| UHGV-0019649_3 | KOfam | K03465 | thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148] | NA |
| UHGV-0019649_3 | PHROG | phrog_85 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0019649_3 | UniRef90 | UniRef90_A0A523UB32 | Flavin-dependent thymidylate synthase | NA |
| UHGV-0019649_3 | eggNOG-mapper | 525904.Tter_0028 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant | NA |
| UHGV-0019649_3 | Pfam | PF02511 | Thymidylate synthase complementing protein | Thy1 |
| UHGV-0019649_3 | NCBIFam | TIGR02170.1 | FAD-dependent thymidylate synthase | NA |
| UHGV-0019649_3 | COG | COG1351 | Thymidylate synthase ThyX, FAD-dependent family | NA |
| UHGV-0019649_3 | Structural annotation | PF02511, MF_01408, TIGR02170, COG1351 | NA | NA |
| UHGV-0019649_6 | PHROG | phrog_236 | nucleotide kinase | other |
| UHGV-0019649_6 | UniRef90 | UniRef90_A8ATS6 | Gp38 | NA |
| UHGV-0019649_6 | eggNOG-mapper | 665950.HMPREF1025_01364 | NA | NA |
| UHGV-0019649_6 | Pfam | PF11753 | NA | DUF3310 |
| UHGV-0019649_11 | UniRef90 | UniRef90_UPI001490D16B | VRR-NUC domain-containing protein | NA |
| UHGV-0019649_11 | eggNOG-mapper | 1430331.EP10_02390 | Archaeal holliday junction resolvase (hjc) | NA |
| UHGV-0019649_11 | COG | COG1591 | Holliday junction resolvase Hjc, archaeal type | NA |
| UHGV-0019649_12 | PHROG | phrog_1909 | NA | unknown function |
| UHGV-0019649_12 | eggNOG-mapper | 1169161.KB897713_gene6953 | NA | NA |
| UHGV-0019649_12 | Structural annotation | TIGR01651, COG4547 | NA | NA |
| UHGV-0019649_13 | KOfam | K09882 | cobS; cobaltochelatase CobS [EC:6.6.1.2] | NA |
| UHGV-0019649_13 | PHROG | phrog_249 | porphyrin biosynthesis | moron, auxiliary metabolic gene and host takeover |
| UHGV-0019649_13 | UniRef90 | UniRef90_A0A3D2MTC6 | AAA domain-containing protein | NA |
| UHGV-0019649_13 | eggNOG-mapper | 1173745.A0A059TAP4_9CAUD | AAA domain (dynein-related subfamily) | NA |
| UHGV-0019649_13 | Pfam | PF07728 | AAA domain (dynein-related subfamily) | AAA_5 |
| UHGV-0019649_15 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0019649_15 | eggNOG-mapper | 1203554.HMPREF1476_00223 | YqaJ-like viral recombinase domain | NA |
| UHGV-0019649_15 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-0019649_15 | Structural annotation | PF09588, TIGR03033, COG5377 | NA | NA |
| UHGV-0019649_16 | eggNOG-mapper | 888060.HMPREF9081_0430 | ERF superfamily | NA |
| UHGV-0019649_17 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-0019649_17 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0019649_17 | UniRef90 | UniRef90_A0A843DY29 | DEAD/DEAH box helicase | NA |
| UHGV-0019649_17 | eggNOG-mapper | 1219626.HMPREF1639_07295 | SNF2 family N-terminal domain | NA |
| UHGV-0019649_17 | PADLOC | ZorD1_00007 | SWI2/SNF2 helicase, Mrr-like nuclease | Zorya |
| UHGV-0019649_17 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-0019649_17 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-0019649_17 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-0019649_17 | Structural annotation | PF00176, PF00271, MF_01821, NF041790, COG0553 | NA | NA |
| UHGV-0019649_18 | PHROG | phrog_864 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-0019649_18 | UniRef90 | UniRef90_A0A511H142 | SF3 helicase domain-containing protein | NA |
