| UHGV-0384105_1 | UniRef90 | UniRef90_A0A412L6E4 | Cas9_PI domain-containing protein | NA |
| UHGV-0384105_1 | eggNOG-mapper | 471875.RUMLAC_00178 | CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer | NA |
| UHGV-0384105_1 | PADLOC | mkCas0193 | CAS-II-A,CAS-II-B,CAS-II-C; effector__SPE | CRISPR-CAS |
| UHGV-0384105_1 | Pfam | PF16595 | PAM-interacting domain of CRISPR-associated endonuclease Cas9 | Cas9_PI |
| UHGV-0384105_1 | COG | COG3513 | CRISPR-Cas system type-II protein Cas9 | NA |
| UHGV-0384105_2 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-0384105_2 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0384105_2 | UniRef90 | UniRef90_A0A1C6GZH6 | LexA repressor | NA |
| UHGV-0384105_2 | eggNOG-mapper | 1160721.RBI_II00559 | Peptidase S24-like | NA |
| UHGV-0384105_2 | Pfam | PF12844 | Helix-turn-helix domain | HTH_19 |
| UHGV-0384105_2 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-0384105_2 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0384105_2 | Structural annotation | PF00717, PF12844, MF_00015, NF007621, NF041951, COG2932 | NA | NA |
| UHGV-0384105_3 | KOfam | K23779 | sutR; XRE family transcriptional regulator, regulator of sulfur utilization | NA |
| UHGV-0384105_3 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0384105_3 | UniRef90 | UniRef90_A0A1C6GZN2 | Anaerobic benzoate catabolism transcriptional regulator | NA |
| UHGV-0384105_3 | eggNOG-mapper | 431943.CKL_1947 | sequence-specific DNA binding | NA |
| UHGV-0384105_3 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0384105_3 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0384105_3 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-0384105_6 | PHROG | phrog_310 | transposase | integration and excision |
| UHGV-0384105_6 | UniRef90 | UniRef90_A0A413QHZ6 | MerR family transcriptional regulator | NA |
| UHGV-0384105_6 | eggNOG-mapper | 445972.ANACOL_00518 | Mu transposase, C-terminal | NA |
| UHGV-0384105_6 | PADLOC | TnsB_0_V-K | TnsB_0_V-K | CRISPR-CAS |
| UHGV-0384105_6 | Pfam | PF09039 | Mu DNA binding, I gamma subdomain | HTH_Tnp_Mu_2 |
| UHGV-0384105_6 | Pfam | PF09299 | Mu transposase, C-terminal | Mu-transpos_C |
| UHGV-0384105_6 | COG | COG2801 | Transposase InsO and inactivated derivatives | NA |
| UHGV-0384105_6 | Structural annotation | PF02914, PF09039, PF09299, PF21531, NF033594, TIGR01764, COG3316, COG3311 | NA | NA |
| UHGV-0384105_7 | KOfam | K07132 | MuB; ATP-dependent target DNA activator | NA |
| UHGV-0384105_7 | PHROG | phrog_296 | DNA transposition protein | integration and excision |
| UHGV-0384105_7 | UniRef90 | UniRef90_A0A413QHD1 | AAA domain-containing protein | NA |
| UHGV-0384105_7 | eggNOG-mapper | 1160721.RBI_II00554 | AAA domain | NA |
| UHGV-0384105_7 | Pfam | PF13401 | AAA domain | AAA_22 |
| UHGV-0384105_7 | COG | COG2842 | Bacteriophage DNA transposition protein, AAA+ family ATPase | NA |
| UHGV-0384105_7 | Structural annotation | PF13401, MF_01407, TIGR03015, COG2842 | NA | NA |
| UHGV-0384105_9 | PHROG | phrog_5671 | NA | unknown function |
| UHGV-0384105_9 | eggNOG-mapper | 552398.HMPREF0866_03130 | NA | NA |
