| UHGV-1497155_1 | KOfam | K01448 | amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-1497155_1 | PHROG | phrog_435 | endolysin | lysis |
| UHGV-1497155_1 | UniRef90 | UniRef90_UPI000D659E9B | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1497155_1 | eggNOG-mapper | 1256908.HMPREF0373_00462 | Cell wall hydrolase autolysin | NA |
| UHGV-1497155_1 | Pfam | PF01520 | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
| UHGV-1497155_1 | Pfam | PF21540 | Choline-binding repeat | Choline_bind_4 |
| UHGV-1497155_1 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1497155_1 | Structural annotation | PF01520, PF18342, MF_00417, TIGR02883, COG0860, COG4991 | NA | NA |
| UHGV-1497155_3 | KOfam | K03530 | hupB; DNA-binding protein HU-beta | NA |
| UHGV-1497155_3 | PHROG | phrog_379 | DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_3 | UniRef90 | UniRef90_A0A7X8I2Z1 | HU family DNA-binding protein | NA |
| UHGV-1497155_3 | eggNOG-mapper | 797515.HMPREF9103_02658 | Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions | NA |
| UHGV-1497155_3 | Pfam | PF00216 | Bacterial DNA-binding protein | Bac_DNA_binding |
| UHGV-1497155_3 | COG | COG0776 | Bacterial nucleoid DNA-binding protein IHF-alpha | NA |
| UHGV-1497155_3 | Structural annotation | PF00216, MF_00381, NF001222, COG0776 | NA | NA |
| UHGV-1497155_5 | PHROG | phrog_284 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_5 | UniRef90 | UniRef90_A0A416FDY8 | Metallophos domain-containing protein | NA |
| UHGV-1497155_5 | eggNOG-mapper | 397291.C804_01076 | NA | NA |
| UHGV-1497155_5 | Structural annotation | PF12850, MF_00325, NF003118, COG1311 | NA | NA |
| UHGV-1497155_6 | Structural annotation | PF09642 | NA | NA |
| UHGV-1497155_7 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-1497155_7 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-1497155_7 | UniRef90 | UniRef90_A0A416TYT0 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-1497155_7 | eggNOG-mapper | 985867.AEWF01000001_gene2257 | Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins | NA |
| UHGV-1497155_7 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-1497155_7 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-1497155_7 | Structural annotation | PF00574, MF_00444, NF009205, COG0740 | NA | NA |
| UHGV-1497155_8 | KOfam | K07576 | K07576; metallo-beta-lactamase family protein | NA |
| UHGV-1497155_8 | PHROG | phrog_36352 | NA | unknown function |
| UHGV-1497155_8 | UniRef90 | UniRef90_A0A415MEG6 | Beta-Casp domain-containing protein | NA |
| UHGV-1497155_8 | eggNOG-mapper | 537007.BLAHAN_05298 | NA | NA |
| UHGV-1497155_8 | Pfam | PF10996 | Beta-Casp domain | Beta-Casp |
| UHGV-1497155_8 | Pfam | PF07521 | Zn-dependent metallo-hydrolase RNA specificity domain | RMMBL |
| UHGV-1497155_8 | COG | COG1236 | RNA processing exonuclease, beta-lactamase fold, Cft2 family | NA |
| UHGV-1497155_8 | Structural annotation | PF16661, PF10996, MF_01491, TIGR03675, COG1236 | NA | NA |
| UHGV-1497155_9 | UniRef90 | UniRef90_UPI0009FE3344 | HU family DNA-binding protein | NA |
| UHGV-1497155_9 | Pfam | PF00216 | Bacterial DNA-binding protein | Bac_DNA_binding |
| UHGV-1497155_10 | PHROG | phrog_8308 | NA | unknown function |
| UHGV-1497155_10 | eggNOG-mapper | 1235802.C823_04534 | NA | NA |
| UHGV-1497155_10 | Structural annotation | PF05183 | NA | NA |
| UHGV-1497155_11 | UniRef90 | UniRef90_UPI001C9A81BF | competence protein CoiA | NA |
| UHGV-1497155_13 | Structural annotation | PF17123 | NA | NA |
| UHGV-1497155_14 | PHROG | phrog_174 | dCMP deaminase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_14 | UniRef90 | UniRef90_A0A416TYA6 | CMP/dCMP-type deaminase domain-containing protein | NA |
| UHGV-1497155_14 | eggNOG-mapper | 97139.C824_00179 | Cytidine and deoxycytidylate deaminase zinc-binding region | NA |
| UHGV-1497155_14 | Pfam | PF00383 | Cytidine and deoxycytidylate deaminase zinc-binding region | dCMP_cyt_deam_1 |
| UHGV-1497155_14 | Structural annotation | PF00383, TIGR02571, COG2131 | NA | NA |
| UHGV-1497155_15 | eggNOG-mapper | 1235800.C819_00452 | NA | NA |
| UHGV-1497155_15 | Structural annotation | PF17589 | NA | NA |
| UHGV-1497155_17 | KOfam | K03657 | uvrD, pcrA; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] | NA |
| UHGV-1497155_17 | PHROG | phrog_1967 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_17 | UniRef90 | UniRef90_A0A416P6Z3 | DNA helicase | NA |
| UHGV-1497155_17 | eggNOG-mapper | 411470.RUMGNA_00086 | NA | NA |
| UHGV-1497155_17 | PADLOC | GajB_00012 | UrvD helicase | Gabija |
| UHGV-1497155_17 | Pfam | PF00580 | UvrD/REP helicase N-terminal domain | UvrD-helicase |
| UHGV-1497155_17 | Pfam | PF13361 | UvrD-like helicase C-terminal domain | UvrD_C |
| UHGV-1497155_17 | COG | COG0210 | Superfamily I DNA or RNA helicase | NA |
| UHGV-1497155_17 | Structural annotation | PF00580, PF13361, PF12073, MF_01920, NF008743, COG0210 | NA | NA |
| UHGV-1497155_18 | PHROG | phrog_36702 | NA | unknown function |
| UHGV-1497155_22 | UniRef90 | UniRef90_A0A316SEC9 | Modification methylase | NA |
| UHGV-1497155_22 | eggNOG-mapper | 546267.NEIPOLOT_00641 | Adenine-specific methyltransferase EcoRI | NA |
| UHGV-1497155_22 | PADLOC | MTase_II_00083 | Type II methyltransferase | RM |
| UHGV-1497155_22 | Pfam | PF13651 | Adenine-specific methyltransferase EcoRI | EcoRI_methylase |
| UHGV-1497155_22 | Structural annotation | PF13651, MF_00607, NF012222, COG2263 | NA | NA |
| UHGV-1497155_26 | Structural annotation | PF09274 | NA | NA |
| UHGV-1497155_27 | Structural annotation | PF20082 | NA | NA |
| UHGV-1497155_31 | Structural annotation | PF14317, NF033677, COG1582 | NA | NA |
| UHGV-1497155_32 | Structural annotation | PF06243 | NA | NA |
