| UHGV-1386951_1 | UniRef90 | UniRef90_A0A415MEL8 | Type II toxin-antitoxin system HicA family toxin | NA |
| UHGV-1386951_1 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-1386951_1 | Structural annotation | PF07927, COG1724 | NA | NA |
| UHGV-1386951_6 | Structural annotation | PF19108 | NA | NA |
| UHGV-1386951_10 | PHROG | phrog_4264 | NA | unknown function |
| UHGV-1386951_10 | eggNOG-mapper | 442493.A8E2H1_BPPHE | NA | NA |
| UHGV-1386951_13 | PHROG | phrog_9027 | NA | unknown function |
| UHGV-1386951_15 | eggNOG-mapper | 411467.BACCAP_03927 | NA | NA |
| UHGV-1386951_18 | Structural annotation | PF06257, COG4466 | NA | NA |
| UHGV-1386951_23 | KOfam | K07729 | K07729; putative transcriptional regulator | NA |
| UHGV-1386951_23 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1386951_23 | UniRef90 | UniRef90_A0A3R6RE88 | XRE family transcriptional regulator | NA |
| UHGV-1386951_23 | eggNOG-mapper | 665956.HMPREF1032_03117 | helix-turn-helix | NA |
| UHGV-1386951_23 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1386951_23 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1386951_23 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1386951_23 | Structural annotation | PF01381, MF_00535, NF041951, COG1396 | NA | NA |
| UHGV-1386951_24 | KOfam | K07729 | K07729; putative transcriptional regulator | NA |
| UHGV-1386951_24 | PHROG | phrog_3 | transcriptional repressor | transcription regulation |
| UHGV-1386951_24 | UniRef90 | UniRef90_A0A3R6QTL5 | XRE family transcriptional regulator | NA |
| UHGV-1386951_24 | eggNOG-mapper | 1219626.HMPREF1639_06590 | Transcriptional | NA |
| UHGV-1386951_24 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1386951_24 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-1386951_25 | PHROG | phrog_463 | anti-repressor | transcription regulation |
| UHGV-1386951_25 | UniRef90 | UniRef90_S2Y4H5 | Bro-N domain-containing protein | NA |
| UHGV-1386951_25 | eggNOG-mapper | 411490.ANACAC_00813 | BRO family, N-terminal domain | NA |
| UHGV-1386951_25 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-1386951_25 | Pfam | PF10552 | ORF6C domain | ORF6C |
| UHGV-1386951_25 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-1386951_25 | Structural annotation | PF10552, PF02498, TIGR02681, COG3617 | NA | NA |
| UHGV-1386951_31 | KOfam | K03733 | xerC; integrase/recombinase XerC | NA |
| UHGV-1386951_31 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1386951_31 | UniRef90 | UniRef90_A0A3E2NBA5 | Tyr recombinase domain-containing protein | NA |
| UHGV-1386951_31 | eggNOG-mapper | 411470.RUMGNA_00044 | Belongs to the 'phage' integrase family | NA |
| UHGV-1386951_31 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1386951_31 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-1386951_31 | Structural annotation | PF00589, MF_01808, NF003462, COG4974 | NA | NA |
| UHGV-1386951_32 | Structural annotation | PF07878, NF041793, COG4453 | NA | NA |
| UHGV-1386951_33 | KOfam | K07171 | mazF, ndoA, chpA; mRNA interferase MazF [EC:3.1.-.-] | NA |
| UHGV-1386951_33 | PHROG | phrog_1936 | MazF-like growth inhibitor | moron, auxiliary metabolic gene and host takeover |
| UHGV-1386951_33 | UniRef90 | UniRef90_A0A414ZR29 | Type II toxin-antitoxin system PemK/MazF family toxin | NA |
| UHGV-1386951_33 | eggNOG-mapper | 397291.C804_00995 | Toxic component of a toxin-antitoxin (TA) module | NA |
| UHGV-1386951_33 | Pfam | PF02452 | PemK-like, MazF-like toxin of type II toxin-antitoxin system | PemK_toxin |
