| UHGV-0392649_1 | PHROG | phrog_478 | site-specific recombination directionality factor RDF | integration and excision |
| UHGV-0392649_1 | UniRef90 | UniRef90_R6R5K5 | Protein 64 protein | NA |
| UHGV-0392649_1 | eggNOG-mapper | 1111121.HMPREF1247_0834 | NA | NA |
| UHGV-0392649_2 | PHROG | phrog_172 | head scaffolding protein | head and packaging |
| UHGV-0392649_2 | UniRef90 | UniRef90_A0A415FLT0 | NA | NA |
| UHGV-0392649_2 | eggNOG-mapper | 742733.HMPREF9469_01824 | NA | NA |
| UHGV-0392649_2 | Pfam | PF14265 | NA | DUF4355 |
| UHGV-0392649_2 | Structural annotation | PF14265 | NA | NA |
| UHGV-0392649_3 | PHROG | phrog_422 | major head protein | head and packaging |
| UHGV-0392649_3 | UniRef90 | UniRef90_A0A2H4JCM6 | Putative capsid protein | NA |
| UHGV-0392649_3 | eggNOG-mapper | 742733.HMPREF9469_01823 | NA | NA |
| UHGV-0392649_3 | Structural annotation | PF21703, MF_04119, TIGR04387, COG4834 | NA | NA |
| UHGV-0392649_4 | PHROG | phrog_2724 | NA | unknown function |
| UHGV-0392649_4 | UniRef90 | UniRef90_A0A564VY53 | Rho_N domain-containing protein | NA |
| UHGV-0392649_4 | Pfam | PF07498 | Rho termination factor, N-terminal domain | Rho_N |
| UHGV-0392649_4 | Structural annotation | PF07498 | NA | NA |
| UHGV-0392649_5 | PHROG | phrog_132 | head-tail adaptor | connector |
| UHGV-0392649_5 | UniRef90 | UniRef90_A0A173WLV7 | Phage gp6-like head-tail connector protein | NA |
| UHGV-0392649_5 | eggNOG-mapper | 742733.HMPREF9469_01821 | Phage gp6-like head-tail connector protein | NA |
| UHGV-0392649_5 | Pfam | PF05135 | Phage gp6-like head-tail connector protein | Phage_connect_1 |
| UHGV-0392649_5 | Structural annotation | PF05135 | NA | NA |
| UHGV-0392649_6 | PHROG | phrog_2168 | NA | unknown function |
| UHGV-0392649_6 | eggNOG-mapper | 742733.HMPREF9469_01820 | NA | NA |
| UHGV-0392649_6 | Structural annotation | PF07405, TIGR01563, COG5614 | NA | NA |
| UHGV-0392649_7 | PHROG | phrog_5 | tail completion or Neck1 protein | connector |
| UHGV-0392649_7 | UniRef90 | UniRef90_UPI001D01C150 | HK97 gp10 family phage protein | NA |
| UHGV-0392649_7 | eggNOG-mapper | 742733.HMPREF9469_01819 | Bacteriophage HK97-gp10, putative tail-component | NA |
| UHGV-0392649_7 | Pfam | PF04883 | Bacteriophage HK97-gp10, putative tail-component | HK97-gp10_like |
| UHGV-0392649_7 | NCBIFam | TIGR01725.1 | HK97-gp10 family putative phage morphogenesis protein | NA |
| UHGV-0392649_7 | Structural annotation | PF20039, TIGR01725, COG5005 | NA | NA |
| UHGV-0392649_8 | PHROG | phrog_78 | tail terminator | connector |
| UHGV-0392649_8 | eggNOG-mapper | 1235800.C819_00480 | NA | NA |
| UHGV-0392649_8 | Structural annotation | PF05657 | NA | NA |
| UHGV-0392649_9 | PHROG | phrog_158 | major tail protein | tail |
| UHGV-0392649_9 | UniRef90 | UniRef90_A0A1M7JWZ7 | Phage tail tube protein, TTP | NA |
| UHGV-0392649_9 | eggNOG-mapper | 742733.HMPREF9469_01817 | Phage tail tube protein, TTP | NA |
| UHGV-0392649_9 | Pfam | PF08813 | Phage tail tube protein, TTP | Phage_tail_3 |
