| UHGV-2045668_2 | PHROG | phrog_18444 | NA | unknown function |
| UHGV-2045668_3 | PHROG | phrog_6616 | tail protein | tail |
| UHGV-2045668_3 | UniRef90 | UniRef90_UPI0015714EA8 | tail fiber domain-containing protein | NA |
| UHGV-2045668_3 | eggNOG-mapper | 357276.EL88_12830 | Phage minor structural protein | NA |
| UHGV-2045668_3 | COG | COG4926 | Phage-related protein | NA |
| UHGV-2045668_3 | Structural annotation | PF05113, PF01835, PF03921, NF033848, COG3500 | NA | NA |
| UHGV-2045668_4 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-2045668_4 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-2045668_5 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-2045668_5 | UniRef90 | UniRef90_A0A173R880 | Phage-related protein | NA |
| UHGV-2045668_5 | eggNOG-mapper | 476272.RUMHYD_01785 | phage tail tape measure protein | NA |
| UHGV-2045668_5 | COG | COG1511 | NA | NA |
| UHGV-2045668_6 | PHROG | phrog_706 | NA | unknown function |
| UHGV-2045668_6 | UniRef90 | UniRef90_UPI00156F9D1C | Gp15 family bacteriophage protein | NA |
| UHGV-2045668_6 | eggNOG-mapper | 476272.RUMHYD_01784 | Bacteriophage Gp15 protein | NA |
| UHGV-2045668_6 | Pfam | PF06854 | Bacteriophage Gp15 protein | Phage_Gp15 |
| UHGV-2045668_6 | Structural annotation | PF06854 | NA | NA |
| UHGV-2045668_7 | PHROG | phrog_11299 | NA | unknown function |
| UHGV-2045668_7 | eggNOG-mapper | 33035.JPJF01000106_gene3125 | NA | NA |
| UHGV-2045668_7 | Structural annotation | PF10666 | NA | NA |
| UHGV-2045668_8 | PHROG | phrog_3099 | NA | unknown function |
| UHGV-2045668_8 | eggNOG-mapper | 476272.RUMHYD_01782 | NA | NA |
| UHGV-2045668_8 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-2045668_9 | PHROG | phrog_3266 | tail completion | connector |
| UHGV-2045668_9 | eggNOG-mapper | 476272.RUMHYD_01781 | NA | NA |
| UHGV-2045668_9 | Structural annotation | PF12691 | NA | NA |
| UHGV-2045668_10 | PHROG | phrog_556 | minor head protein | head and packaging |
| UHGV-2045668_10 | UniRef90 | UniRef90_UPI000E4989EB | minor capsid protein | NA |
| UHGV-2045668_10 | eggNOG-mapper | 476272.RUMHYD_01780 | NA | NA |
| UHGV-2045668_10 | Pfam | PF11114 | Minor capsid protein | Minor_capsid_2 |
| UHGV-2045668_10 | Structural annotation | PF11114 | NA | NA |
| UHGV-2045668_11 | PHROG | phrog_3366 | NA | unknown function |
| UHGV-2045668_11 | eggNOG-mapper | 476272.RUMHYD_01779 | NA | NA |
| UHGV-2045668_11 | Structural annotation | PF20536, COG5614 | NA | NA |
| UHGV-2045668_13 | PHROG | phrog_541 | head-tail adaptor | connector |
| UHGV-2045668_13 | eggNOG-mapper | 476272.RUMHYD_01778 | NA | NA |
| UHGV-2045668_15 | UniRef90 | UniRef90_A0A0M2NI16 | S-l_SbsC_C domain-containing protein | NA |
| UHGV-2045668_15 | Structural annotation | PF11651, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-2045668_16 | PHROG | phrog_194 | head scaffolding protein | head and packaging |
| UHGV-2045668_16 | eggNOG-mapper | 397290.C810_05223 | Phage minor structural protein GP20 | NA |
| UHGV-2045668_16 | Pfam | PF06810 | Phage minor structural protein GP20 | Phage_GP20 |
| UHGV-2045668_16 | Structural annotation | PF06810 | NA | NA |
| UHGV-2045668_17 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-2045668_17 | UniRef90 | UniRef90_A0A373MXM0 | Phage capsid protein | NA |
| UHGV-2045668_17 | eggNOG-mapper | 476272.RUMHYD_01761 | Phage minor capsid protein 2 | NA |
| UHGV-2045668_17 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-2045668_17 | COG | COG2369 | NA | NA |
| UHGV-2045668_17 | Structural annotation | PF06152 | NA | NA |
