| UHGV-0386307_1 | COG | COG3728 | Phage terminase, small subunit | NA |
| UHGV-0386307_2 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0386307_2 | PHROG | phrog_2 | terminase large subunit | head and packaging |
| UHGV-0386307_2 | UniRef90 | UniRef90_A0A7G5N2W3 | Terminase | NA |
| UHGV-0386307_2 | eggNOG-mapper | 742740.HMPREF9474_03500 | Phage terminase, large subunit, PBSX family | NA |
| UHGV-0386307_2 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0386307_2 | Structural annotation | PF03237, PF17289, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0386307_4 | PHROG | phrog_28292 | NA | unknown function |
| UHGV-0386307_4 | UniRef90 | UniRef90_A0A8B3BZ84 | 3-hydroxyacyl-CoA dehydrogenase | NA |
| UHGV-0386307_4 | eggNOG-mapper | 500632.CLONEX_01438 | NA | NA |
| UHGV-0386307_5 | PHROG | phrog_533 | portal protein | head and packaging |
| UHGV-0386307_5 | UniRef90 | UniRef90_A0A7G5N2W0 | Capsid protein | NA |
| UHGV-0386307_5 | eggNOG-mapper | 742740.HMPREF9474_03501 | NA | NA |
| UHGV-0386307_5 | Structural annotation | PF05133, MF_04120, TIGR01542, COG5511 | NA | NA |
| UHGV-0386307_6 | PHROG | phrog_581 | minor head protein | head and packaging |
| UHGV-0386307_6 | UniRef90 | UniRef90_UPI00148AF6EC | minor capsid protein | NA |
| UHGV-0386307_6 | eggNOG-mapper | 33035.JPJF01000093_gene2255 | NA | NA |
| UHGV-0386307_6 | Pfam | PF06152 | Phage minor capsid protein 2 | Phage_min_cap2 |
| UHGV-0386307_6 | COG | COG5585 | Putative phage head morphogenesis protein, F of phage Mu or gp7 of SPP1 | NA |
| UHGV-0386307_6 | Structural annotation | PF06152 | NA | NA |
| UHGV-0386307_8 | PHROG | phrog_2303 | head scaffolding protein | head and packaging |
| UHGV-0386307_8 | eggNOG-mapper | 742740.HMPREF9474_03504 | NA | NA |
| UHGV-0386307_9 | PHROG | phrog_422 | major head protein | head and packaging |
| UHGV-0386307_9 | UniRef90 | UniRef90_A0A7G5N2V5 | Capsid protein | NA |
| UHGV-0386307_9 | eggNOG-mapper | 742740.HMPREF9474_03505 | NA | NA |
| UHGV-0386307_9 | Structural annotation | PF19821, MF_04119, TIGR04387, COG4653 | NA | NA |
| UHGV-0386307_10 | PHROG | phrog_1378 | NA | unknown function |
| UHGV-0386307_10 | eggNOG-mapper | 742740.HMPREF9474_03506 | NA | NA |
| UHGV-0386307_11 | PHROG | phrog_541 | head-tail adaptor | connector |
| UHGV-0386307_11 | eggNOG-mapper | 33035.JPJF01000093_gene2250 | NA | NA |
| UHGV-0386307_12 | PHROG | phrog_8710 | NA | unknown function |
| UHGV-0386307_12 | eggNOG-mapper | 33035.JPJF01000093_gene2249 | NA | NA |
| UHGV-0386307_12 | Structural annotation | PF10665, TIGR01563, COG5614 | NA | NA |
| UHGV-0386307_13 | eggNOG-mapper | 33035.JPJF01000093_gene2248 | NA | NA |
| UHGV-0386307_13 | Structural annotation | PF11114 | NA | NA |
| UHGV-0386307_14 | PHROG | phrog_2595 | head-tail connector protein | connector |
| UHGV-0386307_14 | UniRef90 | UniRef90_UPI001D0627B3 | minor capsid protein | NA |
| UHGV-0386307_14 | eggNOG-mapper | 33035.JPJF01000093_gene2247 | NA | NA |
| UHGV-0386307_14 | Pfam | PF12691 | Bacteriophage minor capsid protein | Minor_capsid_3 |
| UHGV-0386307_14 | Structural annotation | PF12691, COG5003 | NA | NA |
| UHGV-0386307_15 | PHROG | phrog_820 | major tail protein | tail |
| UHGV-0386307_15 | eggNOG-mapper | 33035.JPJF01000093_gene2246 | NA | NA |
| UHGV-0386307_15 | Structural annotation | PF06199, TIGR02126, COG5437 | NA | NA |
