| UHGV-0024630_3 | KOfam | K03581 | recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] | NA |
| UHGV-0024630_3 | PHROG | phrog_325 | Dda-like helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_3 | UniRef90 | UniRef90_A0A843GQ82 | AAA family ATPase | NA |
| UHGV-0024630_3 | eggNOG-mapper | 1449065.JMLL01000011_gene2471 | COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member | NA |
| UHGV-0024630_3 | PADLOC | cluster10 | RecD_0_IVD | CRISPR-CAS |
| UHGV-0024630_3 | Pfam | PF13604 | AAA domain | AAA_30 |
| UHGV-0024630_3 | Pfam | PF13538 | UvrD-like helicase C-terminal domain | UvrD_C_2 |
| UHGV-0024630_3 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0024630_3 | Structural annotation | PF13604, MF_01488, TIGR01448, COG0507 | NA | NA |
| UHGV-0024630_4 | Structural annotation | COG3189 | NA | NA |
| UHGV-0024630_5 | KOfam | K02337 | dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] | NA |
| UHGV-0024630_5 | PHROG | phrog_405 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_5 | UniRef90 | UniRef90_A0A345BQ00 | DNA-directed DNA polymerase | NA |
| UHGV-0024630_5 | eggNOG-mapper | 224308.BSU20340 | DNA polymerase | NA |
| UHGV-0024630_5 | Pfam | PF02811 | PHP domain | PHP |
| UHGV-0024630_5 | Pfam | PF07733 | Bacterial DNA polymerase III alpha NTPase domain | DNA_pol3_alpha |
| UHGV-0024630_5 | Pfam | PF17657 | Bacterial DNA polymerase III alpha subunit finger domain | DNA_pol3_finger |
| UHGV-0024630_5 | Pfam | PF14579 | Helix-hairpin-helix motif | HHH_6 |
| UHGV-0024630_5 | COG | COG0587 | DNA polymerase III, alpha subunit | NA |
| UHGV-0024630_5 | Structural annotation | PF07733, PF02811, PF17657, PF14579, MF_01902, NF005617, COG0587 | NA | NA |
| UHGV-0024630_6 | PHROG | phrog_236 | nucleotide kinase | other |
| UHGV-0024630_6 | UniRef90 | UniRef90_UPI001D150D86 | NA | NA |
| UHGV-0024630_6 | eggNOG-mapper | 411473.RUMCAL_00920 | NA | NA |
| UHGV-0024630_6 | Pfam | PF11753 | NA | DUF3310 |
| UHGV-0024630_7 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-0024630_7 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-0024630_7 | UniRef90 | UniRef90_R7F5N5 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0024630_7 | eggNOG-mapper | 500635.MITSMUL_03099 | Ribonucleoside-triphosphate reductase | NA |
| UHGV-0024630_7 | Pfam | PF03477 | ATP cone domain | ATP-cone |
| UHGV-0024630_7 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-0024630_7 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0024630_7 | Structural annotation | PF13597, PF03477, MF_00440, MF_02058, NF006732, COG1328 | NA | NA |
| UHGV-0024630_8 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_8 | UniRef90 | UniRef90_A0A317U9F9 | HNHc domain-containing protein | NA |
| UHGV-0024630_8 | eggNOG-mapper | 525257.HMPREF0204_11331 | HNH endonuclease | NA |
| UHGV-0024630_8 | Pfam | PF13392 | HNH endonuclease | HNH_3 |
| UHGV-0024630_8 | Structural annotation | PF20987 | NA | NA |
| UHGV-0024630_9 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-0024630_9 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-0024630_9 | UniRef90 | UniRef90_A0A1L5KUQ7 | Putative transposase DNA-binding domain (Fragment) | NA |
| UHGV-0024630_9 | eggNOG-mapper | 1042156.CXIVA_13410 | Ribonucleoside-triphosphate reductase | NA |
| UHGV-0024630_9 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-0024630_9 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0024630_10 | KOfam | K04068 | nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] | NA |
| UHGV-0024630_10 | PHROG | phrog_626 | anaerobic ribonucleotide reductase small subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_10 | UniRef90 | UniRef90_A0A843FG79 | Anaerobic ribonucleoside-triphosphate reductase activating protein | NA |
