| UHGV-1487877_3 | UniRef90 | UniRef90_A0A318EMC2 | DNA-packaging protein gp3 | NA |
| UHGV-1487877_7 | KOfam | K17081 | PHB2; prohibitin 2 | NA |
| UHGV-1487877_7 | PHROG | phrog_200 | lipoprotein | other |
| UHGV-1487877_7 | UniRef90 | UniRef90_A0A2V2D8I0 | Membrane protease | NA |
| UHGV-1487877_7 | eggNOG-mapper | 1131462.DCF50_p817 | PFAM SPFH domain Band 7 family | NA |
| UHGV-1487877_7 | Pfam | PF01145 | SPFH domain / Band 7 family | Band_7 |
| UHGV-1487877_7 | COG | COG0330 | Regulator of protease activity HflC, stomatin/prohibitin superfamily | NA |
| UHGV-1487877_7 | Structural annotation | PF01145, MF_01562, NF008181, COG0330 | NA | NA |
| UHGV-1487877_12 | KOfam | K19170 | dndC; DNA sulfur modification protein DndC | NA |
| UHGV-1487877_12 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1487877_12 | UniRef90 | UniRef90_A0A3D2CNF7 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1487877_12 | eggNOG-mapper | 1291050.JAGE01000001_gene2907 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1487877_12 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1487877_12 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1487877_13 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1487877_13 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1487877_13 | UniRef90 | UniRef90_A0A2K4ZFK2 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1487877_13 | eggNOG-mapper | 1235793.C809_04341 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1487877_13 | PADLOC | oMTase_00004 | orphan methyltransferase | RM |
| UHGV-1487877_13 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1487877_13 | Pfam | PF14890 | Intein splicing domain | Intein_splicing |
| UHGV-1487877_13 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1487877_13 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1487877_13 | Structural annotation | PF05203, PF00145, MF_01420, NF011287, TIGR00675, COG1372, COG0270 | NA | NA |
| UHGV-1487877_14 | UniRef90 | UniRef90_UPI00054386A4 | nucleotide pyrophosphohydrolase | NA |
| UHGV-1487877_14 | eggNOG-mapper | 1443125.Z962_p0032 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-1487877_14 | Pfam | PF12643 | MazG-like family | MazG-like |
| UHGV-1487877_14 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-1487877_14 | Structural annotation | COG1694 | NA | NA |
| UHGV-1487877_15 | PHROG | phrog_111 | DNA methyltransferase | other |
| UHGV-1487877_15 | UniRef90 | UniRef90_A0A1G8EL36 | Site-specific DNA-methyltransferase (Adenine-specific) | NA |
| UHGV-1487877_15 | eggNOG-mapper | 411468.CLOSCI_00567 | DNA N-6-adenine-methyltransferase | NA |
| UHGV-1487877_15 | PADLOC | oMTase_00015 | orphan methyltransferase | RM |
| UHGV-1487877_15 | Pfam | PF05869 | DNA N-6-adenine-methyltransferase (Dam) | Dam |
| UHGV-1487877_15 | Structural annotation | PF05869, MF_03187, TIGR01712, COG2263 | NA | NA |
| UHGV-1487877_16 | KOfam | K06919 | K06919; putative DNA primase/helicase | NA |
| UHGV-1487877_16 | PHROG | phrog_256 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1487877_16 | UniRef90 | UniRef90_UPI000426557F | phage/plasmid primase, P4 family | NA |
| UHGV-1487877_16 | eggNOG-mapper | 1121087.AUCK01000006_gene570 | Virulence-associated protein E | NA |
| UHGV-1487877_16 | Pfam | PF08706 | D5 N terminal like | D5_N |
| UHGV-1487877_16 | Pfam | PF19263 | NA | DUF5906 |
| UHGV-1487877_16 | Pfam | PF03288 | Poxvirus D5 protein-like | Pox_D5 |