| UHGV-0386307_16 | PHROG | phrog_8300 | NA | unknown function |
| UHGV-0386307_16 | eggNOG-mapper | 33035.JPJF01000093_gene2245 | NA | NA |
| UHGV-0386307_16 | Structural annotation | PF06854 | NA | NA |
| UHGV-0386307_17 | PHROG | phrog_8355 | NA | unknown function |
| UHGV-0386307_17 | UniRef90 | UniRef90_UPI00148B251E | Gp15 family bacteriophage protein | NA |
| UHGV-0386307_17 | eggNOG-mapper | 33035.JPJF01000093_gene2244 | NA | NA |
| UHGV-0386307_18 | PHROG | phrog_1535 | tail length tape measure protein | tail |
| UHGV-0386307_18 | UniRef90 | UniRef90_A0A1C5PIN9 | Phage-related protein | NA |
| UHGV-0386307_18 | eggNOG-mapper | 33035.JPJF01000093_gene2243 | phage tail tape measure protein | NA |
| UHGV-0386307_18 | COG | COG3941 | Phage tail tape-measure protein, controls tail length | NA |
| UHGV-0386307_18 | Structural annotation | PF20155, TIGR01760, COG3941 | NA | NA |
| UHGV-0386307_19 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-0386307_19 | eggNOG-mapper | 33035.JPJF01000093_gene2242 | NA | NA |
| UHGV-0386307_19 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-0386307_20 | PHROG | phrog_6616 | tail protein | tail |
| UHGV-0386307_20 | UniRef90 | UniRef90_A0A0J1FXD9 | Peptidase S74 domain-containing protein | NA |
| UHGV-0386307_20 | eggNOG-mapper | 476272.RUMHYD_01992 | NA | NA |
| UHGV-0386307_20 | Structural annotation | PF05113, NF033848, COG3500 | NA | NA |
| UHGV-0386307_21 | PHROG | phrog_11037 | NA | unknown function |
| UHGV-0386307_21 | UniRef90 | UniRef90_A0A7G5N2U5 | Peptidase M23 | NA |
| UHGV-0386307_21 | eggNOG-mapper | 33035.JPJF01000093_gene2240 | NlpC/P60 family | NA |
| UHGV-0386307_21 | Pfam | PF18013 | Phage tail lysozyme | Phage_lysozyme2 |
| UHGV-0386307_21 | Pfam | PF00877 | NlpC/P60 family | NLPC_P60 |
| UHGV-0386307_21 | COG | COG0791 | Cell wall-associated hydrolase, NlpC_P60 family | NA |
| UHGV-0386307_21 | Structural annotation | PF18013, PF05382, NF033742, COG0791 | NA | NA |
| UHGV-0386307_22 | PHROG | phrog_5073 | tail fiber protein | tail |
| UHGV-0386307_22 | eggNOG-mapper | 33035.JPJF01000093_gene2239 | NA | NA |
| UHGV-0386307_23 | KOfam | K24213 | C1QTNF9; complement C1q and tumor necrosis factor-related protein 9 | NA |
| UHGV-0386307_23 | PHROG | phrog_5073 | tail fiber protein | tail |
| UHGV-0386307_23 | UniRef90 | UniRef90_UPI001A9B4A5E | collagen-like protein | NA |
| UHGV-0386307_23 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | Collagen |
| UHGV-0386307_25 | PHROG | phrog_16164 | NA | unknown function |
| UHGV-0386307_25 | eggNOG-mapper | 33035.JPJF01000093_gene2236 | NA | NA |
| UHGV-0386307_25 | Structural annotation | PF10651, NF032891 | NA | NA |
| UHGV-0386307_26 | KOfam | K19721 | COL5AS; collagen type V/XI/XXIV/XXVII, alpha | NA |
| UHGV-0386307_26 | PHROG | phrog_819 | tail protein | tail |
| UHGV-0386307_26 | UniRef90 | UniRef90_A0A7G5N2U2 | Collagen-like protein | NA |
| UHGV-0386307_26 | eggNOG-mapper | 33035.JPJF01000093_gene2235 | Collagen triple helix repeat (20 copies) | NA |
| UHGV-0386307_26 | Pfam | PF01391 | Collagen triple helix repeat (20 copies) | Collagen |
| UHGV-0386307_26 | COG | COG3064 | Membrane protein TolA involved in colicin uptake | NA |
| UHGV-0386307_27 | PHROG | phrog_1863 | NA | unknown function |
| UHGV-0386307_27 | eggNOG-mapper | 748224.HMPREF9436_00408 | NA | NA |