| UHGV-0384105_11 | KOfam | K06284 | abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes | NA |
| UHGV-0384105_11 | PHROG | phrog_4681 | antitoxin from a toxin-antitoxin system | moron, auxiliary metabolic gene and host takeover |
| UHGV-0384105_11 | UniRef90 | UniRef90_A0A413QH66 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | NA |
| UHGV-0384105_11 | eggNOG-mapper | 742733.HMPREF9469_02890 | toxin-antitoxin pair type II binding | NA |
| UHGV-0384105_11 | NCBIFam | TIGR01439.1 | transcriptional regulator, AbrB family | NA |
| UHGV-0384105_11 | COG | COG2002 | Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module | NA |
| UHGV-0384105_11 | Structural annotation | PF15937, TIGR01439, NF004424, COG2002 | NA | NA |
| UHGV-0384105_12 | eggNOG-mapper | 645991.Sgly_0760 | NA | NA |
| UHGV-0384105_13 | PHROG | phrog_286 | NA | unknown function |
| UHGV-0384105_13 | UniRef90 | UniRef90_A0A373KYV3 | NA | NA |
| UHGV-0384105_13 | eggNOG-mapper | 445972.ANACOL_00525 | NA | NA |
| UHGV-0384105_13 | Pfam | PF06252 | Bacteriophage Mu, GemA protein | GemA |
| UHGV-0384105_13 | Structural annotation | PF06252 | NA | NA |
| UHGV-0384105_14 | PHROG | phrog_532 | late transcriptional activator | transcription regulation |
| UHGV-0384105_14 | UniRef90 | UniRef90_A0A373L0N7 | Mor domain-containing protein | NA |
| UHGV-0384105_14 | eggNOG-mapper | 411483.FAEPRAA2165_03398 | Mor transcription activator family | NA |
| UHGV-0384105_14 | Pfam | PF08765 | Mor transcription activator family | Mor |
| UHGV-0384105_14 | COG | COG5566 | Transcriptional regulator, middle operon regulator (Mor) family | NA |
| UHGV-0384105_14 | Structural annotation | PF08765, NF040785, COG5566 | NA | NA |
| UHGV-0384105_15 | eggNOG-mapper | 663278.Ethha_0085 | NA | NA |
| UHGV-0384105_16 | PHROG | phrog_25462 | NA | unknown function |
| UHGV-0384105_16 | UniRef90 | UniRef90_A0A413QHC4 | Type VI secretion protein | NA |
| UHGV-0384105_16 | eggNOG-mapper | 1160721.RBI_II00547 | NA | NA |
| UHGV-0384105_16 | Structural annotation | PF01638, MF_01819, NF002926, COG1733 | NA | NA |
| UHGV-0384105_17 | PHROG | phrog_426 | terminase small subunit | head and packaging |
| UHGV-0384105_17 | UniRef90 | UniRef90_A0A373L007 | NA | NA |
| UHGV-0384105_17 | eggNOG-mapper | 411902.CLOBOL_06314 | NA | NA |
| UHGV-0384105_17 | Pfam | PF11985 | Bacteriophage Mu, Gp27 | Phage_Mu_Gp27 |
| UHGV-0384105_17 | Structural annotation | PF11985 | NA | NA |
| UHGV-0384105_18 | KOfam | K02601 | nusG; transcription termination/antitermination protein NusG | NA |
| UHGV-0384105_18 | PHROG | phrog_6386 | transcription antiterminator | transcription regulation |
| UHGV-0384105_18 | UniRef90 | UniRef90_A0A413QHD3 | NGN domain-containing protein | NA |
| UHGV-0384105_18 | eggNOG-mapper | 1123489.AUAN01000019_gene1519 | Participates in transcription elongation, termination and antitermination | NA |
| UHGV-0384105_18 | Pfam | PF02357 | Transcription termination factor nusG | NusG |
| UHGV-0384105_18 | COG | COG0250 | Transcription termination/antitermination protein NusG | NA |
