| UHGV-1497503_2 | KOfam | K14059 | int; integrase | NA |
| UHGV-1497503_2 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1497503_2 | UniRef90 | UniRef90_UPI001D155F20 | tyrosine-type recombinase/integrase | NA |
| UHGV-1497503_2 | eggNOG-mapper | 1095750.HMPREF9970_1688 | Phage integrase, N-terminal SAM-like domain | NA |
| UHGV-1497503_2 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1497503_2 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1497503_2 | Structural annotation | PF00589, PF12167, MF_02055, NF040815, COG4974 | NA | NA |
| UHGV-1497503_3 | PHROG | phrog_9418 | NA | unknown function |
| UHGV-1497503_3 | eggNOG-mapper | 411462.DORLON_00822 | NA | NA |
| UHGV-1497503_3 | Structural annotation | PF10233 | NA | NA |
| UHGV-1497503_4 | UniRef90 | UniRef90_A0A3E2U3W7 | NA | NA |
| UHGV-1497503_4 | eggNOG-mapper | 742740.HMPREF9474_04329 | NA | NA |
| UHGV-1497503_5 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-1497503_5 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-1497503_5 | UniRef90 | UniRef90_R6JX71 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1497503_5 | eggNOG-mapper | 411473.RUMCAL_03095 | NA | NA |
| UHGV-1497503_5 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-1497503_5 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-1497503_5 | Structural annotation | PF00717, PF01381, MF_00015, TIGR00498, COG1974 | NA | NA |
| UHGV-1497503_6 | Structural annotation | PF20385 | NA | NA |
| UHGV-1497503_7 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1497503_7 | UniRef90 | UniRef90_A0A3E2U419 | XRE family transcriptional regulator | NA |
| UHGV-1497503_7 | eggNOG-mapper | 1229517.AMFD01000025_gene921 | Lactococcus bacteriophage repressor | NA |
| UHGV-1497503_7 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1497503_7 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1497503_7 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-1497503_11 | PHROG | phrog_4433 | NA | unknown function |
| UHGV-1497503_11 | eggNOG-mapper | 645991.Sgly_0315 | regulation of DNA-templated transcription, elongation | NA |
| UHGV-1497503_11 | COG | COG5164 | Transcription elongation factor SPT5 | NA |
| UHGV-1497503_11 | Structural annotation | NF007410 | NA | NA |
| UHGV-1497503_12 | AcrCatalog | cluster_17974 | NA | NA |
| UHGV-1497503_20 | PHROG | phrog_7838 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1497503_20 | UniRef90 | UniRef90_A0A8D9UGW3 | DNA repair protein RAD52-like protein | NA |
| UHGV-1497503_20 | eggNOG-mapper | 742767.HMPREF9456_02052 | NA | NA |
| UHGV-1497503_20 | Structural annotation | PF04098, TIGR00607, COG4380 | NA | NA |
| UHGV-1497503_21 | PHROG | phrog_398 | NA | unknown function |
| UHGV-1497503_21 | UniRef90 | UniRef90_UPI0011780B2F | putative HNHc nuclease | NA |
| UHGV-1497503_21 | eggNOG-mapper | 33035.JPJF01000122_gene2462 | Putative HNHc nuclease | NA |
| UHGV-1497503_21 | Pfam | PF16784 | Putative HNHc nuclease | HNHc_6 |
| UHGV-1497503_21 | Structural annotation | PF16784 | NA | NA |
| UHGV-1497503_22 | eggNOG-mapper | 1304866.K413DRAFT_4636 | NA | NA |
| UHGV-1497503_22 | Structural annotation | PF17457 | NA | NA |
| UHGV-1497503_23 | PHROG | phrog_2113 | NA | unknown function |
| UHGV-1497503_23 | eggNOG-mapper | 1160721.RBI_II00485 | NA | NA |
| UHGV-1497503_23 | Structural annotation | PF21715, TIGR04176, COG1654 | NA | NA |
| UHGV-1497503_24 | PHROG | phrog_244 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1497503_24 | eggNOG-mapper | 742740.HMPREF9474_03491 | NA | NA |
| UHGV-1497503_24 | Structural annotation | PF01870, MF_01490, NF040854, COG1591 | NA | NA |
| UHGV-1497503_25 | PHROG | phrog_15768 | NA | unknown function |
| UHGV-1497503_25 | UniRef90 | UniRef90_UPI001C00EC79 | NA | NA |
| UHGV-1497503_25 | eggNOG-mapper | 33035.JPJF01000122_gene2459 | NA | NA |
| UHGV-1497503_25 | AcrCatalog | cluster_14472 | NA | NA |
| UHGV-1497503_25 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-1497503_25 | Structural annotation | PF19808 | NA | NA |
| UHGV-1497503_27 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1497503_27 | PHROG | phrog_363 | DNA methyltransferase | other |
| UHGV-1497503_27 | UniRef90 | UniRef90_UPI001EE0657A | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1497503_27 | eggNOG-mapper | 742738.HMPREF9460_04053 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1497503_27 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-1497503_27 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1497503_27 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1497503_27 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1497503_27 | Structural annotation | PF00145, MF_00351, TIGR00675, COG0270 | NA | NA |
| UHGV-1497503_28 | PHROG | phrog_874 | NA | unknown function |
| UHGV-1497503_28 | UniRef90 | UniRef90_A0A6N7W7Q7 | ASCH domain-containing protein | NA |
| UHGV-1497503_28 | eggNOG-mapper | 411468.CLOSCI_00298 | NA | NA |
| UHGV-1497503_28 | Structural annotation | PF04266, MF_00684, NF003443, COG4043 | NA | NA |
| UHGV-1497503_30 | KOfam | K03798 | ftsH, hflB; cell division protease FtsH [EC:3.4.24.-] | NA |
| UHGV-1497503_30 | PHROG | phrog_3757 | NA | unknown function |
| UHGV-1497503_30 | UniRef90 | UniRef90_UPI0004838306 | ATP-binding protein | NA |
| UHGV-1497503_30 | eggNOG-mapper | 1235802.C823_01035 | ATPase family associated with various cellular activities (AAA) | NA |
| UHGV-1497503_30 | PADLOC | IetA_00002 | NA | ietAS |
| UHGV-1497503_30 | Pfam | PF00004 | ATPase family associated with various cellular activities (AAA) | AAA |
| UHGV-1497503_30 | COG | COG0464 | AAA+-type ATPase, SpoVK/Ycf46/Vps4 family | NA |
| UHGV-1497503_30 | Structural annotation | PF00004, MF_00553, TIGR01242, COG1222 | NA | NA |
| UHGV-1497503_33 | AcrCatalog | cluster_180719 | NA | NA |
| UHGV-1497503_34 | PHROG | phrog_2428 | NA | unknown function |
| UHGV-1497503_34 | UniRef90 | UniRef90_UPI0013F5FCC5 | ABC transporter ATPase | NA |
| UHGV-1497503_34 | eggNOG-mapper | 1415774.U728_1088 | NA | NA |
| UHGV-1497503_34 | dbAPIS | APIS024 | Tad1 proteins are not an enzymes, but are 'sponges' that bind and sequester the immune signaling molecule (cyclic ADP-ribose or gcADPR) produced by TIR-domain proteins, thus decoupling phage sensing from immune effector activation and rendering Thoeris inactive. | NA |
| UHGV-1497503_35 | UniRef90 | UniRef90_A0A3R6V2Q9 | CopG family transcriptional regulator | NA |
| UHGV-1497503_35 | Structural annotation | PF01402, NF041793, COG4710 | NA | NA |
| UHGV-1497503_36 | KOfam | K04763 | xerD; integrase/recombinase XerD | NA |
| UHGV-1497503_36 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1497503_36 | UniRef90 | UniRef90_C0CSR1 | Site-specific recombinase, phage integrase family | NA |
| UHGV-1497503_36 | eggNOG-mapper | 1298920.KI911353_gene2699 | Belongs to the 'phage' integrase family | NA |
| UHGV-1497503_36 | Pfam | PF13495 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_4 |
| UHGV-1497503_36 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1497503_36 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-1497503_36 | Structural annotation | PF00589, PF02899, MF_01807, TIGR02224, COG4973 | NA | NA |
| UHGV-1497503_37 | eggNOG-mapper | 476272.RUMHYD_01751 | NA | NA |
| UHGV-1497503_37 | AcrCatalog | cluster_11670 | NA | NA |
| UHGV-1497503_39 | KOfam | K19117 | csd1, cas8c; CRISPR-associated protein Csd1 | NA |
| UHGV-1497503_39 | UniRef90 | UniRef90_UPI0013F68F1D | type I-C CRISPR-associated protein Cas8c/Csd1 | NA |
| UHGV-1497503_39 | eggNOG-mapper | 1232428.CAVO010000037_gene1240 | CRISPR-associated protein, Csd1 family | NA |
| UHGV-1497503_39 | PADLOC | cd09757 | CAS-I-C; effector_LS | CRISPR-CAS |
| UHGV-1497503_39 | Pfam | PF09709 | CRISPR-associated protein (Cas_Csd1) | Cas_Csd1 |
| UHGV-1497503_39 | COG | COG5632 | N-acetylmuramoyl-L-alanine amidase CwlA | NA |
| UHGV-1497503_39 | Structural annotation | PF09709, TIGR01863 | NA | NA |
| UHGV-1497503_40 | AcrCatalog | cluster_39973 | NA | NA |
| UHGV-1497503_41 | PHROG | phrog_33130 | NA | unknown function |
| UHGV-1497503_42 | PHROG | phrog_606 | terminase small subunit | head and packaging |
| UHGV-1497503_42 | UniRef90 | UniRef90_UPI001F487344 | DNA-packaging protein | NA |
| UHGV-1497503_42 | eggNOG-mapper | 397290.C810_05185 | DNA-packaging protein gp3 | NA |
| UHGV-1497503_42 | Pfam | PF16677 | DNA-packaging protein gp3 | GP3_package |
| UHGV-1497503_42 | Structural annotation | PF16677 | NA | NA |
| UHGV-1497503_43 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-1497503_43 | PHROG | phrog_10250 | NA | unknown function |
| UHGV-1497503_43 | UniRef90 | UniRef90_A0A417Q599 | PBSX family phage terminase large subunit | NA |
| UHGV-1497503_43 | eggNOG-mapper | 476272.RUMHYD_01756 | NA | NA |
| UHGV-1497503_43 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-1497503_43 | Pfam | PF17288 | Terminase RNAseH like domain | Terminase_3C |
| UHGV-1497503_43 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-1497503_43 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-1497503_43 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1497503_44 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-1497503_44 | UniRef90 | UniRef90_A0A173R9C0 | Phage portal protein, putative, A118 family | NA |
| UHGV-1497503_44 | eggNOG-mapper | 476272.RUMHYD_01758 | phage minor capsid protein | NA |
| UHGV-1497503_44 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-1497503_45 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-1497503_45 | UniRef90 | UniRef90_A0A1C6CDG2 | Phage minor capsid protein 2 | NA |
| UHGV-1497503_45 | eggNOG-mapper | 33035.JPJF01000106_gene3134 | Phage minor capsid protein 2 | NA |
| UHGV-1497503_45 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-1497503_45 | COG | COG2369 | NA | NA |
| UHGV-1497503_45 | Structural annotation | PF06152 | NA | NA |
| UHGV-1497503_46 | PHROG | phrog_3754 | NA | unknown function |
| UHGV-1497503_46 | eggNOG-mapper | 476272.RUMHYD_01764 | NA | NA |
| UHGV-1497503_47 | UniRef90 | UniRef90_A0A417UWY7 | CTP synthase | NA |
| UHGV-1497503_47 | eggNOG-mapper | 411490.ANACAC_00705 | NA | NA |
| UHGV-1497503_48 | UniRef90 | UniRef90_A0A843HPX3 | Sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-1497503_48 | eggNOG-mapper | 1235790.C805_00057 | NA | NA |
| UHGV-1497503_48 | Structural annotation | PF13404, TIGR01636 | NA | NA |
| UHGV-1497503_49 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-1497503_49 | eggNOG-mapper | 476272.RUMHYD_01768 | NA | NA |