| UHGV-1434091_1 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1434091_1 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1434091_1 | UniRef90 | UniRef90_UPI001EE0856C | helix-turn-helix domain-containing protein | NA |
| UHGV-1434091_1 | eggNOG-mapper | 1256908.HMPREF0373_00219 | sequence-specific DNA binding | NA |
| UHGV-1434091_1 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1434091_1 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1434091_1 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1434091_1 | Structural annotation | PF12844, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1434091_2 | UniRef90 | UniRef90_UPI001EE0CE96 | helix-turn-helix domain-containing protein | NA |
| UHGV-1434091_2 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-1434091_8 | PHROG | phrog_30234 | NA | unknown function |
| UHGV-1434091_8 | eggNOG-mapper | 33035.JPJF01000071_gene4461 | NA | NA |
| UHGV-1434091_9 | PHROG | phrog_659 | Sak-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1434091_9 | UniRef90 | UniRef90_UPI0006D01DEB | NA | NA |
| UHGV-1434091_9 | eggNOG-mapper | 33035.JPJF01000135_gene5082 | NA | NA |
| UHGV-1434091_9 | Pfam | PF06378 | NA | DUF1071 |
| UHGV-1434091_9 | Structural annotation | PF06378, TIGR00607, COG5055 | NA | NA |
| UHGV-1434091_11 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-1434091_11 | eggNOG-mapper | 411468.CLOSCI_00314 | NA | NA |
| UHGV-1434091_11 | Structural annotation | PF05772, NF007281 | NA | NA |
| UHGV-1434091_12 | PHROG | phrog_2113 | NA | unknown function |
| UHGV-1434091_12 | UniRef90 | UniRef90_A0A357NGS2 | HTH_11 domain-containing protein | NA |
| UHGV-1434091_12 | eggNOG-mapper | 365659.smi_2008 | NA | NA |
| UHGV-1434091_13 | PHROG | phrog_244 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1434091_13 | eggNOG-mapper | 33035.JPJF01000122_gene2460 | NA | NA |
| UHGV-1434091_13 | Structural annotation | PF01870, MF_01490, NF040854, COG1591 | NA | NA |
| UHGV-1434091_14 | PHROG | phrog_2514 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-1434091_14 | UniRef90 | UniRef90_A0A174WT25 | Replication initiator A domain-containing protein | NA |
| UHGV-1434091_14 | eggNOG-mapper | 742733.HMPREF9469_01845 | NA | NA |
| UHGV-1434091_14 | Structural annotation | PF10771, MF_01177, TIGR01714, COG0640 | NA | NA |
| UHGV-1434091_16 | UniRef90 | UniRef90_A0A373MX33 | NA | NA |
| UHGV-1434091_16 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1434091_16 | Structural annotation | PF04448, NF041588 | NA | NA |
| UHGV-1434091_17 | PHROG | phrog_7488 | NA | unknown function |
| UHGV-1434091_19 | Structural annotation | PF16467 | NA | NA |
| UHGV-1434091_20 | PHROG | phrog_15077 | NA | unknown function |
| UHGV-1434091_20 | eggNOG-mapper | 742740.HMPREF9474_03494 | NA | NA |
| UHGV-1434091_22 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1434091_22 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1434091_22 | UniRef90 | UniRef90_UPI0018A95D39 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-1434091_22 | eggNOG-mapper | 742765.HMPREF9457_03403 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-1434091_22 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1434091_22 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1434091_22 | Structural annotation | PF01507, MF_00063, NF006327, COG0175 | NA | NA |
| UHGV-1434091_23 | KOfam | K07319 | yhdJ; adenine-specific DNA-methyltransferase [EC:2.1.1.72] | NA |
| UHGV-1434091_23 | PHROG | phrog_23224 | DNA methyltransferase | other |
| UHGV-1434091_23 | UniRef90 | UniRef90_A0A396PTY1 | Methyltransferase | NA |
| UHGV-1434091_23 | eggNOG-mapper | 1214217.ALNF01000014_gene1390 | N-4 methylation of cytosine | NA |
| UHGV-1434091_23 | PADLOC | MTase_II_00172 | Type II methyltransferase | RM |
| UHGV-1434091_23 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1434091_23 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1434091_23 | Structural annotation | PF01555, NF010253, COG0863 | NA | NA |
| UHGV-1434091_24 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1434091_24 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1434091_24 | UniRef90 | UniRef90_C0BC27 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1434091_24 | eggNOG-mapper | 1499683.CCFF01000017_gene2594 | PFAM C-5 cytosine-specific DNA methylase | NA |