| UHGV-0019649_18 | eggNOG-mapper | 1382304.JNIL01000001_gene3514 | Phage plasmid primase, P4 | NA |
| UHGV-0019649_18 | Pfam | PF08706 | D5 N terminal like | D5_N |
| UHGV-0019649_18 | Pfam | PF19263 | NA | DUF5906 |
| UHGV-0019649_18 | COG | COG3378 | DNA primase, phage- or plasmid-associated | NA |
| UHGV-0019649_19 | Pfam | PF09479 | Listeria-Bacteroides repeat domain (List_Bact_rpt) | Flg_new |
| UHGV-0019649_19 | NCBIFam | TIGR02543.1 | TIGR02543 family repeat protein | NA |
| UHGV-0019649_21 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0019649_21 | UniRef90 | UniRef90_A0A7M1S0F9 | Spike protein/glycoprotein | NA |
| UHGV-0019649_21 | eggNOG-mapper | 762968.HMPREF9441_00555 | NA | NA |
| UHGV-0019649_25 | PHROG | phrog_863 | tail fiber assembly | tail |
| UHGV-0019649_26 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-0019649_26 | UniRef90 | UniRef90_A0A5D0JNY7 | NA | NA |
| UHGV-0019649_26 | eggNOG-mapper | 202954.BBNK01000010_gene1458 | NA | NA |
| UHGV-0019649_26 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-0019649_26 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-0019649_26 | Structural annotation | PF11195 | NA | NA |
| UHGV-0019649_29 | PHROG | phrog_1589 | NA | unknown function |
| UHGV-0019649_29 | eggNOG-mapper | 5722.XP_001317274.1 | protein kinase A regulatory subunit binding | NA |
| UHGV-0019649_29 | Pfam | PF12810 | Glycine rich protein | Gly_rich |
| UHGV-0019649_30 | eggNOG-mapper | 1280698.AUJS01000007_gene1056 | NA | NA |
| UHGV-0019649_30 | Structural annotation | PF07703, TIGR02657, COG2372 | NA | NA |
| UHGV-0019649_31 | Pfam | PF13754 | NA | Big_3_4 |
| UHGV-0019649_32 | KOfam | K13276 | bpr; bacillopeptidase F [EC:3.4.21.-] | NA |
| UHGV-0019649_32 | PHROG | phrog_11157 | NA | unknown function |
| UHGV-0019649_32 | UniRef90 | UniRef90_A0A174LMA6 | Bacillopeptidase F | NA |
| UHGV-0019649_32 | eggNOG-mapper | 476272.RUMHYD_02867 | NA | NA |
| UHGV-0019649_32 | Pfam | PF19077 | Bacterial Ig-like domain | Big_13 |
| UHGV-0019649_32 | Pfam | PF09136 | Glucodextranase, domain B | Glucodextran_B |
| UHGV-0019649_32 | COG | COG3292 | Periplasmic ligand-binding sensor domain | NA |
| UHGV-0019649_32 | Structural annotation | PF09136, PF13205, PF13754, MF_04116, NF032891, COG2372, COG5456 | NA | NA |
| UHGV-0019649_33 | PHROG | phrog_13879 | NA | unknown function |
| UHGV-0019649_34 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-0019649_34 | eggNOG-mapper | 324057.Pjdr2_1553 | NA | NA |
| UHGV-0019649_35 | PHROG | phrog_58 | tail length tape measure protein | tail |
| UHGV-0019649_35 | eggNOG-mapper | 1232449.BAHV02000010_gene2723 | domain protein | NA |
| UHGV-0019649_35 | COG | COG1511 | NA | NA |
| UHGV-0019649_38 | eggNOG-mapper | 445971.ANASTE_00155 | regulation of response to stimulus | NA |
| UHGV-0019649_38 | Pfam | PF09479 | Listeria-Bacteroides repeat domain (List_Bact_rpt) | Flg_new |
| UHGV-0019649_38 | COG | COG4886 | Leucine-rich repeat (LRR) protein | NA |
| UHGV-0019649_40 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-0019649_40 | UniRef90 | UniRef90_A0A7X5KS36 | HK97 gp10 family phage protein | NA |
