| UHGV-1454182_2 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-1454182_2 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_2 | UniRef90 | UniRef90_UPI001898977C | FAD-dependent thymidylate synthase | NA |
| UHGV-1454182_2 | eggNOG-mapper | 1336241.JAEB01000001_gene147 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant | NA |
| UHGV-1454182_2 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-1454182_2 | NCBIFam | TIGR02170.1 | FAD-dependent thymidylate synthase | NA |
| UHGV-1454182_2 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-1454182_2 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-1454182_3 | KOfam | K03698 | cbf, cbf1; 3'-5' exoribonuclease [EC:3.1.-.-] | NA |
| UHGV-1454182_3 | PHROG | phrog_28876 | metal-dependent phosphohydrolase | other |
| UHGV-1454182_3 | UniRef90 | UniRef90_A0A1C5MUY3 | Predicted HD-superfamily hydrolase | NA |
| UHGV-1454182_3 | eggNOG-mapper | 1235800.C819_00499 | metal-dependent phosphohydrolase, HD sub domain | NA |
| UHGV-1454182_3 | COG | COG3481 | 3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation, HD superfamily | NA |
| UHGV-1454182_3 | Structural annotation | PF01966, MF_01427, NF010007, COG3481 | NA | NA |
| UHGV-1454182_4 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-1454182_4 | UniRef90 | UniRef90_UPI001899D94E | nucleoside triphosphate pyrophosphohydrolase family protein | NA |
| UHGV-1454182_4 | eggNOG-mapper | 428125.CLOLEP_01391 | MazG nucleotide pyrophosphohydrolase domain | NA |
| UHGV-1454182_4 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-1454182_4 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-1454182_4 | Structural annotation | PF03819, MF_01020, NF001613, COG0140 | NA | NA |
| UHGV-1454182_5 | Structural annotation | PF08410, COG5515 | NA | NA |
| UHGV-1454182_6 | PHROG | phrog_1485 | NA | unknown function |
| UHGV-1454182_6 | UniRef90 | UniRef90_H1CES0 | NA | NA |
| UHGV-1454182_6 | eggNOG-mapper | 1415774.U728_1099 | NA | NA |
| UHGV-1454182_6 | Pfam | PF07659 | Nucleotide modification associated domain 1 | DUF1599 |
| UHGV-1454182_7 | Structural annotation | PF05037, NF005674 | NA | NA |
| UHGV-1454182_9 | AcrCatalog | cluster_73853 | NA | NA |
| UHGV-1454182_10 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_10 | UniRef90 | UniRef90_H1CES3 | YqaJ domain-containing protein | NA |
| UHGV-1454182_10 | eggNOG-mapper | 1121866.AUGK01000003_gene1405 | YqaJ viral recombinase family | NA |
| UHGV-1454182_10 | Pfam | PF09588 | YqaJ-like viral recombinase domain | YqaJ |
| UHGV-1454182_10 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-1454182_10 | Structural annotation | PF09588, TIGR03033, COG5377 | NA | NA |
| UHGV-1454182_11 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_11 | UniRef90 | UniRef90_UPI001A9A8367 | ERF family protein | NA |
| UHGV-1454182_11 | eggNOG-mapper | 936572.HMPREF1148_0677 | ERF superfamily | NA |
| UHGV-1454182_11 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-1454182_11 | Structural annotation | PF04404 | NA | NA |
| UHGV-1454182_13 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-1454182_13 | UniRef90 | UniRef90_A0A349Q001 | Conjugal transfer protein | NA |
| UHGV-1454182_13 | eggNOG-mapper | 1123263.AUKY01000096_gene1823 | DNA restriction-modification system | NA |
