| UHGV-0114819_1 | PHROG | phrog_4433 | NA | unknown function |
| UHGV-0114819_1 | eggNOG-mapper | 33035.JPJF01000122_gene2458 | regulation of DNA-templated transcription, elongation | NA |
| UHGV-0114819_1 | COG | COG5164 | Transcription elongation factor SPT5 | NA |
| UHGV-0114819_2 | PHROG | phrog_10469 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0114819_2 | UniRef90 | UniRef90_A0A174WT25 | Replication initiator A domain-containing protein | NA |
| UHGV-0114819_2 | eggNOG-mapper | 742733.HMPREF9469_01845 | NA | NA |
| UHGV-0114819_2 | Structural annotation | PF07106, MF_01177, NF041413, COG3373 | NA | NA |
| UHGV-0114819_3 | KOfam | K01160 | rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10] | NA |
| UHGV-0114819_3 | PHROG | phrog_1682 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0114819_3 | UniRef90 | UniRef90_A0A1C5MBR6 | Endodeoxyribonuclease RusA | NA |
| UHGV-0114819_3 | eggNOG-mapper | 1235790.C805_00029 | Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC | NA |
| UHGV-0114819_3 | COG | COG4570 | Holliday junction resolvase RusA (prophage-encoded endonuclease) | NA |
| UHGV-0114819_3 | Structural annotation | PF19595, NF007305, COG4570 | NA | NA |
| UHGV-0114819_5 | PHROG | phrog_72 | NinB/ Orf homologous recombination mediator | DNA, RNA and nucleotide metabolism |
| UHGV-0114819_5 | UniRef90 | UniRef90_A0A285PU94 | Recombinase NinB | NA |
| UHGV-0114819_5 | eggNOG-mapper | 411490.ANACAC_00804 | NA | NA |
| UHGV-0114819_5 | Structural annotation | PF05772, NF007281 | NA | NA |
| UHGV-0114819_6 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0114819_6 | UniRef90 | UniRef90_UPI001EDDFED5 | ERF family protein | NA |
| UHGV-0114819_6 | eggNOG-mapper | 386415.NT01CX_2192 | ERF superfamily | NA |
| UHGV-0114819_6 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-0114819_6 | Structural annotation | PF04404, TIGR00607, COG4712 | NA | NA |
| UHGV-0114819_7 | PHROG | phrog_674 | NA | unknown function |
| UHGV-0114819_7 | UniRef90 | UniRef90_A0A415UM66 | NA | NA |
| UHGV-0114819_7 | eggNOG-mapper | 1298920.KI911353_gene4871 | NA | NA |
| UHGV-0114819_7 | Pfam | PF07083 | NA | DUF1351 |
| UHGV-0114819_7 | Structural annotation | PF07083 | NA | NA |
| UHGV-0114819_9 | Structural annotation | PF17981, COG4847 | NA | NA |
| UHGV-0114819_11 | eggNOG-mapper | 760568.Desku_0919 | NA | NA |
| UHGV-0114819_16 | Structural annotation | PF07378, MF_00783, COG5443 | NA | NA |
| UHGV-0114819_18 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-0114819_18 | PHROG | phrog_2104 | NA | unknown function |
| UHGV-0114819_18 | UniRef90 | UniRef90_C0CQZ3 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0114819_18 | eggNOG-mapper | 1235801.C822_00106 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0114819_18 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0114819_18 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0114819_18 | Structural annotation | PF01381, NF041951, COG1476 | NA | NA |
| UHGV-0114819_19 | PHROG | phrog_2967 | transcriptional regulator | transcription regulation |
| UHGV-0114819_19 | UniRef90 | UniRef90_A0A416SLU4 | XRE family transcriptional regulator | NA |