| UHGV-1386951_33 | COG | COG2337 | mRNA-degrading endonuclease MazF, toxin component of the MazEF toxin-antitoxin module | NA |
| UHGV-1386951_33 | Structural annotation | PF02452, NF007386, COG2337 | NA | NA |
| UHGV-1386951_36 | KOfam | K03091 | sigH; RNA polymerase sporulation-specific sigma factor | NA |
| UHGV-1386951_36 | UniRef90 | UniRef90_R0AZ17 | Sigma70_r2 domain-containing protein | NA |
| UHGV-1386951_36 | eggNOG-mapper | 742735.HMPREF9467_00837 | Sigma-70 region 2 | NA |
| UHGV-1386951_36 | Structural annotation | PF08281, MF_02064, NF006158, COG1191 | NA | NA |
| UHGV-1386951_37 | UniRef90 | UniRef90_A0A3A8ZWH6 | NA | NA |
| UHGV-1386951_37 | eggNOG-mapper | 1235800.C819_00449 | NA | NA |
| UHGV-1386951_37 | Structural annotation | PF14072, MF_02015, NF041060, COG1479 | NA | NA |
| UHGV-1386951_40 | Structural annotation | PF13291, MF_01054, NF010078, COG2061 | NA | NA |
| UHGV-1386951_41 | PHROG | phrog_36365 | NA | unknown function |
| UHGV-1386951_41 | eggNOG-mapper | 476272.RUMHYD_01925 | NA | NA |
| UHGV-1386951_42 | PHROG | phrog_9653 | NA | unknown function |
| UHGV-1386951_42 | UniRef90 | UniRef90_UPI001D012866 | PcfJ domain-containing protein | NA |
| UHGV-1386951_42 | eggNOG-mapper | 397291.C804_00957 | PcfJ-like protein | NA |
| UHGV-1386951_42 | Pfam | PF14284 | PcfJ-like protein | PcfJ |
| UHGV-1386951_42 | Structural annotation | PF14284 | NA | NA |
| UHGV-1386951_43 | PHROG | phrog_9910 | NA | unknown function |
| UHGV-1386951_43 | Structural annotation | PF13973, COG4481 | NA | NA |
| UHGV-1386951_44 | KOfam | K07074 | NA | NA |
| UHGV-1386951_44 | PHROG | phrog_388 | nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_44 | UniRef90 | UniRef90_A0A414ZR22 | Nucleotidyltransferase | NA |
| UHGV-1386951_44 | eggNOG-mapper | 1235802.C823_04709 | Predicted nucleotidyltransferase | NA |
| UHGV-1386951_44 | Pfam | PF10127 | RNA repair pathway DNA polymerase beta family | RlaP |
| UHGV-1386951_44 | COG | COG3541 | Predicted nucleotidyltransferase YcgL | NA |
| UHGV-1386951_44 | Structural annotation | PF10127, NF000181, COG3541 | NA | NA |
| UHGV-1386951_45 | eggNOG-mapper | 1235802.C823_04708 | NA | NA |
| UHGV-1386951_46 | KOfam | K00974 | cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] | NA |
| UHGV-1386951_46 | PHROG | phrog_2244 | tRNA nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_46 | UniRef90 | UniRef90_A0A414ZR40 | HD domain-containing protein | NA |
| UHGV-1386951_46 | eggNOG-mapper | 742735.HMPREF9467_00849 | NA | NA |
| UHGV-1386951_46 | Pfam | PF01743 | Poly A polymerase head domain | PolyA_pol |
| UHGV-1386951_46 | Pfam | PF12627 | Probable RNA and SrmB- binding site of polymerase A | PolyA_pol_RNAbd |
| UHGV-1386951_46 | Pfam | PF13735 | tRNA nucleotidyltransferase domain 2 putative | tRNA_NucTran2_2 |
| UHGV-1386951_46 | NCBIFam | NF009814.0 | CCA tRNA nucleotidyltransferase | NA |
| UHGV-1386951_46 | COG | COG0617 | tRNA nucleotidyltransferase/poly(A) polymerase | NA |
| UHGV-1386951_46 | Structural annotation | PF01743, PF13735, PF12627, MF_01263, TIGR02692, COG0617 | NA | NA |
| UHGV-1386951_47 | KOfam | K12410 | npdA; NAD-dependent deacetylase [EC:2.3.1.286] | NA |
| UHGV-1386951_47 | PHROG | phrog_2162 | Sir2 (NAD-dependent deacetylase) | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_47 | UniRef90 | UniRef90_A0A414ZR36 | NAD-dependent protein deacylase | NA |
| UHGV-1386951_47 | eggNOG-mapper | 1410650.JHWL01000027_gene2262 | Sir2 family | NA |
