| UHGV-0180216_2 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0180216_2 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_2 | UniRef90 | UniRef90_A0A564SBR1 | Replicative DNA helicase | NA |
| UHGV-0180216_2 | eggNOG-mapper | 1203606.HMPREF1526_01325 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-0180216_2 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0180216_2 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0180216_2 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0180216_3 | PHROG | phrog_678 | replication initiation O-like | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_3 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-0180216_3 | Structural annotation | PF19808 | NA | NA |
| UHGV-0180216_4 | PHROG | phrog_599 | Lar-like restriction alleviation protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-0180216_4 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-0180216_4 | NCBIFam | TIGR03655.1 | Lar family restriction alleviation protein | NA |
| UHGV-0180216_4 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-0180216_4 | Structural annotation | NF007260 | NA | NA |
| UHGV-0180216_5 | Structural annotation | PF14354, TIGR03655 | NA | NA |
| UHGV-0180216_7 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0180216_8 | Structural annotation | NF041588 | NA | NA |
| UHGV-0180216_14 | UniRef90 | UniRef90_UPI0012DD33A2 | restriction endonuclease subunit M | NA |
| UHGV-0180216_14 | eggNOG-mapper | 596329.HMPREF0631_0252 | restriction endonuclease | NA |
| UHGV-0180216_14 | PADLOC | MTase_II_00176 | Type II methyltransferase | RM |
| UHGV-0180216_14 | COG | COG1002 | Type II restriction/modification system, endonuclease and methylase domains | NA |
| UHGV-0180216_16 | Structural annotation | PF16677 | NA | NA |
| UHGV-0180216_17 | Pfam | PF04448 | NA | DUF551 |
| UHGV-0180216_17 | Structural annotation | NF041588 | NA | NA |
| UHGV-0180216_21 | Structural annotation | PF11998, COG5420 | NA | NA |
| UHGV-0180216_24 | PHROG | phrog_843 | Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_24 | UniRef90 | UniRef90_UPI000C78AB6D | Holliday junction resolvase RecU | NA |
| UHGV-0180216_24 | eggNOG-mapper | 929506.CbC4_1203 | Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation | NA |
| UHGV-0180216_24 | Structural annotation | PF03838, MF_00130, NF002581, COG3331 | NA | NA |
| UHGV-0180216_26 | PHROG | phrog_35094 | NA | unknown function |
| UHGV-0180216_26 | eggNOG-mapper | 457424.BFAG_02409 | NA | NA |
| UHGV-0180216_28 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0180216_28 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0180216_28 | UniRef90 | UniRef90_D4JYK0 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0180216_28 | eggNOG-mapper | 718252.FP2_16350 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-0180216_28 | PADLOC | oMTase_00004 | orphan methyltransferase | RM |
| UHGV-0180216_28 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0180216_28 | NCBIFam | TIGR00675.1 | DNA (cytosine-5-)-methyltransferase | NA |
| UHGV-0180216_28 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0180216_28 | Structural annotation | PF00145, TIGR00675 | NA | NA |
| UHGV-0180216_29 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0180216_29 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_29 | UniRef90 | UniRef90_A0A6N7TNV3 | Single-stranded DNA-binding protein | NA |
| UHGV-0180216_29 | eggNOG-mapper | 748224.HMPREF9436_03359 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-0180216_29 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0180216_29 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0180216_29 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0180216_29 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0180216_29 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0180216_30 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_30 | UniRef90 | UniRef90_E2ZNS9 | Erf family protein | NA |