| UHGV-0019649_40 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-0019649_40 | NCBIFam | TIGR01725.1 | HK97-gp10 family putative phage morphogenesis protein | NA |
| UHGV-0019649_40 | Structural annotation | PF20039, TIGR01725, COG5005 | NA | NA |
| UHGV-0019649_42 | Structural annotation | TIGR01560 | NA | NA |
| UHGV-0019649_46 | PHROG | phrog_422 | major head protein | head and packaging |
| UHGV-0019649_46 | UniRef90 | UniRef90_G4D5H4 | Lj928 prophage protein | NA |
| UHGV-0019649_46 | eggNOG-mapper | 768710.DesyoDRAFT_3140 | NA | NA |
| UHGV-0019649_46 | Structural annotation | PF05065, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-0019649_47 | PHROG | phrog_172 | head scaffolding protein | head and packaging |
| UHGV-0019649_47 | Pfam | PF14265 | NA | DUF4355 |
| UHGV-0019649_48 | PHROG | phrog_2841 | minor head protein | head and packaging |
| UHGV-0019649_48 | UniRef90 | UniRef90_UPI001C11FEDD | minor capsid protein | NA |
| UHGV-0019649_48 | eggNOG-mapper | 1294142.CINTURNW_1685 | Phage Mu protein F like protein | NA |
| UHGV-0019649_48 | Pfam | PF04233 | Phage Mu protein F like protein | Phage_Mu_F |
| UHGV-0019649_48 | NCBIFam | TIGR01641.1 | minor capsid protein | NA |
| UHGV-0019649_48 | COG | COG2369 | NA | NA |
| UHGV-0019649_48 | Structural annotation | PF04233, TIGR01641, COG2369 | NA | NA |
| UHGV-0019649_49 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-0019649_49 | UniRef90 | UniRef90_A0A843IEY6 | Phage portal protein | NA |
| UHGV-0019649_49 | eggNOG-mapper | 1121947.AUHK01000002_gene930 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-0019649_49 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-0019649_49 | NCBIFam | TIGR01538.1 | phage portal protein | NA |
| UHGV-0019649_49 | Structural annotation | PF05133, MF_04120, TIGR01538, COG3567 | NA | NA |
| UHGV-0019649_50 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0019649_50 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-0019649_50 | UniRef90 | UniRef90_A0A843DZZ3 | Terminase family protein | NA |
| UHGV-0019649_50 | eggNOG-mapper | 1415774.U728_837 | phage terminase, large subunit, PBSX family | NA |
| UHGV-0019649_50 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0019649_50 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0019649_52 | KOfam | K01495 | GCH1, folE; GTP cyclohydrolase IA [EC:3.5.4.16] | NA |
| UHGV-0019649_52 | PHROG | phrog_2197 | GTP cyclohydrolase | other |
| UHGV-0019649_52 | UniRef90 | UniRef90_A0A6A8M5P4 | GTP cyclohydrolase 1 | NA |
| UHGV-0019649_52 | eggNOG-mapper | 411474.COPEUT_01542 | gtp cyclohydrolase i | NA |
| UHGV-0019649_52 | Pfam | PF01227 | GTP cyclohydrolase I | GTP_cyclohydroI |
| UHGV-0019649_52 | NCBIFam | NF006826.0 | GTP cyclohydrolase I FolE | NA |
| UHGV-0019649_52 | COG | COG0302 | GTP cyclohydrolase I | NA |
| UHGV-0019649_52 | HAMAP | MF_00223 | GTP cyclohydrolase 1 [folE] | NA |
| UHGV-0019649_52 | Structural annotation | PF01227, MF_00223, NF006826, COG0302 | NA | NA |
| UHGV-0019649_53 | KOfam | K10026 | queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] | NA |
| UHGV-0019649_53 | PHROG | phrog_2076 | QueE-like radical SAM domain | moron, auxiliary metabolic gene and host takeover |
| UHGV-0019649_53 | UniRef90 | UniRef90_A0A1I7FDL7 | 7-carboxy-7-deazaguanine synthase | NA |
| UHGV-0019649_53 | eggNOG-mapper | 351627.Csac_0105 | Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds | NA |
| UHGV-0019649_53 | Pfam | PF04055 | Radical SAM superfamily | Radical_SAM |
| UHGV-0019649_53 | COG | COG0602 | Organic radical activating enzyme NrdG/QueE | NA |
| UHGV-0019649_53 | HAMAP | MF_00917 | 7-carboxy-7-deazaguanine synthase [queE] | NA |
| UHGV-0019649_53 | Structural annotation | MF_00917, TIGR03963, COG0602 | NA | NA |
| UHGV-0019649_54 | UniRef90 | UniRef90_A0A7G7KRD4 | Phosphoribosyltransferase | NA |
| UHGV-0019649_54 | eggNOG-mapper | 64471.sync_1158 | Acts on guanine, xanthine and to a lesser extent hypoxanthine | NA |
| UHGV-0019649_54 | COG | COG2236 | Hypoxanthine phosphoribosyltransferase | NA |
| UHGV-0019649_55 | KOfam | K01737 | queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] | NA |
| UHGV-0019649_55 | PHROG | phrog_2389 | QueD-like 6-pyruvoyl-tetrahydropterin synthase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0019649_55 | UniRef90 | UniRef90_UPI000F8ECFA5 | 6-carboxytetrahydropterin synthase QueD | NA |
| UHGV-0019649_55 | eggNOG-mapper | 1064535.MELS_1152 | synthase | NA |
| UHGV-0019649_55 | Pfam | PF01242 | 6-pyruvoyl tetrahydropterin synthase | PTPS |
| UHGV-0019649_55 | NCBIFam | TIGR03367.1 | 6-carboxytetrahydropterin synthase QueD | NA |
| UHGV-0019649_55 | COG | COG0720 | 6-pyruvoyl-tetrahydropterin synthase | NA |
| UHGV-0019649_55 | Structural annotation | PF01242, TIGR00039, COG0720 | NA | NA |
| UHGV-0019649_56 | KOfam | K06920 | queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] | NA |
| UHGV-0019649_56 | PHROG | phrog_1550 | QueC-like queuosine biosynthesis | moron, auxiliary metabolic gene and host takeover |
| UHGV-0019649_56 | UniRef90 | UniRef90_R7FQI5 | 7-cyano-7-deazaguanine synthase | NA |
| UHGV-0019649_56 | eggNOG-mapper | 1408323.JQKK01000012_gene843 | Queuosine biosynthesis protein QueC | NA |
| UHGV-0019649_56 | PADLOC | QueC_00001 | QueC | CBASS |
| UHGV-0019649_56 | Pfam | PF06508 | Queuosine biosynthesis protein QueC | QueC |
| UHGV-0019649_56 | COG | COG0603 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis) | NA |
| UHGV-0019649_56 | Structural annotation | PF06508, MF_01633, TIGR00364, COG0603 | NA | NA |
| UHGV-0019649_57 | PHROG | phrog_887 | queuine tRNA-ribosyltransferase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0019649_57 | UniRef90 | UniRef90_R6N9F6 | Mycobacteriophage GP2 protein | NA |
| UHGV-0019649_57 | eggNOG-mapper | 445970.ALIPUT_02667 | NA | NA |
| UHGV-0019649_57 | Structural annotation | PF00290, MF_01634, TIGR00432, COG0269 | NA | NA |
| UHGV-0019649_59 | PHROG | phrog_620 | ParB-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-0019649_59 | UniRef90 | UniRef90_R6NR01 | Prophage LambdaWp4 DNA methylase | NA |
| UHGV-0019649_59 | eggNOG-mapper | 411459.RUMOBE_01044 | NA | NA |
| UHGV-0019649_59 | PADLOC | MTase_II_00015 | Type II methyltransferase | RM |
| UHGV-0019649_59 | Pfam | PF02195 | ParB/Sulfiredoxin domain | ParBc |
| UHGV-0019649_59 | COG | COG1475 | Chromosome segregation protein Spo0J, contains ParB-like nuclease domain | NA |
| UHGV-0019649_59 | Structural annotation | PF02195, MF_02015, TIGR04285, COG1475 | NA | NA |