| UHGV-1508176_1 | PHROG | phrog_7854 | endolysin | lysis |
| UHGV-1508176_1 | UniRef90 | UniRef90_A0A373SW30 | MurNAc-LAA domain-containing protein | NA |
| UHGV-1508176_1 | eggNOG-mapper | 411462.DORLON_00764 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1508176_1 | Pfam | PF01520 | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
| UHGV-1508176_1 | Pfam | PF19127 | Choline-binding repeat | Choline_bind_3 |
| UHGV-1508176_1 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1508176_1 | Structural annotation | PF01520, TIGR02883, COG0860, COG5263 | NA | NA |
| UHGV-1508176_2 | PHROG | phrog_18218 | NA | unknown function |
| UHGV-1508176_2 | UniRef90 | UniRef90_A0A373SUI3 | Ribonuclease | NA |
| UHGV-1508176_2 | eggNOG-mapper | 658655.HMPREF0988_02546 | NA | NA |
| UHGV-1508176_2 | Structural annotation | PF06946 | NA | NA |
| UHGV-1508176_3 | PHROG | phrog_1863 | NA | unknown function |
| UHGV-1508176_3 | eggNOG-mapper | 1226322.HMPREF1545_04027 | NA | NA |
| UHGV-1508176_5 | PHROG | phrog_13589 | NA | unknown function |
| UHGV-1508176_5 | eggNOG-mapper | 411460.RUMTOR_01324 | NA | NA |
| UHGV-1508176_6 | PHROG | phrog_13589 | NA | unknown function |
| UHGV-1508176_6 | eggNOG-mapper | 742733.HMPREF9469_05009 | NA | NA |
| UHGV-1508176_7 | PHROG | phrog_31538 | NA | unknown function |
| UHGV-1508176_7 | eggNOG-mapper | 742740.HMPREF9474_02274 | NA | NA |
| UHGV-1508176_8 | PHROG | phrog_15594 | NA | unknown function |
| UHGV-1508176_8 | eggNOG-mapper | 1118055.CAGU01000013_gene763 | NA | NA |
| UHGV-1508176_8 | Structural annotation | PF16640, TIGR04488 | NA | NA |
| UHGV-1508176_9 | PHROG | phrog_25635 | NA | unknown function |
| UHGV-1508176_9 | eggNOG-mapper | 1280698.AUJS01000007_gene1050 | NA | NA |
| UHGV-1508176_9 | Structural annotation | PF20747, NF012201 | NA | NA |
| UHGV-1508176_10 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-1508176_10 | UniRef90 | UniRef90_UPI001F3E20C1 | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-1508176_10 | eggNOG-mapper | 1280698.AUJS01000007_gene1049 | NA | NA |
| UHGV-1508176_10 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-1508176_10 | Structural annotation | PF14594, TIGR01665, COG4379 | NA | NA |
| UHGV-1508176_11 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-1508176_11 | UniRef90 | UniRef90_UPI00156E3DDD | phage tail protein | NA |
| UHGV-1508176_11 | eggNOG-mapper | 1280698.AUJS01000007_gene1048 | NA | NA |
| UHGV-1508176_11 | Structural annotation | PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-1508176_12 | PHROG | phrog_6900 | tail length tape measure protein | tail |
| UHGV-1508176_12 | UniRef90 | UniRef90_A0A174L0T5 | Phage-related protein | NA |
| UHGV-1508176_12 | eggNOG-mapper | 1280698.AUJS01000007_gene1047 | nuclear chromosome segregation | NA |
| UHGV-1508176_12 | COG | COG1511 | NA | NA |
| UHGV-1508176_12 | Structural annotation | PF20155, MF_04138, COG5281 | NA | NA |
| UHGV-1508176_13 | PHROG | phrog_1633 | NA | unknown function |
| UHGV-1508176_13 | UniRef90 | UniRef90_UPI0006C2F0F2 | NA | NA |
| UHGV-1508176_13 | eggNOG-mapper | 1280698.AUJS01000007_gene1046 | NA | NA |
| UHGV-1508176_13 | Pfam | PF17318 | NA | DUF5361 |
| UHGV-1508176_13 | Structural annotation | PF17318 | NA | NA |
| UHGV-1508176_14 | PHROG | phrog_1526 | NA | unknown function |
| UHGV-1508176_14 | eggNOG-mapper | 665950.HMPREF1025_02524 | NA | NA |
| UHGV-1508176_15 | PHROG | phrog_117 | major tail protein | tail |
| UHGV-1508176_15 | UniRef90 | UniRef90_UPI00156E6ACC | phage tail protein | NA |
| UHGV-1508176_15 | eggNOG-mapper | 1280698.AUJS01000007_gene1044 | domain, Protein | NA |
| UHGV-1508176_15 | COG | COG5492 | NA | NA |
| UHGV-1508176_15 | Structural annotation | PF04630, TIGR01603, COG5437 | NA | NA |
| UHGV-1508176_16 | PHROG | phrog_123 | tail terminator | connector |
| UHGV-1508176_16 | eggNOG-mapper | 1280698.AUJS01000007_gene1043 | NA | NA |
