| UHGV-1472693_3 | UniRef90 | UniRef90_A0A7J0A8P0 | HTH-type transcriptional regulator SinR | NA |
| UHGV-1472693_3 | eggNOG-mapper | 1268240.ATFI01000020_gene152 | NA | NA |
| UHGV-1472693_3 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1472693_3 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1472693_3 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1472693_4 | UniRef90 | UniRef90_A0A2D3LPV5 | Pilus assembly protein HicB | NA |
| UHGV-1472693_4 | eggNOG-mapper | 264731.PRU_1050 | PFAM Uncharacterised protein family UPF0150 | NA |
| UHGV-1472693_4 | COG | COG1598 | Antitoxin component HicB of the HicAB toxin-antitoxin system | NA |
| UHGV-1472693_4 | Structural annotation | PF21748, NF041951, COG1598 | NA | NA |
| UHGV-1472693_5 | KOfam | K07339 | hicA; mRNA interferase HicA [EC:3.1.-.-] | NA |
| UHGV-1472693_5 | UniRef90 | UniRef90_R7H4B3 | Toxin-antitoxin system toxin component HicA family | NA |
| UHGV-1472693_5 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-1472693_5 | COG | COG1724 | Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family | NA |
| UHGV-1472693_5 | Structural annotation | PF07927, COG1724 | NA | NA |
| UHGV-1472693_6 | eggNOG-mapper | 585543.HMPREF0969_03349 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-1472693_6 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1472693_6 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1472693_9 | PHROG | phrog_1501 | NA | unknown function |
| UHGV-1472693_9 | UniRef90 | UniRef90_R6EVM2 | NA | NA |
| UHGV-1472693_9 | eggNOG-mapper | 679935.Alfi_0537 | NA | NA |
| UHGV-1472693_9 | Pfam | PF18925 | NA | DUF5675 |
| UHGV-1472693_9 | Structural annotation | PF18925 | NA | NA |
| UHGV-1472693_11 | KOfam | K10268 | FBXL2_20; F-box and leucine-rich repeat protein 2/20 | NA |
| UHGV-1472693_11 | PHROG | phrog_17273 | NA | unknown function |
| UHGV-1472693_11 | UniRef90 | UniRef90_UPI001F431ADA | BspA family leucine-rich repeat surface protein | NA |
| UHGV-1472693_11 | Pfam | PF03382 | NA | DUF285 |
| UHGV-1472693_11 | NCBIFam | TIGR02167.1 | bacterial surface protein 26-residue repeat | NA |
| UHGV-1472693_12 | Structural annotation | PF21146, NF033814 | NA | NA |
| UHGV-1472693_13 | PHROG | phrog_38044 | NA | unknown function |
| UHGV-1472693_13 | eggNOG-mapper | 762982.HMPREF9442_01191 | cellulase activity | NA |
| UHGV-1472693_13 | Pfam | PF02018 | Carbohydrate binding domain | CBM_4_9 |
| UHGV-1472693_13 | COG | COG4733 | Phage-related protein, tail protein J | NA |
| UHGV-1472693_13 | Structural annotation | PF00629, PF20073, NF033675 | NA | NA |
| UHGV-1472693_18 | Pfam | PF20459 | NA | DUF6712 |
| UHGV-1472693_18 | Structural annotation | PF20459 | NA | NA |
| UHGV-1472693_20 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1472693_20 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-1472693_20 | UniRef90 | UniRef90_A0A255TPS1 | Methyltransferase | NA |
| UHGV-1472693_20 | eggNOG-mapper | 483215.BACFIN_05771 | Belongs to the N(4) N(6)-methyltransferase family | NA |
| UHGV-1472693_20 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-1472693_20 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1472693_20 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1472693_20 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-1472693_21 | eggNOG-mapper | 1235803.C825_03414 | NA | NA |
| UHGV-1472693_21 | Structural annotation | PF05136, MF_04135, TIGR01540, COG5518 | NA | NA |
| UHGV-1472693_22 | Structural annotation | PF13619 | NA | NA |
| UHGV-1472693_23 | PHROG | phrog_200 | lipoprotein | other |
| UHGV-1472693_23 | UniRef90 | UniRef90_A0A3R6J4I4 | SPFH domain-containing protein | NA |
| UHGV-1472693_23 | eggNOG-mapper | 1122989.KB898587_gene2262 | SPFH domain / Band 7 family | NA |
| UHGV-1472693_23 | Pfam | PF01145 | SPFH domain / Band 7 family | Band_7 |
| UHGV-1472693_23 | COG | COG0330 | Regulator of protease activity HflC, stomatin/prohibitin superfamily | NA |
| UHGV-1472693_23 | Structural annotation | PF01145, MF_01562, NF008181, COG2268 | NA | NA |