| UHGV-0392649_9 | Structural annotation | PF16463, TIGR02241, COG5437 | NA | NA |
| UHGV-0392649_10 | PHROG | phrog_183 | tail chaperone protein | tail |
| UHGV-0392649_10 | UniRef90 | UniRef90_UPI0011DE12FE | NA | NA |
| UHGV-0392649_10 | eggNOG-mapper | 1280689.AUJC01000003_gene974 | NA | NA |
| UHGV-0392649_10 | Pfam | PF19591 | NA | DUF6096 |
| UHGV-0392649_10 | Structural annotation | PF19591 | NA | NA |
| UHGV-0392649_11 | KOfam | K08757 | APOA1; apolipoprotein A-I | NA |
| UHGV-0392649_11 | PHROG | phrog_167 | tail length tape measure protein | tail |
| UHGV-0392649_11 | UniRef90 | UniRef90_UPI00131A0471 | transglycosylase SLT domain-containing protein | NA |
| UHGV-0392649_11 | eggNOG-mapper | 397290.C810_01419 | Transglycosylase SLT domain | NA |
| UHGV-0392649_11 | Pfam | PF01464 | Transglycosylase SLT domain | SLT |
| UHGV-0392649_11 | COG | COG1280 | Threonine/homoserine/homoserine lactone efflux protein | NA |
| UHGV-0392649_12 | PHROG | phrog_1194 | NA | unknown function |
| UHGV-0392649_12 | eggNOG-mapper | 1121866.AUGK01000003_gene1438 | NA | NA |
| UHGV-0392649_12 | Pfam | PF20458 | NA | DUF6711 |
| UHGV-0392649_12 | Structural annotation | PF20458, TIGR02126, COG3499 | NA | NA |
| UHGV-0392649_13 | PHROG | phrog_6616 | tail protein | tail |
| UHGV-0392649_13 | UniRef90 | UniRef90_UPI0015714EA8 | tail fiber domain-containing protein | NA |
| UHGV-0392649_13 | eggNOG-mapper | 476272.RUMHYD_01992 | NA | NA |
| UHGV-0392649_13 | Pfam | PF13884 | Chaperone of endosialidase | Peptidase_S74 |
| UHGV-0392649_13 | Structural annotation | PF05954, NF033848, COG3500 | NA | NA |
| UHGV-0392649_14 | UniRef90 | UniRef90_A0A564VXL8 | Bacterial Ig-like domain (Group 2) | NA |
| UHGV-0392649_14 | Structural annotation | PF01301, PF03944, MF_00279, NF040743, COG3622 | NA | NA |
| UHGV-0392649_15 | PHROG | phrog_4105 | NA | unknown function |
| UHGV-0392649_15 | eggNOG-mapper | 411459.RUMOBE_00911 | NA | NA |
| UHGV-0392649_16 | PHROG | phrog_1129 | holin | lysis |
| UHGV-0392649_16 | UniRef90 | UniRef90_UPI00051B7422 | phage holin family protein | NA |
| UHGV-0392649_16 | eggNOG-mapper | 1232453.BAIF02000030_gene2527 | NA | NA |
| UHGV-0392649_16 | Pfam | PF16079 | Phage holin family Hol44, in holin superfamily V | Phage_holin_5_2 |
| UHGV-0392649_16 | Structural annotation | PF16079 | NA | NA |
| UHGV-0392649_17 | KOfam | K01447 | xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] | NA |
| UHGV-0392649_17 | PHROG | phrog_3088 | amidase | lysis |
| UHGV-0392649_17 | UniRef90 | UniRef90_A0A416S3E7 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0392649_17 | eggNOG-mapper | 180332.JTGN01000004_gene2267 | Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase | NA |
| UHGV-0392649_17 | Pfam | PF01510 | N-acetylmuramoyl-L-alanine amidase | Amidase_2 |
| UHGV-0392649_17 | Pfam | PF01471 | Putative peptidoglycan binding domain | PG_binding_1 |
| UHGV-0392649_17 | COG | COG0860 | N-acetylmuramoyl-L-alanine amidase | NA |
