| UHGV-0025486_1 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-0025486_1 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-0025486_1 | UniRef90 | UniRef90_UPI001C38B218 | site-specific DNA-methyltransferase | NA |
| UHGV-0025486_1 | eggNOG-mapper | 1196028.ALEF01000043_gene479 | DNA methylase | NA |
| UHGV-0025486_1 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-0025486_1 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-0025486_1 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-0025486_1 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-0025486_2 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-0025486_2 | UniRef90 | UniRef90_A0A096B9T1 | Conjugal transfer protein | NA |
| UHGV-0025486_2 | eggNOG-mapper | 1236504.HMPREF2132_01885 | DNA restriction-modification system | NA |
| UHGV-0025486_2 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-0025486_2 | Structural annotation | PF06325, MF_01947, NF000058, COG2263 | NA | NA |
| UHGV-0025486_3 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-0025486_3 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0025486_3 | UniRef90 | UniRef90_A0A2L2WN54 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-0025486_3 | eggNOG-mapper | 762982.HMPREF9442_01221 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-0025486_3 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-0025486_3 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0025486_3 | Structural annotation | PF01507, MF_00064, NF010367, COG0175 | NA | NA |
| UHGV-0025486_5 | UniRef90 | UniRef90_UPI000237C62E | phage holin family protein | NA |
| UHGV-0025486_5 | eggNOG-mapper | 886379.AEWI01000001_gene1725 | NA | NA |
| UHGV-0025486_5 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0025486_5 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-0025486_6 | Structural annotation | PF20765 | NA | NA |
| UHGV-0025486_8 | KOfam | K20478 | GOLGB1; golgin subfamily B member 1 | NA |
| UHGV-0025486_8 | PHROG | phrog_25337 | tail length tape measure protein | tail |
| UHGV-0025486_8 | UniRef90 | UniRef90_A0A2L2WS53 | PhageMin_Tail domain-containing protein | NA |
| UHGV-0025486_8 | eggNOG-mapper | 1236504.HMPREF2132_01670 | tail tape measure protein, TP901 family | NA |
| UHGV-0025486_8 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0025486_8 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-0025486_8 | Structural annotation | PF10145, TIGR01760 | NA | NA |
| UHGV-0025486_9 | KOfam | K09681 | gltC; LysR family transcriptional regulator, transcription activator of glutamate synthase operon | NA |
| UHGV-0025486_9 | PHROG | phrog_3736 | NA | unknown function |
| UHGV-0025486_9 | UniRef90 | UniRef90_A0A353E8E6 | HTH lysR-type domain-containing protein | NA |
| UHGV-0025486_9 | eggNOG-mapper | 762982.HMPREF9442_01735 | LysR substrate binding domain | NA |
| UHGV-0025486_9 | Pfam | PF00126 | Bacterial regulatory helix-turn-helix protein, lysR family | HTH_1 |
| UHGV-0025486_9 | Pfam | PF03466 | LysR substrate binding domain | LysR_substrate |
| UHGV-0025486_9 | COG | COG0583 | DNA-binding transcriptional regulator, LysR family | NA |
| UHGV-0025486_9 | Structural annotation | PF03466, PF00126, MF_01233, NF040786, COG0583 | NA | NA |
| UHGV-0025486_12 | Structural annotation | PF10628 | NA | NA |
| UHGV-0025486_15 | UniRef90 | UniRef90_A0A2L2WND9 | Primase C terminal 2 | NA |
| UHGV-0025486_15 | eggNOG-mapper | 1236504.HMPREF2132_01765 | Primase C terminal 2 (PriCT-2) | NA |
| UHGV-0025486_15 | PADLOC | drt-cluster64 | DRT | DRT |
| UHGV-0025486_15 | Pfam | PF08800 | BT4734-like, N-terminal domain | BT4734-like_N |
| UHGV-0025486_15 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-0025486_15 | Structural annotation | PF08800, NF040562 | NA | NA |
| UHGV-0025486_16 | eggNOG-mapper | 483215.BACFIN_04730 | NA | NA |