| UHGV-1497155_34 | UniRef90 | UniRef90_A0A3R8L119 | XRE family transcriptional regulator | NA |
| UHGV-1497155_35 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-1497155_35 | PHROG | phrog_3 | transcriptional repressor | transcription regulation |
| UHGV-1497155_35 | UniRef90 | UniRef90_A0A3R6KC39 | XRE family transcriptional regulator | NA |
| UHGV-1497155_35 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1497155_35 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1497155_35 | Structural annotation | PF06114, PF01381, MF_00584, NF038139, COG2856, COG1476 | NA | NA |
| UHGV-1497155_36 | PHROG | phrog_353 | toxin | moron, auxiliary metabolic gene and host takeover |
| UHGV-1497155_36 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-1497155_36 | Structural annotation | PF07927, COG1724 | NA | NA |
| UHGV-1497155_37 | Structural annotation | TIGR04550 | NA | NA |
| UHGV-1497155_46 | Structural annotation | PF18300, MF_01549 | NA | NA |
| UHGV-1497155_47 | PHROG | phrog_4273 | NA | unknown function |
| UHGV-1497155_48 | UniRef90 | UniRef90_UPI001C122BAC | antirestriction protein ArdA | NA |
| UHGV-1497155_49 | PHROG | phrog_5149 | NA | unknown function |
| UHGV-1497155_52 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-1497155_52 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_52 | UniRef90 | UniRef90_A0A415ME79 | DNA_pol3_beta_2 domain-containing protein | NA |
| UHGV-1497155_52 | eggNOG-mapper | 1410628.JNKS01000042_gene830 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-1497155_52 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-1497155_52 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-1497155_53 | PHROG | phrog_6186 | NA | unknown function |
| UHGV-1497155_53 | eggNOG-mapper | 537013.CLOSTMETH_01299 | NA | NA |
| UHGV-1497155_58 | Structural annotation | PF14207 | NA | NA |
| UHGV-1497155_70 | eggNOG-mapper | 537007.BLAHAN_05426 | NA | NA |
| UHGV-1497155_71 | eggNOG-mapper | 880074.BARVI_02400 | NA | NA |
| UHGV-1497155_77 | eggNOG-mapper | 1347393.HG726021_gene719 | NA | NA |
| UHGV-1497155_79 | eggNOG-mapper | 397290.C810_01718 | NA | NA |
| UHGV-1497155_80 | UniRef90 | UniRef90_UPI000E4AA629 | helix-turn-helix domain-containing protein | NA |
| UHGV-1497155_80 | eggNOG-mapper | 536232.CLM_2560 | SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains | NA |
| UHGV-1497155_80 | Structural annotation | PF12728, PF13936, TIGR01764, COG3311 | NA | NA |
| UHGV-1497155_81 | UniRef90 | UniRef90_A0A1Q9J4Y8 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1497155_83 | PHROG | phrog_1510 | superinfection exclusion | moron, auxiliary metabolic gene and host takeover |
| UHGV-1497155_83 | UniRef90 | UniRef90_K1TNQ5 | Superinfection exclusion protein | NA |
| UHGV-1497155_83 | eggNOG-mapper | 1304866.K413DRAFT_3384 | Superinfection exclusion protein, bacteriophage P22 | NA |
| UHGV-1497155_83 | Pfam | PF17420 | Superinfection exclusion gene product 17 | GP17 |
| UHGV-1497155_83 | Structural annotation | PF17420 | NA | NA |
| UHGV-1497155_86 | eggNOG-mapper | 1123237.Salmuc_01650 | NA | NA |
| UHGV-1497155_90 | UniRef90 | UniRef90_A0A3R6S6Z1 | SpoVT-AbrB domain-containing protein | NA |
| UHGV-1497155_90 | Structural annotation | PF19824 | NA | NA |
| UHGV-1497155_93 | PHROG | phrog_6452 | NA | unknown function |
| UHGV-1497155_93 | eggNOG-mapper | 397291.C804_05687 | NA | NA |
| UHGV-1497155_94 | Pfam | PF14078 | NA | DUF4259 |
| UHGV-1497155_98 | Structural annotation | PF13542 | NA | NA |
| UHGV-1497155_100 | KOfam | K03733 | xerC; integrase/recombinase XerC | NA |
| UHGV-1497155_100 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1497155_100 | UniRef90 | UniRef90_A0A0V8QCA5 | Tyr recombinase domain-containing protein | NA |
| UHGV-1497155_100 | eggNOG-mapper | 411470.RUMGNA_00044 | Belongs to the 'phage' integrase family | NA |
| UHGV-1497155_100 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1497155_100 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-1497155_100 | Structural annotation | PF00589, MF_01808, NF003462, COG4974 | NA | NA |
| UHGV-1497155_101 | KOfam | K07339 | hicA; mRNA interferase HicA [EC:3.1.-.-] | NA |
| UHGV-1497155_101 | PHROG | phrog_353 | toxin | moron, auxiliary metabolic gene and host takeover |
| UHGV-1497155_101 | UniRef90 | UniRef90_UPI000682DFBF | type II toxin-antitoxin system HicA family toxin | NA |
| UHGV-1497155_101 | eggNOG-mapper | 476272.RUMHYD_01978 | periplasmic or secreted lipoprotein | NA |
| UHGV-1497155_101 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-1497155_101 | COG | COG1724 | Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family | NA |
| UHGV-1497155_101 | Structural annotation | PF07927, COG1724 | NA | NA |
| UHGV-1497155_102 | KOfam | K18843 | hicB; antitoxin HicB | NA |
| UHGV-1497155_102 | PHROG | phrog_497 | toxin-antitoxin system HicB-like | moron, auxiliary metabolic gene and host takeover |
| UHGV-1497155_102 | UniRef90 | UniRef90_UPI000D1102B6 | type II toxin-antitoxin system HicB family antitoxin | NA |
| UHGV-1497155_102 | eggNOG-mapper | 476272.RUMHYD_01977 | HicB_like antitoxin of bacterial toxin-antitoxin system | NA |
| UHGV-1497155_102 | Pfam | PF15919 | HicB_like antitoxin of bacterial toxin-antitoxin system | HicB_lk_antitox |
| UHGV-1497155_102 | COG | COG1598 | Antitoxin component HicB of the HicAB toxin-antitoxin system | NA |
| UHGV-1497155_102 | Structural annotation | PF15919, COG1598 | NA | NA |
| UHGV-1497155_103 | KOfam | K07727 | K07727; putative transcriptional regulator | NA |
| UHGV-1497155_103 | PHROG | phrog_2967 | transcriptional regulator | transcription regulation |
| UHGV-1497155_103 | UniRef90 | UniRef90_UPI00164AD209 | helix-turn-helix transcriptional regulator | NA |
