| UHGV-0114224_1 | UniRef90 | UniRef90_UPI00049F0CB1 | methyltransferase | NA |
| UHGV-0114224_1 | eggNOG-mapper | 1300150.EMQU_2283 | methyltransferase | NA |
| UHGV-0114224_1 | PADLOC | MTase_II_00074 | Type II methyltransferase | RM |
| UHGV-0114224_1 | COG | COG0500 | SAM-dependent methyltransferase | NA |
| UHGV-0114224_2 | UniRef90 | UniRef90_A0A3E5E9F8 | DNA-binding protein | NA |
| UHGV-0114224_2 | Pfam | PF12728 | Helix-turn-helix domain | HTH_17 |
| UHGV-0114224_2 | Structural annotation | PF05930, TIGR01764, COG3311 | NA | NA |
| UHGV-0114224_3 | eggNOG-mapper | 679190.HMPREF0650_1967 | NA | NA |
| UHGV-0114224_4 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0114224_4 | PHROG | phrog_822 | amidase | lysis |
| UHGV-0114224_4 | UniRef90 | UniRef90_K1SWX0 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0114224_4 | eggNOG-mapper | 1127696.HMPREF9134_00800 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0114224_4 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0114224_4 | COG | COG3023 | N-acetyl-anhydromuramyl-L-alanine amidase AmpD | NA |
| UHGV-0114224_4 | Structural annotation | PF01510, MF_04111, NF008758, COG3023 | NA | NA |
| UHGV-0114224_5 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0114224_5 | UniRef90 | UniRef90_UPI00189871DD | NUMOD4 domain-containing protein | NA |
| UHGV-0114224_5 | eggNOG-mapper | 357276.EL88_11520 | HNH endonuclease domain protein | NA |
| UHGV-0114224_5 | PADLOC | HEase_00016 | homing endonuclease | RM |
| UHGV-0114224_5 | Pfam | PF07463 | NUMOD4 motif | NUMOD4 |
| UHGV-0114224_5 | Pfam | PF13392 | HNH endonuclease | HNH_3 |
| UHGV-0114224_5 | Pfam | PF07453 | NUMOD1 domain | NUMOD1 |
| UHGV-0114224_5 | Structural annotation | PF07453, TIGR01453 | NA | NA |
| UHGV-0114224_6 | PHROG | phrog_20732 | NA | unknown function |
| UHGV-0114224_6 | UniRef90 | UniRef90_A0A6G7X1I7 | Phage holin family protein | NA |
| UHGV-0114224_6 | eggNOG-mapper | 742727.HMPREF9447_04857 | NA | NA |
| UHGV-0114224_6 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-0114224_8 | PHROG | phrog_27246 | NA | unknown function |
| UHGV-0114224_9 | PHROG | phrog_32516 | NA | unknown function |
| UHGV-0114224_9 | eggNOG-mapper | 1227276.HMPREF9148_00144 | NA | NA |
| UHGV-0114224_9 | Structural annotation | PF11134, COG2706 | NA | NA |
| UHGV-0114224_10 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-0114224_10 | UniRef90 | UniRef90_UPI001C38A690 | terminase | NA |
| UHGV-0114224_10 | eggNOG-mapper | 1347393.HG726020_gene1832 | Mu-like prophage FluMu protein gp28 | NA |
| UHGV-0114224_10 | COG | COG4373 | Mu-like prophage FluMu protein gp28 | NA |
| UHGV-0114224_10 | Structural annotation | PF03354, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0114224_13 | Structural annotation | PF02368 | NA | NA |
| UHGV-0114224_15 | PHROG | phrog_156 | portal protein | head and packaging |
| UHGV-0114224_15 | eggNOG-mapper | 1227276.HMPREF9148_00164 | NA | NA |
| UHGV-0114224_15 | Structural annotation | PF16510, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-0114224_16 | PHROG | phrog_22323 | NA | unknown function |
| UHGV-0114224_16 | eggNOG-mapper | 563031.HMPREF0666_01148 | NA | NA |
| UHGV-0114224_17 | PHROG | phrog_26635 | NA | unknown function |