| UHGV-2045668_19 | PHROG | phrog_2428 | NA | unknown function |
| UHGV-2045668_19 | UniRef90 | UniRef90_A0A396QA65 | ABC transporter ATPase | NA |
| UHGV-2045668_19 | eggNOG-mapper | 632245.CLP_1645 | NA | NA |
| UHGV-2045668_19 | dbAPIS | APIS024 | Tad1 proteins are not an enzymes, but are 'sponges' that bind and sequester the immune signaling molecule (cyclic ADP-ribose or gcADPR) produced by TIR-domain proteins, thus decoupling phage sensing from immune effector activation and rendering Thoeris inactive. | NA |
| UHGV-2045668_20 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-2045668_20 | UniRef90 | UniRef90_A0A373MX10 | NA | NA |
| UHGV-2045668_20 | eggNOG-mapper | 457412.RSAG_01107 | NA | NA |
| UHGV-2045668_20 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-2045668_20 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-2045668_20 | Structural annotation | PF11195 | NA | NA |
| UHGV-2045668_21 | PHROG | phrog_1233 | NA | unknown function |
| UHGV-2045668_21 | eggNOG-mapper | 411490.ANACAC_00786 | NA | NA |
| UHGV-2045668_21 | Structural annotation | PF13058 | NA | NA |
| UHGV-2045668_22 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-2045668_22 | UniRef90 | UniRef90_A0A173R9C0 | Phage portal protein, putative, A118 family | NA |
| UHGV-2045668_22 | eggNOG-mapper | 476272.RUMHYD_01758 | phage minor capsid protein | NA |
| UHGV-2045668_22 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-2045668_23 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-2045668_23 | PHROG | phrog_10250 | NA | unknown function |
| UHGV-2045668_23 | UniRef90 | UniRef90_A0A373MY72 | PBSX family phage terminase large subunit | NA |
| UHGV-2045668_23 | eggNOG-mapper | 397290.C810_05187 | Phage terminase large subunit | NA |
| UHGV-2045668_23 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-2045668_23 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-2045668_23 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-2045668_23 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-2045668_24 | KOfam | K07474 | xtmA; phage terminase small subunit | NA |
| UHGV-2045668_24 | PHROG | phrog_51 | terminase small subunit | head and packaging |
| UHGV-2045668_24 | UniRef90 | UniRef90_A0A373MWB9 | Terminase small subunit | NA |
| UHGV-2045668_24 | eggNOG-mapper | 1235800.C819_00494 | Terminase small subunit | NA |
| UHGV-2045668_24 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-2045668_24 | COG | COG3728 | Phage terminase, small subunit | NA |
| UHGV-2045668_24 | Structural annotation | PF03592, COG3728 | NA | NA |
| UHGV-2045668_25 | PHROG | phrog_9479 | NA | unknown function |
| UHGV-2045668_25 | eggNOG-mapper | 633697.EubceDRAFT1_2041 | NA | NA |
| UHGV-2045668_25 | Structural annotation | PF15529 | NA | NA |
| UHGV-2045668_27 | PHROG | phrog_8680 | NA | unknown function |
| UHGV-2045668_27 | UniRef90 | UniRef90_A0A373MX42 | NA | NA |
| UHGV-2045668_27 | eggNOG-mapper | 411470.RUMGNA_02208 | NA | NA |
| UHGV-2045668_27 | Pfam | PF14386 | NA | DUF4417 |
| UHGV-2045668_27 | Structural annotation | PF14386 | NA | NA |
| UHGV-2045668_28 | Structural annotation | PF17224, COG3354 | NA | NA |
| UHGV-2045668_29 | eggNOG-mapper | 476272.RUMHYD_01751 | NA | NA |
| UHGV-2045668_33 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-2045668_33 | UniRef90 | UniRef90_A0A373MXN9 | YopX domain-containing protein | NA |
| UHGV-2045668_33 | eggNOG-mapper | 457412.RSAG_01162 | YopX protein | NA |