| UHGV-1497155_103 | eggNOG-mapper | 1347392.CCEZ01000043_gene479 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-1497155_103 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1497155_103 | Structural annotation | PF13443, MF_00535, NF041951, COG3655 | NA | NA |
| UHGV-1497155_104 | KOfam | K07171 | mazF, ndoA, chpA; mRNA interferase MazF [EC:3.1.-.-] | NA |
| UHGV-1497155_104 | PHROG | phrog_1936 | MazF-like growth inhibitor | moron, auxiliary metabolic gene and host takeover |
| UHGV-1497155_104 | UniRef90 | UniRef90_A0A3E2NB84 | Type II toxin-antitoxin system PemK/MazF family toxin | NA |
| UHGV-1497155_104 | eggNOG-mapper | 397291.C804_00995 | Toxic component of a toxin-antitoxin (TA) module | NA |
| UHGV-1497155_104 | Pfam | PF02452 | PemK-like, MazF-like toxin of type II toxin-antitoxin system | PemK_toxin |
| UHGV-1497155_104 | COG | COG2337 | mRNA-degrading endonuclease MazF, toxin component of the MazEF toxin-antitoxin module | NA |
| UHGV-1497155_104 | Structural annotation | PF02452, NF007386, COG2337 | NA | NA |
| UHGV-1497155_107 | Structural annotation | PF15188 | NA | NA |
| UHGV-1497155_108 | KOfam | K03091 | sigH; RNA polymerase sporulation-specific sigma factor | NA |
| UHGV-1497155_108 | UniRef90 | UniRef90_A0A1C5WCY3 | RNA polymerase sigma factor, sigma-70 family | NA |
| UHGV-1497155_108 | eggNOG-mapper | 742735.HMPREF9467_00837 | Sigma-70 region 2 | NA |
| UHGV-1497155_108 | Pfam | PF04542 | Sigma-70 region 2 | Sigma70_r2 |
| UHGV-1497155_108 | Structural annotation | PF08281, MF_02064, NF006158, COG1191 | NA | NA |
| UHGV-1497155_109 | UniRef90 | UniRef90_A0A3E2NB90 | NA | NA |
| UHGV-1497155_109 | eggNOG-mapper | 397287.C807_01331 | NA | NA |
| UHGV-1497155_109 | Structural annotation | PF14072, MF_02015, NF041060, COG1479 | NA | NA |
| UHGV-1497155_118 | PHROG | phrog_1735 | NA | unknown function |
| UHGV-1497155_118 | eggNOG-mapper | 1163671.JAGI01000002_gene1273 | Protein conserved in bacteria | NA |
| UHGV-1497155_118 | COG | COG4676 | NA | NA |
| UHGV-1497155_118 | Structural annotation | COG4676 | NA | NA |
| UHGV-1497155_119 | PHROG | phrog_2018 | NA | unknown function |
| UHGV-1497155_119 | eggNOG-mapper | 1163671.JAGI01000002_gene1274 | NA | NA |
| UHGV-1497155_122 | UniRef90 | UniRef90_A0A416U1L4 | NA | NA |
| UHGV-1497155_122 | eggNOG-mapper | 411467.BACCAP_01807 | NA | NA |
| UHGV-1497155_122 | COG | COG4474 | NA | NA |
| UHGV-1497155_122 | Structural annotation | PF06908, MF_01575, NF010181, COG4474 | NA | NA |
| UHGV-1497155_124 | UniRef90 | UniRef90_A0A415TX35 | BAH domain-containing protein | NA |
| UHGV-1497155_124 | eggNOG-mapper | 397290.C810_01492 | NA | NA |
| UHGV-1497155_131 | UniRef90 | UniRef90_A0A3E2WD56 | NA | NA |
| UHGV-1497155_132 | eggNOG-mapper | 1235790.C805_00047 | NA | NA |
| UHGV-1497155_133 | KOfam | K07099 | NA | NA |
| UHGV-1497155_133 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-1497155_133 | UniRef90 | UniRef90_UPI00156FCA5C | metallophosphoesterase family protein | NA |
| UHGV-1497155_133 | eggNOG-mapper | 1410631.JHWZ01000001_gene1011 | Calcineurin-like phosphoesterase superfamily domain | NA |
| UHGV-1497155_133 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-1497155_133 | COG | COG4186 | NA | NA |
| UHGV-1497155_133 | Structural annotation | PF12850, MF_00575, TIGR04123, COG4186 | NA | NA |
| UHGV-1497155_135 | PHROG | phrog_2475 | NA | unknown function |
| UHGV-1497155_135 | eggNOG-mapper | 397291.C804_00943 | NA | NA |
| UHGV-1497155_136 | PHROG | phrog_2574 | NA | unknown function |
| UHGV-1497155_136 | eggNOG-mapper | 397291.C804_00942 | NA | NA |
| UHGV-1497155_139 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1497155_139 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1497155_139 | UniRef90 | UniRef90_A0A1C5WFT2 | Cytosine-specific methyltransferase | NA |
| UHGV-1497155_139 | eggNOG-mapper | 1121115.AXVN01000007_gene3542 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1497155_139 | PADLOC | oMTase_00023 | orphan methyltransferase | RM |
| UHGV-1497155_139 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1497155_139 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1497155_139 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1497155_139 | Structural annotation | PF00145, TIGR00675, COG0270 | NA | NA |
| UHGV-1497155_142 | KOfam | K01537 | ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10] | NA |
| UHGV-1497155_142 | PHROG | phrog_12316 | ATPase | other |
| UHGV-1497155_142 | UniRef90 | UniRef90_A0A414ZR35 | Cation-transporting P-type ATPase | NA |
| UHGV-1497155_142 | eggNOG-mapper | 537007.BLAHAN_05479 | Cation transporter/ATPase, N-terminus | NA |
| UHGV-1497155_142 | Pfam | PF00690 | Cation transporter/ATPase, N-terminus | Cation_ATPase_N |
| UHGV-1497155_142 | Pfam | PF00122 | E1-E2 ATPase | E1-E2_ATPase |
| UHGV-1497155_142 | Pfam | PF00702 | haloacid dehalogenase-like hydrolase | Hydrolase |
| UHGV-1497155_142 | Pfam | PF00689 | Cation transporting ATPase, C-terminus | Cation_ATPase_C |
| UHGV-1497155_142 | NCBIFam | TIGR01494.1 | HAD-IC family P-type ATPase | NA |
| UHGV-1497155_142 | COG | COG0474 | Magnesium-transporting ATPase (P-type) | NA |
| UHGV-1497155_142 | Structural annotation | PF00122, PF00689, PF00702, MF_00285, TIGR01522, COG0474 | NA | NA |
| UHGV-1497155_143 | KOfam | K05795 | terD; tellurium resistance protein TerD | NA |
| UHGV-1497155_143 | PHROG | phrog_5698 | NA | unknown function |
| UHGV-1497155_143 | UniRef90 | UniRef90_A0A414ZR66 | TerD family protein | NA |
| UHGV-1497155_143 | eggNOG-mapper | 592027.CLG_B0188 | resistance protein | NA |
| UHGV-1497155_143 | Pfam | PF02342 | TerD domain | TerD |
