| UHGV-0112604_1 | PHROG | phrog_2044 | RNA polymerase beta subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0112604_1 | eggNOG-mapper | 796940.HMPREF9628_00162 | NA | NA |
| UHGV-0112604_5 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0112604_5 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0112604_5 | UniRef90 | UniRef90_A0A3D0XYY2 | Cytosine-specific methyltransferase | NA |
| UHGV-0112604_5 | eggNOG-mapper | 1121871.AUAT01000002_gene1371 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-0112604_5 | PADLOC | MTase_II_00058 | Type II methyltransferase | RM |
| UHGV-0112604_5 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0112604_5 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0112604_5 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0112604_5 | Structural annotation | PF00145, MF_00786, TIGR00675, COG0270 | NA | NA |
| UHGV-0112604_8 | PHROG | phrog_8841 | DNA primase/helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0112604_8 | UniRef90 | UniRef90_UPI00143B22DC | NA | NA |
| UHGV-0112604_8 | eggNOG-mapper | 357809.Cphy_2984 | NA | NA |
| UHGV-0112604_8 | Pfam | PF06048 | NA | DUF927 |
| UHGV-0112604_8 | Pfam | PF18662 | Cch helix turn helix domain | HTH_56 |
| UHGV-0112604_8 | COG | COG5519 | NA | NA |
| UHGV-0112604_8 | Structural annotation | PF06048, PF18662, MF_00016, NF011296, COG5519 | NA | NA |
| UHGV-0112604_9 | KOfam | K02316 | dnaG; DNA primase [EC:2.7.7.101] | NA |
| UHGV-0112604_9 | PHROG | phrog_11992 | NA | unknown function |
| UHGV-0112604_9 | UniRef90 | UniRef90_UPI001D0EB8AA | CHC2 zinc finger domain-containing protein | NA |
| UHGV-0112604_9 | eggNOG-mapper | 476272.RUMHYD_01741 | CHC2 zinc finger | NA |
| UHGV-0112604_9 | PADLOC | drt-UG29 | DRT | DRT |
| UHGV-0112604_9 | Pfam | PF01807 | CHC2 zinc finger | zf-CHC2 |
| UHGV-0112604_9 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0112604_9 | Structural annotation | PF01807 | NA | NA |
| UHGV-0112604_10 | PHROG | phrog_3490 | ERCC4-type nuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0112604_10 | UniRef90 | UniRef90_A0A2K3JBB6 | ERCC4 domain-containing protein | NA |
| UHGV-0112604_10 | eggNOG-mapper | 411460.RUMTOR_02068 | NA | NA |
| UHGV-0112604_10 | Pfam | PF02732 | ERCC4 domain | ERCC4 |
| UHGV-0112604_10 | Structural annotation | PF03834, NF040956, COG1948 | NA | NA |
| UHGV-0112604_11 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0112604_11 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0112604_11 | UniRef90 | UniRef90_A0A255IMH7 | Single-stranded DNA-binding protein | NA |
| UHGV-0112604_11 | eggNOG-mapper | 397290.C810_01495 | Single-strand binding protein family | NA |
| UHGV-0112604_11 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0112604_11 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0112604_11 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0112604_11 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0112604_11 | Structural annotation | PF00436, MF_00984, NF005580, COG0629 | NA | NA |
| UHGV-0112604_12 | PHROG | phrog_3657 | NA | unknown function |
| UHGV-0112604_12 | eggNOG-mapper | 1463856.JOHY01000007_gene733 | NA | NA |
| UHGV-0112604_13 | PHROG | phrog_1499 | NA | unknown function |
| UHGV-0112604_13 | UniRef90 | UniRef90_A0A8J7H8V2 | AAA family ATPase | NA |
| UHGV-0112604_13 | eggNOG-mapper | 742733.HMPREF9469_01850 | DNA recombination | NA |
| UHGV-0112604_13 | Pfam | PF13476 | AAA domain | AAA_23 |
| UHGV-0112604_13 | COG | COG0497 | DNA repair ATPase RecN | NA |
| UHGV-0112604_13 | Structural annotation | PF11398, MF_00365, NF008121, COG0497 | NA | NA |
| UHGV-0112604_14 | KOfam | K10906 | recE; exodeoxyribonuclease VIII [EC:3.1.11.-] | NA |
| UHGV-0112604_14 | PHROG | phrog_412 | exonuclease VIII | DNA, RNA and nucleotide metabolism |
| UHGV-0112604_14 | UniRef90 | UniRef90_A0A1C6GFL6 | Exodeoxyribonuclease 8 | NA |
| UHGV-0112604_14 | eggNOG-mapper | 395494.Galf_0946 | NA | NA |
| UHGV-0112604_14 | Pfam | PF12684 | NA | DUF3799 |
| UHGV-0112604_14 | Structural annotation | PF12684, MF_03030, TIGR01896, COG2887 | NA | NA |
| UHGV-0112604_16 | PHROG | phrog_5070 | NA | unknown function |
| UHGV-0112604_16 | UniRef90 | UniRef90_C6L9Y5 | Bacterial transferase hexapeptide repeat protein | NA |
| UHGV-0112604_16 | eggNOG-mapper | 411470.RUMGNA_02189 | Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | NA |
| UHGV-0112604_16 | Pfam | PF18836 | YdcK Beta solenoid repeat | B_solenoid_ydck |
| UHGV-0112604_16 | COG | COG1044 | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase | NA |
| UHGV-0112604_20 | Structural annotation | PF11614, TIGR02588, COG2847 | NA | NA |
| UHGV-0112604_21 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0112604_21 | UniRef90 | UniRef90_A0A174D4N4 | Helix-turn-helix domain | NA |
| UHGV-0112604_21 | eggNOG-mapper | 1536772.R70723_06540 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-0112604_21 | Pfam | PF12844 | Helix-turn-helix domain | HTH_19 |
| UHGV-0112604_21 | Structural annotation | PF01381, NF041951, COG3655 | NA | NA |
| UHGV-0112604_22 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-0112604_22 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0112604_22 | UniRef90 | UniRef90_A0A7U9T541 | HTH-type transcriptional regulator Xre | NA |
| UHGV-0112604_22 | eggNOG-mapper | 1449050.JNLE01000005_gene4847 | Transcriptional | NA |
| UHGV-0112604_22 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0112604_22 | COG | COG1476 | DNA-binding transcriptional regulator, XRE-family HTH domain | NA |
| UHGV-0112604_22 | Structural annotation | PF12844, NF041951, COG1476 | NA | NA |
| UHGV-0112604_24 | KOfam | K22299 | rghR; HTH-type transcriptional regulator, competence development regulator | NA |
| UHGV-0112604_24 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0112604_24 | UniRef90 | UniRef90_A0A3R6TWB5 | XRE family transcriptional regulator | NA |
| UHGV-0112604_24 | eggNOG-mapper | 411470.RUMGNA_00189 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-0112604_24 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0112604_24 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-0112604_25 | KOfam | K03763 | polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] | NA |
| UHGV-0112604_25 | PHROG | phrog_192 | DNA polymerase exonuclease subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0112604_25 | UniRef90 | UniRef90_A0A2P1G219 | Exonuclease | NA |
| UHGV-0112604_25 | eggNOG-mapper | 938288.HG326225_gene1118 | EXOIII | NA |
| UHGV-0112604_25 | PADLOC | cd06127 | CAS-I,CAS-II,CAS-III,CAS-IV,CAS-V,CAS-VI; associated | CRISPR-CAS |
| UHGV-0112604_25 | Pfam | PF00929 | Exonuclease | RNase_T |
| UHGV-0112604_25 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-0112604_25 | NCBIFam | TIGR00573.1 | exonuclease, DNA polymerase III, epsilon subunit family | NA |
| UHGV-0112604_25 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0112604_25 | Structural annotation | PF00929, PF00533, MF_00157, NF005289, COG0847 | NA | NA |
| UHGV-0112604_26 | KOfam | K14059 | int; integrase | NA |
| UHGV-0112604_26 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0112604_26 | UniRef90 | UniRef90_A0A3D0HM31 | Site-specific integrase | NA |
| UHGV-0112604_26 | eggNOG-mapper | 1095750.HMPREF9970_1688 | Phage integrase, N-terminal SAM-like domain | NA |
| UHGV-0112604_26 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0112604_26 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0112604_26 | Structural annotation | PF00589, PF12167, MF_02055, NF040815, COG4974 | NA | NA |
| UHGV-0112604_27 | UniRef90 | UniRef90_A0A373VU48 | XRE family transcriptional regulator | NA |
| UHGV-0112604_27 | eggNOG-mapper | 140626.JHWB01000009_gene1336 | sequence-specific DNA binding | NA |
| UHGV-0112604_27 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0112604_27 | COG | COG2944 | DNA-binding transcriptional regulator YiaG, XRE-type HTH domain | NA |
| UHGV-0112604_30 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0112604_30 | PHROG | phrog_1794 | amidase | lysis |