| UHGV-0114819_19 | eggNOG-mapper | 476272.RUMHYD_03305 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-0114819_19 | Pfam | PF13560 | Helix-turn-helix domain | HTH_31 |
| UHGV-0114819_19 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0114819_19 | Structural annotation | PF01381, MF_00535, NF041951, COG3655 | NA | NA |
| UHGV-0114819_22 | PHROG | phrog_4 | transcriptional repressor | transcription regulation |
| UHGV-0114819_22 | UniRef90 | UniRef90_B0G1X6 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0114819_22 | eggNOG-mapper | 742765.HMPREF9457_02739 | NA | NA |
| UHGV-0114819_22 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0114819_22 | Pfam | PF00717 | Peptidase S24-like | Peptidase_S24 |
| UHGV-0114819_22 | Structural annotation | PF13560, NF041951, COG1396 | NA | NA |
| UHGV-0114819_23 | PHROG | phrog_10292 | NA | unknown function |
| UHGV-0114819_23 | UniRef90 | UniRef90_A0A173R9S2 | TM2 domain | NA |
| UHGV-0114819_23 | eggNOG-mapper | 1499689.CCNN01000007_gene1692 | TM2 domain | NA |
| UHGV-0114819_23 | Pfam | PF05154 | TM2 domain | TM2 |
| UHGV-0114819_23 | COG | COG2314 | NA | NA |
| UHGV-0114819_23 | Structural annotation | PF05154, PF12773, MF_00788, NF003161 | NA | NA |
| UHGV-0114819_25 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-0114819_25 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-0114819_25 | UniRef90 | UniRef90_A0A174GRH8 | Autolytic lysozyme | NA |
| UHGV-0114819_25 | eggNOG-mapper | 33035.JPJF01000043_gene994 | Glycosyl hydrolases family 25 | NA |
| UHGV-0114819_25 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-0114819_25 | COG | COG3757 | Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family | NA |
| UHGV-0114819_25 | Structural annotation | PF01183, PF01471, COG3757 | NA | NA |
| UHGV-0114819_26 | Structural annotation | PF13384, NF001074, COG3677 | NA | NA |
| UHGV-0114819_28 | UniRef90 | UniRef90_UPI001C0EBDDC | pyocin knob domain-containing protein | NA |
| UHGV-0114819_29 | PHROG | phrog_18444 | NA | unknown function |
| UHGV-0114819_29 | UniRef90 | UniRef90_UPI00156E9A45 | peptide chain release factor 2 | NA |
| UHGV-0114819_30 | PHROG | phrog_6616 | tail protein | tail |
| UHGV-0114819_30 | UniRef90 | UniRef90_UPI0015714EA8 | tail fiber domain-containing protein | NA |
| UHGV-0114819_30 | eggNOG-mapper | 1121100.JCM6294_1111 | Phage minor structural protein | NA |
| UHGV-0114819_30 | COG | COG4926 | Phage-related protein | NA |
| UHGV-0114819_30 | Structural annotation | PF05113, NF033848, COG3500 | NA | NA |
| UHGV-0114819_31 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-0114819_31 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-0114819_32 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-0114819_32 | UniRef90 | UniRef90_A0A173R880 | Phage-related protein | NA |
| UHGV-0114819_32 | eggNOG-mapper | 476272.RUMHYD_01785 | phage tail tape measure protein | NA |
| UHGV-0114819_32 | COG | COG1511 | NA | NA |
| UHGV-0114819_33 | PHROG | phrog_706 | NA | unknown function |
| UHGV-0114819_33 | UniRef90 | UniRef90_UPI00156F9D1C | Gp15 family bacteriophage protein | NA |
