| UHGV-1402599_5 | Pfam | PF20459 | NA | DUF6712 |
| UHGV-1402599_5 | Structural annotation | PF20459 | NA | NA |
| UHGV-1402599_6 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1402599_6 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-1402599_6 | UniRef90 | UniRef90_A0A255TPS1 | Methyltransferase | NA |
| UHGV-1402599_6 | eggNOG-mapper | 483215.BACFIN_05771 | Belongs to the N(4) N(6)-methyltransferase family | NA |
| UHGV-1402599_6 | PADLOC | MTase_II_00037 | Type II methyltransferase | RM |
| UHGV-1402599_6 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1402599_6 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1402599_6 | Structural annotation | PF01555, MF_01872, NF008572, COG0863 | NA | NA |
| UHGV-1402599_7 | eggNOG-mapper | 1235803.C825_03414 | NA | NA |
| UHGV-1402599_7 | Structural annotation | PF05136, MF_04135, TIGR01540, COG5518 | NA | NA |
| UHGV-1402599_8 | Structural annotation | PF13619 | NA | NA |
| UHGV-1402599_9 | PHROG | phrog_2087 | NA | unknown function |
| UHGV-1402599_9 | eggNOG-mapper | 1410653.JHVC01000005_gene2495 | NA | NA |
| UHGV-1402599_10 | PHROG | phrog_1383 | virion structural protein | head and packaging |
| UHGV-1402599_10 | UniRef90 | UniRef90_R6U473 | Gp142 | NA |
| UHGV-1402599_10 | eggNOG-mapper | 1327935.A0A060AD14_9CAUD | NA | NA |
| UHGV-1402599_10 | Structural annotation | COG1704 | NA | NA |
| UHGV-1402599_11 | UniRef90 | UniRef90_A0A6I1S5I8 | GNAT family N-acetyltransferase | NA |
| UHGV-1402599_11 | Pfam | PF00583 | Acetyltransferase (GNAT) family | Acetyltransf_1 |
| UHGV-1402599_11 | COG | COG1670 | Protein N-acetyltransferase, RimJ/RimL family | NA |
| UHGV-1402599_14 | Structural annotation | COG5475 | NA | NA |
| UHGV-1402599_21 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1402599_21 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1402599_21 | UniRef90 | UniRef90_A0A353E5E4 | Cytosine-specific methyltransferase | NA |
| UHGV-1402599_21 | eggNOG-mapper | 1033733.CAEK01000007_gene1648 | Cytosine-specific methyltransferase | NA |
| UHGV-1402599_21 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-1402599_21 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1402599_21 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1402599_21 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1402599_21 | Structural annotation | PF00145, MF_02237, TIGR00675, COG0270 | NA | NA |
| UHGV-1402599_26 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-1402599_26 | UniRef90 | UniRef90_UPI001F45D98B | YopX family protein | NA |
| UHGV-1402599_26 | eggNOG-mapper | 40522.A8ASP1_BPA50 | YopX protein | NA |
| UHGV-1402599_26 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-1402599_26 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-1402599_28 | KOfam | K14415 | RTCB, rtcB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] | NA |
| UHGV-1402599_28 | PHROG | phrog_1075 | tRNA splicing ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1402599_28 | UniRef90 | UniRef90_A0A413CCX6 | RNA-splicing ligase RtcB | NA |
| UHGV-1402599_28 | eggNOG-mapper | 1089548.KI783301_gene2001 | tRNA-splicing ligase RtcB | NA |
| UHGV-1402599_28 | Pfam | PF01139 | tRNA-splicing ligase RtcB | RtcB |
| UHGV-1402599_28 | COG | COG1690 | RNA-splicing ligase RtcB, repairs tRNA damage | NA |
| UHGV-1402599_28 | Structural annotation | PF01139, MF_03144, NF007153, COG1690 | NA | NA |
| UHGV-1402599_29 | Structural annotation | PF10827 | NA | NA |
| UHGV-1402599_30 | PHROG | phrog_874 | NA | unknown function |
| UHGV-1402599_30 | eggNOG-mapper | 762968.HMPREF9441_00541 | NA | NA |
| UHGV-1402599_30 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-1402599_34 | Structural annotation | PF10628 | NA | NA |
| UHGV-1402599_37 | KOfam | K11921 | cynR; LysR family transcriptional regulator, cyn operon transcriptional activator | NA |
