| UHGV-0032722_2 | UniRef90 | UniRef90_A0A8D9PDQ6 | Restriction alleviation protein | NA |
| UHGV-0032722_2 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-0032722_2 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-0032722_2 | Structural annotation | PF14354, TIGR03655 | NA | NA |
| UHGV-0032722_7 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0032722_7 | UniRef90 | UniRef90_UPI001D0837DD | NA | NA |
| UHGV-0032722_7 | eggNOG-mapper | 580331.Thit_1400 | NA | NA |
| UHGV-0032722_7 | Structural annotation | PF07374, TIGR01636 | NA | NA |
| UHGV-0032722_8 | KOfam | K07319 | yhdJ; adenine-specific DNA-methyltransferase [EC:2.1.1.72] | NA |
| UHGV-0032722_8 | PHROG | phrog_498 | DNA methyltransferase | other |
| UHGV-0032722_8 | UniRef90 | UniRef90_A0A810Q3Z7 | N6_N4_Mtase domain-containing protein | NA |
| UHGV-0032722_8 | eggNOG-mapper | 1423758.BN55_01455 | DNA methylase | NA |
| UHGV-0032722_8 | PADLOC | MTase_II_00015 | Type II methyltransferase | RM |
| UHGV-0032722_8 | Pfam | PF02195 | ParB/Sulfiredoxin domain | ParBc |
| UHGV-0032722_8 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-0032722_8 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-0032722_8 | Structural annotation | PF01555, PF02195, MF_02015, MF_01872, NF010253, TIGR04285, COG0863, COG1475 | NA | NA |
| UHGV-0032722_10 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0032722_10 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-0032722_10 | UniRef90 | UniRef90_A0A3D3Y0N9 | PBSX family phage terminase large subunit | NA |
| UHGV-0032722_10 | eggNOG-mapper | 1226322.HMPREF1545_00043 | Phage terminase large subunit | NA |
| UHGV-0032722_10 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-0032722_10 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-0032722_10 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0032722_10 | Structural annotation | PF04466, PF17289, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0032722_11 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-0032722_11 | UniRef90 | UniRef90_UPI0018A8A301 | phage portal protein | NA |
| UHGV-0032722_11 | eggNOG-mapper | 1235800.C819_02239 | phage portal protein, SPP1 | NA |
| UHGV-0032722_11 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-0032722_11 | Structural annotation | PF05133, MF_04120, TIGR01538, COG3567 | NA | NA |
| UHGV-0032722_12 | PHROG | phrog_2468 | head morphogenesis | head and packaging |
| UHGV-0032722_12 | UniRef90 | UniRef90_A0A810PSD3 | Phage_Mu_F domain-containing protein | NA |
| UHGV-0032722_12 | eggNOG-mapper | 1504822.CCNO01000013_gene286 | cell adhesion | NA |
| UHGV-0032722_12 | Pfam | PF04233 | Phage Mu protein F like protein | Phage_Mu_F |
| UHGV-0032722_12 | COG | COG2369 | NA | NA |
| UHGV-0032722_12 | Structural annotation | PF04233, TIGR01641, COG2369 | NA | NA |
| UHGV-0032722_13 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-0032722_13 | UniRef90 | UniRef90_A0A4D7AJK9 | HK97 gp10 family phage protein | NA |
| UHGV-0032722_13 | eggNOG-mapper | 1123309.AQYB01000018_gene814 | Bacteriophage HK97-gp10, putative tail-component | NA |
| UHGV-0032722_13 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-0032722_13 | Structural annotation | PF20039, TIGR01725, COG5005 | NA | NA |
| UHGV-0032722_14 | PHROG | phrog_1233 | NA | unknown function |
| UHGV-0032722_14 | UniRef90 | UniRef90_UPI001C39EFB9 | Dienelactone hydrolase family protein | NA |
| UHGV-0032722_14 | eggNOG-mapper | 357809.Cphy_2967 | NA | NA |
| UHGV-0032722_15 | UniRef90 | UniRef90_A0A6B9SU02 | Fibronectin autolysin | NA |
| UHGV-0032722_15 | Structural annotation | PF06810 | NA | NA |
| UHGV-0032722_16 | PHROG | phrog_544 | major head protein | head and packaging |
| UHGV-0032722_16 | UniRef90 | UniRef90_UPI0019576143 | N4-gp56 family major capsid protein | NA |
| UHGV-0032722_16 | eggNOG-mapper | 411471.SUBVAR_06940 | NA | NA |
| UHGV-0032722_16 | NCBIFam | TIGR04387.1 | N4-gp56 family major capsid protein | NA |
| UHGV-0032722_16 | Structural annotation | PF05065, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-0032722_18 | PHROG | phrog_17977 | NA | unknown function |
| UHGV-0032722_18 | UniRef90 | UniRef90_UPI00141211AB | head-tail adaptor protein | NA |
| UHGV-0032722_18 | Structural annotation | PF07405, TIGR01563, COG5614 | NA | NA |
| UHGV-0032722_19 | PHROG | phrog_17405 | head protein | head and packaging |
| UHGV-0032722_19 | UniRef90 | UniRef90_A0A415JI88 | NA | NA |
| UHGV-0032722_19 | Structural annotation | PF11367 | NA | NA |
| UHGV-0032722_20 | PHROG | phrog_885 | major tail protein | tail |
| UHGV-0032722_20 | UniRef90 | UniRef90_A0A843J9F0 | Ig-like domain-containing protein | NA |
| UHGV-0032722_20 | eggNOG-mapper | 1504822.CCNO01000012_gene492 | NA | NA |
| UHGV-0032722_20 | Structural annotation | PF06488, TIGR01603, COG5437 | NA | NA |
| UHGV-0032722_21 | UniRef90 | UniRef90_A0A285PXU7 | Consensus disorder prediction | NA |
| UHGV-0032722_23 | PHROG | phrog_6900 | tail length tape measure protein | tail |
| UHGV-0032722_23 | eggNOG-mapper | 536233.CLO_1577 | tape measure | NA |
| UHGV-0032722_23 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0032722_24 | PHROG | phrog_33 | distal tail protein Dit | tail |
| UHGV-0032722_24 | UniRef90 | UniRef90_UPI0018A8B17A | phage tail family protein | NA |
| UHGV-0032722_24 | eggNOG-mapper | 1123263.AUKY01000068_gene490 | tail component | NA |
| UHGV-0032722_24 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0032722_24 | Structural annotation | PF20195, TIGR01633, COG4722 | NA | NA |
| UHGV-0032722_25 | PHROG | phrog_1067 | minor head protein | head and packaging |
| UHGV-0032722_25 | UniRef90 | UniRef90_A0A7G9G6Y3 | Phage tail protein | NA |
| UHGV-0032722_25 | eggNOG-mapper | 1123263.AUKY01000068_gene489 | Phage minor structural protein | NA |
| UHGV-0032722_25 | NCBIFam | TIGR01665.1 | phage tail spike protein | NA |
| UHGV-0032722_25 | COG | COG4926 | Phage-related protein | NA |
| UHGV-0032722_25 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-0032722_26 | Pfam | PF10651 | BppU N-terminal domain | BppU_N |
| UHGV-0032722_29 | PHROG | phrog_1863 | NA | unknown function |
| UHGV-0032722_29 | eggNOG-mapper | 665956.HMPREF1032_03922 | NA | NA |
| UHGV-0032722_30 | PHROG | phrog_443 | holin | lysis |
| UHGV-0032722_30 | Pfam | PF16945 | Putative lactococcus lactis phage r1t holin | Phage_r1t_holin |
| UHGV-0032722_30 | Structural annotation | PF16945 | NA | NA |
| UHGV-0032722_31 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-0032722_31 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-0032722_31 | UniRef90 | UniRef90_UPI00177FDC19 | LysM peptidoglycan-binding domain-containing protein | NA |
| UHGV-0032722_31 | eggNOG-mapper | 411470.RUMGNA_00451 | COG COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) | NA |
| UHGV-0032722_31 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-0032722_31 | COG | COG3023 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD | NA |
| UHGV-0032722_31 | Structural annotation | PF01183, NF007404, COG3757 | NA | NA |
| UHGV-0032722_32 | Structural annotation | PF16509, MF_00245, NF001066, COG2739 | NA | NA |
| UHGV-0032722_33 | PHROG | phrog_3754 | NA | unknown function |
| UHGV-0032722_33 | eggNOG-mapper | 1226322.HMPREF1545_00073 | NA | NA |
| UHGV-0032722_34 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-0032722_34 | eggNOG-mapper | 397290.C810_05210 | NA | NA |
| UHGV-0032722_35 | PHROG | phrog_22984 | NA | unknown function |
| UHGV-0032722_36 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0032722_36 | eggNOG-mapper | 1408437.JNJN01000043_gene803 | NA | NA |
| UHGV-0032722_37 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-0032722_37 | UniRef90 | UniRef90_A0A285PT46 | Tumour necrosis factor-like domain | NA |
| UHGV-0032722_37 | eggNOG-mapper | 397290.C810_05214 | NA | NA |
| UHGV-0032722_37 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-0032722_38 | eggNOG-mapper | 476272.RUMHYD_01772 | NA | NA |
| UHGV-0032722_38 | Structural annotation | PF12510 | NA | NA |
| UHGV-0032722_39 | eggNOG-mapper | 1226322.HMPREF1545_00079 | NA | NA |
| UHGV-0032722_40 | KOfam | K14059 | int; integrase | NA |
| UHGV-0032722_40 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0032722_40 | UniRef90 | UniRef90_A0A810Q0Y2 | Tyr recombinase domain-containing protein | NA |
| UHGV-0032722_40 | eggNOG-mapper | 693746.OBV_43340 | Belongs to the 'phage' integrase family | NA |
| UHGV-0032722_40 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0032722_40 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0032722_40 | Structural annotation | PF00589, PF13495, MF_02055, TIGR02225, COG4974 | NA | NA |
| UHGV-0032722_41 | Structural annotation | PF00356, TIGR02684, COG3636 | NA | NA |
| UHGV-0032722_43 | KOfam | K07504 | K07504; predicted type IV restriction endonuclease | NA |
| UHGV-0032722_43 | PHROG | phrog_4225 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0032722_43 | UniRef90 | UniRef90_UPI001BB478CB | type I restriction endonuclease | NA |
| UHGV-0032722_43 | eggNOG-mapper | 742738.HMPREF9460_04035 | Type I restriction enzyme R protein N terminus (HSDR_N) | NA |
| UHGV-0032722_43 | Pfam | PF04313 | Type I restriction enzyme R protein N terminus (HSDR_N) | HSDR_N |
| UHGV-0032722_43 | COG | COG4748 | NA | NA |
| UHGV-0032722_43 | Structural annotation | PF13588, TIGR04256, COG4748 | NA | NA |
| UHGV-0032722_45 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-0032722_45 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0032722_45 | UniRef90 | UniRef90_E2ZIF0 | DNA-binding helix-turn-helix protein | NA |
| UHGV-0032722_45 | eggNOG-mapper | 748224.HMPREF9436_01444 | NA | NA |
| UHGV-0032722_45 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-0032722_45 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0032722_45 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0032722_45 | Structural annotation | PF01381, MF_00535, NF007257, COG1396 | NA | NA |
| UHGV-0032722_47 | UniRef90 | UniRef90_A0A8D9PDN2 | DNA-binding protein | NA |
| UHGV-0032722_47 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0032722_47 | Structural annotation | PF10078, NF040507, COG3655 | NA | NA |
| UHGV-0032722_50 | PHROG | phrog_4392 | NA | unknown function |
| UHGV-0032722_52 | eggNOG-mapper | 1235835.C814_03153 | NA | NA |
| UHGV-0032722_52 | Structural annotation | PF09035, TIGR01764 | NA | NA |
| UHGV-0032722_53 | Structural annotation | PF19885 | NA | NA |
| UHGV-0032722_54 | KOfam | K23779 | sutR; XRE family transcriptional regulator, regulator of sulfur utilization | NA |
| UHGV-0032722_54 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0032722_54 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0032722_55 | PHROG | phrog_253 | Mu Gam-like end protection | DNA, RNA and nucleotide metabolism |
| UHGV-0032722_55 | UniRef90 | UniRef90_E2ZNS5 | Siphovirus Gp157 | NA |
| UHGV-0032722_55 | eggNOG-mapper | 748224.HMPREF9436_03356 | Siphovirus Gp157 | NA |
| UHGV-0032722_55 | Pfam | PF05565 | Siphovirus Gp157 | Sipho_Gp157 |
| UHGV-0032722_55 | Structural annotation | PF05565 | NA | NA |
| UHGV-0032722_56 | PHROG | phrog_7838 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0032722_56 | UniRef90 | UniRef90_A0A8D9UGW3 | DNA repair protein RAD52-like protein | NA |
| UHGV-0032722_56 | eggNOG-mapper | 742767.HMPREF9456_02052 | NA | NA |
| UHGV-0032722_56 | Structural annotation | PF04098, TIGR00607, COG4380 | NA | NA |
| UHGV-0032722_57 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-0032722_57 | UniRef90 | UniRef90_A0A8D9PDS2 | NinB protein | NA |
| UHGV-0032722_57 | eggNOG-mapper | 445972.ANACOL_01825 | NA | NA |
| UHGV-0032722_57 | Structural annotation | PF05772 | NA | NA |
| UHGV-0032722_58 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0032722_58 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0032722_58 | UniRef90 | UniRef90_A0A1C5QDM6 | Single-stranded DNA-binding protein | NA |
| UHGV-0032722_58 | eggNOG-mapper | 1226322.HMPREF1545_04080 | Single-strand binding protein family | NA |
| UHGV-0032722_58 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0032722_58 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0032722_58 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0032722_58 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0032722_58 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0032722_59 | PHROG | phrog_190 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0032722_59 | UniRef90 | UniRef90_UPI00164AE2A5 | NA | NA |
| UHGV-0032722_59 | eggNOG-mapper | 563031.HMPREF0666_01122 | NA | NA |
| UHGV-0032722_59 | Pfam | PF06356 | NA | DUF1064 |
| UHGV-0032722_59 | Structural annotation | PF06356 | NA | NA |
| UHGV-0032722_60 | PHROG | phrog_4973 | NA | unknown function |
| UHGV-0032722_60 | UniRef90 | UniRef90_UPI001D0904CC | helix-turn-helix domain-containing protein | NA |
| UHGV-0032722_60 | eggNOG-mapper | 935261.JAGL01000009_gene1175 | Helix-turn-helix domain | NA |
| UHGV-0032722_60 | Pfam | PF14090 | Helix-turn-helix domain | HTH_39 |
| UHGV-0032722_60 | Structural annotation | PF14090, NF040939, COG4738 | NA | NA |
| UHGV-0032722_61 | PHROG | phrog_11769 | NA | unknown function |
| UHGV-0032722_61 | UniRef90 | UniRef90_UPI0019617AF6 | phage replisome organizer N-terminal domain-containing protein | NA |
| UHGV-0032722_61 | eggNOG-mapper | 536232.CLM_1634 | N-terminal phage replisome organiser (Phage_rep_org_N) | NA |
| UHGV-0032722_61 | Pfam | PF09681 | N-terminal phage replisome organiser (Phage_rep_org_N) | Phage_rep_org_N |
| UHGV-0032722_61 | NCBIFam | TIGR01714.1 | phage replisome organizer, putative, N-terminal region | NA |
| UHGV-0032722_61 | Structural annotation | PF09681, TIGR01714, COG3355 | NA | NA |
| UHGV-0032722_62 | KOfam | K02315 | dnaC; DNA replication protein DnaC | NA |
| UHGV-0032722_62 | PHROG | phrog_50 | DnaC-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0032722_62 | UniRef90 | UniRef90_A0A4Z0Y679 | DNA replication protein DnaC | NA |
| UHGV-0032722_62 | eggNOG-mapper | 445972.ANACOL_01829 | NA | NA |
| UHGV-0032722_62 | Pfam | PF01695 | IstB-like ATP binding protein | IstB_IS21 |
| UHGV-0032722_62 | COG | COG1484 | DNA replication protein DnaC | NA |
| UHGV-0032722_62 | Structural annotation | PF01695, MF_01158, NF005378, COG1484 | NA | NA |
| UHGV-0032722_65 | KOfam | K00390 | cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] | NA |
| UHGV-0032722_65 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0032722_65 | UniRef90 | UniRef90_UPI001D087498 | phosphoadenosine phosphosulfate reductase family protein | NA |
| UHGV-0032722_65 | eggNOG-mapper | 1408437.JNJN01000032_gene2312 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-0032722_65 | PADLOC | BrxP_00001 | BrxP | BREX |
| UHGV-0032722_65 | Pfam | PF01507 | Phosphoadenosine phosphosulfate reductase family | PAPS_reduct |
| UHGV-0032722_65 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0032722_65 | Structural annotation | PF01507, MF_00063, NF010369, COG0175 | NA | NA |
| UHGV-0032722_67 | Structural annotation | PF06289, COG1582 | NA | NA |
| UHGV-0032722_69 | PHROG | phrog_2118 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0032722_69 | UniRef90 | UniRef90_A0A417HX51 | HNH endonuclease | NA |
| UHGV-0032722_69 | eggNOG-mapper | 742740.HMPREF9474_03129 | HNH endonuclease | NA |
| UHGV-0032722_69 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0032722_69 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0032722_69 | Structural annotation | PF14279, NF008448, COG1403 | NA | NA |