| UHGV-0114819_33 | eggNOG-mapper | 411459.RUMOBE_01383 | Bacteriophage Gp15 protein | NA |
| UHGV-0114819_33 | Pfam | PF06854 | Bacteriophage Gp15 protein | Phage_Gp15 |
| UHGV-0114819_33 | Structural annotation | PF06854 | NA | NA |
| UHGV-0114819_34 | PHROG | phrog_11299 | NA | unknown function |
| UHGV-0114819_34 | eggNOG-mapper | 33035.JPJF01000106_gene3125 | NA | NA |
| UHGV-0114819_34 | Structural annotation | PF10666 | NA | NA |
| UHGV-0114819_35 | PHROG | phrog_3099 | NA | unknown function |
| UHGV-0114819_35 | eggNOG-mapper | 476272.RUMHYD_01782 | NA | NA |
| UHGV-0114819_35 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-0114819_36 | PHROG | phrog_3266 | tail completion | connector |
| UHGV-0114819_36 | eggNOG-mapper | 476272.RUMHYD_01781 | NA | NA |
| UHGV-0114819_36 | Structural annotation | PF12691 | NA | NA |
| UHGV-0114819_37 | PHROG | phrog_556 | minor head protein | head and packaging |
| UHGV-0114819_37 | UniRef90 | UniRef90_UPI0008B4CFF0 | minor capsid protein | NA |
| UHGV-0114819_37 | eggNOG-mapper | 476272.RUMHYD_01780 | NA | NA |
| UHGV-0114819_37 | Pfam | PF11114 | Minor capsid protein | Minor_capsid_2 |
| UHGV-0114819_37 | Structural annotation | PF11114 | NA | NA |
| UHGV-0114819_38 | PHROG | phrog_3366 | NA | unknown function |
| UHGV-0114819_38 | eggNOG-mapper | 476272.RUMHYD_01779 | NA | NA |
| UHGV-0114819_38 | Structural annotation | PF20536, COG5614 | NA | NA |
| UHGV-0114819_39 | PHROG | phrog_541 | head-tail adaptor | connector |
| UHGV-0114819_39 | eggNOG-mapper | 476272.RUMHYD_01778 | NA | NA |
| UHGV-0114819_41 | UniRef90 | UniRef90_A0A0M2NI16 | S-l_SbsC_C domain-containing protein | NA |
| UHGV-0114819_41 | Structural annotation | PF11651, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-0114819_42 | PHROG | phrog_194 | head scaffolding protein | head and packaging |
| UHGV-0114819_42 | UniRef90 | UniRef90_UPI001C1258D3 | phage scaffolding protein | NA |
| UHGV-0114819_42 | eggNOG-mapper | 397290.C810_05223 | Phage minor structural protein GP20 | NA |
| UHGV-0114819_42 | Pfam | PF06810 | Phage minor structural protein GP20 | Phage_GP20 |
| UHGV-0114819_42 | Structural annotation | PF06810 | NA | NA |
| UHGV-0114819_44 | Structural annotation | PF00210, MF_01441, NF011597, COG1528 | NA | NA |
| UHGV-0114819_45 | PHROG | phrog_20016 | NA | unknown function |
| UHGV-0114819_45 | UniRef90 | UniRef90_A0A316MV88 | BclA_C domain-containing protein | NA |
| UHGV-0114819_45 | eggNOG-mapper | 1226322.HMPREF1545_00077 | NA | NA |
| UHGV-0114819_45 | Structural annotation | PF18573, NF033147 | NA | NA |
| UHGV-0114819_47 | eggNOG-mapper | 476272.RUMHYD_01770 | NA | NA |
| UHGV-0114819_49 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-0114819_49 | eggNOG-mapper | 1235790.C805_00058 | NA | NA |
| UHGV-0114819_50 | PHROG | phrog_2428 | NA | unknown function |
| UHGV-0114819_50 | UniRef90 | UniRef90_A0A396QA65 | ABC transporter ATPase | NA |
| UHGV-0114819_50 | eggNOG-mapper | 632245.CLP_1645 | NA | NA |
