vOTU-019103

Overview

vOTU representative UHGV-1451962

No. of genomes 5

Genome length 137,669 bps

Completeness 82.63% (medium-quality)

Host Escherichia coli

Prediction confidence Confident

vOTU information
vOTU ID	vOTU-019103
Number of genomes	5
Taxonomy (ICTV)	Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes
Taxonomy (UHGV)	vFAM-00044 › vSUBFAM-01005 › vGENUS-18370 › vSUBGEN-51498 › vOTU-019103
Host taxonomy	Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Host range breadth	Species
Host prediction method	CRISPR
Lifestyle	Lytic (evidence: BACPHLIP)

Representative genome
Genome ID	UHGV-1451962
BioSample	SAMEA3664861
Genome length	137,669 bps
CheckV completeness	82.63% (medium-quality)
CheckV contamination	0.00%
CDS count	166
CDS density	86.38%
tRNA count	16
Integrase	No
Viral confidence	Confident

Representative genome content

Select view: Genome viewer Functional annotation

Functional annotation

Gene ID	Reference	Reference ID	Information	Category
UHGV-1451962_3	Structural annotation	PF00679, MF_01515, NF003194, COG4843	NA	NA
UHGV-1451962_7	Pfam	PF10544	T5orf172 domain	T5orf172
UHGV-1451962_7	Structural annotation	PF01541, MF_01029, COG2827	NA	NA
UHGV-1451962_9	Structural annotation	PF07106, MF_01177, NF033788, COG0640	NA	NA
UHGV-1451962_11	KOfam	K04769	spoVT; AbrB family transcriptional regulator, stage V sporulation protein T	NA
UHGV-1451962_11	PHROG	phrog_4681	antitoxin from a toxin-antitoxin system	moron, auxiliary metabolic gene and host takeover
UHGV-1451962_11	UniRef90	UniRef90_A0A1B2DFL3	Stage V sporulation protein T	NA
UHGV-1451962_11	eggNOG-mapper	411473.RUMCAL_01244	stage V sporulation protein T	NA
UHGV-1451962_11	Pfam	PF04014	Antidote-toxin recognition MazE, bacterial antitoxin	MazE_antitoxin
UHGV-1451962_11	NCBIFam	TIGR01439.1	transcriptional regulator, AbrB family	NA
UHGV-1451962_11	COG	COG2002	Bifunctional DNA-binding transcriptional regulator of stationary/sporulation/toxin gene expression and antitoxin component of the YhaV-PrlF toxin-antitoxin module	NA
UHGV-1451962_11	Structural annotation	PF04014, PF08962, TIGR02851, COG2002	NA	NA
UHGV-1451962_14	Structural annotation	PF20714, MF_01909, NF007467, COG4738	NA	NA
UHGV-1451962_15	PHROG	phrog_20187	NA	unknown function
UHGV-1451962_15	Structural annotation	PF03104, MF_00045, TIGR00573, COG1949	NA	NA
UHGV-1451962_16	Structural annotation	PF11019, MF_01022, NF003937, COG4502	NA	NA
UHGV-1451962_18	UniRef90	UniRef90_A0A077ZKN1	Ubiquitin interaction motif family protein	NA
UHGV-1451962_26	PHROG	phrog_4182	NA	unknown function
UHGV-1451962_26	UniRef90	UniRef90_A0A172JI79	AAA family ATPase	NA
UHGV-1451962_26	eggNOG-mapper	12336.Q332I4_CBCP	NA	NA
UHGV-1451962_28	KOfam	K01449	cwlJ, sleB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]	NA
UHGV-1451962_28	PHROG	phrog_38339	NA	unknown function
UHGV-1451962_28	UniRef90	UniRef90_A0A2N2CRI8	Hydrolase_2 domain-containing protein	NA
UHGV-1451962_28	eggNOG-mapper	645991.Sgly_0316	sporulation resulting in formation of a cellular spore	NA
UHGV-1451962_28	Pfam	PF07486	Cell Wall Hydrolase	Hydrolase_2
UHGV-1451962_28	COG	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	NA
UHGV-1451962_28	Structural annotation	PF07486, TIGR02869, COG3773	NA	NA
UHGV-1451962_29	KOfam	K01358	clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]	NA
UHGV-1451962_29	PHROG	phrog_94	head maturation protease	head and packaging
UHGV-1451962_29	UniRef90	UniRef90_A0A1V5S6P3	ATP-dependent Clp protease proteolytic subunit	NA
UHGV-1451962_29	eggNOG-mapper	1122915.AUGY01000082_gene6404	Clp protease	NA
UHGV-1451962_29	Pfam	PF00574	Clp protease	CLP_protease
UHGV-1451962_29	COG	COG0740	ATP-dependent protease ClpP, protease subunit	NA
UHGV-1451962_29	Structural annotation	PF00574, MF_00444, NF009205, COG0740	NA	NA
UHGV-1451962_31	PHROG	phrog_5767	sigma factor	transcription regulation
UHGV-1451962_31	UniRef90	UniRef90_A0A345BPU6	HTH DNA binding domain protein	NA