| UHGV-1497155_143 | COG | COG2310 | Stress response protein SCP2 | NA |
| UHGV-1497155_143 | Structural annotation | PF02342, COG2310 | NA | NA |
| UHGV-1497155_144 | KOfam | K05795 | terD; tellurium resistance protein TerD | NA |
| UHGV-1497155_144 | PHROG | phrog_5698 | NA | unknown function |
| UHGV-1497155_144 | UniRef90 | UniRef90_A0A414ZR48 | TerD family protein | NA |
| UHGV-1497155_144 | eggNOG-mapper | 1200792.AKYF01000019_gene4559 | Stress protein | NA |
| UHGV-1497155_144 | Pfam | PF02342 | TerD domain | TerD |
| UHGV-1497155_144 | COG | COG2310 | Stress response protein SCP2 | NA |
| UHGV-1497155_144 | Structural annotation | PF02342, COG2310 | NA | NA |
| UHGV-1497155_145 | KOfam | K05795 | terD; tellurium resistance protein TerD | NA |
| UHGV-1497155_145 | PHROG | phrog_5698 | NA | unknown function |
| UHGV-1497155_145 | UniRef90 | UniRef90_A0A414ZR31 | TerD family protein | NA |
| UHGV-1497155_145 | eggNOG-mapper | 1095750.HMPREF9970_1654 | TerD domain | NA |
| UHGV-1497155_145 | Pfam | PF02342 | TerD domain | TerD |
| UHGV-1497155_145 | COG | COG2310 | Stress response protein SCP2 | NA |
| UHGV-1497155_145 | Structural annotation | PF02342, COG2310 | NA | NA |
| UHGV-1497155_146 | PHROG | phrog_33389 | NA | unknown function |
| UHGV-1497155_146 | eggNOG-mapper | 1163671.JAGI01000002_gene1286 | NA | NA |
| UHGV-1497155_146 | Structural annotation | PF04012, NF007974, COG1842 | NA | NA |
| UHGV-1497155_149 | eggNOG-mapper | 476272.RUMHYD_01917 | NA | NA |
| UHGV-1497155_150 | KOfam | K08281 | pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-] | NA |
| UHGV-1497155_150 | PHROG | phrog_19305 | NA | unknown function |
| UHGV-1497155_150 | UniRef90 | UniRef90_S2Y4L8 | Isochorismatase domain-containing protein | NA |
| UHGV-1497155_150 | eggNOG-mapper | 1163671.JAGI01000002_gene1278 | Isochorismatase family | NA |
| UHGV-1497155_150 | Pfam | PF00857 | Isochorismatase family | Isochorismatase |
| UHGV-1497155_150 | COG | COG1335 | Nicotinamidase-related amidase | NA |
| UHGV-1497155_150 | Structural annotation | PF00857, MF_00830, NF008623, COG1335 | NA | NA |
| UHGV-1497155_151 | PHROG | phrog_17662 | NA | unknown function |
| UHGV-1497155_151 | UniRef90 | UniRef90_UPI001899FDF7 | radical SAM protein | NA |
| UHGV-1497155_151 | eggNOG-mapper | 742735.HMPREF9467_00856 | NA | NA |
| UHGV-1497155_151 | Structural annotation | MF_03128, TIGR02495, COG2896 | NA | NA |
| UHGV-1497155_152 | KOfam | K00948 | PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] | NA |
| UHGV-1497155_152 | PHROG | phrog_619 | ribose-phosphate pyrophosphokinase | other |
| UHGV-1497155_152 | UniRef90 | UniRef90_A0A414ZQZ8 | Phosphoribosyl pyrophosphate synthase | NA |
| UHGV-1497155_152 | eggNOG-mapper | 397291.C804_00937 | Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) | NA |
| UHGV-1497155_152 | COG | COG0462 | Phosphoribosylpyrophosphate synthetase | NA |
| UHGV-1497155_152 | Structural annotation | PF14572, MF_00583_B, NF001815, COG0462 | NA | NA |
| UHGV-1497155_153 | KOfam | K03462 | NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12] | NA |
| UHGV-1497155_153 | PHROG | phrog_448 | nicotinamide phosphoribosyl transferase | other |
| UHGV-1497155_153 | UniRef90 | UniRef90_A0A416U273 | Nicotinate phosphoribosyltransferase | NA |
| UHGV-1497155_153 | eggNOG-mapper | 397291.C804_00936 | nicotinate | NA |
| UHGV-1497155_153 | Pfam | PF18127 | Nicotinamide phosphoribosyltransferase, N-terminal domain | NAMPT_N |
| UHGV-1497155_153 | Pfam | PF04095 | Nicotinate phosphoribosyltransferase (NAPRTase) family | NAPRTase |
| UHGV-1497155_153 | COG | COG1488 | Nicotinic acid phosphoribosyltransferase | NA |
| UHGV-1497155_153 | Structural annotation | PF04095, PF17767, NF006629, COG1488 | NA | NA |
| UHGV-1497155_154 | KOfam | K15529 | POA1; ADP-ribose 1''-phosphate phosphatase [EC:3.1.3.84] | NA |
| UHGV-1497155_154 | PHROG | phrog_335 | phosphatase | other |
| UHGV-1497155_154 | UniRef90 | UniRef90_A0A416U272 | Macro domain-containing protein | NA |
| UHGV-1497155_154 | eggNOG-mapper | 1163671.JAGI01000002_gene1902 | Macro domain | NA |
| UHGV-1497155_154 | PADLOC | darG | NA | NA |
| UHGV-1497155_154 | Pfam | PF01661 | Macro domain | Macro |
| UHGV-1497155_154 | COG | COG2110 | O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain | NA |
| UHGV-1497155_154 | Structural annotation | PF20016, MF_01205, NF001666, COG2110 | NA | NA |
| UHGV-1497155_155 | KOfam | K01916 | nadE; NAD+ synthase [EC:6.3.1.5] | NA |
| UHGV-1497155_155 | PHROG | phrog_11189 | NAD synthetase | other |
| UHGV-1497155_155 | UniRef90 | UniRef90_R9JVR8 | NH(3)-dependent NAD(+) synthetase | NA |
| UHGV-1497155_155 | eggNOG-mapper | 397291.C804_00934 | NAD synthase | NA |
| UHGV-1497155_155 | Pfam | PF02540 | NAD synthase | NAD_synthase |
| UHGV-1497155_155 | NCBIFam | TIGR00552.1 | NAD(+) synthase | NA |
| UHGV-1497155_155 | COG | COG0171 | NH3-dependent NAD+ synthetase | NA |
| UHGV-1497155_155 | Structural annotation | PF02540, MF_02090, TIGR00552, COG0171 | NA | NA |
| UHGV-1497155_156 | PHROG | phrog_6365 | NA | unknown function |
| UHGV-1497155_157 | PHROG | phrog_9653 | NA | unknown function |
| UHGV-1497155_157 | UniRef90 | UniRef90_UPI001D12E223 | PcfJ domain-containing protein | NA |
| UHGV-1497155_157 | eggNOG-mapper | 397291.C804_00957 | PcfJ-like protein | NA |
| UHGV-1497155_157 | Pfam | PF14284 | PcfJ-like protein | PcfJ |
| UHGV-1497155_157 | Structural annotation | PF14284 | NA | NA |
| UHGV-1497155_158 | PHROG | phrog_9910 | NA | unknown function |
| UHGV-1497155_158 | Structural annotation | PF13973, COG4481 | NA | NA |
| UHGV-1497155_159 | Structural annotation | PF06034 | NA | NA |
| UHGV-1497155_160 | PHROG | phrog_9958 | NA | unknown function |