| UHGV-0386307_28 | PHROG | phrog_918 | NA | unknown function |
| UHGV-0386307_28 | UniRef90 | UniRef90_UPI0004D82A84 | NA | NA |
| UHGV-0386307_28 | eggNOG-mapper | 357809.Cphy_2966 | NA | NA |
| UHGV-0386307_28 | Pfam | PF19791 | NA | DUF6275 |
| UHGV-0386307_28 | Structural annotation | PF19791 | NA | NA |
| UHGV-0386307_29 | PHROG | phrog_1129 | holin | lysis |
| UHGV-0386307_29 | UniRef90 | UniRef90_A0A1C7I437 | Holin | NA |
| UHGV-0386307_29 | eggNOG-mapper | 33035.JPJF01000093_gene2233 | Phage holin family Hol44, in holin superfamily V | NA |
| UHGV-0386307_29 | Pfam | PF16079 | Phage holin family Hol44, in holin superfamily V | Phage_holin_5_2 |
| UHGV-0386307_29 | Structural annotation | PF06946 | NA | NA |
| UHGV-0386307_30 | PHROG | phrog_2428 | NA | unknown function |
| UHGV-0386307_30 | UniRef90 | UniRef90_UPI00148B0430 | ABC transporter ATPase | NA |
| UHGV-0386307_30 | eggNOG-mapper | 632245.CLP_1645 | NA | NA |
| UHGV-0386307_30 | dbAPIS | APIS024 | Tad1 proteins are not an enzymes, but are 'sponges' that bind and sequester the immune signaling molecule (cyclic ADP-ribose or gcADPR) produced by TIR-domain proteins, thus decoupling phage sensing from immune effector activation and rendering Thoeris inactive. | NA |
| UHGV-0386307_31 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-0386307_31 | UniRef90 | UniRef90_UPI00148B1F1A | NA | NA |
| UHGV-0386307_31 | eggNOG-mapper | 457412.RSAG_01107 | NA | NA |
| UHGV-0386307_31 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-0386307_31 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-0386307_31 | Structural annotation | PF11195 | NA | NA |
| UHGV-0386307_32 | KOfam | K01448 | amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0386307_32 | PHROG | phrog_435 | endolysin | lysis |
| UHGV-0386307_32 | UniRef90 | UniRef90_A0A8G1TJN7 | MurNAc-LAA domain-containing protein | NA |
| UHGV-0386307_32 | eggNOG-mapper | 33035.JPJF01000090_gene96 | Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase | NA |
| UHGV-0386307_32 | Pfam | PF01832 | Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase | Glucosaminidase |
| UHGV-0386307_32 | Pfam | PF01520 | N-acetylmuramoyl-L-alanine amidase | Amidase_3 |
| UHGV-0386307_32 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0386307_32 | Pfam | PF01473 | Putative cell wall binding repeat | Choline_bind_1 |
| UHGV-0386307_32 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0386307_34 | KOfam | K14059 | int; integrase | NA |
| UHGV-0386307_34 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0386307_34 | UniRef90 | UniRef90_A0A8G1TMH5 | Site-specific integrase | NA |
| UHGV-0386307_34 | eggNOG-mapper | 33035.JPJF01000071_gene4457 | Phage integrase family | NA |
| UHGV-0386307_34 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-0386307_34 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0386307_34 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0386307_34 | Structural annotation | PF00589, PF14659, MF_02055, TIGR02224, COG4974 | NA | NA |
| UHGV-0386307_36 | KOfam | K07448 | mrr; restriction system protein | NA |
| UHGV-0386307_36 | PHROG | phrog_19856 | NA | unknown function |
| UHGV-0386307_36 | UniRef90 | UniRef90_UPI00148AF435 | restriction endonuclease | NA |
| UHGV-0386307_36 | eggNOG-mapper | 1235790.C805_00010 | Restriction endonuclease | NA |
