| UHGV-0015322_1 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0015322_1 | UniRef90 | UniRef90_A0A3N0HYK4 | Endonuclease | NA |
| UHGV-0015322_1 | eggNOG-mapper | 857293.CAAU_0780 | YqaJ-like viral recombinase domain | NA |
| UHGV-0015322_1 | Pfam | PF09588 | YqaJ-like viral recombinase domain | YqaJ |
| UHGV-0015322_1 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-0015322_1 | Structural annotation | PF09588, MF_03030, TIGR03033, COG5377 | NA | NA |
| UHGV-0015322_2 | KOfam | K07455 | recT; recombination protein RecT | NA |
| UHGV-0015322_2 | PHROG | phrog_148 | RecT-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0015322_2 | UniRef90 | UniRef90_UPI0014317E61 | recombinase RecT | NA |
| UHGV-0015322_2 | eggNOG-mapper | 1226322.HMPREF1545_00015 | RecT family | NA |
| UHGV-0015322_2 | Pfam | PF03837 | RecT family | RecT |
| UHGV-0015322_2 | NCBIFam | TIGR00616.1 | recombinase, phage RecT family | NA |
| UHGV-0015322_2 | COG | COG3723 | Recombinational DNA repair protein RecT | NA |
| UHGV-0015322_2 | Structural annotation | PF03837, NF007351, COG3723 | NA | NA |
| UHGV-0015322_3 | PHROG | phrog_186 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0015322_3 | UniRef90 | UniRef90_UPI001C395B09 | winged helix-turn-helix transcriptional regulator | NA |
| UHGV-0015322_3 | Pfam | PF13412 | Winged helix-turn-helix DNA-binding | HTH_24 |
| UHGV-0015322_3 | Structural annotation | PF09681, NF033788, COG0640 | NA | NA |
| UHGV-0015322_4 | AcrCatalog | cluster_100602 | NA | NA |
| UHGV-0015322_5 | Structural annotation | PF10771, MF_01819, NF040642, COG1846 | NA | NA |
| UHGV-0015322_7 | PHROG | phrog_4074 | NA | unknown function |
| UHGV-0015322_8 | PHROG | phrog_6072 | NA | unknown function |
| UHGV-0015322_9 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0015322_9 | UniRef90 | UniRef90_E2NU95 | HNHc domain-containing protein | NA |
| UHGV-0015322_9 | eggNOG-mapper | 1410650.JHWL01000037_gene604 | NA | NA |
| UHGV-0015322_9 | Pfam | PF13392 | HNH endonuclease | HNH_3 |
| UHGV-0015322_9 | Structural annotation | PF13392 | NA | NA |
| UHGV-0015322_10 | PHROG | phrog_5696 | NA | unknown function |
| UHGV-0015322_10 | UniRef90 | UniRef90_E2NU94 | N6_Mtase domain-containing protein | NA |
| UHGV-0015322_10 | eggNOG-mapper | 1123504.JQKD01000088_gene782 | N-6 DNA Methylase | NA |
| UHGV-0015322_10 | Pfam | PF02384 | N-6 DNA Methylase | N6_Mtase |
| UHGV-0015322_10 | COG | COG0286 | Type I restriction-modification system, DNA methylase subunit | NA |
| UHGV-0015322_10 | Structural annotation | PF13679, MF_02126, TIGR00497, COG0286 | NA | NA |
| UHGV-0015322_11 | KOfam | K03733 | xerC; integrase/recombinase XerC | NA |
| UHGV-0015322_11 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0015322_11 | UniRef90 | UniRef90_E2NU93 | Site-specific recombinase, phage integrase family | NA |
| UHGV-0015322_11 | eggNOG-mapper | 411460.RUMTOR_01870 | Phage integrase, N-terminal SAM-like domain | NA |
| UHGV-0015322_11 | Pfam | PF13495 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_4 |
| UHGV-0015322_11 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0015322_11 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-0015322_11 | Structural annotation | PF00589, PF02899, MF_01807, TIGR02224, COG4973 | NA | NA |
| UHGV-0015322_12 | PHROG | phrog_4019 | NA | unknown function |
| UHGV-0015322_12 | UniRef90 | UniRef90_F9PY75 | Conserved domain protein | NA |
| UHGV-0015322_13 | PHROG | phrog_22292 | NA | unknown function |
| UHGV-0015322_17 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0015322_17 | Pfam | PF07374 | NA | DUF1492 |
| UHGV-0015322_17 | COG | COG1191 | DNA-directed RNA polymerase specialized sigma subunit | NA |
| UHGV-0015322_18 | PHROG | phrog_30609 | NA | unknown function |
| UHGV-0015322_18 | Structural annotation | PF21485 | NA | NA |
| UHGV-0015322_19 | KOfam | K07451 | mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] | NA |
| UHGV-0015322_19 | PHROG | phrog_4581 | terminase small subunit | head and packaging |
| UHGV-0015322_19 | UniRef90 | UniRef90_A0A0J8Z1U8 | Prophage LambdaBa04, Gp54 | NA |
| UHGV-0015322_19 | eggNOG-mapper | 1414720.CBYM010000040_gene1642 | HNH nucleases | NA |
| UHGV-0015322_19 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0015322_19 | Pfam | PF13671 | AAA domain | AAA_33 |
| UHGV-0015322_19 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0015322_19 | Structural annotation | PF13671, MF_03171, NF005251, NF008448, COG4639 | NA | NA |
| UHGV-0015322_20 | PHROG | phrog_1066 | NA | unknown function |
| UHGV-0015322_20 | eggNOG-mapper | 1094508.Tsac_2428 | NA | NA |
| UHGV-0015322_20 | Structural annotation | PF05119, TIGR01558, COG3747 | NA | NA |
| UHGV-0015322_21 | PHROG | phrog_9 | terminase large subunit | head and packaging |
| UHGV-0015322_21 | UniRef90 | UniRef90_A0A0J8Z1B0 | Phage terminase | NA |
| UHGV-0015322_21 | eggNOG-mapper | 1444310.JANV01000004_gene2684 | Terminase | NA |
| UHGV-0015322_21 | Pfam | PF03354 | Terminase large subunit, ATPase domain | TerL_ATPase |
| UHGV-0015322_21 | Pfam | PF20441 | Terminase large subunit, endonuclease domain | TerL_nuclease |
| UHGV-0015322_21 | COG | COG4626 | Phage terminase-like protein, large subunit, contains N-terminal HTH domain | NA |
| UHGV-0015322_21 | Structural annotation | PF20441, PF03354, MF_04145, TIGR01547, COG4626 | NA | NA |
| UHGV-0015322_22 | PHROG | phrog_12 | portal protein | head and packaging |
| UHGV-0015322_22 | UniRef90 | UniRef90_A0A0J8Z114 | Prophage LambdaBa04, portal protein | NA |
| UHGV-0015322_22 | eggNOG-mapper | 1414720.CBYM010000040_gene1645 | Portal protein | NA |
| UHGV-0015322_22 | Pfam | PF04860 | Phage portal protein | Phage_portal |
| UHGV-0015322_22 | COG | COG0241 | Histidinol phosphatase/D-glycero-mannoheptose bisphosphatephosphatase, HAD superfamily | NA |
| UHGV-0015322_22 | Structural annotation | PF04860, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0015322_23 | KOfam | K01358 | clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] | NA |
| UHGV-0015322_23 | PHROG | phrog_94 | head maturation protease | head and packaging |
| UHGV-0015322_23 | UniRef90 | UniRef90_A0A0J8Z1U4 | ATP-dependent Clp protease proteolytic subunit | NA |
| UHGV-0015322_23 | eggNOG-mapper | 396359.Q0SPK3_9CAUD | Clp protease | NA |
| UHGV-0015322_23 | Pfam | PF00574 | Clp protease | CLP_protease |
| UHGV-0015322_23 | Structural annotation | PF00574, MF_00444, NF011091, COG0740 | NA | NA |
| UHGV-0015322_24 | PHROG | phrog_10 | major head protein | head and packaging |
| UHGV-0015322_24 | UniRef90 | UniRef90_A0A318LDM5 | HK97 family phage major capsid protein | NA |
| UHGV-0015322_24 | eggNOG-mapper | 1414720.CBYM010000040_gene1647 | Phage capsid family | NA |
| UHGV-0015322_24 | Pfam | PF05065 | Phage capsid family | Phage_capsid |
| UHGV-0015322_24 | NCBIFam | TIGR01554.2 | phage major capsid protein | NA |
| UHGV-0015322_24 | COG | COG4653 | Predicted phage phi-C31 gp36 major capsid-like protein | NA |
| UHGV-0015322_24 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0015322_25 | PHROG | phrog_5223 | neck protein | connector |
| UHGV-0015322_25 | UniRef90 | UniRef90_A0A235B1E7 | DNA-packaging protein | NA |
| UHGV-0015322_25 | eggNOG-mapper | 1094508.Tsac_2423 | NA | NA |
| UHGV-0015322_26 | PHROG | phrog_1951 | head-tail adaptor | connector |
| UHGV-0015322_26 | UniRef90 | UniRef90_A0A0J9BRH9 | Phage head-tail adaptor | NA |
| UHGV-0015322_26 | eggNOG-mapper | 768704.Desmer_4460 | head-tail adaptor | NA |
| UHGV-0015322_26 | NCBIFam | TIGR01563.1 | phage head closure protein | NA |
| UHGV-0015322_26 | COG | COG5614 | Phage head-tail adaptor | NA |
| UHGV-0015322_26 | Structural annotation | PF05521, TIGR01563, COG5614 | NA | NA |
| UHGV-0015322_27 | UniRef90 | UniRef90_A0A0J8Z1A5 | Phage protein, HK97 gp10 family | NA |