| UHGV-1497155_160 | UniRef90 | UniRef90_A0A4Q5C6P1 | NA | NA |
| UHGV-1497155_160 | eggNOG-mapper | 658655.HMPREF0988_00873 | NA | NA |
| UHGV-1497155_160 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-1497155_160 | Structural annotation | PF19789 | NA | NA |
| UHGV-1497155_164 | Structural annotation | PF16103 | NA | NA |
| UHGV-1497155_166 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-1497155_166 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-1497155_167 | Structural annotation | PF11195, PF09629, MF_00667, TIGR00405, COG4014 | NA | NA |
| UHGV-1497155_168 | UniRef90 | UniRef90_A0A417CMW1 | NA | NA |
| UHGV-1497155_168 | eggNOG-mapper | 742735.HMPREF9467_00878 | NA | NA |
| UHGV-1497155_171 | UniRef90 | UniRef90_UPI001C0F1354 | NA | NA |
| UHGV-1497155_171 | eggNOG-mapper | 1235802.C823_04740 | NA | NA |
| UHGV-1497155_171 | Pfam | PF19157 | NA | DUF5839 |
| UHGV-1497155_171 | Structural annotation | PF02195, PF19157, TIGR00180 | NA | NA |
| UHGV-1497155_172 | KOfam | K07074 | NA | NA |
| UHGV-1497155_172 | PHROG | phrog_388 | nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_172 | UniRef90 | UniRef90_UPI0004E1CEBE | nucleotidyltransferase domain-containing protein | NA |
| UHGV-1497155_172 | eggNOG-mapper | 1408311.JNJM01000020_gene3054 | Predicted nucleotidyltransferase | NA |
| UHGV-1497155_172 | Pfam | PF10127 | RNA repair pathway DNA polymerase beta family | RlaP |
| UHGV-1497155_172 | COG | COG3541 | Predicted nucleotidyltransferase YcgL | NA |
| UHGV-1497155_172 | Structural annotation | PF10127, NF000181, COG3541 | NA | NA |
| UHGV-1497155_173 | UniRef90 | UniRef90_A0A7D3QWD9 | R3H domain-containing protein | NA |
| UHGV-1497155_173 | eggNOG-mapper | 1235802.C823_04708 | NA | NA |
| UHGV-1497155_174 | KOfam | K00974 | cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] | NA |
| UHGV-1497155_174 | PHROG | phrog_2244 | tRNA nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_174 | UniRef90 | UniRef90_A0A414ZR40 | HD domain-containing protein | NA |
| UHGV-1497155_174 | eggNOG-mapper | 742735.HMPREF9467_00849 | NA | NA |
| UHGV-1497155_174 | Pfam | PF01743 | Poly A polymerase head domain | PolyA_pol |
| UHGV-1497155_174 | Pfam | PF12627 | Probable RNA and SrmB- binding site of polymerase A | PolyA_pol_RNAbd |
| UHGV-1497155_174 | Pfam | PF13735 | tRNA nucleotidyltransferase domain 2 putative | tRNA_NucTran2_2 |
| UHGV-1497155_174 | COG | COG0617 | tRNA nucleotidyltransferase/poly(A) polymerase | NA |
| UHGV-1497155_174 | Structural annotation | PF01743, PF13735, PF12627, MF_01263, TIGR02692, COG0617 | NA | NA |
| UHGV-1497155_175 | KOfam | K07097 | NA | NA |
| UHGV-1497155_175 | PHROG | phrog_4771 | DHH phosphoesterase | other |
| UHGV-1497155_175 | UniRef90 | UniRef90_N2A3U4 | DHHA1 domain-containing protein | NA |
| UHGV-1497155_175 | eggNOG-mapper | 397291.C804_00959 | hydrolase activity, acting on ester bonds | NA |
| UHGV-1497155_175 | COG | COG2404 | Oligoribonuclease NrnA/c-di-AMP phosphodiesterase DhhP, DHH superfamily | NA |
| UHGV-1497155_175 | Structural annotation | PF02272, MF_00207, NF040701, COG2404 | NA | NA |
| UHGV-1497155_177 | PHROG | phrog_2316 | NA | unknown function |
| UHGV-1497155_177 | UniRef90 | UniRef90_UPI00156FA052 | NA | NA |
| UHGV-1497155_177 | eggNOG-mapper | 1280676.AUJO01000024_gene3262 | NA | NA |
| UHGV-1497155_177 | Structural annotation | PF16475, MF_00436, NF033216, COG1923 | NA | NA |
| UHGV-1497155_178 | KOfam | K07496 | K07496; putative transposase | NA |
| UHGV-1497155_178 | PHROG | phrog_506 | transposase | integration and excision |
| UHGV-1497155_178 | UniRef90 | UniRef90_A0A415HV88 | Transposase | NA |
| UHGV-1497155_178 | eggNOG-mapper | 411470.RUMGNA_00042 | NA | NA |
| UHGV-1497155_178 | PADLOC | Cas14u | CAS-V-F; effector__SPE | CRISPR-CAS |
| UHGV-1497155_178 | Pfam | PF12323 | Helix-turn-helix domain | HTH_OrfB_IS605 |
| UHGV-1497155_178 | Pfam | PF01385 | Probable transposase | OrfB_IS605 |
| UHGV-1497155_178 | Pfam | PF07282 | Putative transposase DNA-binding domain | OrfB_Zn_ribbon |
| UHGV-1497155_178 | NCBIFam | NF038281.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | NA |
| UHGV-1497155_178 | COG | COG0675 | Transposase | NA |
| UHGV-1497155_178 | Structural annotation | PF07282, PF01385, NF038281, COG0675 | NA | NA |
| UHGV-1497155_179 | PHROG | phrog_850 | RNA-binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_179 | UniRef90 | UniRef90_UPI001897CACF | NA | NA |
| UHGV-1497155_179 | eggNOG-mapper | 397291.C804_02171 | NA | NA |
| UHGV-1497155_179 | Pfam | PF11443 | NA | DUF2828 |
| UHGV-1497155_179 | COG | COG2304 | Secreted protein containing bacterial Ig-like domain and vWFA domain | NA |
| UHGV-1497155_179 | Structural annotation | PF11443, MF_01340, COG2304 | NA | NA |
| UHGV-1497155_181 | PHROG | phrog_774 | NA | unknown function |
| UHGV-1497155_181 | eggNOG-mapper | 397290.C810_05225 | NA | NA |
| UHGV-1497155_182 | eggNOG-mapper | 1444310.JANV01000096_gene3236 | NA | NA |
| UHGV-1497155_182 | Structural annotation | NF004476 | NA | NA |
| UHGV-1497155_183 | PHROG | phrog_124 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_183 | UniRef90 | UniRef90_UPI001C037764 | AAA family ATPase | NA |
| UHGV-1497155_183 | eggNOG-mapper | 1274524.BSONL12_23125 | AAA domain | NA |
| UHGV-1497155_183 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-1497155_183 | Structural annotation | PF13479, MF_00268, TIGR01618, COG0468 | NA | NA |
| UHGV-1497155_184 | Structural annotation | PF01246, MF_00773, NF041023, COG2075 | NA | NA |
| UHGV-1497155_185 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-1497155_185 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_185 | UniRef90 | UniRef90_A0A415MEA4 | SF4 helicase domain-containing protein | NA |
| UHGV-1497155_185 | eggNOG-mapper | 1304866.K413DRAFT_4621 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-1497155_185 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-1497155_185 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-1497155_185 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-1497155_186 | PHROG | phrog_47 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_186 | UniRef90 | UniRef90_A0A2N5H4V4 | DNA primase | NA |
| UHGV-1497155_186 | eggNOG-mapper | 1304866.K413DRAFT_4620 | DNA primase activity | NA |
| UHGV-1497155_186 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-1497155_186 | Structural annotation | PF01807, PF19898, MF_00974, NF006382, COG0358 | NA | NA |
| UHGV-1497155_187 | KOfam | K07462 | recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] | NA |
| UHGV-1497155_187 | PHROG | phrog_2484 | RecJ-like ssDNA exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_187 | UniRef90 | UniRef90_A0A415MDW9 | DHH domain-containing protein | NA |
| UHGV-1497155_187 | eggNOG-mapper | 1304866.K413DRAFT_4619 | single-stranded DNA 5'-3' exodeoxyribonuclease activity | NA |
| UHGV-1497155_187 | Pfam | PF01368 | DHH family | DHH |
| UHGV-1497155_187 | Pfam | PF02272 | DHHA1 domain | DHHA1 |
| UHGV-1497155_187 | COG | COG0608 | ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation | NA |
| UHGV-1497155_187 | Structural annotation | PF17768, PF02272, MF_00984, MF_00068, TIGR00644, COG0608, COG3390 | NA | NA |
| UHGV-1497155_188 | KOfam | K02337 | dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] | NA |
| UHGV-1497155_188 | PHROG | phrog_405 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_188 | UniRef90 | UniRef90_A0A415ME36 | DNA-directed DNA polymerase | NA |
| UHGV-1497155_188 | eggNOG-mapper | 742733.HMPREF9469_00867 | DNA polymerase III alpha subunit | NA |
| UHGV-1497155_188 | Pfam | PF02811 | PHP domain | PHP |
| UHGV-1497155_188 | Pfam | PF07733 | Bacterial DNA polymerase III alpha NTPase domain | DNA_pol3_alpha |
| UHGV-1497155_188 | Pfam | PF17657 | Bacterial DNA polymerase III alpha subunit finger domain | DNA_pol3_finger |
| UHGV-1497155_188 | COG | COG0587 | DNA polymerase III, alpha subunit | NA |
| UHGV-1497155_188 | Structural annotation | PF07733, PF02811, PF17657, PF06075, PF14579, MF_01902, TIGR00594, COG0587 | NA | NA |
| UHGV-1497155_189 | PHROG | phrog_3490 | ERCC4-type nuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_189 | UniRef90 | UniRef90_A0A416U221 | ERCC4 domain-containing protein | NA |
| UHGV-1497155_189 | eggNOG-mapper | 1304866.K413DRAFT_4799 | ERCC4 domain | NA |
| UHGV-1497155_189 | Pfam | PF02732 | ERCC4 domain | ERCC4 |
| UHGV-1497155_189 | COG | COG1948 | ERCC4-type crossover junction endonuclease | NA |
| UHGV-1497155_189 | Structural annotation | PF02732, NF040956, COG1948 | NA | NA |
| UHGV-1497155_192 | PHROG | phrog_8077 | NA | unknown function |
| UHGV-1497155_192 | Structural annotation | PF16069 | NA | NA |
| UHGV-1497155_195 | Structural annotation | PF14947, COG3432 | NA | NA |
| UHGV-1497155_196 | Structural annotation | PF13069 | NA | NA |
| UHGV-1497155_198 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-1497155_198 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-1497155_198 | UniRef90 | UniRef90_UPI00164C8B32 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-1497155_198 | eggNOG-mapper | 1280688.AUJB01000008_gene903 | Clp protease | NA |
| UHGV-1497155_198 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-1497155_198 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-1497155_198 | Structural annotation | PF00574, MF_00444, NF011091, COG0740 | NA | NA |
| UHGV-1497155_200 | PHROG | phrog_6306 | NA | unknown function |
| UHGV-1497155_200 | eggNOG-mapper | 180332.JTGN01000008_gene4121 | NA | NA |
| UHGV-1497155_200 | Structural annotation | PF15585 | NA | NA |
| UHGV-1497155_203 | PHROG | phrog_5068 | NA | unknown function |
| UHGV-1497155_204 | PHROG | phrog_30343 | NA | unknown function |
| UHGV-1497155_204 | UniRef90 | UniRef90_A0A417A5J9 | N-acetyltransferase | NA |
| UHGV-1497155_204 | eggNOG-mapper | 397291.C804_00939 | NA | NA |
| UHGV-1497155_204 | Structural annotation | PF11039, MF_02210, TIGR03585, COG1670 | NA | NA |
| UHGV-1497155_208 | PHROG | phrog_1374 | NA | unknown function |
| UHGV-1497155_208 | UniRef90 | UniRef90_A0A482JLT4 | Putative membrane protein | NA |
| UHGV-1497155_208 | eggNOG-mapper | 445972.ANACOL_03351 | NA | NA |
| UHGV-1497155_208 | Structural annotation | TIGR04438 | NA | NA |
| UHGV-1497155_213 | Structural annotation | PF13983 | NA | NA |
| UHGV-1497155_216 | KOfam | K06223 | dam; DNA adenine methylase [EC:2.1.1.72] | NA |
| UHGV-1497155_216 | PHROG | phrog_56 | DNA methyltransferase | other |
| UHGV-1497155_216 | UniRef90 | UniRef90_A0A1C6AFL2 | Site-specific DNA-methyltransferase (adenine-specific) | NA |
| UHGV-1497155_216 | eggNOG-mapper | 1416012.V5URG0_9CAUD | D12 class N6 adenine-specific DNA methyltransferase | NA |
| UHGV-1497155_216 | PADLOC | MTase_II_00080 | Type II methyltransferase | RM |
| UHGV-1497155_216 | Pfam | PF02086 | D12 class N6 adenine-specific DNA methyltransferase | MethyltransfD12 |
| UHGV-1497155_216 | Structural annotation | PF02086, MF_01012, TIGR00571, COG0338 | NA | NA |
| UHGV-1497155_217 | Structural annotation | PF01424, MF_01302_B, COG0096 | NA | NA |
| UHGV-1497155_220 | UniRef90 | UniRef90_R7A361 | Predicted phosphoesterase or phosphohydrolase | NA |
| UHGV-1497155_222 | PHROG | phrog_21026 | NA | unknown function |
| UHGV-1497155_223 | Structural annotation | PF13783, MF_01888, NF008362, COG5515 | NA | NA |