| UHGV-1402599_37 | PHROG | phrog_3736 | NA | unknown function |
| UHGV-1402599_37 | UniRef90 | UniRef90_A0A353E8E6 | HTH lysR-type domain-containing protein | NA |
| UHGV-1402599_37 | eggNOG-mapper | 1121890.AUDO01000009_gene38 | Transcriptional regulator | NA |
| UHGV-1402599_37 | Pfam | PF00126 | Bacterial regulatory helix-turn-helix protein, lysR family | HTH_1 |
| UHGV-1402599_37 | Pfam | PF03466 | LysR substrate binding domain | LysR_substrate |
| UHGV-1402599_37 | COG | COG0583 | DNA-binding transcriptional regulator, LysR family | NA |
| UHGV-1402599_37 | Structural annotation | PF03466, PF00126, MF_01233, NF040786, COG0583 | NA | NA |
| UHGV-1402599_38 | Structural annotation | TIGR01603, COG5437 | NA | NA |
| UHGV-1402599_39 | Structural annotation | PF05065, PF18998, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1402599_40 | KOfam | K21511 | GPC; capsid assembly protease [EC:3.4.21.-] | NA |
| UHGV-1402599_40 | PHROG | phrog_53 | head maturation protease | head and packaging |
| UHGV-1402599_40 | UniRef90 | UniRef90_A0A2L2WN07 | Signal peptide peptidase SppA, 36K type | NA |
| UHGV-1402599_40 | eggNOG-mapper | 1236504.HMPREF2132_01855 | serine-type peptidase activity | NA |
| UHGV-1402599_40 | Pfam | PF01343 | Peptidase family S49 | Peptidase_S49 |
| UHGV-1402599_40 | COG | COG0616 | Periplasmic serine protease, ClpP class | NA |
| UHGV-1402599_40 | Structural annotation | PF01343, MF_00444, TIGR00706, COG0616 | NA | NA |
| UHGV-1402599_41 | Structural annotation | PF11550, COG5437 | NA | NA |
| UHGV-1402599_44 | eggNOG-mapper | 1236504.HMPREF2132_01780 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-1402599_44 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-1402599_45 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-1402599_45 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-1402599_45 | UniRef90 | UniRef90_A0A646QQD1 | Putative flavin-dependent thymidylate synthase | NA |
| UHGV-1402599_45 | eggNOG-mapper | 1236504.HMPREF2132_01775 | thymidylate synthase (FAD) activity | NA |
| UHGV-1402599_45 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-1402599_45 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-1402599_45 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-1402599_46 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-1402599_46 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-1402599_46 | UniRef90 | UniRef90_A0A354WXC5 | Guanylate kinase | NA |
| UHGV-1402599_46 | eggNOG-mapper | 1433126.BN938_1741 | Guanylate kinase | NA |
| UHGV-1402599_46 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-1402599_46 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-1402599_46 | Structural annotation | PF00625, MF_00328, TIGR03263, COG0194 | NA | NA |
| UHGV-1402599_48 | UniRef90 | UniRef90_A0A2L2WND9 | Primase C terminal 2 | NA |
| UHGV-1402599_48 | eggNOG-mapper | 1236504.HMPREF2132_01765 | Primase C terminal 2 (PriCT-2) | NA |
| UHGV-1402599_48 | PADLOC | drt-cluster64 | DRT | DRT |
| UHGV-1402599_48 | Pfam | PF08800 | BT4734-like, N-terminal domain | BT4734-like_N |
| UHGV-1402599_48 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-1402599_48 | Structural annotation | PF08800, NF040562 | NA | NA |
| UHGV-1402599_49 | PHROG | phrog_25337 | tail length tape measure protein | tail |
| UHGV-1402599_49 | UniRef90 | UniRef90_A0A2L2WS53 | PhageMin_Tail domain-containing protein | NA |
| UHGV-1402599_49 | eggNOG-mapper | 1236504.HMPREF2132_01670 | tail tape measure protein, TP901 family | NA |
| UHGV-1402599_49 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-1402599_49 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1402599_49 | Structural annotation | PF10145, TIGR01760, COG5280 | NA | NA |
| UHGV-1402599_51 | Structural annotation | PF20765 | NA | NA |
| UHGV-1402599_52 | UniRef90 | UniRef90_UPI001C2BD57F | phage holin family protein | NA |