| UHGV-0024630_10 | eggNOG-mapper | 1401067.HMPREF0872_03965 | Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine | NA |
| UHGV-0024630_10 | Pfam | PF13353 | 4Fe-4S single cluster domain | Fer4_12 |
| UHGV-0024630_10 | NCBIFam | TIGR02491.1 | anaerobic ribonucleoside-triphosphate reductase activating protein | NA |
| UHGV-0024630_10 | COG | COG0602 | Organic radical activating enzyme NrdG/QueE | NA |
| UHGV-0024630_10 | Structural annotation | PF13353, MF_00917, TIGR02491, COG0602 | NA | NA |
| UHGV-0024630_12 | Structural annotation | PF18844, NF001026, COG4820 | NA | NA |
| UHGV-0024630_13 | PHROG | phrog_4538 | NA | unknown function |
| UHGV-0024630_13 | UniRef90 | UniRef90_UPI001C7D2EEC | zinc-ribbon domain-containing protein | NA |
| UHGV-0024630_13 | eggNOG-mapper | 1236976.JCM16418_1598 | Restriction endonuclease | NA |
| UHGV-0024630_13 | COG | COG3440 | Predicted restriction endonuclease | NA |
| UHGV-0024630_14 | Structural annotation | PF10750, MF_01122, TIGR00285, COG1581 | NA | NA |
| UHGV-0024630_15 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-0024630_15 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_15 | UniRef90 | UniRef90_A0A1T5BGQ6 | dUTP pyrophosphatase | NA |
| UHGV-0024630_15 | eggNOG-mapper | 1280685.AUKC01000002_gene2744 | dUTPase | NA |
| UHGV-0024630_15 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-0024630_15 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-0024630_15 | Structural annotation | PF00692, MF_00116, TIGR00576, COG0756 | NA | NA |
| UHGV-0024630_16 | PHROG | phrog_827 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_16 | UniRef90 | UniRef90_UPI00189AB244 | crossover junction endodeoxyribonuclease RuvC | NA |
| UHGV-0024630_16 | Structural annotation | PF07066, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-0024630_17 | eggNOG-mapper | 658655.HMPREF0988_00914 | NA | NA |
| UHGV-0024630_19 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-0024630_19 | UniRef90 | UniRef90_A0A345BPX4 | Carbohydrate binding domain/collagen triple helix repeat protein | NA |
| UHGV-0024630_19 | eggNOG-mapper | 1226322.HMPREF1545_00077 | NA | NA |
| UHGV-0024630_19 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-0024630_20 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0024630_20 | eggNOG-mapper | 476272.RUMHYD_01770 | NA | NA |
| UHGV-0024630_21 | eggNOG-mapper | 476272.RUMHYD_01953 | NA | NA |
| UHGV-0024630_22 | eggNOG-mapper | 658655.HMPREF0988_00919 | NA | NA |
| UHGV-0024630_22 | Structural annotation | NF033819 | NA | NA |
| UHGV-0024630_23 | Structural annotation | PF21621 | NA | NA |
| UHGV-0024630_25 | UniRef90 | UniRef90_A0A345BQ08 | Carbohydrate binding domain protein | NA |
| UHGV-0024630_25 | Structural annotation | PF16990, NF033675 | NA | NA |
| UHGV-0024630_26 | PHROG | phrog_32343 | NA | unknown function |
| UHGV-0024630_26 | UniRef90 | UniRef90_A0A345BPW9 | Putative flagellin-like protein | NA |
| UHGV-0024630_26 | eggNOG-mapper | 574375.BAGA_05825 | bacterial-type flagellum-dependent cell motility | NA |
| UHGV-0024630_26 | COG | COG1344 | Flagellin and related hook-associated protein FlgL | NA |
| UHGV-0024630_26 | Structural annotation | PF06605, COG4379 | NA | NA |
| UHGV-0024630_27 | PHROG | phrog_30026 | NA | unknown function |
| UHGV-0024630_27 | Structural annotation | PF19266, PF02010, MF_04116, TIGR03503, COG3499, COG2372 | NA | NA |
| UHGV-0024630_28 | KOfam | K01448 | amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0024630_28 | PHROG | phrog_435 | endolysin | lysis |
