| UHGV-1373868_1 | eggNOG-mapper | 742733.HMPREF9469_01838 | sulfate reduction | NA |
| UHGV-1373868_1 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1373868_3 | UniRef90 | UniRef90_A0A317UED7 | Restriction alleviation protein, Lar family | NA |
| UHGV-1373868_3 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-1373868_3 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-1373868_4 | PHROG | phrog_20593 | NA | unknown function |
| UHGV-1373868_5 | Structural annotation | PF06107, COG4481 | NA | NA |
| UHGV-1373868_10 | PHROG | phrog_10714 | NA | unknown function |
| UHGV-1373868_10 | eggNOG-mapper | 537007.BLAHAN_05460 | NA | NA |
| UHGV-1373868_12 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-1373868_12 | PHROG | phrog_3717 | terminase large subunit | head and packaging |
| UHGV-1373868_12 | UniRef90 | UniRef90_A0A412EKJ9 | PBSX family phage terminase large subunit | NA |
| UHGV-1373868_12 | eggNOG-mapper | 33035.JPJF01000106_gene3136 | Terminase small subunit | NA |
| UHGV-1373868_12 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-1373868_12 | Pfam | PF04466 | Phage terminase large subunit | Terminase_3 |
| UHGV-1373868_12 | Pfam | PF17288 | Terminase RNAseH like domain | Terminase_3C |
| UHGV-1373868_12 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-1373868_12 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-1373868_12 | Structural annotation | PF04466, PF17288, PF03592, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1373868_13 | eggNOG-mapper | 411473.RUMCAL_02525 | NA | NA |
| UHGV-1373868_14 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-1373868_14 | UniRef90 | UniRef90_A0A1C6CDM8 | Phage portal protein, putative, A118 family | NA |
| UHGV-1373868_14 | eggNOG-mapper | 33035.JPJF01000106_gene3135 | phage minor capsid protein | NA |
| UHGV-1373868_14 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-1373868_15 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-1373868_15 | UniRef90 | UniRef90_A0A395X791 | Phage capsid protein | NA |
| UHGV-1373868_15 | eggNOG-mapper | 476272.RUMHYD_01761 | Phage minor capsid protein 2 | NA |
| UHGV-1373868_15 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-1373868_15 | COG | COG2369 | NA | NA |
| UHGV-1373868_15 | Structural annotation | PF06152 | NA | NA |
| UHGV-1373868_16 | PHROG | phrog_3754 | NA | unknown function |
| UHGV-1373868_16 | eggNOG-mapper | 476272.RUMHYD_01764 | NA | NA |
| UHGV-1373868_17 | UniRef90 | UniRef90_A0A395X7A4 | CTP synthase | NA |
| UHGV-1373868_17 | eggNOG-mapper | 476272.RUMHYD_01766 | NA | NA |
| UHGV-1373868_18 | UniRef90 | UniRef90_A0A1C5PJW7 | Putative zinc finger/helix-turn-helix protein, YgiT family | NA |
| UHGV-1373868_18 | eggNOG-mapper | 1410625.JHWK01000002_gene45 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-1373868_18 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1373868_18 | COG | COG2944 | DNA-binding transcriptional regulator YiaG, XRE-type HTH domain | NA |
| UHGV-1373868_18 | Structural annotation | PF01381, NF040522, COG2944 | NA | NA |
| UHGV-1373868_20 | eggNOG-mapper | 411470.RUMGNA_03785 | NA | NA |
| UHGV-1373868_20 | AcrCatalog | cluster_32378 | NA | NA |
| UHGV-1373868_21 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-1373868_21 | eggNOG-mapper | 476272.RUMHYD_01768 | NA | NA |
| UHGV-1373868_22 | PHROG | phrog_22984 | NA | unknown function |
| UHGV-1373868_23 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1373868_23 | eggNOG-mapper | 397290.C810_01328 | NA | NA |
| UHGV-1373868_24 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-1373868_24 | UniRef90 | UniRef90_A0A285PT46 | Tumour necrosis factor-like domain | NA |
| UHGV-1373868_24 | eggNOG-mapper | 397290.C810_05214 | NA | NA |
| UHGV-1373868_24 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-1373868_25 | PHROG | phrog_28802 | NA | unknown function |
| UHGV-1373868_25 | eggNOG-mapper | 476272.RUMHYD_01772 | NA | NA |