| UHGV-1402599_52 | eggNOG-mapper | 457424.BFAG_02443 | NA | NA |
| UHGV-1402599_52 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-1402599_52 | Structural annotation | TIGR01593 | NA | NA |
| UHGV-1402599_53 | Pfam | PF05821 | NA | NDUF_B8 |
| UHGV-1402599_54 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-1402599_54 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1402599_54 | UniRef90 | UniRef90_UPI001C38E333 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-1402599_54 | eggNOG-mapper | 357276.EL88_11445 | Phosphoadenosine phosphosulfate reductase family | NA |
| UHGV-1402599_54 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-1402599_54 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-1402599_54 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1402599_54 | Structural annotation | PF01507, MF_00064, NF006327, COG0175 | NA | NA |
| UHGV-1402599_56 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-1402599_56 | UniRef90 | UniRef90_A0A096AV30 | Conjugal transfer protein | NA |
| UHGV-1402599_56 | eggNOG-mapper | 1236504.HMPREF2132_11055 | DNA restriction-modification system | NA |
| UHGV-1402599_56 | COG | COG0827 | Adenine-specific DNA N6-methylase | NA |
| UHGV-1402599_56 | Structural annotation | PF02384, MF_01872, NF012220, COG0286 | NA | NA |
| UHGV-1402599_57 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1402599_57 | PHROG | phrog_67 | DNA methyltransferase | other |
| UHGV-1402599_57 | UniRef90 | UniRef90_A0A2X2SZL0 | Methyltransferase | NA |
| UHGV-1402599_57 | eggNOG-mapper | 1414739.W6ASX7_9CAUD | helicase activity | NA |
| UHGV-1402599_57 | PADLOC | MTase_II_00157 | Type II methyltransferase | RM |
| UHGV-1402599_57 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1402599_57 | Structural annotation | PF01555, MF_01872, NF010253, COG0863 | NA | NA |
| UHGV-1402599_59 | eggNOG-mapper | 1002367.HMPREF0673_02207 | NA | NA |
| UHGV-1402599_59 | Structural annotation | PF04466, PF20441, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1402599_63 | Structural annotation | COG2157 | NA | NA |
| UHGV-1402599_65 | Structural annotation | PF08863 | NA | NA |
| UHGV-1402599_67 | KOfam | K02338 | dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] | NA |
| UHGV-1402599_67 | PHROG | phrog_947 | DNA polymerase processivity factor | DNA, RNA and nucleotide metabolism |
| UHGV-1402599_67 | UniRef90 | UniRef90_A0A2E2XYC7 | Beta sliding clamp | NA |
| UHGV-1402599_67 | eggNOG-mapper | 693979.Bache_1888 | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | NA |
| UHGV-1402599_67 | Pfam | PF00712 | DNA polymerase III beta subunit, N-terminal domain | DNA_pol3_beta |
| UHGV-1402599_67 | Pfam | PF02767 | DNA polymerase III beta subunit, central domain | DNA_pol3_beta_2 |
| UHGV-1402599_67 | Pfam | PF02768 | DNA polymerase III beta subunit, C-terminal domain | DNA_pol3_beta_3 |
| UHGV-1402599_67 | COG | COG0592 | DNA polymerase III sliding clamp (beta) subunit, PCNA homolog | NA |
| UHGV-1402599_67 | Structural annotation | PF02768, PF00712, PF02767, MF_00317, TIGR00663, COG0592 | NA | NA |
| UHGV-1402599_69 | PHROG | phrog_874 | NA | unknown function |
| UHGV-1402599_69 | eggNOG-mapper | 762968.HMPREF9441_00541 | NA | NA |
| UHGV-1402599_69 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-1402599_71 | PHROG | phrog_35807 | NA | unknown function |
| UHGV-1402599_71 | UniRef90 | UniRef90_UPI001EDF0ED9 | RNA polymerase subunit sigma | NA |
| UHGV-1402599_71 | eggNOG-mapper | 357276.EL88_12625 | RNA polymerase activity | NA |
| UHGV-1402599_71 | COG | COG0085 | DNA-directed RNA polymerase, beta subunit/140 kD subunit | NA |
| UHGV-1402599_71 | Structural annotation | PF14902 | NA | NA |
| UHGV-1402599_72 | UniRef90 | UniRef90_A0A096AGU9 | FHA domain-containing protein | NA |
| UHGV-1402599_72 | eggNOG-mapper | 1236504.HMPREF2132_01700 | DNA primase activity | NA |