| UHGV-0384105_18 | Structural annotation | PF02357, MF_00951, NF033641, COG0250 | NA | NA |
| UHGV-0384105_20 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0384105_20 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-0384105_20 | UniRef90 | UniRef90_A0A373L0G3 | PBSX family phage terminase large subunit | NA |
| UHGV-0384105_20 | eggNOG-mapper | 693746.OBV_18030 | Phage terminase large subunit | NA |
| UHGV-0384105_20 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-0384105_20 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-0384105_20 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0384105_20 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0384105_21 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-0384105_21 | UniRef90 | UniRef90_A0A3D0XCF1 | Phage capsid protein | NA |
| UHGV-0384105_21 | eggNOG-mapper | 411490.ANACAC_00782 | NA | NA |
| UHGV-0384105_21 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-0384105_22 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-0384105_22 | UniRef90 | UniRef90_A0A1C6IA10 | Phage minor capsid protein 2 | NA |
| UHGV-0384105_22 | eggNOG-mapper | 663278.Ethha_0091 | NA | NA |
| UHGV-0384105_22 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-0384105_22 | COG | COG2369 | NA | NA |
| UHGV-0384105_22 | Structural annotation | PF06152, PF12636 | NA | NA |
| UHGV-0384105_24 | PHROG | phrog_194 | head scaffolding protein | head and packaging |
| UHGV-0384105_24 | UniRef90 | UniRef90_UPI001967FAB3 | phage scaffolding protein | NA |
| UHGV-0384105_24 | eggNOG-mapper | 1401067.HMPREF0872_00300 | Phage minor structural protein GP20 | NA |
| UHGV-0384105_24 | Pfam | PF06810 | Phage minor structural protein GP20 | Phage_GP20 |
| UHGV-0384105_24 | Structural annotation | PF06810 | NA | NA |
| UHGV-0384105_25 | PHROG | phrog_212 | major head protein | head and packaging |
| UHGV-0384105_25 | UniRef90 | UniRef90_A0A373KYA5 | Phage capsid protein | NA |
| UHGV-0384105_25 | eggNOG-mapper | 935836.JAEL01000021_gene1494 | NA | NA |
| UHGV-0384105_25 | Structural annotation | PF05065, MF_04119, NF041162, COG4653 | NA | NA |
| UHGV-0384105_26 | PHROG | phrog_541 | head-tail adaptor | connector |
| UHGV-0384105_26 | eggNOG-mapper | 1120998.AUFC01000030_gene2237 | NA | NA |
| UHGV-0384105_27 | PHROG | phrog_3366 | NA | unknown function |
| UHGV-0384105_27 | eggNOG-mapper | 1151292.QEW_4533 | NA | NA |
| UHGV-0384105_27 | Pfam | PF20536 | NA | DUF6751 |
| UHGV-0384105_28 | PHROG | phrog_556 | minor head protein | head and packaging |
| UHGV-0384105_28 | UniRef90 | UniRef90_A0A413QH49 | Capsid protein | NA |
| UHGV-0384105_28 | eggNOG-mapper | 883114.HMPREF9709_01190 | Minor capsid protein | NA |
| UHGV-0384105_28 | Pfam | PF11114 | Minor capsid protein | Minor_capsid_2 |
| UHGV-0384105_28 | Structural annotation | PF11114 | NA | NA |
| UHGV-0384105_29 | PHROG | phrog_3266 | tail completion | connector |
| UHGV-0384105_29 | UniRef90 | UniRef90_A0A373KYC6 | Chloramphenicol resistance protein | NA |
| UHGV-0384105_29 | eggNOG-mapper | 641112.ACOK01000073_gene2899 | NA | NA |