| UHGV-0024630_28 | UniRef90 | UniRef90_UPI0019804B22 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0024630_28 | eggNOG-mapper | 33035.JPJF01000090_gene96 | Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase | NA |
| UHGV-0024630_28 | Pfam | PF01520 | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
| UHGV-0024630_28 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0024630_28 | Structural annotation | PF01520, PF18342, MF_00417, TIGR02883, COG0860, COG4991 | NA | NA |
| UHGV-0024630_31 | PHROG | phrog_13518 | NA | unknown function |
| UHGV-0024630_34 | KOfam | K10421 | CLIP1, RSN; CAP-Gly domain-containing linker protein 1 | NA |
| UHGV-0024630_34 | PHROG | phrog_4211 | tail length tape measure protein | tail |
| UHGV-0024630_34 | UniRef90 | UniRef90_A0A345BQ07 | Tail tape protein | NA |
| UHGV-0024630_34 | eggNOG-mapper | 1274524.BSONL12_21499 | COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) | NA |
| UHGV-0024630_34 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0024630_34 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0024630_34 | COG | COG0739 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain | NA |
| UHGV-0024630_35 | PHROG | phrog_30570 | NA | unknown function |
| UHGV-0024630_38 | PHROG | phrog_2729 | virion structural protein | head and packaging |
| UHGV-0024630_38 | UniRef90 | UniRef90_A0A345BPW2 | Putative structural protein | NA |
| UHGV-0024630_38 | eggNOG-mapper | 1163671.JAGI01000002_gene1222 | NA | NA |
| UHGV-0024630_39 | PHROG | phrog_4645 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_39 | UniRef90 | UniRef90_A0A7X9E0I2 | DOD-type homing endonuclease domain-containing protein | NA |
| UHGV-0024630_39 | eggNOG-mapper | 198094.BA_2689 | LAGLIDADG-like domain | NA |
| UHGV-0024630_39 | Pfam | PF14528 | LAGLIDADG-like domain | LAGLIDADG_3 |
| UHGV-0024630_39 | COG | COG1372 | Intein/homing endonuclease | NA |
| UHGV-0024630_39 | Structural annotation | PF05203, TIGR00647, COG1372 | NA | NA |
| UHGV-0024630_40 | PHROG | phrog_4051 | NA | unknown function |
| UHGV-0024630_41 | PHROG | phrog_6123 | virion structural protein | head and packaging |
| UHGV-0024630_41 | Structural annotation | PF06141 | NA | NA |
| UHGV-0024630_42 | UniRef90 | UniRef90_A0A345BPV9 | Ig domain protein | NA |
| UHGV-0024630_42 | Structural annotation | PF19408, PF11649, NF041894, COG5614 | NA | NA |
| UHGV-0024630_43 | Structural annotation | PF14276 | NA | NA |
| UHGV-0024630_44 | PHROG | phrog_3853 | NA | unknown function |
| UHGV-0024630_45 | PHROG | phrog_30998 | NA | unknown function |
| UHGV-0024630_46 | PHROG | phrog_4088 | NA | unknown function |
| UHGV-0024630_46 | UniRef90 | UniRef90_A0A1E1VIH8 | Conserved domain protein | NA |
| UHGV-0024630_46 | eggNOG-mapper | 1541960.KQ78_01850 | NA | NA |
| UHGV-0024630_46 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0024630_47 | PHROG | phrog_35301 | NA | unknown function |
| UHGV-0024630_48 | PHROG | phrog_3313 | NA | unknown function |
| UHGV-0024630_48 | eggNOG-mapper | 1304866.K413DRAFT_4735 | NA | NA |
| UHGV-0024630_48 | Structural annotation | PF09979, TIGR01543, COG3566 | NA | NA |
| UHGV-0024630_49 | PHROG | phrog_2739 | portal protein | head and packaging |
| UHGV-0024630_49 | UniRef90 | UniRef90_A0A345BPV2 | Putative portal protein | NA |
| UHGV-0024630_49 | eggNOG-mapper | 1308863.U5J9V5_9CAUD | NA | NA |
| UHGV-0024630_49 | Structural annotation | PF05133, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0024630_50 | PHROG | phrog_9084 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_50 | eggNOG-mapper | 397291.C804_06294 | transposase activity | NA |
| UHGV-0024630_50 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-0024630_50 | Structural annotation | PF18741, MF_04160, NF007294, COG2852 | NA | NA |
