| UHGV-1368904_1 | Structural annotation | PF21138, NF009630, COG2375 | NA | NA |
| UHGV-1368904_2 | PHROG | phrog_2002 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1368904_2 | Structural annotation | PF01870, MF_01490, NF040854, COG1591 | NA | NA |
| UHGV-1368904_8 | PHROG | phrog_159 | RuvC-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-1368904_8 | Structural annotation | PF02075, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-1368904_9 | PHROG | phrog_799 | DNA methyltransferase | other |
| UHGV-1368904_9 | UniRef90 | UniRef90_UPI00096A7820 | sugar-phospahte nucleotidyltransferase | NA |
| UHGV-1368904_9 | eggNOG-mapper | 1235793.C809_00185 | NA | NA |
| UHGV-1368904_9 | Structural annotation | PF13651, MF_00607, NF000077, COG0286 | NA | NA |
| UHGV-1368904_11 | PHROG | phrog_1706 | CRISPR/Cas system associated | DNA, RNA and nucleotide metabolism |
| UHGV-1368904_11 | COG | COG1468 | CRISPR/Cas system-associated exonuclease Cas4, RecB family | NA |
| UHGV-1368904_11 | Structural annotation | PF01930, MF_03030, TIGR00372, COG5377 | NA | NA |
| UHGV-1368904_17 | KOfam | K03553 | recA; recombination protein RecA | NA |
| UHGV-1368904_17 | PHROG | phrog_97 | UvsX-like recombinase | other |
| UHGV-1368904_17 | UniRef90 | UniRef90_A0A843GSV7 | RECA_3 domain-containing protein | NA |
| UHGV-1368904_17 | eggNOG-mapper | 585506.HMPREF0877_1669 | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage | NA |
| UHGV-1368904_17 | Pfam | PF00154 | recA bacterial DNA recombination protein | RecA |
| UHGV-1368904_17 | COG | COG0468 | RecA/RadA recombinase | NA |
| UHGV-1368904_17 | Structural annotation | PF00154, MF_00268, TIGR02012, COG0468 | NA | NA |
| UHGV-1368904_19 | UniRef90 | UniRef90_A0A1T4M3S7 | Pyrimidine dimer DNA glycosylase /DNA-(Apurinic or apyrimidinic site) lyase | NA |
| UHGV-1368904_19 | eggNOG-mapper | 272563.CD630_17570 | Pyrimidine dimer DNA glycosylase | NA |
| UHGV-1368904_19 | Pfam | PF03013 | Pyrimidine dimer DNA glycosylase | Pyr_excise |
| UHGV-1368904_19 | Structural annotation | PF03013, TIGR02328 | NA | NA |
| UHGV-1368904_22 | KOfam | K01495 | GCH1, folE; GTP cyclohydrolase IA [EC:3.5.4.16] | NA |
| UHGV-1368904_22 | PHROG | phrog_2197 | GTP cyclohydrolase | other |
| UHGV-1368904_22 | UniRef90 | UniRef90_R7N4B8 | GTP cyclohydrolase 1 | NA |
| UHGV-1368904_22 | eggNOG-mapper | 1230342.CTM_10431 | GTP cyclohydrolase | NA |
| UHGV-1368904_22 | Pfam | PF01227 | GTP cyclohydrolase I | GTP_cyclohydroI |
| UHGV-1368904_22 | NCBIFam | NF006826.0 | GTP cyclohydrolase I FolE | NA |
| UHGV-1368904_22 | COG | COG0302 | GTP cyclohydrolase I | NA |
| UHGV-1368904_22 | HAMAP | MF_00223 | GTP cyclohydrolase 1 [folE] | NA |
| UHGV-1368904_22 | Structural annotation | PF01227, MF_00223, NF006826, COG0302 | NA | NA |
| UHGV-1368904_23 | KOfam | K10026 | queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] | NA |
| UHGV-1368904_23 | PHROG | phrog_2076 | QueE-like radical SAM domain | moron, auxiliary metabolic gene and host takeover |
| UHGV-1368904_23 | UniRef90 | UniRef90_A4XFS3 | 7-carboxy-7-deazaguanine synthase | NA |