| UHGV-1386951_47 | Pfam | PF02146 | Sir2 family | SIR2 |
| UHGV-1386951_47 | NCBIFam | NF001752.0 | NAD-dependent protein deacylase | NA |
| UHGV-1386951_47 | COG | COG0846 | NAD-dependent protein deacetylase, SIR2 family | NA |
| UHGV-1386951_47 | Structural annotation | PF02146, MF_01968, NF001752, COG0846 | NA | NA |
| UHGV-1386951_48 | PHROG | phrog_1649 | metallo-phosphoesterase | other |
| UHGV-1386951_48 | UniRef90 | UniRef90_A0A416U1X6 | Metallophosphatase | NA |
| UHGV-1386951_48 | eggNOG-mapper | 397291.C804_00930 | NA | NA |
| UHGV-1386951_48 | COG | COG1409 | 3',5'-cyclic AMP phosphodiesterase CpdA | NA |
| UHGV-1386951_48 | Structural annotation | PF14582, MF_00905, TIGR03729, COG2129 | NA | NA |
| UHGV-1386951_50 | eggNOG-mapper | 1163671.JAGI01000002_gene1270 | NA | NA |
| UHGV-1386951_52 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1386951_52 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1386951_52 | UniRef90 | UniRef90_UPI00156E4CBF | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1386951_52 | eggNOG-mapper | 1121115.AXVN01000007_gene3542 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1386951_52 | PADLOC | oMTase_00023 | orphan methyltransferase | RM |
| UHGV-1386951_52 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1386951_52 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1386951_52 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1386951_52 | Structural annotation | PF00145, TIGR00675, COG0270 | NA | NA |
| UHGV-1386951_54 | UniRef90 | UniRef90_R9JN75 | NA | NA |
| UHGV-1386951_54 | eggNOG-mapper | 397291.C804_01014 | NA | NA |
| UHGV-1386951_54 | Pfam | PF10021 | Microbial-type PARG, catalytic domain | PARG_cat_microb |
| UHGV-1386951_54 | NCBIFam | TIGR02452.1 | TIGR02452 family protein | NA |
| UHGV-1386951_54 | COG | COG4295 | NA | NA |
| UHGV-1386951_54 | Structural annotation | PF10021, MF_01205, TIGR02452, COG4295 | NA | NA |
| UHGV-1386951_58 | PHROG | phrog_35094 | NA | unknown function |
| UHGV-1386951_58 | eggNOG-mapper | 547228.M4ZRU5_9CAUD | NA | NA |
| UHGV-1386951_66 | eggNOG-mapper | 742735.HMPREF9467_00871 | NA | NA |
| UHGV-1386951_70 | Structural annotation | PF15958 | NA | NA |
| UHGV-1386951_75 | PHROG | phrog_20092 | NA | unknown function |
| UHGV-1386951_80 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-1386951_80 | UniRef90 | UniRef90_A0A374DWC7 | Phosphoesterase | NA |
| UHGV-1386951_80 | eggNOG-mapper | 1514668.JOOA01000002_gene2369 | nucleotidyltransferase activity | NA |
| UHGV-1386951_80 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-1386951_80 | COG | COG4186 | NA | NA |
| UHGV-1386951_80 | Structural annotation | PF12850, MF_00575, TIGR04123, COG4186 | NA | NA |
| UHGV-1386951_81 | Structural annotation | PF06034 | NA | NA |
| UHGV-1386951_82 | Structural annotation | TIGR04550 | NA | NA |
| UHGV-1386951_84 | PHROG | phrog_4334 | NA | unknown function |
| UHGV-1386951_84 | eggNOG-mapper | 1211640.K4JUX1_9CAUD | NA | NA |
| UHGV-1386951_86 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1386951_86 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-1386951_86 | UniRef90 | UniRef90_A0A373Q5C4 | Methyltransferase | NA |
| UHGV-1386951_86 | eggNOG-mapper | 1122243.KB903771_gene1539 | DNA methylase | NA |
| UHGV-1386951_86 | PADLOC | MTase_II_00157 | Type II methyltransferase | RM |
| UHGV-1386951_86 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1386951_86 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1386951_86 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-1386951_91 | PHROG | phrog_5848 | NA | unknown function |