| UHGV-0024630_51 | PHROG | phrog_24618 | NA | unknown function |
| UHGV-0024630_51 | UniRef90 | UniRef90_A0A0H3V0N0 | Putative terminase large subunit | NA |
| UHGV-0024630_51 | eggNOG-mapper | 1308863.U5J9B2_9CAUD | NA | NA |
| UHGV-0024630_51 | Structural annotation | PF20441, MF_04146, TIGR01547, COG4373 | NA | NA |
| UHGV-0024630_52 | PHROG | phrog_559 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_52 | UniRef90 | UniRef90_A0A345AP20 | VSR homing endonuclease | NA |
| UHGV-0024630_52 | eggNOG-mapper | 315730.BcerKBAB4_1173 | Restriction endonuclease | NA |
| UHGV-0024630_52 | Pfam | PF05265 | NA | DUF723 |
| UHGV-0024630_52 | COG | COG3440 | Predicted restriction endonuclease | NA |
| UHGV-0024630_52 | Structural annotation | PF04480, PF05265, NF007294, COG3727 | NA | NA |
| UHGV-0024630_53 | PHROG | phrog_3314 | NA | unknown function |
| UHGV-0024630_53 | eggNOG-mapper | 1308863.U5J9N3_9CAUD | NA | NA |
| UHGV-0024630_54 | PHROG | phrog_5767 | sigma factor | transcription regulation |
| UHGV-0024630_54 | UniRef90 | UniRef90_A0A345BPU6 | HTH DNA binding domain protein | NA |
| UHGV-0024630_54 | eggNOG-mapper | 1123239.KB898628_gene3218 | NA | NA |
| UHGV-0024630_56 | PHROG | phrog_2245 | nucleoside triphosphate pyrophosphohydrolase | other |
| UHGV-0024630_56 | UniRef90 | UniRef90_A0A6I0VB33 | MazG domain-containing protein | NA |
| UHGV-0024630_56 | eggNOG-mapper | 1680.BADO_1259 | NA | NA |
| UHGV-0024630_66 | Structural annotation | PF00679, MF_01515, NF003194, COG4843 | NA | NA |
| UHGV-0024630_69 | PHROG | phrog_20187 | NA | unknown function |
| UHGV-0024630_69 | Structural annotation | PF16473, MF_00045, TIGR01406, COG5018 | NA | NA |
| UHGV-0024630_70 | Structural annotation | PF11019, MF_01022, NF003937, COG4502 | NA | NA |
| UHGV-0024630_72 | Pfam | PF13412 | Winged helix-turn-helix DNA-binding | HTH_24 |
| UHGV-0024630_72 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |
| UHGV-0024630_76 | Structural annotation | PF01541, MF_01029 | NA | NA |
| UHGV-0024630_79 | Structural annotation | MF_00040 | NA | NA |
| UHGV-0024630_81 | Pfam | PF11570 | Coiled-coil receptor-binding R-domain of colicin E2 | E2R135 |
| UHGV-0024630_101 | KOfam | K01491 | folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] | NA |
| UHGV-0024630_101 | PHROG | phrog_7320 | tetrahydrofolate dehydrogenase and cyclohydrolase | other |
| UHGV-0024630_101 | UniRef90 | UniRef90_A0A7C6HI38 | Bifunctional protein FolD | NA |
| UHGV-0024630_101 | eggNOG-mapper | 1232446.BAIE02000055_gene3020 | Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate | NA |
| UHGV-0024630_101 | Pfam | PF00763 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain | THF_DHG_CYH |
| UHGV-0024630_101 | Pfam | PF02882 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain | THF_DHG_CYH_C |
| UHGV-0024630_101 | COG | COG0190 | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | NA |
| UHGV-0024630_101 | HAMAP | MF_01576 | Bifunctional protein FolD [folD] | NA |
| UHGV-0024630_101 | Structural annotation | PF02882, PF00763, MF_01576, NF010775, COG0190 | NA | NA |
| UHGV-0024630_103 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-0024630_103 | UniRef90 | UniRef90_A0A843FNF2 | Metallophosphoesterase | NA |
| UHGV-0024630_103 | eggNOG-mapper | 1410632.JHWW01000019_gene1481 | NA | NA |
| UHGV-0024630_103 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0024630_103 | Structural annotation | MF_00575, TIGR04123, COG4186 | NA | NA |
| UHGV-0024630_104 | Structural annotation | PF06315 | NA | NA |
| UHGV-0024630_107 | Structural annotation | PF02581, MF_02232, TIGR01182, COG0135 | NA | NA |