| UHGV-0392649_17 | Structural annotation | PF01510, PF18342, MF_04111, NF008758, COG5632 | NA | NA |
| UHGV-0392649_18 | KOfam | K14059 | int; integrase | NA |
| UHGV-0392649_18 | PHROG | phrog_1 | integrase | integration and excision |
| UHGV-0392649_18 | UniRef90 | UniRef90_A0A174AZK7 | Site-specific tyrosine recombinase XerC | NA |
| UHGV-0392649_18 | eggNOG-mapper | 411902.CLOBOL_02558 | Belongs to the 'phage' integrase family | NA |
| UHGV-0392649_18 | Pfam | PF14657 | Arm DNA-binding domain | Arm-DNA-bind_4 |
| UHGV-0392649_18 | Pfam | PF14659 | Phage integrase, N-terminal SAM-like domain | Phage_int_SAM_3 |
| UHGV-0392649_18 | Pfam | PF00589 | Phage integrase family | Phage_integrase |
| UHGV-0392649_18 | COG | COG0582 | Integrase/recombinase, includes phage integrase | NA |
| UHGV-0392649_18 | Structural annotation | PF00589, PF14659, PF14657, MF_01808, TIGR02224, COG4974 | NA | NA |
| UHGV-0392649_19 | UniRef90 | UniRef90_UPI001D02BD1B | zinc-ribbon domain-containing protein | NA |
| UHGV-0392649_19 | eggNOG-mapper | 1280696.ATVY01000093_gene1442 | NA | NA |
| UHGV-0392649_19 | Pfam | PF13248 | zinc-ribbon domain | zf-ribbon_3 |
| UHGV-0392649_20 | PHROG | phrog_87 | metallo-protease | other |
| UHGV-0392649_20 | UniRef90 | UniRef90_F7JQG6 | Peptidase_M78 domain-containing protein | NA |
| UHGV-0392649_20 | eggNOG-mapper | 1256908.HMPREF0373_00642 | Zn peptidase | NA |
| UHGV-0392649_20 | Pfam | PF06114 | IrrE N-terminal-like domain | Peptidase_M78 |
| UHGV-0392649_20 | COG | COG2856 | Zn-dependent peptidase ImmA, M78 family | NA |
| UHGV-0392649_20 | Structural annotation | PF06114, COG2856 | NA | NA |
| UHGV-0392649_21 | KOfam | K22300 | dicA; HTH-type transcriptional regulator, cell division transcriptional repressor | NA |
| UHGV-0392649_21 | PHROG | phrog_2967 | transcriptional regulator | transcription regulation |
| UHGV-0392649_21 | UniRef90 | UniRef90_A0A396P1S7 | XRE family transcriptional regulator | NA |
| UHGV-0392649_21 | eggNOG-mapper | 1256908.HMPREF0373_00643 | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair | NA |
| UHGV-0392649_21 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0392649_21 | COG | COG1974 | SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase) | NA |
| UHGV-0392649_21 | Structural annotation | PF12844, MF_00535, NF007257, COG1396 | NA | NA |
| UHGV-0392649_22 | UniRef90 | UniRef90_A0A396PLE3 | NA | NA |
| UHGV-0392649_22 | eggNOG-mapper | 257314.LJ_1456 | NA | NA |
| UHGV-0392649_22 | Pfam | PF05339 | NA | DUF739 |
| UHGV-0392649_22 | COG | COG3655 | DNA-binding transcriptional regulator, XRE family | NA |
| UHGV-0392649_22 | Structural annotation | PF05339, NF002773, COG1476 | NA | NA |
| UHGV-0392649_23 | KOfam | K07741 | antB; anti-repressor protein | NA |
| UHGV-0392649_23 | PHROG | phrog_63 | anti-repressor Ant | transcription regulation |
| UHGV-0392649_23 | UniRef90 | UniRef90_A0A417WXZ3 | Oxidoreductase | NA |
| UHGV-0392649_23 | eggNOG-mapper | 658655.HMPREF0988_02592 | AntA/AntB antirepressor | NA |