UHGV-1451962_31	eggNOG-mapper	1123239.KB898628_gene3218	NA	NA
UHGV-1451962_32	PHROG	phrog_3314	NA	unknown function
UHGV-1451962_32	eggNOG-mapper	1308863.U5J9N3_9CAUD	NA	NA
UHGV-1451962_33	PHROG	phrog_15503	NA	unknown function
UHGV-1451962_33	eggNOG-mapper	1560313.A0A0D3MT14_9CAUD	NA	NA
UHGV-1451962_33	Structural annotation	PF05876, COG5410	NA	NA
UHGV-1451962_34	PHROG	phrog_59	HNH endonuclease	DNA, RNA and nucleotide metabolism
UHGV-1451962_34	UniRef90	UniRef90_A0A481YSM9	HNH endonuclease	NA
UHGV-1451962_34	eggNOG-mapper	212035.YL245_MIMIV	HNH endonuclease	NA
UHGV-1451962_34	PADLOC	HEase_00016	homing endonuclease	RM
UHGV-1451962_34	Pfam	PF13392	HNH endonuclease	HNH_3
UHGV-1451962_34	Pfam	PF07453	NUMOD1 domain	NUMOD1
UHGV-1451962_35	PHROG	phrog_314	homing endonuclease	DNA, RNA and nucleotide metabolism
UHGV-1451962_35	UniRef90	UniRef90_UPI00093DD291	GIY-YIG nuclease family protein	NA
UHGV-1451962_35	eggNOG-mapper	1354303.M917_2314	NA	NA
UHGV-1451962_35	PADLOC	HEase_00030	homing endonuclease	RM
UHGV-1451962_35	Pfam	PF01541	GIY-YIG catalytic domain	GIY-YIG
UHGV-1451962_35	COG	COG3860	NA	NA
UHGV-1451962_35	Structural annotation	PF01541, PF02796, TIGR01453	NA	NA
UHGV-1451962_36	PHROG	phrog_24618	NA	unknown function
UHGV-1451962_36	UniRef90	UniRef90_A0A0H3V0N0	Putative terminase large subunit	NA
UHGV-1451962_36	eggNOG-mapper	574375.BAGA_05930	Terminase-like family	NA
UHGV-1451962_36	COG	COG4373	Mu-like prophage FluMu protein gp28	NA
UHGV-1451962_36	Structural annotation	PF20441, MF_04146, TIGR01547, COG5362	NA	NA
UHGV-1451962_37	PHROG	phrog_9084	homing endonuclease	DNA, RNA and nucleotide metabolism
UHGV-1451962_37	UniRef90	UniRef90_A0A4R1ASL1	NA	NA
UHGV-1451962_37	eggNOG-mapper	397291.C804_06294	transposase activity	NA
UHGV-1451962_37	COG	COG2963	Transposase InsE and inactivated derivatives	NA
UHGV-1451962_37	Structural annotation	PF18741, MF_04160, NF007294, COG2852	NA	NA
UHGV-1451962_38	PHROG	phrog_2739	portal protein	head and packaging
UHGV-1451962_38	UniRef90	UniRef90_A0A345BPV2	Putative portal protein	NA
UHGV-1451962_38	eggNOG-mapper	665956.HMPREF1032_03237	NA	NA
UHGV-1451962_38	Structural annotation	PF05133, MF_04135, TIGR01537, COG4695	NA	NA
UHGV-1451962_39	PHROG	phrog_3313	NA	unknown function
UHGV-1451962_39	eggNOG-mapper	176279.SERP1627	NA	NA
UHGV-1451962_39	Structural annotation	PF04586, TIGR01543, COG3566	NA	NA
UHGV-1451962_41	PHROG	phrog_4088	NA	unknown function
UHGV-1451962_41	eggNOG-mapper	1541960.KQ78_01850	NA	NA
UHGV-1451962_41	Structural annotation	PF05065, MF_04119, TIGR01554, COG4653	NA	NA
UHGV-1451962_42	PHROG	phrog_30998	NA	unknown function
UHGV-1451962_43	PHROG	phrog_3853	NA	unknown function
UHGV-1451962_43	eggNOG-mapper	1280.SAXN108_2264	NA	NA
UHGV-1451962_44	PHROG	phrog_29637	NA	unknown function
UHGV-1451962_45	PHROG	phrog_31155	NA	unknown function
UHGV-1451962_45	Structural annotation	PF19408, PF11649, NF041894, COG5614	NA	NA
UHGV-1451962_46	PHROG	phrog_6123	virion structural protein	head and packaging
UHGV-1451962_47	PHROG	phrog_4051	NA	unknown function
UHGV-1451962_48	PHROG	phrog_2729	virion structural protein	head and packaging
UHGV-1451962_48	eggNOG-mapper	1163671.JAGI01000002_gene1222	NA	NA
UHGV-1451962_51	PHROG	phrog_30570	NA	unknown function
UHGV-1451962_52	KOfam	K20283	GOLGA4; golgin subfamily A member 4	NA
UHGV-1451962_52	PHROG	phrog_4211	tail length tape measure protein	tail
UHGV-1451962_52	UniRef90	UniRef90_A0A345BQ07	Tail tape protein	NA
UHGV-1451962_52	eggNOG-mapper	1541960.KQ78_01861	nuclear chromosome segregation	NA
UHGV-1451962_52	Pfam	PF10145	Phage-related minor tail protein	PhageMin_Tail
UHGV-1451962_52	NCBIFam	TIGR01760.1	phage tail tape measure protein	NA
UHGV-1451962_52	COG	COG1196	Chromosome segregation ATPase Smc	NA
UHGV-1451962_55	Structural annotation	PF21821, PF12245, PF16974, PF17166, MF_04116, TIGR01633, TIGR03503, COG4228, COG4885	NA	NA
