| UHGV-0033558_2 | PHROG | phrog_236 | nucleotide kinase | other |
| UHGV-0033558_2 | UniRef90 | UniRef90_A0A4Q2K614 | NA | NA |
| UHGV-0033558_2 | eggNOG-mapper | 445975.COLSTE_02179 | NA | NA |
| UHGV-0033558_2 | Pfam | PF11753 | NA | DUF3310 |
| UHGV-0033558_2 | Structural annotation | PF11753 | NA | NA |
| UHGV-0033558_3 | eggNOG-mapper | 97139.C824_00133 | NA | NA |
| UHGV-0033558_7 | KOfam | K14059 | int; integrase | NA |
| UHGV-0033558_7 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0033558_7 | UniRef90 | UniRef90_A0A4Q2K1M9 | Site-specific integrase | NA |
| UHGV-0033558_7 | eggNOG-mapper | 445975.COLSTE_02176 | Belongs to the 'phage' integrase family | NA |
| UHGV-0033558_7 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0033558_7 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0033558_7 | Structural annotation | PF00589, PF13102, MF_01808, TIGR02224, COG4974 | NA | NA |
| UHGV-0033558_8 | PHROG | phrog_21723 | NA | unknown function |
| UHGV-0033558_8 | UniRef90 | UniRef90_A0A414EU10 | Integration host factor | NA |
| UHGV-0033558_8 | eggNOG-mapper | 479437.Elen_1661 | integration host factor | NA |
| UHGV-0033558_8 | NCBIFam | NF041260.1 | integration host factor, actinobacterial type | NA |
| UHGV-0033558_8 | COG | COG0099 | Ribosomal protein S13 | NA |
| UHGV-0033558_8 | Structural annotation | PF00416, MF_01315, NF041260, COG0099 | NA | NA |
| UHGV-0033558_10 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0033558_10 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0033558_10 | UniRef90 | UniRef90_A0A374TTE0 | Single-stranded DNA-binding protein | NA |
| UHGV-0033558_10 | eggNOG-mapper | 1111135.HMPREF1248_1228 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-0033558_10 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0033558_10 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0033558_10 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0033558_10 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0033558_10 | Structural annotation | PF00436, MF_00984, NF005406, COG0629 | NA | NA |
| UHGV-0033558_11 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-0033558_11 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-0033558_11 | UniRef90 | UniRef90_A0A374TU31 | dUTP diphosphatase | NA |
| UHGV-0033558_11 | eggNOG-mapper | 445975.COLSTE_02170 | This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | NA |
| UHGV-0033558_11 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-0033558_11 | NCBIFam | NF001862.0 | dUTP diphosphatase | NA |
| UHGV-0033558_11 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-0033558_11 | Structural annotation | PF00692, MF_00116, NF001862, COG0756 | NA | NA |
| UHGV-0033558_12 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0033558_12 | eggNOG-mapper | 445975.COLSTE_02169 | NA | NA |
| UHGV-0033558_12 | Structural annotation | PF04545, MF_00674, TIGR03879 | NA | NA |
| UHGV-0033558_13 | KOfam | K07451 | mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] | NA |
| UHGV-0033558_13 | PHROG | phrog_119 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0033558_13 | UniRef90 | UniRef90_A0A4Q2K147 | HNH endonuclease | NA |
| UHGV-0033558_13 | eggNOG-mapper | 445975.COLSTE_02167 | endonuclease activity | NA |
| UHGV-0033558_13 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0033558_13 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0033558_14 | PHROG | phrog_1066 | NA | unknown function |
| UHGV-0033558_14 | eggNOG-mapper | 445975.COLSTE_02166 | NA | NA |
| UHGV-0033558_14 | Structural annotation | TIGR01558 | NA | NA |
| UHGV-0033558_15 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-0033558_15 | UniRef90 | UniRef90_A0A374TTV6 | Terminase large subunit | NA |
| UHGV-0033558_15 | eggNOG-mapper | 445975.COLSTE_02165 | Phage Terminase | NA |
| UHGV-0033558_15 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-0033558_15 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-0033558_15 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-0033558_15 | Structural annotation | PF20441, PF03354, MF_04145, TIGR01547, COG4626 | NA | NA |
| UHGV-0033558_16 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-0033558_16 | UniRef90 | UniRef90_A0A4Q2K609 | Phage portal protein | NA |
| UHGV-0033558_16 | eggNOG-mapper | 445975.COLSTE_02164 | Phage portal protein | NA |
| UHGV-0033558_16 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-0033558_16 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-0033558_16 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0033558_17 | KOfam | K06904 | NA | NA |
| UHGV-0033558_17 | PHROG | phrog_80 | head maturation protease | head and packaging |
| UHGV-0033558_17 | UniRef90 | UniRef90_A0A414ETZ5 | HK97 family phage prohead protease | NA |
| UHGV-0033558_17 | eggNOG-mapper | 445975.COLSTE_02163 | Caudovirus prohead serine protease | NA |
| UHGV-0033558_17 | Pfam | PF04586 | Caudovirus prohead serine protease | Peptidase_S78 |
| UHGV-0033558_17 | NCBIFam | TIGR01543.1 | HK97 family phage prohead protease | NA |
| UHGV-0033558_17 | COG | COG3740 | Phage head maturation protease | NA |
| UHGV-0033558_17 | Structural annotation | PF04586, TIGR01543, COG3740 | NA | NA |
| UHGV-0033558_18 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0033558_18 | UniRef90 | UniRef90_A0A4Q2K3E6 | Phage major capsid protein | NA |
| UHGV-0033558_18 | eggNOG-mapper | 445975.COLSTE_02162 | Phage capsid family | NA |
| UHGV-0033558_18 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0033558_18 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0033558_18 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0033558_18 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0033558_19 | PHROG | phrog_5223 | neck protein | connector |
| UHGV-0033558_19 | UniRef90 | UniRef90_A0A4Q2K0G6 | DNA-packaging protein | NA |
| UHGV-0033558_19 | eggNOG-mapper | 1444310.JANV01000004_gene2679 | NA | NA |
| UHGV-0033558_19 | Structural annotation | TIGR01560 | NA | NA |
| UHGV-0033558_20 | PHROG | phrog_1951 | head-tail adaptor | connector |
| UHGV-0033558_20 | UniRef90 | UniRef90_A0A6N7RLQ4 | Phage head-tail adapter protein | NA |
| UHGV-0033558_20 | eggNOG-mapper | 491915.Aflv_0668 | head-tail adaptor | NA |
| UHGV-0033558_20 | COG | COG5614 | Phage head-tail adaptor | NA |
| UHGV-0033558_20 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-0033558_21 | UniRef90 | UniRef90_A0A1H3XBH5 | Bacteriophage HK97-gp10, putative tail-component | NA |
| UHGV-0033558_21 | eggNOG-mapper | 1220589.CD32_00820 | NA | NA |
| UHGV-0033558_21 | Structural annotation | PF20039, TIGR01725, COG5005 | NA | NA |
| UHGV-0033558_22 | eggNOG-mapper | 411473.RUMCAL_01153 | NA | NA |
| UHGV-0033558_22 | Structural annotation | PF05657 | NA | NA |
| UHGV-0033558_23 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-0033558_23 | UniRef90 | UniRef90_B6GDH7 | Phage major tail protein, phi13 family | NA |
| UHGV-0033558_23 | eggNOG-mapper | 445975.COLSTE_02157 | phage major tail protein, phi13 family | NA |
| UHGV-0033558_23 | NCBIFam | TIGR01603.1 | major tail protein | NA |