| UHGV-1497155_224 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-1497155_224 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_224 | UniRef90 | UniRef90_A0A415ME28 | DNA ligase | NA |
| UHGV-1497155_224 | eggNOG-mapper | 1235802.C823_04644 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-1497155_224 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-1497155_224 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-1497155_224 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-1497155_224 | NCBIFam | NF005932.1 | NAD-dependent DNA ligase LigA | NA |
| UHGV-1497155_224 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1497155_224 | HAMAP | MF_01588 | DNA ligase [ligA] | NA |
| UHGV-1497155_224 | Structural annotation | PF01653, PF03120, PF00533, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-1497155_225 | UniRef90 | UniRef90_A0A1C6D809 | Bacterial SH3 domain | NA |
| UHGV-1497155_225 | eggNOG-mapper | 1408312.JNJS01000001_gene1349 | NA | NA |
| UHGV-1497155_226 | UniRef90 | UniRef90_D3T5D1 | HPr domain-containing protein | NA |
| UHGV-1497155_226 | eggNOG-mapper | 580331.Thit_0104 | PTS HPr component phosphorylation site | NA |
| UHGV-1497155_226 | COG | COG1925 | HPr or related phosphotransfer protein | NA |
| UHGV-1497155_226 | Structural annotation | PF00381, NF010354, COG1925 | NA | NA |
| UHGV-1497155_228 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-1497155_228 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-1497155_228 | UniRef90 | UniRef90_S2Y4V1 | Guanylate kinase-like domain-containing protein | NA |
| UHGV-1497155_228 | eggNOG-mapper | 742735.HMPREF9467_00910 | Guanylate kinase homologues. | NA |
| UHGV-1497155_228 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-1497155_228 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-1497155_228 | Structural annotation | PF00625, MF_00328, TIGR03263, COG0194 | NA | NA |
| UHGV-1497155_231 | UniRef90 | UniRef90_A0A7X9HH29 | Thioredoxin family protein | NA |
| UHGV-1497155_231 | Structural annotation | PF13192, MF_01132, TIGR02190, COG0695 | NA | NA |
| UHGV-1497155_232 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-1497155_232 | PHROG | phrog_25611 | anaerobic ribonucleoside reductase large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_232 | UniRef90 | UniRef90_A0A416P7M6 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-1497155_232 | eggNOG-mapper | 12336.Q332F0_CBCP | ribonucleoside-triphosphate reductase activity | NA |
| UHGV-1497155_232 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-1497155_232 | Structural annotation | PF13597, NF006127, COG1328 | NA | NA |
| UHGV-1497155_233 | PHROG | phrog_7168 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_233 | UniRef90 | UniRef90_A0A345BPZ8 | GIY-YIG domain-containing protein | NA |
| UHGV-1497155_233 | eggNOG-mapper | 1173135.I4DSI5_9CAUD | endonuclease activity | NA |
| UHGV-1497155_233 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-1497155_233 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-1497155_234 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-1497155_234 | PHROG | phrog_25611 | anaerobic ribonucleoside reductase large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_234 | UniRef90 | UniRef90_A0A8D9PE47 | Anaerobic ribonucleoside triphosphate reductase | NA |
| UHGV-1497155_234 | eggNOG-mapper | 771875.Ferpe_1491 | TIGRFAM Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-1497155_234 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-1497155_234 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-1497155_235 | KOfam | K04068 | nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] | NA |
| UHGV-1497155_235 | PHROG | phrog_626 | anaerobic ribonucleotide reductase small subunit | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_235 | UniRef90 | UniRef90_A0A843GN71 | 4Fe-4S cluster-binding domain-containing protein | NA |
| UHGV-1497155_235 | eggNOG-mapper | 195103.CPF_0923 | 4Fe-4S single cluster domain | NA |
| UHGV-1497155_235 | Pfam | PF13353 | 4Fe-4S single cluster domain | Fer4_12 |
| UHGV-1497155_235 | COG | COG0602 | Organic radical activating enzyme NrdG/QueE | NA |
| UHGV-1497155_235 | Structural annotation | PF13353, MF_00917, TIGR02491, COG0602 | NA | NA |
| UHGV-1497155_236 | PHROG | phrog_38239 | NA | unknown function |
| UHGV-1497155_236 | UniRef90 | UniRef90_A0A416PEI7 | Ferredoxin:thioredoxin reductase | NA |
| UHGV-1497155_236 | eggNOG-mapper | 1410617.JHXH01000005_gene1074 | Ferredoxin thioredoxin reductase catalytic beta chain | NA |
| UHGV-1497155_236 | Pfam | PF02943 | Ferredoxin thioredoxin reductase catalytic beta chain | FeThRed_B |
| UHGV-1497155_236 | Structural annotation | NF041072, COG4802 | NA | NA |
| UHGV-1497155_239 | eggNOG-mapper | 411470.RUMGNA_00009 | NA | NA |
| UHGV-1497155_239 | Structural annotation | PF18358, NF037951, COG4481 | NA | NA |
| UHGV-1497155_242 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-1497155_242 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_242 | UniRef90 | UniRef90_UPI00164BF701 | dUTP diphosphatase | NA |
| UHGV-1497155_242 | eggNOG-mapper | 1408436.JHXY01000007_gene317 | This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | NA |
| UHGV-1497155_242 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-1497155_242 | NCBIFam | TIGR00576.1 | dUTP diphosphatase | NA |
| UHGV-1497155_242 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-1497155_242 | Structural annotation | PF00692, MF_00116, TIGR00576, COG0756 | NA | NA |
| UHGV-1497155_243 | UniRef90 | UniRef90_A0A1C5WQU8 | DNA binding domain, excisionase family | NA |
| UHGV-1497155_243 | eggNOG-mapper | 1256908.HMPREF0373_02050 | excisionase family | NA |
| UHGV-1497155_243 | Pfam | PF12728 | Helix-turn-helix domain | HTH_17 |