| UHGV-1386951_91 | UniRef90 | UniRef90_UPI0018A09237 | NA | NA |
| UHGV-1386951_91 | eggNOG-mapper | 180332.JTGN01000008_gene4124 | NA | NA |
| UHGV-1386951_91 | Structural annotation | PF11195, PF14359, COG3613 | NA | NA |
| UHGV-1386951_92 | PHROG | phrog_774 | NA | unknown function |
| UHGV-1386951_92 | eggNOG-mapper | 397290.C810_05225 | NA | NA |
| UHGV-1386951_93 | PHROG | phrog_1491 | tail fiber protein | tail |
| UHGV-1386951_93 | eggNOG-mapper | 397290.C810_01362 | NA | NA |
| UHGV-1386951_93 | Structural annotation | NF038048 | NA | NA |
| UHGV-1386951_95 | Structural annotation | PF18337, PF09633, NF008242 | NA | NA |
| UHGV-1386951_97 | PHROG | phrog_1366 | NA | unknown function |
| UHGV-1386951_97 | UniRef90 | UniRef90_UPI00195F9333 | ATP-binding protein | NA |
| UHGV-1386951_97 | eggNOG-mapper | 397291.C804_00928 | replication factor c | NA |
| UHGV-1386951_97 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-1386951_97 | COG | COG0470 | DNA polymerase III, delta prime subunit | NA |
| UHGV-1386951_97 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-1386951_98 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-1386951_98 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_98 | UniRef90 | UniRef90_UPI001570A7A9 | single-stranded DNA-binding protein | NA |
| UHGV-1386951_98 | eggNOG-mapper | 585394.RHOM_16640 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-1386951_98 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-1386951_98 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-1386951_98 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-1386951_98 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-1386951_98 | Structural annotation | PF00436, MF_00984, NF005580, COG0629 | NA | NA |
| UHGV-1386951_99 | Structural annotation | PF02069 | NA | NA |
| UHGV-1386951_100 | KOfam | K17680 | PEO1; twinkle protein [EC:5.6.2.3] | NA |
| UHGV-1386951_100 | PHROG | phrog_239 | DNA primase/helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_100 | UniRef90 | UniRef90_UPI001571416C | CHC2 zinc finger domain-containing protein | NA |
| UHGV-1386951_100 | eggNOG-mapper | 1256908.HMPREF0373_00663 | NA | NA |
| UHGV-1386951_100 | PADLOC | drt-cluster192 | DRT | DRT |
| UHGV-1386951_100 | Pfam | PF01807 | CHC2 zinc finger | zf-CHC2 |
| UHGV-1386951_100 | Pfam | PF13155 | Toprim-like | Toprim_2 |
| UHGV-1386951_100 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-1386951_100 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-1386951_100 | Structural annotation | PF03796, PF19898, MF_04154, TIGR03877, TIGR01391, COG0467, COG0358 | NA | NA |
| UHGV-1386951_101 | PHROG | phrog_99 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_101 | UniRef90 | UniRef90_A0A0V8QB59 | AP2/ERF domain-containing protein | NA |
| UHGV-1386951_101 | eggNOG-mapper | 86416.Clopa_2526 | AP2 domain | NA |
| UHGV-1386951_101 | Structural annotation | PF00847 | NA | NA |
| UHGV-1386951_102 | KOfam | K07465 | K07465; putative RecB family exonuclease | NA |
| UHGV-1386951_102 | PHROG | phrog_69 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_102 | UniRef90 | UniRef90_UPI00156D5BC0 | PD-(D/E)XK nuclease family protein | NA |
| UHGV-1386951_102 | eggNOG-mapper | 397291.C804_00923 | PD-(D/E)XK nuclease superfamily | NA |
| UHGV-1386951_102 | Pfam | PF12705 | PD-(D/E)XK nuclease superfamily | PDDEXK_1 |