| UHGV-2045668_33 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-2045668_33 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-2045668_34 | PHROG | phrog_22292 | NA | unknown function |
| UHGV-2045668_35 | PHROG | phrog_20593 | NA | unknown function |
| UHGV-2045668_35 | eggNOG-mapper | 483218.BACPEC_01161 | NA | NA |
| UHGV-2045668_36 | PHROG | phrog_924 | NA | unknown function |
| UHGV-2045668_36 | UniRef90 | UniRef90_A0A373MXP0 | NA | NA |
| UHGV-2045668_36 | eggNOG-mapper | 742723.HMPREF9477_00919 | NA | NA |
| UHGV-2045668_36 | Pfam | PF04448 | NA | DUF551 |
| UHGV-2045668_37 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-2045668_37 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-2045668_37 | UniRef90 | UniRef90_UPI0018A9016D | NA | NA |
| UHGV-2045668_37 | eggNOG-mapper | 1304880.JAGB01000002_gene2045 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-2045668_37 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-2045668_37 | Pfam | PF04448 | NA | DUF551 |
| UHGV-2045668_37 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-2045668_38 | eggNOG-mapper | 887325.HMPREF0381_0090 | NA | NA |
| UHGV-2045668_39 | PHROG | phrog_26445 | NA | unknown function |
| UHGV-2045668_39 | UniRef90 | UniRef90_UPI001EDD5E1E | Trp family transcriptional regulator | NA |
| UHGV-2045668_39 | eggNOG-mapper | 742765.HMPREF9457_02112 | NA | NA |
| UHGV-2045668_39 | Structural annotation | PF00196 | NA | NA |
| UHGV-2045668_40 | PHROG | phrog_25456 | NA | unknown function |
| UHGV-2045668_43 | PHROG | phrog_9822 | NA | unknown function |
| UHGV-2045668_46 | PHROG | phrog_17183 | NA | unknown function |
| UHGV-2045668_46 | eggNOG-mapper | 1403313.AXBR01000024_gene4694 | NA | NA |
| UHGV-2045668_47 | PHROG | phrog_4400 | NA | unknown function |
| UHGV-2045668_47 | eggNOG-mapper | 357809.Cphy_2990 | NA | NA |
| UHGV-2045668_48 | PHROG | phrog_4400 | NA | unknown function |
| UHGV-2045668_48 | eggNOG-mapper | 357809.Cphy_2990 | NA | NA |
| UHGV-2045668_49 | PHROG | phrog_31560 | NA | unknown function |
| UHGV-2045668_49 | eggNOG-mapper | 796945.HMPREF1145_2028 | NA | NA |
| UHGV-2045668_51 | PHROG | phrog_15077 | NA | unknown function |
| UHGV-2045668_51 | eggNOG-mapper | 742740.HMPREF9474_03494 | NA | NA |
| UHGV-2045668_55 | UniRef90 | UniRef90_A0A373MX33 | NA | NA |
| UHGV-2045668_55 | Pfam | PF04448 | NA | DUF551 |
| UHGV-2045668_55 | Structural annotation | PF04448, NF041588 | NA | NA |
| UHGV-2045668_56 | Structural annotation | PF09889, MF_00649, NF001638, COG4068 | NA | NA |
| UHGV-2045668_57 | PHROG | phrog_2514 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-2045668_57 | UniRef90 | UniRef90_B0NA44 | Phg_2220_C domain-containing protein | NA |
| UHGV-2045668_57 | eggNOG-mapper | 658655.HMPREF0988_00869 | Transcriptional regulator | NA |
| UHGV-2045668_57 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-2045668_57 | Structural annotation | PF08222, NF033788, COG4901 | NA | NA |
| UHGV-2045668_58 | KOfam | K07451 | mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] | NA |
| UHGV-2045668_58 | PHROG | phrog_119 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-2045668_58 | UniRef90 | UniRef90_UPI0018AA8B0B | HNH endonuclease | NA |
| UHGV-2045668_58 | eggNOG-mapper | 315730.BcerKBAB4_3417 | regulation of methylation-dependent chromatin silencing | NA |
| UHGV-2045668_58 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-2045668_58 | COG | COG3440 | Predicted restriction endonuclease | NA |
| UHGV-2045668_59 | PHROG | phrog_244 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-2045668_59 | eggNOG-mapper | 1280692.AUJL01000025_gene2095 | NA | NA |
