| UHGV-1371882_1 | KOfam | K14059 | int; integrase | NA |
| UHGV-1371882_1 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-1371882_1 | UniRef90 | UniRef90_A0A173REA3 | Site-specific tyrosine recombinase XerD | NA |
| UHGV-1371882_1 | eggNOG-mapper | 397291.C804_00897 | Phage integrase family | NA |
| UHGV-1371882_1 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-1371882_1 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-1371882_1 | Structural annotation | PF00589, PF02920, MF_02055, TIGR02224, COG4974 | NA | NA |
| UHGV-1371882_2 | UniRef90 | UniRef90_A0A173RE24 | Bacterial regulatory proteins, luxR family | NA |
| UHGV-1371882_2 | Pfam | PF00196 | Bacterial regulatory proteins, luxR family | GerE |
| UHGV-1371882_2 | Structural annotation | PF00196, MF_00245, NF001067, COG2771 | NA | NA |
| UHGV-1371882_3 | KOfam | K00571 | E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72] | NA |
| UHGV-1371882_3 | PHROG | phrog_23224 | DNA methyltransferase | other |
| UHGV-1371882_3 | UniRef90 | UniRef90_A0A3R6JG61 | Methyltransferase | NA |
| UHGV-1371882_3 | eggNOG-mapper | 1123304.AQYA01000037_gene207 | DNA methylase | NA |
| UHGV-1371882_3 | PADLOC | MTase_II_00157 | Type II methyltransferase | RM |
| UHGV-1371882_3 | Pfam | PF01555 | DNA methylase | N6_N4_Mtase |
| UHGV-1371882_3 | COG | COG0863 | DNA modification methylase | NA |
| UHGV-1371882_3 | Structural annotation | PF01555, NF010253, COG0863 | NA | NA |
| UHGV-1371882_5 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1371882_5 | UniRef90 | UniRef90_A0A6L6XK67 | Phosphoadenosine phosphosulfate reductase | NA |
| UHGV-1371882_5 | eggNOG-mapper | 1410650.JHWL01000037_gene617 | sulfate reduction | NA |
| UHGV-1371882_5 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-1371882_5 | Structural annotation | PF01507, MF_00063, NF002537, COG0175 | NA | NA |
| UHGV-1371882_8 | PHROG | phrog_874 | NA | unknown function |
| UHGV-1371882_8 | eggNOG-mapper | 411468.CLOSCI_00298 | NA | NA |
| UHGV-1371882_8 | Structural annotation | PF04266, MF_00684, NF003443, COG4405 | NA | NA |
| UHGV-1371882_10 | PHROG | phrog_20593 | NA | unknown function |
| UHGV-1371882_11 | eggNOG-mapper | 742740.HMPREF9474_03128 | NA | NA |
| UHGV-1371882_13 | PHROG | phrog_15198 | NA | unknown function |
| UHGV-1371882_13 | UniRef90 | UniRef90_A0A6N7XMA0 | NA | NA |
| UHGV-1371882_13 | Pfam | PF04448 | NA | DUF551 |
| UHGV-1371882_13 | Structural annotation | PF21627 | NA | NA |
| UHGV-1371882_14 | PHROG | phrog_21026 | NA | unknown function |
| UHGV-1371882_18 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-1371882_18 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-1371882_18 | UniRef90 | UniRef90_A0A1Q9J827 | DNA helicase | NA |
| UHGV-1371882_18 | eggNOG-mapper | 1298920.KI911353_gene2061 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-1371882_18 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-1371882_18 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-1371882_18 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-1371882_18 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-1371882_19 | PHROG | phrog_11769 | NA | unknown function |
| UHGV-1371882_19 | UniRef90 | UniRef90_A0A173RDT0 | Phage replisome organizer, putative, N-terminal region | NA |