| UHGV-1386951_102 | Structural annotation | PF12705, MF_03030, TIGR00372, COG2887 | NA | NA |
| UHGV-1386951_103 | KOfam | K02337 | dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] | NA |
| UHGV-1386951_103 | PHROG | phrog_405 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_103 | UniRef90 | UniRef90_A0A7X2T4Y3 | DNA-directed DNA polymerase | NA |
| UHGV-1386951_103 | eggNOG-mapper | 180332.JTGN01000008_gene4133 | DNA-directed DNA polymerase activity | NA |
| UHGV-1386951_103 | Pfam | PF02811 | PHP domain | PHP |
| UHGV-1386951_103 | Pfam | PF07733 | Bacterial DNA polymerase III alpha NTPase domain | DNA_pol3_alpha |
| UHGV-1386951_103 | Pfam | PF17657 | Bacterial DNA polymerase III alpha subunit finger domain | DNA_pol3_finger |
| UHGV-1386951_103 | Pfam | PF14579 | Helix-hairpin-helix motif | HHH_6 |
| UHGV-1386951_103 | COG | COG0587 | DNA polymerase III, alpha subunit | NA |
| UHGV-1386951_103 | Structural annotation | PF07733, PF02811, PF17657, PF06075, PF14579, MF_01902, TIGR00594, COG0587 | NA | NA |
| UHGV-1386951_104 | PHROG | phrog_3490 | ERCC4-type nuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_104 | UniRef90 | UniRef90_A0A414SKQ9 | ERCC4 domain-containing protein | NA |
| UHGV-1386951_104 | eggNOG-mapper | 1163671.JAGI01000002_gene1297 | ERCC4 domain | NA |
| UHGV-1386951_104 | Pfam | PF02732 | ERCC4 domain | ERCC4 |
| UHGV-1386951_104 | Structural annotation | PF02732, NF040956, COG1948 | NA | NA |
| UHGV-1386951_105 | PHROG | phrog_5889 | NA | unknown function |
| UHGV-1386951_105 | UniRef90 | UniRef90_A0A1C6AFR9 | Predicted HD-superfamily hydrolase | NA |
| UHGV-1386951_105 | eggNOG-mapper | 397291.C804_00919 | NA | NA |
| UHGV-1386951_105 | Pfam | PF20600 | Exodeoxyribonuclease X-like C-terminal | ExoX-like_C |
| UHGV-1386951_105 | Structural annotation | PF01966, MF_01427, NF010007, COG3481 | NA | NA |
| UHGV-1386951_108 | PHROG | phrog_1374 | NA | unknown function |
| UHGV-1386951_108 | eggNOG-mapper | 1519439.JPJG01000059_gene1913 | NA | NA |
| UHGV-1386951_111 | PHROG | phrog_2107 | thymidylate kinase | other |
| UHGV-1386951_111 | UniRef90 | UniRef90_A0A415ME95 | AAA_28 domain-containing protein | NA |
| UHGV-1386951_111 | eggNOG-mapper | 713586.KB900537_gene3221 | Involved in chromosome partitioning | NA |
| UHGV-1386951_111 | Pfam | PF13521 | AAA domain | AAA_28 |
| UHGV-1386951_111 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-1386951_111 | Structural annotation | PF13521, MF_01269, NF005923, COG3172 | NA | NA |
| UHGV-1386951_114 | Structural annotation | PF13291, MF_01054, NF010078, COG2061 | NA | NA |
| UHGV-1386951_115 | PHROG | phrog_6721 | NA | unknown function |
| UHGV-1386951_115 | eggNOG-mapper | 1235802.C823_04642 | NA | NA |
| UHGV-1386951_115 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-1386951_118 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-1386951_118 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_118 | UniRef90 | UniRef90_A0A415ME28 | DNA ligase | NA |
| UHGV-1386951_118 | eggNOG-mapper | 742735.HMPREF9467_00906 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-1386951_118 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-1386951_118 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-1386951_118 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-1386951_118 | NCBIFam | NF005932.1 | NAD-dependent DNA ligase LigA | NA |
| UHGV-1386951_118 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1386951_118 | HAMAP | MF_01588 | DNA ligase [ligA] | NA |