| UHGV-1472693_28 | UniRef90 | UniRef90_A0A3C1E386 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1472693_31 | PHROG | phrog_1374 | NA | unknown function |
| UHGV-1472693_31 | Pfam | PF10269 | Transmembrane Fragile-X-F protein | Tmemb_185A |
| UHGV-1472693_34 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-1472693_34 | UniRef90 | UniRef90_UPI001F45D98B | YopX family protein | NA |
| UHGV-1472693_34 | eggNOG-mapper | 1347393.HG726022_gene3579 | YopX protein | NA |
| UHGV-1472693_34 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-1472693_34 | NCBIFam | TIGR01671.1 | phage conserved hypothetical protein TIGR01671 | NA |
| UHGV-1472693_34 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-1472693_35 | PHROG | phrog_11581 | NA | unknown function |
| UHGV-1472693_35 | eggNOG-mapper | 470145.BACCOP_01179 | NA | NA |
| UHGV-1472693_39 | PHROG | phrog_874 | NA | unknown function |
| UHGV-1472693_39 | eggNOG-mapper | 762968.HMPREF9441_00541 | NA | NA |
| UHGV-1472693_39 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-1472693_44 | Structural annotation | PF10628 | NA | NA |
| UHGV-1472693_47 | KOfam | K21703 | cbbR, cmpR, ndhR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator | NA |
| UHGV-1472693_47 | PHROG | phrog_3736 | NA | unknown function |
| UHGV-1472693_47 | UniRef90 | UniRef90_A0A353E8E6 | HTH lysR-type domain-containing protein | NA |
| UHGV-1472693_47 | eggNOG-mapper | 1317122.ATO12_13660 | LysR substrate binding domain | NA |
| UHGV-1472693_47 | Pfam | PF00126 | Bacterial regulatory helix-turn-helix protein, lysR family | HTH_1 |
| UHGV-1472693_47 | Pfam | PF03466 | LysR substrate binding domain | LysR_substrate |
| UHGV-1472693_47 | COG | COG0583 | DNA-binding transcriptional regulator, LysR family | NA |
| UHGV-1472693_47 | Structural annotation | PF03466, PF00126, MF_01233, NF040786, COG0583 | NA | NA |
| UHGV-1472693_48 | Structural annotation | TIGR01603, COG5437 | NA | NA |
| UHGV-1472693_49 | Structural annotation | PF05065, PF18998, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1472693_50 | KOfam | K21511 | GPC; capsid assembly protease [EC:3.4.21.-] | NA |
| UHGV-1472693_50 | PHROG | phrog_53 | head maturation protease | head and packaging |
| UHGV-1472693_50 | UniRef90 | UniRef90_A0A2L2WN07 | Signal peptide peptidase SppA, 36K type | NA |
| UHGV-1472693_50 | eggNOG-mapper | 1236504.HMPREF2132_01855 | serine-type peptidase activity | NA |
| UHGV-1472693_50 | Pfam | PF01343 | Peptidase family S49 | Peptidase_S49 |
| UHGV-1472693_50 | COG | COG0616 | Periplasmic serine protease, ClpP class | NA |
| UHGV-1472693_50 | Structural annotation | PF01343, MF_00444, TIGR00706, COG0616 | NA | NA |
| UHGV-1472693_51 | Structural annotation | PF11550, COG5437 | NA | NA |
| UHGV-1472693_54 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-1472693_54 | UniRef90 | UniRef90_A0A353E7W6 | MazG domain-containing protein | NA |
| UHGV-1472693_54 | eggNOG-mapper | 1236504.HMPREF2132_01780 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-1472693_54 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-1472693_54 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-1472693_54 | Structural annotation | TIGR03188, COG1694 | NA | NA |
| UHGV-1472693_55 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-1472693_55 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-1472693_55 | UniRef90 | UniRef90_A0A8F0WBE8 | Flavin-dependent thymidylate synthase | NA |
| UHGV-1472693_55 | eggNOG-mapper | 1236504.HMPREF2132_01775 | thymidylate synthase (FAD) activity | NA |
| UHGV-1472693_55 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-1472693_55 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-1472693_55 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-1472693_56 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-1472693_56 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-1472693_56 | UniRef90 | UniRef90_A0A354WXC5 | Guanylate kinase | NA |