UHGV-1451962_56	PHROG	phrog_32343	NA	unknown function
UHGV-1451962_56	UniRef90	UniRef90_A0A345BPW9	Putative flagellin-like protein	NA
UHGV-1451962_56	eggNOG-mapper	1235800.C819_00529	NA	NA
UHGV-1451962_56	Structural annotation	PF14594, NF033848, COG4379	NA	NA
UHGV-1451962_60	PHROG	phrog_20274	NA	unknown function
UHGV-1451962_60	UniRef90	UniRef90_UPI001C00ACC5	putative ABC transporter permease	NA
UHGV-1451962_60	eggNOG-mapper	693746.OBV_22690	NA	NA
UHGV-1451962_60	Pfam	PF06541	Putative ABC-transporter type IV	ABC_trans_CmpB
UHGV-1451962_60	COG	COG4905	NA	NA
UHGV-1451962_60	Structural annotation	PF06541, COG4905	NA	NA
UHGV-1451962_61	eggNOG-mapper	1203606.HMPREF1526_00965	NA	NA
UHGV-1451962_61	Structural annotation	PF14301	NA	NA
UHGV-1451962_62	KOfam	K00986	ltrA; RNA-directed DNA polymerase [EC:2.7.7.49]	NA
UHGV-1451962_62	PHROG	phrog_1423	Reverse transcriptase	DNA, RNA and nucleotide metabolism
UHGV-1451962_62	UniRef90	UniRef90_A0A1C5ZG36	Retron-type reverse transcriptase	NA
UHGV-1451962_62	eggNOG-mapper	665950.HMPREF1025_01556	Reverse transcriptase (RNA-dependent DNA polymerase)	NA
UHGV-1451962_62	PADLOC	icity0040	RT (reverse transcriptase)	CRISPR-CAS
UHGV-1451962_62	Pfam	PF00078	Reverse transcriptase (RNA-dependent DNA polymerase)	RVT_1
UHGV-1451962_62	COG	COG3344	Retron-type reverse transcriptase	NA
UHGV-1451962_62	Structural annotation	PF00078, MF_01390, TIGR04416, COG3344	NA	NA
UHGV-1451962_64	PHROG	phrog_37900	NA	unknown function
UHGV-1451962_64	UniRef90	UniRef90_UPI00110725F0	NA	NA
UHGV-1451962_64	eggNOG-mapper	552398.HMPREF0866_03098	NA	NA
UHGV-1451962_64	Pfam	PF07523	Bacterial Ig-like domain (group 3)	Big_3
UHGV-1451962_64	COG	COG3827	Cell pole-organizing protein PopZ	NA
UHGV-1451962_64	Structural annotation	PF19789, PF19190, MF_04116, NF033639, COG1470	NA	NA
UHGV-1451962_67	PHROG	phrog_2310	NA	unknown function
UHGV-1451962_68	KOfam	K14060	pinR; putative DNA-invertase from lambdoid prophage Rac	NA
UHGV-1451962_68	PHROG	phrog_125	DNA invertase	DNA, RNA and nucleotide metabolism
UHGV-1451962_68	UniRef90	UniRef90_UPI00118516F8	recombinase family protein	NA
UHGV-1451962_68	eggNOG-mapper	742738.HMPREF9460_01133	Resolvase, N terminal domain	NA
UHGV-1451962_68	Pfam	PF00239	Resolvase, N terminal domain	Resolvase
UHGV-1451962_68	COG	COG1961	Site-specific DNA recombinase SpoIVCA/DNA invertase PinE	NA
UHGV-1451962_68	Structural annotation	PF00239, PF02796, NF009949, COG1961	NA	NA
UHGV-1451962_69	PHROG	phrog_13712	holin	lysis
UHGV-1451962_69	eggNOG-mapper	1203606.HMPREF1526_00252	NA	NA
UHGV-1451962_71	eggNOG-mapper	476272.RUMHYD_01953	NA	NA
UHGV-1451962_72	PHROG	phrog_16490	NA	unknown function
UHGV-1451962_72	eggNOG-mapper	658655.HMPREF0988_00917	NA	NA
UHGV-1451962_73	PHROG	phrog_20016	NA	unknown function
UHGV-1451962_73	UniRef90	UniRef90_A0A345BPX4	Carbohydrate binding domain/collagen triple helix repeat protein	NA
UHGV-1451962_73	eggNOG-mapper	1226322.HMPREF1545_00077	NA	NA
UHGV-1451962_73	Structural annotation	PF18573, NF033147	NA	NA
UHGV-1451962_74	eggNOG-mapper	658655.HMPREF0988_00915	NA	NA
UHGV-1451962_75	PHROG	phrog_1233	NA	unknown function
UHGV-1451962_75	UniRef90	UniRef90_A0A345BPX6	Metal-dependent hydrolase	NA
UHGV-1451962_75	eggNOG-mapper	658655.HMPREF0988_00914	NA	NA
UHGV-1451962_76	PHROG	phrog_4105	NA	unknown function
UHGV-1451962_76	eggNOG-mapper	1260356.D920_01755	NA	NA
UHGV-1451962_77	KOfam	K01159	ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]	NA
UHGV-1451962_77	PHROG	phrog_827	Holliday junction resolvase	DNA, RNA and nucleotide metabolism
UHGV-1451962_77	UniRef90	UniRef90_A0A7K3Z7M4	Crossover junction endodeoxyribonuclease RuvC	NA
UHGV-1451962_77	eggNOG-mapper	871968.DESME_08990	NA	NA
UHGV-1451962_77	Structural annotation	PF07066, MF_00034, NF000711, COG0817	NA	NA
UHGV-1451962_78	KOfam	K01520	dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]	NA
UHGV-1451962_78	PHROG	phrog_135	dUTPase	DNA, RNA and nucleotide metabolism
UHGV-1451962_78	UniRef90	UniRef90_A0A843FKH7	dUTPase domain-containing protein (Fragment)	NA
UHGV-1451962_78	eggNOG-mapper	1045854.WKK_04625	dUTPase	NA
UHGV-1451962_78	Pfam	PF00692	dUTPase	dUTPase
UHGV-1451962_78	COG	COG0756	dUTP pyrophosphatase (dUTPase)	NA
UHGV-1451962_78	Structural annotation	PF00692, MF_00116, NF010561, COG0756	NA	NA
UHGV-1451962_79	Structural annotation	PF10750, MF_01122, TIGR00285, COG1581	NA	NA
UHGV-1451962_80	Structural annotation	PF16921, MF_01234, NF001026, COG4820	NA	NA
UHGV-1451962_82	KOfam	K04068	nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4]	NA
UHGV-1451962_82	PHROG	phrog_626	anaerobic ribonucleotide reductase small subunit	DNA, RNA and nucleotide metabolism
UHGV-1451962_82	UniRef90	UniRef90_UPI001651A4D2	anaerobic ribonucleoside-triphosphate reductase activating protein	NA
UHGV-1451962_82	eggNOG-mapper	1292035.H476_3551	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	NA
UHGV-1451962_82	Pfam	PF13353	4Fe-4S single cluster domain	Fer4_12
UHGV-1451962_82	NCBIFam	TIGR02491.1	anaerobic ribonucleoside-triphosphate reductase activating protein	NA
UHGV-1451962_82	COG	COG0602	Organic radical activating enzyme NrdG/QueE	NA
UHGV-1451962_82	Structural annotation	PF13353, MF_00917, TIGR02491, COG0602	NA	NA
UHGV-1451962_85	KOfam	K21636	nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]	NA
UHGV-1451962_85	PHROG	phrog_487	NrdD-like anaerobic ribonucleotide reductase large subunit	moron, auxiliary metabolic gene and host takeover
UHGV-1451962_85	UniRef90	UniRef90_A0A3R6SNB8	Anaerobic ribonucleoside-triphosphate reductase	NA
UHGV-1451962_85	eggNOG-mapper	1304866.K413DRAFT_4593	Ribonucleoside-triphosphate reductase	NA
UHGV-1451962_85	Pfam	PF03477	ATP cone domain	ATP-cone
UHGV-1451962_85	Pfam	PF13597	Anaerobic ribonucleoside-triphosphate reductase	NRDD
UHGV-1451962_85	NCBIFam	TIGR02487.1	anaerobic ribonucleoside-triphosphate reductase	NA
UHGV-1451962_85	COG	COG1328	Anaerobic ribonucleoside-triphosphate reductase	NA
UHGV-1451962_85	Structural annotation	PF13597, PF03477, MF_00440, NF005497, COG1328	NA	NA
UHGV-1451962_86	KOfam	K00942	gmk, GUK1; guanylate kinase [EC:2.7.4.8]	NA
UHGV-1451962_86	PHROG	phrog_1815	guanylate kinase	other
UHGV-1451962_86	UniRef90	UniRef90_A0A843FCP8	Guanylate kinase-like domain-containing protein	NA
UHGV-1451962_86	eggNOG-mapper	1410631.JHWZ01000001_gene1084	Guanylate kinase homologues.	NA
UHGV-1451962_86	Pfam	PF00625	Guanylate kinase	Guanylate_kin
UHGV-1451962_86	COG	COG0194	Guanylate kinase	NA
UHGV-1451962_86	Structural annotation	PF00625, MF_00328, NF011324, COG0194	NA	NA
UHGV-1451962_87	KOfam	K02337	dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]	NA
UHGV-1451962_87	PHROG	phrog_405	DNA polymerase	DNA, RNA and nucleotide metabolism
UHGV-1451962_87	UniRef90	UniRef90_A0A858MXR6	DNA-directed DNA polymerase	NA
UHGV-1451962_87	eggNOG-mapper	742735.HMPREF9467_00895	DNA polymerase III alpha subunit	NA
UHGV-1451962_87	Pfam	PF02811	PHP domain	PHP
UHGV-1451962_87	Pfam	PF07733	Bacterial DNA polymerase III alpha NTPase domain	DNA_pol3_alpha
UHGV-1451962_87	Pfam	PF17657	Bacterial DNA polymerase III alpha subunit finger domain	DNA_pol3_finger
UHGV-1451962_87	Pfam	PF14579	Helix-hairpin-helix motif	HHH_6
UHGV-1451962_87	NCBIFam	TIGR00594.1	DNA polymerase III subunit alpha	NA
UHGV-1451962_87	COG	COG0587	DNA polymerase III, alpha subunit	NA
UHGV-1451962_87	Structural annotation	PF07733, PF02811, PF17657, PF14579, MF_01902, NF005617, COG0587	NA	NA
UHGV-1451962_88	KOfam	K03581	recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]	NA
UHGV-1451962_88	PHROG	phrog_325	Dda-like helicase	DNA, RNA and nucleotide metabolism
UHGV-1451962_88	UniRef90	UniRef90_A0A843GQ82	AAA family ATPase	NA
UHGV-1451962_88	eggNOG-mapper	1121085.AUCI01000012_gene2815	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	NA
UHGV-1451962_88	PADLOC	cluster10	RecD_0_IVD	CRISPR-CAS
UHGV-1451962_88	Pfam	PF13604	AAA domain	AAA_30
UHGV-1451962_88	Pfam	PF13538	UvrD-like helicase C-terminal domain	UvrD_C_2
UHGV-1451962_88	COG	COG0507	ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V)	NA
UHGV-1451962_88	Structural annotation	PF13604, MF_01488, TIGR01448, COG0507	NA	NA
UHGV-1451962_90	KOfam	K07462	recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]	NA
UHGV-1451962_90	PHROG	phrog_2484	RecJ-like ssDNA exonuclease	DNA, RNA and nucleotide metabolism
UHGV-1451962_90	UniRef90	UniRef90_A0A843FU26	DHH family phosphoesterase	NA
UHGV-1451962_90	eggNOG-mapper	224308.BSU20350	Single-stranded-DNA-specific exonuclease RecJ	NA
UHGV-1451962_90	Pfam	PF01368	DHH family	DHH
UHGV-1451962_90	Pfam	PF17768	RecJ OB domain	RecJ_OB
UHGV-1451962_90	COG	COG0608	ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation	NA
UHGV-1451962_90	Structural annotation	PF17768, PF02272, MF_00207, TIGR00644, COG0608	NA	NA
UHGV-1451962_91	KOfam	K02316	dnaG; DNA primase [EC:2.7.7.101]	NA
UHGV-1451962_91	PHROG	phrog_47	DNA primase	DNA, RNA and nucleotide metabolism
UHGV-1451962_91	UniRef90	UniRef90_A0A345BPU0	DNA primase	NA
UHGV-1451962_91	eggNOG-mapper	224308.BSU20360	DNA primase activity	NA
UHGV-1451962_91	COG	COG0358	DNA primase (bacterial type)	NA
UHGV-1451962_91	Structural annotation	PF01807, PF19898, MF_00974, NF006382, COG0358	NA	NA
UHGV-1451962_93	KOfam	K02314	dnaB; replicative DNA helicase [EC:5.6.2.3]	NA
UHGV-1451962_93	PHROG	phrog_19	DnaB-like replicative helicase	DNA, RNA and nucleotide metabolism
UHGV-1451962_93	UniRef90	UniRef90_A0A843FVR3	DNA helicase	NA
UHGV-1451962_93	eggNOG-mapper	537007.BLAHAN_05495	DnaB-like helicase C terminal domain	NA
UHGV-1451962_93	Pfam	PF00772	DnaB-like helicase N terminal domain	DnaB
UHGV-1451962_93	Pfam	PF03796	DnaB-like helicase C terminal domain	DnaB_C
UHGV-1451962_93	COG	COG0305	Replicative DNA helicase	NA
UHGV-1451962_93	Structural annotation	PF03796, PF00772, MF_04155, TIGR00665, COG0305	NA	NA
UHGV-1451962_94	PHROG	phrog_4680	NA	unknown function
UHGV-1451962_94	UniRef90	UniRef90_A0A3S4N9I4	NA	NA
UHGV-1451962_94	eggNOG-mapper	1280.SAXN108_2226	NA	NA
UHGV-1451962_95	PHROG	phrog_124	Sak4-like ssDNA annealing protein	DNA, RNA and nucleotide metabolism
UHGV-1451962_95	UniRef90	UniRef90_A0A843FNM7	ATP-binding protein	NA
UHGV-1451962_95	eggNOG-mapper	1541960.KQ78_01919	Belongs to the helicase family. UvrD subfamily	NA
UHGV-1451962_95	Pfam	PF13479	AAA domain	AAA_24
UHGV-1451962_95	COG	COG2887	RecB family exonuclease	NA
UHGV-1451962_95	Structural annotation	PF13479, MF_00350, TIGR01618, COG0468	NA	NA
UHGV-1451962_96	Structural annotation	PF00436, PF19649, MF_00984, NF004476, COG2965	NA	NA
UHGV-1451962_97	KOfam	K03465	thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148]	NA
UHGV-1451962_97	PHROG	phrog_85	thymidylate synthase	DNA, RNA and nucleotide metabolism
UHGV-1451962_97	UniRef90	UniRef90_A0A7X2NTD7	FAD-dependent thymidylate synthase	NA
UHGV-1451962_97	eggNOG-mapper	1282887.AUJG01000001_gene1906	thymidylate synthase (FAD) activity	NA
UHGV-1451962_97	Pfam	PF02511	Thymidylate synthase complementing protein	Thy1
UHGV-1451962_97	COG	COG1351	Thymidylate synthase ThyX, FAD-dependent family	NA
UHGV-1451962_97	Structural annotation	PF02511, MF_01408, TIGR02170, COG1351	NA	NA
UHGV-1451962_98	UniRef90	UniRef90_A0A345BPT3	SarR-like protein	NA
UHGV-1451962_98	Structural annotation	PF04182, MF_01909, NF040939, COG1675	NA	NA
UHGV-1451962_100	KOfam	K10747	LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]	NA
UHGV-1451962_100	PHROG	phrog_114	ATP-dependent DNA ligase	DNA, RNA and nucleotide metabolism
UHGV-1451962_100	UniRef90	UniRef90_A0A345BPZ1	DNA ligase	NA
UHGV-1451962_100	eggNOG-mapper	1121121.KB894295_gene4492	dna ligase	NA
UHGV-1451962_100	Pfam	PF01068	ATP dependent DNA ligase domain	DNA_ligase_A_M
UHGV-1451962_100	Pfam	PF04679	ATP dependent DNA ligase C terminal region	DNA_ligase_A_C