| UHGV-1508176_16 | Structural annotation | PF06141 | NA | NA |
| UHGV-1508176_17 | PHROG | phrog_387 | neck protein | connector |
| UHGV-1508176_17 | eggNOG-mapper | 908337.HMPREF9257_0534 | NA | NA |
| UHGV-1508176_18 | PHROG | phrog_501 | head closure Hc1 | connector |
| UHGV-1508176_18 | eggNOG-mapper | 1280698.AUJS01000007_gene1041 | NA | NA |
| UHGV-1508176_18 | Structural annotation | PF12206, COG5614 | NA | NA |
| UHGV-1508176_19 | PHROG | phrog_137 | head-tail adaptor Ad1 | connector |
| UHGV-1508176_19 | UniRef90 | UniRef90_UPI0015704514 | Gp19/Gp15/Gp42 family protein | NA |
| UHGV-1508176_19 | eggNOG-mapper | 742742.HMPREF9452_01301 | Phage protein Gp19/Gp15/Gp42 | NA |
| UHGV-1508176_19 | Pfam | PF09355 | NA | Phage_Gp19 |
| UHGV-1508176_19 | Structural annotation | PF09355 | NA | NA |
| UHGV-1508176_21 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-1508176_21 | UniRef90 | UniRef90_A0A174L023 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-1508176_21 | eggNOG-mapper | 205876.Q855V6_9CAUD | peptidase activity | NA |
| UHGV-1508176_21 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-1508176_21 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-1508176_21 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-1508176_22 | PHROG | phrog_233 | head scaffolding protein | head and packaging |
| UHGV-1508176_22 | UniRef90 | UniRef90_A0A3E4GMR3 | NA | NA |
| UHGV-1508176_22 | eggNOG-mapper | 1408304.JAHA01000007_gene1323 | NA | NA |
| UHGV-1508176_22 | Pfam | PF14265 | NA | DUF4355 |
| UHGV-1508176_22 | Structural annotation | PF14265 | NA | NA |
| UHGV-1508176_23 | PHROG | phrog_2428 | NA | unknown function |
| UHGV-1508176_23 | UniRef90 | UniRef90_A0A396QA65 | ABC transporter ATPase | NA |
| UHGV-1508176_23 | eggNOG-mapper | 632245.CLP_1645 | NA | NA |
| UHGV-1508176_23 | dbAPIS | APIS024 | Tad1 proteins are not an enzymes, but are 'sponges' that bind and sequester the immune signaling molecule (cyclic ADP-ribose or gcADPR) produced by TIR-domain proteins, thus decoupling phage sensing from immune effector activation and rendering Thoeris inactive. | NA |
| UHGV-1508176_25 | PHROG | phrog_355 | nucleoside 2-deoxyribosyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-1508176_25 | UniRef90 | UniRef90_A0A396KGT7 | NA | NA |
| UHGV-1508176_25 | eggNOG-mapper | 97138.C820_00250 | NA | NA |
| UHGV-1508176_25 | Pfam | PF14359 | NA | DUF4406 |
| UHGV-1508176_25 | Structural annotation | PF14359, COG3613 | NA | NA |
| UHGV-1508176_27 | PHROG | phrog_193 | head maturation protease | head and packaging |
| UHGV-1508176_27 | UniRef90 | UniRef90_A0A6N8H118 | CdiA_C domain-containing protein | NA |
| UHGV-1508176_27 | eggNOG-mapper | 748224.HMPREF9436_01469 | NA | NA |
| UHGV-1508176_27 | COG | COG5529 | Phage-encoded DNA-binding protein ECs1768, contains HTH and DnaT DNA-binding domains | NA |
| UHGV-1508176_28 | PHROG | phrog_104 | portal protein | head and packaging |
| UHGV-1508176_28 | UniRef90 | UniRef90_A0A174L3Q9 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1508176_28 | eggNOG-mapper | 1123263.AUKY01000112_gene2059 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1508176_28 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-1508176_28 | Structural annotation | PF05133, MF_04120, TIGR01538, COG5511 | NA | NA |
| UHGV-1508176_29 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-1508176_29 | UniRef90 | UniRef90_UPI001D0087E2 | terminase large subunit | NA |
| UHGV-1508176_29 | eggNOG-mapper | 1123263.AUKY01000112_gene2060 | phage terminase, large subunit | NA |
| UHGV-1508176_29 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-1508176_29 | Structural annotation | PF20441, PF03354, MF_04146, NF033889, COG4626 | NA | NA |
| UHGV-1508176_30 | PHROG | phrog_338 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1508176_30 | UniRef90 | UniRef90_UPI00156E0A7C | HNH endonuclease | NA |