| UHGV-0024630_114 | UniRef90 | UniRef90_A0A5F0K0X9 | NA | NA |
| UHGV-0024630_114 | eggNOG-mapper | 1403948.Q618_VCMC00001G1448 | NA | NA |
| UHGV-0024630_115 | KOfam | K03086 | rpoD; RNA polymerase primary sigma factor | NA |
| UHGV-0024630_115 | PHROG | phrog_351 | RNA polymerase sigma factor | transcription regulation |
| UHGV-0024630_115 | UniRef90 | UniRef90_A0A4R3KRI1 | RNA polymerase sigma factor SigA | NA |
| UHGV-0024630_115 | eggNOG-mapper | 1321779.HMPREF1984_00236 | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth | NA |
| UHGV-0024630_115 | PADLOC | MzaA_00001 | NA | mzaABCDE |
| UHGV-0024630_115 | Pfam | PF00140 | Sigma-70 factor, region 1.2 | Sigma70_r1_2 |
| UHGV-0024630_115 | Pfam | PF04542 | Sigma-70 region 2 | Sigma70_r2 |
| UHGV-0024630_115 | Pfam | PF04539 | Sigma-70 region 3 | Sigma70_r3 |
| UHGV-0024630_115 | Pfam | PF04545 | Sigma-70, region 4 | Sigma70_r4 |
| UHGV-0024630_115 | NCBIFam | TIGR02937.1 | sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-0024630_115 | COG | COG0568 | DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) | NA |
| UHGV-0024630_115 | Structural annotation | PF04542, PF04539, MF_00959, NF005920, COG0568 | NA | NA |
| UHGV-0024630_118 | PHROG | phrog_5018 | NA | unknown function |
| UHGV-0024630_118 | UniRef90 | UniRef90_UPI0019169841 | group I intron-associated PD-(D/E)XK endonuclease | NA |
| UHGV-0024630_118 | Pfam | PF11645 | PD-(D/E)XK endonuclease | PDDEXK_5 |
| UHGV-0024630_118 | Structural annotation | PF11645, MF_01490, NF011271, COG4815 | NA | NA |
| UHGV-0024630_119 | UniRef90 | UniRef90_UPI0015FAF575 | polya polymerase | NA |
| UHGV-0024630_119 | eggNOG-mapper | 693746.OBV_21470 | NA | NA |
| UHGV-0024630_119 | Structural annotation | NF008146, COG1925 | NA | NA |
| UHGV-0024630_120 | PHROG | phrog_5018 | NA | unknown function |
| UHGV-0024630_120 | UniRef90 | UniRef90_A0A288TXW0 | PDDEXK_5 domain-containing protein | NA |
| UHGV-0024630_120 | eggNOG-mapper | 1227487.C474_10871 | NA | NA |
| UHGV-0024630_120 | PADLOC | HEase_00029 | homing endonuclease | RM |
| UHGV-0024630_120 | Pfam | PF11645 | PD-(D/E)XK endonuclease | PDDEXK_5 |
| UHGV-0024630_120 | Structural annotation | PF11645, MF_01490, NF011271, COG4815 | NA | NA |
| UHGV-0024630_121 | PHROG | phrog_35854 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_121 | UniRef90 | UniRef90_UPI001C60FFF6 | HNH endonuclease | NA |
| UHGV-0024630_121 | eggNOG-mapper | 553174.HMPREF0659_A7222 | HNH nucleases | NA |
| UHGV-0024630_121 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0024630_123 | Structural annotation | PF18414 | NA | NA |
| UHGV-0024630_126 | PHROG | phrog_1479 | NA | unknown function |
| UHGV-0024630_126 | eggNOG-mapper | 1256908.HMPREF0373_01589 | NA | NA |
| UHGV-0024630_126 | Pfam | PF20274 | Cyclic-phosphate processing Receiver domain | cREC_REC |
| UHGV-0024630_126 | Structural annotation | PF20274, NF033791, COG4567 | NA | NA |
| UHGV-0024630_127 | PHROG | phrog_850 | RNA-binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_127 | UniRef90 | UniRef90_A0A843FJC6 | NA | NA |
| UHGV-0024630_127 | eggNOG-mapper | 1541960.KQ78_01972 | oxidoreductase activity | NA |
| UHGV-0024630_127 | Pfam | PF11443 | NA | DUF2828 |
| UHGV-0024630_127 | COG | COG2304 | Secreted protein containing bacterial Ig-like domain and vWFA domain | NA |
| UHGV-0024630_127 | Structural annotation | PF11443, MF_01340, COG2304 | NA | NA |
| UHGV-0024630_128 | KOfam | K06236 | COL1A; collagen type I alpha | NA |
| UHGV-0024630_128 | PHROG | phrog_819 | tail protein | tail |
| UHGV-0024630_128 | eggNOG-mapper | 290402.Cbei_3387 | NA | NA |
| UHGV-0024630_128 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | Collagen |