| UHGV-2045668_59 | Structural annotation | PF01870, MF_01490, NF040854, COG1591 | NA | NA |
| UHGV-2045668_60 | PHROG | phrog_2113 | NA | unknown function |
| UHGV-2045668_60 | UniRef90 | UniRef90_A0A357NGS2 | HTH_11 domain-containing protein | NA |
| UHGV-2045668_60 | Structural annotation | PF21715 | NA | NA |
| UHGV-2045668_61 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-2045668_61 | eggNOG-mapper | 411470.RUMGNA_02194 | NA | NA |
| UHGV-2045668_61 | Structural annotation | PF05772, NF007281 | NA | NA |
| UHGV-2045668_62 | PHROG | phrog_659 | Sak-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-2045668_62 | UniRef90 | UniRef90_UPI0006D01DEB | NA | NA |
| UHGV-2045668_62 | eggNOG-mapper | 33035.JPJF01000135_gene5082 | NA | NA |
| UHGV-2045668_62 | Pfam | PF06378 | NA | DUF1071 |
| UHGV-2045668_62 | Structural annotation | PF06378, TIGR00607, COG5055 | NA | NA |
| UHGV-2045668_63 | PHROG | phrog_30234 | NA | unknown function |
| UHGV-2045668_63 | eggNOG-mapper | 33035.JPJF01000071_gene4461 | NA | NA |
| UHGV-2045668_67 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-2045668_67 | UniRef90 | UniRef90_UPI0018AA5D9A | helix-turn-helix transcriptional regulator | NA |
| UHGV-2045668_67 | eggNOG-mapper | 12417.Q9T1J3_9CAUD | sequence-specific DNA binding | NA |
| UHGV-2045668_67 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-2045668_67 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-2045668_68 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-2045668_68 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-2045668_68 | UniRef90 | UniRef90_A0A3A6GF44 | XRE family transcriptional regulator | NA |
| UHGV-2045668_68 | eggNOG-mapper | 1235802.C823_04750 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-2045668_68 | Pfam | PF12844 | Helix-turn-helix domain | HTH_19 |
| UHGV-2045668_68 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-2045668_68 | Structural annotation | PF12844, NF041951, COG1396 | NA | NA |
| UHGV-2045668_69 | PHROG | phrog_87 | metallo-protease | other |
| UHGV-2045668_69 | UniRef90 | UniRef90_A0A373MWI1 | ImmA/IrrE family metallo-endopeptidase | NA |
| UHGV-2045668_69 | eggNOG-mapper | 1235802.C823_04751 | IrrE N-terminal-like domain | NA |
| UHGV-2045668_69 | Pfam | PF06114 | IrrE N-terminal-like domain | Peptidase_M78 |
| UHGV-2045668_69 | COG | COG2856 | Zn-dependent peptidase ImmA, M78 family | NA |
| UHGV-2045668_69 | Structural annotation | PF06114, COG2856 | NA | NA |
| UHGV-2045668_70 | UniRef90 | UniRef90_UPI001D017E00 | zinc ribbon domain-containing protein | NA |
| UHGV-2045668_70 | Pfam | PF13240 | zinc-ribbon domain | zinc_ribbon_2 |
| UHGV-2045668_71 | PHROG | phrog_806 | NA | unknown function |
| UHGV-2045668_71 | UniRef90 | UniRef90_UPI0006C1B925 | NA | NA |
| UHGV-2045668_71 | eggNOG-mapper | 397290.C810_05150 | NA | NA |
| UHGV-2045668_71 | Pfam | PF11611 | NA | DUF4352 |
| UHGV-2045668_71 | Structural annotation | PF11611, MF_00791, NF041178, COG2967 | NA | NA |
| UHGV-2045668_73 | KOfam | K14059 | int; integrase | NA |
| UHGV-2045668_73 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-2045668_73 | UniRef90 | UniRef90_A0A414P9D4 | Site-specific integrase | NA |
| UHGV-2045668_73 | eggNOG-mapper | 1280698.AUJS01000007_gene999 | Phage integrase family | NA |
| UHGV-2045668_73 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-2045668_73 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-2045668_73 | Structural annotation | PF00589, PF14659, MF_02055, TIGR02224, COG4974 | NA | NA |