| UHGV-0392649_23 | Pfam | PF08346 | AntA/AntB antirepressor | AntA |
| UHGV-0392649_23 | Pfam | PF03374 | Phage antirepressor protein KilAC domain | ANT |
| UHGV-0392649_23 | COG | COG3561 | Phage anti-repressor protein Ant | NA |
| UHGV-0392649_23 | Structural annotation | PF03374, PF08346, TIGR02681, COG3645, COG3561 | NA | NA |
| UHGV-0392649_24 | PHROG | phrog_6058 | NA | unknown function |
| UHGV-0392649_24 | UniRef90 | UniRef90_UPI001C00DBC2 | helix-turn-helix domain-containing protein | NA |
| UHGV-0392649_24 | eggNOG-mapper | 748224.HMPREF9436_01450 | NA | NA |
| UHGV-0392649_24 | Pfam | PF01381 | Helix-turn-helix | HTH_3 |
| UHGV-0392649_24 | Structural annotation | PF01381, PF12728, MF_00535, NF041951, COG1396 | NA | NA |
| UHGV-0392649_26 | PHROG | phrog_434 | RecE-like recombination exonuclease | DNA, RNA and nucleotide metabolism |
| UHGV-0392649_26 | UniRef90 | UniRef90_A0A844E6Y4 | Recombinase | NA |
| UHGV-0392649_26 | eggNOG-mapper | 1095750.HMPREF9970_1677 | YqaJ viral recombinase family | NA |
| UHGV-0392649_26 | Pfam | PF09588 | YqaJ-like viral recombinase domain | YqaJ |
| UHGV-0392649_26 | NCBIFam | TIGR03033.1 | putative phage-type endonuclease | NA |
| UHGV-0392649_26 | COG | COG5377 | Phage-related protein, predicted endonuclease | NA |
| UHGV-0392649_26 | Structural annotation | PF09588, MF_03030, TIGR03033, COG5377 | NA | NA |
| UHGV-0392649_27 | PHROG | phrog_674 | NA | unknown function |
| UHGV-0392649_27 | UniRef90 | UniRef90_UPI001C1259C1 | NA | NA |
| UHGV-0392649_27 | eggNOG-mapper | 1095750.HMPREF9970_1676 | NA | NA |
| UHGV-0392649_27 | Pfam | PF07083 | NA | DUF1351 |
| UHGV-0392649_27 | Structural annotation | PF07083 | NA | NA |
| UHGV-0392649_28 | KOfam | K07455 | recT; recombination protein RecT | NA |
| UHGV-0392649_28 | PHROG | phrog_148 | RecT-like ssDNA annealing protein | DNA, RNA and nucleotide metabolism |
| UHGV-0392649_28 | UniRef90 | UniRef90_A0A2N5PKF9 | Recombinase | NA |
| UHGV-0392649_28 | eggNOG-mapper | 1095750.HMPREF9970_1675 | RecT family | NA |
| UHGV-0392649_28 | Pfam | PF03837 | RecT family | RecT |
| UHGV-0392649_28 | NCBIFam | TIGR00616.1 | recombinase, phage RecT family | NA |
| UHGV-0392649_28 | COG | COG3723 | Recombinational DNA repair protein RecT | NA |
| UHGV-0392649_28 | Structural annotation | PF03837, TIGR00616, COG3723 | NA | NA |
| UHGV-0392649_29 | PHROG | phrog_997 | replication terminator | DNA, RNA and nucleotide metabolism |
| UHGV-0392649_29 | eggNOG-mapper | 1298920.KI911353_gene2719 | NA | NA |
| UHGV-0392649_30 | PHROG | phrog_1029 | NA | unknown function |
| UHGV-0392649_30 | UniRef90 | UniRef90_A0A3D5WKT6 | Peptidase S59 domain-containing protein | NA |
| UHGV-0392649_30 | eggNOG-mapper | 1232453.BAIF02000057_gene1140 | NA | NA |
| UHGV-0392649_30 | Structural annotation | PF10065, COG5532 | NA | NA |
| UHGV-0392649_31 | KOfam | K03111 | ssb; single-strand DNA-binding protein | NA |
| UHGV-0392649_31 | PHROG | phrog_44 | single strand DNA binding protein | DNA, RNA and nucleotide metabolism |