| UHGV-1454182_13 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-1454182_13 | Structural annotation | PF19587, MF_01872, NF011489, COG0286 | NA | NA |
| UHGV-1454182_14 | PHROG | phrog_1252 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_14 | UniRef90 | UniRef90_UPI00189DB5D1 | DNA polymerase elongation subunit (family B) | NA |
| UHGV-1454182_14 | eggNOG-mapper | 1121866.AUGK01000003_gene1403 | DNA replication proofreading | NA |
| UHGV-1454182_14 | COG | COG0417 | DNA polymerase B elongation subunit | NA |
| UHGV-1454182_14 | Structural annotation | PF08490, MF_04100, TIGR00592, COG0417 | NA | NA |
| UHGV-1454182_16 | PHROG | phrog_757 | DNA methyltransferase | other |
| UHGV-1454182_16 | UniRef90 | UniRef90_UPI00189BA758 | DNA cytosine methyltransferase | NA |
| UHGV-1454182_16 | eggNOG-mapper | 742733.HMPREF9469_01835 | DNA (cytosine-5-)-methyltransferase activity | NA |
| UHGV-1454182_16 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1454182_16 | Structural annotation | PF00145, MF_01872, TIGR00675, COG0270 | NA | NA |
| UHGV-1454182_17 | KOfam | K18959 | uvsW; ATP-dependent DNA helicase UvsW [EC:5.6.2.4] | NA |
| UHGV-1454182_17 | PHROG | phrog_16 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_17 | UniRef90 | UniRef90_H1CET1 | Helicase ATP-binding domain-containing protein | NA |
| UHGV-1454182_17 | eggNOG-mapper | 1232453.BAIF02000010_gene3343 | Type III restriction protein res subunit | NA |
| UHGV-1454182_17 | PADLOC | mREase_IV_00004 | Type IV methyl-directed restriction enzyme | RM |
| UHGV-1454182_17 | Pfam | PF04851 | Type III restriction enzyme, res subunit | ResIII |
| UHGV-1454182_17 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-1454182_17 | COG | COG1061 | Superfamily II DNA or RNA helicase | NA |
| UHGV-1454182_17 | Structural annotation | PF04851, PF16203, MF_01489, TIGR00603, COG1061 | NA | NA |
| UHGV-1454182_18 | PHROG | phrog_843 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_18 | UniRef90 | UniRef90_UPI0018982E6D | Holliday junction resolvase RecU | NA |
| UHGV-1454182_18 | eggNOG-mapper | 1449050.JNLE01000003_gene3909 | Recombination protein U | NA |
| UHGV-1454182_18 | Structural annotation | PF03838, MF_01490, NF002581, COG1591 | NA | NA |
| UHGV-1454182_20 | PHROG | phrog_37900 | NA | unknown function |
| UHGV-1454182_20 | UniRef90 | UniRef90_H1CET4 | NA | NA |
| UHGV-1454182_20 | eggNOG-mapper | 1121866.AUGK01000004_gene188 | serine threonine protein kinase | NA |
| UHGV-1454182_20 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-1454182_20 | COG | COG3827 | Cell pole-organizing protein PopZ | NA |
| UHGV-1454182_20 | Structural annotation | PF19789 | NA | NA |
| UHGV-1454182_22 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1454182_22 | UniRef90 | UniRef90_UPI00189B6D19 | helix-turn-helix domain-containing protein | NA |
| UHGV-1454182_22 | eggNOG-mapper | 97138.C820_00203 | Transcriptional | NA |
| UHGV-1454182_22 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1454182_22 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1454182_23 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-1454182_23 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-1454182_23 | UniRef90 | UniRef90_UPI00164E9A6A | recombinase family protein | NA |