| UHGV-1497155_243 | NCBIFam | TIGR01764.1 | excisionase family DNA-binding protein | NA |
| UHGV-1497155_244 | KOfam | K14059 | int; integrase | NA |
| UHGV-1497155_244 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1497155_244 | UniRef90 | UniRef90_U2R858 | Site-specific recombinase, phage integrase family | NA |
| UHGV-1497155_244 | eggNOG-mapper | 1256908.HMPREF0373_01612 | Phage integrase family | NA |
| UHGV-1497155_244 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1497155_244 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1497155_244 | Structural annotation | PF00589, MF_01808, NF007246, COG4974 | NA | NA |
| UHGV-1497155_245 | PHROG | phrog_1934 | NA | unknown function |
| UHGV-1497155_245 | UniRef90 | UniRef90_UPI001D08EB34 | NA | NA |
| UHGV-1497155_245 | eggNOG-mapper | 1378168.N510_01429 | zinc-finger-containing domain | NA |
| UHGV-1497155_245 | Pfam | PF11672 | zinc-finger-containing domain | DUF3268 |
| UHGV-1497155_245 | Structural annotation | PF11672 | NA | NA |
| UHGV-1497155_246 | KOfam | K03091 | sigH; RNA polymerase sporulation-specific sigma factor | NA |
| UHGV-1497155_246 | UniRef90 | UniRef90_U2PA96 | Sigma-70 region 2 | NA |
| UHGV-1497155_246 | Pfam | PF04542 | Sigma-70 region 2 | Sigma70_r2 |
| UHGV-1497155_246 | NCBIFam | TIGR02937.1 | sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-1497155_246 | COG | COG1191 | DNA-directed RNA polymerase specialized sigma subunit | NA |
| UHGV-1497155_248 | KOfam | K03087 | rpoS; RNA polymerase nonessential primary-like sigma factor | NA |
| UHGV-1497155_248 | PHROG | phrog_351 | RNA polymerase sigma factor | transcription regulation |
| UHGV-1497155_248 | UniRef90 | UniRef90_A0A2V1JQM8 | Sigma70_r2 domain-containing protein | NA |
| UHGV-1497155_248 | eggNOG-mapper | 1256908.HMPREF0373_03325 | sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released | NA |
| UHGV-1497155_248 | PADLOC | MzaA_00001 | NA | mzaABCDE |
| UHGV-1497155_248 | Pfam | PF04542 | Sigma-70 region 2 | Sigma70_r2 |
| UHGV-1497155_248 | Pfam | PF13412 | Winged helix-turn-helix DNA-binding | HTH_24 |
| UHGV-1497155_248 | NCBIFam | TIGR02937.1 | sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-1497155_248 | COG | COG0568 | DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) | NA |
| UHGV-1497155_248 | Structural annotation | PF04542, PF04539, MF_00959, NF005920, COG0568 | NA | NA |
| UHGV-1497155_253 | PHROG | phrog_674 | NA | unknown function |
| UHGV-1497155_253 | UniRef90 | UniRef90_A0A3R6XKZ4 | NA | NA |
| UHGV-1497155_253 | eggNOG-mapper | 1256908.HMPREF0373_03330 | NA | NA |
| UHGV-1497155_253 | Pfam | PF07083 | NA | DUF1351 |
| UHGV-1497155_254 | PHROG | phrog_47 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_254 | UniRef90 | UniRef90_A0A3A9BMB2 | DNA primase | NA |
| UHGV-1497155_254 | eggNOG-mapper | 1256908.HMPREF0373_03331 | NA | NA |
| UHGV-1497155_254 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-1497155_255 | KOfam | K03581 | recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] | NA |
| UHGV-1497155_255 | PHROG | phrog_4412 | exonuclease V | DNA, RNA and nucleotide metabolism |
| UHGV-1497155_255 | UniRef90 | UniRef90_UPI001A9A55EB | AAA family ATPase | NA |
| UHGV-1497155_255 | eggNOG-mapper | 1256908.HMPREF0373_03332 | DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity | NA |
| UHGV-1497155_255 | PADLOC | cluster10 | RecD_0_IVD | CRISPR-CAS |
| UHGV-1497155_255 | Pfam | PF14490 | Helix-hairpin-helix containing domain | HHH_4 |
| UHGV-1497155_255 | Pfam | PF13245 | AAA domain | AAA_19 |
| UHGV-1497155_255 | Pfam | PF18335 | ATP-dependent RecD-like DNA helicase SH3 domain | SH3_13 |
| UHGV-1497155_255 | Pfam | PF13538 | UvrD-like helicase C-terminal domain | UvrD_C_2 |
| UHGV-1497155_255 | NCBIFam | TIGR01448.1 | ATP-dependent RecD-like DNA helicase | NA |
| UHGV-1497155_255 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-1497155_255 | Structural annotation | PF13604, PF14490, PF18335, PF01336, MF_01488, TIGR01448, COG0507 | NA | NA |
| UHGV-1497155_256 | KOfam | K07459 | ybjD; putative ATP-dependent endonuclease of the OLD family | NA |
| UHGV-1497155_256 | PHROG | phrog_13167 | NA | unknown function |
| UHGV-1497155_256 | UniRef90 | UniRef90_A0A414IBW6 | ATP-binding protein | NA |
| UHGV-1497155_256 | eggNOG-mapper | 1256908.HMPREF0373_03333 | AAA ATPase domain | NA |
| UHGV-1497155_256 | PADLOC | AAA_15 | NA | NA |
| UHGV-1497155_256 | Pfam | PF13175 | AAA ATPase domain | AAA_15 |
| UHGV-1497155_256 | COG | COG4637 | Predicted ATPase | NA |
| UHGV-1497155_256 | Structural annotation | PF11398, MF_00365, NF041760, COG4938 | NA | NA |
| UHGV-1497155_257 | eggNOG-mapper | 1254432.SCE1572_51860 | NA | NA |
| UHGV-1497155_258 | eggNOG-mapper | 1256908.HMPREF0373_03335 | NA | NA |
| UHGV-1497155_259 | eggNOG-mapper | 1256908.HMPREF0373_03336 | NA | NA |
| UHGV-1497155_260 | eggNOG-mapper | 1256908.HMPREF0373_03337 | NA | NA |
| UHGV-1497155_261 | UniRef90 | UniRef90_A0A173QW65 | SMI1_KNR4 domain-containing protein | NA |
| UHGV-1497155_261 | eggNOG-mapper | 1256908.HMPREF0373_03338 | SMI1 / KNR4 family | NA |
| UHGV-1497155_261 | Pfam | PF09346 | SMI1 / KNR4 family (SUKH-1) | SMI1_KNR4 |
| UHGV-1497155_262 | KOfam | K21488 | yobK; antitoxin YobK | NA |
| UHGV-1497155_262 | PHROG | phrog_25414 | NA | unknown function |
| UHGV-1497155_262 | UniRef90 | UniRef90_R5TPA4 | SMI1 / KNR4 family | NA |
| UHGV-1497155_262 | eggNOG-mapper | 1256908.HMPREF0373_03339 | SMI1 KNR4 family | NA |
| UHGV-1497155_262 | Pfam | PF14567 | SMI1-KNR4 cell-wall | SUKH_5 |
| UHGV-1497155_264 | eggNOG-mapper | 1256908.HMPREF0373_03342 | NA | NA |
| UHGV-1497155_265 | eggNOG-mapper | 1256908.HMPREF0373_03343 | NA | NA |