| UHGV-1487877_16 | NCBIFam | TIGR01613.1 | phage/plasmid primase, P4 family | NA |
| UHGV-1487877_16 | COG | COG3378 | DNA primase, phage- or plasmid-associated | NA |
| UHGV-1487877_19 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-1487877_19 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1487877_19 | UniRef90 | UniRef90_A0A0J6HBT6 | DEAD/DEAH box helicase | NA |
| UHGV-1487877_19 | eggNOG-mapper | 1274524.BSONL12_06073 | SNF2 family N-terminal domain | NA |
| UHGV-1487877_19 | PADLOC | ZorD1_00007 | SWI2/SNF2 helicase, Mrr-like nuclease | Zorya |
| UHGV-1487877_19 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-1487877_19 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-1487877_19 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-1487877_19 | Structural annotation | PF16203, PF04851, MF_01821, NF041790, COG0553 | NA | NA |
| UHGV-1487877_20 | PHROG | phrog_236 | nucleotide kinase | other |
| UHGV-1487877_20 | UniRef90 | UniRef90_A0A3M1R3H0 | NA | NA |
| UHGV-1487877_20 | eggNOG-mapper | 546273.VEIDISOL_00707 | NA | NA |
| UHGV-1487877_20 | Pfam | PF11753 | NA | DUF3310 |
| UHGV-1487877_21 | PHROG | phrog_93 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1487877_21 | UniRef90 | UniRef90_UPI00164BDA89 | VRR-NUC domain-containing protein | NA |
| UHGV-1487877_21 | eggNOG-mapper | 1095750.HMPREF9970_1023 | VRR-NUC domain protein | NA |
| UHGV-1487877_21 | Pfam | PF08774 | VRR-NUC domain | VRR_NUC |
| UHGV-1487877_22 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-1487877_22 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-1487877_23 | PHROG | phrog_24884 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-1487877_23 | UniRef90 | UniRef90_UPI000F63E3C3 | FAD-dependent thymidylate synthase | NA |
| UHGV-1487877_23 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-1487877_24 | KOfam | K02334 | dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7] | NA |
| UHGV-1487877_24 | PHROG | phrog_17 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1487877_24 | UniRef90 | UniRef90_A0A1G9QUU8 | DNA polymerase | NA |
| UHGV-1487877_24 | eggNOG-mapper | 883156.HMPREF9282_00936 | DNA polymerase | NA |
| UHGV-1487877_24 | Pfam | PF00476 | DNA polymerase family A | DNA_pol_A |
| UHGV-1487877_24 | COG | COG0749 | DNA polymerase I, 3'-5' exonuclease and polymerase domains | NA |
| UHGV-1487877_24 | Structural annotation | PF00476, MF_04101, NF011540, COG0749 | NA | NA |
| UHGV-1487877_25 | PHROG | phrog_112 | Gp2.5-like ssDNA binding protein and ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1487877_25 | UniRef90 | UniRef90_A0A658K131 | NA | NA |
| UHGV-1487877_25 | eggNOG-mapper | 1274524.BSONL12_06028 | NA | NA |
| UHGV-1487877_25 | Pfam | PF10991 | Enterobacter phage Enc34, ssDNA-binding protein | Enc34_ssDNA-bd |
| UHGV-1487877_25 | Structural annotation | PF10991, MF_04153 | NA | NA |
| UHGV-1487877_26 | KOfam | K07465 | K07465; putative RecB family exonuclease | NA |
| UHGV-1487877_26 | PHROG | phrog_69 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1487877_26 | UniRef90 | UniRef90_UPI00156EF32D | NA | NA |
| UHGV-1487877_26 | eggNOG-mapper | 1274524.BSONL12_06023 | NA | NA |
| UHGV-1487877_26 | Pfam | PF10926 | NA | DUF2800 |
| UHGV-1487877_26 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-1487877_26 | Structural annotation | PF10926, MF_03030, TIGR00372, COG2887 | NA | NA |
| UHGV-1487877_29 | Pfam | PF12728 | Helix-turn-helix domain | HTH_17 |