| UHGV-0384105_29 | Structural annotation | PF12691 | NA | NA |
| UHGV-0384105_30 | PHROG | phrog_3099 | NA | unknown function |
| UHGV-0384105_30 | UniRef90 | UniRef90_A0A3P6KYP0 | Phage capsid family protein | NA |
| UHGV-0384105_30 | eggNOG-mapper | 411490.ANACAC_00772 | NA | NA |
| UHGV-0384105_30 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-0384105_31 | PHROG | phrog_4450 | NA | unknown function |
| UHGV-0384105_31 | UniRef90 | UniRef90_A0A413QHF8 | AP endonuclease | NA |
| UHGV-0384105_31 | eggNOG-mapper | 1280692.AUJL01000004_gene838 | NA | NA |
| UHGV-0384105_31 | Pfam | PF20378 | NA | DUF6673 |
| UHGV-0384105_31 | Structural annotation | PF20378 | NA | NA |
| UHGV-0384105_32 | PHROG | phrog_706 | NA | unknown function |
| UHGV-0384105_32 | UniRef90 | UniRef90_A0A1G4WU45 | Bacteriophage Gp15 protein | NA |
| UHGV-0384105_32 | eggNOG-mapper | 1499683.CCFF01000017_gene2567 | Bacteriophage Gp15 protein | NA |
| UHGV-0384105_32 | Pfam | PF06854 | Bacteriophage Gp15 protein | Phage_Gp15 |
| UHGV-0384105_32 | Structural annotation | PF06854 | NA | NA |
| UHGV-0384105_33 | PHROG | phrog_37750 | NA | unknown function |
| UHGV-0384105_33 | UniRef90 | UniRef90_A0A1G4WVI6 | Beta-lactamase inhibitor (BLIP) | NA |
| UHGV-0384105_33 | eggNOG-mapper | 1280390.CBQR020000086_gene1875 | NA | NA |
| UHGV-0384105_34 | PHROG | phrog_19074 | NA | unknown function |
| UHGV-0384105_34 | UniRef90 | UniRef90_A0A373L0L9 | Phage tail tape measure protein | NA |
| UHGV-0384105_34 | eggNOG-mapper | 33035.JPJF01000033_gene2265 | Phage-related minor tail protein | NA |
| UHGV-0384105_34 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0384105_34 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0384105_34 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-0384105_34 | Structural annotation | PF10145, TIGR01760, COG5280 | NA | NA |
| UHGV-0384105_35 | UniRef90 | UniRef90_A0A1G4WVH7 | Phage-related protein | NA |
| UHGV-0384105_35 | eggNOG-mapper | 1347392.CCEZ01000045_gene7 | phage tail | NA |
| UHGV-0384105_35 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0384105_35 | Structural annotation | PF20753, PF20195, TIGR01633, COG4722 | NA | NA |
| UHGV-0384105_36 | PHROG | phrog_18110 | NA | unknown function |
| UHGV-0384105_36 | UniRef90 | UniRef90_A0A373KYA3 | Prophage_tail domain-containing protein | NA |
| UHGV-0384105_36 | eggNOG-mapper | 1280689.AUJC01000007_gene3306 | Phage minor structural protein | NA |
| UHGV-0384105_36 | Pfam | PF06605 | Prophage endopeptidase tail | Prophage_tail |
| UHGV-0384105_36 | NCBIFam | TIGR01665.1 | phage tail spike protein | NA |
| UHGV-0384105_36 | COG | COG4733 | Phage-related protein, tail protein J | NA |
| UHGV-0384105_36 | Structural annotation | PF06605, PF18994, TIGR01665, COG4926 | NA | NA |
| UHGV-0384105_38 | PHROG | phrog_11105 | NA | unknown function |
| UHGV-0384105_39 | UniRef90 | UniRef90_A0A1C6HHE5 | BppU_N domain-containing protein | NA |
| UHGV-0384105_39 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-0384105_39 | Structural annotation | PF10651, PF08931, TIGR02268 | NA | NA |
