| UHGV-1374526_5 | PHROG | phrog_1313 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1374526_5 | eggNOG-mapper | 536227.CcarbDRAFT_2679 | virulence-associated E family protein | NA |
| UHGV-1374526_5 | Pfam | PF05272 | Virulence-associated protein E-like domain | VapE-like_dom |
| UHGV-1374526_5 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-1374526_5 | Structural annotation | PF05272, PF08800, MF_00175, NF011296, NF040562, COG5545 | NA | NA |
| UHGV-1374526_10 | KOfam | K02334 | dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7] | NA |
| UHGV-1374526_10 | PHROG | phrog_17 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1374526_10 | UniRef90 | UniRef90_A0A7X7HVJ8 | POLAc domain-containing protein | NA |
| UHGV-1374526_10 | eggNOG-mapper | 240302.BN982_00207 | DNA polymerase | NA |
| UHGV-1374526_10 | Pfam | PF01612 | 3'-5' exonuclease | DNA_pol_A_exo1 |
| UHGV-1374526_10 | Pfam | PF00476 | DNA polymerase family A | DNA_pol_A |
| UHGV-1374526_10 | COG | COG0749 | DNA polymerase I, 3'-5' exonuclease and polymerase domains | NA |
| UHGV-1374526_10 | Structural annotation | PF00476, PF01612, MF_04101, NF011541, COG0749 | NA | NA |
| UHGV-1374526_11 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-1374526_11 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1374526_11 | UniRef90 | UniRef90_A0A2E4N2U6 | Helicase C-terminal domain-containing protein | NA |
| UHGV-1374526_11 | eggNOG-mapper | 1203568.HMPREF1484_00226 | SNF2 family N-terminal domain | NA |
| UHGV-1374526_11 | PADLOC | DpdE_00006 | DpdE | DPD |
| UHGV-1374526_11 | Pfam | PF04851 | Type III restriction enzyme, res subunit | ResIII |
| UHGV-1374526_11 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-1374526_11 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-1374526_11 | Structural annotation | PF02399, MF_01821, NF038318, COG0553 | NA | NA |
| UHGV-1374526_12 | PHROG | phrog_69 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1374526_12 | UniRef90 | UniRef90_A0A849UMU7 | NA | NA |
| UHGV-1374526_12 | Pfam | PF10926 | NA | DUF2800 |
| UHGV-1374526_12 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-1374526_12 | Structural annotation | PF10926, MF_03030, TIGR00372, COG2887 | NA | NA |
| UHGV-1374526_13 | Structural annotation | PF18897 | NA | NA |
| UHGV-1374526_14 | PHROG | phrog_1770 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1374526_14 | eggNOG-mapper | 1236504.HMPREF2132_11115 | NA | NA |
| UHGV-1374526_14 | Structural annotation | PF07066, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-1374526_15 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-1374526_15 | UniRef90 | UniRef90_A0A432UK38 | Terminase | NA |
| UHGV-1374526_15 | eggNOG-mapper | 67267.JNXT01000054_gene2976 | A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD | NA |
| UHGV-1374526_15 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-1374526_25 | Structural annotation | PF02408 | NA | NA |
| UHGV-1374526_26 | Structural annotation | PF00139, NF041263, COG3506 | NA | NA |
| UHGV-1374526_29 | Structural annotation | MF_01326_A, NF007260, NF005100 | NA | NA |
| UHGV-1374526_31 | Structural annotation | PF15057, MF_00613, NF002745, TIGR00405, COG5475 | NA | NA |
| UHGV-1374526_36 | Pfam | PF13463 | Winged helix DNA-binding domain | HTH_27 |
| UHGV-1374526_36 | Structural annotation | PF13463, MF_01911, TIGR02337, COG1846 | NA | NA |
| UHGV-1374526_40 | Structural annotation | PF02348, MF_00316, TIGR00466, COG0746 | NA | NA |
| UHGV-1374526_41 | Structural annotation | PF00927, NF033814 | NA | NA |
| UHGV-1374526_42 | Structural annotation | PF03713, MF_01441, NF006975, COG2406 | NA | NA |
| UHGV-1374526_50 | Structural annotation | PF20111, MF_01354 | NA | NA |
| UHGV-1374526_52 | PHROG | phrog_315 | endolysin | lysis |
| UHGV-1374526_52 | UniRef90 | UniRef90_R7DUJ1 | PG_binding_3 domain-containing protein | NA |
| UHGV-1374526_52 | eggNOG-mapper | 349741.Amuc_0129 | Glycosyl hydrolase 108 | NA |
| UHGV-1374526_52 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-1374526_52 | Pfam | PF09374 | Predicted Peptidoglycan domain | PG_binding_3 |
| UHGV-1374526_52 | COG | COG3926 | Lysozyme family protein | NA |
| UHGV-1374526_52 | Structural annotation | NF040573, COG3926 | NA | NA |
| UHGV-1374526_54 | Structural annotation | PF21621, MF_01255, NF007408, COG0662 | NA | NA |
| UHGV-1374526_61 | PHROG | phrog_11324 | nucleotide kinase | other |
| UHGV-1374526_61 | UniRef90 | UniRef90_UPI0009E3027F | NA | NA |
| UHGV-1374526_61 | eggNOG-mapper | 1287276.X752_25920 | NA | NA |
| UHGV-1374526_61 | Pfam | PF11753 | NA | DUF3310 |
| UHGV-1374526_63 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-1374526_63 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-1374526_63 | UniRef90 | UniRef90_A0A2V2F6Y3 | FAD-dependent thymidylate synthase | NA |
| UHGV-1374526_63 | eggNOG-mapper | 509191.AEDB02000067_gene837 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant | NA |
| UHGV-1374526_63 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-1374526_63 | NCBIFam | TIGR02170.1 | FAD-dependent thymidylate synthase | NA |
| UHGV-1374526_63 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-1374526_65 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-1374526_65 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1374526_65 | UniRef90 | UniRef90_A0A0W8E1S8 | DNA ligase (NAD(+)) | NA |
| UHGV-1374526_65 | eggNOG-mapper | 1230457.C476_11811 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-1374526_65 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-1374526_65 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-1374526_65 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-1374526_65 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1374526_65 | Structural annotation | PF01653, PF03120, PF00533, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-1374526_68 | Structural annotation | PF15057, MF_00369, TIGR00739, COG5475, COG1862 | NA | NA |
| UHGV-1374526_80 | Structural annotation | TIGR04203 | NA | NA |
| UHGV-1374526_82 | Structural annotation | MF_02210, NF007025, COG1246 | NA | NA |