| UHGV-1954134_1 | PHROG | phrog_144 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_1 | UniRef90 | UniRef90_UPI0018AB3F33 | HNH endonuclease | NA |
| UHGV-1954134_1 | eggNOG-mapper | 536232.CLM_2937 | HNH nucleases | NA |
| UHGV-1954134_2 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-1954134_2 | UniRef90 | UniRef90_R5X6Q8 | Possible sigma factor | NA |
| UHGV-1954134_2 | eggNOG-mapper | 272562.CA_C0550 | sigma factor activity | NA |
| UHGV-1954134_2 | Pfam | PF08281 | Sigma-70, region 4 | Sigma70_r4_2 |
| UHGV-1954134_2 | COG | COG1191 | DNA-directed RNA polymerase specialized sigma subunit | NA |
| UHGV-1954134_2 | Structural annotation | PF08281, MF_00245, TIGR01636, COG1595 | NA | NA |
| UHGV-1954134_3 | KOfam | K06919 | K06919; putative DNA primase/helicase | NA |
| UHGV-1954134_3 | PHROG | phrog_864 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_3 | UniRef90 | UniRef90_A0A1C6GV86 | Phage/plasmid primase, P4 family, C-terminal domain | NA |
| UHGV-1954134_3 | eggNOG-mapper | 1304284.L21TH_2612 | TIGRFAM phage plasmid primase, P4 family, C-terminal domain | NA |
| UHGV-1954134_3 | Pfam | PF08706 | D5 N terminal like | D5_N |
| UHGV-1954134_3 | Pfam | PF19263 | NA | DUF5906 |
| UHGV-1954134_3 | Pfam | PF03288 | Poxvirus D5 protein-like | Pox_D5 |
| UHGV-1954134_3 | NCBIFam | TIGR01613.1 | phage/plasmid primase, P4 family | NA |
| UHGV-1954134_3 | COG | COG3378 | DNA primase, phage- or plasmid-associated | NA |
| UHGV-1954134_3 | Structural annotation | PF19263, PF08706, PF03288, PF09250, MF_04000, TIGR01613, COG3378 | NA | NA |
| UHGV-1954134_5 | PHROG | phrog_374 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_5 | UniRef90 | UniRef90_UPI0011060369 | helix-turn-helix domain-containing protein | NA |
| UHGV-1954134_5 | eggNOG-mapper | 357276.EL88_11255 | NA | NA |
| UHGV-1954134_5 | Structural annotation | PF02796, TIGR04381, COG2771 | NA | NA |
| UHGV-1954134_6 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-1954134_6 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_6 | UniRef90 | UniRef90_B6G0A3 | Flavin-dependent thymidylate synthase | NA |
| UHGV-1954134_6 | eggNOG-mapper | 500633.CLOHIR_01559 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant | NA |
| UHGV-1954134_6 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-1954134_6 | NCBIFam | TIGR02170.1 | FAD-dependent thymidylate synthase | NA |
| UHGV-1954134_6 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-1954134_6 | HAMAP | MF_01408 | Flavin-dependent thymidylate synthase [thyX] | NA |
| UHGV-1954134_6 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-1954134_9 | PHROG | phrog_236 | nucleotide kinase | other |
| UHGV-1954134_9 | UniRef90 | UniRef90_A0A413EEF9 | NA | NA |
| UHGV-1954134_9 | eggNOG-mapper | 673376.F2VHW0_9CAUD | NA | NA |
| UHGV-1954134_9 | Pfam | PF11753 | NA | DUF3310 |
| UHGV-1954134_10 | KOfam | K02319 | pol; DNA polymerase, archaea type [EC:2.7.7.7] | NA |
| UHGV-1954134_10 | PHROG | phrog_1252 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_10 | UniRef90 | UniRef90_A0A1C6GWY9 | DNA polymerase family B | NA |
| UHGV-1954134_10 | eggNOG-mapper | 445335.CBN_1360 | DNA polymerase elongation subunit (Family B) | NA |
| UHGV-1954134_10 | COG | COG0417 | DNA polymerase B elongation subunit | NA |
| UHGV-1954134_10 | Structural annotation | PF08490, MF_04100, TIGR00592, COG0417 | NA | NA |
| UHGV-1954134_11 | PHROG | phrog_7778 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_11 | UniRef90 | UniRef90_UPI0014751738 | NA | NA |
| UHGV-1954134_11 | eggNOG-mapper | 1123288.SOV_6c01550 | NA | NA |
| UHGV-1954134_11 | Pfam | PF05037 | NA | DUF669 |
| UHGV-1954134_11 | Structural annotation | PF05037 | NA | NA |
| UHGV-1954134_12 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_12 | UniRef90 | UniRef90_UPI001BABF1B9 | ERF family protein | NA |