| UHGV-1402599_72 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-1402599_72 | Structural annotation | PF05272, PF01807, MF_00974, MF_00016, NF005477, COG3378, COG0358 | NA | NA |
| UHGV-1402599_75 | PHROG | phrog_255 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1402599_75 | UniRef90 | UniRef90_A0A355U3Z6 | NA | NA |
| UHGV-1402599_75 | eggNOG-mapper | 1236504.HMPREF2132_01690 | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease | NA |
| UHGV-1402599_75 | Pfam | PF16473 | 3'-5' exoribonuclease Rv2179c-like domain | Rv2179c-like |
| UHGV-1402599_75 | COG | COG0847 | DNA polymerase III, epsilon subunit or related 3'-5' exonuclease | NA |
| UHGV-1402599_75 | Structural annotation | PF16473, MF_00157, TIGR01298, COG5018 | NA | NA |
| UHGV-1402599_77 | Structural annotation | COG3655 | NA | NA |
| UHGV-1402599_78 | Structural annotation | PF17457 | NA | NA |
| UHGV-1402599_81 | UniRef90 | UniRef90_R6XMM2 | Putative initiator RepB protein | NA |
| UHGV-1402599_81 | eggNOG-mapper | 1236504.HMPREF2132_12945 | Initiator RepB protein | NA |
| UHGV-1402599_81 | Pfam | PF21205 | Initiator Rep protein, WH2 | Rep3_C |
| UHGV-1402599_81 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-1402599_81 | Structural annotation | PF20964, PF07112, NF010305, COG5527 | NA | NA |
| UHGV-1402599_82 | Structural annotation | PF07878, COG3905 | NA | NA |
| UHGV-1402599_83 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-1402599_83 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-1402599_83 | UniRef90 | UniRef90_A0A095Z6L5 | AAA_31 domain-containing protein | NA |
| UHGV-1402599_83 | eggNOG-mapper | 1236504.HMPREF2132_02105 | CobQ CobB MinD ParA nucleotide binding domain | NA |
| UHGV-1402599_83 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-1402599_83 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-1402599_83 | Structural annotation | PF13614, MF_00533, NF041283, COG1192 | NA | NA |
| UHGV-1402599_84 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-1402599_84 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-1402599_84 | UniRef90 | UniRef90_A0A2L2WS96 | DNA ligase (NAD(+)) | NA |
| UHGV-1402599_84 | eggNOG-mapper | 1123248.KB893386_gene1852 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-1402599_84 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-1402599_84 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-1402599_84 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-1402599_84 | Structural annotation | PF01653, PF03120, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-1402599_87 | KOfam | K23779 | sutR; XRE family transcriptional regulator, regulator of sulfur utilization | NA |
| UHGV-1402599_87 | PHROG | phrog_5823 | transcriptional regulator | transcription regulation |
| UHGV-1402599_87 | UniRef90 | UniRef90_A0A419S8Y6 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1402599_87 | eggNOG-mapper | 679937.Bcop_2150 | Helix-turn-helix domain | NA |
| UHGV-1402599_87 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1402599_87 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1402599_87 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1402599_87 | Structural annotation | PF13560, TIGR03070, COG1396 | NA | NA |
| UHGV-1402599_93 | Structural annotation | PF14528, NF007435 | NA | NA |
| UHGV-1402599_94 | KOfam | K03427 | hsdM; type I restriction enzyme M protein [EC:2.1.1.72] | NA |
| UHGV-1402599_94 | PHROG | phrog_5696 | NA | unknown function |
| UHGV-1402599_94 | UniRef90 | UniRef90_A0A6L5XAE6 | N-6 DNA methylase | NA |
| UHGV-1402599_94 | eggNOG-mapper | 552811.Dehly_0230 | HsdM N-terminal domain | NA |
| UHGV-1402599_94 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-1402599_94 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-1402599_94 | Structural annotation | COG0286 | NA | NA |