| UHGV-1368904_23 | eggNOG-mapper | 351627.Csac_0105 | Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds | NA |
| UHGV-1368904_23 | PADLOC | pVip-lone | Viperins not associated with kinases | Viperin |
| UHGV-1368904_23 | Pfam | PF04055 | Radical SAM superfamily | Radical_SAM |
| UHGV-1368904_23 | COG | COG0602 | Organic radical activating enzyme NrdG/QueE | NA |
| UHGV-1368904_23 | HAMAP | MF_00917 | 7-carboxy-7-deazaguanine synthase [queE] | NA |
| UHGV-1368904_23 | Structural annotation | PF04055, MF_00917, TIGR04508, COG0602 | NA | NA |
| UHGV-1368904_24 | KOfam | K01737 | queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] | NA |
| UHGV-1368904_24 | PHROG | phrog_2389 | QueD-like 6-pyruvoyl-tetrahydropterin synthase | moron, auxiliary metabolic gene and host takeover |
| UHGV-1368904_24 | UniRef90 | UniRef90_A0A2M9A8G5 | 6-carboxy-5,6,7,8-tetrahydropterin synthase | NA |
| UHGV-1368904_24 | eggNOG-mapper | 59374.Fisuc_2952 | synthase | NA |
| UHGV-1368904_24 | Pfam | PF01242 | 6-pyruvoyl tetrahydropterin synthase | PTPS |
| UHGV-1368904_24 | NCBIFam | TIGR03367.1 | 6-carboxytetrahydropterin synthase QueD | NA |
| UHGV-1368904_24 | COG | COG0720 | 6-pyruvoyl-tetrahydropterin synthase | NA |
| UHGV-1368904_24 | Structural annotation | PF01242, TIGR00039, COG0720 | NA | NA |
| UHGV-1368904_25 | PHROG | phrog_20335 | NA | unknown function |
| UHGV-1368904_25 | Structural annotation | PF01702, MF_01634, TIGR00432, COG0343 | NA | NA |
| UHGV-1368904_26 | PHROG | phrog_761 | thymidylate kinase | other |
| UHGV-1368904_26 | Pfam | PF01712 | Deoxynucleoside kinase | dNK |
| UHGV-1368904_27 | PHROG | phrog_229 | MazG-like pyrophosphatase | other |
| UHGV-1368904_27 | UniRef90 | UniRef90_UPI001788C72C | nucleoside triphosphate pyrophosphohydrolase family protein | NA |
| UHGV-1368904_27 | eggNOG-mapper | 935948.KE386495_gene1195 | MazG nucleotide pyrophosphohydrolase | NA |
| UHGV-1368904_27 | Pfam | PF03819 | MazG nucleotide pyrophosphohydrolase domain | MazG |
| UHGV-1368904_27 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-1368904_27 | Structural annotation | PF03819, MF_01020, NF001613, COG0140 | NA | NA |
| UHGV-1368904_28 | PHROG | phrog_17812 | NA | unknown function |
| UHGV-1368904_28 | eggNOG-mapper | 419610.Mext_0158 | NA | NA |
| UHGV-1368904_28 | Structural annotation | PF01242, TIGR00039, COG0720 | NA | NA |
| UHGV-1368904_29 | KOfam | K02337 | dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] | NA |
| UHGV-1368904_29 | PHROG | phrog_405 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-1368904_29 | UniRef90 | UniRef90_A0A843GPT9 | DNA-directed DNA polymerase | NA |
| UHGV-1368904_29 | eggNOG-mapper | 436114.SYO3AOP1_0632 | TIGRFAM DNA polymerase III, alpha subunit | NA |
| UHGV-1368904_29 | Pfam | PF02811 | PHP domain | PHP |
| UHGV-1368904_29 | Pfam | PF07733 | Bacterial DNA polymerase III alpha NTPase domain | DNA_pol3_alpha |
| UHGV-1368904_29 | Pfam | PF17657 | Bacterial DNA polymerase III alpha subunit finger domain | DNA_pol3_finger |
| UHGV-1368904_29 | Pfam | PF14579 | Helix-hairpin-helix motif | HHH_6 |
| UHGV-1368904_29 | NCBIFam | TIGR00594.1 | DNA polymerase III subunit alpha | NA |
| UHGV-1368904_29 | COG | COG0587 | DNA polymerase III, alpha subunit | NA |
| UHGV-1368904_29 | Structural annotation | PF07733, PF02811, PF17657, PF14579, MF_01902, TIGR00594, COG0587 | NA | NA |
| UHGV-1368904_30 | Structural annotation | PF08804 | NA | NA |
| UHGV-1368904_31 | KOfam | K02316 | dnaG; DNA primase [EC:2.7.7.101] | NA |
| UHGV-1368904_31 | PHROG | phrog_47 | DNA primase | DNA, RNA and nucleotide metabolism |
| UHGV-1368904_31 | UniRef90 | UniRef90_A0A843GN62 | Toprim domain-containing protein | NA |
| UHGV-1368904_31 | eggNOG-mapper | 309807.SRU_0970 | RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication | NA |
| UHGV-1368904_31 | Pfam | PF01807 | CHC2 zinc finger | zf-CHC2 |
| UHGV-1368904_31 | Pfam | PF13155 | Toprim-like | Toprim_2 |
| UHGV-1368904_31 | COG | COG0358 | DNA primase (bacterial type) | NA |
| UHGV-1368904_31 | Structural annotation | PF01807, PF13155, MF_00974, TIGR01391, COG0358 | NA | NA |
| UHGV-1368904_33 | Structural annotation | PF07498, PF09465, MF_00749, NF037951, COG1862 | NA | NA |
| UHGV-1368904_37 | UniRef90 | UniRef90_A0A843GWV6 | Rubrerythrin domain-containing protein | NA |
| UHGV-1368904_37 | Pfam | PF02915 | Rubrerythrin | Rubrerythrin |
| UHGV-1368904_38 | eggNOG-mapper | 1408437.JNJN01000043_gene802 | NA | NA |
| UHGV-1368904_39 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-1368904_39 | eggNOG-mapper | 1408437.JNJN01000043_gene803 | NA | NA |
| UHGV-1368904_41 | PHROG | phrog_21718 | NA | unknown function |
| UHGV-1368904_41 | eggNOG-mapper | 1408437.JNJN01000043_gene805 | NA | NA |
| UHGV-1368904_45 | eggNOG-mapper | 610130.Closa_0760 | NA | NA |
| UHGV-1368904_46 | PHROG | phrog_1220 | head protein | head and packaging |
| UHGV-1368904_46 | eggNOG-mapper | 588581.Cpap_1262 | COG NOG18825 non supervised orthologous group | NA |
| UHGV-1368904_46 | Structural annotation | PF15432, TIGR03711 | NA | NA |
| UHGV-1368904_47 | PHROG | phrog_538 | minor tail protein | tail |
| UHGV-1368904_47 | UniRef90 | UniRef90_UPI000666E2A6 | siphovirus ReqiPepy6 Gp37-like family protein | NA |
| UHGV-1368904_47 | eggNOG-mapper | 768704.Desmer_4453 | Siphovirus ReqiPepy6 Gp37-like protein | NA |
| UHGV-1368904_47 | Pfam | PF14594 | Siphovirus ReqiPepy6 Gp37-like protein | Sipho_Gp37 |
| UHGV-1368904_47 | Structural annotation | PF14594, TIGR01665, COG4926 | NA | NA |
| UHGV-1368904_48 | PHROG | phrog_36410 | NA | unknown function |
| UHGV-1368904_48 | UniRef90 | UniRef90_A0A7X9C3E1 | Phage tail family protein | NA |
| UHGV-1368904_48 | eggNOG-mapper | 431943.CKL_4056 | Phage tail protein | NA |
| UHGV-1368904_48 | Pfam | PF05709 | Phage tail protein RIFT-related domain | Sipho_tail |
| UHGV-1368904_48 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-1368904_48 | Structural annotation | PF20753, PF16774, TIGR01633, COG4722 | NA | NA |
| UHGV-1368904_49 | PHROG | phrog_1533 | tail length tape measure protein | tail |
| UHGV-1368904_49 | eggNOG-mapper | 411459.RUMOBE_01725 | Phage tail tape measure protein, TP901 family | NA |
| UHGV-1368904_49 | Pfam | PF10145 | Phage-related minor tail protein | PhageMin_Tail |
| UHGV-1368904_49 | NCBIFam | TIGR01760.1 | phage tail tape measure protein | NA |
| UHGV-1368904_49 | COG | COG5283 | Phage-related tail protein | NA |
| UHGV-1368904_49 | Structural annotation | PF10145, TIGR01760, COG3941 | NA | NA |
| UHGV-1368904_50 | PHROG | phrog_6541 | NA | unknown function |
| UHGV-1368904_50 | eggNOG-mapper | 1196322.A370_04057 | NA | NA |
| UHGV-1368904_51 | PHROG | phrog_6280 | NA | unknown function |
| UHGV-1368904_51 | UniRef90 | UniRef90_A0A8J6PH67 | Esterase | NA |
| UHGV-1368904_51 | eggNOG-mapper | 445335.CBN_3078 | NA | NA |
| UHGV-1368904_52 | PHROG | phrog_6686 | tail tube protein | tail |
| UHGV-1368904_52 | UniRef90 | UniRef90_A0A1C6KI12 | S-l_SbsC_C domain-containing protein | NA |
| UHGV-1368904_52 | eggNOG-mapper | 871584.D9ZNE2_9CAUD | NA | NA |
| UHGV-1368904_52 | Structural annotation | PF06488, TIGR01603, COG3498 | NA | NA |
| UHGV-1368904_53 | PHROG | phrog_7585 | NA | unknown function |
| UHGV-1368904_53 | eggNOG-mapper | 748727.CLJU_c31260 | NA | NA |
| UHGV-1368904_53 | Structural annotation | PF05657, NF040576, COG3167 | NA | NA |
| UHGV-1368904_54 | eggNOG-mapper | 580331.Thit_1383 | NA | NA |
| UHGV-1368904_54 | Structural annotation | PF04883, TIGR01725 | NA | NA |
| UHGV-1368904_55 | Structural annotation | PF07405, TIGR01563, COG5614 | NA | NA |
| UHGV-1368904_56 | PHROG | phrog_4020 | NA | unknown function |
| UHGV-1368904_56 | eggNOG-mapper | 1443122.Z958_05850 | NA | NA |
| UHGV-1368904_57 | Structural annotation | PF07498 | NA | NA |
| UHGV-1368904_58 | PHROG | phrog_29 | major head protein | head and packaging |
| UHGV-1368904_58 | UniRef90 | UniRef90_A0A843GQH0 | Major capsid protein | NA |
| UHGV-1368904_58 | eggNOG-mapper | 1158612.I580_01912 | Phage major capsid protein E | NA |
| UHGV-1368904_58 | Pfam | PF03864 | Phage major capsid protein E | Phage_cap_E |
| UHGV-1368904_58 | Structural annotation | PF03864, MF_04133, NF041162, COG4653 | NA | NA |
| UHGV-1368904_59 | PHROG | phrog_909 | major head protein | head and packaging |
| UHGV-1368904_59 | eggNOG-mapper | 1158612.I580_01911 | NA | NA |
| UHGV-1368904_59 | Structural annotation | PF02924 | NA | NA |
| UHGV-1368904_60 | PHROG | phrog_2303 | head scaffolding protein | head and packaging |
| UHGV-1368904_60 | eggNOG-mapper | 1121871.AUAT01000035_gene1288 | NA | NA |
| UHGV-1368904_60 | Structural annotation | MF_02110 | NA | NA |
| UHGV-1368904_61 | PHROG | phrog_1315 | NA | unknown function |
| UHGV-1368904_65 | PHROG | phrog_1657 | head morphogenesis | head and packaging |
| UHGV-1368904_65 | UniRef90 | UniRef90_UPI001D0FF452 | ADP-ribosyltransferase | NA |
| UHGV-1368904_65 | eggNOG-mapper | 1582149.A0A0A8WEF5_9CAUD | Phage Mu protein F like protein | NA |
| UHGV-1368904_65 | Structural annotation | PF04233, TIGR01641 | NA | NA |
| UHGV-1368904_66 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-1368904_66 | UniRef90 | UniRef90_A0A843GSM3 | Phage portal protein | NA |
| UHGV-1368904_66 | eggNOG-mapper | 59241.E7DNA2_BPDP1 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-1368904_66 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-1368904_66 | Structural annotation | PF05133, MF_04120, TIGR01538, COG3567 | NA | NA |
| UHGV-1368904_67 | KOfam | K17733 | cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-] | NA |
| UHGV-1368904_67 | PHROG | phrog_2649 | endolysin | lysis |
| UHGV-1368904_67 | UniRef90 | UniRef90_UPI0018972856 | M15 family metallopeptidase | NA |
| UHGV-1368904_67 | eggNOG-mapper | 397290.C810_03258 | D-alanyl-D-alanine carboxypeptidase | NA |
| UHGV-1368904_67 | AcrCatalog | cluster_9940 | NA | NA |
| UHGV-1368904_67 | Pfam | PF13539 | D-alanyl-D-alanine carboxypeptidase | Peptidase_M15_4 |
| UHGV-1368904_67 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-1368904_67 | COG | COG1876 | LD-carboxypeptidase LdcB, LAS superfamily | NA |
| UHGV-1368904_67 | Structural annotation | PF02557, PF18342, MF_01924, NF007557, COG4991, COG2173 | NA | NA |
| UHGV-1368904_68 | PHROG | phrog_443 | holin | lysis |
| UHGV-1368904_68 | UniRef90 | UniRef90_UPI000CF1F0AD | holin | NA |
| UHGV-1368904_68 | eggNOG-mapper | 626523.GCWU000342_01012 | Putative lactococcus lactis phage r1t holin | NA |
| UHGV-1368904_68 | Pfam | PF16945 | Putative lactococcus lactis phage r1t holin | Phage_r1t_holin |
| UHGV-1368904_68 | Structural annotation | PF16945 | NA | NA |
| UHGV-1368904_70 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-1368904_70 | PHROG | phrog_3717 | terminase large subunit | head and packaging |
| UHGV-1368904_70 | UniRef90 | UniRef90_A0A349YI29 | PBSX family phage terminase large subunit | NA |
| UHGV-1368904_70 | eggNOG-mapper | 1443122.Z958_p0035 | Phage terminase, large subunit, PBSX family | NA |
| UHGV-1368904_70 | Pfam | PF04466 | Phage terminase large subunit | Terminase_3 |
| UHGV-1368904_70 | Pfam | PF17288 | Terminase RNAseH like domain | Terminase_3C |
| UHGV-1368904_70 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-1368904_70 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-1368904_70 | Structural annotation | PF04466, PF17288, MF_04145, TIGR01547, COG1783 | NA | NA |
| UHGV-1368904_71 | UniRef90 | UniRef90_A0A285CJV6 | DNA-packaging protein gp3 | NA |
| UHGV-1368904_71 | Structural annotation | PF16677 | NA | NA |
| UHGV-1368904_72 | eggNOG-mapper | 411470.RUMGNA_02035 | NA | NA |
| UHGV-1368904_78 | Structural annotation | PF14084 | NA | NA |
| UHGV-1368904_79 | KOfam | K03469 | rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4] | NA |
| UHGV-1368904_79 | PHROG | phrog_531 | Rnase H | DNA, RNA and nucleotide metabolism |
| UHGV-1368904_79 | UniRef90 | UniRef90_UPI001E2A90F9 | ribonuclease HI | NA |
| UHGV-1368904_79 | eggNOG-mapper | 1408427.JADB01000001_gene439 | Endonuclease that specifically degrades the RNA of RNA- DNA hybrids | NA |
| UHGV-1368904_79 | Pfam | PF00075 | RNase H | RNase_H |
| UHGV-1368904_79 | COG | COG0328 | Ribonuclease HI | NA |
| UHGV-1368904_79 | Structural annotation | PF00075, MF_00042, NF001236, COG0328 | NA | NA |