| UHGV-1371882_19 | eggNOG-mapper | 536232.CLM_1634 | N-terminal phage replisome organiser (Phage_rep_org_N) | NA |
| UHGV-1371882_19 | Pfam | PF09681 | N-terminal phage replisome organiser (Phage_rep_org_N) | Phage_rep_org_N |
| UHGV-1371882_19 | NCBIFam | TIGR01714.1 | phage replisome organizer, putative, N-terminal region | NA |
| UHGV-1371882_19 | Structural annotation | PF09681, TIGR01714, COG3388 | NA | NA |
| UHGV-1371882_20 | PHROG | phrog_19106 | NA | unknown function |
| UHGV-1371882_20 | UniRef90 | UniRef90_A0A412RQV5 | GIY-YIG nuclease family protein | NA |
| UHGV-1371882_20 | eggNOG-mapper | 658655.HMPREF0988_00875 | NA | NA |
| UHGV-1371882_20 | Structural annotation | TIGR01453 | NA | NA |
| UHGV-1371882_23 | KOfam | K06167 | phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55] | NA |
| UHGV-1371882_23 | PHROG | phrog_392 | metal-dependent hydrolase | other |
| UHGV-1371882_23 | UniRef90 | UniRef90_A0A173REW9 | Beta-lactamase superfamily domain | NA |
| UHGV-1371882_23 | eggNOG-mapper | 1144313.PMI10_00501 | Metallo-beta-lactamase superfamily | NA |
| UHGV-1371882_23 | Pfam | PF12706 | Beta-lactamase superfamily domain | Lactamase_B_2 |
| UHGV-1371882_23 | COG | COG1235 | Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase | NA |
| UHGV-1371882_23 | Structural annotation | PF02112, MF_01818, NF041851, COG1234 | NA | NA |
| UHGV-1371882_24 | PHROG | phrog_25456 | NA | unknown function |
| UHGV-1371882_26 | PHROG | phrog_2185 | RecT-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-1371882_26 | UniRef90 | UniRef90_UPI00189B4EB8 | recombinase RecT | NA |
| UHGV-1371882_26 | eggNOG-mapper | 658655.HMPREF0988_00886 | NA | NA |
| UHGV-1371882_26 | Pfam | PF03837 | RecT family | RecT |
| UHGV-1371882_26 | Structural annotation | NF007351, COG3723 | NA | NA |
| UHGV-1371882_29 | PHROG | phrog_2164 | NA | unknown function |
| UHGV-1371882_29 | eggNOG-mapper | 1232453.BAIF02000057_gene1135 | NA | NA |
| UHGV-1371882_30 | PHROG | phrog_4400 | NA | unknown function |
| UHGV-1371882_30 | eggNOG-mapper | 886882.PPSC2_p0514 | NA | NA |
| UHGV-1371882_30 | dbAPIS | APIS008 | Alphafold2 predicted that Gad2 is an enzyme with a nucleotidyltransferase protein domain, suggesting that it inhibits Gabija via a mechanism of action different than Gad1. | NA |
| UHGV-1371882_30 | Structural annotation | PF01743, MF_00957, TIGR01942, COG0617 | NA | NA |
| UHGV-1371882_31 | KOfam | K19171 | dndD; DNA sulfur modification protein DndD | NA |
| UHGV-1371882_31 | PHROG | phrog_77 | SbcC-like subunit of palindrome specific endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-1371882_31 | UniRef90 | UniRef90_UPI001D02FD96 | AAA family ATPase | NA |
| UHGV-1371882_31 | eggNOG-mapper | 1294142.CINTURNW_1008 | nuclear chromosome segregation | NA |
| UHGV-1371882_31 | Pfam | PF13476 | AAA domain | AAA_23 |
| UHGV-1371882_31 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-1371882_31 | Structural annotation | PF02463, MF_00449, NF041034, COG0419 | NA | NA |
| UHGV-1371882_32 | PHROG | phrog_26861 | NA | unknown function |
| UHGV-1371882_32 | UniRef90 | UniRef90_A0A173RCS5 | Single-stranded DNA-binding protein | NA |
| UHGV-1371882_32 | eggNOG-mapper | 1408823.AXUS01000016_gene1024 | Single-strand binding protein family | NA |
| UHGV-1371882_32 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-1371882_32 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-1371882_32 | Structural annotation | PF00436, PF13567, MF_00984, NF004476, COG0629 | NA | NA |
| UHGV-1371882_36 | PHROG | phrog_4608 | anti-repressor | transcription regulation |
| UHGV-1371882_36 | UniRef90 | UniRef90_A0A173RD24 | ORF6N domain | NA |
| UHGV-1371882_36 | eggNOG-mapper | 1408823.AXUS01000024_gene2689 | ORF6C domain | NA |
| UHGV-1371882_36 | Pfam | PF10543 | ORF6N domain | ORF6N |
| UHGV-1371882_36 | COG | COG3646 | Phage regulatory protein Rha | NA |
| UHGV-1371882_39 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-1371882_39 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-1371882_39 | UniRef90 | UniRef90_A0A1Q6LL24 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-1371882_39 | eggNOG-mapper | 642492.Clole_0718 | DNA-binding helix-turn-helix protein | NA |
| UHGV-1371882_39 | PADLOC | retron_type_VI_hth_cluster2_1 | NA | Retron |
| UHGV-1371882_39 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-1371882_39 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-1371882_39 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-1371882_40 | NCBIFam | NF040910.1 | CD1375 family protein | NA |
| UHGV-1371882_40 | Structural annotation | NF040910 | NA | NA |
| UHGV-1371882_41 | eggNOG-mapper | 610130.Closa_0760 | NA | NA |
| UHGV-1371882_43 | PHROG | phrog_17196 | kinase | other |
| UHGV-1371882_43 | eggNOG-mapper | 483218.BACPEC_01141 | NA | NA |
| UHGV-1371882_43 | Structural annotation | PF19537, PF13619, COG3536 | NA | NA |
| UHGV-1371882_44 | PHROG | phrog_18190 | NA | unknown function |
| UHGV-1371882_44 | UniRef90 | UniRef90_A0A173UFM3 | Peptidase S74 domain-containing protein | NA |
| UHGV-1371882_44 | eggNOG-mapper | 397290.C810_05239 | NA | NA |
| UHGV-1371882_44 | Pfam | PF13884 | Chaperone of endosialidase | Peptidase_S74 |
| UHGV-1371882_44 | Structural annotation | PF05113, NF033848, COG3500 | NA | NA |
| UHGV-1371882_45 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-1371882_45 | Pfam | PF20458 | NA | DUF6711 |
| UHGV-1371882_45 | Structural annotation | PF20458, TIGR01633, COG3499 | NA | NA |
| UHGV-1371882_46 | PHROG | phrog_130 | anti-repressor Ant | transcription regulation |
| UHGV-1371882_46 | UniRef90 | UniRef90_A0A1I0BKG6 | BRO family, N-terminal domain | NA |
| UHGV-1371882_46 | eggNOG-mapper | 1443125.Z962_p0009 | BRO family, N-terminal domain | NA |
| UHGV-1371882_46 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-1371882_46 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-1371882_46 | Structural annotation | PF02498, COG3617 | NA | NA |
| UHGV-1371882_47 | UniRef90 | UniRef90_A0A173UG14 | BIG2 domain-containing protein | NA |
| UHGV-1371882_47 | eggNOG-mapper | 1410624.JNKK01000088_gene2110 | Bacterial Ig-like domain (group 2) | NA |
| UHGV-1371882_47 | Structural annotation | PF02368, PF07233, NF038353, NF005261 | NA | NA |
| UHGV-1371882_48 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-1371882_48 | UniRef90 | UniRef90_A0A173UHS1 | Phage-related protein | NA |
| UHGV-1371882_48 | eggNOG-mapper | 1211844.CBLM010000016_gene1482 | tape measure | NA |
| UHGV-1371882_48 | COG | COG3941 | Phage tail tape-measure protein, controls tail length | NA |
| UHGV-1371882_48 | Structural annotation | PF20155, MF_04138 | NA | NA |
| UHGV-1371882_49 | PHROG | phrog_14030 | NA | unknown function |
| UHGV-1371882_49 | UniRef90 | UniRef90_A0A3R6ARM6 | Peptidoglycan-binding protein | NA |
| UHGV-1371882_49 | eggNOG-mapper | 1235793.C809_02691 | N-Acetylmuramoyl-L-alanine amidase | NA |
| UHGV-1371882_49 | COG | COG3023 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD | NA |
| UHGV-1371882_52 | UniRef90 | UniRef90_A0A8D9PGN2 | Major tail protein | NA |
| UHGV-1371882_52 | Structural annotation | PF16463, TIGR02126, COG5437 | NA | NA |
| UHGV-1371882_53 | Structural annotation | PF05657 | NA | NA |
| UHGV-1371882_54 | eggNOG-mapper | 1298920.KI911353_gene2654 | NA | NA |
| UHGV-1371882_54 | AcrCatalog | cluster_24841 | NA | NA |
| UHGV-1371882_55 | Structural annotation | PF07405, TIGR01563, COG5614 | NA | NA |
| UHGV-1371882_56 | PHROG | phrog_443 | holin | lysis |
| UHGV-1371882_56 | UniRef90 | UniRef90_UPI000BA3B743 | holin | NA |
| UHGV-1371882_56 | eggNOG-mapper | 411490.ANACAC_00704 | Putative lactococcus lactis phage r1t holin | NA |
| UHGV-1371882_56 | Pfam | PF16945 | Putative lactococcus lactis phage r1t holin | Phage_r1t_holin |
| UHGV-1371882_56 | Structural annotation | PF16945 | NA | NA |
| UHGV-1371882_57 | PHROG | phrog_4105 | NA | unknown function |
| UHGV-1371882_57 | eggNOG-mapper | 411459.RUMOBE_00911 | NA | NA |
| UHGV-1371882_58 | eggNOG-mapper | 397290.C810_01402 | NA | NA |
| UHGV-1371882_59 | PHROG | phrog_774 | NA | unknown function |
| UHGV-1371882_59 | eggNOG-mapper | 397290.C810_05225 | NA | NA |
| UHGV-1371882_60 | UniRef90 | UniRef90_A0A416G2T8 | Rho_N domain-containing protein | NA |
| UHGV-1371882_60 | Structural annotation | PF21169 | NA | NA |
| UHGV-1371882_61 | PHROG | phrog_29 | major head protein | head and packaging |
| UHGV-1371882_61 | UniRef90 | UniRef90_UPI001D02C54B | major capsid protein | NA |
| UHGV-1371882_61 | eggNOG-mapper | 1298920.KI911353_gene2660 | Phage major capsid protein E | NA |
| UHGV-1371882_61 | Pfam | PF03864 | Phage major capsid protein E | Phage_cap_E |
| UHGV-1371882_61 | Structural annotation | PF03864, MF_04133, NF041162, COG4653 | NA | NA |
| UHGV-1371882_62 | PHROG | phrog_909 | major head protein | head and packaging |
| UHGV-1371882_62 | eggNOG-mapper | 1298920.KI911353_gene2661 | NA | NA |
| UHGV-1371882_63 | UniRef90 | UniRef90_R6C0B6 | Phage capsid scaffolding protein | NA |
| UHGV-1371882_64 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-1371882_64 | UniRef90 | UniRef90_A0A173UGW9 | Phage portal protein, SPP1 family | NA |
| UHGV-1371882_64 | eggNOG-mapper | 1298920.KI911353_gene2663 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1371882_64 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-1371882_64 | Structural annotation | PF05133, MF_04120, TIGR01538, COG5511 | NA | NA |
| UHGV-1371882_65 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-1371882_65 | UniRef90 | UniRef90_A0A410QFZ6 | NA | NA |
| UHGV-1371882_65 | eggNOG-mapper | 994573.T472_0211085 | sigma factor activity | NA |
| UHGV-1371882_65 | COG | COG1191 | DNA-directed RNA polymerase specialized sigma subunit | NA |
| UHGV-1371882_65 | Structural annotation | PF07374, MF_00674, NF008895, COG1191 | NA | NA |
| UHGV-1371882_66 | PHROG | phrog_38 | terminase large subunit | head and packaging |
| UHGV-1371882_66 | UniRef90 | UniRef90_A0A8D9PG33 | Terminase | NA |
| UHGV-1371882_66 | eggNOG-mapper | 1232453.BAIF02000058_gene1623 | TIGRFAM Phage | NA |
| UHGV-1371882_66 | COG | COG5410 | NA | NA |
| UHGV-1371882_66 | Structural annotation | PF17289, PF02562, MF_04147, NF033889, COG5362, COG5410 | NA | NA |
| UHGV-1371882_67 | PHROG | phrog_1233 | NA | unknown function |
| UHGV-1371882_67 | UniRef90 | UniRef90_UPI001C39EFB9 | Dienelactone hydrolase family protein | NA |
| UHGV-1371882_67 | eggNOG-mapper | 357809.Cphy_2967 | NA | NA |
| UHGV-1371882_67 | Structural annotation | PF13058 | NA | NA |
| UHGV-1371882_73 | Structural annotation | PF04466 | NA | NA |
| UHGV-1371882_77 | eggNOG-mapper | 411473.RUMCAL_02525 | NA | NA |
| UHGV-1371882_78 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-1371882_78 | UniRef90 | UniRef90_R6C0D1 | MazG nucleotide pyrophosphohydrolase domain | NA |
| UHGV-1371882_78 | eggNOG-mapper | 428125.CLOLEP_01391 | MazG nucleotide pyrophosphohydrolase domain | NA |
| UHGV-1371882_78 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-1371882_78 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-1371882_78 | Structural annotation | PF03819, MF_01020, NF001613, COG0140 | NA | NA |
| UHGV-1371882_79 | eggNOG-mapper | 658655.HMPREF0988_00895 | NA | NA |
| UHGV-1371882_82 | UniRef90 | UniRef90_UPI001D008199 | helix-turn-helix domain-containing protein | NA |
| UHGV-1371882_82 | eggNOG-mapper | 877411.JMMA01000002_gene1483 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-1371882_82 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-1371882_86 | Structural annotation | PF20593 | NA | NA |
| UHGV-1371882_87 | Structural annotation | PF13973 | NA | NA |
| UHGV-1371882_90 | UniRef90 | UniRef90_A0A173UED2 | Predicted transcriptional regulator | NA |
| UHGV-1371882_90 | eggNOG-mapper | 1280689.AUJC01000024_gene150 | Cro/C1-type HTH DNA-binding domain | NA |
| UHGV-1371882_91 | PHROG | phrog_373 | anti-repressor | transcription regulation |
| UHGV-1371882_91 | UniRef90 | UniRef90_UPI001C02FA3A | Rha family transcriptional regulator | NA |
| UHGV-1371882_91 | eggNOG-mapper | 1235793.C809_02221 | Phage regulatory protein Rha (Phage_pRha) | NA |
| UHGV-1371882_91 | Pfam | PF09669 | Phage regulatory protein Rha (Phage_pRha) | Phage_pRha |
| UHGV-1371882_91 | COG | COG3646 | Phage regulatory protein Rha | NA |
| UHGV-1371882_91 | Structural annotation | PF09669, TIGR02681, COG3646 | NA | NA |
| UHGV-1371882_94 | PHROG | phrog_1233 | NA | unknown function |
| UHGV-1371882_94 | eggNOG-mapper | 658655.HMPREF0988_00914 | NA | NA |
| UHGV-1371882_95 | eggNOG-mapper | 658655.HMPREF0988_00915 | NA | NA |
| UHGV-1371882_96 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-1371882_96 | UniRef90 | UniRef90_A0A285PT46 | Tumour necrosis factor-like domain | NA |
| UHGV-1371882_96 | eggNOG-mapper | 397290.C810_05214 | NA | NA |
| UHGV-1371882_96 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-1371882_97 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1371882_97 | eggNOG-mapper | 397290.C810_01328 | NA | NA |
| UHGV-1371882_98 | eggNOG-mapper | 658655.HMPREF0988_00918 | NA | NA |
| UHGV-1371882_99 | eggNOG-mapper | 658655.HMPREF0988_00919 | NA | NA |