| UHGV-1373868_26 | PHROG | phrog_194 | head scaffolding protein | head and packaging |
| UHGV-1373868_26 | UniRef90 | UniRef90_UPI001D14C9C8 | phage scaffolding protein | NA |
| UHGV-1373868_26 | eggNOG-mapper | 476272.RUMHYD_01775 | COG NOG36366 non supervised orthologous group | NA |
| UHGV-1373868_26 | Pfam | PF06810 | Phage minor structural protein GP20 | Phage_GP20 |
| UHGV-1373868_27 | PHROG | phrog_544 | major head protein | head and packaging |
| UHGV-1373868_27 | UniRef90 | UniRef90_A0A395X7A1 | S-l_SbsC_C domain-containing protein | NA |
| UHGV-1373868_27 | eggNOG-mapper | 1232453.BAIF02000011_gene3359 | NA | NA |
| UHGV-1373868_27 | Pfam | PF18316 | S-layer protein SbsC C-terminal domain | S-l_SbsC_C |
| UHGV-1373868_27 | Structural annotation | PF03864, PF18316, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-1373868_28 | PHROG | phrog_541 | head-tail adaptor | connector |
| UHGV-1373868_28 | eggNOG-mapper | 476272.RUMHYD_01778 | NA | NA |
| UHGV-1373868_30 | PHROG | phrog_1129 | holin | lysis |
| UHGV-1373868_30 | UniRef90 | UniRef90_A0A395X7B2 | Enolase | NA |
| UHGV-1373868_30 | eggNOG-mapper | 411461.DORFOR_00721 | NA | NA |
| UHGV-1373868_30 | Pfam | PF16079 | Phage holin family Hol44, in holin superfamily V | Phage_holin_5_2 |
| UHGV-1373868_30 | Structural annotation | PF06946 | NA | NA |
| UHGV-1373868_31 | PHROG | phrog_3366 | NA | unknown function |
| UHGV-1373868_31 | eggNOG-mapper | 476272.RUMHYD_01779 | NA | NA |
| UHGV-1373868_31 | Structural annotation | PF20536, COG5614 | NA | NA |
| UHGV-1373868_32 | PHROG | phrog_556 | minor head protein | head and packaging |
| UHGV-1373868_32 | UniRef90 | UniRef90_UPI000E4989EB | minor capsid protein | NA |
| UHGV-1373868_32 | eggNOG-mapper | 476272.RUMHYD_01780 | NA | NA |
| UHGV-1373868_32 | Pfam | PF11114 | Minor capsid protein | Minor_capsid_2 |
| UHGV-1373868_32 | Structural annotation | PF11114 | NA | NA |
| UHGV-1373868_33 | PHROG | phrog_3266 | tail completion | connector |
| UHGV-1373868_33 | eggNOG-mapper | 476272.RUMHYD_01781 | NA | NA |
| UHGV-1373868_33 | Structural annotation | PF12691 | NA | NA |
| UHGV-1373868_34 | PHROG | phrog_3099 | NA | unknown function |
| UHGV-1373868_34 | eggNOG-mapper | 411902.CLOBOL_00129 | NA | NA |
| UHGV-1373868_34 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-1373868_35 | PHROG | phrog_11299 | NA | unknown function |
| UHGV-1373868_35 | eggNOG-mapper | 33035.JPJF01000106_gene3125 | NA | NA |
| UHGV-1373868_35 | Structural annotation | PF10666 | NA | NA |
| UHGV-1373868_36 | PHROG | phrog_706 | NA | unknown function |
| UHGV-1373868_36 | UniRef90 | UniRef90_UPI001BAD00AD | Gp15 family bacteriophage protein | NA |
| UHGV-1373868_36 | eggNOG-mapper | 411459.RUMOBE_01383 | Bacteriophage Gp15 protein | NA |
| UHGV-1373868_36 | Pfam | PF06854 | Bacteriophage Gp15 protein | Phage_Gp15 |
| UHGV-1373868_36 | Structural annotation | PF06854 | NA | NA |
| UHGV-1373868_37 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-1373868_37 | UniRef90 | UniRef90_A0A1C5PIN9 | Phage-related protein | NA |
| UHGV-1373868_37 | eggNOG-mapper | 476272.RUMHYD_01785 | phage tail tape measure protein | NA |
| UHGV-1373868_37 | COG | COG1511 | NA | NA |
| UHGV-1373868_37 | Structural annotation | PF20155, TIGR01760, COG3941 | NA | NA |
| UHGV-1373868_38 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-1373868_38 | eggNOG-mapper | 483218.BACPEC_01144 | NA | NA |
| UHGV-1373868_38 | Pfam | PF20458 | NA | DUF6711 |
| UHGV-1373868_38 | Structural annotation | PF20458, TIGR01633, COG3499 | NA | NA |
| UHGV-1373868_39 | PHROG | phrog_18190 | NA | unknown function |
| UHGV-1373868_39 | UniRef90 | UniRef90_UPI000E4C0A8F | bacterial Ig-like domain-containing protein | NA |
| UHGV-1373868_39 | eggNOG-mapper | 428125.CLOLEP_00457 | endo-1,4-beta-xylanase activity | NA |
| UHGV-1373868_39 | Pfam | PF13306 | BspA type Leucine rich repeat region (6 copies) | LRR_5 |