| UHGV-0384105_41 | eggNOG-mapper | 642492.Clole_0840 | NA | NA |
| UHGV-0384105_41 | Pfam | PF04531 | Bacteriophage holin | Phage_holin_1 |
| UHGV-0384105_42 | PHROG | phrog_21357 | endolysin | lysis |
| UHGV-0384105_42 | UniRef90 | UniRef90_A0A373L0D7 | CHAP domain-containing protein | NA |
| UHGV-0384105_42 | eggNOG-mapper | 693746.OBV_19030 | CHAP domain | NA |
| UHGV-0384105_42 | Pfam | PF05257 | CHAP domain | CHAP |
| UHGV-0384105_42 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0384105_42 | COG | COG0791 | Cell wall-associated hydrolase, NlpC_P60 family | NA |
| UHGV-0384105_42 | Structural annotation | PF01471, PF00877, TIGR02594, TIGR03979, COG3942 | NA | NA |
| UHGV-0384105_43 | KOfam | K06223 | dam; DNA adenine methylase [EC:2.1.1.72] | NA |
| UHGV-0384105_43 | PHROG | phrog_56 | DNA methyltransferase | other |
| UHGV-0384105_43 | UniRef90 | UniRef90_A0A1C6HHY1 | Site-specific DNA-methyltransferase (adenine-specific) | NA |
| UHGV-0384105_43 | eggNOG-mapper | 411902.CLOBOL_03426 | COG COG0338 Site-specific DNA methylase | NA |
| UHGV-0384105_43 | PADLOC | MTase_II_00080 | Type II methyltransferase | RM |
| UHGV-0384105_43 | Pfam | PF02086 | D12 class N6 adenine-specific DNA methyltransferase | MethyltransfD12 |
| UHGV-0384105_43 | NCBIFam | TIGR00571.1 | Dam family site-specific DNA-(adenine-N6)-methyltransferase | NA |
| UHGV-0384105_43 | COG | COG0338 | DNA-adenine methylase | NA |
| UHGV-0384105_43 | Structural annotation | PF02086, MF_01872, NF008152, COG0338 | NA | NA |
| UHGV-0384105_44 | KOfam | K07727 | K07727; putative transcriptional regulator | NA |
| UHGV-0384105_44 | UniRef90 | UniRef90_A0A373KZS3 | XRE family transcriptional regulator | NA |
| UHGV-0384105_44 | eggNOG-mapper | 411471.SUBVAR_06679 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-0384105_44 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0384105_44 | COG | COG3655 | DNA-binding transcriptional regulator, XRE family | NA |
| UHGV-0384105_45 | KOfam | K09952 | csn1, cas9; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-] | NA |
| UHGV-0384105_45 | UniRef90 | UniRef90_A0A374N1Y3 | CRISPR-associated endonuclease Cas9 | NA |
| UHGV-0384105_45 | eggNOG-mapper | 411462.DORLON_02599 | CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer | NA |
| UHGV-0384105_45 | PADLOC | mkCas0193 | CAS-II-A,CAS-II-B,CAS-II-C; effector__SPE | CRISPR-CAS |
| UHGV-0384105_45 | Pfam | PF16593 | Bridge helix of CRISPR-associated endonuclease Cas9 | Cas9-BH |
| UHGV-0384105_45 | Pfam | PF16592 | REC lobe of CRISPR-associated endonuclease Cas9 | Cas9_REC |
| UHGV-0384105_45 | Pfam | PF13395 | HNH endonuclease | HNH_4 |
| UHGV-0384105_45 | NCBIFam | TIGR01865.1 | type II CRISPR RNA-guided endonuclease Cas9 | NA |
| UHGV-0384105_45 | COG | COG3513 | CRISPR-Cas system type-II protein Cas9 | NA |
| UHGV-0384105_46 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-0384105_46 | eggNOG-mapper | 641112.ACOK01000073_gene2890 | NA | NA |
| UHGV-0384105_46 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-0384105_46 | COG | COG2369 | NA | NA |