| UHGV-0114819_50 | dbAPIS | APIS024 | Tad1 proteins are not an enzymes, but are 'sponges' that bind and sequester the immune signaling molecule (cyclic ADP-ribose or gcADPR) produced by TIR-domain proteins, thus decoupling phage sensing from immune effector activation and rendering Thoeris inactive. | NA |
| UHGV-0114819_51 | UniRef90 | UniRef90_UPI001105DD43 | NA | NA |
| UHGV-0114819_51 | eggNOG-mapper | 97139.C824_02654 | NA | NA |
| UHGV-0114819_51 | Pfam | PF07866 | NA | DUF1653 |
| UHGV-0114819_51 | COG | COG4728 | NA | NA |
| UHGV-0114819_51 | Structural annotation | PF07866, COG4728 | NA | NA |
| UHGV-0114819_52 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-0114819_52 | eggNOG-mapper | 1385512.N784_13055 | NA | NA |
| UHGV-0114819_52 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-0114819_52 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-0114819_52 | Structural annotation | PF11195, PF04085 | NA | NA |
| UHGV-0114819_53 | Structural annotation | PF16170 | NA | NA |
| UHGV-0114819_54 | UniRef90 | UniRef90_A0A843HPX3 | Sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-0114819_54 | eggNOG-mapper | 1235790.C805_00057 | NA | NA |
| UHGV-0114819_54 | Structural annotation | PF13404, TIGR01636 | NA | NA |
| UHGV-0114819_55 | UniRef90 | UniRef90_A0A416S3A4 | CTP synthase | NA |
| UHGV-0114819_55 | eggNOG-mapper | 476272.RUMHYD_01766 | NA | NA |
| UHGV-0114819_56 | PHROG | phrog_28328 | NA | unknown function |
| UHGV-0114819_56 | eggNOG-mapper | 552398.HMPREF0866_03119 | NA | NA |
| UHGV-0114819_57 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-0114819_57 | UniRef90 | UniRef90_A0A414QMN0 | Phage capsid protein | NA |
| UHGV-0114819_57 | eggNOG-mapper | 476272.RUMHYD_01761 | Phage minor capsid protein 2 | NA |
| UHGV-0114819_57 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-0114819_57 | COG | COG2369 | NA | NA |
| UHGV-0114819_57 | Structural annotation | PF06152 | NA | NA |
| UHGV-0114819_58 | PHROG | phrog_443 | holin | lysis |
| UHGV-0114819_58 | UniRef90 | UniRef90_UPI000E5CA950 | holin | NA |
| UHGV-0114819_58 | eggNOG-mapper | 1235802.C823_05612 | Putative lactococcus lactis phage r1t holin | NA |
| UHGV-0114819_58 | Pfam | PF16945 | Putative lactococcus lactis phage r1t holin | Phage_r1t_holin |
| UHGV-0114819_58 | Structural annotation | PF16945 | NA | NA |
| UHGV-0114819_59 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-0114819_59 | UniRef90 | UniRef90_A0A3D2KHB8 | Phage capsid protein | NA |
| UHGV-0114819_59 | eggNOG-mapper | 397290.C810_05196 | phage minor capsid protein | NA |
| UHGV-0114819_59 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-0114819_60 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0114819_60 | PHROG | phrog_10250 | NA | unknown function |
| UHGV-0114819_60 | UniRef90 | UniRef90_A0A373MY72 | PBSX family phage terminase large subunit | NA |
| UHGV-0114819_60 | eggNOG-mapper | 397290.C810_05187 | Phage terminase large subunit | NA |
| UHGV-0114819_60 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-0114819_60 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-0114819_60 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0114819_60 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0114819_61 | KOfam | K07474 | xtmA; phage terminase small subunit | NA |