| UHGV-0015322_27 | eggNOG-mapper | 1414720.CBYM010000040_gene1650 | NA | NA |
| UHGV-0015322_27 | Structural annotation | TIGR01725 | NA | NA |
| UHGV-0015322_28 | PHROG | phrog_957 | head protein | head and packaging |
| UHGV-0015322_28 | UniRef90 | UniRef90_UPI001C0F6033 | NA | NA |
| UHGV-0015322_28 | eggNOG-mapper | 1414720.CBYM010000040_gene1651 | NA | NA |
| UHGV-0015322_28 | Structural annotation | PF11367, COG4722 | NA | NA |
| UHGV-0015322_29 | PHROG | phrog_885 | major tail protein | tail |
| UHGV-0015322_29 | eggNOG-mapper | 1414720.CBYM010000040_gene1652 | NA | NA |
| UHGV-0015322_29 | Structural annotation | PF09393, TIGR01603, COG3498 | NA | NA |
| UHGV-0015322_30 | eggNOG-mapper | 457396.CSBG_01055 | NA | NA |
| UHGV-0015322_31 | eggNOG-mapper | 457396.CSBG_01056 | NA | NA |
| UHGV-0015322_32 | PHROG | phrog_17020 | NA | unknown function |
| UHGV-0015322_32 | UniRef90 | UniRef90_A0A0J8Z1A0 | Tail protein | NA |
| UHGV-0015322_32 | eggNOG-mapper | 1122989.KB898607_gene43 | nuclear chromosome segregation | NA |
| UHGV-0015322_32 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0015322_33 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0015322_33 | UniRef90 | UniRef90_UPI00156E3DDD | phage tail protein | NA |
| UHGV-0015322_33 | eggNOG-mapper | 1256908.HMPREF0373_00467 | NA | NA |
| UHGV-0015322_33 | Structural annotation | PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-0015322_34 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-0015322_34 | UniRef90 | UniRef90_A0A1M6B1Q8 | Virus ReqiPepy6 Gp37-like protein | NA |
| UHGV-0015322_34 | eggNOG-mapper | 1232446.BAIE02000011_gene1584 | NA | NA |
| UHGV-0015322_34 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-0015322_34 | Structural annotation | PF14594, TIGR01665, COG4379 | NA | NA |
| UHGV-0015322_35 | PHROG | phrog_9994 | NA | unknown function |
| UHGV-0015322_35 | eggNOG-mapper | 1232446.BAIE02000011_gene1583 | NA | NA |
| UHGV-0015322_35 | Structural annotation | PF08931, PF20747 | NA | NA |
| UHGV-0015322_36 | KOfam | K10421 | CLIP1, RSN; CAP-Gly domain-containing linker protein 1 | NA |
| UHGV-0015322_36 | PHROG | phrog_17147 | NA | unknown function |
| UHGV-0015322_36 | eggNOG-mapper | 478749.BRYFOR_08557 | NA | NA |
| UHGV-0015322_36 | Structural annotation | PF16323 | NA | NA |
| UHGV-0015322_37 | KOfam | K00986 | ltrA; RNA-directed DNA polymerase [EC:2.7.7.49] | NA |
| UHGV-0015322_37 | PHROG | phrog_1423 | Reverse transcriptase | DNA, RNA and nucleotide metabolism |
| UHGV-0015322_37 | UniRef90 | UniRef90_A0A396PAA8 | Reverse transcriptase domain-containing protein | NA |
| UHGV-0015322_37 | eggNOG-mapper | 478749.BRYFOR_08556 | Reverse transcriptase (RNA-dependent DNA polymerase) | NA |
| UHGV-0015322_37 | PADLOC | icity0040 | RT (reverse transcriptase) | CRISPR-CAS |
| UHGV-0015322_37 | Pfam | PF00078 | Reverse transcriptase (RNA-dependent DNA polymerase) | RVT_1 |
| UHGV-0015322_37 | COG | COG3344 | Retron-type reverse transcriptase | NA |
| UHGV-0015322_37 | Structural annotation | PF00078, MF_04065, TIGR04416, COG3344 | NA | NA |
| UHGV-0015322_39 | NCBIFam | NF040910.1 | CD1375 family protein | NA |
| UHGV-0015322_39 | Structural annotation | NF040910 | NA | NA |
| UHGV-0015322_40 | PHROG | phrog_199 | holin | lysis |
| UHGV-0015322_40 | UniRef90 | UniRef90_E2NRB7 | Toxin secretion/phage lysis holin | NA |
| UHGV-0015322_40 | eggNOG-mapper | 742723.HMPREF9477_00889 | Bacteriophage holin family | NA |
| UHGV-0015322_40 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0015322_40 | NCBIFam | TIGR01593.1 | toxin secretion/phage lysis holin | NA |
| UHGV-0015322_40 | COG | COG4824 | Phage-related holin (Lysis protein) | NA |
| UHGV-0015322_40 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-0015322_41 | PHROG | phrog_774 | NA | unknown function |
| UHGV-0015322_41 | eggNOG-mapper | 397290.C810_05225 | NA | NA |
