| UHGV-0189865_1 | PHROG | phrog_4433 | NA | unknown function |
| UHGV-0189865_1 | eggNOG-mapper | 665950.HMPREF1025_01373 | regulation of DNA-templated transcription, elongation | NA |
| UHGV-0189865_1 | COG | COG5164 | Transcription elongation factor SPT5 | NA |
| UHGV-0189865_9 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-0189865_9 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0189865_9 | UniRef90 | UniRef90_UPI0015702B9F | helix-turn-helix domain-containing protein | NA |
| UHGV-0189865_9 | eggNOG-mapper | 908340.HMPREF9406_2608 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0189865_9 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0189865_9 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0189865_9 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0189865_13 | KOfam | K14059 | int; integrase | NA |
| UHGV-0189865_13 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0189865_13 | UniRef90 | UniRef90_A0A353J242 | Site-specific integrase | NA |
| UHGV-0189865_13 | eggNOG-mapper | 246199.CUS_5913 | Phage integrase family | NA |
| UHGV-0189865_13 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-0189865_13 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0189865_13 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0189865_13 | Structural annotation | PF00589, PF12167, MF_02055, NF040815, COG4974 | NA | NA |
| UHGV-0189865_14 | Structural annotation | PF02255, TIGR00823 | NA | NA |
| UHGV-0189865_16 | UniRef90 | UniRef90_A0A1Y3RJS2 | Sigma70_r4_2 domain-containing protein | NA |
| UHGV-0189865_17 | Structural annotation | PF08281, TIGR02983 | NA | NA |
| UHGV-0189865_18 | PHROG | phrog_199 | holin | lysis |
| UHGV-0189865_18 | UniRef90 | UniRef90_UPI001C00C30F | phage holin family protein | NA |
| UHGV-0189865_18 | eggNOG-mapper | 411467.BACCAP_00280 | Bacteriophage holin family | NA |
| UHGV-0189865_18 | Pfam | PF05105 | Bacteriophage holin family | Phage_holin_4_1 |
| UHGV-0189865_18 | NCBIFam | TIGR01593.1 | toxin secretion/phage lysis holin | NA |
| UHGV-0189865_18 | COG | COG4824 | Phage-related holin (Lysis protein) | NA |
| UHGV-0189865_18 | Structural annotation | PF05105, TIGR01593, COG4824 | NA | NA |
| UHGV-0189865_19 | UniRef90 | UniRef90_A0A2V2FP98 | SH3b domain-containing protein | NA |
| UHGV-0189865_19 | Pfam | PF08239 | Bacterial SH3 domain | SH3_3 |
| UHGV-0189865_19 | COG | COG3103 | NA | NA |
| UHGV-0189865_19 | Structural annotation | PF08239, PF00877, NF008096, COG4991, COG0791 | NA | NA |
| UHGV-0189865_21 | KOfam | K13884 | MARCO; macrophage receptor with collagenous structure | NA |
| UHGV-0189865_21 | PHROG | phrog_6320 | tail fiber protein | tail |
| UHGV-0189865_21 | eggNOG-mapper | 476272.RUMHYD_00002 | NA | NA |
| UHGV-0189865_21 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | Collagen |
| UHGV-0189865_22 | PHROG | phrog_5811 | NA | unknown function |
| UHGV-0189865_22 | eggNOG-mapper | 1408321.JNJD01000007_gene173 | Glycine rich protein | NA |
| UHGV-0189865_22 | Pfam | PF12810 | Glycine rich protein | Gly_rich |
| UHGV-0189865_24 | eggNOG-mapper | 755731.Clo1100_2421 | NA | NA |
| UHGV-0189865_24 | Pfam | PF18798 | Large polyvalent protein-associated domain 3 | LPD3 |
| UHGV-0189865_27 | PHROG | phrog_511 | internal virion protein | head and packaging |
| UHGV-0189865_27 | eggNOG-mapper | 1449126.JQKL01000046_gene2081 | NA | NA |
| UHGV-0189865_27 | COG | COG4722 | Phage-related protein YomH | NA |
| UHGV-0189865_27 | Structural annotation | PF11134, MF_03022, NF010237, TIGR04362, COG5276 | NA | NA |
| UHGV-0189865_28 | Structural annotation | PF20387 | NA | NA |
| UHGV-0189865_30 | PHROG | phrog_1357 | major head protein | head and packaging |
| UHGV-0189865_30 | UniRef90 | UniRef90_UPI001CF8B373 | N4-gp56 family major capsid protein | NA |
| UHGV-0189865_30 | eggNOG-mapper | 696281.Desru_1092 | NA | NA |
| UHGV-0189865_30 | Pfam | PF13252 | NA | DUF4043 |
| UHGV-0189865_30 | NCBIFam | TIGR04387.1 | N4-gp56 family major capsid protein | NA |
| UHGV-0189865_30 | Structural annotation | PF13252, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-0189865_32 | PHROG | phrog_156 | portal protein | head and packaging |
| UHGV-0189865_32 | eggNOG-mapper | 1203606.HMPREF1526_02749 | NA | NA |
| UHGV-0189865_32 | Structural annotation | PF16510, MF_04120, TIGR01538, COG5511 | NA | NA |
| UHGV-0189865_33 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0189865_33 | PHROG | phrog_979 | terminase large subunit | head and packaging |
| UHGV-0189865_33 | UniRef90 | UniRef90_UPI0004130EC4 | phage terminase large subunit | NA |
| UHGV-0189865_33 | eggNOG-mapper | 1121091.AUMP01000003_gene2581 | Terminase-like family | NA |
| UHGV-0189865_33 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-0189865_33 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0189865_33 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0189865_34 | Pfam | PF04545 | Sigma-70, region 4 | Sigma70_r4 |
| UHGV-0189865_34 | Structural annotation | PF02796, TIGR02844 | NA | NA |
| UHGV-0189865_36 | PHROG | phrog_15863 | NA | unknown function |
| UHGV-0189865_36 | UniRef90 | UniRef90_A0A498RA91 | J domain-containing protein | NA |
| UHGV-0189865_36 | eggNOG-mapper | 1476583.DEIPH_ctg060orf0032 | Heat shock protein DnaJ domain protein | NA |
| UHGV-0189865_36 | COG | COG2214 | Curved DNA-binding protein CbpA, contains a DnaJ-like domain | NA |
| UHGV-0189865_40 | Structural annotation | PF07374, TIGR01636 | NA | NA |
| UHGV-0189865_41 | UniRef90 | UniRef90_A0A832L5E4 | Crossover junction endodeoxyribonuclease RuvC | NA |
| UHGV-0189865_41 | eggNOG-mapper | 1304885.AUEY01000070_gene1852 | NA | NA |
| UHGV-0189865_41 | Structural annotation | PF02075, MF_00034, NF000711, COG0817 | NA | NA |
| UHGV-0189865_42 | Structural annotation | TIGR03655 | NA | NA |
| UHGV-0189865_43 | KOfam | K19779 | ralR; endodeoxyribonuclease RalR [EC:3.1.-.-] | NA |
| UHGV-0189865_43 | PHROG | phrog_599 | Lar-like restriction alleviation protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-0189865_43 | UniRef90 | UniRef90_UPI001C8D6ADC | Lar family restriction alleviation protein | NA |
| UHGV-0189865_43 | eggNOG-mapper | 220341.16503116 | Toxic component of a type I toxin-antitoxin (TA) system. Upon overexpression inhibits growth and reduces colony-forming units in both the presence and absence of the Rac prophage, cells become filamentous. Has deoxyribonuclease activity (probably endonucleolytic), does not digest RNA. Its toxic effects are neutralized by sRNA antitoxin RalA, which is encoded in trans on the opposite DNA strand. Has RAL-like activity | NA |
| UHGV-0189865_43 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-0189865_43 | NCBIFam | TIGR03655.1 | Lar family restriction alleviation protein | NA |
| UHGV-0189865_43 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-0189865_43 | Structural annotation | PF14354, NF007260 | NA | NA |
| UHGV-0189865_45 | PHROG | phrog_757 | DNA methyltransferase | other |
| UHGV-0189865_45 | UniRef90 | UniRef90_A0A6M3LEH2 | Putative methyltransferase | NA |
| UHGV-0189865_45 | eggNOG-mapper | 1247726.MIM_c10510 | DNA (cytosine-5-)-methyltransferase activity | NA |
| UHGV-0189865_45 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0189865_46 | PHROG | phrog_757 | DNA methyltransferase | other |
| UHGV-0189865_46 | UniRef90 | UniRef90_A0A7J2R6L5 | DNA cytosine methyltransferase (Fragment) | NA |
| UHGV-0189865_46 | eggNOG-mapper | 748224.HMPREF9436_03069 | DNA (cytosine-5-)-methyltransferase activity | NA |
| UHGV-0189865_46 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0189865_47 | UniRef90 | UniRef90_UPI00054386A4 | nucleotide pyrophosphohydrolase | NA |
| UHGV-0189865_47 | eggNOG-mapper | 743719.PaelaDRAFT_2380 | Mazg nucleotide pyrophosphohydrolase | NA |
| UHGV-0189865_47 | Pfam | PF12643 | MazG-like family | MazG-like |
| UHGV-0189865_47 | COG | COG1694 | NTP pyrophosphatase, house-cleaning of non-canonical NTPs | NA |
| UHGV-0189865_47 | Structural annotation | COG1694 | NA | NA |
| UHGV-0189865_49 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0189865_49 | PHROG | phrog_130 | anti-repressor Ant | transcription regulation |
| UHGV-0189865_49 | UniRef90 | UniRef90_A0A417H802 | Bro-N domain-containing protein | NA |
| UHGV-0189865_49 | eggNOG-mapper | 1437608.BBIA_0645 | BRO family, N-terminal domain | NA |
| UHGV-0189865_49 | Pfam | PF02498 | BRO family, N-terminal domain | Bro-N |
| UHGV-0189865_49 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0189865_49 | COG | COG3617 | Prophage antirepressor | NA |
| UHGV-0189865_49 | Structural annotation | PF02498, PF03374, TIGR02681, COG3645, COG3561 | NA | NA |
| UHGV-0189865_50 | PHROG | phrog_9804 | NA | unknown function |
| UHGV-0189865_50 | UniRef90 | UniRef90_UPI0015C5D332 | replicative helicase loader/inhibitor | NA |
| UHGV-0189865_50 | eggNOG-mapper | 1121344.JHZO01000003_gene981 | Loader and inhibitor of phage G40P | NA |
| UHGV-0189865_50 | Pfam | PF11417 | Loader and inhibitor of phage G40P | Inhibitor_G39P |
| UHGV-0189865_50 | Structural annotation | PF11417 | NA | NA |
| UHGV-0189865_51 | PHROG | phrog_15768 | NA | unknown function |
| UHGV-0189865_51 | eggNOG-mapper | 1121344.JHZO01000003_gene982 | NA | NA |
| UHGV-0189865_51 | Pfam | PF19808 | NA | DUF6291 |
| UHGV-0189865_51 | Structural annotation | PF19808 | NA | NA |
| UHGV-0189865_52 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0189865_52 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0189865_52 | UniRef90 | UniRef90_A0A2V2FMD6 | Single-stranded DNA-binding protein | NA |
| UHGV-0189865_52 | eggNOG-mapper | 1226322.HMPREF1545_04080 | Single-strand binding protein family | NA |
| UHGV-0189865_52 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0189865_52 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0189865_52 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0189865_52 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0189865_52 | Structural annotation | PF00436, MF_00984, NF005241, COG0629 | NA | NA |
| UHGV-0189865_53 | PHROG | phrog_155 | Erf-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0189865_53 | UniRef90 | UniRef90_UPI0006B5ECE1 | ERF family protein | NA |
| UHGV-0189865_53 | eggNOG-mapper | 357809.Cphy_2988 | ERF superfamily | NA |
| UHGV-0189865_53 | Pfam | PF04404 | ERF superfamily | ERF |
| UHGV-0189865_53 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0189865_53 | Structural annotation | PF04404, COG4712 | NA | NA |
| UHGV-0189865_54 | PHROG | phrog_253 | Mu Gam-like end protection | DNA, RNA and nucleotide metabolism |
| UHGV-0189865_54 | UniRef90 | UniRef90_UPI000C7CF4DA | siphovirus Gp157 family protein | NA |
| UHGV-0189865_54 | eggNOG-mapper | 1121091.AUMP01000003_gene2548 | Siphovirus Gp157 | NA |
| UHGV-0189865_54 | Pfam | PF05565 | Siphovirus Gp157 | Sipho_Gp157 |
| UHGV-0189865_54 | Structural annotation | PF05565 | NA | NA |
| UHGV-0189865_56 | Structural annotation | PF20800 | NA | NA |
| UHGV-0189865_58 | Structural annotation | PF13443, NF041951, COG3655 | NA | NA |
| UHGV-0189865_59 | PHROG | phrog_27197 | NA | unknown function |
| UHGV-0189865_59 | eggNOG-mapper | 886882.PPSC2_p0048 | regulation of DNA-templated transcription, elongation | NA |
| UHGV-0189865_59 | COG | COG5164 | Transcription elongation factor SPT5 | NA |
| UHGV-0189865_59 | Structural annotation | NF007410 | NA | NA |