| UHGV-1373868_39 | Pfam | PF07523 | Bacterial Ig-like domain (group 3) | Big_3 |
| UHGV-1373868_39 | COG | COG0683 | ABC-type branched-chain amino acid transport system, periplasmic component | NA |
| UHGV-1373868_39 | Structural annotation | PF13306, PF07523, PF05113, NF033848, NF040978, COG3500 | NA | NA |
| UHGV-1373868_41 | UniRef90 | UniRef90_A0A6L5T7F3 | NA | NA |
| UHGV-1373868_41 | eggNOG-mapper | 479437.Elen_2641 | NA | NA |
| UHGV-1373868_41 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-1373868_41 | Structural annotation | PF19789 | NA | NA |
| UHGV-1373868_42 | UniRef90 | UniRef90_R7NA43 | ATP synthase B chain | NA |
| UHGV-1373868_43 | PHROG | phrog_9589 | endolysin | lysis |
| UHGV-1373868_43 | UniRef90 | UniRef90_A0A6N9LGV5 | CHAP domain-containing protein | NA |
| UHGV-1373868_43 | eggNOG-mapper | 1123075.AUDP01000020_gene1533 | pathogenesis | NA |
| UHGV-1373868_43 | Pfam | PF05257 | CHAP domain | CHAP |
| UHGV-1373868_43 | COG | COG3942 | Surface antigen | NA |
| UHGV-1373868_43 | Structural annotation | PF08230, PF19087 | NA | NA |
| UHGV-1373868_44 | KOfam | K14059 | int; integrase | NA |
| UHGV-1373868_44 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1373868_44 | UniRef90 | UniRef90_A0A6L8SXX0 | Tyrosine-type recombinase/integrase | NA |
| UHGV-1373868_44 | eggNOG-mapper | 1235798.C817_04751 | Belongs to the 'phage' integrase family | NA |
| UHGV-1373868_44 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1373868_44 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1373868_44 | Structural annotation | PF00589, MF_01808, TIGR02224, COG4974 | NA | NA |
| UHGV-1373868_45 | PHROG | phrog_8545 | superinfection exclusion Sie-like | moron, auxiliary metabolic gene and host takeover |
| UHGV-1373868_45 | UniRef90 | UniRef90_UPI001C0EAFDF | OB-fold putative lipoprotein | NA |
| UHGV-1373868_45 | eggNOG-mapper | 1304866.K413DRAFT_0836 | tRNA_anti-like | NA |
| UHGV-1373868_45 | Pfam | PF12869 | tRNA_anti-like | tRNA_anti-like |
| UHGV-1373868_45 | Structural annotation | PF12869, PF10571, MF_01959, TIGR03943, COG5235 | NA | NA |
| UHGV-1373868_47 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-1373868_47 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1373868_47 | UniRef90 | UniRef90_A0A395X7H2 | XRE family transcriptional regulator | NA |
| UHGV-1373868_47 | eggNOG-mapper | 397288.C806_00131 | Transcriptional | NA |
| UHGV-1373868_47 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1373868_47 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1373868_47 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1373868_47 | Structural annotation | PF01381, MF_02017, NF041951, COG3655 | NA | NA |
| UHGV-1373868_48 | UniRef90 | UniRef90_A0A395X814 | XRE family transcriptional regulator | NA |
| UHGV-1373868_48 | eggNOG-mapper | 1121289.JHVL01000079_gene1187 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-1373868_48 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1373868_48 | Structural annotation | PF12844, NF041951, COG1396 | NA | NA |
| UHGV-1373868_49 | Pfam | PF10544 | T5orf172 domain | T5orf172 |
| UHGV-1373868_49 | Structural annotation | PF10544 | NA | NA |
| UHGV-1373868_52 | PHROG | phrog_463 | anti-repressor | transcription regulation |
| UHGV-1373868_52 | UniRef90 | UniRef90_A0A3A6GZT3 | Phage repressor protein | NA |
| UHGV-1373868_52 | eggNOG-mapper | 411490.ANACAC_00813 | BRO family, N-terminal domain | NA |
| UHGV-1373868_52 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-1373868_52 | Pfam | PF10552 | ORF6C domain | ORF6C |
| UHGV-1373868_52 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-1373868_52 | Structural annotation | PF10552, PF02498, TIGR02681, COG3617 | NA | NA |
| UHGV-1373868_54 | PHROG | phrog_6058 | NA | unknown function |
| UHGV-1373868_54 | eggNOG-mapper | 742733.HMPREF9469_05094 | NA | NA |
| UHGV-1373868_55 | AcrCatalog | cluster_17974 | NA | NA |
| UHGV-1373868_59 | Structural annotation | NF011879 | NA | NA |