| UHGV-1954134_12 | eggNOG-mapper | 929506.CbC4_1193 | ERF superfamily | NA |
| UHGV-1954134_12 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-1954134_13 | PHROG | phrog_9298 | radical SAM domain protein | other |
| UHGV-1954134_13 | UniRef90 | UniRef90_A0A498R1D5 | Radical sam alpha/beta horseshoe | NA |
| UHGV-1954134_13 | eggNOG-mapper | 1391646.AVSU01000016_gene3188 | NA | NA |
| UHGV-1954134_13 | COG | COG1032 | Radical SAM superfamily enzyme YgiQ, UPF0313 family | NA |
| UHGV-1954134_13 | Structural annotation | MF_01865, NF038361, COG0621 | NA | NA |
| UHGV-1954134_14 | PHROG | phrog_93 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_14 | UniRef90 | UniRef90_A0A1C6GW81 | VRR-NUC domain | NA |
| UHGV-1954134_14 | eggNOG-mapper | 203119.Cthe_1738 | VRR_NUC | NA |
| UHGV-1954134_14 | COG | COG1591 | Holliday junction resolvase Hjc, archaeal type | NA |
| UHGV-1954134_14 | Structural annotation | PF01870, MF_01490, NF040854, COG1591 | NA | NA |
| UHGV-1954134_15 | PHROG | phrog_6244 | NA | unknown function |
| UHGV-1954134_15 | UniRef90 | UniRef90_UPI0006C34CBC | siphovirus Gp157 family protein | NA |
| UHGV-1954134_15 | eggNOG-mapper | 1430331.EP10_02380 | YqaJ viral recombinase family | NA |
| UHGV-1954134_15 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-1954134_15 | Structural annotation | PF05565 | NA | NA |
| UHGV-1954134_16 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-1954134_16 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_16 | UniRef90 | UniRef90_A0A1C6GWE5 | ATP-dependent helicase HepA | NA |
| UHGV-1954134_16 | eggNOG-mapper | 1280692.AUJL01000009_gene2982 | snf2 family | NA |
| UHGV-1954134_16 | PADLOC | DpdE_00006 | DpdE | DPD |
| UHGV-1954134_16 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-1954134_16 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-1954134_16 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-1954134_16 | Structural annotation | PF16203, MF_01821, NF038318, COG0553 | NA | NA |
| UHGV-1954134_18 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-1954134_18 | PHROG | phrog_2967 | transcriptional regulator | transcription regulation |
| UHGV-1954134_18 | UniRef90 | UniRef90_A0A446IBV6 | XRE family transcriptional regulator | NA |
| UHGV-1954134_18 | eggNOG-mapper | 999411.HMPREF1092_03286 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-1954134_18 | Pfam | PF12844 | Helix-turn-helix domain | HTH_19 |
| UHGV-1954134_18 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1954134_18 | Structural annotation | PF01381, MF_00535, NF007257, COG1476 | NA | NA |
| UHGV-1954134_22 | KOfam | K18640 | parM, stbA; plasmid segregation protein ParM | NA |
| UHGV-1954134_22 | PHROG | phrog_691 | partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_22 | UniRef90 | UniRef90_UPI0005DE0931 | ParM/StbA family protein | NA |
| UHGV-1954134_22 | eggNOG-mapper | 536233.CLO_0569 | cell division | NA |
| UHGV-1954134_22 | Pfam | PF17989 | Actin like proteins N terminal domain | ALP_N |
| UHGV-1954134_22 | COG | COG0849 | Cell division ATPase FtsA | NA |
| UHGV-1954134_22 | Structural annotation | PF06723, MF_02207, NF010498, COG1077 | NA | NA |
| UHGV-1954134_25 | PHROG | phrog_186 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-1954134_25 | UniRef90 | UniRef90_UPI0018A9C559 | DnaD domain protein | NA |
| UHGV-1954134_25 | eggNOG-mapper | 985762.SAGN_05960 | NA | NA |
| UHGV-1954134_25 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-1954134_25 | Structural annotation | PF13730, NF040939, COG5625 | NA | NA |
| UHGV-1954134_28 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-1954134_28 | PHROG | phrog_3088 | amidase | lysis |
| UHGV-1954134_28 | UniRef90 | UniRef90_A0A7X9B8R6 | SH3 domain-containing protein | NA |
| UHGV-1954134_28 | eggNOG-mapper | 1396.DJ87_1663 | n-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1954134_28 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-1954134_28 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-1954134_28 | COG | COG5632 | N-acetylmuramoyl-L-alanine amidase CwlA | NA |
| UHGV-1954134_28 | Structural annotation | PF01510, PF18342, NF008758, NF033202, COG5632 | NA | NA |
| UHGV-1954134_29 | KOfam | K05996 | cpt; carboxypeptidase T [EC:3.4.17.18] | NA |
| UHGV-1954134_29 | PHROG | phrog_4722 | zinc carboxypeptidase | other |
| UHGV-1954134_29 | UniRef90 | UniRef90_UPI00112D5B96 | M14 family metallopeptidase | NA |
| UHGV-1954134_29 | eggNOG-mapper | 1406786.U5PVX3_9CAUD | metallocarboxypeptidase activity | NA |
| UHGV-1954134_29 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-1954134_29 | Pfam | PF00246 | Zinc carboxypeptidase | Peptidase_M14 |
| UHGV-1954134_30 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-1954134_30 | Pfam | PF13229 | Right handed beta helix region | Beta_helix |
| UHGV-1954134_30 | COG | COG2755 | Lysophospholipase L1 or related esterase. Includes spore coat protein LipC/YcsK | NA |
| UHGV-1954134_31 | PHROG | phrog_1067 | minor head protein | head and packaging |
| UHGV-1954134_31 | UniRef90 | UniRef90_UPI00164A835E | phage tail protein | NA |
| UHGV-1954134_31 | eggNOG-mapper | 999411.HMPREF1092_03309 | Prophage endopeptidase tail | NA |
| UHGV-1954134_31 | Pfam | PF06605 | Prophage endopeptidase tail | Prophage_tail |
| UHGV-1954134_31 | NCBIFam | TIGR01665.1 | phage tail spike protein | NA |
| UHGV-1954134_31 | COG | COG4926 | Phage-related protein | NA |
| UHGV-1954134_31 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-1954134_32 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-1954134_32 | UniRef90 | UniRef90_A0A1C6DMK9 | Phage-related protein | NA |
| UHGV-1954134_32 | eggNOG-mapper | 439292.Bsel_0802 | tail component | NA |
| UHGV-1954134_32 | NCBIFam | TIGR01633.1 | distal tail protein Dit | NA |
| UHGV-1954134_32 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-1954134_32 | Structural annotation | PF20195, TIGR01633, COG4722 | NA | NA |
| UHGV-1954134_33 | KOfam | K06674 | SMC2; structural maintenance of chromosome 2 | NA |
| UHGV-1954134_33 | PHROG | phrog_4704 | tail length tape measure protein | tail |
| UHGV-1954134_33 | UniRef90 | UniRef90_A0A6B4SLJ1 | Phage tail tape measure protein (Fragment) | NA |
| UHGV-1954134_33 | eggNOG-mapper | 411490.ANACAC_00728 | Phage tail tape measure protein, TP901 family | NA |
| UHGV-1954134_33 | Pfam | PF00261 | Tropomyosin | Tropomyosin |
| UHGV-1954134_33 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-1954134_33 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-1954134_33 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1954134_33 | Structural annotation | PF10145, PF05384, TIGR01760, TIGR02559, COG5280 | NA | NA |
| UHGV-1954134_34 | eggNOG-mapper | 536233.CLO_1369 | NA | NA |
| UHGV-1954134_34 | Structural annotation | PF11836 | NA | NA |
| UHGV-1954134_35 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-1954134_35 | eggNOG-mapper | 1414720.CBYM010000049_gene117 | phage major tail protein, phi13 family | NA |
| UHGV-1954134_35 | NCBIFam | TIGR01603.1 | major tail protein | NA |
| UHGV-1954134_35 | Structural annotation | PF04630, TIGR01603, COG3498 | NA | NA |
| UHGV-1954134_36 | eggNOG-mapper | 632245.CLP_2690 | NA | NA |
| UHGV-1954134_36 | Structural annotation | PF05657 | NA | NA |
| UHGV-1954134_37 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-1954134_37 | UniRef90 | UniRef90_UPI0018AAD4F8 | HK97 gp10 family phage protein | NA |
| UHGV-1954134_37 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-1954134_37 | NCBIFam | TIGR01725.1 | HK97-gp10 family putative phage morphogenesis protein | NA |
| UHGV-1954134_37 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-1954134_38 | PHROG | phrog_25 | head closure Hc1 | connector |
| UHGV-1954134_38 | Pfam | PF05521 | Phage head-tail joining protein | Phage_H_T_join |
| UHGV-1954134_38 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-1954134_38 | COG | COG5614 | Phage head-tail adaptor | NA |
| UHGV-1954134_38 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-1954134_39 | eggNOG-mapper | 447909.A6M953_9VIRU | Phage gp6-like head-tail connector protein | NA |
| UHGV-1954134_39 | Pfam | PF05135 | Phage gp6-like head-tail connector protein | Phage_connect_1 |
| UHGV-1954134_39 | NCBIFam | TIGR01560.2 | head-tail connector protein | NA |
| UHGV-1954134_41 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-1954134_41 | UniRef90 | UniRef90_A0A1C6F7A6 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-1954134_41 | eggNOG-mapper | 936154.STP_0852 | phage major capsid protein, HK97 | NA |
| UHGV-1954134_41 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-1954134_41 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-1954134_41 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-1954134_41 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1954134_42 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-1954134_42 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-1954134_42 | UniRef90 | UniRef90_A0A6H3BC34 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-1954134_42 | eggNOG-mapper | 1286171.EAL2_c11050 | Belongs to the peptidase S14 family | NA |
| UHGV-1954134_42 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-1954134_42 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-1954134_42 | Structural annotation | PF00574, MF_00444, NF011090, COG0740 | NA | NA |
| UHGV-1954134_43 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-1954134_43 | UniRef90 | UniRef90_A0A1C6E8K9 | Phage portal protein, HK97 family | NA |
| UHGV-1954134_43 | eggNOG-mapper | 536232.CLM_2933 | Phage portal protein, HK97 family | NA |
| UHGV-1954134_43 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-1954134_43 | NCBIFam | TIGR01537.1 | phage portal protein | NA |
| UHGV-1954134_43 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-1954134_43 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-1954134_45 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-1954134_45 | UniRef90 | UniRef90_A0A150FQX1 | Terminase | NA |
| UHGV-1954134_45 | eggNOG-mapper | 1567010.A0A0A7RU73_9VIRU | Phage Terminase | NA |
| UHGV-1954134_45 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-1954134_45 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-1954134_45 | Structural annotation | PF20441, PF03354, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-1954134_46 | PHROG | phrog_83 | terminase small subunit | head and packaging |
| UHGV-1954134_46 | UniRef90 | UniRef90_UPI0018AA8382 | phage terminase small subunit P27 family | NA |
| UHGV-1954134_46 | eggNOG-mapper | 1291050.JAGE01000001_gene2918 | phage terminase small subunit | NA |
| UHGV-1954134_46 | Pfam | PF05119 | Phage terminase, small subunit | Terminase_4 |
| UHGV-1954134_46 | NCBIFam | TIGR01558.1 | phage terminase small subunit P27 family | NA |
| UHGV-1954134_46 | COG | COG3747 | Phage terminase, small subunit | NA |
| UHGV-1954134_46 | Structural annotation | PF05119, TIGR01558, COG3747 | NA | NA |
| UHGV-1954134_47 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1954134_47 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1954134_47 | UniRef90 | UniRef90_UPI0009DB9931 | DNA cytosine methyltransferase | NA |
| UHGV-1954134_47 | eggNOG-mapper | 1121871.AUAT01000002_gene1371 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1954134_47 | PADLOC | MTase_II_00174 | Type II methyltransferase | RM |
| UHGV-1954134_47 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1954134_47 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1954134_47 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1954134_47 | Structural annotation | PF00145, MF_00786, TIGR00675, COG0270 | NA | NA |