| UHGV-1434091_24 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-1434091_24 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1434091_24 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1434091_24 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1434091_24 | Structural annotation | PF00145, MF_00786, TIGR00675, COG0270 | NA | NA |
| UHGV-1434091_29 | PHROG | phrog_9822 | NA | unknown function |
| UHGV-1434091_30 | eggNOG-mapper | 887325.HMPREF0381_0090 | NA | NA |
| UHGV-1434091_31 | UniRef90 | UniRef90_A0A373MXP0 | NA | NA |
| UHGV-1434091_32 | eggNOG-mapper | 397290.C810_01505 | NA | NA |
| UHGV-1434091_33 | PHROG | phrog_20593 | NA | unknown function |
| UHGV-1434091_33 | UniRef90 | UniRef90_UPI001C00E342 | NA | NA |
| UHGV-1434091_34 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-1434091_34 | UniRef90 | UniRef90_A0A373MXN9 | YopX domain-containing protein | NA |
| UHGV-1434091_34 | eggNOG-mapper | 457412.RSAG_01162 | YopX protein | NA |
| UHGV-1434091_34 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-1434091_34 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-1434091_35 | UniRef90 | UniRef90_UPI000CF8F0F1 | NA | NA |
| UHGV-1434091_35 | eggNOG-mapper | 97139.C824_02654 | NA | NA |
| UHGV-1434091_35 | Pfam | PF07866 | NA | DUF1653 |
| UHGV-1434091_35 | COG | COG4728 | NA | NA |
| UHGV-1434091_35 | Structural annotation | PF07866, COG4728 | NA | NA |
| UHGV-1434091_37 | eggNOG-mapper | 476272.RUMHYD_01751 | NA | NA |
| UHGV-1434091_38 | PHROG | phrog_8680 | NA | unknown function |
| UHGV-1434091_38 | UniRef90 | UniRef90_A0A373MX42 | NA | NA |
| UHGV-1434091_38 | eggNOG-mapper | 411470.RUMGNA_02208 | NA | NA |
| UHGV-1434091_38 | Pfam | PF14386 | NA | DUF4417 |
| UHGV-1434091_38 | Structural annotation | PF14386 | NA | NA |
| UHGV-1434091_40 | PHROG | phrog_9479 | NA | unknown function |
| UHGV-1434091_41 | PHROG | phrog_33130 | NA | unknown function |
| UHGV-1434091_41 | Structural annotation | PF10922, MF_00839 | NA | NA |
| UHGV-1434091_43 | KOfam | K07474 | xtmA; phage terminase small subunit | NA |
| UHGV-1434091_43 | PHROG | phrog_51 | terminase small subunit | head and packaging |
| UHGV-1434091_43 | UniRef90 | UniRef90_A0A373MWB9 | Terminase small subunit | NA |
| UHGV-1434091_43 | eggNOG-mapper | 1235800.C819_00494 | Terminase small subunit | NA |
| UHGV-1434091_43 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-1434091_43 | COG | COG3728 | Phage terminase, small subunit | NA |
| UHGV-1434091_43 | Structural annotation | PF03592, COG3728 | NA | NA |
| UHGV-1434091_44 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-1434091_44 | PHROG | phrog_10250 | NA | unknown function |
| UHGV-1434091_44 | UniRef90 | UniRef90_A0A373MY72 | PBSX family phage terminase large subunit | NA |
| UHGV-1434091_44 | eggNOG-mapper | 397290.C810_05187 | Phage terminase large subunit | NA |
| UHGV-1434091_44 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-1434091_44 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-1434091_44 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-1434091_44 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-1434091_46 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-1434091_46 | UniRef90 | UniRef90_A0A173R9C0 | Phage portal protein, putative, A118 family | NA |
| UHGV-1434091_46 | eggNOG-mapper | 476272.RUMHYD_01758 | phage minor capsid protein | NA |
| UHGV-1434091_46 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-1434091_47 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-1434091_47 | UniRef90 | UniRef90_A0A373MX10 | NA | NA |
| UHGV-1434091_47 | eggNOG-mapper | 457412.RSAG_01107 | NA | NA |
| UHGV-1434091_47 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-1434091_47 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-1434091_47 | Structural annotation | PF11195 | NA | NA |
| UHGV-1434091_49 | PHROG | phrog_2428 | NA | unknown function |
| UHGV-1434091_49 | UniRef90 | UniRef90_A0A396QA65 | ABC transporter ATPase | NA |
| UHGV-1434091_49 | eggNOG-mapper | 632245.CLP_1645 | NA | NA |
| UHGV-1434091_49 | dbAPIS | APIS024 | Tad1 proteins are not an enzymes, but are 'sponges' that bind and sequester the immune signaling molecule (cyclic ADP-ribose or gcADPR) produced by TIR-domain proteins, thus decoupling phage sensing from immune effector activation and rendering Thoeris inactive. | NA |