UHGV-1451962_100	COG	COG1793	ATP-dependent DNA ligase	NA
UHGV-1451962_100	Structural annotation	PF01068, MF_00407, TIGR02779, COG1793	NA	NA
UHGV-1451962_101	KOfam	K02469	gyrA; DNA gyrase subunit A [EC:5.6.2.2]	NA
UHGV-1451962_101	PHROG	phrog_551	DNA topoisomerase II	DNA, RNA and nucleotide metabolism
UHGV-1451962_101	UniRef90	UniRef90_A0A832SNJ2	DNA topoisomerase (ATP-hydrolyzing)	NA
UHGV-1451962_101	eggNOG-mapper	720554.Clocl_4221	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	NA
UHGV-1451962_101	Pfam	PF00521	DNA gyrase/topoisomerase IV, subunit A	DNA_topoisoIV
UHGV-1451962_101	Pfam	PF03989	DNA gyrase C-terminal domain, beta-propeller	DNA_gyraseA_C
UHGV-1451962_101	COG	COG0188	DNA gyrase/topoisomerase IV, subunit A	NA
UHGV-1451962_101	Structural annotation	PF00521, PF03989, MF_01897, NF004043, COG0188	NA	NA
UHGV-1451962_102	KOfam	K02470	gyrB; DNA gyrase subunit B [EC:5.6.2.2]	NA
UHGV-1451962_102	PHROG	phrog_543	DNA topoisomerase II large subunit	DNA, RNA and nucleotide metabolism
UHGV-1451962_102	UniRef90	UniRef90_A0A3B9Z7X0	DNA topoisomerase (ATP-hydrolyzing)	NA
UHGV-1451962_102	eggNOG-mapper	1273103.NM10_03753	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	NA
UHGV-1451962_102	Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	HATPase_c
UHGV-1451962_102	Pfam	PF00204	DNA gyrase B	DNA_gyraseB
UHGV-1451962_102	Pfam	PF01751	Toprim domain	Toprim
UHGV-1451962_102	Pfam	PF00986	DNA gyrase B subunit, carboxyl terminus	DNA_gyraseB_C
UHGV-1451962_102	COG	COG0187	DNA gyrase/topoisomerase IV, subunit B	NA
UHGV-1451962_102	Structural annotation	PF00204, MF_01898, TIGR01059, COG0187	NA	NA
UHGV-1451962_103	KOfam	K03469	rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4]	NA
UHGV-1451962_103	PHROG	phrog_531	Rnase H	DNA, RNA and nucleotide metabolism
UHGV-1451962_103	UniRef90	UniRef90_A0A843FJ64	Ribonuclease H	NA
UHGV-1451962_103	eggNOG-mapper	367737.Abu_1488	RNase H	NA
UHGV-1451962_103	Pfam	PF00075	RNase H	RNase_H
UHGV-1451962_103	COG	COG0328	Ribonuclease HI	NA
UHGV-1451962_103	Structural annotation	PF00075, MF_00042, NF001236, COG0328	NA	NA
UHGV-1451962_105	UniRef90	UniRef90_UPI00195CFCED	C39 family peptidase	NA
UHGV-1451962_105	eggNOG-mapper	397291.C804_01109	Phage lysozyme	NA
UHGV-1451962_105	Pfam	PF13529	Peptidase_C39 like family	Peptidase_C39_2
UHGV-1451962_105	Pfam	PF00395	S-layer homology domain	SLH
UHGV-1451962_105	COG	COG3584	3D (Asp-Asp-Asp) domain, usually in lytic transglycosylases	NA
UHGV-1451962_105	Structural annotation	PF03412, COG4990	NA	NA
UHGV-1451962_106	KOfam	K07175	phoH2; PhoH-like ATPase	NA
UHGV-1451962_106	PHROG	phrog_2765	PhoH-like phosphate starvation-inducible	other
UHGV-1451962_106	UniRef90	UniRef90_A0A416A0G0	PhoH domain-containing protein	NA
UHGV-1451962_106	eggNOG-mapper	1123252.ATZF01000010_gene420	PIN domain	NA
UHGV-1451962_106	Pfam	PF02562	PhoH-like protein	PhoH
UHGV-1451962_106	COG	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	NA
UHGV-1451962_106	Structural annotation	PF02562, NF007827, COG1702	NA	NA
UHGV-1451962_107	PHROG	phrog_4645	endonuclease	DNA, RNA and nucleotide metabolism
UHGV-1451962_107	UniRef90	UniRef90_UPI001CD2380C	LAGLIDADG family homing endonuclease	NA
UHGV-1451962_107	eggNOG-mapper	1321778.HMPREF1982_01005	Participates in initiation and elongation during chromosome replication	NA
UHGV-1451962_107	Pfam	PF14528	LAGLIDADG-like domain	LAGLIDADG_3
UHGV-1451962_107	COG	COG1372	Intein/homing endonuclease	NA
UHGV-1451962_107	Structural annotation	PF03161, PF02796, MF_01420, TIGR00647, TIGR04381, COG1372	NA	NA
UHGV-1451962_108	KOfam	K07175	phoH2; PhoH-like ATPase	NA
UHGV-1451962_108	PHROG	phrog_2765	PhoH-like phosphate starvation-inducible	other
UHGV-1451962_108	UniRef90	UniRef90_A0A1C5UCD2	PhoH-like protein	NA
UHGV-1451962_108	eggNOG-mapper	1541960.KQ78_01838	PIN domain	NA
UHGV-1451962_108	Pfam	PF13638	PIN domain	PIN_4
UHGV-1451962_108	Pfam	PF02562	PhoH-like protein	PhoH