| UHGV-0024630_130 | PHROG | phrog_13126 | beta-1,4-glycosyltransferase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0024630_130 | UniRef90 | UniRef90_UPI0013799F0A | glycosyltransferase | NA |
| UHGV-0024630_130 | eggNOG-mapper | 1378168.N510_02827 | Glycosyl transferase, family 2 | NA |
| UHGV-0024630_130 | Pfam | PF13704 | Glycosyl transferase family 2 | Glyco_tranf_2_4 |
| UHGV-0024630_130 | Pfam | PF07719 | Tetratricopeptide repeat | TPR_2 |
| UHGV-0024630_130 | COG | COG0463 | Glycosyltransferase involved in cell wall bisynthesis | NA |
| UHGV-0024630_130 | Structural annotation | PF18768, PF13641, MF_00994, MF_00316, TIGR04195, COG0457, COG0463 | NA | NA |
| UHGV-0024630_132 | eggNOG-mapper | 742742.HMPREF9452_01288 | NA | NA |
| UHGV-0024630_134 | Structural annotation | PF21621 | NA | NA |
| UHGV-0024630_135 | Structural annotation | PF10127, PF08222, MF_00621, TIGR02787, NF000079, COG4465, COG3541 | NA | NA |
| UHGV-0024630_136 | KOfam | K07074 | NA | NA |
| UHGV-0024630_136 | PHROG | phrog_388 | nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_136 | UniRef90 | UniRef90_A0A8D9UHX4 | RNA repair pathway DNA polymerase beta family | NA |
| UHGV-0024630_136 | Pfam | PF10127 | RNA repair pathway DNA polymerase beta family | RlaP |
| UHGV-0024630_136 | Structural annotation | PF10127, NF000079, COG3541 | NA | NA |
| UHGV-0024630_137 | KOfam | K18962 | rnlB; T4 RNA ligase 2 [EC:6.5.1.3] | NA |
| UHGV-0024630_137 | PHROG | phrog_968 | RNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_137 | UniRef90 | UniRef90_A0A843GTM3 | RNA_ligase domain-containing protein | NA |
| UHGV-0024630_137 | eggNOG-mapper | 1122176.KB903554_gene3905 | RNA ligase | NA |
| UHGV-0024630_137 | Pfam | PF21189 | PHA02142 OB-fold domain | PHA02142 |
| UHGV-0024630_137 | Pfam | PF09414 | RNA ligase | RNA_ligase |
| UHGV-0024630_137 | COG | COG0073 | tRNA-binding EMAP/Myf domain | NA |
| UHGV-0024630_137 | Structural annotation | PF21189, PF09511, MF_04150, TIGR02306, COG1423, COG0073 | NA | NA |
| UHGV-0024630_138 | PHROG | phrog_1257 | ribosome associated inhibitor A; zinc finger domain | moron, auxiliary metabolic gene and host takeover |
| UHGV-0024630_138 | UniRef90 | UniRef90_A0A345BPS6 | Ribosome associated inhibitor A | NA |
| UHGV-0024630_139 | KOfam | K08073 | PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] | NA |
| UHGV-0024630_139 | PHROG | phrog_6931 | NA | unknown function |
| UHGV-0024630_139 | UniRef90 | UniRef90_A0A4R2JLV7 | Putative kinase | NA |
| UHGV-0024630_139 | eggNOG-mapper | 1220589.CD32_13550 | Chromatin associated protein KTI12 | NA |
| UHGV-0024630_139 | Pfam | PF13671 | AAA domain | AAA_33 |
| UHGV-0024630_139 | COG | COG2844 | UTP:GlnB (protein PII) uridylyltransferase | NA |
| UHGV-0024630_139 | Structural annotation | PF13671, MF_03172, TIGR03574, COG4639 | NA | NA |
| UHGV-0024630_140 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-0024630_140 | UniRef90 | UniRef90_A0A843GVP8 | Metallophosphoesterase family protein | NA |
| UHGV-0024630_140 | eggNOG-mapper | 1392491.JIAE01000001_gene1129 | Calcineurin-like phosphoesterase | NA |
| UHGV-0024630_140 | Pfam | PF12850 | Calcineurin-like phosphoesterase superfamily domain | Metallophos_2 |
| UHGV-0024630_140 | COG | COG4186 | NA | NA |
| UHGV-0024630_140 | Structural annotation | NF006988, COG4186 | NA | NA |
| UHGV-0024630_143 | KOfam | K07175 | phoH2; PhoH-like ATPase | NA |
| UHGV-0024630_143 | PHROG | phrog_2765 | PhoH-like phosphate starvation-inducible | other |
| UHGV-0024630_143 | UniRef90 | UniRef90_UPI000773FF09 | PhoH family protein | NA |
| UHGV-0024630_143 | eggNOG-mapper | 1123252.ATZF01000010_gene420 | PIN domain | NA |
| UHGV-0024630_143 | Pfam | PF13638 | PIN domain | PIN_4 |
| UHGV-0024630_143 | Pfam | PF02562 | PhoH-like protein | PhoH |
| UHGV-0024630_143 | COG | COG1875 | Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains | NA |
| UHGV-0024630_143 | Structural annotation | PF02562, PF13638, PF09142, MF_00265, NF007827, NF009148, COG1875 | NA | NA |
| UHGV-0024630_145 | PHROG | phrog_36029 | NA | unknown function |
| UHGV-0024630_145 | UniRef90 | UniRef90_A0A345BPS8 | Holin of superfamily 6 | NA |
| UHGV-0024630_145 | eggNOG-mapper | 411468.CLOSCI_01511 | NA | NA |
| UHGV-0024630_145 | Structural annotation | PF09682 | NA | NA |
| UHGV-0024630_146 | KOfam | K02470 | gyrB; DNA gyrase subunit B [EC:5.6.2.2] | NA |
| UHGV-0024630_146 | PHROG | phrog_543 | DNA topoisomerase II large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_146 | UniRef90 | UniRef90_A0A3B9Z7X0 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0024630_146 | eggNOG-mapper | 546271.Selsp_0007 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0024630_146 | Pfam | PF00204 | DNA gyrase B | DNA_gyraseB |
| UHGV-0024630_146 | Pfam | PF01751 | Toprim domain | Toprim |
| UHGV-0024630_146 | COG | COG0187 | DNA gyrase/topoisomerase IV, subunit B | NA |
| UHGV-0024630_146 | Structural annotation | PF00204, MF_01898, NF004189, COG0187 | NA | NA |
| UHGV-0024630_147 | KOfam | K02470 | gyrB; DNA gyrase subunit B [EC:5.6.2.2] | NA |
| UHGV-0024630_147 | PHROG | phrog_543 | DNA topoisomerase II large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_147 | UniRef90 | UniRef90_A0A3D6ADH1 | DNA topoisomerase (ATP-hydrolyzing) (Fragment) | NA |
| UHGV-0024630_147 | eggNOG-mapper | 1408321.JNJD01000006_gene686 | TopoisomeraseII | NA |
| UHGV-0024630_147 | Pfam | PF00986 | DNA gyrase B subunit, carboxyl terminus | DNA_gyraseB_C |
| UHGV-0024630_147 | COG | COG0187 | DNA gyrase/topoisomerase IV, subunit B | NA |
| UHGV-0024630_147 | Structural annotation | PF00986 | NA | NA |
| UHGV-0024630_148 | KOfam | K02469 | gyrA; DNA gyrase subunit A [EC:5.6.2.2] | NA |
| UHGV-0024630_148 | PHROG | phrog_551 | DNA topoisomerase II | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_148 | UniRef90 | UniRef90_A0A832SNJ2 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0024630_148 | eggNOG-mapper | 1541960.KQ78_01979 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0024630_148 | Pfam | PF00521 | DNA gyrase/topoisomerase IV, subunit A | DNA_topoisoIV |
| UHGV-0024630_148 | Pfam | PF03989 | DNA gyrase C-terminal domain, beta-propeller | DNA_gyraseA_C |
| UHGV-0024630_148 | COG | COG0188 | DNA gyrase/topoisomerase IV, subunit A | NA |
| UHGV-0024630_148 | Structural annotation | PF00521, PF03989, MF_01897, NF004043, COG0188 | NA | NA |
| UHGV-0024630_149 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-0024630_149 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_149 | UniRef90 | UniRef90_A0A843FST5 | DNA ligase | NA |
| UHGV-0024630_149 | eggNOG-mapper | 411470.RUMGNA_00017 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-0024630_149 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-0024630_149 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-0024630_149 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-0024630_149 | NCBIFam | NF005932.1 | NAD-dependent DNA ligase LigA | NA |
| UHGV-0024630_149 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0024630_149 | HAMAP | MF_01588 | DNA ligase [ligA] | NA |
| UHGV-0024630_149 | Structural annotation | PF01653, PF03120, PF00533, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-0024630_151 | UniRef90 | UniRef90_A0A345BPT3 | SarR-like protein | NA |
| UHGV-0024630_151 | Structural annotation | PF04182, MF_01909, NF040939, COG1675 | NA | NA |