| UHGV-1472693_56 | eggNOG-mapper | 1433126.BN938_1741 | Guanylate kinase | NA |
| UHGV-1472693_56 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-1472693_56 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-1472693_56 | Structural annotation | PF00625, MF_00328, TIGR03263, COG0194 | NA | NA |
| UHGV-1472693_57 | UniRef90 | UniRef90_A0A2L2WND9 | Primase C terminal 2 | NA |
| UHGV-1472693_57 | eggNOG-mapper | 1236504.HMPREF2132_01765 | Primase C terminal 2 (PriCT-2) | NA |
| UHGV-1472693_57 | PADLOC | drt-cluster64 | DRT | DRT |
| UHGV-1472693_57 | Pfam | PF08800 | BT4734-like, N-terminal domain | BT4734-like_N |
| UHGV-1472693_57 | Pfam | PF08707 | Primase C terminal 2 (PriCT-2) | PriCT_2 |
| UHGV-1472693_57 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-1472693_57 | Structural annotation | PF08800, NF040562 | NA | NA |
| UHGV-1472693_58 | PHROG | phrog_25337 | tail length tape measure protein | tail |
| UHGV-1472693_58 | eggNOG-mapper | 1236504.HMPREF2132_01670 | tail tape measure protein, TP901 family | NA |
| UHGV-1472693_58 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-1472693_58 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1472693_58 | Structural annotation | PF10145, TIGR01760, COG5280 | NA | NA |
| UHGV-1472693_60 | Structural annotation | PF20765 | NA | NA |
| UHGV-1472693_61 | UniRef90 | UniRef90_UPI001C2BD57F | phage holin family protein | NA |
| UHGV-1472693_61 | eggNOG-mapper | 457424.BFAG_02443 | NA | NA |
| UHGV-1472693_61 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-1472693_61 | Structural annotation | TIGR01593 | NA | NA |
| UHGV-1472693_64 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1472693_64 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1472693_64 | UniRef90 | UniRef90_A0A2L2WN54 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1472693_64 | eggNOG-mapper | 762982.HMPREF9442_01221 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-1472693_64 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1472693_64 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1472693_64 | Structural annotation | PF01507, MF_00064, NF006327, COG0175 | NA | NA |
| UHGV-1472693_65 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-1472693_65 | UniRef90 | UniRef90_A0A096B9T1 | Conjugal transfer protein | NA |
| UHGV-1472693_65 | eggNOG-mapper | 1236504.HMPREF2132_01885 | DNA restriction-modification system | NA |
| UHGV-1472693_65 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-1472693_65 | Structural annotation | PF03848, MF_02100, NF000058, COG2263 | NA | NA |
| UHGV-1472693_66 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1472693_66 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-1472693_66 | UniRef90 | UniRef90_UPI001C38B218 | site-specific DNA-methyltransferase | NA |
| UHGV-1472693_66 | eggNOG-mapper | 1196028.ALEF01000043_gene479 | DNA methylase | NA |
| UHGV-1472693_66 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-1472693_66 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1472693_66 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1472693_66 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-1472693_68 | eggNOG-mapper | 1002367.HMPREF0673_02207 | NA | NA |
| UHGV-1472693_68 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1472693_74 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-1472693_74 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-1472693_74 | UniRef90 | UniRef90_A0A7X6VW07 | Beta sliding clamp | NA |
| UHGV-1472693_74 | eggNOG-mapper | 1236504.HMPREF2132_01710 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-1472693_74 | Pfam | PF00712 | DNA polymerase III beta subunit, N-terminal domain | DNA_pol3_beta |
| UHGV-1472693_74 | Pfam | PF02768 | DNA polymerase III beta subunit, C-terminal domain | DNA_pol3_beta_3 |
| UHGV-1472693_74 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-1472693_74 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-1472693_79 | UniRef90 | UniRef90_A0A096AGU9 | FHA domain-containing protein | NA |