| UHGV-0033558_23 | Structural annotation | PF06488, TIGR01603, COG3498 | NA | NA |
| UHGV-0033558_24 | Structural annotation | PF12363 | NA | NA |
| UHGV-0033558_26 | PHROG | phrog_23464 | NA | unknown function |
| UHGV-0033558_26 | UniRef90 | UniRef90_B6GDH5 | TMP repeat protein | NA |
| UHGV-0033558_26 | eggNOG-mapper | 445975.COLSTE_02155 | Phage tail tape measure protein TP901 | NA |
| UHGV-0033558_26 | COG | COG5280 | Phage-related minor tail protein | NA |
| UHGV-0033558_26 | Structural annotation | COG5280 | NA | NA |
| UHGV-0033558_27 | PHROG | phrog_202 | distal tail protein Dit | tail |
| UHGV-0033558_27 | UniRef90 | UniRef90_B6GDH4 | Putative phage tail component domain protein | NA |
| UHGV-0033558_27 | eggNOG-mapper | 445975.COLSTE_02154 | phage tail | NA |
| UHGV-0033558_27 | Pfam | PF05709 | Phage tail protein RIFT-related domain | Sipho_tail |
| UHGV-0033558_27 | NCBIFam | TIGR01633.1 | distal tail protein Dit | NA |
| UHGV-0033558_27 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0033558_27 | Structural annotation | PF05709, PF20753, TIGR01633, COG4722 | NA | NA |
| UHGV-0033558_28 | PHROG | phrog_12312 | virion structural protein | head and packaging |
| UHGV-0033558_28 | UniRef90 | UniRef90_A0A4Q2K438 | Prophage_tail domain-containing protein | NA |
| UHGV-0033558_28 | eggNOG-mapper | 445975.COLSTE_02153 | Prophage endopeptidase tail | NA |
| UHGV-0033558_28 | Pfam | PF06605 | Prophage endopeptidase tail | Prophage_tail |
| UHGV-0033558_28 | NCBIFam | TIGR01665.1 | phage tail spike protein | NA |
| UHGV-0033558_28 | COG | COG4926 | Phage-related protein | NA |
| UHGV-0033558_28 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-0033558_31 | PHROG | phrog_19280 | NA | unknown function |
| UHGV-0033558_31 | UniRef90 | UniRef90_A0A4Q2K310 | NA | NA |
| UHGV-0033558_31 | eggNOG-mapper | 445975.COLSTE_02151 | NA | NA |
| UHGV-0033558_31 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-0033558_31 | Structural annotation | PF10651 | NA | NA |
| UHGV-0033558_32 | PHROG | phrog_17147 | NA | unknown function |
| UHGV-0033558_32 | UniRef90 | UniRef90_A0A1M6MWL0 | N-terminal domain of peptidoglycan hydrolase CwlO-containing protein | NA |
| UHGV-0033558_32 | eggNOG-mapper | 1680.BADO_1222 | NA | NA |
| UHGV-0033558_32 | Structural annotation | PF21430 | NA | NA |
| UHGV-0033558_33 | KOfam | K00986 | ltrA; RNA-directed DNA polymerase [EC:2.7.7.49] | NA |
| UHGV-0033558_33 | PHROG | phrog_1423 | Reverse transcriptase | DNA, RNA and nucleotide metabolism |
| UHGV-0033558_33 | UniRef90 | UniRef90_A0A4Q2K0U8 | Reverse transcriptase domain-containing protein | NA |
| UHGV-0033558_33 | eggNOG-mapper | 33035.JPJF01000043_gene1000 | Reverse transcriptase (RNA-dependent DNA polymerase) | NA |
| UHGV-0033558_33 | PADLOC | icity0040 | RT (reverse transcriptase) | CRISPR-CAS |
| UHGV-0033558_33 | Pfam | PF00078 | Reverse transcriptase (RNA-dependent DNA polymerase) | RVT_1 |
| UHGV-0033558_33 | COG | COG3344 | Retron-type reverse transcriptase | NA |
| UHGV-0033558_33 | Structural annotation | PF00078, MF_01390, TIGR04416, COG3344 | NA | NA |
| UHGV-0033558_35 | UniRef90 | UniRef90_A0A8A5ZEZ9 | ASCH domain-containing protein | NA |
| UHGV-0033558_35 | NCBIFam | NF040910.1 | CD1375 family protein | NA |
| UHGV-0033558_35 | Structural annotation | NF040910 | NA | NA |
| UHGV-0033558_36 | UniRef90 | UniRef90_UPI0011067090 | phage holin family protein | NA |
| UHGV-0033558_36 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0033558_36 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-0033558_37 | UniRef90 | UniRef90_A0A4Q2K4W9 | Peptidase_C39_2 domain-containing protein | NA |