| UHGV-1454182_23 | eggNOG-mapper | 663278.Ethha_0939 | NA | NA |
| UHGV-1454182_23 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-1454182_23 | Pfam | PF07508 | Recombinase | Recombinase |
| UHGV-1454182_23 | Pfam | PF13408 | Recombinase zinc beta ribbon domain | Zn_ribbon_recom |
| UHGV-1454182_23 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-1454182_23 | Structural annotation | PF07508, PF00239, NF041201, COG1961 | NA | NA |
| UHGV-1454182_26 | UniRef90 | UniRef90_H1CEM5 | SH3b domain-containing protein | NA |
| UHGV-1454182_26 | eggNOG-mapper | 1235797.C816_02842 | mannosyl-glycoprotein | NA |
| UHGV-1454182_26 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-1454182_26 | COG | COG0791 | Cell wall-associated hydrolase, NlpC_P60 family | NA |
| UHGV-1454182_26 | Structural annotation | PF05382, NF033743 | NA | NA |
| UHGV-1454182_27 | PHROG | phrog_13256 | NA | unknown function |
| UHGV-1454182_27 | eggNOG-mapper | 1226322.HMPREF1545_00166 | NA | NA |
| UHGV-1454182_28 | PHROG | phrog_1863 | NA | unknown function |
| UHGV-1454182_28 | eggNOG-mapper | 748224.HMPREF9436_00408 | NA | NA |
| UHGV-1454182_29 | eggNOG-mapper | 1235797.C816_04174 | NA | NA |
| UHGV-1454182_29 | Structural annotation | PF14600 | NA | NA |
| UHGV-1454182_30 | KOfam | K00986 | ltrA; RNA-directed DNA polymerase [EC:2.7.7.49] | NA |
| UHGV-1454182_30 | PHROG | phrog_1423 | Reverse transcriptase | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_30 | UniRef90 | UniRef90_H1CEN0 | Reverse transcriptase domain-containing protein | NA |
| UHGV-1454182_30 | eggNOG-mapper | 521003.COLINT_02359 | Reverse transcriptase (RNA-dependent DNA polymerase) | NA |
| UHGV-1454182_30 | PADLOC | icity0040 | RT (reverse transcriptase) | CRISPR-CAS |
| UHGV-1454182_30 | Pfam | PF00078 | Reverse transcriptase (RNA-dependent DNA polymerase) | RVT_1 |
| UHGV-1454182_30 | COG | COG3344 | Retron-type reverse transcriptase | NA |
| UHGV-1454182_30 | Structural annotation | PF00078, MF_01390, TIGR04416, COG3344 | NA | NA |
| UHGV-1454182_31 | PHROG | phrog_30516 | NA | unknown function |
| UHGV-1454182_31 | Structural annotation | PF05635, NF008911 | NA | NA |
| UHGV-1454182_32 | PHROG | phrog_37900 | NA | unknown function |
| UHGV-1454182_32 | UniRef90 | UniRef90_H1CEN2 | NA | NA |
| UHGV-1454182_32 | eggNOG-mapper | 1519439.JPJG01000060_gene1894 | NA | NA |
| UHGV-1454182_32 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-1454182_32 | COG | COG3827 | Cell pole-organizing protein PopZ | NA |
| UHGV-1454182_32 | Structural annotation | PF19789, PF14686, TIGR04183, COG2512 | NA | NA |
| UHGV-1454182_33 | PHROG | phrog_18725 | NA | unknown function |
| UHGV-1454182_33 | eggNOG-mapper | 1226322.HMPREF1545_00062 | NA | NA |
| UHGV-1454182_34 | PHROG | phrog_13879 | NA | unknown function |
| UHGV-1454182_34 | eggNOG-mapper | 665956.HMPREF1032_03630 | NA | NA |
| UHGV-1454182_34 | Structural annotation | PF03256, PF16466, PF13550, MF_00813, NF033848, COG3500 | NA | NA |
| UHGV-1454182_35 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-1454182_35 | eggNOG-mapper | 742740.HMPREF9474_03515 | NA | NA |
| UHGV-1454182_35 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-1454182_36 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-1454182_36 | eggNOG-mapper | 428127.EUBDOL_01563 | homoserine transmembrane transporter activity | NA |
| UHGV-1454182_36 | COG | COG1280 | Threonine/homoserine/homoserine lactone efflux protein | NA |
| UHGV-1454182_37 | eggNOG-mapper | 1121333.JMLH01000047_gene1011 | NA | NA |
| UHGV-1454182_38 | UniRef90 | UniRef90_UPI0018999178 | NA | NA |
| UHGV-1454182_38 | eggNOG-mapper | 1123263.AUKY01000015_gene1618 | NA | NA |
| UHGV-1454182_38 | Pfam | PF16478 | NA | DUF5055 |
| UHGV-1454182_38 | Structural annotation | PF16478 | NA | NA |
| UHGV-1454182_39 | PHROG | phrog_158 | major tail protein | tail |
| UHGV-1454182_39 | UniRef90 | UniRef90_UPI00164D954A | phage tail protein | NA |
| UHGV-1454182_39 | eggNOG-mapper | 1232453.BAIF02000058_gene1634 | NA | NA |
| UHGV-1454182_39 | Structural annotation | PF16463, TIGR02241, COG5437 | NA | NA |
| UHGV-1454182_40 | Structural annotation | PF06141, TIGR02367, COG3167 | NA | NA |
| UHGV-1454182_41 | eggNOG-mapper | 1298920.KI911353_gene2654 | NA | NA |
| UHGV-1454182_42 | eggNOG-mapper | 1298920.KI911353_gene2656 | NA | NA |
| UHGV-1454182_43 | UniRef90 | UniRef90_UPI001898B4B4 | phage head-tail connector protein | NA |
| UHGV-1454182_43 | eggNOG-mapper | 1298920.KI911353_gene2658 | NA | NA |
| UHGV-1454182_43 | Pfam | PF05135 | Phage gp6-like head-tail connector protein | Phage_connect_1 |
| UHGV-1454182_43 | Structural annotation | TIGR01560 | NA | NA |
| UHGV-1454182_44 | PHROG | phrog_1328 | major head protein | head and packaging |
| UHGV-1454182_44 | UniRef90 | UniRef90_UPI00164DD2D5 | NA | NA |
| UHGV-1454182_44 | eggNOG-mapper | 665956.HMPREF1032_03619 | NA | NA |
| UHGV-1454182_44 | Pfam | PF17236 | NA | DUF5309 |
| UHGV-1454182_44 | Structural annotation | PF17236, MF_04119, NF041162, COG4653 | NA | NA |
| UHGV-1454182_47 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-1454182_47 | UniRef90 | UniRef90_A0A6I2QXE1 | Phage portal protein | NA |
| UHGV-1454182_47 | eggNOG-mapper | 1123263.AUKY01000015_gene1609 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1454182_47 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-1454182_47 | Structural annotation | PF05133, MF_04120, TIGR01538, COG5511 | NA | NA |
| UHGV-1454182_48 | PHROG | phrog_38 | terminase large subunit | head and packaging |
| UHGV-1454182_48 | UniRef90 | UniRef90_A0A6I2QXZ5 | Phage terminase large subunit | NA |
| UHGV-1454182_48 | eggNOG-mapper | 1298920.KI911353_gene2682 | TIGRFAM Phage | NA |
| UHGV-1454182_48 | NCBIFam | TIGR01630.1 | phage terminase large subunit | NA |
| UHGV-1454182_48 | COG | COG5410 | NA | NA |
| UHGV-1454182_48 | Structural annotation | PF17289, PF02562, MF_04147, NF033889, COG5362, COG5410 | NA | NA |
| UHGV-1454182_50 | KOfam | K14060 | pinR; putative DNA-invertase from lambdoid prophage Rac | NA |
| UHGV-1454182_50 | PHROG | phrog_125 | DNA invertase | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_50 | UniRef90 | UniRef90_H1CEQ0 | Resolvase/invertase-type recombinase catalytic domain-containing protein | NA |
| UHGV-1454182_50 | eggNOG-mapper | 1294142.CINTURNW_1680 | Resolvase, N terminal domain | NA |
| UHGV-1454182_50 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-1454182_50 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-1454182_50 | Structural annotation | PF00239, NF009949, COG1961 | NA | NA |
| UHGV-1454182_51 | UniRef90 | UniRef90_UPI001D08C4A6 | helix-turn-helix domain-containing protein | NA |
| UHGV-1454182_51 | Structural annotation | PF20075, TIGR03070 | NA | NA |
| UHGV-1454182_52 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_52 | eggNOG-mapper | 1378168.N510_00538 | NA | NA |
| UHGV-1454182_57 | PHROG | phrog_606 | terminase small subunit | head and packaging |
| UHGV-1454182_57 | UniRef90 | UniRef90_UPI001D08D6B6 | DNA-packaging protein | NA |
| UHGV-1454182_57 | eggNOG-mapper | 1235793.C809_00539 | NA | NA |
| UHGV-1454182_57 | Pfam | PF16677 | DNA-packaging protein gp3 | GP3_package |
| UHGV-1454182_57 | Structural annotation | PF16677 | NA | NA |
| UHGV-1454182_59 | NCBIFam | TIGR03831.1 | YgiT-type zinc finger protein | NA |
| UHGV-1454182_62 | PHROG | phrog_22389 | NA | unknown function |
| UHGV-1454182_62 | Structural annotation | PF01402, COG4710 | NA | NA |
| UHGV-1454182_63 | PHROG | phrog_1156 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_63 | UniRef90 | UniRef90_H1CER1 | Phage/plasmid primase, P4 family domain-containing protein | NA |
| UHGV-1454182_63 | eggNOG-mapper | 649747.HMPREF0083_00553 | Phage plasmid primase, P4 family | NA |
| UHGV-1454182_63 | Pfam | PF08706 | D5 N terminal like | D5_N |
| UHGV-1454182_63 | Pfam | PF19263 | NA | DUF5906 |
| UHGV-1454182_63 | Pfam | PF03288 | Poxvirus D5 protein-like | Pox_D5 |
| UHGV-1454182_63 | NCBIFam | TIGR01613.1 | phage/plasmid primase, P4 family | NA |
| UHGV-1454182_63 | COG | COG3378 | DNA primase, phage- or plasmid-associated | NA |
| UHGV-1454182_63 | Structural annotation | PF08706, PF05272, PF02257, MF_04000, NF005477, COG3378 | NA | NA |
| UHGV-1454182_65 | KOfam | K07171 | mazF, ndoA, chpA; mRNA interferase MazF [EC:3.1.-.-] | NA |
| UHGV-1454182_65 | PHROG | phrog_1936 | MazF-like growth inhibitor | moron, auxiliary metabolic gene and host takeover |
| UHGV-1454182_65 | UniRef90 | UniRef90_UPI001D0750B0 | type II toxin-antitoxin system PemK/MazF family toxin | NA |
| UHGV-1454182_65 | eggNOG-mapper | 553973.CLOHYLEM_03974 | Toxic component of a toxin-antitoxin (TA) module | NA |
| UHGV-1454182_65 | Pfam | PF02452 | PemK-like, MazF-like toxin of type II toxin-antitoxin system | PemK_toxin |
| UHGV-1454182_65 | COG | COG2337 | mRNA-degrading endonuclease MazF, toxin component of the MazEF toxin-antitoxin module | NA |
| UHGV-1454182_65 | Structural annotation | PF02452, NF007386, COG2337 | NA | NA |
| UHGV-1454182_66 | PHROG | phrog_1829 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1454182_66 | UniRef90 | UniRef90_H1CER3 | PriCT_1 domain-containing protein | NA |
| UHGV-1454182_66 | eggNOG-mapper | 1121866.AUGK01000003_gene1409 | Phage plasmid primase, P4 family domain protein | NA |
| UHGV-1454182_66 | Pfam | PF08708 | Primase C terminal 1 (PriCT-1) | PriCT_1 |
| UHGV-1454182_66 | COG | COG4983 | Primase-polymerase (Primpol) domain protein | NA |
| UHGV-1454182_66 | Structural annotation | PF08708, PF09250, COG4983 | NA | NA |
| UHGV-1454182_67 | PHROG | phrog_30550 | NA | unknown function |
| UHGV-1454182_67 | UniRef90 | UniRef90_A0A6N9PX25 | Cell wall hydrolase | NA |
| UHGV-1454182_67 | eggNOG-mapper | 1519439.JPJG01000077_gene920 | Cell Wall Hydrolase | NA |
| UHGV-1454182_67 | Structural annotation | TIGR02869 | NA | NA |