| UHGV-0025486_17 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-0025486_17 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-0025486_17 | UniRef90 | UniRef90_A0A354WXC5 | Guanylate kinase | NA |
| UHGV-0025486_17 | eggNOG-mapper | 1433126.BN938_1741 | Guanylate kinase | NA |
| UHGV-0025486_17 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-0025486_17 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-0025486_17 | Structural annotation | PF00625, MF_00328, TIGR03263, COG0194 | NA | NA |
| UHGV-0025486_18 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0025486_18 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0025486_18 | UniRef90 | UniRef90_A0A8F0WBE8 | Flavin-dependent thymidylate synthase | NA |
| UHGV-0025486_18 | eggNOG-mapper | 1236504.HMPREF2132_01775 | thymidylate synthase (FAD) activity | NA |
| UHGV-0025486_18 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0025486_18 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0025486_18 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0025486_19 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-0025486_19 | UniRef90 | UniRef90_A0A353E7W6 | MazG domain-containing protein | NA |
| UHGV-0025486_19 | eggNOG-mapper | 1236504.HMPREF2132_01780 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-0025486_19 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-0025486_19 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-0025486_19 | Structural annotation | TIGR03188, COG1694 | NA | NA |
| UHGV-0025486_22 | Structural annotation | PF11550, COG5437 | NA | NA |
| UHGV-0025486_23 | KOfam | K21511 | GPC; capsid assembly protease [EC:3.4.21.-] | NA |
| UHGV-0025486_23 | PHROG | phrog_53 | head maturation protease | head and packaging |
| UHGV-0025486_23 | UniRef90 | UniRef90_A0A2L2WN07 | Signal peptide peptidase SppA, 36K type | NA |
| UHGV-0025486_23 | eggNOG-mapper | 1236504.HMPREF2132_01855 | serine-type peptidase activity | NA |
| UHGV-0025486_23 | COG | COG0616 | Periplasmic serine protease, ClpP class | NA |
| UHGV-0025486_23 | Structural annotation | PF01343, MF_00444, TIGR00706, COG0616 | NA | NA |
| UHGV-0025486_24 | Structural annotation | PF05065, PF18998, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0025486_25 | Structural annotation | TIGR01603, COG5437 | NA | NA |
| UHGV-0025486_26 | KOfam | K22918 | ttsA; typhoid toxin secretion A | NA |
| UHGV-0025486_26 | PHROG | phrog_315 | endolysin | lysis |
| UHGV-0025486_26 | UniRef90 | UniRef90_A0A353E8E0 | Peptidoglycan domain protein | NA |
| UHGV-0025486_26 | eggNOG-mapper | 357276.EL88_12865 | Predicted Peptidoglycan domain | NA |
| UHGV-0025486_26 | Pfam | PF05838 | Glycosyl hydrolase 108 | Glyco_hydro_108 |
| UHGV-0025486_26 | Pfam | PF09374 | Predicted Peptidoglycan domain | PG_binding_3 |
| UHGV-0025486_26 | COG | COG3926 | Lysozyme family protein | NA |
| UHGV-0025486_26 | Structural annotation | PF05838, PF09374, NF040573, COG3926 | NA | NA |
| UHGV-0025486_30 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0025486_36 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0025486_36 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0025486_36 | UniRef90 | UniRef90_A0A353E5E4 | Cytosine-specific methyltransferase | NA |
| UHGV-0025486_36 | eggNOG-mapper | 1033733.CAEK01000007_gene1648 | Cytosine-specific methyltransferase | NA |
| UHGV-0025486_36 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-0025486_36 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0025486_36 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0025486_36 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0025486_36 | Structural annotation | PF00145, MF_02237, TIGR00675, COG0270 | NA | NA |
| UHGV-0025486_46 | KOfam | K14415 | RTCB, rtcB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] | NA |
| UHGV-0025486_46 | PHROG | phrog_1075 | tRNA splicing ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0025486_46 | UniRef90 | UniRef90_A0A413CCX6 | RNA-splicing ligase RtcB | NA |