UHGV-1451962_108	COG	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	NA
UHGV-1451962_108	Structural annotation	PF13638, MF_00265, NF010285, COG1875	NA	NA
UHGV-1451962_110	KOfam	K07099	NA	NA
UHGV-1451962_110	PHROG	phrog_547	phosphoesterase	other
UHGV-1451962_110	UniRef90	UniRef90_A0A1I0M725	Calcineurin-like phosphoesterase superfamily protein	NA
UHGV-1451962_110	eggNOG-mapper	1392491.JIAE01000001_gene1129	Calcineurin-like phosphoesterase	NA
UHGV-1451962_110	Pfam	PF12850	Calcineurin-like phosphoesterase superfamily domain	Metallophos_2
UHGV-1451962_110	COG	COG4186	NA	NA
UHGV-1451962_110	Structural annotation	PF12850, MF_00575, NF006988, COG4186	NA	NA
UHGV-1451962_111	PHROG	phrog_6931	NA	unknown function
UHGV-1451962_111	UniRef90	UniRef90_A0A345BPY6	AAA domain protein	NA
UHGV-1451962_111	Pfam	PF13671	AAA domain	AAA_33
UHGV-1451962_111	COG	COG4639	Predicted kinase	NA
UHGV-1451962_111	Structural annotation	PF13671, NF005251, COG4639	NA	NA
UHGV-1451962_112	PHROG	phrog_1257	ribosome associated inhibitor A; zinc finger domain	moron, auxiliary metabolic gene and host takeover
UHGV-1451962_112	Structural annotation	PF00471, MF_00294, TIGR01023, COG0267	NA	NA
UHGV-1451962_114	KOfam	K07313	pphA; serine/threonine protein phosphatase 1 [EC:3.1.3.16]	NA
UHGV-1451962_114	PHROG	phrog_246	NinI-like serine-threonine phosphatase	other
UHGV-1451962_114	UniRef90	UniRef90_A0A1Q9JVZ2	Phosphoesterase	NA
UHGV-1451962_114	eggNOG-mapper	1232447.BAHW02000013_gene664	Calcineurin-like phosphoesterase	NA
UHGV-1451962_114	Pfam	PF00149	Calcineurin-like phosphoesterase	Metallophos
UHGV-1451962_114	COG	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	NA
UHGV-1451962_114	Structural annotation	PF12850, MF_01443, NF007425, COG0622	NA	NA
UHGV-1451962_116	KOfam	K09117	NA	NA
UHGV-1451962_116	PHROG	phrog_1460	tRNA amidotransferase	DNA, RNA and nucleotide metabolism
UHGV-1451962_116	UniRef90	UniRef90_R5QYG3	YqeY-like protein	NA
UHGV-1451962_116	eggNOG-mapper	537007.BLAHAN_05390	NA	NA
UHGV-1451962_116	Pfam	PF09424	Yqey-like protein	YqeY
UHGV-1451962_116	COG	COG1610	NA	NA
UHGV-1451962_116	Structural annotation	PF09424, COG1610	NA	NA
UHGV-1451962_117	PHROG	phrog_968	RNA ligase	DNA, RNA and nucleotide metabolism
UHGV-1451962_117	UniRef90	UniRef90_A0A3G3BVL5	RNA ligase	NA
UHGV-1451962_117	eggNOG-mapper	247156.NFA_39550	RNA ligase	NA
UHGV-1451962_117	Pfam	PF09414	RNA ligase	RNA_ligase
UHGV-1451962_117	Structural annotation	PF21189, PF09414, MF_04150, TIGR02306, COG1423, COG0073	NA	NA
UHGV-1451962_118	Structural annotation	PF13463, MF_01819, NF040939, COG0735	NA	NA
UHGV-1451962_119	KOfam	K06348	kapD; sporulation inhibitor KapD	NA
UHGV-1451962_119	PHROG	phrog_192	DNA polymerase exonuclease subunit	DNA, RNA and nucleotide metabolism
UHGV-1451962_119	UniRef90	UniRef90_UPI0019171D70	exonuclease domain-containing protein	NA
UHGV-1451962_119	PADLOC	cd06127	CAS-I,CAS-II,CAS-III,CAS-IV,CAS-V,CAS-VI; associated	CRISPR-CAS
UHGV-1451962_119	Pfam	PF00929	Exonuclease	RNase_T
UHGV-1451962_119	COG	COG5018	3'-5' exonuclease KapD, inhibitor of KinA-controlled sporulation	NA
UHGV-1451962_119	Structural annotation	PF00929, MF_00977, NF005838, COG5018	NA	NA
UHGV-1451962_122	PHROG	phrog_1649	metallo-phosphoesterase	other
UHGV-1451962_122	UniRef90	UniRef90_A0A843H0H1	Metallophosphoesterase	NA
UHGV-1451962_122	eggNOG-mapper	663278.Ethha_1276	metallophosphoesterase	NA
UHGV-1451962_122	Pfam	PF00149	Calcineurin-like phosphoesterase	Metallophos
UHGV-1451962_122	COG	COG1408	Predicted phosphohydrolase, MPP superfamily	NA
UHGV-1451962_122	Structural annotation	PF14582, MF_00575, TIGR03729, COG2129	NA	NA
UHGV-1451962_123	KOfam	K07074	NA	NA
UHGV-1451962_123	PHROG	phrog_388	nucleotidyltransferase	DNA, RNA and nucleotide metabolism
UHGV-1451962_123	UniRef90	UniRef90_A0A843FSU3	Nucleotidyltransferase domain-containing protein	NA
UHGV-1451962_123	eggNOG-mapper	498761.HM1_0723	Predicted nucleotidyltransferase	NA