| UHGV-0033558_37 | Pfam | PF13529 | Peptidase_C39 like family | Peptidase_C39_2 |
| UHGV-0033558_37 | COG | COG0741 | Soluble lytic murein transglycosylase or regulatory protein s ( may contain LysM/invasin domain) | NA |
| UHGV-0033558_37 | Structural annotation | PF03412, NF033920, COG3271 | NA | NA |
| UHGV-0033558_38 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-0033558_38 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-0033558_38 | UniRef90 | UniRef90_B6GDG2 | Glycosyl hydrolase family 25 | NA |
| UHGV-0033558_38 | eggNOG-mapper | 445975.COLSTE_02142 | CW_7 repeat | NA |
| UHGV-0033558_38 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-0033558_38 | Pfam | PF08230 | CW_7 repeat | CW_7 |
| UHGV-0033558_38 | COG | COG1388 | LysM repeat | NA |
| UHGV-0033558_38 | Structural annotation | PF01183, PF01476, TIGR02899, COG3757, COG1388 | NA | NA |
| UHGV-0033558_39 | eggNOG-mapper | 1203602.HMPREF1527_01098 | NA | NA |
| UHGV-0033558_42 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-0033558_42 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-0033558_42 | UniRef90 | UniRef90_UPI001314BC37 | recombinase family protein | NA |
| UHGV-0033558_42 | eggNOG-mapper | 445975.COLSTE_02191 | Recombinase zinc beta ribbon domain | NA |
| UHGV-0033558_42 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-0033558_42 | Pfam | PF07508 | Recombinase | Recombinase |
| UHGV-0033558_42 | Pfam | PF13408 | Recombinase zinc beta ribbon domain | Zn_ribbon_recom |
| UHGV-0033558_42 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-0033558_42 | Structural annotation | PF00239, NF041201, COG2452 | NA | NA |
| UHGV-0033558_43 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-0033558_43 | UniRef90 | UniRef90_A0A4Q2K3G5 | XRE family transcriptional regulator | NA |
| UHGV-0033558_43 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0033558_43 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-0033558_43 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0033558_44 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-0033558_44 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0033558_44 | UniRef90 | UniRef90_A0A4Q2K0I4 | XRE family transcriptional regulator | NA |
| UHGV-0033558_44 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0033558_44 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0033558_44 | Structural annotation | PF13443, NF041951, COG1396 | NA | NA |
| UHGV-0033558_47 | eggNOG-mapper | 445975.COLSTE_02184 | NA | NA |
| UHGV-0033558_49 | PHROG | phrog_24189 | NA | unknown function |
| UHGV-0033558_49 | UniRef90 | UniRef90_A0A4Q2K0F6 | NA | NA |
| UHGV-0033558_49 | eggNOG-mapper | 445975.COLSTE_02182 | NA | NA |
| UHGV-0033558_49 | Pfam | PF14297 | Lin1244/Lin1753-like, N-terminal | Lin1244_N |
| UHGV-0033558_49 | Structural annotation | PF14297, TIGR01714, COG1959 | NA | NA |
| UHGV-0033558_52 | PHROG | phrog_24658 | NA | unknown function |
| UHGV-0033558_52 | UniRef90 | UniRef90_R7D8J1 | Gp50 | NA |
| UHGV-0033558_53 | PHROG | phrog_599 | Lar-like restriction alleviation protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-0033558_53 | UniRef90 | UniRef90_A0A4Q2K4Y8 | Restriction alleviation protein, Lar family | NA |
| UHGV-0033558_53 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-0033558_53 | NCBIFam | TIGR03655.1 | Lar family restriction alleviation protein | NA |
| UHGV-0033558_53 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-0033558_53 | Structural annotation | PF14354, NF007260 | NA | NA |