| UHGV-1434091_50 | KOfam | K03744 | lemA; LemA protein | NA |
| UHGV-1434091_50 | PHROG | phrog_1383 | virion structural protein | head and packaging |
| UHGV-1434091_50 | UniRef90 | UniRef90_A0A893W810 | LemA family protein | NA |
| UHGV-1434091_50 | eggNOG-mapper | 742735.HMPREF9467_00879 | LemA family | NA |
| UHGV-1434091_50 | Pfam | PF04011 | LemA family | LemA |
| UHGV-1434091_50 | COG | COG1704 | Magnetosome formation protein MamQ, lipoprotein antigen LemA family | NA |
| UHGV-1434091_50 | Structural annotation | PF04011, NF040966, COG1704 | NA | NA |
| UHGV-1434091_51 | PHROG | phrog_3886 | NA | unknown function |
| UHGV-1434091_51 | eggNOG-mapper | 742740.HMPREF9474_02292 | NA | NA |
| UHGV-1434091_53 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-1434091_53 | UniRef90 | UniRef90_A0A373MXM0 | Phage capsid protein | NA |
| UHGV-1434091_53 | eggNOG-mapper | 476272.RUMHYD_01761 | Phage minor capsid protein 2 | NA |
| UHGV-1434091_53 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-1434091_53 | COG | COG2369 | NA | NA |
| UHGV-1434091_53 | Structural annotation | PF06152 | NA | NA |
| UHGV-1434091_54 | PHROG | phrog_194 | head scaffolding protein | head and packaging |
| UHGV-1434091_54 | UniRef90 | UniRef90_R6NCU4 | Putative scaffolding protein | NA |
| UHGV-1434091_54 | eggNOG-mapper | 397290.C810_05223 | Phage minor structural protein GP20 | NA |
| UHGV-1434091_54 | Pfam | PF06810 | Phage minor structural protein GP20 | Phage_GP20 |
| UHGV-1434091_54 | Structural annotation | PF06810 | NA | NA |
| UHGV-1434091_55 | UniRef90 | UniRef90_A0A0M2NI16 | S-l_SbsC_C domain-containing protein | NA |
| UHGV-1434091_55 | Structural annotation | PF11651, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-1434091_57 | PHROG | phrog_541 | head-tail adaptor | connector |
| UHGV-1434091_57 | eggNOG-mapper | 476272.RUMHYD_01778 | NA | NA |
| UHGV-1434091_59 | PHROG | phrog_3366 | NA | unknown function |
| UHGV-1434091_59 | eggNOG-mapper | 476272.RUMHYD_01779 | NA | NA |
| UHGV-1434091_59 | Structural annotation | PF20536, COG5614 | NA | NA |
| UHGV-1434091_60 | PHROG | phrog_556 | minor head protein | head and packaging |
| UHGV-1434091_60 | UniRef90 | UniRef90_UPI0008B4CFF0 | minor capsid protein | NA |
| UHGV-1434091_60 | eggNOG-mapper | 476272.RUMHYD_01780 | NA | NA |
| UHGV-1434091_60 | Pfam | PF11114 | Minor capsid protein | Minor_capsid_2 |
| UHGV-1434091_60 | Structural annotation | PF11114 | NA | NA |
| UHGV-1434091_61 | PHROG | phrog_3266 | tail completion | connector |
| UHGV-1434091_61 | eggNOG-mapper | 476272.RUMHYD_01781 | NA | NA |
| UHGV-1434091_61 | Structural annotation | PF12691 | NA | NA |
| UHGV-1434091_62 | PHROG | phrog_3099 | NA | unknown function |
| UHGV-1434091_62 | eggNOG-mapper | 476272.RUMHYD_01782 | NA | NA |
| UHGV-1434091_62 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-1434091_63 | PHROG | phrog_11299 | NA | unknown function |
| UHGV-1434091_63 | eggNOG-mapper | 33035.JPJF01000106_gene3125 | NA | NA |
| UHGV-1434091_63 | Structural annotation | PF10666 | NA | NA |
| UHGV-1434091_64 | PHROG | phrog_706 | NA | unknown function |
| UHGV-1434091_64 | UniRef90 | UniRef90_UPI00156F9D1C | Gp15 family bacteriophage protein | NA |
| UHGV-1434091_64 | eggNOG-mapper | 411459.RUMOBE_01383 | Bacteriophage Gp15 protein | NA |
| UHGV-1434091_64 | Pfam | PF06854 | Bacteriophage Gp15 protein | Phage_Gp15 |
| UHGV-1434091_64 | Structural annotation | PF06854 | NA | NA |
| UHGV-1434091_65 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-1434091_65 | UniRef90 | UniRef90_A0A173R880 | Phage-related protein | NA |
| UHGV-1434091_65 | eggNOG-mapper | 476272.RUMHYD_01785 | phage tail tape measure protein | NA |
| UHGV-1434091_65 | COG | COG1511 | NA | NA |
| UHGV-1434091_66 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-1434091_66 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-1434091_67 | PHROG | phrog_6616 | tail protein | tail |
| UHGV-1434091_67 | UniRef90 | UniRef90_UPI0015714EA8 | tail fiber domain-containing protein | NA |
| UHGV-1434091_67 | eggNOG-mapper | 357276.EL88_12830 | Phage minor structural protein | NA |
| UHGV-1434091_67 | COG | COG4926 | Phage-related protein | NA |
| UHGV-1434091_67 | Structural annotation | PF05113, NF033848, COG3500 | NA | NA |
| UHGV-1434091_69 | eggNOG-mapper | 411471.SUBVAR_06976 | NA | NA |