UHGV-1451962_123	Pfam	PF10127	RNA repair pathway DNA polymerase beta family	RlaP
UHGV-1451962_123	Structural annotation	PF10127, NF000079, COG3541	NA	NA
UHGV-1451962_124	PHROG	phrog_1479	NA	unknown function
UHGV-1451962_124	eggNOG-mapper	1256908.HMPREF0373_01589	NA	NA
UHGV-1451962_124	Pfam	PF20274	Cyclic-phosphate processing Receiver domain	cREC_REC
UHGV-1451962_124	Structural annotation	PF20274	NA	NA
UHGV-1451962_125	KOfam	K13277	epr; minor extracellular protease Epr [EC:3.4.21.-]	NA
UHGV-1451962_125	UniRef90	UniRef90_UPI000F6408F2	S-layer homology domain-containing protein	NA
UHGV-1451962_125	Pfam	PF00082	Subtilase family	Peptidase_S8
UHGV-1451962_125	Pfam	PF00395	S-layer homology domain	SLH
UHGV-1451962_125	COG	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	NA
UHGV-1451962_125	Structural annotation	PF00395, TIGR03921, COG1404	NA	NA
UHGV-1451962_126	PHROG	phrog_850	RNA-binding protein	DNA, RNA and nucleotide metabolism
UHGV-1451962_126	UniRef90	UniRef90_A0A843FJC6	NA	NA
UHGV-1451962_126	eggNOG-mapper	1541960.KQ78_01972	oxidoreductase activity	NA
UHGV-1451962_126	Pfam	PF11443	NA	DUF2828
UHGV-1451962_126	COG	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	NA
UHGV-1451962_126	Structural annotation	PF11443, MF_01340, COG2304	NA	NA
UHGV-1451962_129	KOfam	K06871	NA	NA
UHGV-1451962_129	PHROG	phrog_1802	radical SAM domain-containing protein	other
UHGV-1451962_129	UniRef90	UniRef90_A0A349HR65	Radical SAM core domain-containing protein	NA
UHGV-1451962_129	eggNOG-mapper	997350.HMPREF9129_1634	Six-Cys-in-45 modification radical SAM protein	NA
UHGV-1451962_129	PADLOC	pVip-lone	Viperins not associated with kinases	Viperin
UHGV-1451962_129	Pfam	PF04055	Radical SAM superfamily	Radical_SAM
UHGV-1451962_129	NCBIFam	TIGR04085.1	SPASM domain-containing protein	NA
UHGV-1451962_129	COG	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	NA
UHGV-1451962_129	Structural annotation	PF04055, MF_00660, TIGR04136, COG0641	NA	NA
UHGV-1451962_130	Structural annotation	PF08962	NA	NA
UHGV-1451962_131	PHROG	phrog_4302	NA	unknown function
UHGV-1451962_131	COG	COG5301	Phage-related tail fiber protein	NA
UHGV-1451962_135	UniRef90	UniRef90_A0A8D9UHD2	Hyaluroniase	NA
UHGV-1451962_135	eggNOG-mapper	357276.EL88_15700	NA	NA
UHGV-1451962_135	Structural annotation	PF18454, PF14262	NA	NA
UHGV-1451962_136	Structural annotation	PF20010	NA	NA
UHGV-1451962_140	UniRef90	UniRef90_A0A0B3BKP6	LIM zinc-binding domain-containing protein	NA
UHGV-1451962_140	eggNOG-mapper	935948.KE386495_gene2241	NA	NA
UHGV-1451962_141	KOfam	K01258	pepT; tripeptide aminopeptidase [EC:3.4.11.4]	NA
UHGV-1451962_141	PHROG	phrog_34186	NA	unknown function
UHGV-1451962_141	UniRef90	UniRef90_A0A843FCH3	M28 family peptidase	NA
UHGV-1451962_141	eggNOG-mapper	935948.KE386495_gene2240	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	NA
UHGV-1451962_141	Pfam	PF04389	Peptidase family M28	Peptidase_M28
UHGV-1451962_141	COG	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	NA
UHGV-1451962_142	Structural annotation	PF02581, MF_02232, TIGR01182, COG0135	NA	NA
UHGV-1451962_143	Structural annotation	PF04182, MF_01586, NF040939, COG0735	NA	NA
UHGV-1451962_144	eggNOG-mapper	411467.BACCAP_03130	NA	NA
UHGV-1451962_156	PHROG	phrog_547	phosphoesterase	other
UHGV-1451962_156	UniRef90	UniRef90_A0A843FNF2	Metallophosphoesterase	NA
UHGV-1451962_156	eggNOG-mapper	1410632.JHWW01000019_gene1481	NA	NA
UHGV-1451962_156	Pfam	PF00149	Calcineurin-like phosphoesterase	Metallophos
UHGV-1451962_156	Structural annotation	MF_00575, TIGR04123, COG4186	NA	NA

All genomes

Genome	vOTU repr.	Length	GC content	CheckV completeness	geNomad score
UHGV-1451962	Yes	137,669 bps	30.97%	82.63%	0.9749
UHGV-1519562	No	130,331 bps	30.94%	81.06%	0.9726
UHGV-1709118	No	61,628 bps	32.34%	40.42%	0.9740
UHGV-1682877	No	67,836 bps	30.45%	39.95%	0.9736
UHGV-1773631	No	18,342 bps	29.99%	11.14%	0.9718