| UHGV-1386951_118 | Structural annotation | PF01653, PF03120, PF00533, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-1386951_119 | UniRef90 | UniRef90_A0A1C6D809 | Bacterial SH3 domain | NA |
| UHGV-1386951_119 | eggNOG-mapper | 1282887.AUJG01000021_gene2183 | NA | NA |
| UHGV-1386951_119 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-1386951_119 | Structural annotation | PF18341, NF040670, COG3103 | NA | NA |
| UHGV-1386951_120 | UniRef90 | UniRef90_A0A1Y4UI86 | Serine kinase | NA |
| UHGV-1386951_120 | COG | COG1925 | HPr or related phosphotransfer protein | NA |
| UHGV-1386951_120 | Structural annotation | PF00381, NF010354, COG1925 | NA | NA |
| UHGV-1386951_121 | eggNOG-mapper | 742733.HMPREF9469_05051 | NA | NA |
| UHGV-1386951_122 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-1386951_122 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-1386951_122 | UniRef90 | UniRef90_A0A3R6MDL6 | Guanylate kinase | NA |
| UHGV-1386951_122 | eggNOG-mapper | 742735.HMPREF9467_00910 | Guanylate kinase homologues. | NA |
| UHGV-1386951_122 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-1386951_122 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-1386951_122 | Structural annotation | PF00625, MF_00328, TIGR03263, COG0194 | NA | NA |
| UHGV-1386951_123 | UniRef90 | UniRef90_A0A1C5WPM1 | Nucleoside 2-deoxyribosyltransferase | NA |
| UHGV-1386951_123 | eggNOG-mapper | 1235802.C823_04639 | NA | NA |
| UHGV-1386951_123 | Structural annotation | PF15891, MF_03036, TIGR03646, COG3613 | NA | NA |
| UHGV-1386951_127 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-1386951_127 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-1386951_127 | UniRef90 | UniRef90_UPI00164ABCD3 | ATP cone domain-containing protein | NA |
| UHGV-1386951_127 | eggNOG-mapper | 500635.MITSMUL_03099 | Ribonucleoside-triphosphate reductase | NA |
| UHGV-1386951_127 | Pfam | PF03477 | ATP cone domain | ATP-cone |
| UHGV-1386951_127 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-1386951_127 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-1386951_127 | Structural annotation | PF13597, PF03477, MF_00440, NF006732, COG1328 | NA | NA |
| UHGV-1386951_128 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-1386951_128 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-1386951_128 | UniRef90 | UniRef90_A0A349YTN4 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-1386951_128 | eggNOG-mapper | 411902.CLOBOL_02823 | anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-1386951_128 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-1386951_128 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-1386951_128 | Structural annotation | PF13597, TIGR02487, COG1328 | NA | NA |
| UHGV-1386951_129 | KOfam | K04068 | nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] | NA |
| UHGV-1386951_129 | PHROG | phrog_626 | anaerobic ribonucleotide reductase small subunit | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_129 | UniRef90 | UniRef90_UPI00164C57E6 | anaerobic ribonucleoside-triphosphate reductase activating protein | NA |
| UHGV-1386951_129 | eggNOG-mapper | 742735.HMPREF9467_00914 | Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine | NA |
| UHGV-1386951_129 | Pfam | PF13353 | 4Fe-4S single cluster domain | Fer4_12 |
| UHGV-1386951_129 | NCBIFam | TIGR02491.1 | anaerobic ribonucleoside-triphosphate reductase activating protein | NA |
| UHGV-1386951_129 | COG | COG0602 | Organic radical activating enzyme NrdG/QueE | NA |
| UHGV-1386951_129 | Structural annotation | PF13353, MF_02059, TIGR02491, COG0602 | NA | NA |
| UHGV-1386951_130 | eggNOG-mapper | 411470.RUMGNA_00009 | NA | NA |
| UHGV-1386951_130 | Structural annotation | PF18358, NF037951, COG4481 | NA | NA |
| UHGV-1386951_132 | PHROG | phrog_38239 | NA | unknown function |
| UHGV-1386951_132 | UniRef90 | UniRef90_A0A847QYE6 | Ferredoxin:thioredoxin reductase | NA |
| UHGV-1386951_132 | eggNOG-mapper | 1519439.JPJG01000022_gene567 | Ferredoxin thioredoxin reductase catalytic beta chain | NA |
| UHGV-1386951_132 | Structural annotation | NF041072, COG4802 | NA | NA |
| UHGV-1386951_133 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-1386951_133 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-1386951_133 | UniRef90 | UniRef90_A0A416DQT1 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | NA |
| UHGV-1386951_133 | eggNOG-mapper | 1280679.ATVX01000006_gene1594 | dUTPase | NA |
| UHGV-1386951_133 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-1386951_133 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-1386951_134 | Structural annotation | PF20063 | NA | NA |
| UHGV-1386951_135 | eggNOG-mapper | 397291.C804_03344 | Belongs to the 'phage' integrase family | NA |
| UHGV-1386951_135 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-1386951_136 | KOfam | K14059 | int; integrase | NA |
| UHGV-1386951_136 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1386951_136 | UniRef90 | UniRef90_UPI00195AF73B | tyrosine-type recombinase/integrase | NA |
| UHGV-1386951_136 | eggNOG-mapper | 397291.C804_03380 | DNA integration | NA |
| UHGV-1386951_136 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1386951_136 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1386951_138 | PHROG | phrog_937 | hemolysin | other |
| UHGV-1386951_139 | PHROG | phrog_7121 | tail fiber protein | tail |
| UHGV-1386951_139 | UniRef90 | UniRef90_UPI00164BA345 | tail fiber domain-containing protein | NA |
| UHGV-1386951_139 | eggNOG-mapper | 537007.BLAHAN_05239 | cellulose 1,4-beta-cellobiosidase activity | NA |
| UHGV-1386951_139 | Pfam | PF13884 | Chaperone of endosialidase | Peptidase_S74 |
| UHGV-1386951_139 | COG | COG5301 | Phage-related tail fiber protein | NA |
| UHGV-1386951_140 | PHROG | phrog_16573 | NA | unknown function |
| UHGV-1386951_140 | eggNOG-mapper | 33035.JPJF01000033_gene2261 | tail collar domain protein | NA |
| UHGV-1386951_140 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-1386951_140 | Pfam | PF03406 | Phage tail fibre repeat | Phage_fiber_2 |
| UHGV-1386951_140 | COG | COG4675 | Phage tail collar domain | NA |
| UHGV-1386951_141 | eggNOG-mapper | 742735.HMPREF9467_00730 | NA | NA |
| UHGV-1386951_141 | Pfam | PF20195 | Phage tail protein N-terminal domain | DUF6558 |
| UHGV-1386951_141 | Pfam | PF20753 | Phage tail C-terminal domain | DUF6558_C |
| UHGV-1386951_141 | Structural annotation | PF20195, PF20753, TIGR01633, COG4722 | NA | NA |
| UHGV-1386951_142 | eggNOG-mapper | 272562.CA_C1880 | NA | NA |
| UHGV-1386951_142 | Structural annotation | PF07761 | NA | NA |
| UHGV-1386951_143 | PHROG | phrog_7121 | tail fiber protein | tail |
| UHGV-1386951_143 | UniRef90 | UniRef90_A0A3A9GE41 | Peptidase S74 domain-containing protein | NA |
| UHGV-1386951_143 | eggNOG-mapper | 97139.C824_00231 | NA | NA |
| UHGV-1386951_143 | Pfam | PF13884 | Chaperone of endosialidase | Peptidase_S74 |
| UHGV-1386951_143 | Structural annotation | PF14594, TIGR01665, NF041249, COG4926 | NA | NA |