| UHGV-1410916_5 | KOfam | K03427 | hsdM; type I restriction enzyme M protein [EC:2.1.1.72] | NA |
| UHGV-1410916_5 | PHROG | phrog_5696 | NA | unknown function |
| UHGV-1410916_5 | UniRef90 | UniRef90_A0A6L5XAE6 | N-6 DNA methylase | NA |
| UHGV-1410916_5 | eggNOG-mapper | 1249997.JHZW01000002_gene58 | COG NOG31012 non supervised orthologous group | NA |
| UHGV-1410916_5 | PADLOC | MTase_I_00005 | Type I methyltransferase | RM |
| UHGV-1410916_5 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-1410916_5 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-1410916_5 | Structural annotation | COG0286 | NA | NA |
| UHGV-1410916_15 | KOfam | K23779 | sutR; XRE family transcriptional regulator, regulator of sulfur utilization | NA |
| UHGV-1410916_15 | PHROG | phrog_5823 | transcriptional regulator | transcription regulation |
| UHGV-1410916_15 | UniRef90 | UniRef90_A0A6N7GYP1 | Helix-turn-helix domain-containing protein | NA |
| UHGV-1410916_15 | eggNOG-mapper | 679937.Bcop_2150 | Helix-turn-helix domain | NA |
| UHGV-1410916_15 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1410916_15 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1410916_15 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1410916_15 | Structural annotation | PF13560, TIGR03070, COG1396 | NA | NA |
| UHGV-1410916_18 | Structural annotation | PF06289, COG1582 | NA | NA |
| UHGV-1410916_19 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-1410916_19 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1410916_19 | UniRef90 | UniRef90_A0A2L2WS96 | DNA ligase (NAD(+)) | NA |
| UHGV-1410916_19 | eggNOG-mapper | 234267.Acid_7765 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-1410916_19 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-1410916_19 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-1410916_19 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1410916_19 | Structural annotation | PF01653, PF03120, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-1410916_20 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-1410916_20 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-1410916_20 | UniRef90 | UniRef90_A0A095Z6L5 | AAA_31 domain-containing protein | NA |
| UHGV-1410916_20 | eggNOG-mapper | 1236504.HMPREF2132_02105 | CobQ CobB MinD ParA nucleotide binding domain | NA |
| UHGV-1410916_20 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-1410916_20 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-1410916_20 | Structural annotation | PF13614, MF_00533, NF041283, COG1192 | NA | NA |
| UHGV-1410916_21 | Structural annotation | PF07878, COG3905 | NA | NA |
| UHGV-1410916_22 | eggNOG-mapper | 483215.BACFIN_04764 | NA | NA |
| UHGV-1410916_22 | Structural annotation | PF12502, MF_02248 | NA | NA |
| UHGV-1410916_23 | UniRef90 | UniRef90_R6XMM2 | Putative initiator RepB protein | NA |
| UHGV-1410916_23 | eggNOG-mapper | 1235811.HMPREF0653_01552 | Initiator RepB protein | NA |
| UHGV-1410916_23 | Pfam | PF21205 | Initiator Rep protein, WH2 | Rep3_C |
| UHGV-1410916_23 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-1410916_23 | Structural annotation | PF20964, PF07112, NF010305, COG5527 | NA | NA |
| UHGV-1410916_26 | Structural annotation | PF17457 | NA | NA |
| UHGV-1410916_27 | Structural annotation | COG3655 | NA | NA |
| UHGV-1410916_29 | PHROG | phrog_255 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1410916_29 | UniRef90 | UniRef90_A0A355U3Z6 | NA | NA |
| UHGV-1410916_29 | eggNOG-mapper | 1236504.HMPREF2132_01690 | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease | NA |
| UHGV-1410916_29 | Pfam | PF16473 | 3'-5' exoribonuclease Rv2179c-like domain | Rv2179c-like |
| UHGV-1410916_29 | COG | COG0847 | DNA polymerase III, epsilon subunit or related 3'-5' exonuclease | NA |
| UHGV-1410916_29 | Structural annotation | PF16473, MF_00157, TIGR01298, COG5018 | NA | NA |
| UHGV-1410916_31 | UniRef90 | UniRef90_A0A096AGU9 | FHA domain-containing protein | NA |
| UHGV-1410916_31 | eggNOG-mapper | 1236504.HMPREF2132_01700 | DNA primase activity | NA |
| UHGV-1410916_31 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-1410916_31 | Structural annotation | PF05272, PF01807, MF_00974, MF_00016, NF005477, COG3378, COG0358 | NA | NA |
| UHGV-1410916_34 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-1410916_34 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-1410916_34 | UniRef90 | UniRef90_A0A7X6VW07 | Beta sliding clamp | NA |
| UHGV-1410916_34 | eggNOG-mapper | 869213.JCM21142_72564 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-1410916_34 | Pfam | PF00712 | DNA polymerase III beta subunit, N-terminal domain | DNA_pol3_beta |
| UHGV-1410916_34 | Pfam | PF02767 | DNA polymerase III beta subunit, central domain | DNA_pol3_beta_2 |
| UHGV-1410916_34 | Pfam | PF02768 | DNA polymerase III beta subunit, C-terminal domain | DNA_pol3_beta_3 |
| UHGV-1410916_34 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-1410916_34 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-1410916_36 | Structural annotation | PF08863 | NA | NA |
| UHGV-1410916_38 | PHROG | phrog_954 | DNA methyltransferase | other |
| UHGV-1410916_38 | UniRef90 | UniRef90_A0A3E5E9I6 | Class I SAM-dependent methyltransferase | NA |
| UHGV-1410916_38 | eggNOG-mapper | 1347393.HG726022_gene3574 | Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA | NA |
| UHGV-1410916_38 | PADLOC | MTase_II_00074 | Type II methyltransferase | RM |
| UHGV-1410916_38 | COG | COG1092 | 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI | NA |
| UHGV-1410916_39 | eggNOG-mapper | 1002367.HMPREF0673_02207 | NA | NA |
| UHGV-1410916_39 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1410916_40 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-1410916_40 | UniRef90 | UniRef90_A0A096B9T1 | Conjugal transfer protein | NA |
| UHGV-1410916_40 | eggNOG-mapper | 1236504.HMPREF2132_01885 | DNA restriction-modification system | NA |
| UHGV-1410916_40 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-1410916_40 | Structural annotation | PF19587, MF_01872, NF011489, COG0286 | NA | NA |
| UHGV-1410916_41 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1410916_41 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1410916_41 | UniRef90 | UniRef90_A0A2L2WN54 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1410916_41 | eggNOG-mapper | 762982.HMPREF9442_01221 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-1410916_41 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1410916_41 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1410916_41 | Structural annotation | PF01507, MF_00064, NF010367, COG0175 | NA | NA |
| UHGV-1410916_43 | UniRef90 | UniRef90_UPI001C2BD57F | phage holin family protein | NA |
| UHGV-1410916_43 | eggNOG-mapper | 457424.BFAG_02443 | NA | NA |
| UHGV-1410916_43 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-1410916_43 | Structural annotation | TIGR01593 | NA | NA |
| UHGV-1410916_44 | Structural annotation | PF20765 | NA | NA |
| UHGV-1410916_46 | KOfam | K20282 | GCC2; GRIP and coiled-coil domain-containing protein 2 | NA |
| UHGV-1410916_46 | PHROG | phrog_28 | tail length tape measure protein | tail |
| UHGV-1410916_46 | UniRef90 | UniRef90_A0A2L2WS53 | PhageMin_Tail domain-containing protein | NA |
| UHGV-1410916_46 | eggNOG-mapper | 1236504.HMPREF2132_01670 | tail tape measure protein, TP901 family | NA |
| UHGV-1410916_46 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-1410916_46 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1410916_46 | Structural annotation | PF10145, TIGR01760 | NA | NA |