| UHGV-0024630_152 | PHROG | phrog_314 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_152 | UniRef90 | UniRef90_A0A843GN52 | GIY-YIG nuclease family protein | NA |
| UHGV-0024630_152 | eggNOG-mapper | 1129368.SMIPMB4A_v3c4190 | GIY-YIG catalytic domain | NA |
| UHGV-0024630_152 | PADLOC | HEase_00030 | homing endonuclease | RM |
| UHGV-0024630_152 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0024630_152 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0024630_152 | Structural annotation | PF19835, TIGR01453 | NA | NA |
| UHGV-0024630_153 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0024630_153 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_153 | UniRef90 | UniRef90_A0A7X2NTD7 | FAD-dependent thymidylate synthase | NA |
| UHGV-0024630_153 | eggNOG-mapper | 1282887.AUJG01000001_gene1906 | thymidylate synthase (FAD) activity | NA |
| UHGV-0024630_153 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0024630_153 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0024630_153 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0024630_154 | UniRef90 | UniRef90_A0A345BPT4 | LexA repressor | NA |
| UHGV-0024630_154 | Structural annotation | PF03444, MF_00732, TIGR02337, COG1321 | NA | NA |
| UHGV-0024630_155 | PHROG | phrog_2367 | NA | unknown function |
| UHGV-0024630_155 | Structural annotation | PF00436, PF19649, MF_00984, NF004476, COG2965 | NA | NA |
| UHGV-0024630_156 | PHROG | phrog_124 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_156 | UniRef90 | UniRef90_A0A832SVD6 | ATP-binding protein | NA |
| UHGV-0024630_156 | eggNOG-mapper | 1541960.KQ78_01919 | Belongs to the helicase family. UvrD subfamily | NA |
| UHGV-0024630_156 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-0024630_156 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-0024630_156 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-0024630_157 | PHROG | phrog_4680 | NA | unknown function |
| UHGV-0024630_158 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0024630_158 | PHROG | phrog_19299 | terminase large subunit | head and packaging |
| UHGV-0024630_158 | UniRef90 | UniRef90_A0A173ZX51 | Replicative DNA helicase | NA |
| UHGV-0024630_158 | eggNOG-mapper | 537007.BLAHAN_05495 | DnaB-like helicase C terminal domain | NA |
| UHGV-0024630_158 | Pfam | PF14528 | LAGLIDADG-like domain | LAGLIDADG_3 |
| UHGV-0024630_158 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0024630_158 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0024630_159 | KOfam | K02316 | dnaG; DNA primase [EC:2.7.7.101] | NA |
| UHGV-0024630_159 | PHROG | phrog_47 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_159 | UniRef90 | UniRef90_A0A345BPU0 | DNA primase | NA |
| UHGV-0024630_159 | eggNOG-mapper | 224308.BSU20360 | DNA primase activity | NA |
| UHGV-0024630_159 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0024630_159 | Structural annotation | PF01807, PF19898, MF_00974, NF006382, COG0358 | NA | NA |
| UHGV-0024630_161 | KOfam | K07462 | recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] | NA |
| UHGV-0024630_161 | PHROG | phrog_2484 | RecJ-like ssDNA exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0024630_161 | UniRef90 | UniRef90_A0A843GQK3 | DHH family phosphoesterase | NA |
| UHGV-0024630_161 | eggNOG-mapper | 224308.BSU20350 | Single-stranded-DNA-specific exonuclease RecJ | NA |
| UHGV-0024630_161 | Pfam | PF01368 | DHH family | DHH |
| UHGV-0024630_161 | COG | COG0608 | ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation | NA |
| UHGV-0024630_161 | Structural annotation | PF17768, PF02272, MF_00207, TIGR00644, COG0608 | NA | NA |