| UHGV-1373868_60 | UniRef90 | UniRef90_R6RDX0 | Arginyl-tRNA synthetase | NA |
| UHGV-1373868_61 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1373868_61 | UniRef90 | UniRef90_A0A679HLT5 | Essential recombination function protein | NA |
| UHGV-1373868_61 | eggNOG-mapper | 762982.HMPREF9442_00551 | Erf family | NA |
| UHGV-1373868_61 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-1373868_61 | Structural annotation | PF04404, TIGR00607, COG1978 | NA | NA |
| UHGV-1373868_62 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-1373868_62 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-1373868_62 | UniRef90 | UniRef90_A0A412ELG8 | Single-stranded DNA-binding protein | NA |
| UHGV-1373868_62 | eggNOG-mapper | 658655.HMPREF0988_02584 | Single-strand binding protein family | NA |
| UHGV-1373868_62 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-1373868_62 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-1373868_62 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-1373868_62 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-1373868_62 | Structural annotation | PF00436, MF_00984, NF005580, COG0629 | NA | NA |
| UHGV-1373868_63 | PHROG | phrog_3490 | ERCC4-type nuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1373868_63 | UniRef90 | UniRef90_A0A395XB48 | ERCC4 domain-containing protein | NA |
| UHGV-1373868_63 | eggNOG-mapper | 357809.Cphy_2986 | NA | NA |
| UHGV-1373868_63 | Pfam | PF02732 | ERCC4 domain | ERCC4 |
| UHGV-1373868_63 | Structural annotation | PF03834, NF040956, COG1948 | NA | NA |
| UHGV-1373868_64 | KOfam | K02316 | dnaG; DNA primase [EC:2.7.7.101] | NA |
| UHGV-1373868_64 | PHROG | phrog_11992 | NA | unknown function |
| UHGV-1373868_64 | UniRef90 | UniRef90_A0A412EM56 | DNA primase | NA |
| UHGV-1373868_64 | eggNOG-mapper | 476272.RUMHYD_01741 | CHC2 zinc finger | NA |
| UHGV-1373868_64 | PADLOC | drt-UG29 | DRT | DRT |
| UHGV-1373868_64 | Pfam | PF01807 | CHC2 zinc finger | zf-CHC2 |
| UHGV-1373868_64 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-1373868_64 | Structural annotation | PF01807, PF00401 | NA | NA |
| UHGV-1373868_65 | PHROG | phrog_8841 | DNA primase/helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1373868_65 | UniRef90 | UniRef90_A0A412EL97 | NA | NA |
| UHGV-1373868_65 | eggNOG-mapper | 476272.RUMHYD_01742 | NA | NA |
| UHGV-1373868_65 | Pfam | PF06048 | NA | DUF927 |
| UHGV-1373868_65 | Pfam | PF18662 | Cch helix turn helix domain | HTH_56 |
| UHGV-1373868_65 | COG | COG5519 | NA | NA |
| UHGV-1373868_65 | Structural annotation | PF06048, PF18662, MF_00016, NF011296, COG5519 | NA | NA |
| UHGV-1373868_66 | Structural annotation | NF010187 | NA | NA |
| UHGV-1373868_67 | UniRef90 | UniRef90_A0A6L8SWV5 | Winged helix-turn-helix transcriptional regulator | NA |
| UHGV-1373868_67 | Pfam | PF13412 | Winged helix-turn-helix DNA-binding | HTH_24 |
| UHGV-1373868_67 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-1373868_67 | Structural annotation | PF01726, COG0640 | NA | NA |
| UHGV-1373868_68 | PHROG | phrog_17690 | NA | unknown function |
| UHGV-1373868_68 | eggNOG-mapper | 476272.RUMHYD_03925 | NA | NA |
| UHGV-1373868_69 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1373868_69 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1373868_69 | UniRef90 | UniRef90_UPI000CF96674 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-1373868_69 | eggNOG-mapper | 1232452.BAIB02000007_gene1640 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1373868_69 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-1373868_69 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1373868_69 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1373868_69 | Structural annotation | PF01507, MF_00063, NF010369, COG0175 | NA | NA |
| UHGV-1373868_70 | eggNOG-mapper | 742733.HMPREF9469_01838 | sulfate reduction | NA |
| UHGV-1373868_70 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |