| UHGV-0031041_3 | PHROG | phrog_5889 | NA | unknown function |
| UHGV-0031041_3 | UniRef90 | UniRef90_A0A355ULX4 | HD domain-containing protein | NA |
| UHGV-0031041_3 | eggNOG-mapper | 1163671.JAGI01000002_gene1298 | Metal dependent phosphohydrolases with conserved 'HD' motif. | NA |
| UHGV-0031041_3 | Pfam | PF01966 | HD domain | HD |
| UHGV-0031041_3 | Structural annotation | PF01966, MF_01427, NF010007, COG3481 | NA | NA |
| UHGV-0031041_5 | UniRef90 | UniRef90_A0A843FND0 | BlaI/MecI/CopY family transcriptional regulator | NA |
| UHGV-0031041_5 | Structural annotation | PF20714, MF_01909, NF007467, COG4738 | NA | NA |
| UHGV-0031041_6 | Structural annotation | MF_00273 | NA | NA |
| UHGV-0031041_7 | Structural annotation | PF00679, MF_01515, NF003194, COG4843 | NA | NA |
| UHGV-0031041_9 | UniRef90 | UniRef90_A0A843FND0 | BlaI/MecI/CopY family transcriptional regulator | NA |
| UHGV-0031041_9 | Structural annotation | PF20714, MF_01909, NF007467, COG4738 | NA | NA |
| UHGV-0031041_12 | UniRef90 | UniRef90_A0A843FND0 | BlaI/MecI/CopY family transcriptional regulator | NA |
| UHGV-0031041_12 | Structural annotation | PF07106, MF_01177, NF033788, COG0640 | NA | NA |
| UHGV-0031041_14 | PHROG | phrog_20187 | NA | unknown function |
| UHGV-0031041_14 | Structural annotation | PF21762, MF_00045, NF006316, COG0847 | NA | NA |
| UHGV-0031041_15 | PHROG | phrog_8470 | NA | unknown function |
| UHGV-0031041_15 | eggNOG-mapper | 1410625.JHWK01000005_gene1301 | PcfJ-like protein | NA |
| UHGV-0031041_15 | Pfam | PF14284 | PcfJ-like protein | PcfJ |
| UHGV-0031041_15 | Structural annotation | PF14284 | NA | NA |
| UHGV-0031041_20 | KOfam | K08728 | E2.4.2.6; nucleoside deoxyribosyltransferase [EC:2.4.2.6] | NA |
| UHGV-0031041_20 | PHROG | phrog_7995 | nucleoside deoxyribosyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_20 | UniRef90 | UniRef90_R6N3L6 | Nucleoside 2-deoxyribosyltransferase | NA |
| UHGV-0031041_20 | eggNOG-mapper | 633697.EubceDRAFT1_0395 | Nucleoside 2-deoxyribosyltransferase | NA |
| UHGV-0031041_20 | Pfam | PF05014 | Nucleoside 2-deoxyribosyltransferase | Nuc_deoxyrib_tr |
| UHGV-0031041_20 | COG | COG3613 | Nucleoside 2-deoxyribosyltransferase | NA |
| UHGV-0031041_21 | Pfam | PF06941 | 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) | NT5C |
| UHGV-0031041_21 | Structural annotation | PF11019, MF_01022, NF003937, COG4502 | NA | NA |
| UHGV-0031041_35 | eggNOG-mapper | 1235798.C817_00271 | Histidine kinase | NA |
| UHGV-0031041_35 | COG | COG0642 | Signal transduction histidine kinase | NA |
| UHGV-0031041_37 | KOfam | K01491 | folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] | NA |
| UHGV-0031041_37 | PHROG | phrog_7320 | tetrahydrofolate dehydrogenase and cyclohydrolase | other |
| UHGV-0031041_37 | UniRef90 | UniRef90_A0A843FU99 | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase (Fragment) | NA |
| UHGV-0031041_37 | eggNOG-mapper | 796606.BMMGA3_11410 | Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate | NA |
| UHGV-0031041_37 | Pfam | PF00763 | Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain | THF_DHG_CYH |
| UHGV-0031041_37 | Pfam | PF02882 | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain | THF_DHG_CYH_C |
| UHGV-0031041_37 | COG | COG0190 | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | NA |
| UHGV-0031041_37 | HAMAP | MF_01576 | Bifunctional protein FolD [folD] | NA |
| UHGV-0031041_37 | Structural annotation | PF02882, PF00763, MF_01576, NF010775, COG0190 | NA | NA |
| UHGV-0031041_39 | PHROG | phrog_5767 | sigma factor | transcription regulation |
| UHGV-0031041_39 | UniRef90 | UniRef90_A0A345BPU6 | HTH DNA binding domain protein | NA |
| UHGV-0031041_39 | eggNOG-mapper | 1123239.KB898628_gene3218 | NA | NA |
| UHGV-0031041_40 | PHROG | phrog_3314 | NA | unknown function |
| UHGV-0031041_40 | eggNOG-mapper | 1308863.U5J9N3_9CAUD | NA | NA |
| UHGV-0031041_41 | PHROG | phrog_15503 | NA | unknown function |
| UHGV-0031041_41 | UniRef90 | UniRef90_A0A0H3V0N0 | Putative terminase large subunit | NA |
| UHGV-0031041_41 | eggNOG-mapper | 1560313.A0A0D3MT14_9CAUD | NA | NA |
| UHGV-0031041_41 | Structural annotation | PF20441, PF04466, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0031041_42 | PHROG | phrog_9084 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_42 | eggNOG-mapper | 397291.C804_06294 | transposase activity | NA |
| UHGV-0031041_42 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-0031041_42 | Structural annotation | PF18741, MF_04160, NF007294, COG2852 | NA | NA |
| UHGV-0031041_43 | PHROG | phrog_2739 | portal protein | head and packaging |
| UHGV-0031041_43 | UniRef90 | UniRef90_A0A345BPV2 | Putative portal protein | NA |
| UHGV-0031041_43 | eggNOG-mapper | 1308863.U5J9V5_9CAUD | NA | NA |
| UHGV-0031041_43 | Structural annotation | PF05133, MF_04135, TIGR01537, COG4695 | NA | NA |
| UHGV-0031041_44 | PHROG | phrog_3313 | NA | unknown function |
| UHGV-0031041_44 | UniRef90 | UniRef90_A0A843FJ52 | HALZ domain-containing protein | NA |
| UHGV-0031041_44 | eggNOG-mapper | 1308863.U5J9D4_9CAUD | NA | NA |
| UHGV-0031041_44 | Structural annotation | PF04586, TIGR01543, COG3566 | NA | NA |
| UHGV-0031041_46 | PHROG | phrog_4088 | NA | unknown function |
| UHGV-0031041_46 | eggNOG-mapper | 1541960.KQ78_01850 | NA | NA |
| UHGV-0031041_46 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0031041_47 | PHROG | phrog_30998 | NA | unknown function |
| UHGV-0031041_48 | PHROG | phrog_3853 | NA | unknown function |
| UHGV-0031041_49 | PHROG | phrog_29637 | NA | unknown function |
| UHGV-0031041_50 | PHROG | phrog_31155 | NA | unknown function |
| UHGV-0031041_50 | UniRef90 | UniRef90_A0A345BPV9 | Ig domain protein | NA |
| UHGV-0031041_50 | Structural annotation | PF19408, PF11649, NF041894, COG5614 | NA | NA |
| UHGV-0031041_51 | PHROG | phrog_6123 | virion structural protein | head and packaging |
| UHGV-0031041_51 | Structural annotation | PF06141 | NA | NA |
| UHGV-0031041_52 | PHROG | phrog_4051 | NA | unknown function |
| UHGV-0031041_52 | eggNOG-mapper | 1122918.KB907265_gene1066 | NA | NA |
| UHGV-0031041_53 | PHROG | phrog_2729 | virion structural protein | head and packaging |
| UHGV-0031041_53 | UniRef90 | UniRef90_E0YJ23 | Putative phage structural protein | NA |
| UHGV-0031041_53 | eggNOG-mapper | 1163671.JAGI01000002_gene1222 | NA | NA |
| UHGV-0031041_55 | PHROG | phrog_30570 | NA | unknown function |
| UHGV-0031041_56 | PHROG | phrog_4211 | tail length tape measure protein | tail |
| UHGV-0031041_56 | eggNOG-mapper | 224308.BSU21350 | COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) | NA |
| UHGV-0031041_56 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-0031041_56 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-0031041_56 | COG | COG0739 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain | NA |
| UHGV-0031041_58 | PHROG | phrog_1401 | NA | unknown function |
| UHGV-0031041_58 | UniRef90 | UniRef90_UPI00077668B1 | NA | NA |
| UHGV-0031041_58 | eggNOG-mapper | 1347392.CCEZ01000045_gene2 | NA | NA |
| UHGV-0031041_58 | Structural annotation | PF07761 | NA | NA |
| UHGV-0031041_59 | PHROG | phrog_30026 | NA | unknown function |
| UHGV-0031041_59 | Structural annotation | PF21821, PF12245, PF16974, PF17166, MF_04116, TIGR01633, TIGR03503, COG4228, COG4885 | NA | NA |
| UHGV-0031041_60 | PHROG | phrog_32343 | NA | unknown function |
| UHGV-0031041_60 | Structural annotation | PF05113, NF033848, COG4379 | NA | NA |
| UHGV-0031041_65 | PHROG | phrog_14959 | NA | unknown function |
| UHGV-0031041_65 | eggNOG-mapper | 762968.HMPREF9441_03606 | NA | NA |
| UHGV-0031041_67 | eggNOG-mapper | 1304866.K413DRAFT_4770 | PFAM Formylglycine-generating sulfatase enzyme | NA |
| UHGV-0031041_67 | COG | COG1262 | Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain | NA |
| UHGV-0031041_68 | eggNOG-mapper | 1304866.K413DRAFT_4770 | PFAM Formylglycine-generating sulfatase enzyme | NA |
| UHGV-0031041_68 | COG | COG1262 | Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain | NA |
| UHGV-0031041_68 | Structural annotation | PF10651 | NA | NA |
| UHGV-0031041_69 | COG | COG5301 | Phage-related tail fiber protein | NA |
| UHGV-0031041_71 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-0031041_71 | UniRef90 | UniRef90_A0A345BPX4 | Carbohydrate binding domain/collagen triple helix repeat protein | NA |
| UHGV-0031041_71 | eggNOG-mapper | 1226322.HMPREF1545_00077 | NA | NA |
| UHGV-0031041_71 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-0031041_72 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0031041_72 | eggNOG-mapper | 641112.ACOK01000103_gene525 | NA | NA |
| UHGV-0031041_73 | eggNOG-mapper | 658655.HMPREF0988_00918 | NA | NA |
| UHGV-0031041_74 | eggNOG-mapper | 445972.ANACOL_01878 | NA | NA |
| UHGV-0031041_75 | PHROG | phrog_13712 | holin | lysis |
| UHGV-0031041_75 | UniRef90 | UniRef90_A0A2P8EL22 | Superfamily 6 holin (LLH) | NA |
| UHGV-0031041_75 | eggNOG-mapper | 1227352.C173_31866 | NA | NA |
| UHGV-0031041_77 | KOfam | K01159 | ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] | NA |
| UHGV-0031041_77 | PHROG | phrog_827 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_77 | UniRef90 | UniRef90_A0A7K3Z7M4 | Crossover junction endodeoxyribonuclease RuvC | NA |
| UHGV-0031041_77 | eggNOG-mapper | 871968.DESME_08990 | NA | NA |
| UHGV-0031041_77 | Pfam | PF02075 | Crossover junction endodeoxyribonuclease RuvC | RuvC |
| UHGV-0031041_77 | Structural annotation | PF07066, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-0031041_78 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-0031041_78 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_78 | UniRef90 | UniRef90_A0A843FKH7 | dUTPase domain-containing protein (Fragment) | NA |
| UHGV-0031041_78 | eggNOG-mapper | 1158607.UAU_01270 | dUTPase | NA |
| UHGV-0031041_78 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-0031041_78 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-0031041_78 | Structural annotation | PF00692, MF_00116, NF010561, COG0756 | NA | NA |
| UHGV-0031041_79 | Structural annotation | PF10750, MF_01122, TIGR00285, COG1581 | NA | NA |
| UHGV-0031041_80 | Structural annotation | PF04937, MF_00034, NF001026, COG0816 | NA | NA |
| UHGV-0031041_81 | Structural annotation | PF20010 | NA | NA |
| UHGV-0031041_82 | KOfam | K04068 | nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] | NA |
| UHGV-0031041_82 | PHROG | phrog_626 | anaerobic ribonucleotide reductase small subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_82 | UniRef90 | UniRef90_A0A843FJD1 | Anaerobic ribonucleoside-triphosphate reductase activating protein | NA |
| UHGV-0031041_82 | eggNOG-mapper | 445973.CLOBAR_00582 | Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine | NA |
| UHGV-0031041_82 | Pfam | PF13353 | 4Fe-4S single cluster domain | Fer4_12 |
| UHGV-0031041_82 | NCBIFam | TIGR02491.1 | anaerobic ribonucleoside-triphosphate reductase activating protein | NA |
| UHGV-0031041_82 | COG | COG0602 | Organic radical activating enzyme NrdG/QueE | NA |
| UHGV-0031041_82 | Structural annotation | PF13353, MF_00917, TIGR02491, COG0602 | NA | NA |
| UHGV-0031041_83 | KOfam | K21636 | nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] | NA |
| UHGV-0031041_83 | PHROG | phrog_487 | NrdD-like anaerobic ribonucleotide reductase large subunit | moron, auxiliary metabolic gene and host takeover |
| UHGV-0031041_83 | UniRef90 | UniRef90_A0A3R6SNB8 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0031041_83 | eggNOG-mapper | 1304866.K413DRAFT_4593 | Ribonucleoside-triphosphate reductase | NA |
| UHGV-0031041_83 | Pfam | PF03477 | ATP cone domain | ATP-cone |
| UHGV-0031041_83 | Pfam | PF13597 | Anaerobic ribonucleoside-triphosphate reductase | NRDD |
| UHGV-0031041_83 | NCBIFam | TIGR02487.1 | anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0031041_83 | COG | COG1328 | Anaerobic ribonucleoside-triphosphate reductase | NA |
| UHGV-0031041_83 | Structural annotation | PF13597, PF03477, MF_00440, NF005497, COG1328 | NA | NA |
| UHGV-0031041_84 | KOfam | K00942 | gmk, GUK1; guanylate kinase [EC:2.7.4.8] | NA |
| UHGV-0031041_84 | PHROG | phrog_1815 | guanylate kinase | other |
| UHGV-0031041_84 | UniRef90 | UniRef90_A0A843FCP8 | Guanylate kinase-like domain-containing protein | NA |
| UHGV-0031041_84 | eggNOG-mapper | 877421.AUJT01000039_gene3559 | Guanylate kinase homologues. | NA |
| UHGV-0031041_84 | Pfam | PF00625 | Guanylate kinase | Guanylate_kin |
| UHGV-0031041_84 | COG | COG0194 | Guanylate kinase | NA |
| UHGV-0031041_84 | Structural annotation | PF00625, MF_00328, NF011324, COG0194 | NA | NA |
| UHGV-0031041_85 | KOfam | K02337 | dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] | NA |
| UHGV-0031041_85 | PHROG | phrog_405 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_85 | UniRef90 | UniRef90_A0A843FMN7 | DNA-directed DNA polymerase | NA |
| UHGV-0031041_85 | eggNOG-mapper | 224308.BSU20340 | DNA polymerase | NA |
| UHGV-0031041_85 | Pfam | PF02811 | PHP domain | PHP |
| UHGV-0031041_85 | Pfam | PF07733 | Bacterial DNA polymerase III alpha NTPase domain | DNA_pol3_alpha |
| UHGV-0031041_85 | Pfam | PF17657 | Bacterial DNA polymerase III alpha subunit finger domain | DNA_pol3_finger |
| UHGV-0031041_85 | Pfam | PF14579 | Helix-hairpin-helix motif | HHH_6 |
| UHGV-0031041_85 | COG | COG0587 | DNA polymerase III, alpha subunit | NA |
| UHGV-0031041_85 | Structural annotation | PF07733, PF02811, PF17657, PF14579, MF_01902, NF005617, COG0587 | NA | NA |
| UHGV-0031041_88 | PHROG | phrog_314 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_88 | UniRef90 | UniRef90_S1NAK7 | GIY-YIG domain-containing protein | NA |
| UHGV-0031041_88 | eggNOG-mapper | 1139219.I569_01385 | NUMOD3 motif (2 copies) | NA |
| UHGV-0031041_88 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0031041_88 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0031041_88 | Structural annotation | PF19835, TIGR01453 | NA | NA |
| UHGV-0031041_89 | KOfam | K03581 | recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] | NA |
| UHGV-0031041_89 | PHROG | phrog_325 | Dda-like helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_89 | UniRef90 | UniRef90_A0A843GQ82 | AAA family ATPase | NA |
| UHGV-0031041_89 | eggNOG-mapper | 1121085.AUCI01000012_gene2815 | A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD | NA |
| UHGV-0031041_89 | PADLOC | cluster10 | RecD_0_IVD | CRISPR-CAS |
| UHGV-0031041_89 | Pfam | PF13604 | AAA domain | AAA_30 |
| UHGV-0031041_89 | Pfam | PF13538 | UvrD-like helicase C-terminal domain | UvrD_C_2 |
| UHGV-0031041_89 | COG | COG0507 | ATPase/5'-3' helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) | NA |
| UHGV-0031041_89 | Structural annotation | PF13604, MF_01488, TIGR01448, COG0507 | NA | NA |
| UHGV-0031041_91 | UniRef90 | UniRef90_A0A843FTG5 | Phage_lysozyme2 domain-containing protein | NA |
| UHGV-0031041_91 | eggNOG-mapper | 768486.EHR_07585 | Bacteriophage peptidoglycan hydrolase | NA |
| UHGV-0031041_91 | Pfam | PF18013 | Phage tail lysozyme | Phage_lysozyme2 |
| UHGV-0031041_91 | COG | COG0791 | Cell wall-associated hydrolase, NlpC_P60 family | NA |
| UHGV-0031041_92 | KOfam | K07462 | recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] | NA |
| UHGV-0031041_92 | PHROG | phrog_2484 | RecJ-like ssDNA exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_92 | UniRef90 | UniRef90_A0A843FU26 | DHH family phosphoesterase | NA |
| UHGV-0031041_92 | eggNOG-mapper | 224308.BSU20350 | Single-stranded-DNA-specific exonuclease RecJ | NA |
| UHGV-0031041_92 | Pfam | PF01368 | DHH family | DHH |
| UHGV-0031041_92 | Pfam | PF17768 | RecJ OB domain | RecJ_OB |
| UHGV-0031041_92 | COG | COG0608 | ssDNA-specific exonuclease RecJ, DHH superfamily, may be involved in archaeal DNA replication intiation | NA |
| UHGV-0031041_92 | Structural annotation | PF17768, PF02272, MF_00207, TIGR00644, COG0608 | NA | NA |
| UHGV-0031041_94 | KOfam | K02316 | dnaG; DNA primase [EC:2.7.7.101] | NA |
| UHGV-0031041_94 | PHROG | phrog_47 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_94 | UniRef90 | UniRef90_A0A345BPU0 | DNA primase | NA |
| UHGV-0031041_94 | eggNOG-mapper | 224308.BSU20360 | DNA primase activity | NA |
| UHGV-0031041_94 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-0031041_94 | Structural annotation | PF01807, PF19898, MF_00974, NF006382, COG0358 | NA | NA |
| UHGV-0031041_97 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0031041_97 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_97 | UniRef90 | UniRef90_A0A843FNV1 | DNA helicase | NA |
| UHGV-0031041_97 | eggNOG-mapper | 224308.BSU20370 | DnaB-like helicase C terminal domain | NA |
| UHGV-0031041_97 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0031041_97 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0031041_97 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0031041_98 | PHROG | phrog_4680 | NA | unknown function |
| UHGV-0031041_98 | UniRef90 | UniRef90_A0A3S4N9I4 | NA | NA |
| UHGV-0031041_98 | eggNOG-mapper | 1541960.KQ78_01918 | NA | NA |
| UHGV-0031041_98 | Structural annotation | PF02069 | NA | NA |
| UHGV-0031041_99 | PHROG | phrog_124 | Sak4-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_99 | UniRef90 | UniRef90_A0A843GMB3 | ATP-binding protein | NA |
| UHGV-0031041_99 | eggNOG-mapper | 1541960.KQ78_01919 | Belongs to the helicase family. UvrD subfamily | NA |
| UHGV-0031041_99 | Pfam | PF13479 | AAA domain | AAA_24 |
| UHGV-0031041_99 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-0031041_99 | Structural annotation | PF13479, MF_00350, TIGR01618, COG0468 | NA | NA |
| UHGV-0031041_100 | Structural annotation | PF00436, PF19649, MF_00984, NF004476, COG2965 | NA | NA |
| UHGV-0031041_101 | UniRef90 | UniRef90_A0A843FPF0 | Winged helix-turn-helix domain-containing protein | NA |
| UHGV-0031041_101 | Pfam | PF13463 | Winged helix DNA-binding domain | HTH_27 |
| UHGV-0031041_101 | Structural annotation | PF03444, MF_00732, TIGR02337, COG1321 | NA | NA |
| UHGV-0031041_102 | KOfam | K00287 | DHFR, folA; dihydrofolate reductase [EC:1.5.1.3] | NA |
| UHGV-0031041_102 | PHROG | phrog_316 | dihydrofolate reductase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_102 | UniRef90 | UniRef90_UPI000730C6C7 | dihydrofolate reductase | NA |
| UHGV-0031041_102 | eggNOG-mapper | 1408823.AXUS01000015_gene1433 | Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis | NA |
| UHGV-0031041_102 | Pfam | PF00186 | Dihydrofolate reductase | DHFR_1 |
| UHGV-0031041_102 | COG | COG0262 | Dihydrofolate reductase | NA |
| UHGV-0031041_102 | Structural annotation | PF00186, MF_01547, NF040541, COG0262 | NA | NA |
| UHGV-0031041_103 | KOfam | K00560 | thyA, TYMS; thymidylate synthase [EC:2.1.1.45] | NA |
| UHGV-0031041_103 | PHROG | phrog_5682 | thymidylate synthase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_103 | UniRef90 | UniRef90_A0A843FJ47 | Thymidylate synthase | NA |
| UHGV-0031041_103 | eggNOG-mapper | 1410633.JHWR01000014_gene1762 | Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | NA |
| UHGV-0031041_103 | Pfam | PF00303 | Thymidylate synthase | Thymidylat_synt |
| UHGV-0031041_103 | COG | COG0207 | Thymidylate synthase | NA |
| UHGV-0031041_103 | HAMAP | MF_00008 | Thymidylate synthase [thyA] | NA |
| UHGV-0031041_103 | Structural annotation | PF00303, MF_00008, NF002497, COG0207 | NA | NA |
| UHGV-0031041_105 | PHROG | phrog_314 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_105 | UniRef90 | UniRef90_A0A843FP25 | GIY-YIG nuclease family protein | NA |
| UHGV-0031041_105 | eggNOG-mapper | 742735.HMPREF9467_00770 | GIY-YIG type nucleases (URI domain) | NA |
| UHGV-0031041_105 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0031041_105 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0031041_105 | Structural annotation | PF19835, TIGR01453 | NA | NA |
| UHGV-0031041_106 | UniRef90 | UniRef90_A0A345BPT3 | SarR-like protein | NA |
| UHGV-0031041_106 | Structural annotation | PF04182, MF_01909, NF040939, COG1675 | NA | NA |
| UHGV-0031041_108 | KOfam | K01972 | E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2] | NA |
| UHGV-0031041_108 | PHROG | phrog_3869 | NAD-dependent DNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_108 | UniRef90 | UniRef90_A0A843FQD5 | DNA ligase | NA |
| UHGV-0031041_108 | eggNOG-mapper | 411470.RUMGNA_00017 | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA | NA |
| UHGV-0031041_108 | Pfam | PF01653 | NAD-dependent DNA ligase adenylation domain | DNA_ligase_aden |
| UHGV-0031041_108 | Pfam | PF03120 | NAD-dependent DNA ligase OB-fold domain | DNA_ligase_OB |
| UHGV-0031041_108 | Pfam | PF00533 | BRCA1 C Terminus (BRCT) domain | BRCT |
| UHGV-0031041_108 | NCBIFam | NF005932.1 | NAD-dependent DNA ligase LigA | NA |
| UHGV-0031041_108 | COG | COG0272 | NAD-dependent DNA ligase | NA |
| UHGV-0031041_108 | HAMAP | MF_01588 | DNA ligase [ligA] | NA |
| UHGV-0031041_108 | Structural annotation | PF01653, PF03120, PF00533, MF_01588, NF005932, COG0272 | NA | NA |
| UHGV-0031041_109 | KOfam | K21993 | fdhC; formate transporter | NA |
| UHGV-0031041_109 | UniRef90 | UniRef90_UPI00101C227B | formate/nitrite transporter family protein | NA |
| UHGV-0031041_109 | eggNOG-mapper | 1408416.JNJT01000013_gene466 | formate transmembrane transporter activity | NA |
| UHGV-0031041_109 | Pfam | PF01226 | Formate/nitrite transporter | Form_Nir_trans |
| UHGV-0031041_109 | COG | COG2116 | Formate/nitrite transporter FocA, FNT family | NA |
| UHGV-0031041_109 | Structural annotation | PF01226, MF_01146, NF007261, COG2116 | NA | NA |
| UHGV-0031041_110 | KOfam | K02469 | gyrA; DNA gyrase subunit A [EC:5.6.2.2] | NA |
| UHGV-0031041_110 | PHROG | phrog_551 | DNA topoisomerase II | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_110 | UniRef90 | UniRef90_A0A843FHT1 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0031041_110 | eggNOG-mapper | 720554.Clocl_4221 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0031041_110 | Pfam | PF00521 | DNA gyrase/topoisomerase IV, subunit A | DNA_topoisoIV |
| UHGV-0031041_110 | Pfam | PF03989 | DNA gyrase C-terminal domain, beta-propeller | DNA_gyraseA_C |
| UHGV-0031041_110 | NCBIFam | NF004044.1 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0031041_110 | COG | COG0188 | DNA gyrase/topoisomerase IV, subunit A | NA |