| UHGV-1487877_29 | Structural annotation | PF12728, NF040990 | NA | NA |
| UHGV-1487877_31 | eggNOG-mapper | 760568.Desku_0919 | NA | NA |
| UHGV-1487877_31 | Structural annotation | PF03787, TIGR02581, COG1604 | NA | NA |
| UHGV-1487877_32 | PHROG | phrog_7940 | NA | unknown function |
| UHGV-1487877_32 | UniRef90 | UniRef90_F8IGN7 | Prophage antirepressor | NA |
| UHGV-1487877_32 | eggNOG-mapper | 1048834.TC41_2417 | COG3617 Prophage antirepressor | NA |
| UHGV-1487877_32 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-1487877_32 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-1487877_33 | UniRef90 | UniRef90_A0A7G5N297 | DNA-binding protein | NA |
| UHGV-1487877_33 | eggNOG-mapper | 1226325.HMPREF1548_06746 | NA | NA |
| UHGV-1487877_33 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-1487877_34 | UniRef90 | UniRef90_A0A2N0KEJ2 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1487877_34 | eggNOG-mapper | 1226325.HMPREF1548_06747 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-1487877_34 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1487877_36 | UniRef90 | UniRef90_A0A417ACE5 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1487877_36 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-1487877_37 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1487877_37 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1487877_37 | UniRef90 | UniRef90_A0A7X5KRB3 | Helix-turn-helix transcriptional regulator | NA |
| UHGV-1487877_37 | eggNOG-mapper | 1196322.A370_02092 | sequence-specific DNA binding | NA |
| UHGV-1487877_37 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1487877_37 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1487877_37 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1487877_39 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1487877_39 | PHROG | phrog_2967 | transcriptional regulator | transcription regulation |
| UHGV-1487877_39 | UniRef90 | UniRef90_A0A829Z8F4 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1487877_39 | eggNOG-mapper | 864563.HMPREF9166_1835 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-1487877_39 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1487877_39 | Pfam | PF13560 | Helix-turn-helix domain | HTH_31 |
| UHGV-1487877_39 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1487877_40 | KOfam | K14059 | int; integrase | NA |
| UHGV-1487877_40 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1487877_40 | UniRef90 | UniRef90_UPI001C117EE7 | site-specific integrase | NA |
| UHGV-1487877_40 | eggNOG-mapper | 1235790.C805_01692 | Belongs to the 'phage' integrase family | NA |
| UHGV-1487877_40 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1487877_40 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-1487877_40 | Structural annotation | PF00589, PF14659, MF_02055, TIGR02224, COG4974 | NA | NA |
| UHGV-1487877_41 | KOfam | K06218 | relE, stbE; mRNA interferase RelE/StbE | NA |
| UHGV-1487877_41 | PHROG | phrog_1213 | RelE-like toxin | moron, auxiliary metabolic gene and host takeover |
| UHGV-1487877_41 | UniRef90 | UniRef90_A0A374BM66 | Type II toxin-antitoxin system RelE/ParE family toxin | NA |
| UHGV-1487877_41 | eggNOG-mapper | 904296.HMPREF9124_0080 | ParE toxin of type II toxin-antitoxin system, parDE | NA |
| UHGV-1487877_41 | Pfam | PF05016 | ParE toxin of type II toxin-antitoxin system, parDE | ParE_toxin |
