| UHGV-0004425_1 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-0004425_1 | UniRef90 | UniRef90_A0A3C0QMQ1 | NA | NA |
| UHGV-0004425_1 | eggNOG-mapper | 411473.RUMCAL_01927 | NA | NA |
| UHGV-0004425_1 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-0004425_1 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-0004425_1 | Structural annotation | PF11195 | NA | NA |
| UHGV-0004425_2 | PHROG | phrog_4105 | NA | unknown function |
| UHGV-0004425_2 | eggNOG-mapper | 33035.JPJF01000043_gene996 | NA | NA |
| UHGV-0004425_4 | PHROG | phrog_4492 | tail fiber protein | tail |
| UHGV-0004425_4 | eggNOG-mapper | 931276.Cspa_c07580 | nuclear chromosome segregation | NA |
| UHGV-0004425_4 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0004425_4 | Structural annotation | PF21621, PF21253, MF_01537, NF007875, COG3123 | NA | NA |
| UHGV-0004425_5 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-0004425_5 | eggNOG-mapper | 864178.E2ELJ7_9CAUD | NA | NA |
| UHGV-0004425_5 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-0004425_5 | Pfam | PF13306 | BspA type Leucine rich repeat region (6 copies) | LRR_5 |
| UHGV-0004425_6 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0004425_6 | UniRef90 | UniRef90_A0A1Q9PJB8 | Phage tail protein | NA |
| UHGV-0004425_6 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0004425_6 | Structural annotation | PF16774, PF20753, TIGR01633, COG4722 | NA | NA |
| UHGV-0004425_8 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-0004425_8 | UniRef90 | UniRef90_UPI000D10D8A8 | phage portal protein | NA |
| UHGV-0004425_8 | eggNOG-mapper | 1304866.K413DRAFT_1223 | Phage portal protein, HK97 family | NA |
| UHGV-0004425_8 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-0004425_8 | NCBIFam | TIGR01537.1 | phage portal protein | NA |
| UHGV-0004425_8 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-0004425_8 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0004425_9 | KOfam | K10421 | CLIP1, RSN; CAP-Gly domain-containing linker protein 1 | NA |
| UHGV-0004425_9 | PHROG | phrog_1533 | tail length tape measure protein | tail |
| UHGV-0004425_9 | eggNOG-mapper | 1235802.C823_01531 | Phage tail tape measure protein, TP901 family | NA |
| UHGV-0004425_9 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0004425_9 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0004425_9 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-0004425_10 | PHROG | phrog_888 | NA | unknown function |
| UHGV-0004425_10 | UniRef90 | UniRef90_B0MKT9 | SHOCT domain-containing protein | NA |
| UHGV-0004425_10 | eggNOG-mapper | 1029718.SFBM_0110 | Short C-terminal domain | NA |
| UHGV-0004425_10 | Pfam | PF09851 | Short C-terminal domain | SHOCT |
| UHGV-0004425_11 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-0004425_11 | UniRef90 | UniRef90_D4JVI5 | Phage terminase-like protein, large subunit | NA |
| UHGV-0004425_11 | eggNOG-mapper | 742738.HMPREF9460_01363 | Phage Terminase | NA |
| UHGV-0004425_11 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-0004425_11 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-0004425_11 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-0004425_11 | Structural annotation | PF20441, PF03354, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0004425_13 | PHROG | phrog_1865 | NA | unknown function |
| UHGV-0004425_13 | Structural annotation | PF07073, MF_01077, NF037951, COG4568 | NA | NA |
| UHGV-0004425_14 | PHROG | phrog_19468 | NA | unknown function |
| UHGV-0004425_14 | UniRef90 | UniRef90_A0A1Q6Q237 | Ntox50 domain-containing protein | NA |
| UHGV-0004425_14 | eggNOG-mapper | 1298920.KI911353_gene4854 | Phage minor capsid protein 2 | NA |
| UHGV-0004425_14 | Pfam | PF15542 | Bacterial toxin 50 | Ntox50 |
| UHGV-0004425_14 | COG | COG2369 | NA | NA |
| UHGV-0004425_15 | Structural annotation | PF11836 | NA | NA |
| UHGV-0004425_16 | PHROG | phrog_88 | major tail protein | tail |
| UHGV-0004425_16 | UniRef90 | UniRef90_A0A3D1SGI5 | Phage tail protein (Fragment) | NA |
| UHGV-0004425_16 | eggNOG-mapper | 1201292.DR75_1505 | Maj_tail_phi13 phage major tail , phi13 family protein | NA |