| UHGV-0031041_110 | Structural annotation | PF00521, PF03989, MF_01897, NF004043, COG0188 | NA | NA |
| UHGV-0031041_111 | KOfam | K03469 | rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4] | NA |
| UHGV-0031041_111 | PHROG | phrog_531 | Rnase H | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_111 | UniRef90 | UniRef90_A0A843FJ64 | Ribonuclease H | NA |
| UHGV-0031041_111 | eggNOG-mapper | 526224.Bmur_0317 | Endonuclease that specifically degrades the RNA of RNA- DNA hybrids | NA |
| UHGV-0031041_111 | Pfam | PF00075 | RNase H | RNase_H |
| UHGV-0031041_111 | COG | COG0328 | Ribonuclease HI | NA |
| UHGV-0031041_111 | Structural annotation | PF00075, MF_00042, NF001236, COG0328 | NA | NA |
| UHGV-0031041_113 | KOfam | K02470 | gyrB; DNA gyrase subunit B [EC:5.6.2.2] | NA |
| UHGV-0031041_113 | PHROG | phrog_543 | DNA topoisomerase II large subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_113 | UniRef90 | UniRef90_A0A345BPY9 | DNA topoisomerase (ATP-hydrolyzing) | NA |
| UHGV-0031041_113 | eggNOG-mapper | 1235802.C823_01372 | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | NA |
| UHGV-0031041_113 | Pfam | PF02518 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | HATPase_c |
| UHGV-0031041_113 | Pfam | PF00204 | DNA gyrase B | DNA_gyraseB |
| UHGV-0031041_113 | Pfam | PF01751 | Toprim domain | Toprim |
| UHGV-0031041_113 | Pfam | PF00986 | DNA gyrase B subunit, carboxyl terminus | DNA_gyraseB_C |
| UHGV-0031041_113 | COG | COG0187 | DNA gyrase/topoisomerase IV, subunit B | NA |
| UHGV-0031041_113 | Structural annotation | PF00204, MF_01898, TIGR01059, COG0187 | NA | NA |
| UHGV-0031041_114 | KOfam | K06871 | NA | NA |
| UHGV-0031041_114 | PHROG | phrog_1802 | radical SAM domain-containing protein | other |
| UHGV-0031041_114 | UniRef90 | UniRef90_A0A4U7JHJ7 | Radical SAM protein | NA |
| UHGV-0031041_114 | eggNOG-mapper | 411467.BACCAP_00969 | 4Fe-4S single cluster domain | NA |
| UHGV-0031041_114 | PADLOC | pVip-lone | Viperins not associated with kinases | Viperin |
| UHGV-0031041_114 | Pfam | PF04055 | Radical SAM superfamily | Radical_SAM |
| UHGV-0031041_114 | COG | COG0641 | Sulfatase maturation enzyme AslB, radical SAM superfamily | NA |
| UHGV-0031041_114 | Structural annotation | PF04055, MF_00660, TIGR04103, COG0535 | NA | NA |
| UHGV-0031041_116 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0031041_116 | PHROG | phrog_1794 | amidase | lysis |
| UHGV-0031041_116 | UniRef90 | UniRef90_A0A374UNP8 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0031041_116 | eggNOG-mapper | 1203606.HMPREF1526_01931 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0031041_116 | Pfam | PF05257 | CHAP domain | CHAP |
| UHGV-0031041_116 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0031041_116 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0031041_117 | KOfam | K07175 | phoH2; PhoH-like ATPase | NA |
| UHGV-0031041_117 | PHROG | phrog_2765 | PhoH-like phosphate starvation-inducible | other |
| UHGV-0031041_117 | UniRef90 | UniRef90_A0A1C5UCD2 | PhoH-like protein | NA |
| UHGV-0031041_117 | eggNOG-mapper | 411470.RUMGNA_00090 | PIN domain | NA |
| UHGV-0031041_117 | Pfam | PF13638 | PIN domain | PIN_4 |
| UHGV-0031041_117 | Pfam | PF02562 | PhoH-like protein | PhoH |
| UHGV-0031041_117 | COG | COG1875 | Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains | NA |
| UHGV-0031041_117 | Structural annotation | PF02562, PF13638, PF09142, MF_00265, NF007827, NF009148, COG1875 | NA | NA |
| UHGV-0031041_119 | Structural annotation | PF13876, NF011863 | NA | NA |
| UHGV-0031041_120 | KOfam | K07192 | FLOT; flotillin | NA |
| UHGV-0031041_120 | UniRef90 | UniRef90_G2SYE3 | Flotillin 2 | NA |
| UHGV-0031041_120 | eggNOG-mapper | 585394.RHOM_13935 | SPFH Band 7 PHB domain protein | NA |
| UHGV-0031041_120 | Pfam | PF01145 | SPFH domain / Band 7 family | Band_7 |
| UHGV-0031041_120 | COG | COG2268 | NA | NA |
| UHGV-0031041_120 | Structural annotation | PF01145, MF_01562, NF008181, COG2268 | NA | NA |
| UHGV-0031041_121 | KOfam | K07099 | NA | NA |
| UHGV-0031041_121 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-0031041_121 | UniRef90 | UniRef90_A0A1I0M725 | Calcineurin-like phosphoesterase superfamily protein | NA |
| UHGV-0031041_121 | eggNOG-mapper | 1392491.JIAE01000001_gene1129 | Calcineurin-like phosphoesterase | NA |
| UHGV-0031041_121 | Pfam | PF12850 | Calcineurin-like phosphoesterase superfamily domain | Metallophos_2 |
| UHGV-0031041_121 | COG | COG4186 | NA | NA |
| UHGV-0031041_121 | Structural annotation | NF006988, COG4186 | NA | NA |
| UHGV-0031041_122 | PHROG | phrog_6931 | NA | unknown function |
| UHGV-0031041_122 | UniRef90 | UniRef90_A0A6J5MD33 | Selen_PSTK, L-seryl-tRNA(Sec) kinase | NA |
| UHGV-0031041_122 | Pfam | PF13671 | AAA domain | AAA_33 |
| UHGV-0031041_122 | Structural annotation | PF13671, MF_00065, TIGR03574, COG4088 | NA | NA |
| UHGV-0031041_123 | Structural annotation | PF00471, MF_00294, TIGR01023, COG0267 | NA | NA |
| UHGV-0031041_125 | KOfam | K01939 | purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4] | NA |
| UHGV-0031041_125 | PHROG | phrog_1211 | adenylosuccinate synthetase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0031041_125 | UniRef90 | UniRef90_A0A4U8Q465 | Adenylosuccinate synthetase | NA |
| UHGV-0031041_125 | eggNOG-mapper | 180332.JTGN01000003_gene2162 | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP | NA |
| UHGV-0031041_125 | Pfam | PF00709 | Adenylosuccinate synthetase | Adenylsucc_synt |
| UHGV-0031041_125 | COG | COG0104 | Adenylosuccinate synthase | NA |