| UHGV-0114224_17 | Structural annotation | PF17236, MF_04133, TIGR01554, COG4653 | NA | NA |
| UHGV-0114224_19 | PHROG | phrog_22135 | NA | unknown function |
| UHGV-0114224_19 | Structural annotation | PF17212 | NA | NA |
| UHGV-0114224_20 | Structural annotation | PF17994 | NA | NA |
| UHGV-0114224_21 | PHROG | phrog_819 | tail protein | tail |
| UHGV-0114224_21 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | Collagen |
| UHGV-0114224_23 | PHROG | phrog_28898 | NA | unknown function |
| UHGV-0114224_23 | eggNOG-mapper | 411901.BACCAC_01110 | NA | NA |
| UHGV-0114224_25 | PHROG | phrog_38431 | NA | unknown function |
| UHGV-0114224_25 | UniRef90 | UniRef90_R5U340 | Conserved domain protein | NA |
| UHGV-0114224_25 | eggNOG-mapper | 762968.HMPREF9441_00551 | NA | NA |
| UHGV-0114224_26 | PHROG | phrog_14770 | NA | unknown function |
| UHGV-0114224_26 | UniRef90 | UniRef90_A0A415VE78 | Helicase ATP-binding domain-containing protein | NA |
| UHGV-0114224_26 | eggNOG-mapper | 1121098.HMPREF1534_01128 | CRISPR-associated helicase, Cas3 | NA |
| UHGV-0114224_26 | Pfam | PF18763 | ddrB-like ParB superfamily domain | ddrB-ParB |
| UHGV-0114224_26 | Pfam | PF13872 | P-loop containing NTP hydrolase pore-1 | AAA_34 |
| UHGV-0114224_26 | Pfam | PF13871 | C-terminal domain on Strawberry notch homologue | Helicase_C_4 |
| UHGV-0114224_26 | Pfam | PF18857 | Large polyvalent protein associated domain 38 | LPD38 |
| UHGV-0114224_26 | COG | COG0454 | N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) | NA |
| UHGV-0114224_30 | eggNOG-mapper | 1121098.HMPREF1534_01130 | NA | NA |
| UHGV-0114224_31 | eggNOG-mapper | 619693.HMPREF6745_1672 | NA | NA |
| UHGV-0114224_32 | PHROG | phrog_1373 | transcriptional regulator | transcription regulation |
| UHGV-0114224_32 | UniRef90 | UniRef90_A0A3R6LFQ0 | XRE family transcriptional regulator | NA |
| UHGV-0114224_32 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0114224_32 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0114224_32 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0114224_41 | Structural annotation | PF18300 | NA | NA |
| UHGV-0114224_45 | PHROG | phrog_98 | NA | unknown function |
| UHGV-0114224_45 | UniRef90 | UniRef90_K1SIW5 | YopX domain-containing protein | NA |
| UHGV-0114224_45 | eggNOG-mapper | 1450694.BTS2_0501 | YopX protein | NA |
| UHGV-0114224_45 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-0114224_45 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-0114224_47 | Structural annotation | PF10623 | NA | NA |
| UHGV-0114224_51 | PHROG | phrog_2118 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0114224_51 | UniRef90 | UniRef90_A0A3E5E2Y4 | HNH endonuclease | NA |
| UHGV-0114224_51 | eggNOG-mapper | 610130.Closa_0730 | HNH endonuclease | NA |
| UHGV-0114224_51 | Pfam | PF01844 | HNH endonuclease | HNH |
| UHGV-0114224_51 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0114224_51 | Structural annotation | NF040563 | NA | NA |
| UHGV-0114224_52 | Structural annotation | TIGR00739 | NA | NA |
| UHGV-0114224_53 | PHROG | phrog_625 | NA | unknown function |
| UHGV-0114224_53 | UniRef90 | UniRef90_A0A3E5E2G2 | ASCH domain-containing protein | NA |
| UHGV-0114224_53 | eggNOG-mapper | 1327970.R9ZXS4_9CAUD | NA | NA |
| UHGV-0114224_53 | Structural annotation | PF12961 | NA | NA |
| UHGV-0114224_54 | Structural annotation | PF01775, MF_00273, NF001981, COG2157 | NA | NA |
| UHGV-0114224_55 | PHROG | phrog_8684 | NA | unknown function |
| UHGV-0114224_55 | UniRef90 | UniRef90_UPI001F350C07 | YopX family protein | NA |
| UHGV-0114224_55 | eggNOG-mapper | 742735.HMPREF9467_00920 | YopX protein | NA |
| UHGV-0114224_55 | Pfam | PF09643 | YopX protein | YopX |
| UHGV-0114224_55 | Structural annotation | PF09643, TIGR01671 | NA | NA |
| UHGV-0114224_57 | Structural annotation | PF04480, NF007294, COG3727 | NA | NA |
| UHGV-0114224_58 | Structural annotation | PF04492 | NA | NA |
| UHGV-0114224_59 | KOfam | K04763 | xerD; integrase/recombinase XerD | NA |
| UHGV-0114224_59 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0114224_59 | UniRef90 | UniRef90_A0A3E5E8Z5 | Site-specific integrase | NA |
| UHGV-0114224_59 | eggNOG-mapper | 742727.HMPREF9447_04802 | Arm DNA-binding domain | NA |
| UHGV-0114224_59 | Pfam | PF17293 | Arm DNA-binding domain | Arm-DNA-bind_5 |
| UHGV-0114224_59 | Pfam | PF13102 | Phage integrase SAM-like domain | Phage_int_SAM_5 |
| UHGV-0114224_59 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0114224_59 | COG | COG4974 | Site-specific recombinase XerD | NA |
| UHGV-0114224_59 | Structural annotation | PF00589, PF17293, PF13102, MF_01808, TIGR02224, COG4974 | NA | NA |
| UHGV-0114224_60 | UniRef90 | UniRef90_A0A3R5ZKQ5 | XRE family transcriptional regulator | NA |
| UHGV-0114224_60 | eggNOG-mapper | 886379.AEWI01000013_gene2144 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0114224_60 | COG | COG3093 | Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain | NA |
| UHGV-0114224_60 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0114224_61 | PHROG | phrog_16858 | NA | unknown function |
| UHGV-0114224_61 | UniRef90 | UniRef90_A0A3D6B2E4 | ArsR family transcriptional regulator | NA |
| UHGV-0114224_61 | Structural annotation | PF08587 | NA | NA |
| UHGV-0114224_62 | PHROG | phrog_5034 | NinG/ Rap DNA junction specific endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0114224_62 | UniRef90 | UniRef90_A0A646FV86 | Recombinase | NA |
| UHGV-0114224_62 | eggNOG-mapper | 585502.HMPREF0645_2608 | NA | NA |
| UHGV-0114224_62 | Pfam | PF05766 | Bacteriophage Lambda NinG protein | NinG |
| UHGV-0114224_62 | COG | COG1403 | 5-methylcytosine-specific restriction endonuclease McrA | NA |
| UHGV-0114224_62 | Structural annotation | PF05766 | NA | NA |
| UHGV-0114224_63 | PHROG | phrog_59 | HNH endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0114224_63 | UniRef90 | UniRef90_UPI001897E143 | NUMOD4 domain-containing protein | NA |
| UHGV-0114224_63 | eggNOG-mapper | 1345695.CLSA_c30140 | NUMOD4 motif | NA |
| UHGV-0114224_63 | PADLOC | HEase_00016 | homing endonuclease | RM |
| UHGV-0114224_63 | Pfam | PF07463 | NUMOD4 motif | NUMOD4 |
| UHGV-0114224_63 | Pfam | PF13384 | Homeodomain-like domain | HTH_23 |
| UHGV-0114224_64 | KOfam | K01520 | dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23] | NA |
| UHGV-0114224_64 | PHROG | phrog_135 | dUTPase | DNA, RNA and nucleotide metabolism |
| UHGV-0114224_64 | UniRef90 | UniRef90_A0A3E5E957 | dUTPase domain-containing protein | NA |
| UHGV-0114224_64 | eggNOG-mapper | 1122128.AUEE01000007_gene1660 | This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | NA |
| UHGV-0114224_64 | Pfam | PF00692 | dUTPase | dUTPase |
| UHGV-0114224_64 | COG | COG0756 | dUTP pyrophosphatase (dUTPase) | NA |
| UHGV-0114224_64 | Structural annotation | PF00692, MF_00116, TIGR00576, COG0756 | NA | NA |
| UHGV-0114224_66 | KOfam | K19171 | dndD; DNA sulfur modification protein DndD | NA |
| UHGV-0114224_66 | PHROG | phrog_77 | SbcC-like subunit of palindrome specific endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0114224_66 | UniRef90 | UniRef90_A0A646FTS8 | AAA family ATPase | NA |
| UHGV-0114224_66 | eggNOG-mapper | 1392486.JIAF01000004_gene2636 | AAA domain | NA |
| UHGV-0114224_66 | Pfam | PF13476 | AAA domain | AAA_23 |
| UHGV-0114224_66 | COG | COG1196 | Chromosome segregation ATPase Smc | NA |
| UHGV-0114224_66 | Structural annotation | PF02463, MF_00449, NF041034, COG0419 | NA | NA |
| UHGV-0114224_67 | Structural annotation | PF18300, COG5475 | NA | NA |
| UHGV-0114224_68 | KOfam | K07455 | recT; recombination protein RecT | NA |
| UHGV-0114224_68 | PHROG | phrog_148 | RecT-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0114224_68 | UniRef90 | UniRef90_A0A3R6HTW1 | Recombinase | NA |
| UHGV-0114224_68 | eggNOG-mapper | 619693.HMPREF6745_2490 | Recombinase, phage RecT family | NA |
| UHGV-0114224_68 | Pfam | PF03837 | RecT family | RecT |
| UHGV-0114224_68 | NCBIFam | TIGR00616.1 | recombinase, phage RecT family | NA |
| UHGV-0114224_68 | COG | COG3723 | Recombinational DNA repair protein RecT | NA |
| UHGV-0114224_68 | Structural annotation | PF03837, TIGR00616, COG3723 | NA | NA |
| UHGV-0114224_69 | PHROG | phrog_872 | NA | unknown function |
| UHGV-0114224_69 | UniRef90 | UniRef90_A0A412HHI1 | NA | NA |
| UHGV-0114224_69 | eggNOG-mapper | 1122971.BAME01000039_gene3564 | NA | NA |
| UHGV-0114224_69 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-0114224_69 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-0114224_69 | Structural annotation | PF11195 | NA | NA |
| UHGV-0114224_70 | PHROG | phrog_392 | metal-dependent hydrolase | other |
| UHGV-0114224_70 | UniRef90 | UniRef90_A0A3R6J4F2 | MBL fold metallo-hydrolase | NA |
| UHGV-0114224_70 | eggNOG-mapper | 86416.Clopa_2515 | Metallo-beta-lactamase superfamily | NA |
| UHGV-0114224_70 | COG | COG1235 | Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase | NA |
| UHGV-0114224_70 | Structural annotation | PF12706, MF_00457, NF041851, COG2220 | NA | NA |
| UHGV-0114224_71 | eggNOG-mapper | 1347393.HG726021_gene517 | NA | NA |
| UHGV-0114224_71 | Structural annotation | PF05772, NF007281 | NA | NA |
| UHGV-0114224_72 | PHROG | phrog_270 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0114224_72 | eggNOG-mapper | 629265.PMA4326_09935 | NA | NA |
| UHGV-0114224_72 | COG | COG3756 | NA | NA |
| UHGV-0114224_73 | Structural annotation | PF20338 | NA | NA |
| UHGV-0114224_80 | Structural annotation | PF10400, COG5570 | NA | NA |
| UHGV-0114224_81 | UniRef90 | UniRef90_A0A3E5E936 | NA | NA |
| UHGV-0114224_81 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0114224_81 | Structural annotation | PF07875, TIGR02501 | NA | NA |