381195_54 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-1381195_57 | KOfam | K02647 | cdaR; carbohydrate diacid regulator | NA |
| UHGV-1381195_57 | UniRef90 | UniRef90_UPI00164DE10C | helix-turn-helix domain-containing protein | NA |
| UHGV-1381195_57 | eggNOG-mapper | 411459.RUMOBE_03347 | PucR C-terminal helix-turn-helix domain | NA |
| UHGV-1381195_57 | Pfam | PF13556 | PucR C-terminal helix-turn-helix domain | HTH_30 |
| UHGV-1381195_57 | COG | COG3835 | Sugar diacid utilization regulator CdaR | NA |
| UHGV-1381195_57 | Structural annotation | PF13556, COG2771 | NA | NA |
| UHGV-1381195_58 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1381195_58 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1381195_58 | UniRef90 | UniRef90_A0A8D9PDC4 | Repressor protein | NA |
| UHGV-1381195_58 | eggNOG-mapper | 351627.Csac_2097 | PFAM helix-turn-helix domain protein | NA |
| UHGV-1381195_58 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1381195_58 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-1381195_58 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1381195_59 | PHROG | phrog_872 | NA | unknown function |
| UHGV-1381195_59 | UniRef90 | UniRef90_A0A8J6M9F5 | NA | NA |
| UHGV-1381195_59 | eggNOG-mapper | 1519439.JPJG01000060_gene1880 | NA | NA |
| UHGV-1381195_59 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-1381195_59 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-1381195_59 | Structural annotation | PF11195 | NA | NA |
| UHGV-1381195_60 | PHROG | phrog_606 | terminase small subunit | head and packaging |
| UHGV-1381195_60 | UniRef90 | UniRef90_UPI00195648BB | DNA-packaging protein | NA |
| UHGV-1381195_60 | eggNOG-mapper | 397290.C810_05185 | DNA-packaging protein gp3 | NA |
| UHGV-1381195_60 | Pfam | PF16677 | DNA-packaging protein gp3 | GP3_package |
| UHGV-1381195_60 | Structural annotation | PF16677 | NA | NA |
| UHGV-1381195_61 | PHROG | phrog_979 | terminase large subunit | head and packaging |
| UHGV-1381195_61 | UniRef90 | UniRef90_A0A4Q3IUC9 | Terminase (Fragment) | NA |
| UHGV-1381195_61 | eggNOG-mapper | 748224.HMPREF9436_01395 | Terminase-like family | NA |
| UHGV-1381195_61 | COG | COG1783 | Phage terminase large subunit | NA |