| UHGV-0031041_125 | Structural annotation | PF00709, MF_00011, NF010355, COG0104 | NA | NA |
| UHGV-0031041_127 | PHROG | phrog_2971 | NA | unknown function |
| UHGV-0031041_127 | UniRef90 | UniRef90_UPI00164B073B | VWA domain-containing protein | NA |
| UHGV-0031041_127 | eggNOG-mapper | 1392493.JIAB01000001_gene1822 | NA | NA |
| UHGV-0031041_127 | Structural annotation | PF00092, MF_01340, NF003711, COG4867 | NA | NA |
| UHGV-0031041_128 | Structural annotation | PF13973, TIGR00739, COG1862 | NA | NA |
| UHGV-0031041_130 | KOfam | K07313 | pphA; serine/threonine protein phosphatase 1 [EC:3.1.3.16] | NA |
| UHGV-0031041_130 | PHROG | phrog_246 | NinI-like serine-threonine phosphatase | other |
| UHGV-0031041_130 | UniRef90 | UniRef90_A0A0D6APV2 | Serine/threonine protein phosphatase | NA |
| UHGV-0031041_130 | eggNOG-mapper | 1410674.JNKU01000042_gene2159 | Serine Threonine protein | NA |
| UHGV-0031041_130 | Pfam | PF12850 | Calcineurin-like phosphoesterase superfamily domain | Metallophos_2 |
| UHGV-0031041_130 | COG | COG0639 | Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family | NA |
| UHGV-0031041_130 | Structural annotation | PF12850, MF_01443, NF007425, COG0622 | NA | NA |
| UHGV-0031041_132 | Structural annotation | PF01978, MF_01819, NF012168, COG0735 | NA | NA |
| UHGV-0031041_134 | Structural annotation | MF_00085, NF008465 | NA | NA |
| UHGV-0031041_138 | KOfam | K09117 | NA | NA |
| UHGV-0031041_138 | PHROG | phrog_1460 | tRNA amidotransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_138 | UniRef90 | UniRef90_A5Z5W7 | YqeY-like protein | NA |
| UHGV-0031041_138 | eggNOG-mapper | 411463.EUBVEN_01099 | NA | NA |
| UHGV-0031041_138 | Pfam | PF09424 | Yqey-like protein | YqeY |
| UHGV-0031041_138 | COG | COG1610 | NA | NA |
| UHGV-0031041_138 | Structural annotation | PF09424, COG1610 | NA | NA |
| UHGV-0031041_139 | PHROG | phrog_968 | RNA ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_139 | UniRef90 | UniRef90_A0A3B9Z7W5 | RNA_ligase domain-containing protein | NA |
| UHGV-0031041_139 | eggNOG-mapper | 1122176.KB903554_gene3905 | RNA ligase | NA |
| UHGV-0031041_139 | Pfam | PF21189 | PHA02142 OB-fold domain | PHA02142 |
| UHGV-0031041_139 | Pfam | PF09414 | RNA ligase | RNA_ligase |
| UHGV-0031041_139 | COG | COG0073 | tRNA-binding EMAP/Myf domain | NA |
| UHGV-0031041_139 | Structural annotation | PF21189, PF09511, MF_04150, TIGR02306, COG1423, COG0073 | NA | NA |
| UHGV-0031041_144 | PHROG | phrog_839 | NA | unknown function |
| UHGV-0031041_145 | KOfam | K02342 | dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] | NA |
| UHGV-0031041_145 | PHROG | phrog_192 | DNA polymerase exonuclease subunit | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_145 | UniRef90 | UniRef90_UPI0019171D70 | exonuclease domain-containing protein | NA |
| UHGV-0031041_145 | eggNOG-mapper | 6412.HelroP113361 | exoribonuclease 1 | NA |
| UHGV-0031041_145 | PADLOC | cd06127 | CAS-I,CAS-II,CAS-III,CAS-IV,CAS-V,CAS-VI; associated | CRISPR-CAS |
| UHGV-0031041_145 | Pfam | PF00929 | Exonuclease | RNase_T |
| UHGV-0031041_145 | COG | COG5018 | 3'-5' exonuclease KapD, inhibitor of KinA-controlled sporulation | NA |
| UHGV-0031041_145 | Structural annotation | PF00929, MF_00977, NF005838, COG5018 | NA | NA |
| UHGV-0031041_146 | eggNOG-mapper | 1256908.HMPREF0373_01589 | NA | NA |
| UHGV-0031041_146 | Pfam | PF20274 | Cyclic-phosphate processing Receiver domain | cREC_REC |
| UHGV-0031041_146 | Structural annotation | PF20274 | NA | NA |
| UHGV-0031041_149 | PHROG | phrog_1649 | metallo-phosphoesterase | other |
| UHGV-0031041_149 | UniRef90 | UniRef90_A0A843H0H1 | Metallophosphoesterase | NA |
| UHGV-0031041_149 | eggNOG-mapper | 411490.ANACAC_01436 | metallophosphoesterase | NA |
| UHGV-0031041_149 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0031041_149 | COG | COG1408 | Predicted phosphohydrolase, MPP superfamily | NA |
| UHGV-0031041_149 | Structural annotation | PF14582, MF_00575, TIGR03729, COG2129 | NA | NA |
| UHGV-0031041_150 | KOfam | K07074 | NA | NA |
| UHGV-0031041_150 | PHROG | phrog_388 | nucleotidyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_150 | UniRef90 | UniRef90_A0A843FSU3 | Nucleotidyltransferase domain-containing protein | NA |
| UHGV-0031041_150 | eggNOG-mapper | 1236973.JCM9157_1946 | Predicted nucleotidyltransferase | NA |
| UHGV-0031041_150 | Pfam | PF10127 | RNA repair pathway DNA polymerase beta family | RlaP |
| UHGV-0031041_150 | Structural annotation | PF10127, NF000079, COG3541 | NA | NA |
| UHGV-0031041_151 | KOfam | K21138 | HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2] | NA |
| UHGV-0031041_151 | PHROG | phrog_990 | metal-dependent phosphohydrolase | other |
| UHGV-0031041_151 | UniRef90 | UniRef90_A0A371ATQ4 | HD domain-containing protein | NA |
| UHGV-0031041_151 | eggNOG-mapper | 1235802.C823_04738 | NA | NA |
| UHGV-0031041_151 | Structural annotation | PF13328 | NA | NA |
| UHGV-0031041_152 | KOfam | K10761 | THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79] | NA |
| UHGV-0031041_152 | PHROG | phrog_4717 | tRNA-His guanylyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_152 | UniRef90 | UniRef90_A0A415MDY8 | Thg1 domain-containing protein | NA |
| UHGV-0031041_152 | eggNOG-mapper | 742735.HMPREF9467_00875 | tRNAHis guanylyltransferase | NA |
| UHGV-0031041_152 | Pfam | PF04446 | tRNAHis guanylyltransferase | Thg1 |
| UHGV-0031041_152 | COG | COG4021 | tRNA(His) 5'-end guanylyltransferase | NA |
| UHGV-0031041_152 | Structural annotation | PF04446, PF14413, COG4021 | NA | NA |
| UHGV-0031041_154 | UniRef90 | UniRef90_R9JN75 | NA | NA |
| UHGV-0031041_154 | eggNOG-mapper | 397291.C804_01014 | NA | NA |
| UHGV-0031041_154 | Pfam | PF10021 | Microbial-type PARG, catalytic domain | PARG_cat_microb |
| UHGV-0031041_154 | NCBIFam | TIGR02452.1 | TIGR02452 family protein | NA |
| UHGV-0031041_154 | COG | COG4295 | NA | NA |
| UHGV-0031041_154 | Structural annotation | PF10021, MF_01205, TIGR02452, COG4295 | NA | NA |
| UHGV-0031041_156 | KOfam | K00600 | glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] | NA |
| UHGV-0031041_156 | PHROG | phrog_9968 | methyltransferase | other |
| UHGV-0031041_156 | UniRef90 | UniRef90_A0A3D2FYD5 | Serine hydroxymethyltransferase | NA |
| UHGV-0031041_156 | eggNOG-mapper | 883109.HMPREF0380_01006 | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | NA |
| UHGV-0031041_156 | Pfam | PF00464 | Serine hydroxymethyltransferase | SHMT |
| UHGV-0031041_156 | NCBIFam | NF000586.1 | serine hydroxymethyltransferase | NA |
| UHGV-0031041_156 | COG | COG0112 | Glycine/serine hydroxymethyltransferase | NA |
| UHGV-0031041_156 | HAMAP | MF_00051 | Serine hydroxymethyltransferase [glyA] | NA |
| UHGV-0031041_156 | Structural annotation | PF00464, MF_00051, NF000586, COG0112 | NA | NA |
| UHGV-0031041_157 | KOfam | K14445 | SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 | NA |
| UHGV-0031041_157 | UniRef90 | UniRef90_A0A1G4FM50 | Na(+)/dicarboxylate symporter | NA |
| UHGV-0031041_157 | eggNOG-mapper | 469618.FVAG_01517 | Sodium:sulfate symporter transmembrane region | NA |
| UHGV-0031041_157 | Pfam | PF00939 | Sodium:sulfate symporter transmembrane region | Na_sulph_symp |
| UHGV-0031041_157 | COG | COG0471 | Di- and tricarboxylate antiporter | NA |
| UHGV-0031041_158 | KOfam | K14187 | tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12] | NA |
| UHGV-0031041_158 | PHROG | phrog_10027 | NA | unknown function |
| UHGV-0031041_158 | eggNOG-mapper | 1158345.JNLL01000001_gene1814 | Prephenate dehydratase | NA |
| UHGV-0031041_158 | Pfam | PF01817 | Chorismate mutase type II | CM_2 |
| UHGV-0031041_158 | COG | COG0077 | Prephenate dehydratase | NA |
| UHGV-0031041_158 | Structural annotation | PF01817, TIGR01791, COG1605 | NA | NA |
| UHGV-0031041_159 | PHROG | phrog_850 | RNA-binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_159 | UniRef90 | UniRef90_A0A843FJC6 | NA | NA |
| UHGV-0031041_159 | eggNOG-mapper | 1541960.KQ78_01972 | oxidoreductase activity | NA |
| UHGV-0031041_159 | Pfam | PF11443 | NA | DUF2828 |
| UHGV-0031041_159 | COG | COG2304 | Secreted protein containing bacterial Ig-like domain and vWFA domain | NA |
| UHGV-0031041_159 | Structural annotation | PF11443, MF_01340, COG2304 | NA | NA |
| UHGV-0031041_162 | PHROG | phrog_5018 | NA | unknown function |
| UHGV-0031041_162 | UniRef90 | UniRef90_A0A7W0ZJN3 | PDDEXK_5 domain-containing protein | NA |
| UHGV-0031041_162 | eggNOG-mapper | 547559.Nmag_2148 | PD-(D/E)XK endonuclease | NA |
| UHGV-0031041_162 | Pfam | PF11645 | PD-(D/E)XK endonuclease | PDDEXK_5 |
| UHGV-0031041_162 | Structural annotation | PF11645, MF_01490, NF011271, COG4815 | NA | NA |
| UHGV-0031041_163 | Structural annotation | PF08962 | NA | NA |
| UHGV-0031041_164 | KOfam | K03651 | cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] | NA |
| UHGV-0031041_164 | UniRef90 | UniRef90_A0A843FBH5 | Metallophosphoesterase | NA |
| UHGV-0031041_164 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0031041_165 | PHROG | phrog_19111 | NA | unknown function |
| UHGV-0031041_165 | eggNOG-mapper | 1121335.Clst_0408 | ATPase involved in DNA repair | NA |
| UHGV-0031041_165 | COG | COG0419 | DNA repair exonuclease SbcCD ATPase subunit | NA |
| UHGV-0031041_167 | PHROG | phrog_33094 | NA | unknown function |
| UHGV-0031041_168 | PHROG | phrog_35541 | NA | unknown function |
| UHGV-0031041_168 | eggNOG-mapper | 411470.RUMGNA_00120 | NA | NA |
| UHGV-0031041_170 | PHROG | phrog_25979 | NA | unknown function |
| UHGV-0031041_170 | eggNOG-mapper | 1151292.QEW_0665 | NA | NA |
| UHGV-0031041_171 | Structural annotation | PF20010 | NA | NA |
| UHGV-0031041_172 | eggNOG-mapper | 1410626.JHXB01000004_gene213 | NA | NA |
| UHGV-0031041_172 | Pfam | PF09479 | Listeria-Bacteroides repeat domain (List_Bact_rpt) | Flg_new |
| UHGV-0031041_172 | NCBIFam | TIGR02543.1 | TIGR02543 family repeat protein | NA |
| UHGV-0031041_172 | COG | COG1579 | Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain | NA |
| UHGV-0031041_173 | PHROG | phrog_2376 | ATPase | other |
| UHGV-0031041_173 | UniRef90 | UniRef90_A0A1C6AGW6 | ATPase family associated with various cellular activities (AAA) | NA |
| UHGV-0031041_173 | eggNOG-mapper | 1235790.C805_03653 | ATPase family associated with various cellular activities (AAA) | NA |
| UHGV-0031041_173 | Pfam | PF00004 | ATPase family associated with various cellular activities (AAA) | AAA |
| UHGV-0031041_173 | COG | COG1222 | ATP-dependent 26S proteasome regulatory subunit | NA |
| UHGV-0031041_173 | Structural annotation | PF05673, MF_00553, TIGR01242, COG0464 | NA | NA |
| UHGV-0031041_174 | UniRef90 | UniRef90_A0A417JTJ0 | Polya polymerase | NA |
| UHGV-0031041_174 | eggNOG-mapper | 1007096.BAGW01000018_gene677 | NA | NA |
| UHGV-0031041_174 | Structural annotation | NF008146, COG1925 | NA | NA |
| UHGV-0031041_175 | PHROG | phrog_7168 | homing endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_175 | UniRef90 | UniRef90_A0A349YKA3 | GIY-YIG domain-containing protein | NA |
| UHGV-0031041_175 | eggNOG-mapper | 702450.CUW_1847 | GIY-YIG catalytic domain | NA |
| UHGV-0031041_175 | PADLOC | HEase_00030 | homing endonuclease | RM |
| UHGV-0031041_175 | Pfam | PF01541 | GIY-YIG catalytic domain | GIY-YIG |
| UHGV-0031041_175 | NCBIFam | TIGR01453.1 | group I intron endonuclease | NA |
| UHGV-0031041_175 | Structural annotation | PF19835, PF13518, PF07453, TIGR01453 | NA | NA |
| UHGV-0031041_177 | PHROG | phrog_10822 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0031041_177 | UniRef90 | UniRef90_F7K085 | HNHc domain-containing protein | NA |
| UHGV-0031041_177 | eggNOG-mapper | 1157637.KB892155_gene7647 | HNH endonuclease | NA |
| UHGV-0031041_177 | PADLOC | HEase_00002 | homing endonuclease | RM |
| UHGV-0031041_177 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0031041_179 | UniRef90 | UniRef90_G8LSC5 | Collagenase-like protease | NA |
| UHGV-0031041_179 | eggNOG-mapper | 1341157.RF007C_15095 | peptidase U32 | NA |
| UHGV-0031041_179 | COG | COG0826 | 23S rRNA C2501 and tRNA U34 5'-hydroxylation protein RlhA/YrrN/YrrO, U32 peptidase family | NA |
| UHGV-0031041_179 | Structural annotation | PF02219, MF_02232, NF011996, COG0826 | NA | NA |
| UHGV-0031041_180 | eggNOG-mapper | 140626.JHWB01000009_gene1426 | NA | NA |
| UHGV-0031041_180 | COG | COG0826 | 23S rRNA C2501 and tRNA U34 5'-hydroxylation protein RlhA/YrrN/YrrO, U32 peptidase family | NA |
| UHGV-0031041_180 | Structural annotation | PF02219, MF_02232, NF011996, COG0826 | NA | NA |
| UHGV-0031041_182 | KOfam | K06871 | NA | NA |
| UHGV-0031041_182 | UniRef90 | UniRef90_A0A662M7Z1 | Radical SAM core domain-containing protein | NA |
| UHGV-0031041_182 | Structural annotation | MF_00660, TIGR04115, COG0535 | NA | NA |
| UHGV-0031041_184 | KOfam | K06871 | NA | NA |
| UHGV-0031041_184 | PHROG | phrog_1802 | radical SAM domain-containing protein | other |
| UHGV-0031041_184 | Pfam | PF04055 | Radical SAM superfamily | Radical_SAM |
| UHGV-0031041_187 | KOfam | K03086 | rpoD; RNA polymerase primary sigma factor | NA |
| UHGV-0031041_187 | PHROG | phrog_351 | RNA polymerase sigma factor | transcription regulation |
| UHGV-0031041_187 | UniRef90 | UniRef90_A0A3D4MUQ4 | RNA polymerase sigma factor SigA | NA |
| UHGV-0031041_187 | eggNOG-mapper | 1382358.JHVN01000001_gene941 | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth | NA |
| UHGV-0031041_187 | PADLOC | MzaA_00001 | NA | mzaABCDE |
| UHGV-0031041_187 | Pfam | PF00140 | Sigma-70 factor, region 1.2 | Sigma70_r1_2 |
| UHGV-0031041_187 | Pfam | PF04542 | Sigma-70 region 2 | Sigma70_r2 |
| UHGV-0031041_187 | Pfam | PF04539 | Sigma-70 region 3 | Sigma70_r3 |
| UHGV-0031041_187 | Pfam | PF04545 | Sigma-70, region 4 | Sigma70_r4 |
| UHGV-0031041_187 | NCBIFam | TIGR02937.1 | sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-0031041_187 | COG | COG0568 | DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) | NA |
| UHGV-0031041_187 | Structural annotation | PF04542, PF04539, MF_00959, NF005920, COG0568 | NA | NA |
| UHGV-0031041_190 | PHROG | phrog_18912 | NA | unknown function |
| UHGV-0031041_190 | eggNOG-mapper | 935948.KE386495_gene2241 | NA | NA |
| UHGV-0031041_191 | KOfam | K01258 | pepT; tripeptide aminopeptidase [EC:3.4.11.4] | NA |
| UHGV-0031041_191 | PHROG | phrog_34186 | NA | unknown function |
| UHGV-0031041_191 | UniRef90 | UniRef90_A0A843FNS9 | M28 family peptidase | NA |
| UHGV-0031041_191 | eggNOG-mapper | 935948.KE386495_gene2240 | Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls | NA |
| UHGV-0031041_191 | Pfam | PF01546 | Peptidase family M20/M25/M40 | Peptidase_M20 |
| UHGV-0031041_191 | COG | COG0624 | Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase | NA |
| UHGV-0031041_191 | Structural annotation | PF05343, MF_01120, TIGR01883, COG1363 | NA | NA |
| UHGV-0031041_192 | Structural annotation | PF02581, MF_02232, TIGR01182, COG0135 | NA | NA |
| UHGV-0031041_193 | Structural annotation | PF04182, MF_01586, NF040939, COG0735 | NA | NA |
| UHGV-0031041_194 | eggNOG-mapper | 411467.BACCAP_03130 | NA | NA |
| UHGV-0031041_196 | PHROG | phrog_20678 | NA | unknown function |
| UHGV-0031041_196 | eggNOG-mapper | 1005058.UMN179_01817 | NA | NA |
| UHGV-0031041_197 | PHROG | phrog_547 | phosphoesterase | other |
| UHGV-0031041_197 | UniRef90 | UniRef90_A0A843FNF2 | Metallophosphoesterase | NA |
| UHGV-0031041_197 | eggNOG-mapper | 1410632.JHWW01000019_gene1481 | NA | NA |
| UHGV-0031041_197 | Pfam | PF00149 | Calcineurin-like phosphoesterase | Metallophos |
| UHGV-0031041_197 | Structural annotation | MF_00575, TIGR04123, COG4186 | NA | NA |
| UHGV-0031041_198 | PHROG | phrog_2319 | NA | unknown function |
| UHGV-0031041_198 | UniRef90 | UniRef90_UPI0006A7B5FD | zinc finger-like domain-containing protein | NA |
| UHGV-0031041_198 | eggNOG-mapper | 713586.KB900537_gene3115 | NA | NA |
| UHGV-0031041_198 | Structural annotation | PF17768, MF_01959, NF009635, COG0048 | NA | NA |
| UHGV-0031041_200 | PHROG | phrog_2316 | NA | unknown function |
| UHGV-0031041_200 | UniRef90 | UniRef90_A0A4P8KL08 | NA | NA |
| UHGV-0031041_200 | eggNOG-mapper | 1280676.AUJO01000024_gene3262 | NA | NA |
| UHGV-0031041_200 | Pfam | PF16475 | NA | DUF5052 |
| UHGV-0031041_200 | Structural annotation | PF16475, MF_00436, NF033216, COG1923 | NA | NA |
| UHGV-0031041_203 | Structural annotation | PF16857, MF_00273, NF001981, COG2157 | NA | NA |
| UHGV-0031041_205 | UniRef90 | UniRef90_A0A843FJ99 | CopG family transcriptional regulator | NA |
| UHGV-0031041_205 | Pfam | PF19807 | NA | DUF6290 |
| UHGV-0031041_206 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-0031041_206 | Structural annotation | PF19808 | NA | NA |