| UHGV-0004425_16 | NCBIFam | TIGR01603.1 | major tail protein | NA |
| UHGV-0004425_16 | COG | COG5492 | NA | NA |
| UHGV-0004425_16 | Structural annotation | PF04630, TIGR01603, COG3498 | NA | NA |
| UHGV-0004425_17 | Structural annotation | PF17395, TIGR01725 | NA | NA |
| UHGV-0004425_18 | Structural annotation | PF05657 | NA | NA |
| UHGV-0004425_19 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-0004425_20 | PHROG | phrog_40 | head-tail adaptor Ad1 | connector |
| UHGV-0004425_20 | UniRef90 | UniRef90_A0A352DNU5 | Phage gp6-like head-tail connector protein | NA |
| UHGV-0004425_20 | eggNOG-mapper | 1285586.H131_21297 | Phage gp6-like head-tail connector protein | NA |
| UHGV-0004425_20 | Pfam | PF05135 | Phage gp6-like head-tail connector protein | Phage_connect_1 |
| UHGV-0004425_20 | NCBIFam | TIGR01560.2 | head-tail connector protein | NA |
| UHGV-0004425_20 | Structural annotation | PF05135, TIGR01560 | NA | NA |
| UHGV-0004425_22 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0004425_22 | UniRef90 | UniRef90_A0A3D1SDV2 | Phage major capsid protein | NA |
| UHGV-0004425_22 | eggNOG-mapper | 1414720.CBYM010000002_gene572 | Phage major capsid protein, HK97 family | NA |
| UHGV-0004425_22 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0004425_22 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0004425_22 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0004425_22 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0004425_23 | KOfam | K06904 | NA | NA |
| UHGV-0004425_23 | PHROG | phrog_80 | head maturation protease | head and packaging |
| UHGV-0004425_23 | UniRef90 | UniRef90_A0A3D1SFA7 | HK97 family phage prohead protease (Fragment) | NA |
| UHGV-0004425_23 | eggNOG-mapper | 1196031.ALEG01000039_gene1815 | Phage prohead protease, HK97 family | NA |
| UHGV-0004425_23 | Pfam | PF04586 | Caudovirus prohead serine protease | Peptidase_S78 |
| UHGV-0004425_23 | NCBIFam | TIGR01543.1 | HK97 family phage prohead protease | NA |
| UHGV-0004425_23 | COG | COG3740 | Phage head maturation protease | NA |
| UHGV-0004425_23 | Structural annotation | PF04586, TIGR01543, COG3740 | NA | NA |
| UHGV-0004425_25 | PHROG | phrog_83 | terminase small subunit | head and packaging |
| UHGV-0004425_25 | UniRef90 | UniRef90_A0A1C6JNN5 | Phage terminase, small subunit | NA |
| UHGV-0004425_25 | eggNOG-mapper | 1449126.JQKL01000051_gene3175 | NA | NA |
| UHGV-0004425_25 | Structural annotation | PF05119, TIGR01558, COG3747 | NA | NA |
| UHGV-0004425_26 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0004425_26 | UniRef90 | UniRef90_A0A174ZYK6 | Phage transcriptional regulator, RinA family | NA |
| UHGV-0004425_26 | eggNOG-mapper | 1304880.JAGB01000002_gene2225 | NA | NA |
| UHGV-0004425_26 | Structural annotation | PF05263 | NA | NA |
| UHGV-0004425_27 | PHROG | phrog_599 | Lar-like restriction alleviation protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-0004425_27 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-0004425_27 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-0004425_32 | PHROG | phrog_3136 | NA | unknown function |
| UHGV-0004425_32 | UniRef90 | UniRef90_UPI001C26B029 | ASCH domain-containing protein | NA |
| UHGV-0004425_32 | COG | COG4933 | Predicted transcriptional regulator, contains an HTH and PUA-like domains | NA |
| UHGV-0004425_32 | Structural annotation | PF08819, MF_00684, NF008917, COG4933 | NA | NA |
| UHGV-0004425_33 | UniRef90 | UniRef90_A0A844KDL0 | YopX domain-containing protein | NA |
| UHGV-0004425_33 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-0004425_34 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-0004425_34 | UniRef90 | UniRef90_UPI00189B8BA4 | YopX family protein | NA |
| UHGV-0004425_34 | eggNOG-mapper | 457412.RSAG_01162 | YopX protein | NA |
| UHGV-0004425_34 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-0004425_34 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-0004425_35 | KOfam | K01160 | rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10] | NA |
| UHGV-0004425_35 | PHROG | phrog_140 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0004425_35 | UniRef90 | UniRef90_A0A2V2FY53 | RusA family crossover junction endodeoxyribonuclease | NA |