| UHGV-0392649_31 | UniRef90 | UniRef90_A0A174S775 | Single-stranded DNA-binding protein | NA |
| UHGV-0392649_31 | eggNOG-mapper | 622312.ROSEINA2194_04345 | Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism | NA |
| UHGV-0392649_31 | Pfam | PF00436 | Single-strand binding protein family | SSB |
| UHGV-0392649_31 | NCBIFam | TIGR00621.2 | single-stranded DNA-binding protein | NA |
| UHGV-0392649_31 | COG | COG0629 | Single-stranded DNA-binding protein | NA |
| UHGV-0392649_31 | HAMAP | MF_00984 | Single-stranded DNA-binding protein | NA |
| UHGV-0392649_31 | Structural annotation | PF00436, MF_00984, NF005580, COG0629 | NA | NA |
| UHGV-0392649_32 | PHROG | phrog_244 | RusA-like Holliday junction resolvase | DNA, RNA and nucleotide metabolism |
| UHGV-0392649_32 | UniRef90 | UniRef90_A0A841R0Q1 | Holliday junction resolvase | NA |
| UHGV-0392649_32 | eggNOG-mapper | 1304866.K413DRAFT_1199 | NA | NA |
| UHGV-0392649_32 | Structural annotation | PF01870, MF_01490, COG1591 | NA | NA |
| UHGV-0392649_33 | PHROG | phrog_10469 | DnaD-like helicase loader | DNA, RNA and nucleotide metabolism |
| UHGV-0392649_33 | UniRef90 | UniRef90_A0A2N5NVH3 | Phage_rep_org_N domain-containing protein | NA |
| UHGV-0392649_33 | eggNOG-mapper | 411470.RUMGNA_02197 | phage replisome | NA |
| UHGV-0392649_33 | Pfam | PF09681 | N-terminal phage replisome organiser (Phage_rep_org_N) | Phage_rep_org_N |
| UHGV-0392649_33 | NCBIFam | TIGR01714.1 | phage replisome organizer, putative, N-terminal region | NA |
| UHGV-0392649_33 | Structural annotation | PF09681, TIGR01714, COG3388 | NA | NA |
| UHGV-0392649_34 | Structural annotation | PF02796, NF040595 | NA | NA |
| UHGV-0392649_38 | KOfam | K00558 | DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] | NA |
| UHGV-0392649_38 | PHROG | phrog_116 | DNA methyltransferase | other |
| UHGV-0392649_38 | UniRef90 | UniRef90_UPI001C01F8F2 | DNA cytosine methyltransferase | NA |
| UHGV-0392649_38 | eggNOG-mapper | 742740.HMPREF9474_04317 | C-5 cytosine-specific DNA methylase | NA |
| UHGV-0392649_38 | PADLOC | MTase_II_00020 | Type II methyltransferase | RM |
| UHGV-0392649_38 | Pfam | PF00145 | C-5 cytosine-specific DNA methylase | DNA_methylase |
| UHGV-0392649_38 | COG | COG0270 | DNA-cytosine methylase | NA |
| UHGV-0392649_38 | Structural annotation | PF00145, MF_00351, TIGR00675, COG0270 | NA | NA |
| UHGV-0392649_39 | PHROG | phrog_36 | transcriptional regulator | transcription regulation |
| UHGV-0392649_39 | UniRef90 | UniRef90_A0A174SAH0 | RNA polymerase sigma factor, sigma-70 family | NA |
| UHGV-0392649_39 | eggNOG-mapper | 1235792.C808_05326 | NA | NA |
| UHGV-0392649_39 | Structural annotation | PF02996 | NA | NA |
| UHGV-0392649_41 | PHROG | phrog_1889 | terminase small subunit | head and packaging |
| UHGV-0392649_41 | UniRef90 | UniRef90_A0A373P435 | Terminase | NA |
| UHGV-0392649_41 | eggNOG-mapper | 33035.JPJF01000107_gene435 | NA | NA |
| UHGV-0392649_41 | Pfam | PF10668 | Phage terminase small subunit | Phage_terminase |
| UHGV-0392649_41 | NCBIFam | NF040601.1 | phage terminase small subunit | NA |
| UHGV-0392649_41 | COG | COG5484 | NA | NA |
| UHGV-0392649_41 | Structural annotation | PF06056, NF040601, COG5484 | NA | NA |
| UHGV-0392649_42 | KOfam | K06909 | xtmB; phage terminase large subunit | NA |
| UHGV-0392649_42 | PHROG | phrog_10250 | NA | unknown function |
| UHGV-0392649_42 | UniRef90 | UniRef90_UPI00156F5FD7 | PBSX family phage terminase large subunit | NA |
| UHGV-0392649_42 | eggNOG-mapper | 903814.ELI_3215 | Phage terminase large subunit | NA |
| UHGV-0392649_42 | Pfam | PF03237 | Terminase large subunit, T4likevirus-type, N-terminal | Terminase_6N |
| UHGV-0392649_42 | NCBIFam | TIGR01547.1 | PBSX family phage terminase large subunit | NA |
| UHGV-0392649_42 | COG | COG1783 | Phage terminase large subunit | NA |
| UHGV-0392649_42 | Structural annotation | PF04466, PF20454, MF_04148, TIGR01547, COG1783 | NA | NA |
| UHGV-0392649_43 | PHROG | phrog_64 | portal protein | head and packaging |
| UHGV-0392649_43 | UniRef90 | UniRef90_A0A416N3J2 | Phage portal protein | NA |
| UHGV-0392649_43 | eggNOG-mapper | 742733.HMPREF9469_01826 | Phage portal protein, SPP1 family | NA |
| UHGV-0392649_43 | Pfam | PF05133 | Phage portal protein, SPP1 Gp6-like | Phage_prot_Gp6 |
| UHGV-0392649_43 | NCBIFam | TIGR01538.1 | phage portal protein | NA |
| UHGV-0392649_43 | Structural annotation | PF05133, MF_04120, TIGR01538, COG3567 | NA | NA |
| UHGV-0392649_44 | PHROG | phrog_2841 | minor head protein | head and packaging |
| UHGV-0392649_44 | UniRef90 | UniRef90_UPI00157127C3 | minor capsid protein | NA |
| UHGV-0392649_44 | eggNOG-mapper | 742733.HMPREF9469_01825 | Phage head morphogenesis protein, SPP1 gp7 family | NA |
| UHGV-0392649_44 | Pfam | PF04233 | Phage Mu protein F like protein | Phage_Mu_F |
| UHGV-0392649_44 | NCBIFam | TIGR01641.1 | minor capsid protein | NA |
| UHGV-0392649_44 | COG | COG2369 | NA | NA |
| UHGV-0392649_44 | Structural annotation | PF04233, TIGR01641, COG2369 | NA | NA |
| UHGV-0392649_45 | Structural annotation | PF11344 | NA | NA |
| UHGV-0392649_46 | PHROG | phrog_30750 | NA | unknown function |
| UHGV-0392649_47 | PHROG | phrog_1048 | NA | unknown function |
| UHGV-0392649_47 | UniRef90 | UniRef90_A0A396MNX1 | NA | NA |
| UHGV-0392649_47 | eggNOG-mapper | 457412.RSAG_01107 | NA | NA |
| UHGV-0392649_47 | Pfam | PF11195 | NA | DUF2829 |
| UHGV-0392649_47 | dbAPIS | APIS029 | Tad2 is a "sponge" that sequesters the immune signaling molecules produced by Thoeris TIR-domain proteins in response to phage. | NA |
| UHGV-0392649_47 | Structural annotation | PF11195 | NA | NA |
| UHGV-0392649_48 | PHROG | phrog_918 | NA | unknown function |
| UHGV-0392649_48 | UniRef90 | UniRef90_UPI00115A7D93 | NA | NA |
| UHGV-0392649_48 | eggNOG-mapper | 298338.Q5ULN6_9CAUD | NA | NA |
| UHGV-0392649_48 | Pfam | PF19791 | NA | DUF6275 |
| UHGV-0392649_48 | Structural annotation | PF19791 | NA | NA |