| UHGV-0180216_30 | eggNOG-mapper | 748224.HMPREF9436_03360 | ERF superfamily | NA |
| UHGV-0180216_30 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-0180216_30 | Structural annotation | PF04404, COG4712 | NA | NA |
| UHGV-0180216_31 | PHROG | phrog_38771 | NA | unknown function |
| UHGV-0180216_32 | Structural annotation | PF14143 | NA | NA |
| UHGV-0180216_33 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0180216_33 | Structural annotation | PF13443, TIGR02684, COG1476 | NA | NA |
| UHGV-0180216_36 | Structural annotation | TIGR03826 | NA | NA |
| UHGV-0180216_38 | Structural annotation | PF10922 | NA | NA |
| UHGV-0180216_39 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0180216_39 | PHROG | phrog_130 | anti-repressor Ant | transcription regulation |
| UHGV-0180216_39 | UniRef90 | UniRef90_K0J5T4 | Bro-N domain-containing protein | NA |
| UHGV-0180216_39 | eggNOG-mapper | 698758.AXY_01910 | Antirepressor | NA |
| UHGV-0180216_39 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-0180216_39 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0180216_39 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-0180216_39 | Structural annotation | PF03374, PF02498, TIGR02681, COG3617, COG3645 | NA | NA |
| UHGV-0180216_40 | UniRef90 | UniRef90_UPI0012AC17D6 | helix-turn-helix domain-containing protein | NA |
| UHGV-0180216_40 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0180216_40 | Structural annotation | PF13560, NF041951, COG1396 | NA | NA |
| UHGV-0180216_41 | UniRef90 | UniRef90_A0A316RBI4 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0180216_41 | eggNOG-mapper | 663278.Ethha_0519 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-0180216_41 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0180216_41 | Structural annotation | PF12844, MF_00535, NF007257, COG1396 | NA | NA |
| UHGV-0180216_45 | UniRef90 | UniRef90_A0A2A7AM70 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0180216_45 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0180216_45 | Structural annotation | PF13560, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0180216_47 | PHROG | phrog_4402 | replication initiation protein | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_47 | UniRef90 | UniRef90_A0A0H5Q331 | Rep_3 domain-containing protein | NA |
| UHGV-0180216_47 | eggNOG-mapper | 999413.HMPREF1094_04438 | Initiator Replication protein | NA |
| UHGV-0180216_47 | Pfam | PF01051 | Initiator Replication protein, WH1 | Rep3_N |
| UHGV-0180216_47 | Pfam | PF21205 | Initiator Rep protein, WH2 | Rep3_C |
| UHGV-0180216_47 | COG | COG5527 | Protein involved in initiation of plasmid replication | NA |
| UHGV-0180216_47 | Structural annotation | PF01051, PF21205, NF038290, COG5527 | NA | NA |
| UHGV-0180216_49 | KOfam | K03496 | parA, soj; chromosome partitioning protein | NA |
| UHGV-0180216_49 | PHROG | phrog_164 | ParA-like partition protein | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_49 | UniRef90 | UniRef90_A0A1C6BS15 | Sporulation initiation inhibitor protein soj | NA |
| UHGV-0180216_49 | eggNOG-mapper | 1408423.JHYA01000021_gene392 | Cellulose biosynthesis protein BcsQ | NA |
| UHGV-0180216_49 | Pfam | PF13614 | AAA domain | AAA_31 |
| UHGV-0180216_49 | COG | COG1192 | ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ | NA |
| UHGV-0180216_49 | Structural annotation | PF13614, MF_00533, NF010443, COG1192 | NA | NA |
| UHGV-0180216_50 | Structural annotation | PF07878 | NA | NA |
| UHGV-0180216_53 | eggNOG-mapper | 1408437.JNJN01000043_gene801 | NA | NA |
| UHGV-0180216_54 | eggNOG-mapper | 1408437.JNJN01000043_gene802 | NA | NA |
| UHGV-0180216_55 | PHROG | phrog_16490 | NA | unknown function |
| UHGV-0180216_55 | eggNOG-mapper | 1408437.JNJN01000043_gene803 | NA | NA |
| UHGV-0180216_60 | PHROG | phrog_15303 | NA | unknown function |
| UHGV-0180216_62 | KOfam | K07273 | acm; lysozyme | NA |
| UHGV-0180216_62 | PHROG | phrog_291 | endolysin | lysis |
| UHGV-0180216_62 | UniRef90 | UniRef90_A0A564U0D3 | Autolytic lysozyme | NA |
| UHGV-0180216_62 | eggNOG-mapper | 718252.FP2_04890 | hydrolase, family 25 | NA |
| UHGV-0180216_62 | Pfam | PF01183 | Glycosyl hydrolases family 25 | Glyco_hydro_25 |
| UHGV-0180216_62 | COG | COG3757 | Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family | NA |
| UHGV-0180216_62 | Structural annotation | PF01183, TIGR04053, COG3757 | NA | NA |
| UHGV-0180216_63 | Structural annotation | PF02368, NF038186 | NA | NA |
| UHGV-0180216_64 | PHROG | phrog_20274 | NA | unknown function |
| UHGV-0180216_64 | UniRef90 | UniRef90_D4KC19 | Predicted membrane protein | NA |
| UHGV-0180216_64 | eggNOG-mapper | 657322.FPR_21900 | NA | NA |
| UHGV-0180216_64 | Pfam | PF06541 | Putative ABC-transporter type IV | ABC_trans_CmpB |
| UHGV-0180216_64 | COG | COG4905 | NA | NA |
| UHGV-0180216_64 | Structural annotation | PF06541, COG4905 | NA | NA |
| UHGV-0180216_65 | UniRef90 | UniRef90_A0A2N0K3B0 | Acyl carrier protein | NA |
| UHGV-0180216_65 | eggNOG-mapper | 693746.OBV_01640 | NA | NA |
| UHGV-0180216_65 | Structural annotation | PF14301 | NA | NA |
| UHGV-0180216_67 | PHROG | phrog_18725 | NA | unknown function |
| UHGV-0180216_67 | eggNOG-mapper | 1226322.HMPREF1545_00062 | NA | NA |
| UHGV-0180216_68 | PHROG | phrog_13879 | NA | unknown function |
| UHGV-0180216_68 | eggNOG-mapper | 324057.Pjdr2_1554 | NA | NA |
| UHGV-0180216_68 | Pfam | PF02368 | Bacterial Ig-like domain (group 2) | Big_2 |
| UHGV-0180216_68 | Pfam | PF19789 | NA | DUF6273 |
| UHGV-0180216_68 | Structural annotation | PF14594, PF19789, PF03256, PF09134, NF033848, COG3500, COG5156 | NA | NA |
| UHGV-0180216_69 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-0180216_69 | eggNOG-mapper | 665956.HMPREF1032_03629 | NA | NA |
| UHGV-0180216_69 | Pfam | PF20458 | NA | DUF6711 |
| UHGV-0180216_69 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-0180216_70 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-0180216_70 | eggNOG-mapper | 1121866.AUGK01000003_gene1437 | phage tail tape measure protein | NA |
| UHGV-0180216_70 | COG | COG1280 | Threonine/homoserine/homoserine lactone efflux protein | NA |
| UHGV-0180216_71 | eggNOG-mapper | 1121333.JMLH01000047_gene1011 | NA | NA |
| UHGV-0180216_72 | UniRef90 | UniRef90_A0A847YX95 | NA | NA |
| UHGV-0180216_72 | eggNOG-mapper | 1123263.AUKY01000015_gene1618 | NA | NA |
| UHGV-0180216_72 | Pfam | PF16478 | NA | DUF5055 |
| UHGV-0180216_72 | Structural annotation | PF16478 | NA | NA |
| UHGV-0180216_73 | PHROG | phrog_158 | major tail protein | tail |
| UHGV-0180216_73 | UniRef90 | UniRef90_UPI001D087591 | phage tail protein | NA |
| UHGV-0180216_73 | eggNOG-mapper | 1449343.JQLQ01000002_gene1514 | Phage tail tube protein, TTP | NA |
| UHGV-0180216_73 | Structural annotation | PF16463, TIGR02241, COG5437 | NA | NA |
| UHGV-0180216_74 | Structural annotation | PF06141, TIGR02367, COG3167 | NA | NA |
| UHGV-0180216_75 | eggNOG-mapper | 476272.RUMHYD_01963 | NA | NA |
| UHGV-0180216_76 | eggNOG-mapper | 1298920.KI911353_gene2656 | NA | NA |
| UHGV-0180216_76 | Structural annotation | PF19586, TIGR01563, COG5614 | NA | NA |
| UHGV-0180216_77 | UniRef90 | UniRef90_R6N215 | Phage QLRG family putative DNA packaging | NA |
| UHGV-0180216_77 | Structural annotation | TIGR01560 | NA | NA |
| UHGV-0180216_78 | PHROG | phrog_29 | major head protein | head and packaging |
| UHGV-0180216_78 | UniRef90 | UniRef90_A0A2Z4QBB4 | Major capsid protein E | NA |
| UHGV-0180216_78 | eggNOG-mapper | 1347368.HG964404_gene4993 | Phage major capsid protein E | NA |
| UHGV-0180216_78 | Pfam | PF03864 | Phage major capsid protein E | Phage_cap_E |
| UHGV-0180216_78 | Structural annotation | PF03864, MF_04133, NF041162, COG4653 | NA | NA |
| UHGV-0180216_81 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-0180216_81 | UniRef90 | UniRef90_A0A371ILT4 | Phage portal protein | NA |
| UHGV-0180216_81 | eggNOG-mapper | 1121866.AUGK01000003_gene1429 | Phage portal protein, SPP1 Gp6-like | NA |
| UHGV-0180216_81 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-0180216_81 | Structural annotation | PF05133, MF_04120, TIGR01538, COG5511 | NA | NA |
| UHGV-0180216_83 | PHROG | phrog_38 | terminase large subunit | head and packaging |
| UHGV-0180216_83 | UniRef90 | UniRef90_UPI000419A6BC | phage terminase large subunit | NA |
| UHGV-0180216_83 | eggNOG-mapper | 1121866.AUGK01000003_gene1428 | chromosome segregation | NA |
| UHGV-0180216_83 | COG | COG5410 | NA | NA |
| UHGV-0180216_83 | Structural annotation | PF17289, PF02562, MF_04147, NF033889, COG5362, COG5410 | NA | NA |
| UHGV-0180216_84 | KOfam | K14415 | RTCB, rtcB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8] | NA |
| UHGV-0180216_84 | PHROG | phrog_1075 | tRNA splicing ligase | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_84 | UniRef90 | UniRef90_UPI00067F3ABF | RNA-splicing ligase RtcB | NA |
| UHGV-0180216_84 | eggNOG-mapper | 1211844.CBLM010000044_gene358 | tRNA-splicing ligase RtcB | NA |
| UHGV-0180216_84 | Pfam | PF01139 | tRNA-splicing ligase RtcB | RtcB |
| UHGV-0180216_84 | COG | COG1690 | RNA-splicing ligase RtcB, repairs tRNA damage | NA |
| UHGV-0180216_84 | Structural annotation | PF01139, MF_03144, NF007153, COG1690 | NA | NA |
| UHGV-0180216_85 | KOfam | K14060 | pinR; putative DNA-invertase from lambdoid prophage Rac | NA |
| UHGV-0180216_85 | PHROG | phrog_125 | DNA invertase | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_85 | UniRef90 | UniRef90_A0A3D0LYX8 | Resolvase | NA |
| UHGV-0180216_85 | eggNOG-mapper | 411469.EUBHAL_01860 | Resolvase, N terminal domain | NA |
| UHGV-0180216_85 | Pfam | PF00239 | Resolvase, N terminal domain | Resolvase |
| UHGV-0180216_85 | COG | COG1961 | Site-specific DNA recombinase SpoIVCA/DNA invertase PinE | NA |
| UHGV-0180216_85 | Structural annotation | PF00239, PF02796, MF_00489, NF009949, COG1961 | NA | NA |
| UHGV-0180216_88 | Structural annotation | PF19807, NF041793, COG4877 | NA | NA |
| UHGV-0180216_89 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0180216_89 | PHROG | phrog_373 | anti-repressor | transcription regulation |
| UHGV-0180216_89 | UniRef90 | UniRef90_A0A6N8HZA6 | AntA/AntB antirepressor | NA |
| UHGV-0180216_89 | eggNOG-mapper | 903814.ELI_3141 | AntA/AntB antirepressor | NA |
| UHGV-0180216_89 | Pfam | PF08346 | AntA/AntB antirepressor | AntA |
| UHGV-0180216_89 | Pfam | PF10552 | ORF6C domain | ORF6C |
| UHGV-0180216_89 | COG | COG3561 | Phage anti-repressor protein Ant | NA |
| UHGV-0180216_89 | Structural annotation | PF10552, PF08346, TIGR02681, COG3561 | NA | NA |
| UHGV-0180216_91 | NCBIFam | NF038353.1 | FxLYD domain-containing protein | NA |
| UHGV-0180216_91 | COG | COG0515 | Serine/threonine protein kinase | NA |
| UHGV-0180216_91 | Structural annotation | PF09624, PF14263, MF_00791, NF038353, TIGR02588, COG4885 | NA | NA |
| UHGV-0180216_96 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0180216_96 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-0180216_100 | Structural annotation | PF17340 | NA | NA |