| UHGV-1508176_30 | eggNOG-mapper | 748224.HMPREF9436_01465 | NA | NA |
| UHGV-1508176_32 | UniRef90 | UniRef90_A0A0K3A362 | Putative membrane protein | NA |
| UHGV-1508176_32 | eggNOG-mapper | 889378.Spiaf_1410 | NA | NA |
| UHGV-1508176_33 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-1508176_33 | UniRef90 | UniRef90_A0A416MN03 | Sigma70_r4 domain-containing protein | NA |
| UHGV-1508176_33 | eggNOG-mapper | 1256908.HMPREF0373_00671 | NA | NA |
| UHGV-1508176_33 | Structural annotation | PF04545, MF_00245, TIGR01636, COG2739 | NA | NA |
| UHGV-1508176_35 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-1508176_35 | UniRef90 | UniRef90_A0A396PR63 | Nucleotide pyrophosphohydrolase | NA |
| UHGV-1508176_35 | eggNOG-mapper | 765420.OSCT_3070 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-1508176_35 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-1508176_35 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-1508176_35 | Structural annotation | PF03819, MF_01020, TIGR03188, COG1694 | NA | NA |
| UHGV-1508176_39 | PHROG | phrog_3675 | NA | unknown function |
| UHGV-1508176_39 | UniRef90 | UniRef90_A0A1M6NYB4 | YjcQ protein | NA |
| UHGV-1508176_39 | eggNOG-mapper | 1507.HMPREF0262_00644 | YjcQ protein | NA |
| UHGV-1508176_39 | Pfam | PF09639 | YjcQ protein | YjcQ |
| UHGV-1508176_39 | Structural annotation | PF09639, TIGR04176, COG2345 | NA | NA |
| UHGV-1508176_40 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-1508176_40 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-1508176_40 | UniRef90 | UniRef90_A0A373MWF0 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-1508176_40 | eggNOG-mapper | 742740.HMPREF9474_04317 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-1508176_40 | PADLOC | MTase_II_00020 | Type II methyltransferase | RM |
| UHGV-1508176_40 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-1508176_40 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-1508176_40 | Structural annotation | PF00145, MF_00351, TIGR00675, COG0270 | NA | NA |
| UHGV-1508176_42 | UniRef90 | UniRef90_UPI0006C0F90C | NA | NA |
| UHGV-1508176_42 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1508176_42 | Structural annotation | PF04448, NF041588 | NA | NA |
| UHGV-1508176_43 | Structural annotation | PF20037, COG3212 | NA | NA |
| UHGV-1508176_44 | PHROG | phrog_28456 | NA | unknown function |
| UHGV-1508176_45 | PHROG | phrog_28292 | NA | unknown function |
| UHGV-1508176_45 | UniRef90 | UniRef90_A0A8B3BZ84 | 3-hydroxyacyl-CoA dehydrogenase | NA |
| UHGV-1508176_45 | eggNOG-mapper | 500632.CLONEX_01438 | NA | NA |
| UHGV-1508176_47 | UniRef90 | UniRef90_A0A1C5ULX1 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1508176_47 | eggNOG-mapper | 1232446.BAIE02000002_gene796 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-1508176_47 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1508176_47 | Structural annotation | PF13560, NF041951, COG1396 | NA | NA |
| UHGV-1508176_49 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-1508176_49 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1508176_49 | UniRef90 | UniRef90_A0A3E4LWU1 | XRE family transcriptional regulator | NA |
| UHGV-1508176_49 | eggNOG-mapper | 445972.ANACOL_03315 | NA | NA |
| UHGV-1508176_49 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1508176_49 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1508176_49 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1508176_52 | PHROG | phrog_8279 | NA | unknown function |
| UHGV-1508176_52 | UniRef90 | UniRef90_UPI00191DFC1A | NA | NA |
| UHGV-1508176_52 | eggNOG-mapper | 742723.HMPREF9477_00941 | dextransucrase activity | NA |
| UHGV-1508176_52 | Pfam | PF14020 | NA | DUF4236 |
| UHGV-1508176_52 | COG | COG3118 | Chaperedoxin CnoX, contains thioredoxin-like and TPR-like domains, YbbN/TrxSC family | NA |
| UHGV-1508176_52 | Structural annotation | PF14020, PF21602 | NA | NA |