| UHGV-0386307_36 | PADLOC | ZorD1_00005 | SWI2/SNF2 helicase, Mrr-like nuclease | Zorya |
| UHGV-0386307_36 | Pfam | PF04471 | Restriction endonuclease | Mrr_cat |
| UHGV-0386307_36 | COG | COG1787 | Endonuclease, HJR/Mrr/RecB family | NA |
| UHGV-0386307_37 | PHROG | phrog_87 | metallo-protease | other |
| UHGV-0386307_37 | UniRef90 | UniRef90_UPI00148B0062 | ImmA/IrrE family metallo-endopeptidase | NA |
| UHGV-0386307_37 | eggNOG-mapper | 318464.IO99_00420 | IrrE N-terminal-like domain | NA |
| UHGV-0386307_37 | Pfam | PF06114 | IrrE N-terminal-like domain | Peptidase_M78 |
| UHGV-0386307_37 | COG | COG2856 | Zn-dependent peptidase ImmA, M78 family | NA |
| UHGV-0386307_37 | Structural annotation | PF06114, COG2856 | NA | NA |
| UHGV-0386307_38 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0386307_38 | UniRef90 | UniRef90_UPI00148AF59D | helix-turn-helix domain-containing protein | NA |
| UHGV-0386307_38 | eggNOG-mapper | 411459.RUMOBE_00961 | Bacteriophage CI repressor helix-turn-helix domain | NA |
| UHGV-0386307_38 | Pfam | PF12844 | Helix-turn-helix domain | HTH_19 |
| UHGV-0386307_38 | COG | COG3093 | Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain | NA |
| UHGV-0386307_38 | Structural annotation | PF12844, NF041951, COG1396 | NA | NA |
| UHGV-0386307_39 | PHROG | phrog_8 | transcriptional regulator | transcription regulation |
| UHGV-0386307_39 | UniRef90 | UniRef90_UPI00051C781A | helix-turn-helix domain-containing protein | NA |
| UHGV-0386307_39 | Pfam | PF13443 | Cro/C1-type HTH DNA-binding domain | HTH_26 |
| UHGV-0386307_39 | COG | COG1396 | Transcriptional regulator, contains XRE-family HTH domain | NA |
| UHGV-0386307_39 | Structural annotation | PF01381, NF041951, COG1396 | NA | NA |
| UHGV-0386307_42 | PHROG | phrog_585 | NA | unknown function |
| UHGV-0386307_42 | UniRef90 | UniRef90_UPI00148B2334 | NA | NA |
| UHGV-0386307_42 | eggNOG-mapper | 543734.LCABL_13080 | NA | NA |
| UHGV-0386307_42 | Pfam | PF10711 | NA | DUF2513 |
| UHGV-0386307_42 | Structural annotation | PF10711, TIGR04176, COG1695 | NA | NA |
| UHGV-0386307_43 | PHROG | phrog_36464 | NA | unknown function |
| UHGV-0386307_43 | UniRef90 | UniRef90_R6QN85 | 50S ribosomal protein L11 domain protein | NA |
| UHGV-0386307_43 | eggNOG-mapper | 1235798.C817_05488 | NA | NA |
| UHGV-0386307_43 | Structural annotation | PF09035 | NA | NA |
| UHGV-0386307_47 | PHROG | phrog_22695 | NA | unknown function |
| UHGV-0386307_47 | eggNOG-mapper | 1235799.C818_04196 | NA | NA |
| UHGV-0386307_48 | PHROG | phrog_69 | exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0386307_48 | UniRef90 | UniRef90_UPI00148B25A9 | NA | NA |
| UHGV-0386307_48 | eggNOG-mapper | 1235799.C818_04197 | NA | NA |
| UHGV-0386307_48 | Pfam | PF10926 | NA | DUF2800 |
| UHGV-0386307_48 | COG | COG2887 | RecB family exonuclease | NA |
| UHGV-0386307_48 | Structural annotation | PF10926, MF_03030, TIGR00372, COG2887 | NA | NA |
| UHGV-0386307_49 | PHROG | phrog_112 | Gp2.5-like ssDNA binding protein and ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0386307_49 | UniRef90 | UniRef90_UPI00148B1F19 | NA | NA |
| UHGV-0386307_49 | eggNOG-mapper | 1235799.C818_04198 | NA | NA |
| UHGV-0386307_49 | Pfam | PF10991 | Enterobacter phage Enc34, ssDNA-binding protein | Enc34_ssDNA-bd |
| UHGV-0386307_49 | Structural annotation | PF10991, MF_04153, NF005241 | NA | NA |
| UHGV-0386307_50 | KOfam | K02334 | dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7] | NA |
| UHGV-0386307_50 | PHROG | phrog_17 | DNA polymerase | DNA, RNA and nucleotide metabolism |
| UHGV-0386307_50 | UniRef90 | UniRef90_A0A4R2K237 | DNA polymerase | NA |
| UHGV-0386307_50 | eggNOG-mapper | 1235799.C818_04199 | DNA polymerase A domain | NA |
| UHGV-0386307_50 | Pfam | PF00476 | DNA polymerase family A | DNA_pol_A |
| UHGV-0386307_50 | COG | COG0749 | DNA polymerase I, 3'-5' exonuclease and polymerase domains | NA |
| UHGV-0386307_50 | Structural annotation | PF00476, MF_04101, NF011540, COG0749 | NA | NA |
| UHGV-0386307_51 | PHROG | phrog_256 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0386307_51 | UniRef90 | UniRef90_UPI00148B11D4 | virulence-associated E family protein | NA |
| UHGV-0386307_51 | eggNOG-mapper | 1235799.C818_04200 | Virulence-associated protein E | NA |
| UHGV-0386307_51 | Pfam | PF05272 | Virulence-associated protein E-like domain | VapE-like_dom |
| UHGV-0386307_51 | COG | COG5545 | Predicted P-loop ATPase and inactivated derivatives | NA |
| UHGV-0386307_51 | Structural annotation | PF05272, NF011296, NF040562, COG5545 | NA | NA |
| UHGV-0386307_52 | PHROG | phrog_93 | endonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0386307_52 | UniRef90 | UniRef90_UPI00148B06C5 | VRR-NUC domain-containing protein | NA |
| UHGV-0386307_52 | eggNOG-mapper | 1235799.C818_04201 | VRR_NUC | NA |
| UHGV-0386307_52 | Pfam | PF08774 | VRR-NUC domain | VRR_NUC |
| UHGV-0386307_52 | Structural annotation | PF01870, MF_01490, NF002585, COG1591 | NA | NA |
| UHGV-0386307_53 | UniRef90 | UniRef90_A0A174K666 | DNA/RNA helicase, superfamily II, SNF2 family | NA |
| UHGV-0386307_53 | eggNOG-mapper | 1235799.C818_04202 | SNF2 family N-terminal domain | NA |
| UHGV-0386307_53 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-0386307_54 | KOfam | K14440 | SMARCAL1, HARP; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:5.6.2.-] | NA |
| UHGV-0386307_54 | PHROG | phrog_62 | DNA helicase | DNA, RNA and nucleotide metabolism |
| UHGV-0386307_54 | UniRef90 | UniRef90_UPI00148B31B1 | DEAD/DEAH box helicase | NA |
| UHGV-0386307_54 | eggNOG-mapper | 1235799.C818_04202 | SNF2 family N-terminal domain | NA |
| UHGV-0386307_54 | PADLOC | ZorD1_00007 | SWI2/SNF2 helicase, Mrr-like nuclease | Zorya |
| UHGV-0386307_54 | Pfam | PF00176 | SNF2-related domain | SNF2-rel_dom |
| UHGV-0386307_54 | Pfam | PF00271 | Helicase conserved C-terminal domain | Helicase_C |
| UHGV-0386307_54 | COG | COG0553 | Superfamily II DNA or RNA helicase, SNF2 family | NA |
| UHGV-0386307_54 | Structural annotation | PF16203, MF_01494, NF038318, COG0553 | NA | NA |
| UHGV-0386307_57 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0386307_57 | UniRef90 | UniRef90_UPI00148B00F2 | sigma-70 family RNA polymerase sigma factor | NA |
| UHGV-0386307_57 | eggNOG-mapper | 1235792.C808_03069 | sigma factor activity | NA |
| UHGV-0386307_57 | Pfam | PF04545 | Sigma-70, region 4 | Sigma70_r4 |
| UHGV-0386307_57 | COG | COG1191 | DNA-directed RNA polymerase specialized sigma subunit | NA |
| UHGV-0386307_57 | Structural annotation | PF07374, MF_00674, NF007227, COG1342 | NA | NA |
| UHGV-0386307_58 | PHROG | phrog_606 | terminase small subunit | head and packaging |
| UHGV-0386307_58 | UniRef90 | UniRef90_UPI001D088AD3 | DNA-packaging protein | NA |