| UHGV-0114819_61 | PHROG | phrog_51 | terminase small subunit | head and packaging |
| UHGV-0114819_61 | UniRef90 | UniRef90_A0A414QMP8 | Terminase small subunit | NA |
| UHGV-0114819_61 | eggNOG-mapper | 476272.RUMHYD_01754 | Terminase small subunit | NA |
| UHGV-0114819_61 | Pfam | PF03592 | Terminase small subunit | Terminase_2 |
| UHGV-0114819_61 | COG | COG3728 | Phage terminase, small subunit | NA |
| UHGV-0114819_61 | Structural annotation | PF03592, COG3728 | NA | NA |
| UHGV-0114819_63 | PHROG | phrog_33130 | NA | unknown function |
| UHGV-0114819_63 | UniRef90 | UniRef90_A0A3B9CD52 | S1-like domain-containing protein | NA |
| UHGV-0114819_63 | Structural annotation | PF10922, MF_00839 | NA | NA |
| UHGV-0114819_65 | PHROG | phrog_8680 | NA | unknown function |
| UHGV-0114819_65 | UniRef90 | UniRef90_A0A3R6D7I3 | NA | NA |
| UHGV-0114819_65 | eggNOG-mapper | 411470.RUMGNA_02208 | NA | NA |
| UHGV-0114819_65 | Pfam | PF14386 | NA | DUF4417 |
| UHGV-0114819_65 | Structural annotation | PF14386 | NA | NA |
| UHGV-0114819_66 | KOfam | K06400 | spoIVCA; site-specific DNA recombinase | NA |
| UHGV-0114819_66 | PHROG | phrog_95 | integrase | integration and excision |
| UHGV-0114819_66 | UniRef90 | UniRef90_E9SBY7 | Resolvase, N-terminal domain protein | NA |
| UHGV-0114819_66 | eggNOG-mapper | 246199.CUS_6803 | NA | NA |
| UHGV-0114819_66 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-0114819_66 | Pfam | PF07508 | Recombinase | Recombinase |
| UHGV-0114819_66 | Pfam | PF13408 | Recombinase zinc beta ribbon domain | Zn_ribbon_recom |
| UHGV-0114819_66 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-0114819_66 | Structural annotation | PF00239, PF07508, NF041201, COG1961 | NA | NA |
| UHGV-0114819_68 | eggNOG-mapper | 476272.RUMHYD_01751 | NA | NA |
| UHGV-0114819_70 | PHROG | phrog_22292 | NA | unknown function |
| UHGV-0114819_71 | PHROG | phrog_20593 | NA | unknown function |
| UHGV-0114819_72 | UniRef90 | UniRef90_UPI00040CBFF3 | NA | NA |
| UHGV-0114819_72 | eggNOG-mapper | 665950.HMPREF1025_02540 | NA | NA |
| UHGV-0114819_74 | PHROG | phrog_31463 | NA | unknown function |
| UHGV-0114819_74 | UniRef90 | UniRef90_UPI001160B515 | LemA family protein | NA |
| UHGV-0114819_75 | PHROG | phrog_25456 | NA | unknown function |
| UHGV-0114819_76 | eggNOG-mapper | 457412.RSAG_01159 | NA | NA |
| UHGV-0114819_79 | eggNOG-mapper | 1415774.U728_858 | NA | NA |
| UHGV-0114819_82 | Structural annotation | PF20020 | NA | NA |
| UHGV-0114819_84 | Structural annotation | PF18358 | NA | NA |
| UHGV-0114819_88 | UniRef90 | UniRef90_UPI0018979093 | NA | NA |
| UHGV-0114819_88 | eggNOG-mapper | 411460.RUMTOR_01556 | NA | NA |
| UHGV-0114819_88 | Pfam | PF14199 | NA | DUF4317 |
| UHGV-0114819_88 | Structural annotation | PF14199, MF_00730, NF001557, COG3081 | NA | NA |
| UHGV-0114819_89 | PHROG | phrog_4433 | NA | unknown function |
| UHGV-0114819_89 | eggNOG-mapper | 394503.Ccel_3068 | regulation of DNA-templated transcription, elongation | NA |
| UHGV-0114819_89 | COG | COG5164 | Transcription elongation factor SPT5 | NA |