| UHGV-0015322_42 | KOfam | K01448 | amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0015322_42 | PHROG | phrog_435 | endolysin | lysis |
| UHGV-0015322_42 | UniRef90 | UniRef90_B0G4K0 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0015322_42 | eggNOG-mapper | 411461.DORFOR_01187 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0015322_42 | Pfam | PF01520 | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
| UHGV-0015322_42 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0015322_42 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0015322_42 | Structural annotation | PF01520, PF01471, MF_00562, TIGR02883, NF038080, COG0860, COG3409 | NA | NA |
| UHGV-0015322_43 | eggNOG-mapper | 1504823.CCMM01000008_gene725 | NA | NA |
| UHGV-0015322_43 | Structural annotation | PF09274, COG4710 | NA | NA |
| UHGV-0015322_45 | KOfam | K07171 | mazF, ndoA, chpA; mRNA interferase MazF [EC:3.1.-.-] | NA |
| UHGV-0015322_45 | PHROG | phrog_1412 | antitoxin mazE-like | moron, auxiliary metabolic gene and host takeover |
| UHGV-0015322_45 | UniRef90 | UniRef90_A0A374RSU2 | Type II toxin-antitoxin system PemK/MazF family toxin | NA |
| UHGV-0015322_45 | eggNOG-mapper | 1225806.J7KDP1_9CAUD | Pfam:PemK_toxin | NA |
| UHGV-0015322_45 | Pfam | PF02452 | PemK-like, MazF-like toxin of type II toxin-antitoxin system | PemK_toxin |
| UHGV-0015322_46 | KOfam | K01356 | lexA; repressor LexA [EC:3.4.21.88] | NA |
| UHGV-0015322_46 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0015322_46 | UniRef90 | UniRef90_A0A1Y4R5X5 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0015322_46 | eggNOG-mapper | 476272.RUMHYD_03305 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-0015322_46 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0015322_46 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-0015322_46 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0015322_46 | Structural annotation | PF00717, PF01381, MF_00015, TIGR00498, COG1974 | NA | NA |
| UHGV-0015322_47 | KOfam | K07729 | K07729; putative transcriptional regulator | NA |
| UHGV-0015322_47 | PHROG | phrog_6499 | transcriptional regulator | transcription regulation |
| UHGV-0015322_47 | UniRef90 | UniRef90_A0A413S067 | XRE family transcriptional regulator | NA |
| UHGV-0015322_47 | eggNOG-mapper | 1256908.HMPREF0373_00646 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0015322_47 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0015322_47 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0015322_47 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0015322_47 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0015322_48 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0015322_48 | PHROG | phrog_63 | anti-repressor Ant | transcription regulation |
| UHGV-0015322_48 | UniRef90 | UniRef90_UPI00067F3EAD | phage antirepressor KilAC domain-containing protein | NA |
| UHGV-0015322_48 | eggNOG-mapper | 1499683.CCFF01000017_gene2614 | Phage antirepressor protein | NA |
| UHGV-0015322_48 | Pfam | PF08346 | AntA/AntB antirepressor | AntA |
| UHGV-0015322_48 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0015322_48 | COG | COG3561 | Phage anti-repressor protein Ant | NA |
| UHGV-0015322_48 | Structural annotation | PF03374, PF08346, TIGR02681, COG3645, COG3561 | NA | NA |
| UHGV-0015322_49 | UniRef90 | UniRef90_A0A415XFB8 | DNA-binding protein | NA |
| UHGV-0015322_49 | Structural annotation | PF12728, TIGR01764, COG3311 | NA | NA |
| UHGV-0015322_54 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0015322_54 | UniRef90 | UniRef90_A0A4U4E400 | Endonuclease (Fragment) | NA |
| UHGV-0015322_54 | eggNOG-mapper | 1158601.I585_00722 | YqaJ-like viral recombinase domain | NA |
| UHGV-0015322_54 | Pfam | PF09588 | YqaJ-like viral recombinase domain | YqaJ |
| UHGV-0015322_54 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |