| UHGV-0214520_3 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0214520_3 | Structural annotation | PF07374, TIGR01636, COG2739 | NA | NA |
| UHGV-0214520_5 | KOfam | K02314 | dnaB; replicative DNA helicase [EC:5.6.2.3] | NA |
| UHGV-0214520_5 | PHROG | phrog_19 | DnaB-like replicative helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0214520_5 | UniRef90 | UniRef90_UPI00196123BF | replicative DNA helicase | NA |
| UHGV-0214520_5 | eggNOG-mapper | 97138.C820_00625 | Participates in initiation and elongation during chromosome replication | NA |
| UHGV-0214520_5 | Pfam | PF00772 | DnaB-like helicase N terminal domain | DnaB |
| UHGV-0214520_5 | Pfam | PF03796 | DnaB-like helicase C terminal domain | DnaB_C |
| UHGV-0214520_5 | NCBIFam | TIGR00665.1 | replicative DNA helicase | NA |
| UHGV-0214520_5 | COG | COG0305 | Replicative DNA helicase | NA |
| UHGV-0214520_5 | Structural annotation | PF03796, PF00772, MF_04155, TIGR00665, COG0305 | NA | NA |
| UHGV-0214520_6 | PHROG | phrog_6251 | replisome organizer DnaA-like | DNA, RNA and nucleotide metabolism |
| UHGV-0214520_6 | UniRef90 | UniRef90_R5AB02 | DnaD domain protein | NA |
| UHGV-0214520_6 | eggNOG-mapper | 1078085.HMPREF1210_01172 | dnaD_dom DnaD domain protein | NA |
| UHGV-0214520_6 | COG | COG3935 | DNA replication protein DnaD | NA |
| UHGV-0214520_6 | Structural annotation | PF09681, TIGR01714, COG1846 | NA | NA |
| UHGV-0214520_7 | UniRef90 | UniRef90_A0A2M7VKA3 | XRE family transcriptional regulator | NA |
| UHGV-0214520_7 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0214520_9 | eggNOG-mapper | 476272.RUMHYD_03328 | NA | NA |
| UHGV-0214520_10 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0214520_10 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0214520_10 | UniRef90 | UniRef90_R6Q6X2 | Single-stranded DNA-binding protein | NA |
| UHGV-0214520_10 | eggNOG-mapper | 97138.C820_02339 | Single-stranded DNA-binding protein | NA |
| UHGV-0214520_10 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0214520_10 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0214520_10 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0214520_10 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0214520_10 | Structural annotation | PF00436, MF_00984, NF005242, COG0629 | NA | NA |
| UHGV-0214520_11 | eggNOG-mapper | 411473.RUMCAL_02525 | NA | NA |
| UHGV-0214520_17 | KOfam | K19779 | ralR; endodeoxyribonuclease RalR [EC:3.1.-.-] | NA |
| UHGV-0214520_17 | PHROG | phrog_599 | Lar-like restriction alleviation protein | moron, auxiliary metabolic gene and host takeover |
| UHGV-0214520_17 | Pfam | PF14354 | Restriction alleviation protein Lar | Lar_restr_allev |
| UHGV-0214520_17 | NCBIFam | TIGR03655.1 | Lar family restriction alleviation protein | NA |
| UHGV-0214520_17 | dbAPIS | APIS033 | Lar is functionally similar to RaI, is able to alleviate restriction and enhance modification by EcoKI. And the nucleotide sequences of their genes share 47% identity, indicating a common origin. | NA |
| UHGV-0214520_17 | Structural annotation | PF14354, TIGR03655 | NA | NA |
| UHGV-0214520_18 | Structural annotation | PF14354, TIGR03655 | NA | NA |
| UHGV-0214520_19 | PHROG | phrog_2776 | NA | unknown function |
| UHGV-0214520_19 | eggNOG-mapper | 697329.Rumal_3412 | NA | NA |
| UHGV-0214520_19 | Structural annotation | PF06319, NF033832, COG5321 | NA | NA |
| UHGV-0214520_20 | eggNOG-mapper | 1235835.C814_01169 | NA | NA |
| UHGV-0214520_20 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0214520_21 | PHROG | phrog_424 | phosphoadenosine phosphosulfate reductase | moron, auxiliary metabolic gene and host takeover |
| UHGV-0214520_21 | UniRef90 | UniRef90_UPI0018774E0E | reductase | NA |
| UHGV-0214520_21 | eggNOG-mapper | 1235835.C814_01169 | NA | NA |
| UHGV-0214520_21 | COG | COG0175 | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme | NA |
| UHGV-0214520_21 | Structural annotation | PF01507, MF_03053, TIGR02057, COG1606 | NA | NA |
| UHGV-0214520_23 | PHROG | phrog_7566 | NA | unknown function |
| UHGV-0214520_23 | eggNOG-mapper | 508419.F8J187_9CAUD | NA | NA |
| UHGV-0214520_25 | PHROG | phrog_1029 | NA | unknown function |
| UHGV-0214520_25 | UniRef90 | UniRef90_A0A4V6L4T1 | NA | NA |
| UHGV-0214520_25 | eggNOG-mapper | 1158607.UAU_01007 | NA | NA |
| UHGV-0214520_26 | PHROG | phrog_1029 | NA | unknown function |
| UHGV-0214520_26 | eggNOG-mapper | 1211817.CCAT010000049_gene2467 | NA | NA |
| UHGV-0214520_27 | PHROG | phrog_997 | replication terminator | DNA, RNA and nucleotide metabolism |
| UHGV-0214520_27 | UniRef90 | UniRef90_R6Q5I9 | Replication terminator protein phage associated | NA |
| UHGV-0214520_27 | eggNOG-mapper | 1231377.C426_1299 | NA | NA |
| UHGV-0214520_29 | Structural annotation | PF13744, MF_00535, NF010465, COG3655 | NA | NA |
| UHGV-0214520_34 | UniRef90 | UniRef90_UPI000EA3EFDD | Arc family DNA-binding protein | NA |
| UHGV-0214520_34 | eggNOG-mapper | 1121121.KB894312_gene3201 | NA | NA |
| UHGV-0214520_34 | Pfam | PF03869 | Arc-like DNA binding domain | Arc |
| UHGV-0214520_34 | Structural annotation | PF03869, NF008671, COG4877 | NA | NA |
| UHGV-0214520_35 | UniRef90 | UniRef90_A0A4S2AGE3 | Ribbon-helix-helix protein, CopG family | NA |
| UHGV-0214520_35 | Pfam | PF01402 | Ribbon-helix-helix protein, copG family | RHH_1 |
| UHGV-0214520_35 | Structural annotation | PF12441, TIGR04563, COG4877 | NA | NA |
| UHGV-0214520_37 | KOfam | K18830 | pezA; HTH-type transcriptional regulator / antitoxin PezA | NA |
| UHGV-0214520_37 | PHROG | phrog_2967 | transcriptional regulator | transcription regulation |
| UHGV-0214520_37 | UniRef90 | UniRef90_A0A645CRG5 | HTH cro/C1-type domain-containing protein | NA |
| UHGV-0214520_37 | eggNOG-mapper | 1235800.C819_02266 | Helix-turn-helix XRE-family like proteins | NA |
| UHGV-0214520_37 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0214520_37 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0214520_37 | Structural annotation | PF01381, MF_00535, NF041951, COG1476 | NA | NA |
| UHGV-0214520_40 | KOfam | K14059 | int; integrase | NA |
| UHGV-0214520_40 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0214520_40 | UniRef90 | UniRef90_R7AP99 | Tyr recombinase domain-containing protein | NA |
| UHGV-0214520_40 | eggNOG-mapper | 1226322.HMPREF1545_00144 | Belongs to the 'phage' integrase family | NA |
| UHGV-0214520_40 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-0214520_40 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0214520_40 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0214520_40 | Structural annotation | PF00589, PF12167, MF_02055, NF040815, COG4974 | NA | NA |
| UHGV-0214520_41 | eggNOG-mapper | 1408437.JNJN01000039_gene389 | heme binding | NA |
| UHGV-0214520_41 | COG | COG0739 | Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain | NA |
| UHGV-0214520_43 | KOfam | K01448 | amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0214520_43 | PHROG | phrog_435 | endolysin | lysis |
| UHGV-0214520_43 | UniRef90 | UniRef90_R6PPN0 | Cell wall hydrolase/autolysin | NA |
| UHGV-0214520_43 | eggNOG-mapper | 97138.C820_02438 | Ami_3 | NA |
| UHGV-0214520_43 | Pfam | PF01520 | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
| UHGV-0214520_43 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0214520_43 | Structural annotation | PF01520, MF_00562, TIGR02883, COG0860 | NA | NA |
| UHGV-0214520_44 | PHROG | phrog_355 | nucleoside 2-deoxyribosyltransferase | DNA, RNA and nucleotide metabolism |
| UHGV-0214520_44 | UniRef90 | UniRef90_UPI00156F0E9C | NA | NA |
| UHGV-0214520_44 | eggNOG-mapper | 1256908.HMPREF0373_00479 | NA | NA |
| UHGV-0214520_44 | Pfam | PF14359 | NA | DUF4406 |
| UHGV-0214520_44 | Structural annotation | PF14359, COG3613 | NA | NA |
| UHGV-0214520_45 | UniRef90 | UniRef90_A0A1M6QSY5 | Holin, phage phi LC3 family | NA |
| UHGV-0214520_45 | eggNOG-mapper | 97138.C820_02010 | Bacteriophage holin | NA |
| UHGV-0214520_45 | Pfam | PF04531 | Bacteriophage holin | Phage_holin_1 |
| UHGV-0214520_45 | NCBIFam | TIGR01598.1 | phage holin | NA |
| UHGV-0214520_45 | COG | COG5546 | NA | NA |
| UHGV-0214520_47 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-0214520_47 | UniRef90 | UniRef90_UPI00189A7662 | NA | NA |
| UHGV-0214520_47 | eggNOG-mapper | 1134413.ANNK01000120_gene2028 | NA | NA |
| UHGV-0214520_47 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-0214520_47 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-0214520_47 | Structural annotation | PF11195 | NA | NA |
| UHGV-0214520_53 | Pfam | PF18454 | Major tropism determinant N-terminal domain | Mtd_N |
| UHGV-0214520_53 | COG | COG5301 | Phage-related tail fiber protein | NA |
| UHGV-0214520_54 | PHROG | phrog_38707 | NA | unknown function |
| UHGV-0214520_54 | UniRef90 | UniRef90_A0A415E167 | Mtd_N domain-containing protein | NA |
| UHGV-0214520_54 | eggNOG-mapper | 742738.HMPREF9460_03963 | tail collar domain protein | NA |
| UHGV-0214520_54 | Pfam | PF18454 | Major tropism determinant N-terminal domain | Mtd_N |
| UHGV-0214520_54 | COG | COG4675 | Phage tail collar domain | NA |
| UHGV-0214520_55 | eggNOG-mapper | 665956.HMPREF1032_03261 | NA | NA |
| UHGV-0214520_56 | PHROG | phrog_3287 | virion structural protein | head and packaging |
| UHGV-0214520_56 | eggNOG-mapper | 665956.HMPREF1032_03917 | NA | NA |
| UHGV-0214520_56 | Structural annotation | PF11134, MF_01282, TIGR03300, COG5276 | NA | NA |
| UHGV-0214520_57 | eggNOG-mapper | 693746.OBV_23880 | NA | NA |
| UHGV-0214520_57 | Structural annotation | PF20387 | NA | NA |
| UHGV-0214520_58 | PHROG | phrog_371 | major head protein | head and packaging |
| UHGV-0214520_58 | UniRef90 | UniRef90_UPI00164C0E21 | Mu-like prophage major head subunit gpT family protein | NA |
| UHGV-0214520_58 | eggNOG-mapper | 1226322.HMPREF1545_03848 | NA | NA |
| UHGV-0214520_58 | Pfam | PF10124 | Mu-like prophage major head subunit gpT | Mu-like_gpT |
| UHGV-0214520_58 | Structural annotation | PF05065, MF_04119, TIGR01554, COG4653 | NA | NA |
| UHGV-0214520_59 | PHROG | phrog_24113 | NA | unknown function |
| UHGV-0214520_59 | eggNOG-mapper | 1226322.HMPREF1545_03847 | NA | NA |
| UHGV-0214520_59 | Structural annotation | PF11133, COG5471 | NA | NA |
| UHGV-0214520_60 | PHROG | phrog_35275 | NA | unknown function |
| UHGV-0214520_60 | eggNOG-mapper | 693746.OBV_23910 | NA | NA |
| UHGV-0214520_63 | PHROG | phrog_156 | portal protein | head and packaging |
| UHGV-0214520_63 | eggNOG-mapper | 693746.OBV_23930 | NA | NA |
| UHGV-0214520_63 | Structural annotation | PF16510, MF_04120, TIGR01542, COG4695 | NA | NA |
| UHGV-0214520_64 | KOfam | K04763 | xerD; integrase/recombinase XerD | NA |
| UHGV-0214520_64 | PHROG | phrog_216 | integrase | integration and excision |
| UHGV-0214520_64 | UniRef90 | UniRef90_UPI001961BF9C | tyrosine-type recombinase/integrase | NA |
| UHGV-0214520_64 | eggNOG-mapper | 97138.C820_00621 | integrase family | NA |
| UHGV-0214520_64 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0214520_64 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0214520_64 | Structural annotation | PF00589, MF_02055, NF040815, COG4973 | NA | NA |
| UHGV-0214520_65 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-0214520_65 | UniRef90 | UniRef90_R5AHR8 | Putative terminase large subunit | NA |
| UHGV-0214520_65 | eggNOG-mapper | 693746.OBV_23980 | phage Terminase large subunit | NA |
| UHGV-0214520_65 | COG | COG4373 | Mu-like prophage FluMu protein gp28 | NA |
| UHGV-0214520_65 | Structural annotation | PF03237, PF17289, MF_04146, TIGR01547, COG4626 | NA | NA |
| UHGV-0214520_66 | PHROG | phrog_309 | terminase small subunit | head and packaging |
| UHGV-0214520_66 | UniRef90 | UniRef90_A0A316MA76 | Transposase | NA |
| UHGV-0214520_66 | eggNOG-mapper | 97138.C820_00620 | transposase activity | NA |
| UHGV-0214520_66 | COG | COG2963 | Transposase InsE and inactivated derivatives | NA |
| UHGV-0214520_66 | Structural annotation | PF07141 | NA | NA |
| UHGV-0214520_67 | KOfam | K06218 | relE, stbE; mRNA interferase RelE/StbE | NA |
| UHGV-0214520_67 | PHROG | phrog_1213 | RelE-like toxin | moron, auxiliary metabolic gene and host takeover |
| UHGV-0214520_67 | UniRef90 | UniRef90_A0A7X5RBC7 | Type II toxin-antitoxin system RelE/ParE family toxin | NA |
| UHGV-0214520_67 | eggNOG-mapper | 1235792.C808_02453 | Plasmid stabilization system | NA |
| UHGV-0214520_67 | Pfam | PF05016 | ParE toxin of type II toxin-antitoxin system, parDE | ParE_toxin |
| UHGV-0214520_67 | COG | COG2026 | mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system | NA |
| UHGV-0214520_67 | Structural annotation | PF05016, TIGR00053, COG2026 | NA | NA |
| UHGV-0214520_68 | eggNOG-mapper | 1235790.C805_01206 | NA | NA |
| UHGV-0214520_69 | PHROG | phrog_13890 | NA | unknown function |
| UHGV-0214520_69 | UniRef90 | UniRef90_A0A1C7FKE8 | Arc domain-containing protein | NA |
| UHGV-0214520_69 | eggNOG-mapper | 658655.HMPREF0988_00903 | NA | NA |
| UHGV-0214520_69 | Structural annotation | PF03869, NF010256, COG4710 | NA | NA |