| UHGV-0112604_30 | UniRef90 | UniRef90_UPI000F0450D1 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0112604_30 | eggNOG-mapper | 1203606.HMPREF1526_00589 | Ami_2 | NA |
| UHGV-0112604_30 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0112604_30 | COG | COG5632 | N-acetylmuramoyl-L-alanine amidase CwlA | NA |
| UHGV-0112604_30 | Structural annotation | PF01510, MF_04111, NF008758, COG5632 | NA | NA |
| UHGV-0112604_31 | PHROG | phrog_443 | holin | lysis |
| UHGV-0112604_31 | UniRef90 | UniRef90_UPI001D060615 | holin | NA |
| UHGV-0112604_31 | eggNOG-mapper | 411463.EUBVEN_02210 | Putative lactococcus lactis phage r1t holin | NA |
| UHGV-0112604_31 | Pfam | PF16945 | Putative lactococcus lactis phage r1t holin | Phage_r1t_holin |
| UHGV-0112604_31 | Structural annotation | PF16945 | NA | NA |
| UHGV-0112604_32 | PHROG | phrog_4105 | NA | unknown function |
| UHGV-0112604_32 | eggNOG-mapper | 657322.FPR_27220 | NA | NA |
| UHGV-0112604_34 | UniRef90 | UniRef90_UPI00164C2D72 | leucine-rich repeat domain-containing protein | NA |
| UHGV-0112604_34 | Pfam | PF13306 | BspA type Leucine rich repeat region (6 copies) | LRR_5 |
| UHGV-0112604_35 | PHROG | phrog_24103 | NA | unknown function |
| UHGV-0112604_37 | PHROG | phrog_3558 | tail protein | tail |
| UHGV-0112604_37 | UniRef90 | UniRef90_A0A386PHP6 | Lysin | NA |
| UHGV-0112604_37 | eggNOG-mapper | 641112.ACOK01000073_gene2906 | Prophage endopeptidase tail | NA |
| UHGV-0112604_37 | Pfam | PF06605 | Prophage endopeptidase tail | Prophage_tail |
| UHGV-0112604_37 | COG | COG4926 | Phage-related protein | NA |
| UHGV-0112604_37 | Structural annotation | PF14594, TIGR01665, COG4379 | NA | NA |
| UHGV-0112604_38 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0112604_38 | eggNOG-mapper | 1414720.CBYM010000001_gene708 | PFAM Phage tail protein | NA |
| UHGV-0112604_38 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0112604_38 | Structural annotation | PF20195, PF21621, TIGR01633, COG4722 | NA | NA |
| UHGV-0112604_39 | PHROG | phrog_991 | tail length tape measure protein | tail |
| UHGV-0112604_39 | UniRef90 | UniRef90_UPI00189AF390 | phage tail tape measure protein | NA |
| UHGV-0112604_39 | eggNOG-mapper | 931626.Awo_c30950 | Phage tail tape measure protein, TP901 family | NA |
| UHGV-0112604_39 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0112604_39 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0112604_39 | COG | COG0739 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain | NA |
| UHGV-0112604_39 | Structural annotation | PF10145, TIGR01760, COG5280 | NA | NA |
| UHGV-0112604_40 | PHROG | phrog_5802 | NA | unknown function |
| UHGV-0112604_42 | UniRef90 | UniRef90_A0A316S919 | Phage tail protein | NA |
| UHGV-0112604_42 | eggNOG-mapper | 1384484.AEQU_1175 | NA | NA |
| UHGV-0112604_42 | Structural annotation | PF04630, TIGR01603, COG5437 | NA | NA |
| UHGV-0112604_43 | PHROG | phrog_5509 | neck protein | connector |
| UHGV-0112604_43 | UniRef90 | UniRef90_W0FMR6 | Gp9 protein | NA |
| UHGV-0112604_43 | eggNOG-mapper | 1347392.CCEZ01000045_gene11 | NA | NA |
| UHGV-0112604_43 | Structural annotation | TIGR01725, COG5005 | NA | NA |
| UHGV-0112604_44 | eggNOG-mapper | 1121866.AUGK01000006_gene883 | NA | NA |
| UHGV-0112604_44 | Structural annotation | PF05657, COG3167 | NA | NA |
| UHGV-0112604_45 | PHROG | phrog_5635 | head-tail adaptor | connector |
| UHGV-0112604_45 | eggNOG-mapper | 1121866.AUGK01000006_gene882 | NA | NA |
| UHGV-0112604_45 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-0112604_46 | PHROG | phrog_749 | NA | unknown function |
| UHGV-0112604_46 | UniRef90 | UniRef90_A0A1I3QJG6 | Phage gp6-like head-tail connector protein | NA |
| UHGV-0112604_46 | eggNOG-mapper | 349161.Dred_2603 | NA | NA |
| UHGV-0112604_47 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0112604_47 | UniRef90 | UniRef90_A0A316SAG0 | Phage major capsid protein | NA |
| UHGV-0112604_47 | eggNOG-mapper | 1384484.AEQU_1180 | Phage capsid family | NA |
| UHGV-0112604_47 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0112604_47 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0112604_47 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0112604_47 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0112604_48 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-0112604_48 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-0112604_48 | UniRef90 | UniRef90_A0A7C6S6U4 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-0112604_48 | eggNOG-mapper | 1232452.BAIB02000007_gene1626 | Belongs to the peptidase S14 family | NA |
| UHGV-0112604_48 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-0112604_48 | COG | COG0740 | ATP-dependent protease ClpP, protease subunit | NA |
| UHGV-0112604_48 | Structural annotation | PF00574, MF_00444, TIGR00493, COG0740 | NA | NA |
| UHGV-0112604_49 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-0112604_49 | UniRef90 | UniRef90_UPI00148519DF | phage portal protein | NA |
| UHGV-0112604_49 | eggNOG-mapper | 1307436.PBF_22063 | Phage portal protein | NA |
| UHGV-0112604_49 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-0112604_49 | NCBIFam | TIGR01537.1 | phage portal protein | NA |
| UHGV-0112604_49 | COG | COG4695 | Phage portal protein BeeE | NA |
| UHGV-0112604_49 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0112604_50 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-0112604_50 | UniRef90 | UniRef90_UPI00164CCF79 | terminase large subunit | NA |
| UHGV-0112604_50 | eggNOG-mapper | 1235798.C817_02581 | Phage terminase-like protein large subunit | NA |
| UHGV-0112604_50 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-0112604_50 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-0112604_50 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-0112604_50 | Structural annotation | PF20441, PF03354, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0112604_52 | KOfam | K07451 | mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] | NA |
| UHGV-0112604_52 | PHROG | phrog_119 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0112604_52 | UniRef90 | UniRef90_A0A415MTD9 | HNH endonuclease | NA |
| UHGV-0112604_52 | eggNOG-mapper | 610130.Closa_0739 | HNH nucleases | NA |
| UHGV-0112604_52 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0112604_52 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0112604_53 | eggNOG-mapper | 537013.CLOSTMETH_01096 | NA | NA |
| UHGV-0112604_54 | KOfam | K18843 | hicB; antitoxin HicB | NA |
| UHGV-0112604_54 | PHROG | phrog_497 | toxin-antitoxin system HicB-like | moron, auxiliary metabolic gene and host takeover |
| UHGV-0112604_54 | UniRef90 | UniRef90_A0A7X7APK8 | HicB family protein | NA |
| UHGV-0112604_54 | eggNOG-mapper | 1122925.KB895394_gene1703 | HicB_like antitoxin of bacterial toxin-antitoxin system | NA |
| UHGV-0112604_54 | Pfam | PF15919 | HicB_like antitoxin of bacterial toxin-antitoxin system | HicB_lk_antitox |
| UHGV-0112604_54 | COG | COG1598 | Antitoxin component HicB of the HicAB toxin-antitoxin system | NA |
| UHGV-0112604_54 | Structural annotation | PF15919, COG1598 | NA | NA |
| UHGV-0112604_55 | KOfam | K07339 | hicA; mRNA interferase HicA [EC:3.1.-.-] | NA |
| UHGV-0112604_55 | PHROG | phrog_353 | toxin | moron, auxiliary metabolic gene and host takeover |
| UHGV-0112604_55 | UniRef90 | UniRef90_C7H0H9 | YcfA-like protein | NA |
| UHGV-0112604_55 | eggNOG-mapper | 397290.C810_01568 | HicA toxin of bacterial toxin-antitoxin, | NA |
| UHGV-0112604_55 | Pfam | PF07927 | HicA toxin of bacterial toxin-antitoxin, | HicA_toxin |
| UHGV-0112604_55 | Structural annotation | PF07927 | NA | NA |
| UHGV-0112604_57 | PHROG | phrog_918 | NA | unknown function |
| UHGV-0112604_57 | UniRef90 | UniRef90_UPI001C015439 | NA | NA |
| UHGV-0112604_57 | eggNOG-mapper | 1158614.I592_01104 | NA | NA |
| UHGV-0112604_57 | Pfam | PF19791 | NA | DUF6275 |
| UHGV-0112604_57 | Structural annotation | PF19791 | NA | NA |