| UHGV-1487877_41 | COG | COG2026 | mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system | NA |
| UHGV-1487877_41 | Structural annotation | PF05016, TIGR00053, COG2026 | NA | NA |
| UHGV-1487877_42 | PHROG | phrog_4085 | NA | unknown function |
| UHGV-1487877_42 | UniRef90 | UniRef90_A0A412KRP6 | Ribbon-helix-helix protein, CopG family | NA |
| UHGV-1487877_42 | eggNOG-mapper | 500635.MITSMUL_05167 | NA | NA |
| UHGV-1487877_42 | Pfam | PF19807 | NA | DUF6290 |
| UHGV-1487877_42 | Structural annotation | PF19807, NF041418, COG4710 | NA | NA |
| UHGV-1487877_43 | KOfam | K01153 | hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] | NA |
| UHGV-1487877_43 | PHROG | phrog_3830 | NA | unknown function |
| UHGV-1487877_43 | UniRef90 | UniRef90_A0A1C6K5N6 | Type I restriction enzyme endonuclease subunit | NA |
| UHGV-1487877_43 | eggNOG-mapper | 1226322.HMPREF1545_02288 | Subunit R is required for both nuclease and ATPase activities, but not for modification | NA |
| UHGV-1487877_43 | PADLOC | REase_I_00001 | Type I restriction enzyme | RM |
| UHGV-1487877_43 | Pfam | PF04313 | Type I restriction enzyme R protein N terminus (HSDR_N) | HSDR_N |
| UHGV-1487877_43 | Pfam | PF18766 | SWI2/SNF2 ATPase | SWI2_SNF2 |
| UHGV-1487877_43 | Pfam | PF11867 | Type I restriction enzyme HindI endonuclease subunit-like, C-terminal | T1RH-like_C |
| UHGV-1487877_43 | NCBIFam | TIGR00348.1 | HsdR family type I site-specific deoxyribonuclease | NA |
| UHGV-1487877_43 | COG | COG0610 | Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ... | NA |
| UHGV-1487877_43 | Structural annotation | PF11867, PF18766, PF04313, PF16203, MF_00967, TIGR00348, COG0610 | NA | NA |
| UHGV-1487877_45 | eggNOG-mapper | 411459.RUMOBE_01436 | NA | NA |
| UHGV-1487877_46 | KOfam | K01154 | hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] | NA |
| UHGV-1487877_46 | PHROG | phrog_2668 | NA | unknown function |
| UHGV-1487877_46 | UniRef90 | UniRef90_U2QEG3 | Type I restriction modification DNA specificity domain protein | NA |
| UHGV-1487877_46 | eggNOG-mapper | 1226322.HMPREF1545_02286 | type I restriction modification DNA specificity domain | NA |
| UHGV-1487877_46 | PADLOC | Specificity_I_00081 | Type I specificity subunit | RM |
| UHGV-1487877_46 | Pfam | PF01420 | Type I restriction modification DNA specificity domain | Methylase_S |
| UHGV-1487877_46 | COG | COG0732 | Restriction endonuclease S subunit | NA |
| UHGV-1487877_46 | Structural annotation | PF01420, NF007278, COG0732 | NA | NA |
| UHGV-1487877_47 | KOfam | K03427 | hsdM; type I restriction enzyme M protein [EC:2.1.1.72] | NA |
| UHGV-1487877_47 | PHROG | phrog_2713 | NA | unknown function |
| UHGV-1487877_47 | UniRef90 | UniRef90_A0A2A7BAE3 | Site-specific DNA-methyltransferase (adenine-specific) | NA |
| UHGV-1487877_47 | eggNOG-mapper | 904296.HMPREF9124_2008 | HsdM N-terminal domain | NA |
| UHGV-1487877_47 | PADLOC | MTase_I_00018 | Type I methyltransferase | RM |
| UHGV-1487877_47 | Pfam | PF12161 | HsdM N-terminal domain | HsdM_N |
| UHGV-1487877_47 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-1487877_47 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-1487877_49 | UniRef90 | UniRef90_A0A829Z7Q5 | Serine/threonine-protein kinase CtkA | NA |
| UHGV-1487877_49 | eggNOG-mapper | 641112.ACOK01000096_gene938 | NA | NA |
| UHGV-1487877_49 | COG | COG3550 | Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module | NA |