| UHGV-0004425_35 | eggNOG-mapper | 857293.CAAU_0790 | Endodeoxyribonuclease RusA | NA |
| UHGV-0004425_35 | Pfam | PF05866 | Endodeoxyribonuclease RusA | RusA |
| UHGV-0004425_35 | COG | COG4570 | Holliday junction resolvase RusA (prophage-encoded endonuclease) | NA |
| UHGV-0004425_35 | Structural annotation | PF05866, NF007305, COG4570 | NA | NA |
| UHGV-0004425_36 | PHROG | phrog_2562 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0004425_36 | UniRef90 | UniRef90_A0A415UCS3 | NA | NA |
| UHGV-0004425_36 | eggNOG-mapper | 537013.CLOSTMETH_01717 | NA | NA |
| UHGV-0004425_36 | Pfam | PF14297 | Lin1244/Lin1753-like, N-terminal | Lin1244_N |
| UHGV-0004425_36 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-0004425_36 | Structural annotation | PF14297, TIGR01714 | NA | NA |
| UHGV-0004425_37 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0004425_37 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0004425_37 | UniRef90 | UniRef90_R5GS36 | Single-stranded DNA-binding protein | NA |
| UHGV-0004425_37 | eggNOG-mapper | 665956.HMPREF1032_00430 | Single-stranded DNA-binding protein | NA |
| UHGV-0004425_37 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0004425_37 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0004425_37 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0004425_37 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0004425_37 | Structural annotation | PF00436, MF_00984, NF005242, COG0629 | NA | NA |
| UHGV-0004425_38 | KOfam | K06167 | phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55] | NA |
| UHGV-0004425_38 | PHROG | phrog_392 | metal-dependent hydrolase | other |
| UHGV-0004425_38 | UniRef90 | UniRef90_A0A3D1SII0 | MBL fold metallo-hydrolase | NA |
| UHGV-0004425_38 | eggNOG-mapper | 537013.CLOSTMETH_01716 | Metallo-beta-lactamase superfamily | NA |
| UHGV-0004425_38 | Pfam | PF12706 | Beta-lactamase superfamily domain | Lactamase_B_2 |
| UHGV-0004425_38 | dbAPIS | APIS041 | NA | NA |
| UHGV-0004425_38 | COG | COG1235 | Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase | NA |
| UHGV-0004425_38 | Structural annotation | PF02112, MF_01818, NF041851, COG1234 | NA | NA |
| UHGV-0004425_39 | KOfam | K07455 | recT; recombination protein RecT | NA |
| UHGV-0004425_39 | PHROG | phrog_148 | RecT-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0004425_39 | UniRef90 | UniRef90_A0A3D1SF45 | Recombinase | NA |
| UHGV-0004425_39 | eggNOG-mapper | 1118054.CAGW01000106_gene3693 | RecT family | NA |
| UHGV-0004425_39 | Pfam | PF03837 | RecT family | RecT |
| UHGV-0004425_39 | COG | COG3723 | Recombinational DNA repair protein RecT | NA |
| UHGV-0004425_39 | Structural annotation | PF03837, NF007351, COG3723 | NA | NA |
| UHGV-0004425_41 | KOfam | K03546 | sbcC, rad50; DNA repair protein SbcC/Rad50 | NA |
| UHGV-0004425_41 | PHROG | phrog_1499 | NA | unknown function |
| UHGV-0004425_41 | UniRef90 | UniRef90_A0A3D4L3T4 | Chromosome segregation protein SMC | NA |
| UHGV-0004425_41 | eggNOG-mapper | 1262914.BN533_01950 | AAA domain | NA |
| UHGV-0004425_41 | Pfam | PF13476 | AAA domain | AAA_23 |
| UHGV-0004425_41 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0004425_42 | KOfam | K24451 | zim; modification methylase | NA |
| UHGV-0004425_42 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-0004425_42 | UniRef90 | UniRef90_A0A374BT14 | Methyltransferase | NA |
| UHGV-0004425_42 | eggNOG-mapper | 411473.RUMCAL_00273 | Belongs to the N(4) N(6)-methyltransferase family | NA |
| UHGV-0004425_42 | PADLOC | MTase_II_00139 | Type II methyltransferase | RM |
| UHGV-0004425_42 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-0004425_42 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-0004425_42 | Structural annotation | PF01555, MF_01872, NF010253, COG0863 | NA | NA |
| UHGV-0004425_43 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-0004425_43 | PHROG | phrog_16 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0004425_43 | UniRef90 | UniRef90_A0A1I2DWG9 | Superfamily II DNA or RNA helicase | NA |
| UHGV-0004425_43 | eggNOG-mapper | 411473.RUMCAL_00274 | DEAD-like helicases superfamily | NA |