| UHGV-1410916_49 | UniRef90 | UniRef90_A0A2L2WND9 | Primase C terminal 2 | NA |
| UHGV-1410916_49 | eggNOG-mapper | 1236504.HMPREF2132_01765 | Primase C terminal 2 (PriCT-2) | NA |
| UHGV-1410916_49 | PADLOC | drt-cluster64 | DRT | DRT |
| UHGV-1410916_49 | Pfam | PF08800 | BT4734-like, N-terminal domain | BT4734-like_N |
| UHGV-1410916_49 | Pfam | PF08707 | Primase C terminal 2 (PriCT-2) | PriCT_2 |
| UHGV-1410916_49 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-1410916_49 | Structural annotation | PF08800, NF040562 | NA | NA |
| UHGV-1410916_50 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-1410916_50 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-1410916_50 | UniRef90 | UniRef90_UPI001F2B8C95 | NA | NA |
| UHGV-1410916_50 | eggNOG-mapper | 1121896.JMLU01000022_gene2030 | This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | NA |
| UHGV-1410916_50 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-1410916_50 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-1410916_50 | Structural annotation | PF00692, MF_00116, NF001862, COG0756 | NA | NA |
| UHGV-1410916_53 | Structural annotation | PF11550, COG5437 | NA | NA |
| UHGV-1410916_55 | KOfam | K21511 | GPC; capsid assembly protease [EC:3.4.21.-] | NA |
| UHGV-1410916_55 | PHROG | phrog_53 | head maturation protease | head and packaging |
| UHGV-1410916_55 | UniRef90 | UniRef90_A0A2L2WN07 | Signal peptide peptidase SppA, 36K type | NA |
| UHGV-1410916_55 | eggNOG-mapper | 1236504.HMPREF2132_01855 | serine-type peptidase activity | NA |
| UHGV-1410916_55 | Pfam | PF01343 | Peptidase family S49 | Peptidase_S49 |
| UHGV-1410916_55 | COG | COG0616 | Periplasmic serine protease, ClpP class | NA |
| UHGV-1410916_55 | Structural annotation | PF01343, MF_00444, TIGR00706, COG0616 | NA | NA |
| UHGV-1410916_56 | Structural annotation | PF05065, PF18998, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1410916_57 | Structural annotation | TIGR01603, COG5437 | NA | NA |
| UHGV-1410916_58 | KOfam | K09681 | gltC; LysR family transcriptional regulator, transcription activator of glutamate synthase operon | NA |
| UHGV-1410916_58 | PHROG | phrog_3736 | NA | unknown function |
| UHGV-1410916_58 | UniRef90 | UniRef90_A0A353E8E6 | HTH lysR-type domain-containing protein | NA |
| UHGV-1410916_58 | eggNOG-mapper | 1317122.ATO12_13660 | LysR substrate binding domain | NA |
| UHGV-1410916_58 | Pfam | PF00126 | Bacterial regulatory helix-turn-helix protein, lysR family | HTH_1 |
| UHGV-1410916_58 | Pfam | PF03466 | LysR substrate binding domain | LysR_substrate |
| UHGV-1410916_58 | COG | COG0583 | DNA-binding transcriptional regulator, LysR family | NA |
| UHGV-1410916_58 | Structural annotation | PF03466, PF00126, MF_01233, NF040786, COG0583 | NA | NA |
| UHGV-1410916_61 | Structural annotation | PF10628 | NA | NA |
| UHGV-1410916_65 | PHROG | phrog_874 | NA | unknown function |
| UHGV-1410916_65 | eggNOG-mapper | 762968.HMPREF9441_00541 | NA | NA |
| UHGV-1410916_65 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-1410916_66 | Structural annotation | PF10827 | NA | NA |
| UHGV-1410916_67 | KOfam | K14415 | RTCB, rtcB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] | NA |
| UHGV-1410916_67 | PHROG | phrog_1075 | tRNA splicing ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1410916_67 | UniRef90 | UniRef90_A0A413CCX6 | RNA-splicing ligase RtcB | NA |
| UHGV-1410916_67 | eggNOG-mapper | 1089548.KI783301_gene2001 | tRNA-splicing ligase RtcB | NA |
| UHGV-1410916_67 | Pfam | PF01139 | tRNA-splicing ligase RtcB | RtcB |
| UHGV-1410916_67 | COG | COG1690 | RNA-splicing ligase RtcB, repairs tRNA damage | NA |
| UHGV-1410916_67 | Structural annotation | PF01139, MF_03144, NF007153, COG1690 | NA | NA |
| UHGV-1410916_68 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-1410916_68 | UniRef90 | UniRef90_UPI001F45D98B | YopX family protein | NA |
| UHGV-1410916_68 | eggNOG-mapper | 445970.ALIPUT_01614 | YopX protein | NA |
| UHGV-1410916_68 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-1410916_68 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-1410916_71 | Structural annotation | COG5475 | NA | NA |
| UHGV-1410916_74 | PHROG | phrog_1383 | virion structural protein | head and packaging |
| UHGV-1410916_74 | UniRef90 | UniRef90_R6U473 | Gp142 | NA |
| UHGV-1410916_74 | eggNOG-mapper | 1327935.A0A060AD14_9CAUD | NA | NA |
| UHGV-1410916_74 | Structural annotation | COG1704 | NA | NA |
| UHGV-1410916_75 | PHROG | phrog_2087 | NA | unknown function |
| UHGV-1410916_75 | eggNOG-mapper | 1410653.JHVC01000005_gene2495 | NA | NA |
| UHGV-1410916_76 | Structural annotation | PF13619 | NA | NA |
| UHGV-1410916_77 | eggNOG-mapper | 1235803.C825_03414 | NA | NA |
| UHGV-1410916_77 | Structural annotation | PF05136, MF_04135, TIGR01540, COG5518 | NA | NA |
| UHGV-1410916_78 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1410916_78 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-1410916_78 | UniRef90 | UniRef90_A0A255TPS1 | Methyltransferase | NA |
| UHGV-1410916_78 | eggNOG-mapper | 483215.BACFIN_05771 | Belongs to the N(4) N(6)-methyltransferase family | NA |
| UHGV-1410916_78 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-1410916_78 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1410916_78 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1410916_78 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-1410916_79 | Pfam | PF20459 | NA | DUF6712 |
| UHGV-1410916_79 | Structural annotation | PF20459 | NA | NA |
| UHGV-1410916_84 | PHROG | phrog_17422 | NA | unknown function |
| UHGV-1410916_84 | eggNOG-mapper | 1392486.JIAF01000004_gene815 | NA | NA |
| UHGV-1410916_85 | PHROG | phrog_15037 | NA | unknown function |
| UHGV-1410916_85 | UniRef90 | UniRef90_A0A7U3RL93 | Holin (Fragment) | NA |
| UHGV-1410916_85 | eggNOG-mapper | 411476.BACOVA_03950 | NA | NA |
| UHGV-1410916_85 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-1410916_86 | PHROG | phrog_1501 | NA | unknown function |
| UHGV-1410916_86 | UniRef90 | UniRef90_R6EVM2 | NA | NA |
| UHGV-1410916_86 | eggNOG-mapper | 1121097.JCM15093_2704 | NA | NA |
| UHGV-1410916_86 | Pfam | PF18925 | NA | DUF5675 |
| UHGV-1410916_86 | Structural annotation | PF18925 | NA | NA |
| UHGV-1410916_87 | eggNOG-mapper | 762982.HMPREF9442_01199 | NA | NA |
| UHGV-1410916_89 | PHROG | phrog_17134 | NA | unknown function |
| UHGV-1410916_89 | Structural annotation | PF14545, COG3126 | NA | NA |
| UHGV-1410916_91 | KOfam | K00986 | ltrA; RNA-directed DNA polymerase [EC:2.7.7.49] | NA |
| UHGV-1410916_91 | PHROG | phrog_1423 | Reverse transcriptase | DNA, RNA and nucleotide metabolism |
| UHGV-1410916_91 | PADLOC | icity0040 | RT (reverse transcriptase) | CRISPR-CAS |
| UHGV-1410916_91 | Structural annotation | PF00078, MF_04065, TIGR04416, COG3344 | NA | NA |
| UHGV-1410916_92 | UniRef90 | UniRef90_UPI001C49131D | NA | NA |
| UHGV-1410916_92 | eggNOG-mapper | 411479.BACUNI_00733 | NA | NA |
| UHGV-1410916_92 | Pfam | PF14301 | NA | DUF4376 |
| UHGV-1410916_92 | Structural annotation | PF14301 | NA | NA |
| UHGV-1410916_93 | Structural annotation | PF11797, MF_00791, NF003967, COG2967 | NA | NA |
| UHGV-1410916_94 | UniRef90 | UniRef90_R6YPV7 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1410916_94 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1410916_95 | eggNOG-mapper | 926549.KI421517_gene2307 | NA | NA |