| UHGV-0025486_46 | eggNOG-mapper | 1089548.KI783301_gene2001 | tRNA-splicing ligase RtcB | NA |
| UHGV-0025486_46 | Pfam | PF01139 | tRNA-splicing ligase RtcB | RtcB |
| UHGV-0025486_46 | COG | COG1690 | RNA-splicing ligase RtcB, repairs tRNA damage | NA |
| UHGV-0025486_46 | Structural annotation | PF01139, MF_03144, NF007153, COG1690 | NA | NA |
| UHGV-0025486_48 | Structural annotation | PF13619 | NA | NA |
| UHGV-0025486_49 | eggNOG-mapper | 1235803.C825_03414 | NA | NA |
| UHGV-0025486_49 | Structural annotation | PF05136, MF_04135, TIGR01540, COG5518 | NA | NA |
| UHGV-0025486_50 | Pfam | PF20459 | NA | DUF6712 |
| UHGV-0025486_50 | Structural annotation | PF20459 | NA | NA |
| UHGV-0025486_55 | PHROG | phrog_38044 | NA | unknown function |
| UHGV-0025486_55 | UniRef90 | UniRef90_A0A1H5RXL6 | Peptidase S74 domain-containing protein | NA |
| UHGV-0025486_55 | eggNOG-mapper | 762982.HMPREF9442_01191 | cellulase activity | NA |
| UHGV-0025486_55 | COG | COG4733 | Phage-related protein, tail protein J | NA |
| UHGV-0025486_59 | Structural annotation | PF10043 | NA | NA |
| UHGV-0025486_61 | UniRef90 | UniRef90_R6YPV7 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0025486_61 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0025486_62 | KOfam | K07339 | hicA; mRNA interferase HicA [EC:3.1.-.-] | NA |
| UHGV-0025486_62 | UniRef90 | UniRef90_A0A413UUX1 | Type II toxin-antitoxin system HicA family toxin | NA |
| UHGV-0025486_62 | eggNOG-mapper | 517433.PanABDRAFT_4268 | HicA toxin of bacterial toxin-antitoxin, | NA |
| UHGV-0025486_62 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-0025486_62 | COG | COG1724 | Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family | NA |
| UHGV-0025486_63 | UniRef90 | UniRef90_A0A7Y5JE15 | Helix-turn-helix transcriptional regulator | NA |
| UHGV-0025486_63 | eggNOG-mapper | 929556.Solca_2323 | NA | NA |
| UHGV-0025486_63 | COG | COG1598 | Antitoxin component HicB of the HicAB toxin-antitoxin system | NA |
| UHGV-0025486_63 | Structural annotation | PF21748, NF041951, COG1598 | NA | NA |
| UHGV-0025486_64 | PHROG | phrog_1373 | transcriptional regulator | transcription regulation |
| UHGV-0025486_64 | UniRef90 | UniRef90_A0A449I4P1 | Regulatory protein | NA |
| UHGV-0025486_64 | eggNOG-mapper | 1268240.ATFI01000020_gene152 | NA | NA |
| UHGV-0025486_64 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0025486_64 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0025486_64 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0025486_67 | KOfam | K07729 | K07729; putative transcriptional regulator | NA |
| UHGV-0025486_67 | PHROG | phrog_3 | transcriptional repressor | transcription regulation |
| UHGV-0025486_67 | UniRef90 | UniRef90_A0A415NVE9 | XRE family transcriptional regulator | NA |
| UHGV-0025486_67 | eggNOG-mapper | 449673.BACSTE_00558 | NA | NA |
| UHGV-0025486_67 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0025486_67 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0025486_67 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-0025486_70 | UniRef90 | UniRef90_A0A1Q6HQB5 | Transcriptional regulator | NA |
| UHGV-0025486_70 | eggNOG-mapper | 1268240.ATFI01000020_gene152 | NA | NA |
| UHGV-0025486_70 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0025486_70 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0025486_70 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-0025486_71 | PHROG | phrog_15863 | NA | unknown function |
| UHGV-0025486_71 | Structural annotation | PF18847 | NA | NA |
| UHGV-0025486_72 | UniRef90 | UniRef90_A0A849X300 | NA | NA |
| UHGV-0025486_72 | eggNOG-mapper | 1121098.HMPREF1534_01670 | NA | NA |
| UHGV-0025486_72 | Structural annotation | PF11171 | NA | NA |
| UHGV-0025486_74 | UniRef90 | UniRef90_UPI001EFF9E51 | phage antirepressor KilAC domain-containing protein | NA |
| UHGV-0025486_74 | eggNOG-mapper | 411901.BACCAC_01209 | BRO family, N-terminal domain | NA |