| UHGV-1472693_79 | eggNOG-mapper | 1236504.HMPREF2132_01700 | DNA primase activity | NA |
| UHGV-1472693_79 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-1472693_79 | Structural annotation | PF05272, PF01807, MF_00974, MF_00016, NF005477, COG3378, COG0358 | NA | NA |
| UHGV-1472693_81 | PHROG | phrog_255 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1472693_81 | UniRef90 | UniRef90_A0A355U3Z6 | NA | NA |
| UHGV-1472693_81 | eggNOG-mapper | 1236504.HMPREF2132_01690 | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease | NA |
| UHGV-1472693_81 | Pfam | PF16473 | 3'-5' exoribonuclease Rv2179c-like domain | Rv2179c-like |
| UHGV-1472693_81 | COG | COG0847 | DNA polymerase III, epsilon subunit or related 3'-5' exonuclease | NA |
| UHGV-1472693_81 | Structural annotation | PF16473, MF_00157, TIGR01298, COG5018 | NA | NA |
| UHGV-1472693_83 | Structural annotation | COG3655 | NA | NA |
| UHGV-1472693_84 | Structural annotation | PF17457 | NA | NA |
| UHGV-1472693_87 | UniRef90 | UniRef90_A0A6G1TZW9 | Replication initiation protein | NA |
| UHGV-1472693_87 | eggNOG-mapper | 1284775.HMPREF1640_05070 | Initiator RepB protein | NA |
| UHGV-1472693_87 | Pfam | PF21205 | Initiator Rep protein, WH2 | Rep3_C |
| UHGV-1472693_87 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-1472693_87 | Structural annotation | PF20964, PF07112, NF010305, COG5527 | NA | NA |
| UHGV-1472693_88 | Structural annotation | PF12502, MF_02248 | NA | NA |
| UHGV-1472693_89 | Structural annotation | PF03869, NF010302, COG3905 | NA | NA |
| UHGV-1472693_90 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-1472693_90 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-1472693_90 | UniRef90 | UniRef90_A0A095Z6L5 | AAA_31 domain-containing protein | NA |
| UHGV-1472693_90 | eggNOG-mapper | 1236504.HMPREF2132_02105 | CobQ CobB MinD ParA nucleotide binding domain | NA |
| UHGV-1472693_90 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-1472693_90 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-1472693_90 | Structural annotation | PF13614, MF_00533, NF041283, COG1192 | NA | NA |
| UHGV-1472693_91 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-1472693_91 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1472693_91 | UniRef90 | UniRef90_A0A521P3I1 | DNA ligase | NA |
| UHGV-1472693_91 | eggNOG-mapper | 393921.HQ45_04010 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-1472693_91 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-1472693_91 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-1472693_91 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1472693_91 | Structural annotation | PF01653, PF03120, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-1472693_92 | Structural annotation | PF06289, COG1582 | NA | NA |
| UHGV-1472693_96 | KOfam | K23779 | sutR; XRE family transcriptional regulator, regulator of sulfur utilization | NA |
| UHGV-1472693_96 | PHROG | phrog_1373 | transcriptional regulator | transcription regulation |
| UHGV-1472693_96 | UniRef90 | UniRef90_A0A419S8Y6 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1472693_96 | eggNOG-mapper | 679937.Bcop_2150 | Helix-turn-helix domain | NA |
| UHGV-1472693_96 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1472693_96 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1472693_96 | Structural annotation | PF13560, TIGR03070, COG1396 | NA | NA |
| UHGV-1472693_99 | Structural annotation | PF12857 | NA | NA |
| UHGV-1472693_103 | UniRef90 | UniRef90_UPI001EFF9E51 | phage antirepressor KilAC domain-containing protein | NA |
| UHGV-1472693_103 | eggNOG-mapper | 1235803.C825_02646 | BRO family, N-terminal domain | NA |
| UHGV-1472693_103 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-1472693_103 | Structural annotation | COG3561 | NA | NA |
| UHGV-1472693_108 | eggNOG-mapper | 1433126.BN938_1801 | NA | NA |
| UHGV-1472693_108 | Pfam | PF18847 | Large polyvalent protein associated domain 29 | LPD29 |