| UHGV-0004425_43 | Pfam | PF04851 | Type III restriction enzyme, res subunit | ResIII |
| UHGV-0004425_43 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-0004425_43 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-0004425_43 | Structural annotation | PF18766, PF16203, MF_01821, TIGR04095, COG0553 | NA | NA |
| UHGV-0004425_47 | UniRef90 | UniRef90_UPI00196A25AB | helix-turn-helix domain-containing protein | NA |
| UHGV-0004425_47 | Pfam | PF12728 | Helix-turn-helix domain | HTH_17 |
| UHGV-0004425_47 | NCBIFam | TIGR01764.1 | excisionase family DNA-binding protein | NA |
| UHGV-0004425_47 | COG | COG0789 | DNA-binding transcriptional regulator, MerR family | NA |
| UHGV-0004425_47 | Structural annotation | PF12728, NF040990, COG3311 | NA | NA |
| UHGV-0004425_48 | UniRef90 | UniRef90_R5L7P6 | Helix-turn-helix | NA |
| UHGV-0004425_48 | eggNOG-mapper | 1410626.JHXB01000005_gene1347 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0004425_48 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0004425_48 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0004425_48 | Structural annotation | PF01381, MF_00535, NF007257, COG1396 | NA | NA |
| UHGV-0004425_49 | Structural annotation | MF_00273, NF001981 | NA | NA |
| UHGV-0004425_50 | UniRef90 | UniRef90_A0A316PY13 | NA | NA |
| UHGV-0004425_50 | eggNOG-mapper | 1121335.Clst_0370 | NA | NA |
| UHGV-0004425_50 | Pfam | PF05339 | NA | DUF739 |
| UHGV-0004425_50 | Structural annotation | PF05339, NF041951, COG3655 | NA | NA |
| UHGV-0004425_51 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-0004425_51 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0004425_51 | UniRef90 | UniRef90_L7VL72 | Putative transcriptional regulator | NA |
| UHGV-0004425_51 | eggNOG-mapper | 1121335.Clst_0369 | helix-turn-helix | NA |
| UHGV-0004425_51 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0004425_51 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0004425_51 | Structural annotation | PF13560, MF_00535, NF007257, COG3655 | NA | NA |
| UHGV-0004425_52 | PHROG | phrog_1914 | NA | unknown function |
| UHGV-0004425_52 | UniRef90 | UniRef90_UPI001D082E60 | ImmA/IrrE family metallo-endopeptidase | NA |
| UHGV-0004425_52 | eggNOG-mapper | 1160721.RBI_I01604 | NA | NA |
| UHGV-0004425_52 | Pfam | PF06114 | IrrE N-terminal-like domain | Peptidase_M78 |
| UHGV-0004425_52 | COG | COG2856 | Zn-dependent peptidase ImmA, M78 family | NA |
| UHGV-0004425_52 | Structural annotation | PF06114, COG2856 | NA | NA |
| UHGV-0004425_53 | KOfam | K02342 | dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] | NA |
| UHGV-0004425_53 | PHROG | phrog_192 | DNA polymerase exonuclease subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0004425_53 | UniRef90 | UniRef90_R5HI47 | DNA polymerase III | NA |
| UHGV-0004425_53 | eggNOG-mapper | 1123288.SOV_2c03960 | DNA polymerase III | NA |
| UHGV-0004425_53 | PADLOC | cd06127 | CAS-I,CAS-II,CAS-III,CAS-IV,CAS-V,CAS-VI; associated | CRISPR-CAS |
| UHGV-0004425_53 | Pfam | PF00929 | Exonuclease | RNase_T |
| UHGV-0004425_53 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-0004425_53 | NCBIFam | TIGR00573.1 | exonuclease, DNA polymerase III, epsilon subunit family | NA |
| UHGV-0004425_53 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0004425_53 | Structural annotation | PF00929, PF00533, MF_00157, NF005289, COG0847 | NA | NA |
| UHGV-0004425_54 | eggNOG-mapper | 1232453.BAIF02000097_gene2773 | EXOIII | NA |
| UHGV-0004425_54 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0004425_55 | KOfam | K14059 | int; integrase | NA |
| UHGV-0004425_55 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0004425_55 | UniRef90 | UniRef90_B0ML01 | Site-specific recombinase, phage integrase family | NA |
| UHGV-0004425_55 | eggNOG-mapper | 428125.CLOLEP_02743 | Belongs to the 'phage' integrase family | NA |
| UHGV-0004425_55 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-0004425_55 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0004425_55 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-0004425_55 | Structural annotation | PF00589, PF14659, MF_02055, TIGR02224, COG4974 | NA | NA |