| UHGV-0025486_74 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-0025486_74 | Structural annotation | COG3561 | NA | NA |
| UHGV-0025486_82 | Structural annotation | PF06289, COG1582 | NA | NA |
| UHGV-0025486_84 | Structural annotation | PF11797, MF_00791, NF003967, COG2967 | NA | NA |
| UHGV-0025486_85 | Structural annotation | PF20200, NF038041, COG4704 | NA | NA |
| UHGV-0025486_86 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-0025486_86 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-0025486_86 | UniRef90 | UniRef90_A0A095Z6L5 | AAA_31 domain-containing protein | NA |
| UHGV-0025486_86 | eggNOG-mapper | 1236504.HMPREF2132_02105 | CobQ CobB MinD ParA nucleotide binding domain | NA |
| UHGV-0025486_86 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-0025486_86 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-0025486_86 | Structural annotation | PF13614, MF_00533, NF041283, COG1192 | NA | NA |
| UHGV-0025486_87 | Structural annotation | PF03869, NF010302, COG3905 | NA | NA |
| UHGV-0025486_88 | UniRef90 | UniRef90_R5TW50 | Initiator RepB protein | NA |
| UHGV-0025486_88 | eggNOG-mapper | 1095752.HMPREF9969_0713 | Initiator RepB protein | NA |
| UHGV-0025486_88 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-0025486_88 | Structural annotation | PF20964, PF01051, NF038290, COG5527 | NA | NA |
| UHGV-0025486_91 | Structural annotation | PF17457 | NA | NA |
| UHGV-0025486_92 | Structural annotation | COG3655 | NA | NA |
| UHGV-0025486_94 | PHROG | phrog_255 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0025486_94 | UniRef90 | UniRef90_A0A355U3Z6 | NA | NA |
| UHGV-0025486_94 | eggNOG-mapper | 1236504.HMPREF2132_01690 | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease | NA |
| UHGV-0025486_94 | Pfam | PF16473 | 3'-5' exoribonuclease Rv2179c-like domain | Rv2179c-like |
| UHGV-0025486_94 | COG | COG0847 | DNA polymerase III, epsilon subunit or related 3'-5' exonuclease | NA |
| UHGV-0025486_94 | Structural annotation | PF16473, MF_00157, TIGR01298, COG5018 | NA | NA |
| UHGV-0025486_96 | UniRef90 | UniRef90_A0A096AGU9 | FHA domain-containing protein | NA |
| UHGV-0025486_96 | eggNOG-mapper | 1236504.HMPREF2132_01700 | DNA primase activity | NA |
| UHGV-0025486_96 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0025486_96 | Structural annotation | PF05272, PF01807, MF_00974, MF_00016, NF005477, COG3378, COG0358 | NA | NA |
| UHGV-0025486_100 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-0025486_100 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-0025486_100 | UniRef90 | UniRef90_A0A7X8F565 | Beta sliding clamp | NA |
| UHGV-0025486_100 | eggNOG-mapper | 411477.PARMER_01865 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-0025486_100 | Pfam | PF00712 | DNA polymerase III beta subunit, N-terminal domain | DNA_pol3_beta |
| UHGV-0025486_100 | Pfam | PF02768 | DNA polymerase III beta subunit, C-terminal domain | DNA_pol3_beta_3 |
| UHGV-0025486_100 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-0025486_100 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-0025486_102 | Structural annotation | PF08863 | NA | NA |
| UHGV-0025486_107 | PHROG | phrog_4433 | NA | unknown function |
| UHGV-0025486_107 | eggNOG-mapper | 767434.Fraau_1460 | regulation of DNA-templated transcription, elongation | NA |
| UHGV-0025486_107 | COG | COG5164 | Transcription elongation factor SPT5 | NA |
| UHGV-0025486_107 | Structural annotation | NF007410 | NA | NA |
| UHGV-0025486_108 | PHROG | phrog_4433 | NA | unknown function |
| UHGV-0025486_108 | eggNOG-mapper | 619693.HMPREF6745_2502 | DNA-templated transcription, initiation | NA |
| UHGV-0025486_108 | COG | COG5164 | Transcription elongation factor SPT5 | NA |
| UHGV-0025486_108 | Structural annotation | NF007410 | NA | NA |
| UHGV-0025486_110 | eggNOG-mapper | 1002367.HMPREF0673_02207 | NA | NA |
| UHGV-0025486_110 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |